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Overview

ID MAG04207
Name WLSH2_bin.32
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Chromatiales
Family Chromatiaceae
Genus M0108
Species M0108 sp041307365
Assembly information
Completeness (%) 87.3
Contamination (%) 4.81
GC content (%) 64.0
N50 (bp) 10,987
Genome size (bp) 2,626,219

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2612

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_1002317_0 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.0 1239.0
WLSH2_k127_1002317_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 468.0
WLSH2_k127_1002317_10 - - - - 0.000000000000000000000000000000000000004061 149.0
WLSH2_k127_1002317_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000001334 122.0
WLSH2_k127_1002317_12 Protein of unknown function (DUF533) - - - 0.000000000000000002557 87.0
WLSH2_k127_1002317_13 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000003966 70.0
WLSH2_k127_1002317_2 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 466.0
WLSH2_k127_1002317_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 421.0
WLSH2_k127_1002317_4 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 390.0
WLSH2_k127_1002317_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 297.0
WLSH2_k127_1002317_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 300.0
WLSH2_k127_1002317_7 - - - - 0.0000000000000000000000000000000000000000000000002531 180.0
WLSH2_k127_1002317_8 Belongs to the HSP15 family K04762 - - 0.000000000000000000000000000000000000000000000001928 177.0
WLSH2_k127_1002317_9 PFAM Smr - - - 0.00000000000000000000000000000000000000000000002592 172.0
WLSH2_k127_10068153_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 525.0
WLSH2_k127_10068153_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 486.0
WLSH2_k127_10068153_2 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 361.0
WLSH2_k127_10068153_3 TIGRFAM small redox-active disulfide protein 2 - - - 0.00000000000000000000000000000003142 127.0
WLSH2_k127_10068153_4 TIGRFAM Arsenical-resistance protein K03325 - - 0.0000164 57.0
WLSH2_k127_10073045_0 Histidine kinase - - - 1.643e-249 798.0
WLSH2_k127_10073045_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 407.0
WLSH2_k127_10073045_10 polysaccharide biosynthetic process - - - 0.0000000000000003436 92.0
WLSH2_k127_10073045_11 Domain of unknown function (DUF4276) - - - 0.00000000131 65.0
WLSH2_k127_10073045_12 Virulence protein RhuM family - - - 0.00000000231 70.0
WLSH2_k127_10073045_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 380.0
WLSH2_k127_10073045_3 response regulator receiver K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 349.0
WLSH2_k127_10073045_4 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 306.0
WLSH2_k127_10073045_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 269.0
WLSH2_k127_10073045_6 Calcium/calmodulin dependent protein kinase II association domain - - - 0.00000000000000000000000000000000000000000000000007183 181.0
WLSH2_k127_10073045_7 PFAM Bacterial transferase hexapeptide (three repeats) - - - 0.00000000000000000000000000009062 123.0
WLSH2_k127_10073045_8 sigma factor antagonist activity K04757,K20977 - 2.7.11.1 0.000000000000000004304 91.0
WLSH2_k127_10073045_9 antisigma factor binding K04749 - - 0.0000000000000001839 84.0
WLSH2_k127_10112879_0 Sulfate transporter antisigma-factor antagonist STAS - - - 1.149e-319 991.0
WLSH2_k127_10112879_1 Sulfate transporter antisigma-factor antagonist STAS - - - 5.836e-288 899.0
WLSH2_k127_10112879_2 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01758,K01761 - 4.4.1.1,4.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 314.0
WLSH2_k127_10141216_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 8.256e-321 988.0
WLSH2_k127_10141216_1 PFAM Cysteine-rich - - - 1.86e-242 756.0
WLSH2_k127_10141216_10 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000000000002291 121.0
WLSH2_k127_10141216_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 3.314e-203 640.0
WLSH2_k127_10141216_3 PFAM NADH Ubiquinone K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 598.0
WLSH2_k127_10141216_4 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 365.0
WLSH2_k127_10141216_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 329.0
WLSH2_k127_10141216_6 PFAM Peptidase A31, hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000000000000000003751 205.0
WLSH2_k127_10141216_7 - - - - 0.0000000000000000000000000000000000000000000001833 171.0
WLSH2_k127_10141216_8 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000001449 168.0
WLSH2_k127_10141216_9 PFAM HupH hydrogenase expression protein, C-terminal conserved region K03618 - - 0.0000000000000000000000000000000000000005559 152.0
WLSH2_k127_10154835_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 484.0
WLSH2_k127_10154835_1 - - - - 0.000000000000000000000000000005322 124.0
WLSH2_k127_10154835_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000002369 130.0
WLSH2_k127_10154835_3 OsmC-like protein - - - 0.000000000000000002679 87.0
WLSH2_k127_1020778_0 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000002774 208.0
WLSH2_k127_10231922_0 Hydrophobe Amphiphile Efflux-1 (HAE1) K03296,K18138 - - 0.0 1767.0
WLSH2_k127_10231922_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 505.0
WLSH2_k127_10231922_2 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 423.0
WLSH2_k127_10231922_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 424.0
WLSH2_k127_10231922_4 PFAM Alpha beta hydrolase of - - - 0.0000000000000000000000000000000000000000000005402 169.0
WLSH2_k127_10231922_5 methyltransferase - - - 0.000000000000000000000000000001052 121.0
WLSH2_k127_10232023_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 323.0
WLSH2_k127_10232023_1 MazG-like family - - - 0.00000000000000000000000000000000000000000003827 161.0
WLSH2_k127_10232023_2 - - - - 0.00000000000000000000003446 104.0
WLSH2_k127_10307303_0 Exporters of the RND superfamily K07003 - - 0.0 1258.0
WLSH2_k127_10307303_1 N-Acetylmuramoyl-L-alanine amidase - - - 3.877e-275 862.0
WLSH2_k127_10307303_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.46e-236 737.0
WLSH2_k127_10307303_4 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000007405 166.0
WLSH2_k127_10307303_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000005802 83.0
WLSH2_k127_10316066_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 528.0
WLSH2_k127_10316066_1 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 458.0
WLSH2_k127_10316066_2 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 395.0
WLSH2_k127_10324103_0 PFAM malic K00029 - 1.1.1.40 0.0 1072.0
WLSH2_k127_10324103_1 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000001428 126.0
WLSH2_k127_10349138_0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0 1158.0
WLSH2_k127_10349138_1 Type III effector Hrp-dependent - - - 5.197e-200 631.0
WLSH2_k127_10375515_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 439.0
WLSH2_k127_10375515_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 332.0
WLSH2_k127_10375515_2 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000001533 226.0
WLSH2_k127_10375515_3 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000001462 151.0
WLSH2_k127_10375515_4 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.000000000000000000000000000000000002478 142.0
WLSH2_k127_10386740_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01571 - 4.1.1.3 8.556e-286 888.0
WLSH2_k127_10386740_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 8.457e-218 690.0
WLSH2_k127_10386740_2 decarboxylase beta subunit K01572 - 4.1.1.3 1.411e-198 623.0
WLSH2_k127_10386740_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 9.059e-194 610.0
WLSH2_k127_10386740_4 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000171 147.0
WLSH2_k127_10386740_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000006681 105.0
WLSH2_k127_10386740_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000005145 100.0
WLSH2_k127_10386740_7 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000000005292 86.0
WLSH2_k127_10386740_8 Lyase and sodium transporter K01573 - 4.1.1.3 0.0000000000009367 76.0
WLSH2_k127_10391750_0 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 451.0
WLSH2_k127_10391750_1 transposase - - - 0.0000000000000000000000000000000000000001175 159.0
WLSH2_k127_10391750_2 - - - - 0.0000000001263 66.0
WLSH2_k127_10391750_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000001014 55.0
WLSH2_k127_10391750_4 - - - - 0.0000002482 55.0
WLSH2_k127_10416688_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 329.0
WLSH2_k127_10416688_1 PFAM LppC K07121 - - 0.0000000000000000000000000000000007713 142.0
WLSH2_k127_10450472_0 Belongs to the glycosyl hydrolase 57 family - - - 5.503e-275 852.0
WLSH2_k127_10450472_1 Belongs to the glycosyl hydrolase 57 family - - - 8.887e-197 623.0
WLSH2_k127_10450472_2 - - - - 0.0000000000000000000000002814 107.0
WLSH2_k127_10503302_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 436.0
WLSH2_k127_10503302_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 419.0
WLSH2_k127_10509676_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 526.0
WLSH2_k127_10509676_1 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 341.0
WLSH2_k127_10509676_2 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 312.0
WLSH2_k127_10509676_3 TraB family K09973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004011 280.0
WLSH2_k127_10509676_4 intermediate-associated protein 30 - - - 0.0000000000000000000000000000000000000000000000000000000005995 211.0
WLSH2_k127_10509676_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000001007 151.0
WLSH2_k127_10509676_6 - - - - 0.000000006287 63.0
WLSH2_k127_10509676_7 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000001981 60.0
WLSH2_k127_10532287_0 Sulfate permease family - - - 3.411e-250 781.0
WLSH2_k127_10532287_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 468.0
WLSH2_k127_10532287_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 407.0
WLSH2_k127_10532287_3 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 336.0
WLSH2_k127_10532287_4 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 337.0
WLSH2_k127_10532287_5 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000001864 164.0
WLSH2_k127_10532287_6 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000001433 149.0
WLSH2_k127_10532287_7 signal sequence binding - - - 0.0000000000000000000000002531 115.0
WLSH2_k127_10538560_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.221e-284 882.0
WLSH2_k127_10538560_1 Cytochrome D1 heme domain - - - 2.786e-208 662.0
WLSH2_k127_10538560_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 381.0
WLSH2_k127_10538560_3 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000107 113.0
WLSH2_k127_1056896_0 SMART Nucleotide binding protein, PINc K07175 - - 9.222e-240 748.0
WLSH2_k127_1056896_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 458.0
WLSH2_k127_1056896_2 NlpB/DapX lipoprotein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 444.0
WLSH2_k127_1056896_3 PFAM Amino acid-binding ACT K03567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 321.0
WLSH2_k127_1056896_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 279.0
WLSH2_k127_1056896_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000004264 234.0
WLSH2_k127_1056896_6 excinuclease ABC activity - - - 0.00000000000000000005438 91.0
WLSH2_k127_1061472_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 589.0
WLSH2_k127_1061472_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 556.0
WLSH2_k127_1061472_2 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 480.0
WLSH2_k127_1061472_3 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 483.0
WLSH2_k127_1061472_4 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 453.0
WLSH2_k127_1061472_5 membrane-bound metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002008 255.0
WLSH2_k127_1061472_6 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002452 248.0
WLSH2_k127_1061472_7 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000378 156.0
WLSH2_k127_1061472_8 penicillin-binding protein K05364 - - 0.0000000000000000000000000000000000001659 142.0
WLSH2_k127_10662745_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2400.0
WLSH2_k127_10662745_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2379.0
WLSH2_k127_10662745_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000002091 175.0
WLSH2_k127_10662745_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000266 84.0
WLSH2_k127_10662745_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000001172 82.0
WLSH2_k127_10662745_13 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000003092 56.0
WLSH2_k127_10662745_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1161.0
WLSH2_k127_10662745_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 368.0
WLSH2_k127_10662745_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006864 309.0
WLSH2_k127_10662745_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001163 279.0
WLSH2_k127_10662745_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001557 276.0
WLSH2_k127_10662745_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002154 250.0
WLSH2_k127_10662745_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000001252 238.0
WLSH2_k127_10662745_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000000000000000000000000000004328 186.0
WLSH2_k127_10788839_0 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 484.0
WLSH2_k127_10788839_1 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 360.0
WLSH2_k127_10788839_2 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004912 279.0
WLSH2_k127_10788839_3 Belongs to the peptidase S16 family - - - 0.0000000000003417 69.0
WLSH2_k127_10788839_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000001709 61.0
WLSH2_k127_10788839_5 replication factor c - - - 0.00009384 47.0
WLSH2_k127_10791381_0 VWA-like domain (DUF2201) - - - 2.639e-202 636.0
WLSH2_k127_10791381_1 associated with various cellular activities - - - 1.065e-196 619.0
WLSH2_k127_10791381_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 592.0
WLSH2_k127_10791381_3 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 538.0
WLSH2_k127_10791381_4 Isocitrate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 409.0
WLSH2_k127_10791381_5 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000005559 215.0
WLSH2_k127_10791381_6 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000002735 203.0
WLSH2_k127_10791381_7 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000001481 137.0
WLSH2_k127_10791381_8 - - - - 0.000000000000000000000000000000003977 135.0
WLSH2_k127_10791381_9 RNA-binding protein - - - 0.0000000007917 63.0
WLSH2_k127_10791484_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 348.0
WLSH2_k127_10791484_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000001337 181.0
WLSH2_k127_10791484_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000001616 72.0
WLSH2_k127_10803508_0 Ammonium transporter K03320 - - 9.648e-221 696.0
WLSH2_k127_10803508_1 TIGRFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001666 284.0
WLSH2_k127_10803508_2 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009843 266.0
WLSH2_k127_10803508_3 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000005538 201.0
WLSH2_k127_10803508_4 Membrane fusogenic activity K09806 - - 0.0000000000000000000000000004056 117.0
WLSH2_k127_10851262_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 6.633e-271 840.0
WLSH2_k127_10851262_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 501.0
WLSH2_k127_10851262_10 Glycine zipper - - - 0.0000000000000000000000005865 107.0
WLSH2_k127_10851262_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000001035 88.0
WLSH2_k127_10851262_2 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 407.0
WLSH2_k127_10851262_3 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 381.0
WLSH2_k127_10851262_4 PFAM YicC-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 374.0
WLSH2_k127_10851262_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000204 289.0
WLSH2_k127_10851262_6 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003079 283.0
WLSH2_k127_10851262_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001093 276.0
WLSH2_k127_10851262_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000003288 227.0
WLSH2_k127_10851262_9 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000001753 189.0
WLSH2_k127_10860477_0 PFAM von Willebrand factor type A K02448 - - 1.954e-264 826.0
WLSH2_k127_10860477_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 571.0
WLSH2_k127_10860477_10 PFAM PfkB domain protein K00846 - 2.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004475 280.0
WLSH2_k127_10860477_11 TIGRFAM clan AA aspartic protease, TIGR02281 family K06985 - - 0.000000000000000000000000000000000000000000000000000000000001049 218.0
WLSH2_k127_10860477_12 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000009924 201.0
WLSH2_k127_10860477_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 427.0
WLSH2_k127_10860477_3 ABC-type Mn2 Zn2 transport systems, permease K02075,K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 408.0
WLSH2_k127_10860477_4 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 362.0
WLSH2_k127_10860477_5 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 336.0
WLSH2_k127_10860477_6 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 323.0
WLSH2_k127_10860477_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 301.0
WLSH2_k127_10860477_8 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 300.0
WLSH2_k127_10860477_9 Cobalt uptake substrate-specific transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 298.0
WLSH2_k127_10883889_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1041.0
WLSH2_k127_10883889_1 alpha beta alpha domain I K01835 - 5.4.2.2 4.585e-284 880.0
WLSH2_k127_10883889_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 571.0
WLSH2_k127_10883889_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 472.0
WLSH2_k127_10883889_4 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 343.0
WLSH2_k127_10883889_5 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
WLSH2_k127_10883889_6 - - - - 0.000000000000000000000000000000000000000000000000002854 189.0
WLSH2_k127_10883889_7 PFAM Bacterial regulatory protein, arsR family K03892 - - 0.00000000000000000000000000000000004762 138.0
WLSH2_k127_10883889_8 D12 class N6 adenine-specific DNA methyltransferase - - - 0.00000000000000000001603 93.0
WLSH2_k127_10895517_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1424.0
WLSH2_k127_10895517_1 PFAM secretion protein HlyD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 420.0
WLSH2_k127_10895517_2 Belongs to the UPF0278 family K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004394 248.0
WLSH2_k127_10895517_3 RNA ligase K07468 - 6.5.1.1 0.0000000000000000000008514 98.0
WLSH2_k127_1091099_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 498.0
WLSH2_k127_1091099_1 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 329.0
WLSH2_k127_10945805_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 529.0
WLSH2_k127_10945805_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 496.0
WLSH2_k127_10945805_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 411.0
WLSH2_k127_10945805_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 339.0
WLSH2_k127_10965006_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009521 277.0
WLSH2_k127_10965006_1 PFAM Cell wall hydrolase - - - 0.0000000000000000000000000000000000000000001361 167.0
WLSH2_k127_10965006_2 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0000000000000000000000000000000595 125.0
WLSH2_k127_10970527_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1220.0
WLSH2_k127_10970527_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.12e-311 961.0
WLSH2_k127_10970527_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 1.127e-236 748.0
WLSH2_k127_10970527_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 607.0
WLSH2_k127_10970527_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 442.0
WLSH2_k127_10970527_5 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000008211 216.0
WLSH2_k127_10970527_6 Universal stress protein K06149 - - 0.000000000000000000000000000000000004855 141.0
WLSH2_k127_10970527_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000003502 127.0
WLSH2_k127_10970527_8 - - - - 0.0000000000000004197 79.0
WLSH2_k127_11010118_0 SMART Phospholipid glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.0 1792.0
WLSH2_k127_11010118_1 UPF0313 protein - - - 0.0 1119.0
WLSH2_k127_11010118_10 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000336 136.0
WLSH2_k127_11010118_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 598.0
WLSH2_k127_11010118_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 520.0
WLSH2_k127_11010118_4 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 434.0
WLSH2_k127_11010118_5 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 376.0
WLSH2_k127_11010118_6 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 382.0
WLSH2_k127_11010118_7 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 300.0
WLSH2_k127_11010118_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
WLSH2_k127_11010118_9 Tetratricopeptide repeat K07114 - - 0.00000000000000000000000000000000000000000000001553 194.0
WLSH2_k127_11026802_0 FtsX-like permease family K02004 - - 1.381e-205 646.0
WLSH2_k127_11026802_1 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000007957 144.0
WLSH2_k127_11026802_2 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000002511 99.0
WLSH2_k127_11052593_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.613e-264 822.0
WLSH2_k127_11052593_1 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 591.0
WLSH2_k127_11052593_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 340.0
WLSH2_k127_11052593_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 286.0
WLSH2_k127_11052593_4 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000001736 226.0
WLSH2_k127_11052593_5 Belongs to the UPF0149 family K09895 - - 0.0000000000000000000000000000000000003657 148.0
WLSH2_k127_11052593_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000001995 111.0
WLSH2_k127_11052593_7 TIGRFAM TIGR02449 family protein K09892 - - 0.000000000000001908 78.0
WLSH2_k127_11105781_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.889e-211 662.0
WLSH2_k127_11105781_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 610.0
WLSH2_k127_11105781_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006284 282.0
WLSH2_k127_11105781_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000008663 192.0
WLSH2_k127_11105781_4 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000005796 190.0
WLSH2_k127_11105781_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000003445 146.0
WLSH2_k127_11129204_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1186.0
WLSH2_k127_11129204_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.101e-232 736.0
WLSH2_k127_11129204_10 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 370.0
WLSH2_k127_11129204_11 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000001044 254.0
WLSH2_k127_11129204_12 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000001486 222.0
WLSH2_k127_11129204_13 SseB protein N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000054 212.0
WLSH2_k127_11129204_14 Redoxin - - - 0.00000000000000000000000000000000000000003092 159.0
WLSH2_k127_11129204_15 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000001717 159.0
WLSH2_k127_11129204_16 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000004098 147.0
WLSH2_k127_11129204_17 Calcineurin-like phosphoesterase K03651 - 3.1.4.53 0.0000000003203 70.0
WLSH2_k127_11129204_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 603.0
WLSH2_k127_11129204_3 Stage II sporulation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 595.0
WLSH2_k127_11129204_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 587.0
WLSH2_k127_11129204_5 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 518.0
WLSH2_k127_11129204_6 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 421.0
WLSH2_k127_11129204_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 414.0
WLSH2_k127_11129204_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 406.0
WLSH2_k127_11129204_9 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 378.0
WLSH2_k127_11202442_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 1.054e-220 692.0
WLSH2_k127_11202442_1 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 431.0
WLSH2_k127_11202442_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 388.0
WLSH2_k127_11202442_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006407 258.0
WLSH2_k127_11202442_4 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000072 243.0
WLSH2_k127_11202442_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000001739 217.0
WLSH2_k127_11202442_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000002353 195.0
WLSH2_k127_11202442_7 - - - - 0.00000000000000000000000000000000000000000000000000003458 189.0
WLSH2_k127_11202442_8 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000001507 182.0
WLSH2_k127_11202442_9 - - - - 0.00001654 53.0
WLSH2_k127_11203077_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 6.028e-203 641.0
WLSH2_k127_11203077_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 454.0
WLSH2_k127_11203077_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 442.0
WLSH2_k127_11251139_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1182.0
WLSH2_k127_11251139_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1132.0
WLSH2_k127_11251139_10 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000001808 181.0
WLSH2_k127_11251139_11 SprT homologues. K02742 - - 0.000000000000000000000000000000000000000000000669 178.0
WLSH2_k127_11251139_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000004684 163.0
WLSH2_k127_11251139_13 PFAM Transposase - - - 0.0000000000000000000000000000000000001097 144.0
WLSH2_k127_11251139_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000002151 143.0
WLSH2_k127_11251139_15 PFAM Transposase - - - 0.0000000000000000006171 88.0
WLSH2_k127_11251139_16 reverse transcriptase - - - 0.00000000000000009396 94.0
WLSH2_k127_11251139_17 - - - - 0.00000000001094 67.0
WLSH2_k127_11251139_18 PFAM Transposase - - - 0.00004313 48.0
WLSH2_k127_11251139_2 Participates in both transcription termination and antitermination K02600 - - 5.573e-235 735.0
WLSH2_k127_11251139_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 5.327e-234 730.0
WLSH2_k127_11251139_4 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 - 2.3.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 561.0
WLSH2_k127_11251139_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 480.0
WLSH2_k127_11251139_6 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 477.0
WLSH2_k127_11251139_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 319.0
WLSH2_k127_11251139_8 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002901 242.0
WLSH2_k127_11251139_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000004661 196.0
WLSH2_k127_11260990_0 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 337.0
WLSH2_k127_11260990_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000000000000000000000000000003315 120.0
WLSH2_k127_11260990_2 ADP-ribosylglycohydrolase - - - 0.0000000000000000004866 91.0
WLSH2_k127_11260990_3 Sulfatase-modifying factor enzyme 1 - - - 0.000000003385 61.0
WLSH2_k127_11260990_4 Cytochrome c' K00428 - 1.11.1.5 0.0000005513 51.0
WLSH2_k127_11285502_0 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123,K18332 - 1.12.1.3,1.17.1.9 0.0 1115.0
WLSH2_k127_11285502_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.01e-316 986.0
WLSH2_k127_11285502_10 PFAM Helix-turn-helix - - - 0.000000000000000000000000000005737 121.0
WLSH2_k127_11285502_11 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000001023 84.0
WLSH2_k127_11285502_12 PFAM Transposase IS200 like K07491 - - 0.000000000004022 68.0
WLSH2_k127_11285502_13 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000001255 62.0
WLSH2_k127_11285502_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.345e-275 867.0
WLSH2_k127_11285502_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 582.0
WLSH2_k127_11285502_4 PFAM Fructosamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 399.0
WLSH2_k127_11285502_5 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000363 241.0
WLSH2_k127_11285502_6 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000004963 170.0
WLSH2_k127_11285502_7 - - - - 0.0000000000000000000000000000000000000001261 153.0
WLSH2_k127_11285502_8 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000000000000000004274 149.0
WLSH2_k127_11285502_9 Transcriptional regulator, AbiEi antitoxin - - - 0.000000000000000000000000000000002563 136.0
WLSH2_k127_11291462_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 494.0
WLSH2_k127_11291462_1 Histidine kinase K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 450.0
WLSH2_k127_11291462_2 response regulator receiver K07664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 328.0
WLSH2_k127_11291462_3 Zinc-ribbon containing domain - - - 0.000000000000000000000000000000000000000000000000000000000000008491 221.0
