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Overview

ID MAG04210
Name WLSH2_bin.35
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus Sideroxyarcus
Species
Assembly information
Completeness (%) 72.08
Contamination (%) 2.66
GC content (%) 57.0
N50 (bp) 5,395
Genome size (bp) 2,117,989

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2324

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10001857_0 fad dependent oxidoreductase K07137 - - 2.28e-310 955.0
WLSH2_k127_10001857_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 497.0
WLSH2_k127_10001857_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 384.0
WLSH2_k127_10001857_3 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 329.0
WLSH2_k127_10001857_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 325.0
WLSH2_k127_10001857_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007529 279.0
WLSH2_k127_10001857_6 PFAM Dihaem cytochrome c - - - 0.000000000000000000000000001697 111.0
WLSH2_k127_10013871_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1164.0
WLSH2_k127_10013871_1 VirC1 protein K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 376.0
WLSH2_k127_10013871_2 Anthranilate synthase component I domain protein K01665,K13950 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000009102 207.0
WLSH2_k127_10013871_3 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000001463 128.0
WLSH2_k127_10013871_4 PFAM cytochrome c class I K08738 - - 0.000000000000000000000000002341 116.0
WLSH2_k127_10057628_0 Transcriptional regulatory protein ompR K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 323.0
WLSH2_k127_10057628_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000001068 222.0
WLSH2_k127_10088791_0 PFAM UMUC domain protein DNA-repair protein K03502 - - 3.835e-218 683.0
WLSH2_k127_10107779_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1047.0
WLSH2_k127_10107779_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 528.0
WLSH2_k127_10107779_2 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 362.0
WLSH2_k127_10107779_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005568 271.0
WLSH2_k127_10107779_5 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000002199 179.0
WLSH2_k127_10107779_6 FeoA K04758 - - 0.0000000000000000000000000000005077 123.0
WLSH2_k127_1020155_0 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 1.812e-232 728.0
WLSH2_k127_1020155_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 8.038e-230 711.0
WLSH2_k127_1020155_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000001092 74.0
WLSH2_k127_10202230_0 Pfam Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 333.0
WLSH2_k127_10202230_1 - - - - 0.0000000000000000000000000000000000000000000000001338 181.0
WLSH2_k127_10210677_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 428.0
WLSH2_k127_10210677_1 - - - - 0.0000000000000000000000003417 107.0
WLSH2_k127_10210677_2 Protein of unknown function (DUF433) - - - 0.00000000000000000000447 97.0
WLSH2_k127_10239918_0 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 349.0
WLSH2_k127_10239918_1 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002548 278.0
WLSH2_k127_10239918_2 PFAM glycine cleavage T protein (aminomethyl transferase) K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001682 245.0
WLSH2_k127_10239918_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002002 160.0
WLSH2_k127_10244448_0 TonB dependent receptor K02014 - - 0.0 1118.0
WLSH2_k127_10244448_1 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 5.286e-208 656.0
WLSH2_k127_10244448_2 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 301.0
WLSH2_k127_10244448_3 Bacterial regulatory protein, Fis family K15012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 287.0
WLSH2_k127_10244726_0 Abc transporter K02029,K10009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 330.0
WLSH2_k127_10244726_1 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000004638 250.0
WLSH2_k127_10244726_2 - - - - 0.0000000000000000000000000000000662 134.0
WLSH2_k127_10269407_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 509.0
WLSH2_k127_10269407_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 465.0
WLSH2_k127_10269407_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 426.0
WLSH2_k127_10269407_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000003181 221.0
WLSH2_k127_10269407_4 Hemerythrin HHE cation binding domain - - - 0.0000000005694 61.0
WLSH2_k127_10269407_5 PFAM Fibronectin, type III domain - - - 0.00000004018 67.0
WLSH2_k127_10269407_7 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.00004876 49.0
WLSH2_k127_10269407_8 - - - - 0.00005276 57.0
WLSH2_k127_1028182_0 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 325.0
WLSH2_k127_1028182_1 Lanthionine synthetase C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001958 269.0
WLSH2_k127_1028182_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000003179 192.0
WLSH2_k127_1028182_3 Lanthionine synthetase C family protein - - - 0.0000000000000000000000000000000000000000002907 175.0
WLSH2_k127_10288981_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 613.0
WLSH2_k127_10288981_1 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000002359 215.0
WLSH2_k127_10313242_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 2.191e-244 757.0
WLSH2_k127_10313242_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 488.0
WLSH2_k127_10313242_2 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 334.0
WLSH2_k127_10358691_0 type III restriction protein res subunit K01153 - 3.1.21.3 5.554e-308 950.0
WLSH2_k127_10358691_1 N-6 DNA methylase K03427 - 2.1.1.72 1.293e-297 920.0
WLSH2_k127_10358691_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 3.078e-195 616.0
WLSH2_k127_10358691_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 341.0
WLSH2_k127_10358691_4 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 331.0
WLSH2_k127_10358691_5 Transcriptional regulator, AbiEi antitoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003642 269.0
WLSH2_k127_10358691_6 Type I restriction modification DNA specificity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001011 261.0
WLSH2_k127_10358691_8 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.00002975 49.0
WLSH2_k127_10360276_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 5.884e-249 770.0
WLSH2_k127_10360276_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.063e-223 696.0
WLSH2_k127_10360276_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 352.0
WLSH2_k127_10360276_3 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000004629 165.0
WLSH2_k127_10360276_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000005013 81.0
WLSH2_k127_10375446_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 3.436e-238 739.0
WLSH2_k127_10375446_1 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 8.827e-206 646.0
WLSH2_k127_10375446_2 Nucleotidyl transferase K00978,K15669 - 2.7.7.33,2.7.7.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 521.0
WLSH2_k127_10375446_3 Winged helix-turn-helix DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000355 194.0
WLSH2_k127_10375446_4 TIGRFAM lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000001572 109.0
WLSH2_k127_10377584_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 450.0
WLSH2_k127_10377584_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000003545 131.0
WLSH2_k127_10377584_2 - - - - 0.0000000000000002957 80.0
WLSH2_k127_1038325_0 Diguanylate cyclase - - - 1.223e-255 799.0
WLSH2_k127_1038325_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 1.426e-218 684.0
WLSH2_k127_1038325_2 glycosyl - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 424.0
WLSH2_k127_1038325_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 348.0
WLSH2_k127_1038325_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000001286 195.0
WLSH2_k127_1038325_5 cytochrome - - - 0.000000000000000000000000000000000000004656 148.0
WLSH2_k127_1038325_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000575 134.0
WLSH2_k127_10392782_0 Domain of unknown function (DUF4398) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 272.0
WLSH2_k127_10392782_1 Domain of unknown function (DUF4398) - - - 0.00000000000000000000000000000000000000000000000000000000000001138 226.0
WLSH2_k127_10392782_2 alginic acid biosynthetic process K20276 - - 0.0000000000000000000000000000003819 136.0
WLSH2_k127_10392782_3 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000004275 110.0
WLSH2_k127_10392782_4 CsbD-like - - - 0.000000000000000000000003928 104.0
WLSH2_k127_10392782_5 Domain of unknown function (DUF4398) - - - 0.000000000000000000001618 98.0
WLSH2_k127_10392782_6 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000001539 92.0
WLSH2_k127_10401108_0 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 394.0
WLSH2_k127_10401108_1 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000008243 139.0
WLSH2_k127_10401370_0 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006578 475.0
WLSH2_k127_10401370_1 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 308.0
WLSH2_k127_10401370_2 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000003552 162.0
WLSH2_k127_10419300_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1244.0
WLSH2_k127_10419300_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 588.0
WLSH2_k127_10419300_11 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000003681 56.0
WLSH2_k127_10419300_12 TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - 0.00003493 50.0
WLSH2_k127_10419300_2 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 392.0
WLSH2_k127_10419300_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 306.0
WLSH2_k127_10419300_4 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000000000000000000000007319 192.0
WLSH2_k127_10419300_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000005609 171.0
WLSH2_k127_10419300_6 surface antigen - - - 0.000000000000000000000000000000001141 132.0
WLSH2_k127_10419300_7 nucleic-acid-binding protein contains PIN domain - - - 0.00000000000000000000000000002877 122.0
WLSH2_k127_10419300_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000001647 116.0
WLSH2_k127_10419300_9 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000008062 96.0
WLSH2_k127_10422438_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1204.0
WLSH2_k127_10422438_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.888e-240 749.0
WLSH2_k127_10422438_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 399.0
WLSH2_k127_10422438_3 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000000009619 112.0
WLSH2_k127_10434778_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000009839 203.0