WLSH2_k127_11291462_4 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.000000000000000000000000000008332 119.0
WLSH2_k127_11291462_5 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000002217 104.0
WLSH2_k127_11291462_6 Protein of unknown function (DUF2281) - - - 0.000000000002792 68.0
WLSH2_k127_11291462_7 PFAM Kunitz Bovine pancreatic trypsin inhibitor domain - - - 0.00000000001005 70.0
WLSH2_k127_11301160_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 400.0
WLSH2_k127_11301160_1 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000000001039 157.0
WLSH2_k127_11301160_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000001668 128.0
WLSH2_k127_11312560_0 Succinyl-CoA ligase like flavodoxin domain - - - 0.0 1284.0
WLSH2_k127_11312560_1 ATP-dependent Clp protease, ATP-binding subunit ClpA K03694 - - 0.0 1070.0
WLSH2_k127_11312560_10 Fumarate reductase subunit C - - - 0.0000000000000000000000009501 116.0
WLSH2_k127_11312560_11 Fumarate reductase subunit D - - - 0.000000000000000000000003256 107.0
WLSH2_k127_11312560_12 aconitate hydratase K01681 - 4.2.1.3 0.0000000000000006415 79.0
WLSH2_k127_11312560_13 aconitate hydratase K01681 - 4.2.1.3 0.00000006636 55.0
WLSH2_k127_11312560_2 Fumarate reductase flavoprotein C-term - - - 1.24e-276 860.0
WLSH2_k127_11312560_3 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 3.516e-238 741.0
WLSH2_k127_11312560_4 Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) K06957 - 2.3.1.193 6.272e-212 682.0
WLSH2_k127_11312560_5 ATP citrate lyase citrate-binding - - - 4.457e-210 659.0
WLSH2_k127_11312560_6 type I secretion outer membrane protein, TolC K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 362.0
WLSH2_k127_11312560_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 347.0
WLSH2_k127_11312560_8 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000003734 169.0
WLSH2_k127_11312560_9 TIGRFAM cold shock domain protein CspD K03704 - - 0.0000000000000000000000000000009113 122.0
WLSH2_k127_11367222_0 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 552.0
WLSH2_k127_11367222_1 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
WLSH2_k127_11403932_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 4.289e-206 647.0
WLSH2_k127_11403932_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 584.0
WLSH2_k127_11403932_2 C4-dicarboxylate ABC transporter K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 491.0
WLSH2_k127_11403932_3 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
WLSH2_k127_11403932_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000001298 201.0
WLSH2_k127_11403932_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000002558 129.0
WLSH2_k127_11403932_6 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000009356 60.0
WLSH2_k127_11467830_0 DNA RNA helicase - - - 0.0 1208.0
WLSH2_k127_11467830_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000006343 87.0
WLSH2_k127_11467830_2 Sulphur globule protein - - - 0.0000000000000001038 81.0
WLSH2_k127_11479377_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 428.0
WLSH2_k127_11479377_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000577 274.0
WLSH2_k127_11479377_2 zeta toxin - - - 0.00000000000000000000000000000000000000000000000000001675 196.0
WLSH2_k127_11479377_4 RadC-like JAB domain K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0005102 43.0
WLSH2_k127_11485171_0 TerD domain K05795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 298.0
WLSH2_k127_11485171_1 stress protein K05791 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 283.0
WLSH2_k127_11485171_2 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000004285 216.0
WLSH2_k127_11485171_3 Tellurite resistance K05793 - - 0.000000000000000000000000000000000000000000000000001865 186.0
WLSH2_k127_11490402_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 572.0
WLSH2_k127_11490402_1 PFAM cobalamin (vitamin B12) biosynthesis CbiX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 292.0
WLSH2_k127_11490402_2 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000001875 154.0
WLSH2_k127_1247730_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 449.0
WLSH2_k127_1247730_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 389.0
WLSH2_k127_1247730_2 PFAM Short-chain dehydrogenase reductase SDR K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
WLSH2_k127_1247730_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 329.0
WLSH2_k127_1247730_6 - - - - 0.0000000000000000000000000007269 115.0
WLSH2_k127_1247730_7 Thioredoxin-like domain - - - 0.0000000000001181 77.0
WLSH2_k127_1269519_0 type IV pilus secretin PilQ K02666 - - 2.576e-224 717.0
WLSH2_k127_1269519_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 550.0
WLSH2_k127_1269519_10 pilus assembly protein PilP K02665 - - 0.00000000000000000000000000000000000000000127 165.0
WLSH2_k127_1269519_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 460.0
WLSH2_k127_1269519_3 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 366.0
WLSH2_k127_1269519_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006684 276.0
WLSH2_k127_1269519_5 Pilus assembly protein PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000001498 238.0
WLSH2_k127_1269519_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000565 205.0
WLSH2_k127_1269519_7 PFAM Fimbrial assembly K02663 - - 0.0000000000000000000000000000000000000000000000000001434 191.0
WLSH2_k127_1269519_8 - - - - 0.000000000000000000000000000000000000000000000000009627 188.0
WLSH2_k127_1269519_9 COG1525 Micrococcal nuclease (thermonuclease) homologs - - - 0.00000000000000000000000000000000000000000000000005361 189.0
WLSH2_k127_1289786_0 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 1.017e-259 805.0
WLSH2_k127_1289786_1 Cytochrome c K02305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001371 264.0
WLSH2_k127_1289786_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000005378 214.0
WLSH2_k127_1289786_3 PFAM Cyclic nucleotide-binding K21563 - - 0.00000000000000000000000000000000000836 139.0
WLSH2_k127_1304048_0 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 463.0
WLSH2_k127_1304048_1 TIGRFAM hemerythrin-like metal-binding K07216 - - 0.000000000000000000000000005579 116.0
WLSH2_k127_1341188_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 2.284e-310 973.0
WLSH2_k127_1341188_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 345.0
WLSH2_k127_1341188_2 Nitrate TMAO reductase, membrane-bound tetraheme cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001096 266.0
WLSH2_k127_1341188_3 Putative ATP-dependent Lon protease K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000183 207.0
WLSH2_k127_1341188_4 component of anaerobic dehydrogenases - - - 0.000000000000000000000000000000002808 139.0
WLSH2_k127_1341188_5 - - - - 0.000000000000000002941 90.0
WLSH2_k127_1356206_0 DDE_Tnp_1-associated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 424.0
WLSH2_k127_1356206_1 Transposase - - - 0.000000000000000000000000000386 115.0
WLSH2_k127_1356206_2 HTH-like domain K07497 - - 0.000000000000000003211 87.0
WLSH2_k127_1356206_3 transposase activity - - - 0.0000000002917 69.0
WLSH2_k127_1370122_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1705.0
WLSH2_k127_1370122_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.827e-243 758.0
WLSH2_k127_1370122_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 522.0
WLSH2_k127_1370122_3 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000001548 155.0
WLSH2_k127_137314_0 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 389.0
WLSH2_k127_137314_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000303 249.0
WLSH2_k127_137314_2 - - - - 0.00007729 48.0
WLSH2_k127_1417489_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.159e-220 694.0
WLSH2_k127_1417489_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 359.0
WLSH2_k127_1417489_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001114 278.0
WLSH2_k127_1417489_3 signal transduction histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001125 181.0
WLSH2_k127_1417489_4 - - - - 0.00000000000000000000000000000000000000000000002105 173.0
WLSH2_k127_1417489_5 - - - - 0.0000000000000000006709 86.0
WLSH2_k127_142786_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.858e-277 865.0
WLSH2_k127_142786_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007781 244.0
WLSH2_k127_142786_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000002118 234.0
WLSH2_k127_142786_3 Copper resistance protein D - - - 0.00000000000000000000000000000000000000001383 158.0
WLSH2_k127_142786_4 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000002625 99.0
WLSH2_k127_142786_5 - - - - 0.0000000004006 61.0
WLSH2_k127_1457093_0 Saccharopine dehydrogenase C-terminal domain K00290,K13746 - 1.5.1.43,1.5.1.7 2.433e-219 684.0
WLSH2_k127_1457093_1 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042401,GO:0042710,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044010,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044764,GO:0045312,GO:0046204,GO:0046983,GO:0048037,GO:0050662,GO:0051704,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 441.0
WLSH2_k127_1457093_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000001162 214.0
WLSH2_k127_1498500_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.888e-221 692.0
WLSH2_k127_1498500_1 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 396.0
WLSH2_k127_1498500_10 Protein of unknown function (DUF2934) - - - 0.00000001055 57.0
WLSH2_k127_1498500_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 401.0
WLSH2_k127_1498500_3 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
WLSH2_k127_1498500_4 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 345.0
WLSH2_k127_1498500_5 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 299.0
WLSH2_k127_1498500_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000136 267.0
WLSH2_k127_1498500_7 PFAM Type IV pilus assembly PilZ K02676 - - 0.00000000000000000000000000000000000000000001475 168.0
WLSH2_k127_1498500_8 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000001509 147.0
WLSH2_k127_1498500_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000006417 137.0
WLSH2_k127_151939_0 AAA domain, putative AbiEii toxin, Type IV TA system - - - 1.239e-198 630.0
WLSH2_k127_151939_1 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 460.0
WLSH2_k127_151939_2 RloB-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001826 281.0
WLSH2_k127_151939_3 sporulation resulting in formation of a cellular spore K01449 - 3.5.1.28 0.00000000000000000000002538 110.0
WLSH2_k127_151939_4 HTH-like domain K07497 - - 0.000001791 50.0
WLSH2_k127_1634421_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1100.0
WLSH2_k127_1634421_1 small GTP-binding protein K02355 - - 1.627e-291 909.0
WLSH2_k127_1634421_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000003823 119.0
WLSH2_k127_1634421_11 FUN14 family - - - 0.00000000000000000000000007758 113.0
WLSH2_k127_1634421_12 FeoA K04758 - - 0.00000000000000000006869 92.0
WLSH2_k127_1634421_13 PFAM Sporulation - - - 0.00000000000000005958 85.0
WLSH2_k127_1634421_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.641e-235 751.0
WLSH2_k127_1634421_3 Belongs to the ParA family K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 465.0
WLSH2_k127_1634421_4 PFAM ErfK YbiS YcfS YnhG family protein K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
WLSH2_k127_1634421_5 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 319.0
WLSH2_k127_1634421_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 309.0
WLSH2_k127_1634421_7 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000000000000002922 196.0
WLSH2_k127_1634421_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000005612 161.0
WLSH2_k127_1634421_9 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000000000000000149 139.0
WLSH2_k127_1664113_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000235 191.0
WLSH2_k127_1664113_1 - - - - 0.00000000000000000000000000000006708 126.0
WLSH2_k127_1664113_2 Belongs to the BolA IbaG family - - - 0.000000000004607 66.0
WLSH2_k127_1665121_0 Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 514.0
WLSH2_k127_1665121_1 metal ion transport K14445 - - 0.000000000000000000000000000000000000004214 147.0
WLSH2_k127_1665121_2 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000001324 64.0
WLSH2_k127_1678073_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1292.0
WLSH2_k127_1678073_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1220.0
WLSH2_k127_1678073_10 Protein of unknown function (DUF465) K09794 - - 0.00000000000000000000002 102.0
WLSH2_k127_1678073_2 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.406e-239 746.0
WLSH2_k127_1678073_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 545.0
WLSH2_k127_1678073_4 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 469.0
WLSH2_k127_1678073_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 388.0
WLSH2_k127_1678073_6 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 289.0
WLSH2_k127_1678073_7 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000000000000000001645 198.0
WLSH2_k127_1678073_8 Uncharacterized ACR, COG1993 - - - 0.00000000000000000000000000000000000000000000002218 171.0
WLSH2_k127_1678073_9 Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components K05785 - - 0.0000000000000000000000000000002252 130.0
WLSH2_k127_1682220_0 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 6.093e-253 787.0
WLSH2_k127_1682220_1 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 387.0
WLSH2_k127_1682220_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 0.00000000000072 68.0
WLSH2_k127_1682929_0 Transport permease protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 327.0
WLSH2_k127_1682929_1 Domain of unknown function (DUF1788) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000562 244.0
WLSH2_k127_1682929_2 Putative inner membrane protein (DUF1819) - - - 0.000000000000000000000000000000000000000000000000000000001263 206.0
WLSH2_k127_1686812_0 ATP binding N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005866 258.0
WLSH2_k127_1712779_0 GTP-binding protein TypA K06207 - - 0.0 1075.0
WLSH2_k127_1712779_1 ABC transporter, urea K11959 - - 1.274e-249 777.0
WLSH2_k127_1712779_2 Belongs to the binding-protein-dependent transport system permease family K01997,K11960 - - 6.108e-198 629.0
WLSH2_k127_1712779_3 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 582.0
WLSH2_k127_1712779_4 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 576.0
WLSH2_k127_1712779_5 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 514.0
WLSH2_k127_1712779_6 TIGRFAM urea ABC transporter, ATP-binding protein UrtD K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 442.0
WLSH2_k127_1712779_7 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 352.0
WLSH2_k127_1712779_8 - - - - 0.000000000000000000000000000000000000000000000000000001258 203.0
WLSH2_k127_1712779_9 Domain of unknown function (DUF4381) - - - 0.00000000000000000000000000000000000000000000000000802 185.0
WLSH2_k127_1713854_0 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 5e-324 1008.0
WLSH2_k127_1713854_1 arginine decarboxylase K01585 - 4.1.1.19 6.083e-210 665.0
WLSH2_k127_1713854_10 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004787 271.0
WLSH2_k127_1713854_11 Binding-protein-dependent transport system inner membrane component K02050,K15599 - - 0.000000000000000000000000000000000000000000000000000000000000000002653 236.0
WLSH2_k127_1713854_12 SH3 domain K07184 - - 0.0000000000000000000000000000000000000000000003117 179.0
WLSH2_k127_1713854_13 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000001494 160.0
WLSH2_k127_1713854_14 - - - - 0.000000000000000000000000000001389 125.0
WLSH2_k127_1713854_15 - - - - 0.000000000000000000000000001119 113.0
WLSH2_k127_1713854_16 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000002549 113.0
WLSH2_k127_1713854_17 - - - - 0.00000000000000000000000000961 114.0
WLSH2_k127_1713854_18 - - - - 0.000000000000000000989 89.0
WLSH2_k127_1713854_19 - - - - 0.000000000003837 69.0
WLSH2_k127_1713854_2 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 610.0
WLSH2_k127_1713854_3 Transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 503.0
WLSH2_k127_1713854_4 smart pdz dhr glgf - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 468.0
WLSH2_k127_1713854_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 473.0
WLSH2_k127_1713854_6 organic acid phosphorylation K00865 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 342.0
WLSH2_k127_1713854_7 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 308.0
WLSH2_k127_1713854_8 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 313.0
WLSH2_k127_1713854_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 293.0
WLSH2_k127_1720939_0 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 315.0
WLSH2_k127_1720939_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006858 244.0
WLSH2_k127_1744157_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1259.0
WLSH2_k127_1744157_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 437.0
WLSH2_k127_1744157_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 415.0
WLSH2_k127_1744157_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 368.0
WLSH2_k127_1744157_4 PFAM Peptidoglycan-binding lysin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002727 278.0
WLSH2_k127_1744157_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000001226 265.0
WLSH2_k127_1744157_6 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000005879 245.0
WLSH2_k127_1744157_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000001409 234.0
WLSH2_k127_1768128_0 PFAM glycosyl transferase family 39 - - - 4.465e-203 648.0
WLSH2_k127_1768128_1 Type II secretory pathway component ExeA K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 593.0
WLSH2_k127_1768128_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 502.0
WLSH2_k127_1768128_3 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 348.0
WLSH2_k127_1768128_4 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000009719 258.0
WLSH2_k127_1768128_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003165 249.0
WLSH2_k127_1768128_6 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000002313 244.0
WLSH2_k127_1768128_7 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000187 197.0
WLSH2_k127_1768128_8 Type II secretion system protein B K02451 - - 0.0000000000000001567 81.0
WLSH2_k127_1804705_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 7.513e-309 971.0
WLSH2_k127_1804705_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 533.0
WLSH2_k127_1804705_10 overlaps another CDS with the same product name - - - 0.0007178 45.0
WLSH2_k127_1804705_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 510.0
WLSH2_k127_1804705_3 PFAM Uncharacterised protein family UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 412.0
WLSH2_k127_1804705_4 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 378.0
WLSH2_k127_1804705_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 368.0
WLSH2_k127_1804705_6 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003297 260.0
WLSH2_k127_1804705_7 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003443 259.0
WLSH2_k127_1804705_8 Protein of unknown function (DUF1016) - - - 0.000000009088 59.0
WLSH2_k127_1804705_9 PFAM integrase - - - 0.000003876 52.0
WLSH2_k127_1918195_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1464.0
WLSH2_k127_1918195_1 Na H antiporter K05559 - - 0.0 1251.0
WLSH2_k127_1918195_10 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
WLSH2_k127_1918195_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
WLSH2_k127_1918195_12 Na+/H+ ion antiporter subunit K05562 - - 0.000000000000000000000000000000000000000000000000000004778 201.0
WLSH2_k127_1918195_13 Protein of unknown function (DUF3775) - - - 0.000000000000000000000000000000000000000000000002528 176.0
WLSH2_k127_1918195_14 oxidoreductase, chain 4L K05560 - - 0.000000000000000000000000000000000000000000009889 169.0
WLSH2_k127_1918195_15 HicB family - - - 0.0000000000000000000000000000000000000000005058 162.0
WLSH2_k127_1918195_16 PFAM Na H antiporter subunit K05564 - - 0.0000000000000000000000000000000000000005243 150.0
WLSH2_k127_1918195_17 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000000000002387 148.0
WLSH2_k127_1918195_18 Protein of unknown function (DUF454) K09790 - - 0.00000000000000000000000000000000002344 141.0
WLSH2_k127_1918195_19 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05563 - - 0.00000000000000000000000000000001508 132.0
WLSH2_k127_1918195_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.259e-220 691.0
WLSH2_k127_1918195_20 Belongs to the PsiE family K13256 - - 0.00000000000000000000000000000002745 131.0
WLSH2_k127_1918195_21 - - - - 0.00000000000000000000000000000007645 129.0
WLSH2_k127_1918195_22 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000001148 119.0
WLSH2_k127_1918195_23 Sigma 54 modulation protein S30EA ribosomal protein - - - 0.0000000000000000000001454 106.0
WLSH2_k127_1918195_24 - - - - 0.000000008071 56.0
WLSH2_k127_1918195_25 - - - - 0.000002471 56.0
WLSH2_k127_1918195_26 - - - - 0.0009869 44.0
WLSH2_k127_1918195_3 PFAM NADH Ubiquinone plastoquinone K05561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 595.0
WLSH2_k127_1918195_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 495.0
WLSH2_k127_1918195_5 Alcohol dehydrogenase GroES-like domain K00001,K19745 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 482.0
WLSH2_k127_1918195_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 401.0
WLSH2_k127_1918195_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 375.0
WLSH2_k127_1918195_8 PFAM Cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 352.0
WLSH2_k127_1918195_9 Polycystin cation channel K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 349.0
WLSH2_k127_1971469_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 591.0
WLSH2_k127_1971469_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 567.0
WLSH2_k127_1971469_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 312.0
WLSH2_k127_1971469_3 Putative DNA-binding domain K03655 - 3.6.4.12 0.0000000000000000000000000000003005 129.0
WLSH2_k127_1971469_4 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000163 117.0
WLSH2_k127_1971469_5 - K03655 - 3.6.4.12 0.00000000000000000000000004501 115.0
WLSH2_k127_1971469_6 COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related K01153 - 3.1.21.3 0.0000000000000001142 83.0
WLSH2_k127_2012369_0 protein conserved in bacteria - - - 0.0 1767.0
WLSH2_k127_2012369_1 Protein of unknown function (DUF3375) - - - 1.866e-256 797.0
WLSH2_k127_2012369_2 Protein of unknown function, DUF255 K06888 - - 3.215e-211 675.0
WLSH2_k127_2012369_3 Uncharacterized protein conserved in bacteria N-term (DUF3322) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 512.0
WLSH2_k127_2012369_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 388.0
WLSH2_k127_2012369_5 Domain of unknown function (DUF4194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 288.0
WLSH2_k127_2012369_6 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000001559 153.0
WLSH2_k127_2112268_0 PFAM Glycosyl transferase family 2 - - - 0.0 1382.0
WLSH2_k127_2112268_1 Polyphosphate AMP phosphotransferase - - - 1.794e-244 766.0
WLSH2_k127_2112268_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 555.0
WLSH2_k127_2112268_3 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 474.0
WLSH2_k127_2112268_4 PFAM thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000001066 181.0
WLSH2_k127_2112268_5 - - - - 0.00000000000000000000000000000000004182 148.0
WLSH2_k127_2112268_6 Regulatory protein, FmdB family - - - 0.000000000000000000000000000000000505 134.0
WLSH2_k127_2112268_7 - - - - 0.00000001679 66.0
WLSH2_k127_217383_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.695e-242 752.0
WLSH2_k127_217383_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 563.0
WLSH2_k127_217383_2 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 432.0
WLSH2_k127_217383_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002538 289.0
WLSH2_k127_217383_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01175 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0016790,GO:0044424,GO:0044444,GO:0044464,GO:0052689 - 0.0000000000000000000000000000002426 128.0
WLSH2_k127_217383_5 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000003071 100.0
WLSH2_k127_217383_6 - - - - 0.00000000000003127 76.0
WLSH2_k127_217383_7 Universal stress protein family K07090 - - 0.000000002906 61.0
WLSH2_k127_2174654_0 Fic/DOC family - - - 1.119e-245 766.0
WLSH2_k127_2174654_1 Transposase IS4 family - - - 0.0000000000000000000000000000000000000000000000000000000000002826 213.0
WLSH2_k127_2174654_2 Transposase IS4 family - - - 0.000000000000000000000000000000000000000000000000000003829 192.0
WLSH2_k127_2174654_3 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000005124 162.0
WLSH2_k127_2174654_4 Transposase IS4 family - - - 0.0000000000000000000000000000002158 123.0
WLSH2_k127_2174654_5 transposase activity - - - 0.0000000000000000304 81.0
WLSH2_k127_2174654_6 transposase activity - - - 0.00000000002762 68.0
WLSH2_k127_2174654_7 Helix-turn-helix domain - - - 0.0000002493 52.0
WLSH2_k127_2174654_8 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000003942 55.0
WLSH2_k127_2253511_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1776.0
WLSH2_k127_2253511_1 Dynamin family - - - 1.154e-194 638.0
WLSH2_k127_2253511_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 516.0
WLSH2_k127_2253511_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 528.0
WLSH2_k127_2253511_4 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.8.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 409.0
WLSH2_k127_2253511_5 PFAM Ankyrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 324.0
WLSH2_k127_2253511_6 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001532 259.0
WLSH2_k127_2253511_7 PFAM Cytochrome C K17230 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000003011 215.0
WLSH2_k127_2253511_8 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000008002 54.0
WLSH2_k127_2257762_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 381.0
WLSH2_k127_2257762_1 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 363.0
WLSH2_k127_2257762_2 membrane protein, TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 342.0
WLSH2_k127_2257762_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000000000000000001139 239.0
WLSH2_k127_2257762_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000522 205.0
WLSH2_k127_2257762_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000007997 82.0
WLSH2_k127_2271155_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1508.0
WLSH2_k127_2271155_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.869e-231 726.0
WLSH2_k127_2271155_10 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 480.0
WLSH2_k127_2271155_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 473.0
WLSH2_k127_2271155_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 448.0
WLSH2_k127_2271155_13 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 395.0
WLSH2_k127_2271155_14 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 391.0
WLSH2_k127_2271155_15 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003368 244.0
WLSH2_k127_2271155_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000000000002214 214.0
WLSH2_k127_2271155_17 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000000000000000005986 189.0
WLSH2_k127_2271155_18 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000007974 94.0
WLSH2_k127_2271155_19 Protein of unknown function (DUF721) - - - 0.0000000000000004617 83.0
WLSH2_k127_2271155_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.532e-221 693.0
WLSH2_k127_2271155_20 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000003248 52.0
WLSH2_k127_2271155_3 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 5.682e-218 692.0
WLSH2_k127_2271155_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 591.0
WLSH2_k127_2271155_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 596.0
WLSH2_k127_2271155_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 547.0
WLSH2_k127_2271155_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 531.0
WLSH2_k127_2271155_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 530.0
WLSH2_k127_2271155_9 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 494.0
WLSH2_k127_2276928_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 3.799e-272 851.0
WLSH2_k127_2276928_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 540.0
WLSH2_k127_2276928_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 388.0
WLSH2_k127_2276928_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 353.0
WLSH2_k127_2276928_4 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 306.0
WLSH2_k127_2276928_5 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000001688 157.0
WLSH2_k127_2276928_6 Belongs to the UPF0434 family K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000001351 112.0
WLSH2_k127_2276928_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000339 65.0
WLSH2_k127_2524855_0 Periplasmic copper-binding protein (NosD) K07218 - - 9.755e-194 621.0
WLSH2_k127_2524855_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 512.0
WLSH2_k127_2524855_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 515.0
WLSH2_k127_2524855_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 398.0
WLSH2_k127_2524855_4 Pfam cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 340.0
WLSH2_k127_2524855_5 abc transporter atp-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 315.0
WLSH2_k127_2524855_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000001977 147.0
WLSH2_k127_2529124_0 protein methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 397.0
WLSH2_k127_2529124_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 289.0
WLSH2_k127_2538026_0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 6.003e-235 747.0
WLSH2_k127_2538026_1 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 328.0
WLSH2_k127_2538026_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000287 237.0
WLSH2_k127_2538026_3 Glycosyl transferase, family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000003977 224.0
WLSH2_k127_2538026_4 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000001566 160.0
WLSH2_k127_2538026_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000009853 61.0
WLSH2_k127_2540430_0 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 502.0
WLSH2_k127_2540430_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004306 274.0
WLSH2_k127_2540430_2 - - - - 0.000000000000000000000000000000000000000000000000000001071 197.0
WLSH2_k127_2540430_3 - - - - 0.0000000000000000000000001508 111.0
WLSH2_k127_2565254_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.557e-267 829.0
WLSH2_k127_2565254_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.743e-255 792.0
WLSH2_k127_2565254_10 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 400.0
WLSH2_k127_2565254_11 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 394.0
WLSH2_k127_2565254_12 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 362.0
WLSH2_k127_2565254_13 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000002442 226.0
WLSH2_k127_2565254_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000001659 201.0
WLSH2_k127_2565254_15 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000002531 177.0
WLSH2_k127_2565254_16 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000003678 183.0
WLSH2_k127_2565254_17 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000000000000008812 161.0
WLSH2_k127_2565254_18 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000005545 130.0
WLSH2_k127_2565254_19 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000197 114.0
WLSH2_k127_2565254_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 9.986e-254 804.0
WLSH2_k127_2565254_20 PFAM VanZ - - - 0.000000000000000000009287 98.0
WLSH2_k127_2565254_21 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.00000000000000000007335 93.0
WLSH2_k127_2565254_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.75e-236 735.0
WLSH2_k127_2565254_4 Belongs to the GARS family K01945 - 6.3.4.13 6.56e-213 668.0
WLSH2_k127_2565254_5 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 3.717e-209 679.0
WLSH2_k127_2565254_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 531.0
WLSH2_k127_2565254_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 442.0
WLSH2_k127_2565254_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 438.0
WLSH2_k127_2565254_9 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 422.0
WLSH2_k127_2573502_0 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 463.0
WLSH2_k127_2573502_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 434.0
WLSH2_k127_2573502_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 379.0
WLSH2_k127_2573502_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000007448 53.0
WLSH2_k127_2605553_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 397.0
WLSH2_k127_2605553_1 Hydrophobe Amphiphile Efflux-1 (HAE1) K03296,K18138 - - 0.00000000000000000000000000001105 118.0
WLSH2_k127_2605553_2 (twin-arginine translocation) pathway signal - - - 0.0000001994 54.0
WLSH2_k127_2607208_0 alpha beta alpha domain I K01840 - 5.4.2.8 4.217e-210 663.0
WLSH2_k127_2637353_0 PFAM Pyruvate carboxyltransferase K01666 - 4.1.3.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 589.0
WLSH2_k127_2637353_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000000000000000000000000000000000000000000001638 180.0
WLSH2_k127_2637353_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000002397 63.0
WLSH2_k127_2643679_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.647e-216 681.0
WLSH2_k127_2643679_1 COG0147 Anthranilate para-aminobenzoate synthases component I K01665 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 318.0
WLSH2_k127_2646684_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1748.0
WLSH2_k127_2646684_1 Malic enzyme K00029 - 1.1.1.40 0.0 1290.0
WLSH2_k127_2646684_10 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000000000000000009608 191.0
WLSH2_k127_2646684_11 - - - - 0.00000000000000000000000000000000000000000000005206 170.0
WLSH2_k127_2646684_12 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000000000000000000000008689 154.0
WLSH2_k127_2646684_13 belongs to the aldehyde dehydrogenase family K00135 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006553,GO:0006554,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019477,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046440,GO:0047949,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000008442 98.0
WLSH2_k127_2646684_14 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00004337 46.0
WLSH2_k127_2646684_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.643e-224 703.0
WLSH2_k127_2646684_3 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.639e-197 621.0
WLSH2_k127_2646684_4 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 549.0
WLSH2_k127_2646684_5 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 510.0
WLSH2_k127_2646684_6 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 432.0
WLSH2_k127_2646684_7 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 384.0
WLSH2_k127_2646684_8 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002866 243.0
WLSH2_k127_2646684_9 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000002005 210.0
WLSH2_k127_2671330_0 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 448.0
WLSH2_k127_2671330_1 PFAM helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 387.0
WLSH2_k127_2671330_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 377.0
WLSH2_k127_2671330_3 amidase activity - - - 0.00000002001 59.0
WLSH2_k127_2671823_0 signal transduction histidine kinase - - - 1.245e-300 941.0
WLSH2_k127_2671823_1 response regulator receiver K13599 - - 4.029e-252 783.0
WLSH2_k127_2671823_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.86e-237 741.0
WLSH2_k127_2671823_3 PFAM TrkA-N domain K03499 - - 2.266e-220 691.0
WLSH2_k127_2671823_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 496.0
WLSH2_k127_2714025_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 469.0
WLSH2_k127_2714025_1 - - - - 0.00000000000000000000000005368 113.0
WLSH2_k127_2714025_2 - - - - 0.0000000000000000001398 94.0
WLSH2_k127_2714025_3 PFAM DNA polymerase, beta domain protein region - - - 0.0005155 46.0
WLSH2_k127_2734209_0 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 544.0
WLSH2_k127_2734209_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 437.0
WLSH2_k127_2734209_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000006668 253.0
WLSH2_k127_275214_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 4.662e-216 678.0
WLSH2_k127_275214_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001252 272.0
WLSH2_k127_275214_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000001078 180.0
WLSH2_k127_2767965_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 2.048e-222 699.0
WLSH2_k127_2767965_1 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.156e-214 675.0
WLSH2_k127_2767965_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 301.0
WLSH2_k127_2767965_3 PFAM Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001796 235.0
WLSH2_k127_2767965_4 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000004327 200.0
WLSH2_k127_2771997_0 'Kef-type K transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 385.0
WLSH2_k127_2771997_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000001411 165.0
WLSH2_k127_2771997_2 Putative transposase, YhgA-like - - - 0.0000000000000000006171 88.0
WLSH2_k127_288138_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 417.0
WLSH2_k127_288138_1 Cytochrome c-type biogenesis protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 325.0
WLSH2_k127_288138_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000007189 216.0
WLSH2_k127_288138_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000000002273 76.0
WLSH2_k127_2911395_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K00595 - 2.1.1.132 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 523.0
WLSH2_k127_2911395_1 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 519.0
WLSH2_k127_2911395_10 Cobalamin synthesis G N-terminal K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 323.0
WLSH2_k127_2911395_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 495.0
WLSH2_k127_2911395_3 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 461.0
WLSH2_k127_2911395_4 PFAM aminotransferase, class I K02225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 422.0
WLSH2_k127_2911395_5 Belongs to the precorrin methyltransferase family K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 394.0
WLSH2_k127_2911395_6 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 387.0
WLSH2_k127_2911395_7 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 377.0
WLSH2_k127_2911395_8 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 337.0
WLSH2_k127_2911395_9 Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 314.0
WLSH2_k127_2953113_0 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 364.0
WLSH2_k127_2953113_1 HlyD family secretion protein - - - 0.0000000000000000000473 94.0
WLSH2_k127_2958033_0 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 427.0
WLSH2_k127_2958033_1 FAD dependent oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 347.0
WLSH2_k127_2958033_2 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 317.0
WLSH2_k127_2980977_0 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 412.0
WLSH2_k127_2980977_1 Toxin with endonuclease activity, of toxin-antitoxin system K19155 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0030308,GO:0034641,GO:0040008,GO:0043021,GO:0043023,GO:0043170,GO:0044237,GO:0044238,GO:0044877,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008495 250.0
WLSH2_k127_2980977_2 PFAM Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000001591 162.0
WLSH2_k127_2980977_3 prlF antitoxin for toxin YhaV_toxin - - - 0.00000000000000000000000000000000000000003507 154.0
WLSH2_k127_2980977_4 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.00000000003915 67.0
WLSH2_k127_2987227_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.078e-272 844.0
WLSH2_k127_2987227_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 480.0
WLSH2_k127_2987227_2 Colicin V production protein K03558 - - 0.00000005061 55.0
WLSH2_k127_3001610_0 COG0501 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 502.0
WLSH2_k127_3001610_1 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003636 265.0
WLSH2_k127_3001610_2 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000003747 176.0
WLSH2_k127_3001610_3 SMART zinc finger CDGSH-type domain protein - - - 0.000000000000000000000000004251 118.0
WLSH2_k127_3033188_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K07309,K07310,K07811,K07812,K08351 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009033,GO:0009055,GO:0009060,GO:0009061,GO:0009322,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016657,GO:0016661,GO:0016662,GO:0016667,GO:0016671,GO:0022900,GO:0030151,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0032991,GO:0033744,GO:0033797,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0050626,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.7.2.3,1.8.5.3,1.97.1.9 0.0 1462.0
WLSH2_k127_3033188_1 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.0 1159.0
WLSH2_k127_3033188_10 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000002793 190.0
WLSH2_k127_3033188_11 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000005087 183.0
WLSH2_k127_3033188_12 - - - - 0.0000000000000000000000000000000000000000000000006849 178.0
WLSH2_k127_3033188_13 - - - - 0.0000000000000000000000000000000000002101 156.0
WLSH2_k127_3033188_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001971 132.0
WLSH2_k127_3033188_15 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000001183 125.0
WLSH2_k127_3033188_16 - - - - 0.00000000000000000000000003011 114.0
WLSH2_k127_3033188_17 Cytochrome c - - - 0.0000000000000000000000001056 109.0
WLSH2_k127_3033188_2 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 556.0
WLSH2_k127_3033188_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 542.0
WLSH2_k127_3033188_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 424.0
WLSH2_k127_3033188_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 379.0
WLSH2_k127_3033188_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 317.0
WLSH2_k127_3033188_7 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000029 286.0
WLSH2_k127_3033188_8 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001276 268.0
WLSH2_k127_3033188_9 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000000000000009684 199.0
WLSH2_k127_3061369_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 6.615e-300 929.0
WLSH2_k127_3061369_1 Belongs to the alpha-IPM synthase homocitrate synthase family K09011 - 2.3.1.182 2.714e-258 809.0
WLSH2_k127_3061369_2 TIGRFAM Threonine synthase K01733 - 4.2.3.1 2.113e-218 688.0
WLSH2_k127_3061369_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.229e-198 626.0
WLSH2_k127_3061369_4 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 317.0
WLSH2_k127_3061369_5 solute sodium symporter, small subunit - - - 0.00000000000000000000000000000000002796 138.0
WLSH2_k127_3083788_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.824e-246 762.0
WLSH2_k127_3083788_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 501.0
WLSH2_k127_3083788_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003051 270.0
WLSH2_k127_3083788_3 Protein of unknown function (DUF1640) - - - 0.00000000000000000000000000000007592 125.0
WLSH2_k127_3093044_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0 1072.0
WLSH2_k127_3093044_1 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 441.0
WLSH2_k127_3093044_2 Polycystin cation channel K08714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 369.0
WLSH2_k127_3093044_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000001265 128.0
WLSH2_k127_3093044_4 membrane protein, terc - - - 0.00000000001258 67.0
WLSH2_k127_3101366_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 449.0
WLSH2_k127_3101366_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 322.0
WLSH2_k127_3101366_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001921 283.0
WLSH2_k127_3101366_3 - - - - 0.000000000000000000000000000000000000000001211 160.0
WLSH2_k127_3113370_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1275.0
WLSH2_k127_3113370_1 TonB-dependent Receptor Plug Domain K02014 - - 1.013e-302 945.0
WLSH2_k127_3113370_10 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000009232 201.0
WLSH2_k127_3113370_11 COG4567 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.00000000000000000000000000000000000000000000000000217 190.0
WLSH2_k127_3113370_12 transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000003346 166.0
WLSH2_k127_3113370_13 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000008571 164.0
WLSH2_k127_3113370_14 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000008231 152.0
WLSH2_k127_3113370_15 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000001416 138.0
WLSH2_k127_3113370_16 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000588 134.0
WLSH2_k127_3113370_17 Protein of unknown function (DUF3240) - - - 0.00000000000000000000000000009539 119.0
WLSH2_k127_3113370_18 - - - - 0.0000000003152 63.0
WLSH2_k127_3113370_19 NosL - - - 0.000000008543 56.0
WLSH2_k127_3113370_2 Domain of unknown function (DUF1705) K03760 - 2.7.8.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 508.0
WLSH2_k127_3113370_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 436.0
WLSH2_k127_3113370_4 His Kinase A (phosphoacceptor) domain K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 447.0
WLSH2_k127_3113370_5 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 429.0
WLSH2_k127_3113370_6 Transcriptional regulatory protein, C terminal K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
WLSH2_k127_3113370_7 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001652 284.0
WLSH2_k127_3113370_8 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000001253 226.0
WLSH2_k127_3113370_9 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000002958 224.0
WLSH2_k127_3125530_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 395.0
WLSH2_k127_3125530_1 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 380.0
WLSH2_k127_3125530_2 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 302.0
WLSH2_k127_3125530_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004741 272.0
WLSH2_k127_3125530_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000001092 120.0
WLSH2_k127_3125530_6 Protein of unknown function, DUF484 K09921 - - 0.00000000000002618 74.0
WLSH2_k127_3144589_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1081.0
WLSH2_k127_3144589_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.02e-214 672.0
WLSH2_k127_3144589_2 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 588.0
WLSH2_k127_3144589_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 368.0
WLSH2_k127_3144589_4 Cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000007751 188.0
WLSH2_k127_3159094_0 Heat shock 70 kDa protein K04043 - - 0.0 1081.0
WLSH2_k127_3159094_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 2.999e-248 769.0
WLSH2_k127_3159094_10 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 333.0
WLSH2_k127_3159094_11 PFAM NapC NirT cytochrome c K03532 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
WLSH2_k127_3159094_12 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000006598 273.0
WLSH2_k127_3159094_13 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000004132 214.0
WLSH2_k127_3159094_14 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000004451 220.0
WLSH2_k127_3159094_15 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000007439 215.0
WLSH2_k127_3159094_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000000000000000000000000589 195.0
WLSH2_k127_3159094_17 - - - - 0.0000000000000000000000000000000000000000000000002783 184.0
WLSH2_k127_3159094_18 protein conserved in bacteria K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000003018 152.0
WLSH2_k127_3159094_2 Seven times multi-haem cytochrome CxxCH K10535 - 1.7.2.6 1.549e-247 772.0
WLSH2_k127_3159094_3 May be involved in recombinational repair of damaged DNA K03631 - - 2.893e-207 660.0
WLSH2_k127_3159094_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.869e-197 619.0
WLSH2_k127_3159094_5 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 567.0
WLSH2_k127_3159094_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 473.0
WLSH2_k127_3159094_7 pfam php K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 381.0
WLSH2_k127_3159094_8 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 358.0
WLSH2_k127_3159094_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 351.0
WLSH2_k127_3178492_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1334.0
WLSH2_k127_3178492_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 6.653e-220 686.0
WLSH2_k127_3178492_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000001022 164.0
WLSH2_k127_3178492_3 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000003735 149.0
WLSH2_k127_3178492_4 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000000000000001144 112.0
WLSH2_k127_3178492_6 Helix-turn-helix XRE-family like proteins - - - 0.0003982 46.0
WLSH2_k127_32044_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 603.0
WLSH2_k127_32044_1 PFAM nucleoside H symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 483.0
WLSH2_k127_32044_2 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 289.0
WLSH2_k127_3221879_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1394.0
WLSH2_k127_3221879_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1192.0
WLSH2_k127_3221879_10 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 5.196e-204 643.0
WLSH2_k127_3221879_11 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 1.138e-201 631.0
WLSH2_k127_3221879_12 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 591.0
WLSH2_k127_3221879_13 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006671 554.0
WLSH2_k127_3221879_14 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 511.0
WLSH2_k127_3221879_15 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 505.0
WLSH2_k127_3221879_16 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 437.0
WLSH2_k127_3221879_17 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 428.0
WLSH2_k127_3221879_18 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 415.0
WLSH2_k127_3221879_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 344.0
WLSH2_k127_3221879_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.117e-280 863.0
WLSH2_k127_3221879_20 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 320.0
WLSH2_k127_3221879_21 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 311.0
WLSH2_k127_3221879_22 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 313.0
WLSH2_k127_3221879_23 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 300.0
WLSH2_k127_3221879_24 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 287.0
WLSH2_k127_3221879_25 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000098 283.0
WLSH2_k127_3221879_26 (sprot CYCP_CHRVI). CYTOCHROME C IS THE MOST WIDELY OCCURRING BACTERIAL C-TYPE CYTOCHROME. CYTOCHROMES C ARE HIGH-SPIN PROTEINS AND THE HEME HAS NO SIXTH LIGAND. THEIR EXACT FUNCTION IS NOT KNOWN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004727 245.0
WLSH2_k127_3221879_27 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000002173 224.0
WLSH2_k127_3221879_28 PFAM Ankyrin - - - 0.0000000000000000000000000000000000000000000008581 180.0
WLSH2_k127_3221879_29 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000000000000005569 136.0
WLSH2_k127_3221879_3 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.022e-247 785.0
WLSH2_k127_3221879_30 Thioesterase superfamily K02614 - - 0.00000000000000000000000000007888 123.0
WLSH2_k127_3221879_31 - - - - 0.00000000000002024 86.0
WLSH2_k127_3221879_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.401e-236 739.0
WLSH2_k127_3221879_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.802e-222 710.0
WLSH2_k127_3221879_6 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 6.882e-209 653.0
WLSH2_k127_3221879_7 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.695e-208 651.0
WLSH2_k127_3221879_8 Phosphoglycerate kinase K00927 - 2.7.2.3 4.522e-205 647.0
WLSH2_k127_3221879_9 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 4.15e-204 636.0
WLSH2_k127_3221940_0 Ryanodine receptor Ryr - - - 7.288e-245 769.0
WLSH2_k127_3221940_1 Amp-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 598.0
WLSH2_k127_3221940_10 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000001325 159.0
WLSH2_k127_3221940_11 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000002923 109.0
WLSH2_k127_3221940_12 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000008366 75.0
WLSH2_k127_3221940_13 OsmC-like protein - - - 0.0000000004321 62.0
WLSH2_k127_3221940_14 Putative MetA-pathway of phenol degradation - - - 0.00003186 46.0
WLSH2_k127_3221940_2 Histidine kinase K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 437.0
WLSH2_k127_3221940_3 response regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 367.0
WLSH2_k127_3221940_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 344.0
WLSH2_k127_3221940_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
WLSH2_k127_3221940_6 Nadh flavin oxidoreductase nadh oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002059 279.0
WLSH2_k127_3221940_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004003 278.0
WLSH2_k127_3221940_8 Long-chain fatty acid--CoA ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000269 225.0
WLSH2_k127_3221940_9 Thermostable hemolysin - - - 0.00000000000000000000000000000000000000000000000000000000000003115 220.0
WLSH2_k127_3231215_0 Polysaccharide biosynthesis protein - - - 2.105e-258 811.0
WLSH2_k127_3231215_1 PFAM Type II secretion system protein E K02454 - - 5.253e-209 671.0
WLSH2_k127_3231215_10 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000003224 231.0
WLSH2_k127_3231215_11 PFAM Rhodanese-like - - - 0.000000000000000000000000000000000000000000000000000000000000002885 219.0
WLSH2_k127_3231215_12 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
WLSH2_k127_3231215_13 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000003179 179.0
WLSH2_k127_3231215_14 - - - - 0.00000000000000000000000000005513 118.0
WLSH2_k127_3231215_2 Type II secretion system K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 552.0
WLSH2_k127_3231215_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 556.0
WLSH2_k127_3231215_4 Belongs to the dihydroorotate dehydrogenase family K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 540.0
WLSH2_k127_3231215_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 438.0
WLSH2_k127_3231215_6 PFAM Glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 368.0
WLSH2_k127_3231215_7 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 332.0
WLSH2_k127_3231215_8 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 315.0
WLSH2_k127_3231215_9 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000002184 233.0
WLSH2_k127_3231382_0 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 415.0
WLSH2_k127_3231382_1 PFAM Cyclic nucleotide-binding K21563 - - 0.000000000000000000000000000000000000000000000000000000000000003519 220.0
WLSH2_k127_3279373_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1371.0
WLSH2_k127_3279373_1 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000000000000001886 245.0
WLSH2_k127_3279373_2 - - - - 0.00000000000000000000001429 107.0
WLSH2_k127_3279373_3 - - - - 0.000000000000001006 86.0
WLSH2_k127_3305879_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1620.0
WLSH2_k127_3305879_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1137.0
WLSH2_k127_3305879_10 Helix-turn-helix domain - - - 0.0000000000000000000000001088 108.0
WLSH2_k127_3305879_2 alpha beta hydrolase fold K03821 - - 4.579e-236 746.0
WLSH2_k127_3305879_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 504.0
WLSH2_k127_3305879_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 343.0
WLSH2_k127_3305879_5 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 286.0
WLSH2_k127_3305879_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001496 273.0
WLSH2_k127_3305879_7 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001833 255.0
WLSH2_k127_3305879_8 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000006996 232.0
WLSH2_k127_3305879_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000001867 170.0
WLSH2_k127_3353995_0 PFAM thiamine pyrophosphate enzyme K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007608 451.0
WLSH2_k127_3353995_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000003706 178.0
WLSH2_k127_3353995_2 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000001309 105.0
WLSH2_k127_3364340_0 Histidine kinase - - - 1.696e-280 882.0
WLSH2_k127_3364340_1 Pyrimidine nucleoside phosphorylase C-terminal domain K00758 - 2.4.2.4 1.223e-236 747.0
WLSH2_k127_3364340_10 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000007075 156.0
WLSH2_k127_3364340_2 amino acid carrier protein K03310 - - 7.023e-212 666.0
WLSH2_k127_3364340_3 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 469.0
WLSH2_k127_3364340_4 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 465.0
WLSH2_k127_3364340_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 398.0
WLSH2_k127_3364340_6 response regulator receiver K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 331.0
WLSH2_k127_3364340_7 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000009323 244.0
WLSH2_k127_3364340_8 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000000000000002126 198.0
WLSH2_k127_3364340_9 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000005382 160.0
WLSH2_k127_3383341_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 516.0
WLSH2_k127_3383341_1 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 313.0
WLSH2_k127_3418552_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 511.0
WLSH2_k127_3418552_1 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 424.0
WLSH2_k127_3418552_2 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 351.0