WLSH2_k127_10434778_2 Protein of unknown function (DUF3301) - - - 0.00000000000000000000000000000005046 128.0
WLSH2_k127_10434778_4 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000003912 108.0
WLSH2_k127_10436976_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1200.0
WLSH2_k127_10436976_1 Cysteine-rich domain - - - 0.0 1007.0
WLSH2_k127_10436976_2 AAA domain K02224 - 6.3.5.11,6.3.5.9 2.171e-221 690.0
WLSH2_k127_10436976_3 Polysulphide reductase, NrfD K00185 - - 4.514e-218 680.0
WLSH2_k127_10436976_4 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 424.0
WLSH2_k127_10436976_5 - - - - 0.000000000000000000000000000000000000000000000000000000108 201.0
WLSH2_k127_10436976_6 Nitrate reductase gamma subunit - - - 0.00000000000000000000006344 98.0
WLSH2_k127_10447821_0 PFAM type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000259 218.0
WLSH2_k127_10447821_1 AAA domain - - - 0.00000000000000000000000000000000000000000002175 175.0
WLSH2_k127_1052066_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1786.0
WLSH2_k127_1052066_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.568e-257 795.0
WLSH2_k127_1052066_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005736 250.0
WLSH2_k127_1052066_11 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005765 244.0
WLSH2_k127_1052066_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000000002199 224.0
WLSH2_k127_1052066_13 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000000002184 214.0
WLSH2_k127_1052066_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000001954 146.0
WLSH2_k127_1052066_15 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000000000000000000000006622 130.0
WLSH2_k127_1052066_16 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000008905 78.0
WLSH2_k127_1052066_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 608.0
WLSH2_k127_1052066_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 394.0
WLSH2_k127_1052066_4 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 325.0
WLSH2_k127_1052066_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 310.0
WLSH2_k127_1052066_6 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 285.0
WLSH2_k127_1052066_7 type III restriction protein res subunit K01153 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002253 275.0
WLSH2_k127_1052066_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008801 257.0
WLSH2_k127_1052066_9 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000269 251.0
WLSH2_k127_10523746_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 531.0
WLSH2_k127_10523746_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 317.0
WLSH2_k127_10523746_2 - - - - 0.000000000000000004479 92.0
WLSH2_k127_10551594_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000002542 154.0
WLSH2_k127_10551594_1 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000004506 121.0
WLSH2_k127_10551594_2 diguanylate cyclase - - - 0.00000000000000000000000002462 119.0
WLSH2_k127_10570989_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 2.407e-221 696.0
WLSH2_k127_10570989_1 Protein of unknown function (DUF1415) K09941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 334.0
WLSH2_k127_10570989_2 Peptidoglycan-synthase activator LpoB K07337 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004192 251.0
WLSH2_k127_10570989_3 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000002656 151.0
WLSH2_k127_10570989_4 Nitroreductase K10679 GO:0000166,GO:0003674,GO:0003824,GO:0004155,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010181,GO:0016491,GO:0016645,GO:0016646,GO:0016651,GO:0016657,GO:0018545,GO:0018973,GO:0018974,GO:0019326,GO:0019439,GO:0032553,GO:0036094,GO:0042537,GO:0042802,GO:0043167,GO:0043168,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046256,GO:0046260,GO:0046263,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072490,GO:0072491,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 1.5.1.34 0.000000000000000000000000000000005782 131.0
WLSH2_k127_10580164_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1609.0
WLSH2_k127_10580164_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 1.367e-306 942.0
WLSH2_k127_10580164_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.724e-260 805.0
WLSH2_k127_10580164_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.743e-247 775.0
WLSH2_k127_10580164_4 DNA-damage-inducible protein d K14623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 438.0
WLSH2_k127_10580164_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007999 394.0
WLSH2_k127_10580164_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000008129 224.0
WLSH2_k127_10580164_7 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000001857 136.0
WLSH2_k127_10580164_8 DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000000001813 111.0
WLSH2_k127_10580164_9 domain, Protein - - - 0.0000000001308 75.0
WLSH2_k127_10628350_0 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 555.0
WLSH2_k127_10628350_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 509.0
WLSH2_k127_10628350_2 Belongs to the 'phage' integrase family - - - 0.00000000006247 66.0
WLSH2_k127_10683881_0 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 366.0
WLSH2_k127_10683881_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 370.0
WLSH2_k127_10683881_2 Protein of unknown function, DUF481 K07283 - - 0.000000000000006045 76.0
WLSH2_k127_10743684_0 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 6.738e-226 707.0
WLSH2_k127_10743684_1 SMART ATPase, AAA type, core K06158 - - 0.000001792 50.0
WLSH2_k127_10826234_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.274e-205 642.0
WLSH2_k127_10826234_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 294.0
WLSH2_k127_10826234_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000001184 139.0
WLSH2_k127_10843376_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.663e-314 972.0
WLSH2_k127_10843376_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 473.0
WLSH2_k127_10843376_2 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 437.0
WLSH2_k127_10843376_3 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 282.0
WLSH2_k127_10843376_4 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000425 202.0
WLSH2_k127_10855066_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 509.0
WLSH2_k127_10855066_1 Rhodanese Homology Domain K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 481.0
WLSH2_k127_10866620_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 501.0
WLSH2_k127_10866620_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 386.0
WLSH2_k127_10866620_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006311 273.0
WLSH2_k127_10898438_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001132 286.0
WLSH2_k127_10898438_1 formate dehydrogenase K00126 - 1.17.1.9 0.0000000000000005467 83.0
WLSH2_k127_10898438_2 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.0000000001619 61.0
WLSH2_k127_10906509_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 7.043e-266 822.0
WLSH2_k127_10906509_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.417e-259 800.0
WLSH2_k127_10906509_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 322.0
WLSH2_k127_10906509_3 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 313.0
WLSH2_k127_10906509_4 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 309.0
WLSH2_k127_10906509_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008076 272.0
WLSH2_k127_10928589_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 628.0
WLSH2_k127_10928589_1 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000001559 232.0
WLSH2_k127_10928589_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004517 231.0
WLSH2_k127_10928589_3 Domain of unknown function (DUF1924) - - - 0.000000002311 61.0
WLSH2_k127_10988256_0 SMART HTH transcriptional regulator, Crp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 332.0
WLSH2_k127_10988256_1 SMART HTH transcriptional regulator, Crp - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 302.0
WLSH2_k127_10988256_2 Sigma-70 factor, region 1.2 K03087 - - 0.0000000000002875 71.0
WLSH2_k127_10988256_3 Histidine kinase - - - 0.000000001353 59.0
WLSH2_k127_11005590_0 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 424.0
WLSH2_k127_11005590_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 409.0
WLSH2_k127_11005590_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000002812 64.0
WLSH2_k127_11010979_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1103.0
WLSH2_k127_11010979_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 402.0
WLSH2_k127_11010979_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
WLSH2_k127_11010979_3 - - - - 0.000000000002803 71.0
WLSH2_k127_11043528_0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 352.0
WLSH2_k127_11043528_1 phenylacetate-CoA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000009909 220.0
WLSH2_k127_11043528_2 VanZ like family - - - 0.0000000000000000000000000000000000000000002592 160.0
WLSH2_k127_11087239_0 PFAM type II secretion system protein E K02670 - - 8.929e-219 682.0
WLSH2_k127_11098358_0 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 2.636e-212 661.0
WLSH2_k127_11098358_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 297.0
WLSH2_k127_11098358_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000001026 85.0
WLSH2_k127_11184426_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1630.0
WLSH2_k127_11184426_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1005.0
WLSH2_k127_11184426_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 2.246e-224 700.0
WLSH2_k127_11184426_3 Protein of unknown function (DUF815) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 546.0
WLSH2_k127_11184426_4 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 408.0
WLSH2_k127_11184426_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002032 247.0
WLSH2_k127_11184426_6 Protein of unknown function (DUF721) - - - 0.000000000000000000007392 95.0
WLSH2_k127_11191288_0 glutamate synthase alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2891.0
WLSH2_k127_11191288_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000001328 203.0
WLSH2_k127_11197960_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1941.0
WLSH2_k127_11197960_1 PFAM N-6 DNA methylase K03427 - 2.1.1.72 0.0 1290.0
WLSH2_k127_11197960_2 restriction modification system DNA specificity K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 358.0
WLSH2_k127_11197960_3 Threonyl and Alanyl tRNA synthetase second additional domain K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003363 265.0
WLSH2_k127_11197960_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000000000000000000000000000000000001639 164.0
WLSH2_k127_11197960_5 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000000000000000001717 130.0