WLSH2_k127_3418552_3 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 320.0
WLSH2_k127_3418552_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000000000000001002 235.0
WLSH2_k127_3418552_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000000000000000002652 228.0
WLSH2_k127_3418552_6 periplasmic protein - - - 0.0000000000000000000000000000000000000000000000000000008995 203.0
WLSH2_k127_3418552_7 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000006889 171.0
WLSH2_k127_3418552_8 Citrate transporter - - - 0.0000000000000000000000000000000000000061 148.0
WLSH2_k127_3439998_0 Hydrophobe Amphiphile Efflux-1 (HAE1) K03296,K18138 - - 0.0 1291.0
WLSH2_k127_3439998_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 467.0
WLSH2_k127_3439998_2 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 362.0
WLSH2_k127_3439998_3 lipid catabolic process - - - 0.0000000000000000000000000000000002866 145.0
WLSH2_k127_3439998_4 - - - - 0.0000000000000000001741 92.0
WLSH2_k127_3440790_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1984.0
WLSH2_k127_3440790_1 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 1.093e-279 882.0
WLSH2_k127_3440790_2 Sulfate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 567.0
WLSH2_k127_3440790_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 477.0
WLSH2_k127_3440790_4 PFAM ATP dependent DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 391.0
WLSH2_k127_3440790_5 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 297.0
WLSH2_k127_3440790_6 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000003584 208.0
WLSH2_k127_3440790_7 CRS1_YhbY K07574 - - 0.0000000000000000000000000000000000004194 144.0
WLSH2_k127_3440790_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000931 46.0
WLSH2_k127_3440790_9 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.0007567 47.0
WLSH2_k127_3443898_0 PFAM ABC transporter K06158 - - 1.252e-255 798.0
WLSH2_k127_3443898_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 2.421e-234 734.0
WLSH2_k127_3443898_2 Membrane fusogenic activity K09806 - - 0.000000000000001682 77.0
WLSH2_k127_3462003_0 Thiosulfate-oxidizing multienzyme system protein SoxA K17222,K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 393.0
WLSH2_k127_3462003_1 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005455 259.0
WLSH2_k127_3514556_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 2.274e-228 734.0
WLSH2_k127_3514556_1 Belongs to the UPF0061 (SELO) family - - - 3.958e-198 625.0
WLSH2_k127_3514556_2 Sulphur globule protein - - - 0.0000000000000000000000000000000000000000004276 160.0
WLSH2_k127_3559748_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.017e-247 767.0
WLSH2_k127_3559748_1 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 8.993e-238 743.0
WLSH2_k127_3559748_10 - - - - 0.0000000001437 66.0
WLSH2_k127_3559748_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.963e-233 728.0
WLSH2_k127_3559748_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 8.255e-199 624.0
WLSH2_k127_3559748_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 521.0
WLSH2_k127_3559748_5 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 302.0
WLSH2_k127_3559748_6 pfam nudix K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000000001576 197.0
WLSH2_k127_3559748_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000002338 196.0
WLSH2_k127_3559748_8 - - - - 0.0000000000000000000000000000000006853 134.0
WLSH2_k127_3559748_9 - - - - 0.000000000000000000000002182 105.0
WLSH2_k127_3623798_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 366.0
WLSH2_k127_3623798_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000003581 134.0
WLSH2_k127_3623798_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000003769 57.0
WLSH2_k127_3625268_0 FAD linked oxidase K00104 - 1.1.3.15 1.735e-239 752.0
WLSH2_k127_3625268_1 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
WLSH2_k127_3625268_2 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 324.0
WLSH2_k127_3625268_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009477 248.0
WLSH2_k127_3625268_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000002662 182.0
WLSH2_k127_3625268_5 Transposase - - - 0.00000000000000000000000000000000000000571 154.0
WLSH2_k127_3625268_6 transposition K07497 - - 0.0000000001675 64.0
WLSH2_k127_3730225_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.053e-223 702.0
WLSH2_k127_3730225_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 523.0
WLSH2_k127_3730225_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 444.0
WLSH2_k127_3730225_3 addiction module killer protein - - - 0.00000000000000000000000007248 106.0
WLSH2_k127_3742511_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.0 1001.0
WLSH2_k127_3742511_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.458e-284 884.0
WLSH2_k127_3742511_10 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
WLSH2_k127_3742511_11 Sulphur globule protein - - - 0.00000000000000000000000000000000000000000000009698 171.0
WLSH2_k127_3742511_12 - - - - 0.00000000000000000000000000000000005417 138.0
WLSH2_k127_3742511_13 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000000000001755 136.0
WLSH2_k127_3742511_14 MerR HTH family regulatory protein K18997 - - 0.0000000000000000000000000000003258 127.0
WLSH2_k127_3742511_15 - - - - 0.00000000000000007637 82.0
WLSH2_k127_3742511_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 556.0
WLSH2_k127_3742511_3 Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 463.0
WLSH2_k127_3742511_4 heat shock protein DnaJ K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 432.0
WLSH2_k127_3742511_5 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 437.0
WLSH2_k127_3742511_6 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 323.0
WLSH2_k127_3742511_7 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 299.0
WLSH2_k127_3742511_8 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000004313 263.0
WLSH2_k127_3742511_9 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000001522 258.0
WLSH2_k127_3757686_0 Belongs to the RimK family K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 533.0
WLSH2_k127_3757686_1 COG0524 Sugar kinases, ribokinase family K00847,K00852,K00892 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.15,2.7.1.4,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 460.0
WLSH2_k127_3757686_10 - - - - 0.0000000000000000000000000000000000000000000000003643 179.0
WLSH2_k127_3757686_11 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000000001812 158.0
WLSH2_k127_3757686_12 Protein of unknown function (DUF1640) - - - 0.0000000000000000000000003997 105.0
WLSH2_k127_3757686_13 dehydrogenase K00001,K12957 - 1.1.1.1 0.0000000000001833 76.0
WLSH2_k127_3757686_14 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000005509 50.0
WLSH2_k127_3757686_2 PFAM Succinylglutamate desuccinylase Aspartoacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 420.0
WLSH2_k127_3757686_3 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 390.0
WLSH2_k127_3757686_4 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 342.0
WLSH2_k127_3757686_5 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 333.0
WLSH2_k127_3757686_6 PFAM Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 321.0
WLSH2_k127_3757686_7 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002072 253.0
WLSH2_k127_3757686_8 Protein of unknown function (DUF1640) - - - 0.00000000000000000000000000000000000000000000000000000000000000855 218.0
WLSH2_k127_3757686_9 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000000000000000000000000000003026 185.0
WLSH2_k127_3786247_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 496.0
WLSH2_k127_3786247_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 329.0
WLSH2_k127_3786247_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 291.0
WLSH2_k127_3786247_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000003246 119.0
WLSH2_k127_3786247_4 - - - - 0.000000000000000000005414 96.0
WLSH2_k127_3801976_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.499e-309 959.0
WLSH2_k127_3801976_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.006e-264 835.0
WLSH2_k127_3801976_10 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000002885 209.0
WLSH2_k127_3801976_11 mercury ion transmembrane transporter activity K01533,K07213 - 3.6.3.4 0.00000000000000305 77.0
WLSH2_k127_3801976_2 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 3.914e-209 668.0
WLSH2_k127_3801976_3 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 585.0
WLSH2_k127_3801976_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 565.0
WLSH2_k127_3801976_5 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 484.0
WLSH2_k127_3801976_6 Transcriptional regulator, LysR K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 457.0
WLSH2_k127_3801976_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 342.0
WLSH2_k127_3801976_8 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
WLSH2_k127_3801976_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006159 231.0
WLSH2_k127_3821955_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 356.0
WLSH2_k127_386013_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 538.0
WLSH2_k127_386013_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 367.0
WLSH2_k127_386013_2 Iron--sulfur cluster insertion protein erpA K15724 - - 0.00000000000000000000000000000000000000000000000000000000004855 207.0
WLSH2_k127_386013_3 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000000000000000000000000000000002693 191.0
WLSH2_k127_386013_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000009786 200.0
WLSH2_k127_386013_5 Domain of unknown function (DUF5063) - - - 0.00000000000000000000000000000000000000000000003555 176.0
WLSH2_k127_386013_6 - - - - 0.000000000000000000000000004033 121.0
WLSH2_k127_386013_7 Polymer-forming cytoskeletal - - - 0.00000000000000000000001164 109.0
WLSH2_k127_386013_8 - - - - 0.0002582 46.0
WLSH2_k127_3867586_0 - - - - 9.234e-217 698.0
WLSH2_k127_3867917_0 Peptidase family M1 domain - - - 2.757e-249 788.0
WLSH2_k127_3867917_1 Nitroreductase family - - - 1.079e-198 632.0
WLSH2_k127_3867917_2 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000008342 192.0
WLSH2_k127_3867917_3 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000000000000001977 180.0
WLSH2_k127_3867917_4 - - - - 0.000000000000000000000000000000000000000002116 162.0
WLSH2_k127_387873_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1530.0
WLSH2_k127_387873_1 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 3.563e-304 944.0
WLSH2_k127_387873_10 - - - - 0.000000000000000000000000000000000008133 149.0
WLSH2_k127_387873_11 Domain of unknown function (DUF4381) - - - 0.0000000000000003255 84.0
WLSH2_k127_387873_12 Universal stress protein family - - - 0.000000000003127 77.0
WLSH2_k127_387873_2 His Kinase A (phosphoacceptor) domain - - - 4.898e-230 737.0
WLSH2_k127_387873_3 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 514.0
WLSH2_k127_387873_4 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 432.0
WLSH2_k127_387873_5 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 376.0
WLSH2_k127_387873_6 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 374.0
WLSH2_k127_387873_7 Psort location CytoplasmicMembrane, score 10.00 K08974 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008641 355.0
WLSH2_k127_387873_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 344.0
WLSH2_k127_387873_9 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000009217 166.0
WLSH2_k127_3915104_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 522.0
WLSH2_k127_3915104_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
WLSH2_k127_3917043_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1037.0
WLSH2_k127_3917043_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000001882 229.0
WLSH2_k127_3917043_2 - - - - 0.0000000000000000000000000000000000000000000001036 173.0
WLSH2_k127_3917043_3 - - - - 0.0000000002189 62.0
WLSH2_k127_3941710_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1572.0
WLSH2_k127_3941710_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1177.0
WLSH2_k127_3941710_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 404.0
WLSH2_k127_3961554_0 Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 549.0
WLSH2_k127_3961554_1 - - - - 0.00000000000000001251 85.0
WLSH2_k127_3961554_2 IstB-like ATP binding protein - - - 0.000000000000008873 79.0
WLSH2_k127_3978470_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1047.0
WLSH2_k127_3978470_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.684e-272 852.0
WLSH2_k127_3978470_10 - - - - 0.00000000000000000000000000000000002449 137.0
WLSH2_k127_3978470_11 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.00000000000000000000000000000006371 128.0
WLSH2_k127_3978470_12 - - - - 0.0000000000000000000000006131 107.0
WLSH2_k127_3978470_13 Belongs to the 'phage' integrase family - - - 0.000000000000000000000688 94.0
WLSH2_k127_3978470_14 - - - - 0.000000000000000000002763 97.0
WLSH2_k127_3978470_16 COG1943 Transposase and inactivated derivatives K07491 - - 0.000003838 54.0
WLSH2_k127_3978470_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.162e-251 790.0
WLSH2_k127_3978470_3 (C AC39) subunit K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 397.0
WLSH2_k127_3978470_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 355.0
WLSH2_k127_3978470_5 V-type proton ATPase subunit E K02121 - - 0.0000000000000000000000000000000000000000000000000000000000000000003769 235.0
WLSH2_k127_3978470_6 ATP synthase subunit C K02124 - - 0.000000000000000000000000000000000000000000000000000000000000007107 224.0
WLSH2_k127_3978470_7 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000000000001189 206.0
WLSH2_k127_3978470_8 Helix-turn-helix K21498 - - 0.00000000000000000000000000000000000000000000001273 172.0
WLSH2_k127_3978470_9 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000001009 146.0
WLSH2_k127_3997058_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.128e-222 697.0
WLSH2_k127_3997058_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 490.0
WLSH2_k127_3997058_2 NUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.00000000000000000000000000000000000000005987 159.0
WLSH2_k127_4005853_0 belongs to the CobB CobQ family K13788 - 2.3.1.8 1.002e-318 988.0
WLSH2_k127_4005853_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.4e-253 782.0
WLSH2_k127_4005853_10 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000105 199.0
WLSH2_k127_4005853_12 - - - - 0.0000000000000000000000004976 106.0
WLSH2_k127_4005853_13 sulfurtransferase - - - 0.00005401 46.0
WLSH2_k127_4005853_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 5.537e-197 628.0
WLSH2_k127_4005853_3 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 564.0
WLSH2_k127_4005853_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 531.0
WLSH2_k127_4005853_5 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 447.0
WLSH2_k127_4005853_6 subfamily IA, variant 3 K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 338.0
WLSH2_k127_4005853_7 RNA ligase K07468 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001489 269.0
WLSH2_k127_4005853_8 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005323 255.0
WLSH2_k127_4005853_9 PFAM NUDIX hydrolase K08312 - - 0.0000000000000000000000000000000000000000000000000000000000000001636 225.0
WLSH2_k127_4007095_0 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K07006,K21832 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 563.0
WLSH2_k127_4007095_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 338.0
WLSH2_k127_4007095_2 Class III cytochrome C family - - - 0.000000000000000000000000000000000006351 139.0
WLSH2_k127_4007095_3 Transposase - - - 0.00000000000002208 81.0
WLSH2_k127_4007095_4 abc transporter atp-binding protein K06158 - - 0.000003062 52.0
WLSH2_k127_4008669_0 PFAM Lytic K08309 - - 1.067e-222 713.0
WLSH2_k127_4008669_1 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 348.0
WLSH2_k127_4008669_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 308.0
WLSH2_k127_4008669_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 284.0
WLSH2_k127_4008669_4 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004466 234.0
WLSH2_k127_4008669_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000002439 171.0
WLSH2_k127_4041310_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1274.0
WLSH2_k127_4041310_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 290.0
WLSH2_k127_4045942_0 Protein of unknown function (DUF3050) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 376.0
WLSH2_k127_4045942_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007326 259.0
WLSH2_k127_4045942_2 PFAM HPP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
WLSH2_k127_4045942_3 Part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000000000004732 170.0
WLSH2_k127_4045942_4 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000368 160.0
WLSH2_k127_4105542_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006824 272.0
WLSH2_k127_4105542_1 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000001212 229.0
WLSH2_k127_4105542_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000003755 173.0
WLSH2_k127_4105542_3 O-Antigen ligase - - - 0.00000000000000000000000000000000000006157 160.0
WLSH2_k127_4105542_4 polysaccharide export K01991 - - 0.00000000000000000000000000000001666 138.0
WLSH2_k127_4105542_5 protein involved in exopolysaccharide biosynthesis K16554 - - 0.0000000000000000000008015 112.0
WLSH2_k127_4109321_0 PFAM malic K00029 - 1.1.1.40 2.246e-234 736.0
WLSH2_k127_412032_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0 1026.0
WLSH2_k127_412032_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 3.681e-233 728.0
WLSH2_k127_412032_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 520.0
WLSH2_k127_412032_3 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 392.0
WLSH2_k127_412032_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001307 278.0
WLSH2_k127_412032_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005738 244.0
WLSH2_k127_412032_6 - - - - 0.00000000000000000000000000000000000000000000000000001165 190.0
WLSH2_k127_412032_7 - - - - 0.0000000000000000007464 88.0
WLSH2_k127_4155383_0 4Fe-4S dicluster domain - - - 1.288e-311 968.0
WLSH2_k127_4155383_1 electron transfer flavoprotein, alpha subunit K03522 - - 1.297e-208 655.0
WLSH2_k127_417571_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1313.0
WLSH2_k127_417571_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 1.995e-319 993.0
WLSH2_k127_417571_10 Protein of unknown function (DUF2782) - - - 0.000000000000000000000000002701 114.0
WLSH2_k127_417571_12 Protein of unknown function (DUF433) - - - 0.0003061 43.0
WLSH2_k127_417571_2 Belongs to the thiolase family K00626 - 2.3.1.9 2.645e-224 698.0
WLSH2_k127_417571_3 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.21e-210 664.0
WLSH2_k127_417571_4 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000861 577.0
WLSH2_k127_417571_5 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 539.0
WLSH2_k127_417571_6 PFAM Xanthine uracil vitamin C permease K03458,K16345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 368.0
WLSH2_k127_417571_7 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 231.0
WLSH2_k127_417571_8 Uncharacterized protein conserved in bacteria (DUF2076) K09945 - - 0.00000000000000000000000000000000000000000000000001782 189.0
WLSH2_k127_417571_9 PFAM Cache K08738 - - 0.000000000000000000000000000000000000004384 157.0
WLSH2_k127_4186512_0 mechanosensitive ion channel K05802 - - 5.947e-293 936.0
WLSH2_k127_4186512_1 inner membrane component K02011 - - 3.535e-257 799.0
WLSH2_k127_4186512_2 ErfK YbiS YcfS YnhG family protein K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 529.0
WLSH2_k127_4186512_3 PFAM Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 527.0
WLSH2_k127_4186512_4 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 488.0
WLSH2_k127_4186512_5 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 435.0
WLSH2_k127_4186512_6 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 354.0
WLSH2_k127_4186512_7 Membrane - - - 0.000000000000000000002095 94.0
WLSH2_k127_4192022_0 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001595 281.0
WLSH2_k127_4192022_1 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001234 275.0
WLSH2_k127_4192022_2 4-hydroxybenzoate synthetase (Chorismate lyase) K03181 - 4.1.3.40 0.0000000000000000000000000000000000000000000000000000000000000000000000002357 253.0
WLSH2_k127_4192022_3 PFAM Integrase catalytic - - - 0.00000000000000000000001816 113.0
WLSH2_k127_4218692_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009557 385.0
WLSH2_k127_4218692_1 FimV C-terminal K08086 - - 0.00000000000000001554 95.0
WLSH2_k127_4252509_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 396.0
WLSH2_k127_4252509_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000004853 128.0
WLSH2_k127_4252509_2 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000006603 132.0
WLSH2_k127_426012_0 DNA RNA helicase K03580 - - 0.0 1746.0
WLSH2_k127_426012_1 Protein of unknown function DUF262 - - - 0.0 1206.0
WLSH2_k127_426012_10 Helix-hairpin-helix domain - - - 0.000008735 54.0
WLSH2_k127_426012_2 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 340.0
WLSH2_k127_426012_3 DNA methylAse K15984 - 2.1.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 297.0
WLSH2_k127_426012_4 gag-polyprotein putative aspartyl protease - - - 0.000000000000000000000000000000000000000000000000000000000001575 220.0
WLSH2_k127_426012_5 PFAM Ankyrin K06867 - - 0.0000000000000000000000000000000000000000000000000000000009996 209.0
WLSH2_k127_426012_6 - - - - 0.0000000000000000000000000000000000000000000000000000003935 198.0
WLSH2_k127_426012_7 - - - - 0.000000000000000000000000000000000000006917 156.0
WLSH2_k127_426012_8 - - - - 0.000000000000000000000000001834 116.0
WLSH2_k127_426012_9 DDE_Tnp_1-associated - - - 0.000000000000000000000001268 106.0
WLSH2_k127_4286230_0 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 428.0
WLSH2_k127_4286230_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 381.0
WLSH2_k127_4286230_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 315.0
WLSH2_k127_4286230_3 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000002348 235.0
WLSH2_k127_4286230_4 PFAM Smr - - - 0.0000000000000000000000000000000000000000000000000000000000288 213.0
WLSH2_k127_432554_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1579.0
WLSH2_k127_432554_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1218.0
WLSH2_k127_432554_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 576.0
WLSH2_k127_432554_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002426 246.0
WLSH2_k127_432554_4 Protein of unknown function (DUF1778) - - - 0.000000000000000000000000000000000000000001463 157.0
WLSH2_k127_432554_5 protein conserved in bacteria - - - 0.000000000000000004696 85.0
WLSH2_k127_432554_6 Metallo-beta-lactamase superfamily - - - 0.000000000000001446 78.0
WLSH2_k127_432554_7 Domain of unknown function (DUF4143) K07133 - - 0.0000009651 52.0
WLSH2_k127_432554_8 von Willebrand factor type A domain K07114 - - 0.000008864 48.0
WLSH2_k127_4349137_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 6.517e-217 679.0
WLSH2_k127_4349137_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 562.0
WLSH2_k127_4349137_2 PFAM Cold-shock K03704 - - 0.0000000000000000000000000000000001349 133.0
WLSH2_k127_4379188_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 1.199e-304 953.0
WLSH2_k127_4379188_1 Helicase K03722 - 3.6.4.12 4.779e-281 876.0
WLSH2_k127_4379188_2 Extracellular solute-binding protein, family 5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 563.0
WLSH2_k127_4379188_3 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 461.0
WLSH2_k127_4379188_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 427.0
WLSH2_k127_4379188_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 396.0
WLSH2_k127_4379188_6 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 319.0
WLSH2_k127_4379188_7 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000001966 140.0
WLSH2_k127_4379188_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001185 140.0
WLSH2_k127_4512141_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 465.0
WLSH2_k127_4512141_1 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 426.0
WLSH2_k127_4512141_2 component of anaerobic - - - 0.0000000000000000000000000000000000000000000000000001441 196.0
WLSH2_k127_4512141_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000001114 149.0
WLSH2_k127_4512141_4 - - - - 0.000000000000000000000000005329 112.0
WLSH2_k127_4524071_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.49e-200 634.0
WLSH2_k127_4524071_1 CobB/CobQ-like glutamine amidotransferase domain K02224 - 6.3.5.11,6.3.5.9 1.254e-197 627.0
WLSH2_k127_4524071_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 320.0
WLSH2_k127_4524071_3 Cobalt uptake substrate-specific transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 293.0
WLSH2_k127_4524071_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000005879 62.0
WLSH2_k127_454869_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 339.0
WLSH2_k127_454869_1 - - - - 0.00000000000000000000000000000000000000000000000000000003005 203.0
WLSH2_k127_4575097_0 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 483.0
WLSH2_k127_4575097_1 General secretion pathway protein M K02462 - - 0.000000000000000000000000000000000000000000000000000001749 198.0
WLSH2_k127_4575097_2 Pfam:T4SC K02463 - - 0.000000000000000000000000000002971 127.0
WLSH2_k127_4575097_3 fimbrial assembly K02461 - - 0.000000000000000000000000000115 118.0
WLSH2_k127_460776_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1762.0
WLSH2_k127_4615975_0 Isocitrate lyase K01637 - 4.1.3.1 1.165e-252 782.0
WLSH2_k127_4615975_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 0.0000000000000000000000000000000000000354 145.0
WLSH2_k127_4635741_0 Ion transport 2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 601.0
WLSH2_k127_4635741_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 520.0
WLSH2_k127_4635741_2 Osmosensitive K channel histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 391.0
WLSH2_k127_4635741_3 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 291.0
WLSH2_k127_4635741_4 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001196 271.0
WLSH2_k127_4635741_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000009841 207.0
WLSH2_k127_4635741_6 CBS domain - - - 0.0000000000000000000000000000000000000000000000003643 179.0
WLSH2_k127_4658004_0 PFAM Na Picotransporter K03324 - - 1.753e-235 738.0
WLSH2_k127_4658004_1 Putative transposase, YhgA-like - - - 0.00000000000000000000000000001092 120.0
WLSH2_k127_4658004_2 Putative transposase, YhgA-like - - - 0.00000000000000000000000000003657 118.0
WLSH2_k127_4715041_0 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000001179 244.0
WLSH2_k127_4715041_1 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000000000000000000000000000000000000000000000000000005162 233.0
WLSH2_k127_4715041_2 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000002776 217.0
WLSH2_k127_4715041_3 fimbrial assembly K02461 - - 0.00000000000000000000000000000000000000000000000000000892 200.0
WLSH2_k127_4715041_4 General secretion pathway protein H K02457 - - 0.000000000000000000000000000000000000000000003044 169.0
WLSH2_k127_4715041_5 Pfam:N_methyl_2 K02458 - - 0.00000000000000000000000000003647 123.0
WLSH2_k127_4715041_6 pfam abc K01990,K09691 - - 0.000002467 50.0
WLSH2_k127_4758446_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 531.0
WLSH2_k127_4758446_1 Drug resistance transporter Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 518.0
WLSH2_k127_4758446_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 374.0
WLSH2_k127_4758446_3 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002559 268.0
WLSH2_k127_4758446_4 TIGRFAM 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000001524 87.0
WLSH2_k127_4818217_0 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 535.0
WLSH2_k127_4818217_1 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 335.0
WLSH2_k127_4818217_2 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 283.0
WLSH2_k127_4818217_3 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000008949 177.0
WLSH2_k127_484120_0 Peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 606.0
WLSH2_k127_484120_1 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 490.0
WLSH2_k127_484120_2 nhl repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 445.0
WLSH2_k127_484120_3 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 378.0
WLSH2_k127_484120_4 PFAM L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000111 225.0
WLSH2_k127_484120_5 lipid carrier protein - - - 0.000000000000000000000000000000000000000000000000000000000000856 216.0
WLSH2_k127_4970157_0 Extracellular solute-binding protein, family 5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 603.0
WLSH2_k127_4970157_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000009481 137.0
WLSH2_k127_4976376_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 3.689e-245 768.0
WLSH2_k127_4976376_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 555.0
WLSH2_k127_4976376_2 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 294.0