WLSH2_k127_11197960_6 SpoVT / AbrB like domain K07172 - - 0.000000000000000000000005603 103.0
WLSH2_k127_11197960_7 Permease MlaE K02066 - - 0.0000000000000000000002504 96.0
WLSH2_k127_11222789_0 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 576.0
WLSH2_k127_11222789_1 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 538.0
WLSH2_k127_11222789_2 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 524.0
WLSH2_k127_11222789_3 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 338.0
WLSH2_k127_11229228_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 555.0
WLSH2_k127_11229228_1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 466.0
WLSH2_k127_11229228_2 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 318.0
WLSH2_k127_11229228_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000006378 141.0
WLSH2_k127_11236993_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.051e-308 952.0
WLSH2_k127_11236993_1 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 374.0
WLSH2_k127_11236993_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000002564 130.0
WLSH2_k127_11236993_3 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000007037 50.0
WLSH2_k127_11249423_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1011.0
WLSH2_k127_11249423_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 308.0
WLSH2_k127_11249423_2 PFAM Type II secretion system F domain K02455,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009125 275.0
WLSH2_k127_11249423_3 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000000000000004855 87.0
WLSH2_k127_11269635_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 413.0
WLSH2_k127_11269635_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 394.0
WLSH2_k127_11269635_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 317.0
WLSH2_k127_11275131_0 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 610.0
WLSH2_k127_11275131_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 434.0
WLSH2_k127_11275131_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 350.0
WLSH2_k127_11275131_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001052 269.0
WLSH2_k127_11275131_4 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000001066 216.0
WLSH2_k127_11275131_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000005024 164.0
WLSH2_k127_11275131_6 - - - - 0.0000000000000000000015 104.0
WLSH2_k127_11281729_0 PFAM Carbamoyl-phosphate synthase L chain K01959 - 6.4.1.1 6.437e-279 861.0
WLSH2_k127_11281729_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 576.0
WLSH2_k127_11281729_2 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 348.0
WLSH2_k127_11281729_3 PIN domain - - - 0.0000000000000000000000000000000000000000000808 162.0
WLSH2_k127_11281729_4 SpoVT / AbrB like domain - - - 0.000000000000000000001743 96.0
WLSH2_k127_11297659_0 Sodium:solute symporter family K14393 - - 0.0 1195.0
WLSH2_k127_11297659_1 SMART CBS domain containing protein K07182 - - 0.0 1071.0
WLSH2_k127_11297659_10 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 459.0
WLSH2_k127_11297659_11 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 457.0
WLSH2_k127_11297659_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 433.0
WLSH2_k127_11297659_13 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 419.0
WLSH2_k127_11297659_14 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 390.0
WLSH2_k127_11297659_15 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 385.0
WLSH2_k127_11297659_16 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 373.0
WLSH2_k127_11297659_17 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 361.0
WLSH2_k127_11297659_18 mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 342.0
WLSH2_k127_11297659_19 PfkB domain protein K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 343.0
WLSH2_k127_11297659_2 PFAM Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0 1070.0
WLSH2_k127_11297659_20 PFAM cytochrome c biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 331.0
WLSH2_k127_11297659_21 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 323.0
WLSH2_k127_11297659_22 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 316.0
WLSH2_k127_11297659_23 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
WLSH2_k127_11297659_24 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 297.0
WLSH2_k127_11297659_25 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000557 284.0
WLSH2_k127_11297659_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002658 269.0
WLSH2_k127_11297659_27 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001568 252.0
WLSH2_k127_11297659_28 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000003989 230.0
WLSH2_k127_11297659_29 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000697 213.0
WLSH2_k127_11297659_3 Sucrose synthase K00696 - 2.4.1.14 0.0 1027.0
WLSH2_k127_11297659_30 MarR family - - - 0.000000000000000000000000000000000000000000000000000000000007804 210.0
WLSH2_k127_11297659_31 Redoxin - - - 0.000000000000000000000000000000000000000000000003527 179.0
WLSH2_k127_11297659_32 DsrE/DsrF-like family K06039 - - 0.00000000000000000000000000000000000000000000003622 173.0
WLSH2_k127_11297659_33 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000000000000001778 154.0
WLSH2_k127_11297659_34 - - - - 0.00000000000000000000000000000000000000001895 155.0
WLSH2_k127_11297659_35 Pfam Thioredoxin - - - 0.00000000000000000000000000000000000008352 145.0
WLSH2_k127_11297659_36 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000000002234 143.0
WLSH2_k127_11297659_37 OmpA family K03640 - - 0.00000000000000000000000000008755 123.0
WLSH2_k127_11297659_38 TRANSCRIPTIONal - - - 0.00000000000000000000000000176 116.0
WLSH2_k127_11297659_39 - - - - 0.00000000000000000000000491 104.0
WLSH2_k127_11297659_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1022.0
WLSH2_k127_11297659_40 cystathionine gamma-synthase activity - - - 0.00000000000000000005355 104.0
WLSH2_k127_11297659_41 Helix-turn-helix XRE-family like proteins - - - 0.000000000000001141 82.0
WLSH2_k127_11297659_42 Diguanylate cyclase - - - 0.00000000000001532 83.0
WLSH2_k127_11297659_44 Major facilitator Superfamily - - - 0.00001355 48.0
WLSH2_k127_11297659_5 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 4.076e-239 745.0
WLSH2_k127_11297659_6 Major Facilitator - - - 2.969e-219 691.0
WLSH2_k127_11297659_7 Chloride channel - - - 9.398e-213 667.0
WLSH2_k127_11297659_8 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 571.0
WLSH2_k127_11297659_9 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 576.0
WLSH2_k127_11311535_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 485.0
WLSH2_k127_11311535_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000001563 237.0
WLSH2_k127_11311535_2 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000004739 188.0
WLSH2_k127_11324253_0 PFAM type II secretion system protein E K02670 - - 4.754e-220 685.0
WLSH2_k127_11324253_1 PFAM type II secretion system protein E K02669,K12203 - - 1.189e-208 650.0
WLSH2_k127_11324253_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 396.0
WLSH2_k127_11324253_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 364.0
WLSH2_k127_11324253_4 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004659 276.0
WLSH2_k127_11324253_5 PFAM cytochrome c biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001343 263.0
WLSH2_k127_11324253_7 DUF167 K09131 - - 0.0000000000000000000000000000000000000000000004889 168.0
WLSH2_k127_11332497_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.837e-261 805.0
WLSH2_k127_11332497_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 1.38e-226 710.0
WLSH2_k127_11332497_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 597.0
WLSH2_k127_11332497_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 361.0
WLSH2_k127_11332497_4 Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 313.0
WLSH2_k127_11332497_5 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000008543 175.0
WLSH2_k127_11332497_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000002601 139.0
WLSH2_k127_11332497_7 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000002203 136.0
WLSH2_k127_11332497_8 Protein of unknown function (DUF520) K09767 - - 0.00000000000479 67.0
WLSH2_k127_11369626_0 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 497.0
WLSH2_k127_11369626_1 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 389.0
WLSH2_k127_11373014_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.232e-236 737.0
WLSH2_k127_11373014_1 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004018 242.0
WLSH2_k127_11373014_2 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
WLSH2_k127_11373014_3 STAS domain K07122 - - 0.000000005418 61.0
WLSH2_k127_11394795_0 Tetratricopeptide repeats - - - 4.942e-224 709.0
WLSH2_k127_11394795_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 2.478e-221 690.0
WLSH2_k127_11394795_10 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000127 283.0
WLSH2_k127_11394795_11 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000002454 228.0
WLSH2_k127_11394795_12 - - - - 0.000000000000000000000002226 109.0
WLSH2_k127_11394795_13 - - - - 0.0000003463 54.0
WLSH2_k127_11394795_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 599.0
WLSH2_k127_11394795_3 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 593.0
WLSH2_k127_11394795_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 495.0
WLSH2_k127_11394795_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 417.0
WLSH2_k127_11394795_6 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 361.0
WLSH2_k127_11394795_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 355.0
WLSH2_k127_11394795_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 337.0
WLSH2_k127_11394795_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 319.0
WLSH2_k127_11407367_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1108.0
WLSH2_k127_11407367_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 503.0
WLSH2_k127_11407367_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 425.0
WLSH2_k127_11407367_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
WLSH2_k127_11407367_4 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007728 276.0
WLSH2_k127_11407367_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003697 271.0
WLSH2_k127_11407367_6 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.0000000000000000000000000000000000000000000000000000000000000005149 225.0
WLSH2_k127_11436837_0 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 454.0
WLSH2_k127_11436837_1 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 342.0
WLSH2_k127_11436837_2 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000923 250.0
WLSH2_k127_11436837_3 - - - - 0.0000000000000000000000000002157 119.0
WLSH2_k127_11436837_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000003763 94.0
WLSH2_k127_11441925_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 2.621e-215 670.0
WLSH2_k127_11441925_1 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 529.0
WLSH2_k127_11441925_2 - - - - 0.000000000000000000000000000000000000000000000000000003589 196.0
WLSH2_k127_11499744_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.875e-259 803.0
WLSH2_k127_11499744_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 379.0
WLSH2_k127_123616_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 398.0
WLSH2_k127_123616_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 351.0
WLSH2_k127_123616_2 COG1943 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000008231 152.0
WLSH2_k127_123616_3 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K03413 - - 0.0000000000000000000000001047 107.0
WLSH2_k127_123616_4 Histidine Phosphotransfer domain - - - 0.000000000000005579 88.0
WLSH2_k127_1261705_0 Dyp-type peroxidase family K07223 - - 0.0 1279.0
WLSH2_k127_1261705_1 phospholipase C K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 612.0
WLSH2_k127_1261705_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 309.0
WLSH2_k127_1261705_11 PFAM CHASE2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007786 261.0
WLSH2_k127_1261705_12 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003547 226.0
WLSH2_k127_1261705_14 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000001623 153.0
WLSH2_k127_1261705_15 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000004442 128.0
WLSH2_k127_1261705_16 transmembrane transport - - - 0.00000000000000000000000002047 118.0
WLSH2_k127_1261705_18 - - - - 0.000000000000001603 87.0
WLSH2_k127_1261705_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000368 49.0
WLSH2_k127_1261705_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 580.0
WLSH2_k127_1261705_3 hydroxypyruvate reductase K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 574.0
WLSH2_k127_1261705_4 glycosyl transferase family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 545.0
WLSH2_k127_1261705_5 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 516.0
WLSH2_k127_1261705_6 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 427.0
WLSH2_k127_1261705_7 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 415.0
WLSH2_k127_1261705_8 CrtC N-terminal lipocalin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 379.0
WLSH2_k127_1270060_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 522.0
WLSH2_k127_1270060_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 464.0
WLSH2_k127_1270060_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 392.0
WLSH2_k127_1270060_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 392.0
WLSH2_k127_1270060_4 Glycosyl transferase, family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 381.0
WLSH2_k127_1270060_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000000004738 155.0
WLSH2_k127_1270060_6 PFAM polysaccharide biosynthesis protein CapD - - - 0.00000000000000000000000000000000000002492 144.0
WLSH2_k127_1270060_7 O-antigen ligase like membrane protein K02847 - - 0.000000000000000000000000001999 127.0
WLSH2_k127_1272245_0 LysR substrate binding domain K13634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 586.0
WLSH2_k127_1272245_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000002516 162.0
WLSH2_k127_1272245_2 Thioredoxin K05838 - - 0.00000000000000008315 80.0
WLSH2_k127_1274200_0 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.0 1046.0
WLSH2_k127_1274200_1 LysR substrate binding domain K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 486.0
WLSH2_k127_1276690_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 297.0
WLSH2_k127_1276690_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000141 148.0
WLSH2_k127_1310888_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 0.0 1105.0
WLSH2_k127_1310888_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002563 258.0
WLSH2_k127_1310888_2 GIY-YIG type nucleases (URI domain) K07461 - - 0.00000000000000000000000000000000000001182 146.0
WLSH2_k127_1319833_0 Radical SAM K04069 - 1.97.1.4 4.514e-218 680.0
WLSH2_k127_1319833_1 Evidence 4 Homologs of previously reported genes of - - - 8.364e-196 617.0
WLSH2_k127_1319833_10 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000000000813 172.0
WLSH2_k127_1319833_11 response to abiotic stimulus K06867 - - 0.000000000000000000000000000000000000008679 153.0
WLSH2_k127_1319833_12 - - - - 0.0000000000000000000000000000007587 125.0
WLSH2_k127_1319833_2 metal-dependent phosphohydrolase HD sub domain K07814,K13815 - - 4.887e-194 616.0
WLSH2_k127_1319833_3 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 457.0
WLSH2_k127_1319833_4 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 419.0
WLSH2_k127_1319833_5 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 398.0
WLSH2_k127_1319833_6 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K07216 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 323.0
WLSH2_k127_1319833_7 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001127 243.0
WLSH2_k127_1319833_8 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000009074 234.0
WLSH2_k127_1319833_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000001212 199.0
WLSH2_k127_1334326_0 heat shock protein binding - - - 1.249e-265 828.0
WLSH2_k127_1334326_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 6.206e-222 695.0
WLSH2_k127_1334326_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009036 232.0
WLSH2_k127_1334326_11 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000002486 69.0
WLSH2_k127_1334326_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 8.441e-216 675.0
WLSH2_k127_1334326_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 1.226e-208 673.0
WLSH2_k127_1334326_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 578.0
WLSH2_k127_1334326_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 422.0
WLSH2_k127_1334326_6 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 383.0
WLSH2_k127_1334326_7 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 336.0
WLSH2_k127_1334326_8 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 310.0
WLSH2_k127_1334326_9 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002032 254.0
WLSH2_k127_1334398_0 cyclic-guanylate-specific phosphodiesterase activity - - - 8.076e-224 718.0
WLSH2_k127_1334398_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 309.0
WLSH2_k127_1334398_2 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000000000000000000000000000000009812 173.0
WLSH2_k127_1334398_3 Histidine kinase - - - 0.000000000000000000000000000000000000215 159.0
WLSH2_k127_1336402_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 567.0
WLSH2_k127_1336402_1 Pfam ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001548 229.0
WLSH2_k127_1336402_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000001007 205.0
WLSH2_k127_1337090_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1339.0
WLSH2_k127_1337090_1 histidine kinase HAMP region domain protein - - - 1.397e-310 965.0
WLSH2_k127_1337090_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 1.957e-235 731.0
WLSH2_k127_1337090_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 4.824e-198 619.0
WLSH2_k127_1337090_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 577.0
WLSH2_k127_1337090_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 441.0
WLSH2_k127_1337090_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 435.0
WLSH2_k127_1337090_7 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 339.0
WLSH2_k127_1337090_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000001681 263.0
WLSH2_k127_1337090_9 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000001966 175.0
WLSH2_k127_1342520_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 511.0
WLSH2_k127_1342520_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 323.0
WLSH2_k127_1342520_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 295.0
WLSH2_k127_1342520_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000001119 199.0
WLSH2_k127_1342520_4 chlorophyll binding - - - 0.000000000000000000000000000000001345 134.0
WLSH2_k127_1342520_5 Trm112p-like protein K09791 - - 0.000000000000000000000004483 108.0
WLSH2_k127_1372307_0 aminoacyl-histidine dipeptidase K01270 - - 7.98e-226 708.0
WLSH2_k127_1372307_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 402.0
WLSH2_k127_1372307_2 -acetyltransferase K17840 - 2.3.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 386.0
WLSH2_k127_1372307_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000007587 125.0
WLSH2_k127_1382735_0 Homoserine dehydrogenase K00003 - 1.1.1.3 2.08e-262 811.0
WLSH2_k127_1382735_1 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 6.443e-257 795.0
WLSH2_k127_1382735_2 Threonine synthase N terminus K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 366.0
WLSH2_k127_1382735_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000293 157.0
WLSH2_k127_1403883_0 S-adenosyl-L-methionine-dependent methyltransferase K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 580.0
WLSH2_k127_1403883_1 - - - - 0.00000000000000000000000000000000000000000000000005625 186.0
WLSH2_k127_1403883_3 - - - - 0.000000000000000003523 87.0
WLSH2_k127_14094_0 PFAM TonB-dependent receptor plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 470.0
WLSH2_k127_14094_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 368.0
WLSH2_k127_14094_2 transport system periplasmic component K01989 - - 0.00000000000000000000000000000000000000000000007619 180.0
WLSH2_k127_14094_3 Radical SAM - - - 0.0000000000000000000000000000000002857 133.0
WLSH2_k127_1413083_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 9.938e-197 621.0
WLSH2_k127_1413083_1 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.000000000000000000000000000000000000721 141.0
WLSH2_k127_1494392_0 Type III restriction - - - 0.0 1291.0
WLSH2_k127_1494392_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1031.0
WLSH2_k127_1494392_2 SMART adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 541.0
WLSH2_k127_1494392_3 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 507.0
WLSH2_k127_1494392_4 HipA domain protein K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 430.0
WLSH2_k127_1494392_5 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 354.0
WLSH2_k127_1494392_6 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000002667 157.0
WLSH2_k127_1494392_7 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000001054 127.0
WLSH2_k127_1494392_8 sequence-specific DNA binding K15773 - - 0.0000000002147 65.0