WLSH2_k127_4976376_3 Sodium hydrogen exchanger K11105 - - 0.000000000000000000000000000000000000000001089 166.0
WLSH2_k127_4983323_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.0 1028.0
WLSH2_k127_4983323_1 Part of a membrane complex involved in electron transport K03615 - - 5.062e-218 686.0
WLSH2_k127_4983323_2 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 558.0
WLSH2_k127_4983323_3 PFAM Oxidoreductase FAD NAD(P)-binding K00380,K02641 - 1.18.1.2,1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 421.0
WLSH2_k127_4983323_4 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 349.0
WLSH2_k127_4983323_5 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 299.0
WLSH2_k127_4983323_6 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001308 272.0
WLSH2_k127_4983323_7 - - - - 0.00000000000000000000000000000000000000000000000000000000001152 209.0
WLSH2_k127_4983323_8 ATPase (AAA superfamily K06922 - - 0.00000000000000000000000000001327 118.0
WLSH2_k127_4983323_9 - - - - 0.000000000000129 73.0
WLSH2_k127_5020372_0 Fic/DOC family - - - 8.401e-204 645.0
WLSH2_k127_5020372_1 Domain of unknown function DUF29 - - - 0.00000000000000001425 84.0
WLSH2_k127_5022707_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.865e-220 692.0
WLSH2_k127_5022707_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 455.0
WLSH2_k127_5022707_2 addiction module antidote protein - - - 0.00000000000000000000000000000000000000000000000000000009498 197.0
WLSH2_k127_5022707_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000008242 199.0
WLSH2_k127_5022707_4 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.000000000000000000000000000000005866 129.0
WLSH2_k127_5022707_5 addiction module killer protein - - - 0.000000000128 61.0
WLSH2_k127_5022707_6 Protein of unknown function DUF262 - - - 0.000000000648 65.0
WLSH2_k127_5026466_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1000.0
WLSH2_k127_5026466_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.229e-195 612.0
WLSH2_k127_5026466_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 569.0
WLSH2_k127_5026466_3 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 286.0
WLSH2_k127_5030390_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 1.601e-264 826.0
WLSH2_k127_5037207_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1169.0
WLSH2_k127_5037207_1 Putative ATP-dependent Lon protease K01338 - 3.4.21.53 0.0 1157.0
WLSH2_k127_5037207_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000005418 118.0
WLSH2_k127_5037207_11 Protein of unknown function DUF86 - - - 0.000000000000000000000000003104 114.0
WLSH2_k127_5037207_12 - - - - 0.000000000000000000001895 100.0
WLSH2_k127_5037207_13 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000003411 72.0
WLSH2_k127_5037207_2 PglZ domain - - - 5.83e-242 773.0
WLSH2_k127_5037207_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 6.545e-218 693.0
WLSH2_k127_5037207_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.424e-207 654.0
WLSH2_k127_5037207_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 544.0
WLSH2_k127_5037207_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 394.0
WLSH2_k127_5037207_7 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 294.0
WLSH2_k127_5037207_8 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000001623 213.0
WLSH2_k127_5037207_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000000000000003399 127.0
WLSH2_k127_5067441_0 Part of a membrane complex involved in electron transport K03615 - - 1.302e-201 636.0
WLSH2_k127_5067441_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 539.0
WLSH2_k127_5067441_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 460.0
WLSH2_k127_5067441_3 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00171,K00172,K02573,K03737,K13795,K18930 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 428.0
WLSH2_k127_5067441_4 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 306.0
WLSH2_k127_5067441_5 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 299.0
WLSH2_k127_5067441_6 High frequency lysogenization protein HflD homolog K07153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 253.0
WLSH2_k127_5067441_7 Part of a membrane complex involved in electron transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006751 252.0
WLSH2_k127_5067441_8 response regulator receiver - - - 0.00000000000000000000000000000000000000000005154 164.0
WLSH2_k127_5067441_9 - - - - 0.0000000000000000000000000000000000001853 143.0
WLSH2_k127_5109786_0 AAA ATPase, central domain protein K07478 - - 4.49e-212 666.0
WLSH2_k127_5109786_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 495.0
WLSH2_k127_5109786_2 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 411.0
WLSH2_k127_5109786_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 323.0
WLSH2_k127_5109786_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001672 267.0
WLSH2_k127_5109786_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000001137 223.0
WLSH2_k127_5109786_6 Hemerythrin HHE cation binding domain - - - 0.00000000002651 68.0
WLSH2_k127_5162813_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1166.0
WLSH2_k127_5162813_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1110.0
WLSH2_k127_5162813_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 372.0
WLSH2_k127_5162813_11 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
WLSH2_k127_5162813_12 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 294.0
WLSH2_k127_5162813_13 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000172 253.0
WLSH2_k127_5162813_14 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000004383 250.0
WLSH2_k127_5162813_15 PFAM Outer membrane K06142 - - 0.00000000000000000000000000000000000000000001209 169.0
WLSH2_k127_5162813_16 - - - - 0.000000000000000000000000000000000001635 140.0
WLSH2_k127_5162813_17 - - - - 0.000000000000000000000000007205 116.0
WLSH2_k127_5162813_18 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000001842 109.0
WLSH2_k127_5162813_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.079e-295 923.0
WLSH2_k127_5162813_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 3.097e-221 696.0
WLSH2_k127_5162813_4 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 553.0
WLSH2_k127_5162813_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 531.0
WLSH2_k127_5162813_6 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 454.0
WLSH2_k127_5162813_7 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 434.0
WLSH2_k127_5162813_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 422.0
WLSH2_k127_5162813_9 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 419.0
WLSH2_k127_5227029_0 CoA-binding domain protein K09181 - - 1.492e-306 963.0
WLSH2_k127_5228094_0 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 1.724e-211 672.0
WLSH2_k127_5228094_1 Type II secretion system K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 564.0
WLSH2_k127_5228094_2 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 507.0
WLSH2_k127_5228094_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 376.0
WLSH2_k127_5228094_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000003289 154.0
WLSH2_k127_5294779_0 Citrate transporter - - - 1.28e-286 893.0
WLSH2_k127_5294779_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 578.0
WLSH2_k127_5294779_2 PFAM 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 457.0
WLSH2_k127_5294779_3 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 434.0
WLSH2_k127_5294779_4 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 339.0
WLSH2_k127_5294779_5 lysine 2,3-aminomutase K19810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 332.0
WLSH2_k127_5294779_6 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 324.0
WLSH2_k127_5294779_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002753 248.0
WLSH2_k127_5294779_8 PFAM EAL domain K21025 - - 0.000000000000000000000000000000000000000000000000000000000000001611 234.0
WLSH2_k127_5294779_9 - - - - 0.000000000000000003679 86.0
WLSH2_k127_5382267_0 TIGRFAM ribonuclease, Rne Rng family K08301 - - 2.256e-267 828.0
WLSH2_k127_5382267_1 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 597.0
WLSH2_k127_5382267_2 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 569.0
WLSH2_k127_5382267_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
WLSH2_k127_5382267_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000001518 235.0
WLSH2_k127_5391028_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 595.0
WLSH2_k127_5391028_1 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
WLSH2_k127_5391028_2 Major royal jelly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 367.0
WLSH2_k127_5391028_3 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000005347 144.0
WLSH2_k127_5391028_4 PFAM Alpha beta hydrolase K07019 - - 0.00000001723 58.0
WLSH2_k127_5530241_0 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 519.0
WLSH2_k127_5530241_1 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 428.0
WLSH2_k127_5530241_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 406.0
WLSH2_k127_5530241_3 Ion transport protein - - - 0.00000000000000000000000000000000000000000000000000000006018 205.0
WLSH2_k127_5530241_4 Fusaric acid resistance protein-like - - - 0.0000000000000000000000000000000000000000000001732 174.0
WLSH2_k127_5530241_5 CorA-like Mg2+ transporter protein K16074 - - 0.0000000000000000000000000000000000001659 156.0
WLSH2_k127_5530241_6 Pfam Transposase - - - 0.00000000000000000000000007325 110.0
WLSH2_k127_5530241_7 Protein of unknown function (DUF4239) - - - 0.000000000008799 69.0
WLSH2_k127_5530241_8 MgtC family K07507 - - 0.00000003861 56.0
WLSH2_k127_5571290_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 7.938e-285 882.0
WLSH2_k127_5571290_1 Nucleotidyltransferase substrate binding protein like - - - 0.0000000000000000000000000000000000000000000000000000005832 196.0
WLSH2_k127_5571290_2 HsdM N-terminal domain K03427 - 2.1.1.72 0.000000000000000000000000000000000004841 140.0
WLSH2_k127_5571290_3 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000002059 135.0
WLSH2_k127_5593766_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 8.28e-275 856.0
WLSH2_k127_5593766_1 PFAM Pentapeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 307.0
WLSH2_k127_5593766_2 PFAM Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001738 277.0
WLSH2_k127_5635684_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1161.0
WLSH2_k127_5635684_1 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000003896 104.0
WLSH2_k127_5635684_2 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.00001032 50.0
WLSH2_k127_5638636_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1446.0
WLSH2_k127_5638636_1 heat shock protein 70 - - - 2.632e-258 806.0
WLSH2_k127_5638636_10 PFAM heat shock protein DnaJ - - - 0.000000000000000000000000000001235 123.0
WLSH2_k127_5638636_2 Thiamine pyrophosphate enzyme, central domain - - - 5.04e-241 758.0
WLSH2_k127_5638636_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 574.0
WLSH2_k127_5638636_4 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 526.0
WLSH2_k127_5638636_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 457.0
WLSH2_k127_5638636_6 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000013 219.0
WLSH2_k127_5638636_7 - - - - 0.000000000000000000000000000000000000000000000000000000000005067 216.0
WLSH2_k127_5638636_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000001625 193.0
WLSH2_k127_5638636_9 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000707 131.0
WLSH2_k127_5641310_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 417.0
WLSH2_k127_5641310_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000002842 113.0
WLSH2_k127_5641310_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000001857 90.0
WLSH2_k127_5653804_0 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 386.0
WLSH2_k127_5653804_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000002412 177.0
WLSH2_k127_5653804_2 Belongs to the 'phage' integrase family - - - 0.00000000000000002285 82.0
WLSH2_k127_5686388_0 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000003738 226.0
WLSH2_k127_5686388_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000006475 166.0
WLSH2_k127_5686388_2 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000386 130.0
WLSH2_k127_5737697_0 PFAM Ammonium Transporter K03320 - - 8.119e-223 694.0
WLSH2_k127_5737697_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 332.0
WLSH2_k127_5737697_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 312.0
WLSH2_k127_5737697_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 291.0
WLSH2_k127_5737697_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 277.0
WLSH2_k127_5737697_5 integral membrane protein K02221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000182 247.0
WLSH2_k127_5737697_6 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000001433 121.0
WLSH2_k127_5780465_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 507.0
WLSH2_k127_5780465_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 467.0
WLSH2_k127_5780465_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000005677 238.0
WLSH2_k127_5816541_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.945e-307 945.0
WLSH2_k127_5816541_1 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 1.491e-203 646.0
WLSH2_k127_5816541_10 Protein of unknown function (DUF2909) - - - 0.00000000000000000002507 94.0
WLSH2_k127_5816541_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 537.0
WLSH2_k127_5816541_3 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 435.0
WLSH2_k127_5816541_4 PFAM conserved K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 397.0
WLSH2_k127_5816541_5 catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 322.0
WLSH2_k127_5816541_6 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004541 264.0
WLSH2_k127_5816541_7 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000000000844 212.0
WLSH2_k127_5816541_8 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000000000000009123 185.0
WLSH2_k127_5816541_9 SURF1-like protein K14998 - - 0.00000000000000000000000004981 113.0
WLSH2_k127_5840662_0 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 613.0
WLSH2_k127_5840662_1 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 321.0
WLSH2_k127_5840662_2 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 329.0
WLSH2_k127_5840662_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000002954 217.0
WLSH2_k127_5840662_4 TIGRFAM peptidyl-prolyl cis-trans isomerase, EpsD family - - - 0.000000000000000000000000000000000000000001193 168.0
WLSH2_k127_5840662_5 Polysaccharide biosynthesis/export protein - - - 0.00000000000000000000000001119 114.0
WLSH2_k127_5840662_6 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.0000000000008154 76.0
WLSH2_k127_5840662_7 PEP-CTERM protein sorting domain - - - 0.00000009861 61.0
WLSH2_k127_5846459_0 Response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000004259 188.0
WLSH2_k127_5846459_1 CheW-like domain - - - 0.000000000000000000000000000000000000002898 152.0
WLSH2_k127_5846459_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000002671 142.0
WLSH2_k127_5846459_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000006976 130.0
WLSH2_k127_5861051_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.183e-227 710.0
WLSH2_k127_5861051_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 479.0
WLSH2_k127_5861051_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 447.0
WLSH2_k127_5861051_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 320.0
WLSH2_k127_5861051_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000008656 263.0
WLSH2_k127_5861051_6 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000002082 133.0
WLSH2_k127_5861051_7 protein conserved in bacteria - - - 0.00000000000000000000000000005473 120.0
WLSH2_k127_5861051_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000001877 122.0
WLSH2_k127_5861051_9 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000001821 102.0
WLSH2_k127_5900994_0 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 549.0
WLSH2_k127_5900994_1 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 517.0
WLSH2_k127_5900994_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 432.0
WLSH2_k127_5900994_3 Phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 306.0
WLSH2_k127_5900994_4 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000002472 140.0
WLSH2_k127_5901509_0 CoA binding domain K09181 - - 8.401e-279 885.0
WLSH2_k127_5901509_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004348 284.0
WLSH2_k127_5901509_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000005589 117.0
WLSH2_k127_5901509_3 Oxidoreductase FAD-binding domain - - - 0.000000000000001004 79.0
WLSH2_k127_5901509_4 Phosphopantetheine attachment site - - - 0.0000000000001919 74.0
WLSH2_k127_5936105_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.497e-224 703.0
WLSH2_k127_5936105_1 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 6.407e-211 662.0
WLSH2_k127_5936105_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 297.0
WLSH2_k127_5936105_11 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 290.0
WLSH2_k127_5936105_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009932 251.0
WLSH2_k127_5936105_13 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000007716 231.0
WLSH2_k127_5936105_14 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000000000002449 220.0
WLSH2_k127_5936105_15 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000001507 147.0
WLSH2_k127_5936105_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 2.976e-210 663.0
WLSH2_k127_5936105_3 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 602.0
WLSH2_k127_5936105_4 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 547.0
WLSH2_k127_5936105_5 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000998 539.0
WLSH2_k127_5936105_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 523.0
WLSH2_k127_5936105_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 497.0
WLSH2_k127_5936105_8 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 355.0
WLSH2_k127_5936105_9 Oxidoreductase FAD-binding domain K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 310.0
WLSH2_k127_5948723_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 547.0
WLSH2_k127_5948723_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 348.0
WLSH2_k127_5948723_2 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000003686 205.0
WLSH2_k127_5948723_3 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000002118 180.0
WLSH2_k127_5948723_4 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000000002731 168.0
WLSH2_k127_5948723_5 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000169 154.0
WLSH2_k127_5948723_6 PIN domain - - - 0.00000000000000000000000000000000000001568 145.0
WLSH2_k127_5948723_7 Tol-Pal system TolA K03646 - - 0.000000000000000000000000000000000005458 154.0
WLSH2_k127_5948723_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000005291 85.0
WLSH2_k127_599830_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 7.166e-295 915.0
WLSH2_k127_599830_1 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 322.0
WLSH2_k127_599830_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000002092 109.0
WLSH2_k127_6071655_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1456.0
WLSH2_k127_6071655_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 576.0
WLSH2_k127_6071655_10 lipid catabolic process - - - 0.0000000000000000000000001379 119.0
WLSH2_k127_6071655_11 Nitrate TMAO reductase, membrane-bound tetraheme cytochrome c subunit - - - 0.0000000000000001699 81.0
WLSH2_k127_6071655_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 517.0
WLSH2_k127_6071655_3 PFAM Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 495.0
WLSH2_k127_6071655_4 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 299.0
WLSH2_k127_6071655_5 PFAM HhH-GPD K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 308.0
WLSH2_k127_6071655_6 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001468 264.0
WLSH2_k127_6071655_7 - - - - 0.0000000000000000000000000000000000000000000000008097 183.0
WLSH2_k127_6071655_8 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000000001854 168.0
WLSH2_k127_6071655_9 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000305 149.0
WLSH2_k127_6090983_0 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008718 584.0
WLSH2_k127_6090983_1 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000003237 179.0
WLSH2_k127_6090983_2 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000128 96.0
WLSH2_k127_609752_0 efflux pump K18138 - - 0.0 1259.0
WLSH2_k127_609752_1 regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001313 244.0
WLSH2_k127_609752_2 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000003001 174.0
WLSH2_k127_609752_3 enzyme of the cupin superfamily K06995 - - 0.0000000000000000000000000000000000000000000001318 170.0
WLSH2_k127_6107259_0 Seven times multi-haem cytochrome CxxCH - - - 1.171e-287 889.0
WLSH2_k127_6107259_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.665e-261 809.0
WLSH2_k127_6107259_10 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
WLSH2_k127_6107259_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 352.0
WLSH2_k127_6107259_12 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 301.0
WLSH2_k127_6107259_13 Fe-S oxidoreductase K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 298.0
WLSH2_k127_6107259_14 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 287.0
WLSH2_k127_6107259_15 ribonuclease BN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006573 286.0
WLSH2_k127_6107259_16 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005864 260.0
WLSH2_k127_6107259_17 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000248 247.0
WLSH2_k127_6107259_18 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001727 227.0
WLSH2_k127_6107259_19 pfam ammecr1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000001399 223.0
WLSH2_k127_6107259_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.816e-223 701.0
WLSH2_k127_6107259_20 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000002857 205.0
WLSH2_k127_6107259_21 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000002811 201.0
WLSH2_k127_6107259_22 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000001757 201.0
WLSH2_k127_6107259_23 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000003107 197.0
WLSH2_k127_6107259_24 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000389 197.0
WLSH2_k127_6107259_25 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000002381 183.0
WLSH2_k127_6107259_26 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000003014 170.0
WLSH2_k127_6107259_27 Part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000001087 155.0
WLSH2_k127_6107259_28 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000001797 146.0
WLSH2_k127_6107259_29 Tetratricopeptide repeats - - - 0.0000000000000000000000000004164 119.0
WLSH2_k127_6107259_3 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 597.0
WLSH2_k127_6107259_30 Ribosomal protein L30 K02907 - - 0.0000000000000000000000006495 104.0
WLSH2_k127_6107259_31 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001141 75.0
WLSH2_k127_6107259_4 LUD domain K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 574.0
WLSH2_k127_6107259_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 541.0
WLSH2_k127_6107259_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 531.0
WLSH2_k127_6107259_7 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 480.0
WLSH2_k127_6107259_8 PFAM Binding-protein-dependent transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 468.0
WLSH2_k127_6107259_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002467 397.0
WLSH2_k127_6128619_0 PFAM binding-protein-dependent transport systems inner membrane component K11070,K11074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 402.0
WLSH2_k127_6128619_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 346.0
WLSH2_k127_6128619_2 PFAM binding-protein-dependent transport systems inner membrane component K11071,K11075 - - 0.00000000000000000000000000000000000000000000000000000000000006828 214.0
WLSH2_k127_6128619_3 - - - - 0.00000000000000000000000000000000000000009597 159.0
WLSH2_k127_6128619_4 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000001521 89.0
WLSH2_k127_6128619_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000005624 61.0
WLSH2_k127_6223787_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1224.0
WLSH2_k127_6223787_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 471.0
WLSH2_k127_6223787_10 - - - - 0.00000000000000000000000000000000000000000003484 168.0
WLSH2_k127_6223787_11 - - - - 0.000000000000000000000000000000006937 130.0
WLSH2_k127_6223787_2 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 460.0
WLSH2_k127_6223787_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 367.0
WLSH2_k127_6223787_4 carbohydrate transport K11688,K21395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004094 349.0
WLSH2_k127_6223787_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 286.0
WLSH2_k127_6223787_6 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 276.0
WLSH2_k127_6223787_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002657 265.0
WLSH2_k127_6223787_8 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000004679 235.0
WLSH2_k127_6223787_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000009673 184.0
WLSH2_k127_6226802_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 489.0
WLSH2_k127_6226802_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.00000000000000000000000000000000000011 142.0
WLSH2_k127_6226802_2 Fibrillarin - - - 0.0000000157 58.0
WLSH2_k127_6232646_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 503.0
WLSH2_k127_6232646_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 474.0
WLSH2_k127_6232646_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000008789 201.0
WLSH2_k127_6232646_3 PFAM Sporulation K03749 - - 0.00000000002635 72.0
WLSH2_k127_6252873_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1103.0
WLSH2_k127_6252873_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1067.0
WLSH2_k127_6252873_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
WLSH2_k127_6252873_11 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000000000000000001608 210.0
WLSH2_k127_6252873_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000004364 206.0
WLSH2_k127_6252873_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000001104 163.0
WLSH2_k127_6252873_14 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000006518 98.0
WLSH2_k127_6252873_15 - - - - 0.000000000000000002679 87.0
WLSH2_k127_6252873_2 DNA segregation ATPase FtsK SpoIIIE K03466 - - 3.163e-254 809.0
WLSH2_k127_6252873_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.554e-222 694.0
WLSH2_k127_6252873_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 592.0
WLSH2_k127_6252873_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 551.0
WLSH2_k127_6252873_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 337.0
WLSH2_k127_6252873_7 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 324.0
WLSH2_k127_6252873_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 294.0
WLSH2_k127_6252873_9 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002357 282.0
WLSH2_k127_6255421_0 Phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 511.0
WLSH2_k127_6255421_1 Protein phosphatase 2A homologues, catalytic domain. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 391.0
WLSH2_k127_6255421_2 COG1283 Na phosphate symporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009224 258.0
WLSH2_k127_6255421_3 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000000000000000000005224 221.0
WLSH2_k127_6271852_0 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 452.0
WLSH2_k127_6271852_1 sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000732 278.0
WLSH2_k127_6271852_2 Membrane - - - 0.00000000000000000000000000000000000000000002597 165.0
WLSH2_k127_6271852_3 Protein of unknown function (DUF1109) - - - 0.00008729 50.0
WLSH2_k127_6300257_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.387e-298 928.0
WLSH2_k127_6300257_1 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 4.97e-209 661.0
WLSH2_k127_6300257_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 293.0
WLSH2_k127_6300257_11 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 290.0
WLSH2_k127_6300257_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006563 254.0
WLSH2_k127_6300257_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000004108 210.0
WLSH2_k127_6300257_14 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000004846 203.0
WLSH2_k127_6300257_16 - K06006 - - 0.000000297 59.0
WLSH2_k127_6300257_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.476e-199 629.0
WLSH2_k127_6300257_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 558.0
WLSH2_k127_6300257_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 542.0
WLSH2_k127_6300257_5 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 534.0
WLSH2_k127_6300257_6 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 427.0
WLSH2_k127_6300257_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 376.0