WLSH2_k127_1518215_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1116.0
WLSH2_k127_1518215_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.869e-274 844.0
WLSH2_k127_1518215_2 Histidine kinase K07673 - 2.7.13.3 6.625e-235 730.0
WLSH2_k127_1518215_3 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.106e-210 661.0
WLSH2_k127_1518215_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 313.0
WLSH2_k127_1518215_5 NlpC/P60 family K19303 - - 0.0000000000000000000000000000000000000000000000000000000000001255 218.0
WLSH2_k127_1518215_6 Bacterial regulatory proteins, luxR family K07684 - - 0.000000000000000000000000000000000000000000000000000000000004328 217.0
WLSH2_k127_1518215_7 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000003791 117.0
WLSH2_k127_1526115_0 Major Facilitator Superfamily - - - 1.969e-224 702.0
WLSH2_k127_1526115_1 Belongs to the DegT DnrJ EryC1 family - - - 3.136e-224 697.0
WLSH2_k127_1526115_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
WLSH2_k127_1526115_3 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000002037 210.0
WLSH2_k127_1526115_4 Plasmid stabilization system K19092 - - 0.000000000000000000000000000000000000000004357 156.0
WLSH2_k127_1526115_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000000000003672 139.0
WLSH2_k127_1526115_6 DsrC like protein K11179 - - 0.000000000000000000002084 93.0
WLSH2_k127_1526115_7 - - - - 0.000000002977 68.0
WLSH2_k127_16361_0 AcrB/AcrD/AcrF family - - - 7.393e-273 846.0
WLSH2_k127_16361_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 327.0
WLSH2_k127_16361_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000006909 126.0
WLSH2_k127_165164_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.586e-303 946.0
WLSH2_k127_165164_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 583.0
WLSH2_k127_165164_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 366.0
WLSH2_k127_165164_3 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 361.0
WLSH2_k127_165164_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000019 248.0
WLSH2_k127_1658944_0 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 310.0
WLSH2_k127_1658944_2 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000001433 192.0
WLSH2_k127_1658944_3 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.00000000000000000000000000000000000000001404 154.0
WLSH2_k127_1658944_5 Plasmid stabilization system K19092 - - 0.0000000000000000000000006916 108.0
WLSH2_k127_1658944_7 Putative addiction module component - - - 0.00000000000104 70.0
WLSH2_k127_1664319_0 Involved in the TonB-independent uptake of proteins K03641 - - 6.593e-199 626.0
WLSH2_k127_1664319_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 401.0
WLSH2_k127_1664319_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000004647 103.0
WLSH2_k127_1664319_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000001084 79.0
WLSH2_k127_1664319_2 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 391.0
WLSH2_k127_1664319_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 382.0
WLSH2_k127_1664319_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 295.0
WLSH2_k127_1664319_5 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000003259 229.0
WLSH2_k127_1664319_6 TIGRFAM TonB family protein K03646 - - 0.000000000000000000000000000000000000000000000000000000000001758 218.0
WLSH2_k127_1664319_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000131 208.0
WLSH2_k127_1664319_8 OmpA family K03640 - - 0.000000000000000000000000000000000000004409 154.0
WLSH2_k127_1664319_9 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000000000004148 136.0
WLSH2_k127_1667238_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 4.725e-256 793.0
WLSH2_k127_1667238_1 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 6.267e-256 794.0
WLSH2_k127_1667238_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001733 258.0
WLSH2_k127_1667238_3 Helix-turn-helix XRE-family like proteins - - - 0.0000001886 55.0
WLSH2_k127_1667238_4 - - - - 0.0001765 46.0
WLSH2_k127_1673796_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 5.031e-199 620.0
WLSH2_k127_1673796_1 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 521.0
WLSH2_k127_1673796_2 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001283 283.0
WLSH2_k127_1673796_3 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000000000000000000000000000000000008434 201.0
WLSH2_k127_1673796_4 DoxX-like family - - - 0.000000000000003141 78.0
WLSH2_k127_1673796_5 epimerase dehydratase - - - 0.00000000000003191 74.0
WLSH2_k127_1673796_6 DoxX-like family - - - 0.000000002555 67.0
WLSH2_k127_1678595_0 SMART RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000000000000000000000000000001003 200.0
WLSH2_k127_1678595_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000156 133.0
WLSH2_k127_1678595_2 Protein of unknown function (DUF3313) - - - 0.0000000000000000000001528 106.0
WLSH2_k127_1678595_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000007597 86.0
WLSH2_k127_1678595_4 Chitinase class I K03791 - - 0.000000001942 69.0
WLSH2_k127_1688643_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1096.0
WLSH2_k127_1688643_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000002819 181.0
WLSH2_k127_1688643_2 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000001341 136.0
WLSH2_k127_1694700_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 1.981e-275 850.0
WLSH2_k127_1694700_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 337.0
WLSH2_k127_1694700_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 299.0
WLSH2_k127_1694700_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001036 248.0
WLSH2_k127_1697352_0 cofactor biosynthesis protein NifB K02585 - - 7.033e-220 684.0
WLSH2_k127_1697352_1 NifQ K15790 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 289.0
WLSH2_k127_1697352_2 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002461 234.0
WLSH2_k127_1697352_3 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000000000000000000000000000003043 217.0
WLSH2_k127_1697352_4 4Fe-4S ferredoxin iron-sulfur binding domain - - - 0.00000000000000000000000000000000000000000004765 161.0
WLSH2_k127_1697352_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000002857 133.0
WLSH2_k127_1701576_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 519.0
WLSH2_k127_1701576_1 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000003523 168.0
WLSH2_k127_1701576_2 Plasmid stabilization system K19092 - - 0.00000000000000000000000000000241 126.0
WLSH2_k127_1701576_3 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000000000000000000000002974 104.0
WLSH2_k127_1711820_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1398.0
WLSH2_k127_1711820_1 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 503.0
WLSH2_k127_1711820_2 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000009825 181.0
WLSH2_k127_1711820_3 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000009802 164.0
WLSH2_k127_1719504_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006,K01007 - 2.7.9.1,2.7.9.2 1.428e-273 844.0
WLSH2_k127_1719504_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 507.0
WLSH2_k127_1719504_2 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000001131 171.0
WLSH2_k127_1740883_0 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 430.0
WLSH2_k127_1740883_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 391.0
WLSH2_k127_1740883_2 Hydrogenase expression formation protein K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004484 252.0
WLSH2_k127_1740883_3 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004009 244.0
WLSH2_k127_1740883_4 Hydrogenase expression formation protein K03605 - - 0.00000000000000000000000000000000000005834 143.0
WLSH2_k127_1740883_5 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000000000005815 137.0
WLSH2_k127_1741987_0 Domain of unknown function (DUF3400) - - - 0.0 2194.0
WLSH2_k127_1741987_1 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 590.0
WLSH2_k127_1741987_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 558.0
WLSH2_k127_1741987_3 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 426.0
WLSH2_k127_1741987_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000002042 128.0
WLSH2_k127_1745247_0 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 572.0
WLSH2_k127_1745247_1 CRP FNR family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004243 278.0
WLSH2_k127_1745247_2 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000002033 189.0
WLSH2_k127_1745247_3 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000001349 115.0
WLSH2_k127_1745247_4 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein K07485 - - 0.0001746 44.0
WLSH2_k127_1759765_0 diguanylate cyclase - - - 1.032e-206 664.0
WLSH2_k127_1759765_1 Histidine kinase K20975 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 320.0
WLSH2_k127_1759765_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000182 246.0
WLSH2_k127_1759765_3 - - - - 0.00001114 53.0
WLSH2_k127_1795824_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 6.952e-206 661.0
WLSH2_k127_1795824_1 Monomeric isocitrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 502.0
WLSH2_k127_1795824_2 Cytochrome c K08738 - - 0.0003061 43.0
WLSH2_k127_1843880_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K06148,K18889 - - 3.422e-232 732.0
WLSH2_k127_1843880_1 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 453.0
WLSH2_k127_1843880_2 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 286.0
WLSH2_k127_1861029_0 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 5.644e-243 753.0
WLSH2_k127_1861029_2 Recombinase zinc beta ribbon domain - - - 0.0003898 47.0
WLSH2_k127_18688_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 532.0
WLSH2_k127_18688_1 Transcriptional regulator, LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 519.0
WLSH2_k127_18688_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 321.0
WLSH2_k127_18688_3 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002606 280.0
WLSH2_k127_18688_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002669 258.0
WLSH2_k127_18688_5 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000007839 147.0
WLSH2_k127_18688_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000001763 109.0
WLSH2_k127_1887735_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1144.0
WLSH2_k127_1887735_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 604.0
WLSH2_k127_1887735_2 FIST_C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 579.0
WLSH2_k127_1887735_3 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 445.0
WLSH2_k127_1887735_4 - - - - 0.000000000000000000000000000000000000000000000000000002339 195.0