WLSH2_k127_6300257_8 PFAM UBA THIF-type NAD FAD binding K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 338.0
WLSH2_k127_6300257_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 302.0
WLSH2_k127_6301981_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 2.28e-224 705.0
WLSH2_k127_6301981_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 3.302e-196 614.0
WLSH2_k127_6301981_10 PFAM Rhodanese-like - - - 0.0000000000000000000000000000000000000000000423 162.0
WLSH2_k127_6301981_11 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000000000001961 151.0
WLSH2_k127_6301981_12 - - - - 0.00000000000000000000000000000000000006735 143.0
WLSH2_k127_6301981_13 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000004846 127.0
WLSH2_k127_6301981_14 - - - - 0.000000000000000000000000001307 119.0
WLSH2_k127_6301981_15 manually curated - - - 0.0006046 44.0
WLSH2_k127_6301981_2 AI-2E family transporter K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 513.0
WLSH2_k127_6301981_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 498.0
WLSH2_k127_6301981_4 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 453.0
WLSH2_k127_6301981_5 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 430.0
WLSH2_k127_6301981_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 423.0
WLSH2_k127_6301981_7 excinuclease ABC activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 307.0
WLSH2_k127_6301981_8 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 301.0
WLSH2_k127_6301981_9 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000000000000000000006666 173.0
WLSH2_k127_6326101_0 Histidine kinase - - - 0.0 1239.0
WLSH2_k127_6326101_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 1.616e-287 894.0
WLSH2_k127_6326101_2 Putative nucleotidyltransferase substrate binding domain K07182 - - 4.351e-229 724.0
WLSH2_k127_6326101_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.021e-218 682.0
WLSH2_k127_6326101_4 SAM-dependent methyltransferase K06969 - 2.1.1.191 5.136e-196 617.0
WLSH2_k127_6326101_5 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004129 269.0
WLSH2_k127_6326101_6 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000005461 186.0
WLSH2_k127_6326101_7 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000007308 77.0
WLSH2_k127_6326101_8 - - - - 0.00000006417 56.0
WLSH2_k127_6326101_9 Thioesterase K18700 - 3.1.2.29 0.00006371 46.0
WLSH2_k127_6346630_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.0 1021.0
WLSH2_k127_6346630_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 2.913e-319 989.0
WLSH2_k127_6346630_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 288.0
WLSH2_k127_6346630_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007851 274.0
WLSH2_k127_6346630_12 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004747 269.0
WLSH2_k127_6346630_13 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002478 253.0
WLSH2_k127_6346630_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000002966 173.0
WLSH2_k127_6346630_15 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000001057 134.0
WLSH2_k127_6346630_16 PRTRC system protein D - - - 0.00000000000000000000000008827 111.0
WLSH2_k127_6346630_17 PFAM Rubrerythrin - - - 0.00000000000000000003108 90.0
WLSH2_k127_6346630_2 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 7.374e-268 831.0
WLSH2_k127_6346630_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.324e-254 786.0
WLSH2_k127_6346630_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.141e-247 766.0
WLSH2_k127_6346630_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 8.076e-218 684.0
WLSH2_k127_6346630_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 1.675e-194 609.0
WLSH2_k127_6346630_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 366.0
WLSH2_k127_6346630_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 328.0
WLSH2_k127_6346630_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 323.0
WLSH2_k127_6371058_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1529.0
WLSH2_k127_6371058_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.145e-245 764.0
WLSH2_k127_6371058_10 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
WLSH2_k127_6371058_11 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
WLSH2_k127_6371058_12 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000000000000000005169 178.0
WLSH2_k127_6371058_13 Transposase zinc-binding domain - - - 0.00000000000000000000000000000000000000000004111 164.0
WLSH2_k127_6371058_14 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000002886 144.0
WLSH2_k127_6371058_15 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000001497 133.0
WLSH2_k127_6371058_16 PFAM Integrase, catalytic core - - - 0.00000000000000000000000000000004419 127.0
WLSH2_k127_6371058_17 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000001395 113.0
WLSH2_k127_6371058_18 mRNA binding - - - 0.00000000000000000000000006428 108.0
WLSH2_k127_6371058_19 plasmid stabilization K19092 - - 0.000000000000000000000002368 107.0
WLSH2_k127_6371058_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 8.885e-241 758.0
WLSH2_k127_6371058_20 RNA-directed DNA polymerase (reverse transcriptase) - - - 0.000000000000000000004349 95.0
WLSH2_k127_6371058_21 Cytochrome c - - - 0.000000000000003105 81.0
WLSH2_k127_6371058_22 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.0000007935 58.0
WLSH2_k127_6371058_23 Integrase core domain - - - 0.0006591 45.0
WLSH2_k127_6371058_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.508e-232 720.0
WLSH2_k127_6371058_4 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 595.0
WLSH2_k127_6371058_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 519.0
WLSH2_k127_6371058_6 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 481.0
WLSH2_k127_6371058_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 484.0
WLSH2_k127_6371058_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 401.0
WLSH2_k127_6371058_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 403.0
WLSH2_k127_638159_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 501.0
WLSH2_k127_638159_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000004103 162.0
WLSH2_k127_638159_2 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000001073 101.0
WLSH2_k127_6404359_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.283e-242 760.0
WLSH2_k127_6404359_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 4.59e-223 696.0
WLSH2_k127_6404359_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0000287,GO:0003674,GO:0003824,GO:0004799,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046073,GO:0046385,GO:0046483,GO:0046872,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 474.0
WLSH2_k127_6404359_3 PFAM peptidase K04774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 420.0
WLSH2_k127_6404359_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 398.0
WLSH2_k127_6404359_5 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 367.0
WLSH2_k127_6404359_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
WLSH2_k127_6404359_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000009869 113.0
WLSH2_k127_6404359_8 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000001618 90.0
WLSH2_k127_6516192_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 578.0
WLSH2_k127_6516192_1 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 356.0
WLSH2_k127_6516192_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 329.0
WLSH2_k127_6516192_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 282.0
WLSH2_k127_6516192_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000008844 238.0
WLSH2_k127_6516192_5 PFAM Sulfatase - - - 0.0003772 49.0
WLSH2_k127_6629186_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1430.0
WLSH2_k127_6629186_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.124e-236 739.0
WLSH2_k127_6629186_10 PFAM PilT protein domain protein - - - 0.0000000000000000000000000000000000004254 143.0
WLSH2_k127_6629186_11 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000004959 111.0
WLSH2_k127_6629186_12 Transposase - - - 0.00000000000000000001266 102.0
WLSH2_k127_6629186_13 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.00000000000000178 78.0
WLSH2_k127_6629186_14 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000005916 85.0
WLSH2_k127_6629186_15 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000008559 69.0
WLSH2_k127_6629186_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 587.0
WLSH2_k127_6629186_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 561.0
WLSH2_k127_6629186_4 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 539.0
WLSH2_k127_6629186_5 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 365.0
WLSH2_k127_6629186_6 DNA polymerase III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 305.0
WLSH2_k127_6629186_7 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
WLSH2_k127_6629186_8 Putative ATP-dependent Lon protease K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000008868 194.0
WLSH2_k127_6629186_9 Hemerythrin HHE - - - 0.0000000000000000000000000000000000000000000003137 171.0
WLSH2_k127_6655678_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1354.0
WLSH2_k127_6655678_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1001.0
WLSH2_k127_6655678_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 321.0
WLSH2_k127_6655678_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 312.0
WLSH2_k127_6655678_12 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
WLSH2_k127_6655678_13 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 281.0
WLSH2_k127_6655678_14 DoxX family K15977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008405 246.0
WLSH2_k127_6655678_15 PFAM MucB RseB K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000006708 244.0
WLSH2_k127_6655678_16 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000001164 231.0
WLSH2_k127_6655678_17 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.000000000000000000000000000000000000000000000000002666 184.0
WLSH2_k127_6655678_18 protein conserved in bacteria (DUF2058) K09912 - - 0.00000000000000000000000000000000000000000000000001168 188.0
WLSH2_k127_6655678_19 SnoaL-like domain - - - 0.000000000000000000000000000000001739 134.0
WLSH2_k127_6655678_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 6.684e-277 859.0
WLSH2_k127_6655678_21 PFAM Outer membrane K06142 - - 0.00000000000000000000000000009844 122.0
WLSH2_k127_6655678_22 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000000000000000000000000009457 119.0
WLSH2_k127_6655678_24 Belongs to the UPF0276 family K09930 - - 0.00001591 47.0
WLSH2_k127_6655678_25 PFAM Anti sigma-E protein RseA K03597 - - 0.00001973 54.0
WLSH2_k127_6655678_3 Domain of Unknown Function (DUF349) - - - 9.113e-225 730.0
WLSH2_k127_6655678_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 621.0
WLSH2_k127_6655678_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 439.0
WLSH2_k127_6655678_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 432.0
WLSH2_k127_6655678_7 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 394.0
WLSH2_k127_6655678_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 359.0
WLSH2_k127_6655678_9 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 350.0
WLSH2_k127_6659500_0 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 475.0
WLSH2_k127_6659500_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003529 334.0
WLSH2_k127_6659500_10 DNA polymerase K03502 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003887,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009355,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0019985,GO:0031224,GO:0031668,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044425,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990234 - 0.000000000000002702 79.0
WLSH2_k127_6659500_11 - - - - 0.00000234 50.0
WLSH2_k127_6659500_12 Resolvase - - - 0.000002465 49.0
WLSH2_k127_6659500_2 involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 321.0
WLSH2_k127_6659500_3 DNA methylase K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 288.0
WLSH2_k127_6659500_4 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.00000000000000000000000000000000000000000000000000004222 191.0
WLSH2_k127_6659500_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000001323 156.0
WLSH2_k127_6659500_7 - - - - 0.00000000000000000000000001495 112.0
WLSH2_k127_6659500_8 DNA helicase - - - 0.00000000000000000000001286 100.0
WLSH2_k127_6659500_9 - - - - 0.0000000000000001256 80.0
WLSH2_k127_6672968_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.39e-229 713.0
WLSH2_k127_6672968_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 359.0
WLSH2_k127_6672968_2 PFAM Cytochrome C1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 349.0
WLSH2_k127_6672968_3 PFAM Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 342.0
WLSH2_k127_6672968_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 329.0
WLSH2_k127_6672968_5 NGG1p interacting factor 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 329.0
WLSH2_k127_6672968_6 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000002442 160.0
WLSH2_k127_6672968_7 Protein of unknown function (DUF3301) - - - 0.0000000000000000000000000000000000000000298 155.0
WLSH2_k127_6672968_8 Esterase, phb depolymerase family K03932 - - 0.0000000114 57.0
WLSH2_k127_6688629_0 Methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1453.0
WLSH2_k127_6740970_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00322 - 1.6.1.1 5.016e-261 809.0
WLSH2_k127_6740970_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 609.0
WLSH2_k127_6740970_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 563.0
WLSH2_k127_6740970_3 RNA-binding protein - - - 0.00000000000000000000000000000000000000000006373 161.0
WLSH2_k127_6740970_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000006752 95.0
WLSH2_k127_6740970_5 - - - - 0.0000000000000002878 83.0
WLSH2_k127_6790871_0 synthetase K01908 - 6.2.1.17 0.0 1067.0
WLSH2_k127_6790871_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 5.824e-195 613.0
WLSH2_k127_6790871_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 564.0
WLSH2_k127_6790871_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 476.0
WLSH2_k127_6790871_4 GntR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 293.0
WLSH2_k127_6790871_5 Major facilitator superfamily K08224 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008549 259.0
WLSH2_k127_6790871_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000001408 171.0
WLSH2_k127_6803105_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 1.28e-235 739.0
WLSH2_k127_6831264_0 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 563.0
WLSH2_k127_6831264_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 524.0
WLSH2_k127_6831264_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 422.0
WLSH2_k127_6834291_0 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 452.0
WLSH2_k127_6834291_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 344.0
WLSH2_k127_6834291_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003066 255.0
WLSH2_k127_6834291_3 abc transporter atp-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000001122 194.0
WLSH2_k127_6834291_4 NosL - - - 0.0000000000000000000000000000000000000000000000000002507 192.0
WLSH2_k127_6872717_0 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 371.0
WLSH2_k127_6872717_1 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000001388 234.0
WLSH2_k127_6872717_2 ATPase (AAA superfamily) K06923 - - 0.00000000000000000000000000000000000000000000000003513 180.0
WLSH2_k127_6872717_3 - - - - 0.00000000000000000000000000000000000000000000000006832 189.0
WLSH2_k127_6917001_0 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 298.0
WLSH2_k127_6917001_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009291 257.0
WLSH2_k127_6917001_2 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000007177 173.0
WLSH2_k127_6917001_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000005367 48.0
WLSH2_k127_6920180_0 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 428.0
WLSH2_k127_6920180_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001473 245.0
WLSH2_k127_6952933_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0 1006.0
WLSH2_k127_6952933_1 PFAM Cysteine-rich - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 521.0
WLSH2_k127_69604_0 TIGRFAM Arsenical-resistance protein K03325 - - 8.638e-200 626.0
WLSH2_k127_69604_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 417.0
WLSH2_k127_69604_2 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.00000000000000000000000000000000000000000000000000006717 192.0
WLSH2_k127_69604_3 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000005641 71.0
WLSH2_k127_6991438_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 1.551e-291 905.0
WLSH2_k127_6991438_1 PFAM Mammalian cell entry related K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 578.0
WLSH2_k127_6991438_2 PFAM Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 536.0
WLSH2_k127_6991438_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 359.0
WLSH2_k127_6991438_4 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000000000000000000000000000000000000009537 199.0
WLSH2_k127_7007745_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 2.739e-276 877.0
WLSH2_k127_7007745_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 2.712e-209 660.0
WLSH2_k127_7007745_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 3.784e-203 648.0
WLSH2_k127_7007745_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 6.895e-195 615.0
WLSH2_k127_7007745_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000001834 173.0
WLSH2_k127_7007745_5 phosphoserine phosphatase K01079 GO:0000287,GO:0001505,GO:0003674,GO:0003824,GO:0004647,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006563,GO:0006564,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019752,GO:0042133,GO:0042136,GO:0042578,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046872,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.3 0.000000000000001645 89.0
WLSH2_k127_7101028_0 lipoprotein involved in nitrous oxide reduction - - - 0.000000000000000000000000000000000000000000000000000000006499 205.0
WLSH2_k127_7101028_1 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000001012 179.0
WLSH2_k127_7101028_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000001141 150.0
WLSH2_k127_7112761_0 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 472.0
WLSH2_k127_7112761_1 inner membrane component K02011 - - 0.00000000000000000000000000009967 119.0
WLSH2_k127_7112761_2 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000077 98.0
WLSH2_k127_7116847_0 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 402.0
WLSH2_k127_7116847_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 335.0
WLSH2_k127_7116847_2 methyltransferase - - - 0.0000000000000000002264 88.0
WLSH2_k127_7126038_0 Belongs to the peptidase M16 family K07263 - - 2.535e-209 659.0
WLSH2_k127_7126038_1 PFAM Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 562.0
WLSH2_k127_7126038_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000004776 243.0
WLSH2_k127_7126038_11 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000004056 222.0
WLSH2_k127_7126038_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
WLSH2_k127_7126038_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000003709 197.0
WLSH2_k127_7126038_14 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000003344 162.0
WLSH2_k127_7126038_15 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000004406 120.0
WLSH2_k127_7126038_2 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 492.0
WLSH2_k127_7126038_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 490.0
WLSH2_k127_7126038_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 466.0
WLSH2_k127_7126038_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 456.0
WLSH2_k127_7126038_6 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 344.0
WLSH2_k127_7126038_7 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 340.0
WLSH2_k127_7126038_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001358 283.0
WLSH2_k127_7126038_9 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
WLSH2_k127_7138426_0 penicillin-binding protein K05364 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 552.0
WLSH2_k127_7138426_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004134 239.0
WLSH2_k127_7157359_0 Circularly permuted ATP-grasp type 2 - - - 4.29e-235 734.0
WLSH2_k127_7157359_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 350.0
WLSH2_k127_7157359_2 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 336.0
WLSH2_k127_7157359_3 Proteasome subunit K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 286.0
WLSH2_k127_7157359_4 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009951 287.0
WLSH2_k127_7157359_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003253 253.0
WLSH2_k127_7157359_6 - - - - 0.000002092 49.0
WLSH2_k127_722654_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 2.27e-217 685.0
WLSH2_k127_722654_1 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 516.0
WLSH2_k127_722654_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 431.0
WLSH2_k127_722654_3 Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus K07261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 339.0
WLSH2_k127_722654_4 CoA-binding domain protein K09181 - - 0.0000003116 53.0
WLSH2_k127_7247209_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 326.0
WLSH2_k127_7247209_1 RibD C-terminal domain K00082,K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007296 275.0
WLSH2_k127_7247209_2 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000002992 213.0
WLSH2_k127_7247209_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000207 197.0
WLSH2_k127_7247209_4 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000001407 158.0
WLSH2_k127_7271528_0 PFAM Ribonuclease II K01147 - 3.1.13.1 1.469e-241 761.0
WLSH2_k127_7271528_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.766e-230 716.0
WLSH2_k127_7271528_10 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000001685 213.0
WLSH2_k127_7271528_11 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000004898 166.0
WLSH2_k127_7271528_12 acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000000006882 125.0
WLSH2_k127_7271528_13 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000234 110.0
WLSH2_k127_7271528_14 - - - - 0.000000000000000002226 87.0
WLSH2_k127_7271528_15 Rubrerythrin - - - 0.000000000000000009664 91.0
WLSH2_k127_7271528_2 zinc-transporting ATPase activity K03546,K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 381.0
WLSH2_k127_7271528_3 zinc-transporting ATPase activity K03546,K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 361.0
WLSH2_k127_7271528_4 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 310.0
WLSH2_k127_7271528_5 PFAM Cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 289.0
WLSH2_k127_7271528_6 Belongs to the SfsA family K06206 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009534 282.0
WLSH2_k127_7271528_7 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000001453 247.0
WLSH2_k127_7271528_8 Belongs to the DnaA family. HdA subfamily K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000001392 244.0
WLSH2_k127_7271528_9 Soluble lytic murein transglycosylase-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008564 231.0
WLSH2_k127_7287985_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1391.0
WLSH2_k127_7287985_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000482 247.0
WLSH2_k127_7287985_2 Na phosphate symporter K03324 - - 0.0000000000000000000000000000000000004263 146.0
WLSH2_k127_731753_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.593e-221 699.0
WLSH2_k127_731753_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 1.907e-195 618.0
WLSH2_k127_731753_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 536.0
WLSH2_k127_731753_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 504.0
WLSH2_k127_7364143_0 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K04652 GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0010467,GO:0016151,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 403.0
WLSH2_k127_7364143_1 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 304.0
WLSH2_k127_7364143_2 GGDEF domain - - - 0.000000000000000000000000000000000000000000008217 183.0
WLSH2_k127_7364143_3 PFAM Sulfatase - - - 0.00000000000000000000000000000000000001232 164.0
WLSH2_k127_7364143_4 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000007164 142.0
WLSH2_k127_7364143_5 protein conserved in bacteria - - - 0.000000000007635 68.0
WLSH2_k127_7364143_6 - - - - 0.00000948 50.0
WLSH2_k127_7386334_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1295.0
WLSH2_k127_7386334_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 538.0
WLSH2_k127_7386334_10 Thiamine-binding protein - - - 0.000000000000000000000000000000000001962 141.0
WLSH2_k127_7386334_11 - - - - 0.000000000000000000000000000001751 122.0
WLSH2_k127_7386334_12 - - - - 0.0000000004549 63.0
WLSH2_k127_7386334_2 pfam chad - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 482.0
WLSH2_k127_7386334_3 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 398.0
WLSH2_k127_7386334_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008549 362.0
WLSH2_k127_7386334_5 Cellulose biosynthesis protein BcsQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 346.0
WLSH2_k127_7386334_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 324.0
WLSH2_k127_7386334_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 294.0
WLSH2_k127_7386334_8 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000005877 261.0
WLSH2_k127_7386334_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004022 222.0
WLSH2_k127_7433183_0 PFAM Exonuclease K01141 - 3.1.11.1 6.94e-210 662.0
WLSH2_k127_7433183_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 402.0
WLSH2_k127_7433183_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000002377 230.0
WLSH2_k127_7433183_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000006936 199.0
WLSH2_k127_7433183_4 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000006682 142.0
WLSH2_k127_7433183_5 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000001519 127.0
WLSH2_k127_7465638_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 486.0
WLSH2_k127_7465638_1 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 471.0
WLSH2_k127_7465638_2 PFAM O-Antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 405.0
WLSH2_k127_7465638_3 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000004315 207.0
WLSH2_k127_7465638_4 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000003541 84.0
WLSH2_k127_7472008_0 CBS domain containing protein - - - 1.761e-221 698.0
WLSH2_k127_7472008_1 Citrate transporter - - - 2.122e-199 631.0
WLSH2_k127_7472008_2 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 560.0
WLSH2_k127_7472008_3 Hemolysins and related proteins containing CBS domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
WLSH2_k127_7472008_4 Transporter associated domain - - - 0.0000002278 55.0
WLSH2_k127_7497624_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1649.0
WLSH2_k127_7497624_1 ImcF-related N-terminal domain K11891 - - 0.0 1635.0
WLSH2_k127_7497624_10 Serine/threonine phosphatases, family 2C, catalytic domain K01090 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 307.0
WLSH2_k127_7497624_11 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007161 283.0
WLSH2_k127_7497624_13 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000003493 211.0
WLSH2_k127_7497624_14 TIGRFAM type VI secretion K11906 - - 0.00000000000000000000000000000000000000003184 156.0
WLSH2_k127_7497624_15 Belongs to the BolA IbaG family - - - 0.0000000000000000000000059 104.0
WLSH2_k127_7497624_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 9.701e-312 959.0
WLSH2_k127_7497624_3 Bacterial Type VI secretion, VC_A0110, EvfL, ImpJ, VasE K11893 - - 1.319e-229 716.0
WLSH2_k127_7497624_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 1.17e-198 622.0
WLSH2_k127_7497624_5 Type VI secretion system protein DotU K11892 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 600.0
WLSH2_k127_7497624_6 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 527.0
WLSH2_k127_7497624_7 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 470.0
WLSH2_k127_7497624_8 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 399.0
WLSH2_k127_7497624_9 Uncharacterized protein conserved in bacteria (DUF2094) K11890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 338.0
WLSH2_k127_7505353_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07644 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 447.0
WLSH2_k127_7505353_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 371.0
WLSH2_k127_7505353_2 biosynthesis protein ThiH K03150 - 4.1.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 338.0
WLSH2_k127_7505353_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000007943 255.0
WLSH2_k127_7505353_4 ThiF family K03148 - 2.7.7.73 0.0000000000000000000000000000000000000000001177 166.0
WLSH2_k127_7505353_5 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000000005336 165.0
WLSH2_k127_7505353_6 - - - - 0.0000000000000000000000000000000000413 139.0
WLSH2_k127_7505353_8 MgtC family K07507 - - 0.000000000000000000000000000006443 123.0