WLSH2_k127_1897359_0 - - - - 0.000000000000000000000000000000000000000000003188 169.0
WLSH2_k127_1897359_1 - - - - 0.000000000002409 68.0
WLSH2_k127_1901707_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 537.0
WLSH2_k127_1901707_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001195 235.0
WLSH2_k127_1901707_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000001417 97.0
WLSH2_k127_1944978_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.511e-202 631.0
WLSH2_k127_1944978_1 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 287.0
WLSH2_k127_1944978_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007149 264.0
WLSH2_k127_195726_0 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 485.0
WLSH2_k127_195726_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 310.0
WLSH2_k127_2033980_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 388.0
WLSH2_k127_205959_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 578.0
WLSH2_k127_205959_1 AAA domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 381.0
WLSH2_k127_205959_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 339.0
WLSH2_k127_205959_3 cyclic nucleotide binding K01420,K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005971 240.0
WLSH2_k127_205959_4 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000000000000341 229.0
WLSH2_k127_205959_5 - - - - 0.0000000000000000000001235 98.0
WLSH2_k127_2141185_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 580.0
WLSH2_k127_2141185_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 380.0
WLSH2_k127_2141185_2 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 306.0
WLSH2_k127_2141185_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005078 267.0
WLSH2_k127_2141185_4 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003217 258.0
WLSH2_k127_2141185_5 - - - - 0.00000000000000000000823 92.0
WLSH2_k127_2144199_0 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K07006,K21832 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 610.0
WLSH2_k127_2144199_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 325.0
WLSH2_k127_2144199_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 322.0
WLSH2_k127_2144199_3 WLM domain K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003054 268.0
WLSH2_k127_2151231_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 475.0
WLSH2_k127_2151231_1 Beta-lactamase - - - 0.0000000000000000009686 93.0
WLSH2_k127_2165414_0 MacB-like periplasmic core domain K02004 - - 1.455e-216 676.0
WLSH2_k127_2165414_1 filamentation induced by cAMP protein Fic - - - 7.871e-211 664.0
WLSH2_k127_2165414_10 PFAM Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004765 243.0
WLSH2_k127_2165414_11 related to short-chain alcohol - - - 0.0000000000000000000000000000000000000000000000000000001024 203.0
WLSH2_k127_2165414_12 - - - - 0.0000000000000000000000000000000000000000000000000003837 193.0
WLSH2_k127_2165414_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000006085 185.0
WLSH2_k127_2165414_14 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000004499 145.0
WLSH2_k127_2165414_16 NAD dependent epimerase dehydratase family - - - 0.00000003856 59.0
WLSH2_k127_2165414_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 599.0
WLSH2_k127_2165414_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 449.0
WLSH2_k127_2165414_4 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 427.0
WLSH2_k127_2165414_5 nucleotide-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 424.0
WLSH2_k127_2165414_6 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 378.0
WLSH2_k127_2165414_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 353.0
WLSH2_k127_2165414_8 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 342.0
WLSH2_k127_2165414_9 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002244 271.0
WLSH2_k127_2170247_0 B3/4 domain K01890 - 6.1.1.20 3.952e-292 902.0
WLSH2_k127_2170247_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 4.215e-212 659.0
WLSH2_k127_2172093_0 SMART band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 387.0
WLSH2_k127_2172093_1 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 324.0
WLSH2_k127_2172093_2 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000009648 94.0
WLSH2_k127_2172093_3 Ammonium Transporter Family K03320,K06580 - - 0.0000000003559 61.0
WLSH2_k127_2198320_0 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1020.0
WLSH2_k127_2198320_1 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 302.0
WLSH2_k127_2198320_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000004361 113.0
WLSH2_k127_2199075_0 transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 512.0
WLSH2_k127_2199075_1 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 443.0
WLSH2_k127_2199075_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000002528 78.0
WLSH2_k127_2199075_3 Winged helix DNA-binding domain - - - 0.000000000000001454 79.0
WLSH2_k127_2205257_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 422.0
WLSH2_k127_2205257_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 278.0
WLSH2_k127_2205257_2 Transcriptional regulatory protein, C terminal K07663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003052 276.0
WLSH2_k127_2205257_3 His Kinase A (phosphoacceptor) domain K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000002512 232.0
WLSH2_k127_2215528_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 422.0
WLSH2_k127_2215528_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 400.0
WLSH2_k127_2215528_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001217 258.0
WLSH2_k127_2215528_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 248.0
WLSH2_k127_2215528_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000125 186.0
WLSH2_k127_2244244_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 522.0
WLSH2_k127_2244244_1 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.000000000000000000000000000000000000000000000000000000009827 199.0
WLSH2_k127_2244244_2 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000000000000008391 153.0
WLSH2_k127_2244244_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000634 122.0
WLSH2_k127_2265753_0 Part of a membrane complex involved in electron transport K03614 - - 5.773e-203 634.0
WLSH2_k127_2265753_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03314 GO:0003674,GO:0005215,GO:0005451,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006873,GO:0006885,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010226,GO:0015075,GO:0015077,GO:0015078,GO:0015081,GO:0015291,GO:0015297,GO:0015298,GO:0015299,GO:0015318,GO:0015385,GO:0015491,GO:0015672,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0035725,GO:0042221,GO:0042592,GO:0044464,GO:0045851,GO:0046873,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 536.0
WLSH2_k127_2265753_2 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 329.0
WLSH2_k127_2265753_3 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 327.0
WLSH2_k127_2265753_4 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000001018 223.0
WLSH2_k127_2265753_5 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000000002144 154.0
WLSH2_k127_2265753_6 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000005035 108.0
WLSH2_k127_2270989_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1551.0
WLSH2_k127_2270989_1 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 584.0
WLSH2_k127_2270989_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 441.0
WLSH2_k127_2270989_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 394.0
WLSH2_k127_2270989_4 Hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 330.0
WLSH2_k127_2270989_5 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000002859 254.0
WLSH2_k127_2270989_6 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003952 252.0
WLSH2_k127_2270989_7 SapC - - - 0.0000000000000000000000000000000000000000000000000000009237 200.0
WLSH2_k127_2276549_0 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 431.0
WLSH2_k127_2276549_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 369.0
WLSH2_k127_2276549_2 - - - - 0.00000000000000000000000000000000000000000000000000000005579 198.0
WLSH2_k127_2276549_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000004391 117.0
WLSH2_k127_2318568_0 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 552.0
WLSH2_k127_2318568_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000001157 210.0
WLSH2_k127_2318568_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000004038 201.0
WLSH2_k127_2346893_0 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 4.215e-205 646.0
WLSH2_k127_2346893_1 AFG1-like ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 602.0
WLSH2_k127_2346893_2 LemA Family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 358.0
WLSH2_k127_2346893_3 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 312.0
WLSH2_k127_2346893_4 - - - - 0.0001028 45.0
WLSH2_k127_2370165_0 Histidine kinase K07778 - 2.7.13.3 0.0000000000000000000000000000001733 133.0
WLSH2_k127_2370165_1 Histidine kinase K07778 - 2.7.13.3 0.0000000000000000000000000001407 130.0
WLSH2_k127_2406941_0 Diguanylate cyclase - - - 3.117e-201 638.0
WLSH2_k127_2406941_1 Transcriptional regulator - - - 0.0000000000000001878 80.0
WLSH2_k127_2510996_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 9.273e-303 932.0
WLSH2_k127_2510996_1 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 318.0
WLSH2_k127_2510996_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 259.0
WLSH2_k127_2510996_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001165 178.0
WLSH2_k127_254340_0 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 381.0
WLSH2_k127_254340_1 protein-(glutamine-N5) methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 342.0
WLSH2_k127_254340_2 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 330.0
WLSH2_k127_254340_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006022 285.0
WLSH2_k127_254340_4 PFAM Aspartyl Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001236 254.0
WLSH2_k127_254340_5 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000002354 168.0
WLSH2_k127_254340_6 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000002609 142.0
WLSH2_k127_2573034_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.838e-260 807.0
WLSH2_k127_2573034_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 554.0
WLSH2_k127_2573034_2 P-loop ATPase protein family K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 411.0
WLSH2_k127_2573034_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 371.0
WLSH2_k127_2573034_4 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 323.0
WLSH2_k127_2573034_5 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009762 271.0
WLSH2_k127_2573034_6 NusG domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000002578 224.0
WLSH2_k127_2573034_7 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000000000000001799 195.0
WLSH2_k127_2573034_8 cellulose binding - - - 0.000000000000000000000000000000000000000002808 171.0
WLSH2_k127_2573034_9 ABC transporter K06861 - - 0.00000000000000000000000000000000000003378 143.0
WLSH2_k127_2610632_0 Asparagine synthase K01953 - 6.3.5.4 3.107e-309 956.0
WLSH2_k127_2610632_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000007366 205.0
WLSH2_k127_2610632_2 CopG antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000000000003121 158.0
WLSH2_k127_2610632_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000005799 78.0
WLSH2_k127_2610632_4 Peptidase family M23 - - - 0.0001273 45.0
WLSH2_k127_2629261_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1559.0
WLSH2_k127_2629261_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 1.192e-225 728.0
WLSH2_k127_2629261_2 aspartic-type endopeptidase activity K06202,K06985,K19054 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0016530,GO:0016722,GO:0016724,GO:0018282,GO:0018283,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0033554,GO:0034599,GO:0034986,GO:0036211,GO:0042221,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0050896,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071704,GO:0071840,GO:0098771,GO:0140104,GO:1901564 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 520.0
WLSH2_k127_2629261_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 377.0
WLSH2_k127_2629261_4 Frataxin-like domain K06202 - - 0.000000000000000000000000000000000000000000000004566 173.0
WLSH2_k127_2637489_0 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 402.0
WLSH2_k127_2637489_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000567 244.0
WLSH2_k127_2637489_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000008811 238.0
WLSH2_k127_2637489_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000000000007836 102.0
WLSH2_k127_264231_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1041.0
WLSH2_k127_264231_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 447.0
WLSH2_k127_264231_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001405 263.0
WLSH2_k127_2648305_0 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 385.0
WLSH2_k127_2648305_1 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000000923 229.0
WLSH2_k127_2648305_2 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000002702 198.0
WLSH2_k127_2648305_3 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000001044 135.0
WLSH2_k127_2648305_4 - - - - 0.000000000000000000000004461 105.0
WLSH2_k127_2648305_5 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000000001426 98.0
WLSH2_k127_2656596_0 HELICc2 K03722 - 3.6.4.12 0.0 1185.0
WLSH2_k127_2656596_1 PFAM Ankyrin K10799 - 2.4.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 461.0
WLSH2_k127_2656596_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 423.0
WLSH2_k127_2656596_3 PFAM Ankyrin K10799 - 2.4.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 324.0
WLSH2_k127_2656596_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001814 273.0
WLSH2_k127_2656596_5 type II secretion system protein E K02454,K02652,K12276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001162 250.0
WLSH2_k127_2656596_6 LemA Family K03744 - - 0.00000005794 53.0
WLSH2_k127_2663149_0 Histidine kinase K07778 - 2.7.13.3 0.0000000000000000000000000000000005903 146.0
WLSH2_k127_2670324_0 PFAM CHASE2 domain - - - 5.651e-277 862.0
WLSH2_k127_2670324_1 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002379 280.0
WLSH2_k127_2670324_2 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000114 222.0
WLSH2_k127_2670324_3 HD domain - - - 0.0000000000000000000000000006105 114.0
WLSH2_k127_26735_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 445.0
WLSH2_k127_26735_1 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 432.0
WLSH2_k127_26735_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 427.0
WLSH2_k127_26735_3 S-adenosyl-L-methionine-dependent methyltransferase K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 360.0
WLSH2_k127_26735_4 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 302.0
WLSH2_k127_26735_5 - - - - 0.0000000000000000000000000000000000000000000001175 176.0
WLSH2_k127_26735_7 - - - - 0.0000000000000000000002626 98.0
WLSH2_k127_2708402_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 5.736e-217 691.0
WLSH2_k127_2708402_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 286.0
WLSH2_k127_2715562_0 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 512.0
WLSH2_k127_2715562_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000997 147.0
WLSH2_k127_2715562_2 PFAM Hemerythrin HHE cation binding domain protein - - - 0.00000000000000000000000000000004846 127.0
WLSH2_k127_2715562_3 - - - - 0.0000001087 60.0
WLSH2_k127_2779085_0 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 1.171e-226 709.0
WLSH2_k127_2779085_1 Diguanylate cyclase K07216,K13590 - 2.7.7.65 0.00000000000000000000000000001285 122.0
WLSH2_k127_2779085_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000001984 111.0
WLSH2_k127_2793482_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1499.0
WLSH2_k127_2793482_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 514.0
WLSH2_k127_2793482_2 oxygen carrier activity K07216 - - 0.0000000000000000000000000000000000000000002389 162.0
WLSH2_k127_2793482_3 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000001518 123.0
WLSH2_k127_2793482_4 AAA domain - - - 0.000000000006031 66.0
WLSH2_k127_2801163_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 413.0
WLSH2_k127_2801163_1 Ribosomal protein L9, N-terminal domain K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000251 260.0
WLSH2_k127_2801163_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000000000005155 166.0
WLSH2_k127_2849911_0 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 414.0
WLSH2_k127_2849911_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 316.0
WLSH2_k127_288098_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1168.0
WLSH2_k127_288098_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 599.0
WLSH2_k127_288098_2 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002317 273.0
WLSH2_k127_288098_4 heat shock protein binding K05516 - - 0.00000000000000000000002942 111.0
WLSH2_k127_288098_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000004777 76.0
WLSH2_k127_2899809_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 3.403e-237 743.0
WLSH2_k127_2899809_1 - - - - 0.0001357 50.0
WLSH2_k127_2911108_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 2.933e-215 672.0
WLSH2_k127_2911108_1 PFAM type II secretion system protein E K02670 - - 6.729e-201 631.0
WLSH2_k127_2911108_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 323.0
WLSH2_k127_2913076_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 454.0
WLSH2_k127_2913076_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 319.0
WLSH2_k127_2913076_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000377 49.0
WLSH2_k127_2918119_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.247e-293 903.0
WLSH2_k127_2918119_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.949e-291 898.0
WLSH2_k127_2918119_2 N-4 methylation of cytosine K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 462.0
WLSH2_k127_2918119_3 Type II restriction endonuclease EcoO109I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 316.0
WLSH2_k127_2918119_4 Protein of unknown function (DUF3050) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000365 287.0
WLSH2_k127_2918119_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000003372 87.0
WLSH2_k127_2920035_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.088e-237 745.0
WLSH2_k127_2920035_2 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.0000000000000000000000000000000000000000000000000434 181.0
WLSH2_k127_2920035_3 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000001586 173.0
WLSH2_k127_2927154_0 elongation factor Tu domain 2 protein K06207 - - 2.079e-203 634.0
WLSH2_k127_2927154_1 GfdT protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 522.0
WLSH2_k127_2927154_2 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000007543 176.0
WLSH2_k127_2965226_0 Domain of unknown function DUF87 K06915 - - 1.084e-265 825.0
WLSH2_k127_2965226_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.145e-214 668.0
WLSH2_k127_2965226_10 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000000005395 114.0
WLSH2_k127_2965226_11 peptidyl-tyrosine sulfation - - - 0.00003947 48.0
WLSH2_k127_2965226_2 interspecies interaction between organisms - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 365.0
WLSH2_k127_2965226_3 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 349.0
WLSH2_k127_2965226_4 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 326.0
WLSH2_k127_2965226_5 SMART helix-turn-helix domain protein K18831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002917 248.0
WLSH2_k127_2965226_6 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000000000000000000004253 226.0
WLSH2_k127_2965226_7 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.000000000000000000000000000000000000000000000000004825 181.0
WLSH2_k127_2965226_8 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000000000131 133.0
WLSH2_k127_2965226_9 S4 domain K14761 - - 0.00000000000000000000000000008459 116.0
WLSH2_k127_2980718_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.211e-202 634.0
WLSH2_k127_3019864_0 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1112.0
WLSH2_k127_3019864_1 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 472.0
WLSH2_k127_3019864_2 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003987 274.0
WLSH2_k127_3019864_3 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001673 249.0
WLSH2_k127_3019864_4 Cytochrome C biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000003059 211.0
WLSH2_k127_3022918_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 440.0
WLSH2_k127_3022918_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001078 239.0
WLSH2_k127_3022918_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000009512 231.0
WLSH2_k127_3025377_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 6.78e-302 930.0
WLSH2_k127_3025377_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 446.0
WLSH2_k127_3025377_11 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0000001914 53.0
WLSH2_k127_3025377_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 337.0
WLSH2_k127_3025377_3 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000000000000000000002065 228.0
WLSH2_k127_3025377_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000005538 222.0