WLSH2_k127_7530815_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 477.0
WLSH2_k127_7530815_1 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001471 248.0
WLSH2_k127_7545263_0 alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 593.0
WLSH2_k127_7545263_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 472.0
WLSH2_k127_7545263_10 - - - - 0.00000000000000000000000000000000000000000000000000002559 198.0
WLSH2_k127_7545263_11 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000004249 146.0
WLSH2_k127_7545263_12 HEPN domain - - - 0.00000000000000000000000000001801 123.0
WLSH2_k127_7545263_13 HEPN domain - - - 0.0000000000001704 74.0
WLSH2_k127_7545263_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 439.0
WLSH2_k127_7545263_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 393.0
WLSH2_k127_7545263_4 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 397.0
WLSH2_k127_7545263_5 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 344.0
WLSH2_k127_7545263_6 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 301.0
WLSH2_k127_7545263_7 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
WLSH2_k127_7545263_8 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003743 256.0
WLSH2_k127_7545263_9 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000002805 256.0
WLSH2_k127_7581567_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.062e-263 814.0
WLSH2_k127_7581567_1 Domain of unknown function DUF87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 590.0
WLSH2_k127_7581567_2 TraB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 547.0
WLSH2_k127_7581567_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 298.0
WLSH2_k127_7581567_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000001568 262.0
WLSH2_k127_7581567_5 - - - - 0.0000000000000000000000000000000000000008689 154.0
WLSH2_k127_7628982_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1053.0
WLSH2_k127_7628982_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.422e-249 774.0
WLSH2_k127_7628982_2 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 454.0
WLSH2_k127_7631090_0 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 548.0
WLSH2_k127_7631090_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000002248 188.0
WLSH2_k127_7659607_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 586.0
WLSH2_k127_7659607_1 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 417.0
WLSH2_k127_7659607_2 FAD binding domain K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000001702 209.0
WLSH2_k127_769718_1 - - - - 0.00000000000000000000005153 105.0
WLSH2_k127_7733001_0 Cytochrome c-type biogenesis protein K02198 - - 4.8e-317 986.0
WLSH2_k127_7733001_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 419.0
WLSH2_k127_7733001_2 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 382.0
WLSH2_k127_7733001_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 339.0
WLSH2_k127_7733001_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 309.0
WLSH2_k127_7733001_5 TIGRFAM periplasmic protein K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000001323 231.0
WLSH2_k127_7733001_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000015 231.0
WLSH2_k127_7733001_7 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000000000000000002463 198.0
WLSH2_k127_7733001_8 pfam abc K01990 - - 0.00000000000000000000000000000000000000003252 154.0
WLSH2_k127_7733001_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000000004303 69.0
WLSH2_k127_7745222_0 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 528.0
WLSH2_k127_7745222_1 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 520.0
WLSH2_k127_7745222_2 BT1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 514.0
WLSH2_k127_7745222_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000006281 184.0
WLSH2_k127_7745222_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000004759 115.0
WLSH2_k127_7775612_0 small GTP-binding protein K02355 - - 0.0 1134.0
WLSH2_k127_7775612_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.921e-318 977.0
WLSH2_k127_7775612_10 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000005936 238.0
WLSH2_k127_7775612_11 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000004677 166.0
WLSH2_k127_7775612_12 Protein of unknown function (DUF2939) - - - 0.0000000000000000000000000000000000000000005345 162.0
WLSH2_k127_7775612_13 Membrane-flanked domain - - - 0.00000000000000000000000000000000000000003757 158.0
WLSH2_k127_7775612_14 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000000000000000006283 134.0
WLSH2_k127_7775612_16 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.0000000000000000000004586 100.0
WLSH2_k127_7775612_17 PFAM Paraquat-inducible protein A K03808 - - 0.0000000000008923 68.0
WLSH2_k127_7775612_18 - - - - 0.000000001173 62.0
WLSH2_k127_7775612_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.455e-294 915.0
WLSH2_k127_7775612_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 589.0
WLSH2_k127_7775612_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 539.0
WLSH2_k127_7775612_5 Transcriptional regulator K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 426.0
WLSH2_k127_7775612_6 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 404.0
WLSH2_k127_7775612_7 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 339.0
WLSH2_k127_7775612_8 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 297.0
WLSH2_k127_7775612_9 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000003023 245.0
WLSH2_k127_7790866_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 9.455e-228 711.0
WLSH2_k127_7790866_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 500.0
WLSH2_k127_7790866_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 373.0
WLSH2_k127_7790866_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 335.0
WLSH2_k127_7790866_4 CorA-like Mg2+ transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000301 272.0
WLSH2_k127_785631_0 PFAM Nickel-dependent hydrogenase, large subunit - - - 1.411e-261 814.0
WLSH2_k127_785631_1 NADH ubiquinone oxidoreductase K00122 - 1.17.1.9 1.699e-198 623.0
WLSH2_k127_785631_2 NADH ubiquinone oxidoreductase K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 384.0
WLSH2_k127_785631_3 PFAM NADH Ubiquinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 321.0
WLSH2_k127_785631_4 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000248 261.0
WLSH2_k127_785631_5 hydrogenase maturation protease - - - 0.00000000000000000000000000000002747 137.0
WLSH2_k127_7871890_0 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 372.0
WLSH2_k127_7871890_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 274.0
WLSH2_k127_7875185_0 modulator of DNA gyrase - - - 2.86e-224 704.0
WLSH2_k127_7875185_1 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 567.0
WLSH2_k127_7875185_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 449.0
WLSH2_k127_7875185_3 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 357.0
WLSH2_k127_7875185_4 PFAM L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000002317 205.0
WLSH2_k127_7884742_0 ABC transporter transmembrane region K06147 - - 9.28e-304 942.0
WLSH2_k127_7884742_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K01663 - - 7.038e-255 794.0
WLSH2_k127_7884742_10 Peptidase S24-like - - - 0.00000000000000000000000000000000000000000000009515 175.0
WLSH2_k127_7884742_11 - - - - 0.00000000000000000000000002924 115.0
WLSH2_k127_7884742_12 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000004206 94.0
WLSH2_k127_7884742_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.231e-237 738.0
WLSH2_k127_7884742_3 Histidine kinase K07673 - 2.7.13.3 4.635e-200 647.0
WLSH2_k127_7884742_4 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 531.0
WLSH2_k127_7884742_5 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 414.0
WLSH2_k127_7884742_6 response regulator receiver K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 306.0
WLSH2_k127_7884742_7 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000352 276.0
WLSH2_k127_7884742_8 PFAM Rhodanese-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002104 262.0
WLSH2_k127_7884742_9 - - - - 0.00000000000000000000000000000000000000000000008972 173.0
WLSH2_k127_788876_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 303.0
WLSH2_k127_788876_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 289.0
WLSH2_k127_788876_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.000000000000000000000000000000000000000000000000000004889 191.0
WLSH2_k127_7960699_0 SNARE associated Golgi protein - - - 0.0 1046.0
WLSH2_k127_7960699_1 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000317 246.0
WLSH2_k127_7960699_2 Domain of unknown function (DUF3368) - - - 0.0000000000000000000000000000000000000000002302 163.0
WLSH2_k127_7960699_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000114 127.0
WLSH2_k127_7960699_4 PFAM Uncharacterised protein family UPF0175 - - - 0.000000000000000000000001094 107.0
WLSH2_k127_7960699_5 Protein of unknown function (DUF3641) - - - 0.000000000000000001069 86.0
WLSH2_k127_7960699_6 Elongator protein 3, MiaB family, Radical SAM K06139 - - 0.0000000000000009979 76.0
WLSH2_k127_7960699_7 - - - - 0.00000000000003479 76.0
WLSH2_k127_7960699_9 Belongs to the 'phage' integrase family - - - 0.0000001454 55.0
WLSH2_k127_7967649_0 PFAM Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0 1062.0
WLSH2_k127_7967649_1 HAD-superfamily hydrolase, subfamily IIB K00696 - 2.4.1.14 0.0 1026.0
WLSH2_k127_7967649_2 lysine 2,3-aminomutase - - - 1.497e-219 688.0
WLSH2_k127_7967649_3 Putative transposase, YhgA-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 359.0
WLSH2_k127_7967649_4 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 353.0
WLSH2_k127_7967649_5 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 303.0
WLSH2_k127_7967649_6 PfkB domain protein K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 301.0
WLSH2_k127_8015926_0 PFAM transport-associated - - - 0.00000000000000000000000000000000000000001492 162.0
WLSH2_k127_8015926_1 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000001957 145.0
WLSH2_k127_8015926_2 PFAM LppC K07121 - - 0.000000000000000000000000000005357 126.0
WLSH2_k127_8019174_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1206.0
WLSH2_k127_8019174_1 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1159.0
WLSH2_k127_8019174_10 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 306.0
WLSH2_k127_8019174_11 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 303.0
WLSH2_k127_8019174_12 PFAM heat shock protein DnaJ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009517 267.0
WLSH2_k127_8019174_13 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002388 259.0
WLSH2_k127_8019174_14 HD domain K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000002046 247.0
WLSH2_k127_8019174_15 - - - - 0.000000000000000000000000000000000000000000000000000000000007811 211.0
WLSH2_k127_8019174_16 - - - - 0.00000000000000000000000000000000000000000000000000000001008 201.0
WLSH2_k127_8019174_17 PFAM Hemerythrin HHE - - - 0.00000000000000000000000000000000000000000000000000000452 196.0
WLSH2_k127_8019174_18 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000000000002106 183.0
WLSH2_k127_8019174_19 SnoaL-like domain - - - 0.000000000000000000000000000000000000000007444 160.0
WLSH2_k127_8019174_2 TIGRFAM DNA topoisomerase III K03169 - 5.99.1.2 0.0 1135.0
WLSH2_k127_8019174_20 H-NS histone family K03746 - - 0.000000000000000000000000000000000005383 141.0
WLSH2_k127_8019174_21 type IV pilus modification protein PilV - - - 0.00000000000000000000000000000001627 144.0
WLSH2_k127_8019174_22 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000006668 122.0
WLSH2_k127_8019174_23 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000002957 118.0
WLSH2_k127_8019174_24 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000006581 122.0
WLSH2_k127_8019174_26 Type II transport protein GspH K08084,K08085 - - 0.0000000000000000003713 93.0
WLSH2_k127_8019174_27 COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase - - - 0.0000000000000000142 85.0
WLSH2_k127_8019174_28 pilus assembly protein PilW - - - 0.000000000000002509 86.0
WLSH2_k127_8019174_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.005e-313 977.0
WLSH2_k127_8019174_4 Belongs to the glycosyl hydrolase 57 family - - - 3.093e-242 760.0
WLSH2_k127_8019174_5 Ion channel K10716 - - 1.36e-225 712.0
WLSH2_k127_8019174_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.771e-199 629.0
WLSH2_k127_8019174_7 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 524.0
WLSH2_k127_8019174_8 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 380.0
WLSH2_k127_8019174_9 Phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 368.0
WLSH2_k127_8083482_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 3.035e-316 987.0
WLSH2_k127_8083482_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 1.695e-298 932.0
WLSH2_k127_8083482_10 PFAM Pyruvate carboxyltransferase K01666 - 4.1.3.39 0.000000000000003885 76.0
WLSH2_k127_8083482_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.419e-282 904.0
WLSH2_k127_8083482_3 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 493.0
WLSH2_k127_8083482_4 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 407.0
WLSH2_k127_8083482_5 PFAM Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 389.0
WLSH2_k127_8083482_6 subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 287.0
WLSH2_k127_8083482_7 low molecular weight K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000001748 238.0
WLSH2_k127_8083482_8 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000002113 176.0
WLSH2_k127_8083482_9 - - - - 0.0000000000000000000000000000000003087 135.0
WLSH2_k127_8101971_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1652.0
WLSH2_k127_8101971_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 493.0
WLSH2_k127_8101971_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000002543 263.0
WLSH2_k127_8101971_3 deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000115 211.0
WLSH2_k127_8146134_0 Domain of unknown function (DUF697) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 527.0
WLSH2_k127_8146134_1 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 486.0
WLSH2_k127_8146134_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00003175 51.0
WLSH2_k127_8146134_2 50S ribosome-binding GTPase K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 424.0
WLSH2_k127_8146134_3 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 306.0
WLSH2_k127_8146134_4 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 307.0
WLSH2_k127_8146134_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 288.0
WLSH2_k127_8146134_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000318 275.0
WLSH2_k127_8146134_7 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000177 242.0
WLSH2_k127_8146134_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000002579 182.0
WLSH2_k127_8146134_9 TIGRFAM Addiction module toxin, RelE StbE K06218 - - 0.00000000000000000000000000000003021 130.0
WLSH2_k127_8181539_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.766e-221 701.0
WLSH2_k127_8181539_1 glutamate--cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 564.0
WLSH2_k127_8181539_2 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 481.0
WLSH2_k127_8181539_3 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 370.0
WLSH2_k127_8181539_4 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000000000000000002123 197.0
WLSH2_k127_8181539_5 PFAM aminotransferase class V - - - 0.00000000152 60.0
WLSH2_k127_8199844_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 573.0
WLSH2_k127_8199844_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0019808,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 387.0
WLSH2_k127_8199844_2 PFAM binding-protein-dependent transport systems inner membrane component K11071,K11075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 321.0
WLSH2_k127_8206232_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1985.0
WLSH2_k127_8206232_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1345.0
WLSH2_k127_8206232_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006804 258.0
WLSH2_k127_8206232_11 ATP cone domain K05715 - - 0.00000000000000000000000000000000000000000000009654 186.0
WLSH2_k127_8206232_12 Response regulator receiver domain - - - 0.00000000000000000000000000000001987 134.0
WLSH2_k127_8206232_13 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000000000000000000000000001738 119.0
WLSH2_k127_8206232_14 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000001038 91.0
WLSH2_k127_8206232_15 Belongs to the ompA family K03286 - - 0.000000000000001696 78.0
WLSH2_k127_8206232_16 PFAM NapD family protein K02570 - - 0.0000000000008787 72.0
WLSH2_k127_8206232_17 EamA-like transporter family - - - 0.0008316 44.0
WLSH2_k127_8206232_2 Spermine/spermidine synthase domain K00797 - 2.5.1.16 2.124e-294 924.0
WLSH2_k127_8206232_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 493.0
WLSH2_k127_8206232_4 TIGRFAM ferredoxin-type protein, NapH MauN family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 411.0
WLSH2_k127_8206232_5 MauM NapG family ferredoxin-type protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 405.0
WLSH2_k127_8206232_6 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 371.0
WLSH2_k127_8206232_7 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 300.0
WLSH2_k127_8206232_8 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
WLSH2_k127_8206232_9 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
WLSH2_k127_8235170_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.552e-244 772.0
WLSH2_k127_8235170_1 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 600.0
WLSH2_k127_8235170_2 peptidase S16, lon K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001526 248.0
WLSH2_k127_8235170_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000008425 119.0
WLSH2_k127_8241494_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.614e-255 801.0
WLSH2_k127_8241494_1 (C AC39) subunit K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 397.0
WLSH2_k127_8241494_2 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000000000000000000000000000000000007221 222.0
WLSH2_k127_8241494_3 V-type proton ATPase subunit E K02121 - - 0.000000000000000000000000000000000000000000000000000000002008 206.0
WLSH2_k127_8241494_4 - - - - 0.000000000000000000000000000000000001951 140.0
WLSH2_k127_8241494_5 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.000000000000000000000000000000000667 133.0
WLSH2_k127_8241494_6 Putative zinc- or iron-chelating domain K09160 - - 0.00000000001141 65.0
WLSH2_k127_8266526_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.509e-218 680.0
WLSH2_k127_8266526_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 297.0
WLSH2_k127_828377_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1162.0
WLSH2_k127_828377_1 4Fe-4S dicluster domain - - - 1.697e-305 939.0
WLSH2_k127_828377_10 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 611.0
WLSH2_k127_828377_11 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 568.0
WLSH2_k127_828377_12 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 484.0
WLSH2_k127_828377_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 452.0
WLSH2_k127_828377_14 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 428.0
WLSH2_k127_828377_15 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 412.0
WLSH2_k127_828377_16 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 403.0
WLSH2_k127_828377_17 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 387.0
WLSH2_k127_828377_18 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 379.0
WLSH2_k127_828377_19 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 376.0
WLSH2_k127_828377_2 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.101e-270 833.0
WLSH2_k127_828377_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 334.0
WLSH2_k127_828377_21 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 323.0
WLSH2_k127_828377_22 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 333.0
WLSH2_k127_828377_23 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 304.0
WLSH2_k127_828377_24 TIGRFAM CRISPR-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 291.0
WLSH2_k127_828377_25 TIGRFAM sulfur relay protein TusD DsrE K07235 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000145 255.0
WLSH2_k127_828377_26 Belongs to the DsrF TusC family K07236 - - 0.00000000000000000000000000000000000000000000000000000000000000000001025 235.0
WLSH2_k127_828377_27 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
WLSH2_k127_828377_28 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000268 228.0
WLSH2_k127_828377_29 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000002883 222.0
WLSH2_k127_828377_3 Belongs to the GPI family K01810 - 5.3.1.9 2.281e-262 818.0
WLSH2_k127_828377_30 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000000000000000000000000001286 218.0
WLSH2_k127_828377_31 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000008449 204.0
WLSH2_k127_828377_32 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000003298 192.0
WLSH2_k127_828377_33 - - - - 0.00000000000000000000000000000000000000000000002102 178.0
WLSH2_k127_828377_34 sulfur relay protein TusB DsrH K07237 - - 0.000000000000000000000000000000000000000000005261 165.0
WLSH2_k127_828377_35 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000005489 159.0
WLSH2_k127_828377_36 signal sequence binding - - - 0.0000000000000000000000000000000000000001718 158.0
WLSH2_k127_828377_37 - - - - 0.00000000000000000000000000000000000000211 155.0
WLSH2_k127_828377_38 - - - - 0.00000000000000000000000000000000000001676 154.0
WLSH2_k127_828377_39 - - - - 0.0000000000000000000000000008172 113.0
WLSH2_k127_828377_4 reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 1.794e-238 737.0
WLSH2_k127_828377_40 Protein of unknown function (DUF2288) - - - 0.00000000000000000000000001119 114.0
WLSH2_k127_828377_41 OsmC-like protein K07397 - - 0.0000000000001722 70.0
WLSH2_k127_828377_42 TIGRFAM Nucleotidyltransferase substrate binding protein, HI0074 - - - 0.00000000115 60.0
WLSH2_k127_828377_5 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 3.36e-228 713.0
WLSH2_k127_828377_6 PFAM SNARE associated Golgi protein K03975 - - 1.354e-224 715.0
WLSH2_k127_828377_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.226e-215 680.0
WLSH2_k127_828377_8 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 2.612e-199 632.0
WLSH2_k127_828377_9 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 3.529e-196 629.0
WLSH2_k127_8297437_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0 1227.0
WLSH2_k127_8297437_1 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.0000000000000000000000000000000000000000000000000003072 188.0
WLSH2_k127_8297437_2 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000133 102.0
WLSH2_k127_8297437_3 Transport and Golgi organisation 2 - - - 0.00000000000000000005235 92.0
WLSH2_k127_8404625_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K07309,K07310,K07811,K07812,K08351 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009033,GO:0009055,GO:0009060,GO:0009061,GO:0009322,GO:0009390,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016657,GO:0016661,GO:0016662,GO:0016667,GO:0016671,GO:0022900,GO:0030151,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0032991,GO:0033744,GO:0033797,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0050626,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.7.2.3,1.8.5.3,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 492.0
WLSH2_k127_8404625_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 312.0
WLSH2_k127_842759_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1039.0
WLSH2_k127_842759_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.371e-252 785.0
WLSH2_k127_842759_2 major facilitator superfamily K08218 - - 2.516e-216 686.0
WLSH2_k127_842759_3 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 479.0
WLSH2_k127_842759_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 393.0
WLSH2_k127_842759_5 Succinate dehydrogenase hydrophobic membrane anchor K00242 - - 0.000000000000000000000000001071 121.0
WLSH2_k127_842759_6 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000002548 112.0
WLSH2_k127_844545_0 AcrB/AcrD/AcrF family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 520.0
WLSH2_k127_844545_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 366.0
WLSH2_k127_844545_2 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 321.0
WLSH2_k127_844545_3 5'-nucleotidase, C-terminal domain K17224 - - 0.00000000000000000001062 92.0
WLSH2_k127_8456527_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1359.0
WLSH2_k127_8456527_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 8.553e-251 786.0
WLSH2_k127_8456527_10 DNA RNA helicase - - - 0.0000001331 55.0
WLSH2_k127_8456527_2 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 1.678e-228 716.0
WLSH2_k127_8456527_3 TIGRFAM ATP phosphoribosyltransferase, C-terminal domain K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 464.0
WLSH2_k127_8456527_4 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 328.0
WLSH2_k127_8456527_5 Oxidoreductase FAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 304.0
WLSH2_k127_8456527_6 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000000009464 187.0
WLSH2_k127_8456527_7 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000000000001049 139.0
WLSH2_k127_8456527_8 RNA recognition motif - - - 0.00000000000000000000000000000000003538 138.0
WLSH2_k127_8456527_9 PFAM RNA recognition motif - - - 0.0000000000000001418 83.0
WLSH2_k127_8499313_0 Cysteine-rich domain - - - 2.324e-227 710.0
WLSH2_k127_8499313_1 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009228 259.0
WLSH2_k127_8499313_2 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000004132 214.0
WLSH2_k127_8517905_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 419.0
WLSH2_k127_8517905_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000002183 203.0
WLSH2_k127_8566117_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 305.0
WLSH2_k127_8566117_1 PFAM Cyclic nucleotide-binding K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005482 277.0
WLSH2_k127_8578273_0 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 461.0
WLSH2_k127_8578273_1 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 379.0
WLSH2_k127_8578273_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000002752 92.0
WLSH2_k127_8581060_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 5.265e-278 873.0
WLSH2_k127_8581060_1 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 1.018e-222 701.0
WLSH2_k127_8581060_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 482.0
WLSH2_k127_8581060_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 477.0
WLSH2_k127_8581060_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 325.0
WLSH2_k127_8581060_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 271.0
WLSH2_k127_8581060_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000001316 265.0
WLSH2_k127_8581060_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000002515 236.0
WLSH2_k127_8581060_8 PFAM Amino acid-binding ACT K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000001449 230.0
WLSH2_k127_8581060_9 Phosphoglycerate mutase family K02226,K15634 - 3.1.3.73,5.4.2.12 0.0000000000000000000000000000000000000000000000000000000001924 217.0
WLSH2_k127_868465_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 2.304e-264 820.0
WLSH2_k127_868465_1 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000001549 146.0
WLSH2_k127_869966_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.444e-278 866.0
WLSH2_k127_869966_1 Malate synthase K01638 - 2.3.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 441.0
WLSH2_k127_869966_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000002454 252.0
WLSH2_k127_869966_3 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000006539 244.0
WLSH2_k127_8719339_0 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 338.0
WLSH2_k127_8719339_1 FAD dependent oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 301.0
WLSH2_k127_8719339_2 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
WLSH2_k127_8719339_3 Protein of unknown function (DUF2878) - - - 0.0000000000000000000000000000001311 134.0
WLSH2_k127_8719339_4 COG2230 Cyclopropane fatty acid synthase and related K00574 - 2.1.1.79 0.0000000000000000000003402 96.0
WLSH2_k127_8722724_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.697e-237 739.0
WLSH2_k127_8722724_1 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.8.2.3 0.0000000000000000000000000000000000000000000000000000000000000000001273 233.0
WLSH2_k127_8722724_2 PFAM Sulphatase-modifying factor K20333 - - 0.00000000000000000000000000000000000000000000000000000002939 210.0
WLSH2_k127_8722724_3 oxygen carrier activity K07216 - - 0.000000000000000000000000000009659 125.0
WLSH2_k127_8722724_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000004539 94.0
WLSH2_k127_8743592_0 PFAM porin Gram-negative type - - - 0.00000000000000000000000000000000000000000000000000000000000006455 227.0
WLSH2_k127_8743592_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.0000000000000000000000004739 109.0
WLSH2_k127_8760723_0 PFAM MazG nucleotide pyrophosphohydrolase K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 264.0
WLSH2_k127_8760723_1 - - - - 0.000000000000000000000000000000000000006345 147.0
WLSH2_k127_8760723_2 CoA binding domain K06929 - - 0.000000000000000000000000000000000001234 145.0
WLSH2_k127_8762808_0 sulphate transporter K03321 - - 1.264e-267 830.0
WLSH2_k127_8762808_1 TIGRFAM Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 383.0
WLSH2_k127_8762808_2 molybdenum ABC transporter, periplasmic K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 349.0
WLSH2_k127_8762808_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000004222 258.0
WLSH2_k127_8762808_4 TOBE domain K02019 - - 0.0000000000000002588 81.0
WLSH2_k127_8762808_5 ModE family transcriptional regulator K02019 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000002274 79.0
WLSH2_k127_8768408_0 Sodium:sulfate symporter transmembrane region - - - 5.274e-251 789.0
WLSH2_k127_8768408_1 Citrate transporter - - - 1.328e-218 687.0
WLSH2_k127_8768408_10 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000000000000000000000000000000004327 179.0
WLSH2_k127_8768408_11 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000005986 136.0
WLSH2_k127_8768408_12 - - - - 0.000000000000000000000000000004927 125.0
WLSH2_k127_8768408_13 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000858 108.0
WLSH2_k127_8768408_14 Glycine zipper - - - 0.00000000000000000000184 96.0
WLSH2_k127_8768408_15 Polycystin cation channel K08714 - - 0.0000000000003125 73.0
WLSH2_k127_8768408_16 Transposase IS200 like K07491 - - 0.00002315 47.0
WLSH2_k127_8768408_17 Glycosyl transferase family group 2 - - - 0.000176 44.0
WLSH2_k127_8768408_2 Involved in arsenical resistance. Thought to form the channel of an arsenite pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 602.0
WLSH2_k127_8768408_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 499.0
WLSH2_k127_8768408_4 PFAM Uncharacterised protein family UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 418.0
WLSH2_k127_8768408_5 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 385.0
WLSH2_k127_8768408_6 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 375.0
WLSH2_k127_8768408_7 Ceramidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000194 236.0
WLSH2_k127_8768408_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000003421 203.0
WLSH2_k127_8768408_9 Protein of unknown function (DUF3611) - - - 0.0000000000000000000000000000000000000000000000002452 183.0
WLSH2_k127_8772906_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1828.0
WLSH2_k127_8772906_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.158e-262 814.0
WLSH2_k127_8772906_2 Belongs to the CarA family K01956 - 6.3.5.5 3.366e-199 627.0
WLSH2_k127_8772906_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 595.0
WLSH2_k127_8772906_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 495.0
WLSH2_k127_8772906_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 343.0
WLSH2_k127_8772906_6 PFAM Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000855 271.0
WLSH2_k127_8772906_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001234 250.0
WLSH2_k127_8772906_8 TIGRFAM Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000004079 229.0
WLSH2_k127_8772906_9 FimV C-terminal K08086 - - 0.00000000000000000000000000000000005356 140.0
WLSH2_k127_8817177_0 COG0474 Cation transport ATPase - - - 0.0 1406.0
WLSH2_k127_8817177_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1134.0
WLSH2_k127_8817177_10 Na+/H+ ion antiporter subunit K05569 - - 0.000000000000000000000000003769 116.0
WLSH2_k127_8817177_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000002062 108.0
WLSH2_k127_8817177_12 Domain of unknown function (DUF4040) K05566 - - 0.00000000000000000000003144 102.0
WLSH2_k127_8817177_13 COG COG2212 Multisubunit Na H antiporter MnhF subunit Inorganic ion transport and metabolism K05570 - - 0.0000000000000001692 85.0
WLSH2_k127_8817177_14 Belongs to the 'phage' integrase family - - - 0.00000000002605 66.0
WLSH2_k127_8817177_15 PIN domain - - - 0.0000000002397 63.0
WLSH2_k127_8817177_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 7.528e-209 666.0
WLSH2_k127_8817177_3 PFAM NADH Ubiquinone plastoquinone K05568 - - 8.772e-198 628.0
WLSH2_k127_8817177_4 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 535.0
WLSH2_k127_8817177_5 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 415.0
WLSH2_k127_8817177_6 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 407.0
WLSH2_k127_8817177_7 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 349.0
WLSH2_k127_8817177_8 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.000000000000000000000000000000000003419 150.0
WLSH2_k127_8817177_9 PFAM Na H antiporter subunit K05571 - - 0.000000000000000000000000001568 115.0
WLSH2_k127_8838779_0 type iii restriction K01156 - 3.1.21.5 4.04e-281 878.0
WLSH2_k127_8838779_1 Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 440.0
WLSH2_k127_8838779_2 Acetyltransferase (GNAT) domain - - - 0.0002817 44.0
WLSH2_k127_8863408_0 BT1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 451.0
WLSH2_k127_8863408_1 - - - - 0.00000000000000000000000001375 117.0
WLSH2_k127_8900092_0 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 578.0
WLSH2_k127_8900092_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 394.0
WLSH2_k127_8900092_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000002883 222.0
WLSH2_k127_9013688_0 cation transport ATPase K01533 - 3.6.3.4 0.0 1110.0
WLSH2_k127_9013688_1 Histidine kinase K02482,K14986 - 2.7.13.3 2.455e-313 981.0
WLSH2_k127_9013688_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 368.0
WLSH2_k127_9013688_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 377.0
WLSH2_k127_9013688_12 Permease YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 364.0
WLSH2_k127_9013688_13 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 329.0
WLSH2_k127_9013688_14 pfam chad - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 318.0
WLSH2_k127_9013688_15 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 294.0
WLSH2_k127_9013688_16 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001239 278.0
WLSH2_k127_9013688_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001823 280.0
WLSH2_k127_9013688_18 PFAM FixH - - - 0.00000000000000000000000000000000000000000000000000000003424 208.0
WLSH2_k127_9013688_19 PFAM DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000004459 199.0
WLSH2_k127_9013688_2 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 4.214e-295 915.0
WLSH2_k127_9013688_20 response regulator receiver K13041 - - 0.00000000000000000000000000000000000000000000000000000005051 198.0
WLSH2_k127_9013688_21 pfam rdd - - - 0.000000000000000000000000000000000000602 153.0
WLSH2_k127_9013688_22 Cytochrome oxidase maturation protein - - - 0.000000000000000000001718 95.0
WLSH2_k127_9013688_23 Cbb3-type cytochrome oxidase component FixQ - - - 0.000000000000000000004043 94.0
WLSH2_k127_9013688_24 - - - - 0.0000001288 54.0
WLSH2_k127_9013688_25 Putative ATP-dependent Lon protease K01338 - 3.4.21.53 0.00001435 52.0
WLSH2_k127_9013688_3 TIGRFAM cytochrome c oxidase accessory protein - - - 6.359e-234 731.0
WLSH2_k127_9013688_4 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.083e-221 691.0
WLSH2_k127_9013688_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 4.877e-216 681.0
WLSH2_k127_9013688_6 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 457.0
WLSH2_k127_9013688_7 PFAM Cytochrome C oxidase, monoheme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 430.0
WLSH2_k127_9013688_8 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 400.0
WLSH2_k127_9013688_9 Pirin C-terminal cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 384.0
WLSH2_k127_904266_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 497.0
WLSH2_k127_904266_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 376.0
WLSH2_k127_9057156_0 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000001516 220.0
WLSH2_k127_9057156_1 Adenylate cyclase - - - 0.0000000000000000000000000000000006644 139.0
WLSH2_k127_9057156_2 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0000000000001021 75.0
WLSH2_k127_9117058_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K21134 - - 1.603e-208 660.0
WLSH2_k127_9123431_0 ABC transporter - - - 0.0 1046.0
WLSH2_k127_9123431_1 ATPase (AAA superfamily) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 313.0
WLSH2_k127_9123431_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000001183 121.0
WLSH2_k127_9124678_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1189.0
WLSH2_k127_9124678_1 PFAM UMUC domain protein DNA-repair protein K03502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 482.0
WLSH2_k127_9124678_2 Belongs to the peptidase S24 family K03503 - - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
WLSH2_k127_9159047_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 297.0
WLSH2_k127_9159047_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 281.0
WLSH2_k127_9159047_2 Domain of unknown function (DUF4426) - - - 0.00000000000000000000000000000008672 129.0
WLSH2_k127_9257913_0 PFAM von Willebrand factor type A - - - 0.0 1233.0
WLSH2_k127_9257913_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 8.32e-284 874.0
WLSH2_k127_9257913_2 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 488.0
WLSH2_k127_9257913_3 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000003287 229.0
WLSH2_k127_9257913_4 AAA-ATPase - - - 0.000000000000000000000000000000000000000000000000000001421 199.0
WLSH2_k127_9257913_5 PFAM GTP-binding protein HSR1-related K06946 - - 0.00000000000000000000000000000000000000000000008119 171.0
WLSH2_k127_9257913_6 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000002654 68.0
WLSH2_k127_9257913_7 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.00000002365 59.0
WLSH2_k127_9264257_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 3.814e-275 851.0
WLSH2_k127_9294157_0 PFAM Alpha-2-macroglobulin K06894 - - 5.646e-264 830.0
WLSH2_k127_9299497_0 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 460.0
WLSH2_k127_9299497_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 441.0
WLSH2_k127_9299497_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000001007 112.0
WLSH2_k127_9299497_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000001857 90.0
WLSH2_k127_9314381_0 homoserine dehydrogenase K00003 - 1.1.1.3 4e-237 739.0
WLSH2_k127_9314381_1 aminotransferase class I and II K14261 - - 2.446e-235 731.0
WLSH2_k127_9314381_10 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000000001942 182.0
WLSH2_k127_9314381_11 Belongs to the ArsC family - - - 0.0000000000000000000000000000000000000000000000001059 179.0
WLSH2_k127_9314381_12 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000001251 174.0
WLSH2_k127_9314381_13 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000002402 170.0
WLSH2_k127_9314381_14 - - - - 0.000000000000000000000000000000000000002211 154.0
WLSH2_k127_9314381_15 Belongs to the pirin family K06911 - - 0.00000000000000000000000005046 113.0
WLSH2_k127_9314381_16 - K19168 - - 0.0000000000000000000000004197 110.0
WLSH2_k127_9314381_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000002771 109.0
WLSH2_k127_9314381_18 Phage integrase, N-terminal SAM-like domain - - - 0.00000000001179 68.0
WLSH2_k127_9314381_2 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 591.0
WLSH2_k127_9314381_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 572.0
WLSH2_k127_9314381_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 551.0
WLSH2_k127_9314381_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 502.0
WLSH2_k127_9314381_6 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 434.0
WLSH2_k127_9314381_7 Pfam Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 400.0
WLSH2_k127_9314381_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001857 264.0
WLSH2_k127_9314381_9 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
WLSH2_k127_9363946_0 lipid catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 404.0
WLSH2_k127_9363946_1 DUF1704 - - - 0.000000000000000000000000000000000000000001746 156.0
WLSH2_k127_9363946_2 Sulfate permease family - - - 0.0000000008855 65.0
WLSH2_k127_9363946_3 transposase activity - - - 0.000001735 54.0
WLSH2_k127_9421932_0 S1, RNA binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 481.0
WLSH2_k127_9421932_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 336.0
WLSH2_k127_9421932_2 subfamily IA, variant 1 K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000000000000007276 183.0
WLSH2_k127_9430908_0 PFAM Archaeal ATPase - - - 3.038e-224 706.0
WLSH2_k127_9430908_1 PFAM methyltransferase small - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 306.0
WLSH2_k127_9430908_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000002488 196.0
WLSH2_k127_9430908_3 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000001564 90.0
WLSH2_k127_94739_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 3.638e-222 694.0
WLSH2_k127_94739_1 - - - - 1.71e-220 696.0
WLSH2_k127_94739_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 508.0
WLSH2_k127_94739_11 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 473.0
WLSH2_k127_94739_12 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 469.0
WLSH2_k127_94739_13 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009382 464.0
WLSH2_k127_94739_14 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 450.0
WLSH2_k127_94739_15 D-Ala-D-Ala carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 440.0
WLSH2_k127_94739_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 420.0
WLSH2_k127_94739_17 TIGRFAM Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 413.0
WLSH2_k127_94739_18 PFAM ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 404.0
WLSH2_k127_94739_19 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 396.0
WLSH2_k127_94739_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.645e-217 693.0
WLSH2_k127_94739_20 TIGRFAM acetoacetyl-CoA reductase K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 392.0
WLSH2_k127_94739_21 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 376.0
WLSH2_k127_94739_22 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 378.0
WLSH2_k127_94739_23 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 368.0
WLSH2_k127_94739_24 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 353.0
WLSH2_k127_94739_25 Trypsin-like serine protease with C-terminal PDZ domain K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 317.0
WLSH2_k127_94739_26 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 315.0
WLSH2_k127_94739_27 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000002277 259.0
WLSH2_k127_94739_28 PFAM toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006085 254.0
WLSH2_k127_94739_29 PFAM CreA K05805 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
WLSH2_k127_94739_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.528e-214 670.0
WLSH2_k127_94739_30 TIGRFAM Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.000000000000000000000000000000000000000000000000000000000000001083 224.0
WLSH2_k127_94739_31 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000003048 220.0
WLSH2_k127_94739_32 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000000000597 191.0
WLSH2_k127_94739_33 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001921 173.0
WLSH2_k127_94739_34 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000001951 166.0
WLSH2_k127_94739_35 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000000000001991 161.0
WLSH2_k127_94739_36 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.0000000000000000000000000000000000000000237 161.0
WLSH2_k127_94739_37 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000002963 150.0
WLSH2_k127_94739_38 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000000004752 157.0
WLSH2_k127_94739_39 Domain of unknown function (DUF1840) - - - 0.00000000000000000000000000000000001372 138.0
WLSH2_k127_94739_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.324e-210 660.0
WLSH2_k127_94739_40 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000007647 143.0
WLSH2_k127_94739_41 Phosphotransferase System K11189 - - 0.000000000000000000000000000003459 125.0
WLSH2_k127_94739_42 Phasin protein - - - 0.000000000000000000000000000006721 123.0
WLSH2_k127_94739_43 PFAM transport-associated - - - 0.00000000000000000000000000003846 121.0
WLSH2_k127_94739_44 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000178 112.0
WLSH2_k127_94739_45 Membrane - - - 0.00000000000000000000004471 105.0
WLSH2_k127_94739_46 domain, Protein K03112 - - 0.00000000000000000001821 105.0
WLSH2_k127_94739_47 NTP binding protein (Contains STAS domain) K07122 - - 0.0000000000000000008594 89.0
WLSH2_k127_94739_48 Prokaryotic lipoprotein-attachment site - - - 0.000000005121 62.0
WLSH2_k127_94739_49 - - - - 0.000104 48.0
WLSH2_k127_94739_5 PFAM FAD linked oxidase domain protein K03777 - 1.1.5.12 5.366e-208 657.0
WLSH2_k127_94739_6 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 5.528e-202 631.0
WLSH2_k127_94739_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 586.0
WLSH2_k127_94739_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 578.0
WLSH2_k127_94739_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 530.0
WLSH2_k127_950895_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 3.409e-293 910.0
WLSH2_k127_950895_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 1.085e-223 700.0
WLSH2_k127_950895_10 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006717 250.0
WLSH2_k127_950895_11 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
WLSH2_k127_950895_12 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000001292 222.0
WLSH2_k127_950895_13 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000000000009314 211.0
WLSH2_k127_950895_14 ferredoxin, 2Fe-2S K04755 - - 0.00000000000000000000000000000000000000000000000000000000004211 205.0
WLSH2_k127_950895_15 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000005329 206.0
WLSH2_k127_950895_16 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.0000000000000000000000000000000000000000000000001065 183.0
WLSH2_k127_950895_17 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000001328 189.0
WLSH2_k127_950895_18 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K05997,K13628 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016530,GO:0019538,GO:0022607,GO:0031163,GO:0034986,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051604,GO:0071704,GO:0071840,GO:0097428,GO:0140104,GO:1901564 - 0.0000000000000000000000000000000000000000000000001706 178.0
WLSH2_k127_950895_19 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000001357 130.0
WLSH2_k127_950895_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 5.239e-198 629.0
WLSH2_k127_950895_20 Iron-sulphur cluster assembly - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000006118 112.0
WLSH2_k127_950895_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 571.0
WLSH2_k127_950895_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 531.0
WLSH2_k127_950895_5 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 419.0
WLSH2_k127_950895_6 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 414.0
WLSH2_k127_950895_7 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 423.0
WLSH2_k127_950895_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 371.0
WLSH2_k127_950895_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 310.0
WLSH2_k127_9527996_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1114.0
WLSH2_k127_9527996_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1083.0
WLSH2_k127_9527996_2 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 6.478e-252 794.0
WLSH2_k127_9527996_3 pfam abc K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 366.0
WLSH2_k127_9527996_4 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000000000000000000000000000000001719 155.0
WLSH2_k127_9566030_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.605e-319 986.0
WLSH2_k127_9566030_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.388e-295 909.0
WLSH2_k127_9566030_10 Putative inner membrane protein (DUF1819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 298.0
WLSH2_k127_9566030_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005227 284.0
WLSH2_k127_9566030_12 Domain of unknown function (DUF1788) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006985 253.0
WLSH2_k127_9566030_13 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000004706 242.0
WLSH2_k127_9566030_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000000000000001151 228.0
WLSH2_k127_9566030_15 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000008624 220.0
WLSH2_k127_9566030_16 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000003014 213.0
WLSH2_k127_9566030_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000007081 215.0
WLSH2_k127_9566030_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000006711 132.0
WLSH2_k127_9566030_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.265e-292 906.0
WLSH2_k127_9566030_20 ATP synthase I chain K02116 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00002606 52.0
WLSH2_k127_9566030_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.238e-266 823.0
WLSH2_k127_9566030_4 RNA-binding protein homologous to eukaryotic snRNP - - - 3.456e-244 773.0
WLSH2_k127_9566030_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 3.755e-201 636.0
WLSH2_k127_9566030_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 461.0
WLSH2_k127_9566030_7 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 440.0
WLSH2_k127_9566030_8 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 406.0
WLSH2_k127_9566030_9 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 392.0
WLSH2_k127_9601444_0 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 541.0
WLSH2_k127_9601444_1 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 336.0
WLSH2_k127_9601444_2 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009516 271.0
WLSH2_k127_9601444_3 - - - - 0.000000000000000000000000000000000000000000000000000001876 195.0
WLSH2_k127_9601444_4 Part of a membrane complex involved in electron transport K03616 - - 0.000000002678 61.0
WLSH2_k127_9641988_0 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 480.0
WLSH2_k127_9641988_1 Prokaryotic diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000001002 172.0
WLSH2_k127_9641988_2 TIGRFAM small redox-active disulfide protein 2 - - - 0.00000000000000000000000000000003532 128.0
WLSH2_k127_9641988_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000004216 119.0
WLSH2_k127_9641988_4 TIGRFAM Arsenical-resistance protein K03325 - - 0.0000000000000000000000002989 109.0
WLSH2_k127_9641988_5 permease K07089 - - 0.00000003371 58.0
WLSH2_k127_9641988_6 Major Facilitator Superfamily - - - 0.000134 44.0
WLSH2_k127_9672131_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.792e-205 647.0
WLSH2_k127_9672131_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 401.0
WLSH2_k127_9672131_2 DDE_Tnp_1-associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 395.0
WLSH2_k127_9672131_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
WLSH2_k127_9672131_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000004028 250.0
WLSH2_k127_9672131_5 Transposase DDE domain - - - 0.00000000000000000000000000000000002879 145.0
WLSH2_k127_9686643_0 protein conserved in bacteria K09800 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - 1.073e-270 881.0
WLSH2_k127_9686643_1 Surface antigen variable number K07278 - - 9.175e-199 639.0
WLSH2_k127_9686643_10 PFAM Cupin 2, conserved barrel K11312 - - 0.000000000000000000000000000000009167 134.0
WLSH2_k127_9686643_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000001006 115.0
WLSH2_k127_9686643_12 - - - - 0.000000000000000000000004738 108.0
WLSH2_k127_9686643_13 long-chain fatty acid transport protein - - - 0.00000000000000008561 83.0
WLSH2_k127_9686643_14 PFAM Integrase catalytic - - - 0.000000000000007886 81.0
WLSH2_k127_9686643_2 Tetratricopeptide repeat - - - 1.621e-194 626.0
WLSH2_k127_9686643_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 541.0
WLSH2_k127_9686643_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 512.0
WLSH2_k127_9686643_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 405.0
WLSH2_k127_9686643_6 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000932 387.0
WLSH2_k127_9686643_7 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 356.0
WLSH2_k127_9686643_8 Belongs to the thioredoxin family K05838 - - 0.0000000000000000000000000000000000000000000001453 174.0
WLSH2_k127_9686643_9 - - - - 0.000000000000000000000000000000002157 132.0
WLSH2_k127_9708124_0 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 336.0
WLSH2_k127_9708124_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000001505 244.0
WLSH2_k127_9708124_2 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000004532 230.0
WLSH2_k127_9714685_0 Phosphatidylinositol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 368.0
WLSH2_k127_9714685_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
WLSH2_k127_9714685_2 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004264 271.0
WLSH2_k127_9714685_3 Domain of unknown function (DUF4338) - - - 0.00000000000000001698 81.0
WLSH2_k127_9714685_4 transmembrane transporter activity K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000003612 54.0
WLSH2_k127_978078_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 9.662e-278 859.0
WLSH2_k127_978078_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 9.331e-267 838.0
WLSH2_k127_978078_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 557.0
WLSH2_k127_978078_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 491.0
WLSH2_k127_978078_4 signal transduction histidine kinase K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 468.0
WLSH2_k127_978078_5 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
WLSH2_k127_978078_6 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000004145 95.0
WLSH2_k127_978078_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001161 55.0
WLSH2_k127_980945_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 444.0
WLSH2_k127_980945_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004169 267.0
WLSH2_k127_980945_2 - - - - 0.000000000000000000000000002969 114.0
WLSH2_k127_9812091_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 561.0
WLSH2_k127_9812091_1 cytochrome d1, heme region K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 551.0
WLSH2_k127_9812091_2 PFAM ATPase associated with various cellular activities K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 430.0
WLSH2_k127_9812091_3 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 328.0
WLSH2_k127_9812091_4 Cytochrome c oxidase subunit III K02164,K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 297.0
WLSH2_k127_9812091_5 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000006092 189.0
WLSH2_k127_9812091_6 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000002978 187.0
WLSH2_k127_9812091_7 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000001926 104.0
WLSH2_k127_9812091_8 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.000000000000000000001853 98.0
WLSH2_k127_9818635_0 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 577.0
WLSH2_k127_9818635_1 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 431.0
WLSH2_k127_9818635_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 342.0
WLSH2_k127_9818635_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 329.0
WLSH2_k127_9818635_4 META domain K03929 - - 0.00000000000000000000000000063 126.0
WLSH2_k127_9930110_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 566.0
WLSH2_k127_9930110_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 425.0
WLSH2_k127_9930110_2 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000000000000000000000000004408 212.0
WLSH2_k127_9930110_3 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000007382 197.0
WLSH2_k127_998203_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 6.784e-202 635.0
WLSH2_k127_998203_1 PFAM FAD dependent oxidoreductase K00116 - 1.1.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 501.0
WLSH2_k127_998203_2 pfam nudix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 358.0
WLSH2_k127_998203_3 PFAM MazG nucleotide pyrophosphohydrolase K04765 - 3.6.1.9 0.0000000000000000000000000000003826 124.0
WLSH2_k127_9991336_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1939.0
WLSH2_k127_9991336_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1017.0
WLSH2_k127_9991336_10 HEPN domain - - - 0.000000000002818 69.0
WLSH2_k127_9991336_2 Belongs to the peptidase S16 family K04770 - - 2.162e-292 918.0
WLSH2_k127_9991336_3 Alpha/beta-hydrolase family N-terminus - - - 6.559e-267 840.0
WLSH2_k127_9991336_4 - - - - 1.105e-207 654.0
WLSH2_k127_9991336_5 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 369.0
WLSH2_k127_9991336_6 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 347.0
WLSH2_k127_9991336_7 Host attachment protein - - - 0.00000000000000000000000000000000000000000000000000000003094 201.0
WLSH2_k127_9991336_8 Transposase - - - 0.000000000000000000000003245 108.0
WLSH2_k127_9991336_9 Oxygen tolerance - - - 0.000000000000000000001972 108.0