WLSH2_k127_3025377_5 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000009749 123.0
WLSH2_k127_3025377_6 Protein of unknown function (DUF2628) - - - 0.00000000000000000000005033 106.0
WLSH2_k127_3025377_7 - - - - 0.000000000000009219 80.0
WLSH2_k127_3025377_8 Protein of unknown function (DUF2442) - - - 0.000000000005829 68.0
WLSH2_k127_3025377_9 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.000000005031 60.0
WLSH2_k127_3033455_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 4.647e-319 981.0
WLSH2_k127_3033455_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 5.077e-292 900.0
WLSH2_k127_3033455_10 - - - - 0.0000000000000000000000000000002002 124.0
WLSH2_k127_3033455_12 4Fe-4S binding domain - - - 0.0000000000000000000000000001099 122.0
WLSH2_k127_3033455_13 Nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 0.000000000000000000000005885 100.0
WLSH2_k127_3033455_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.612e-261 819.0
WLSH2_k127_3033455_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 591.0
WLSH2_k127_3033455_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 447.0
WLSH2_k127_3033455_5 Pfam Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 394.0
WLSH2_k127_3033455_6 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 383.0
WLSH2_k127_3033455_7 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 371.0
WLSH2_k127_3033455_9 nitrogen fixation K02593 - - 0.000000000000000000000000000000000001793 140.0
WLSH2_k127_3045790_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 337.0
WLSH2_k127_3045790_1 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 289.0
WLSH2_k127_3045790_2 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000006975 225.0
WLSH2_k127_3045790_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000004242 69.0
WLSH2_k127_3053273_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000001888 131.0
WLSH2_k127_3053273_1 - - - - 0.0000000000000000000000000001099 122.0
WLSH2_k127_3055502_0 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 599.0
WLSH2_k127_3055502_1 Amidohydrolase family K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 373.0
WLSH2_k127_3055502_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000005609 77.0
WLSH2_k127_3055869_0 HI0933-like protein K07007 - - 2.932e-196 622.0
WLSH2_k127_3055869_1 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 316.0
WLSH2_k127_3055869_2 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000000000000000000001269 218.0
WLSH2_k127_3055869_3 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001794 212.0
WLSH2_k127_3055869_4 PFAM HPP family protein K07168 - - 0.00000000000000000000000000000000000000000000000008818 187.0
WLSH2_k127_3055869_5 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000002829 97.0
WLSH2_k127_3055869_6 Invasion gene expression up-regulator, SirB - - - 0.00000000000002527 73.0
WLSH2_k127_3070845_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 3.962e-257 796.0
WLSH2_k127_3070845_1 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 365.0
WLSH2_k127_3070845_2 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000007654 165.0
WLSH2_k127_3088442_0 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 428.0
WLSH2_k127_3088442_1 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 359.0
WLSH2_k127_3088442_2 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008406 268.0
WLSH2_k127_3088442_3 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005543 264.0
WLSH2_k127_3116721_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 544.0
WLSH2_k127_3116721_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 325.0
WLSH2_k127_3116721_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000004402 90.0
WLSH2_k127_3158441_0 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 341.0
WLSH2_k127_3158441_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 326.0
WLSH2_k127_3158441_2 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 313.0
WLSH2_k127_3179648_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1114.0
WLSH2_k127_3179648_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 3.136e-214 668.0
WLSH2_k127_3179648_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 3.531e-196 615.0
WLSH2_k127_3179648_3 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 610.0
WLSH2_k127_3179648_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 415.0
WLSH2_k127_3207011_0 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 589.0
WLSH2_k127_3207011_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 538.0
WLSH2_k127_3207011_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000002857 111.0
WLSH2_k127_324510_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 9.551e-226 703.0
WLSH2_k127_324510_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 607.0
WLSH2_k127_324510_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000000004607 164.0
WLSH2_k127_324510_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000003371 141.0
WLSH2_k127_324510_12 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000002116 123.0
WLSH2_k127_324510_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 571.0
WLSH2_k127_324510_3 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 560.0
WLSH2_k127_324510_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 544.0
WLSH2_k127_324510_5 SMART Resolvase RNase H domain protein fold K06959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 524.0
WLSH2_k127_324510_6 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
WLSH2_k127_324510_7 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001257 276.0
WLSH2_k127_324510_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005897 256.0
WLSH2_k127_324510_9 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000000000000006505 194.0
WLSH2_k127_3246621_0 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 400.0
WLSH2_k127_3246621_1 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000000000000000000000000000000000000001022 172.0
WLSH2_k127_3246621_2 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000000000000000000000000000000000004114 173.0
WLSH2_k127_3279814_0 TIGRFAM cytochrome c oxidase accessory protein CcoG - - - 3.321e-265 822.0
WLSH2_k127_3279814_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000004497 166.0
WLSH2_k127_3279814_2 - - - - 0.00000000152 60.0
WLSH2_k127_3297175_0 Acyl-CoA dehydrogenase, N-terminal domain K06445 - - 0.0 1000.0
WLSH2_k127_3297175_1 TIGRFAM PAS sensor protein - - - 0.0000000000000000287 81.0
WLSH2_k127_3313266_0 PFAM Type II secretion system F domain K02653 - - 4.609e-214 669.0
WLSH2_k127_3313266_1 Domain of unknown function DUF21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 346.0
WLSH2_k127_3313266_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 324.0
WLSH2_k127_3342142_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1147.0
WLSH2_k127_3342142_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 540.0
WLSH2_k127_3342142_2 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000000003045 214.0
WLSH2_k127_3342142_3 TIGRFAM succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000002081 203.0
WLSH2_k127_3342142_4 - - - - 0.000000000000000000000000000000000000000000000000004935 196.0
WLSH2_k127_3342142_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000000000000000001547 142.0
WLSH2_k127_3342142_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000005084 135.0
WLSH2_k127_3342142_7 - - - - 0.000000000000000000000001009 106.0
WLSH2_k127_3342142_8 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000002149 78.0
WLSH2_k127_3342142_9 - - - - 0.00003641 51.0
WLSH2_k127_3346746_0 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 332.0
WLSH2_k127_3346746_1 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001483 264.0
WLSH2_k127_3346746_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 243.0
WLSH2_k127_3346746_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001467 191.0
WLSH2_k127_3346746_5 efflux transmembrane transporter activity K02004 - - 0.000000001921 68.0
WLSH2_k127_3349871_0 Domain of unknown function (DUF3393) K08306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 605.0
WLSH2_k127_3349871_1 Major facilitator Superfamily - - - 0.00000000002812 64.0
WLSH2_k127_3360914_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 1.195e-238 745.0
WLSH2_k127_3360914_1 - - - - 0.00000000241 59.0
WLSH2_k127_3365328_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1232.0
WLSH2_k127_3365328_1 AAA domain - - - 0.0 1199.0
WLSH2_k127_3365328_2 protein conserved in bacteria K07192 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 5.156e-269 836.0
WLSH2_k127_3365328_3 Virulence protein RhuM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 562.0
WLSH2_k127_3365328_4 Protein of unknown function (DUF1449) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004542 269.0
WLSH2_k127_3365328_5 PspA IM30 family protein K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002189 265.0
WLSH2_k127_3365328_6 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000003172 198.0
WLSH2_k127_3365328_7 - - - - 0.000000000000000000000000003896 117.0
WLSH2_k127_3365328_8 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000002017 107.0
WLSH2_k127_3368665_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 564.0
WLSH2_k127_3368665_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 374.0
WLSH2_k127_3368665_2 PFAM Peptidase S24 S26A S26B, conserved region K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 350.0
WLSH2_k127_3368665_3 Protein of unknown function (DUF493) K09158 - - 0.00000000000000000000000000000004427 125.0
WLSH2_k127_3391626_0 HELICc2 K03722 - 3.6.4.12 0.0 1194.0
WLSH2_k127_3391626_1 PFAM Ankyrin K10799 - 2.4.2.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 308.0
WLSH2_k127_3391626_2 type II secretion system protein E K02454,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 243.0
WLSH2_k127_3403667_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0 1015.0
WLSH2_k127_3403667_1 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 483.0
WLSH2_k127_3403667_2 PFAM thioesterase superfamily protein K10806 - - 0.00000000000000000000000000000000000000000000000000000000000000000009921 232.0
WLSH2_k127_3403667_3 Acyl-CoA dehydrogenase, N-terminal domain K06445 - - 0.000000000000000000000000000000000000000003603 156.0
WLSH2_k127_3403667_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.00000000000000000000000000000000000003381 145.0
WLSH2_k127_3403667_5 Protein of unknown function (DUF1016) - - - 0.0000000000000000188 84.0
WLSH2_k127_3403667_6 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 0.0000000000003316 71.0
WLSH2_k127_3403667_7 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.00000005565 55.0
WLSH2_k127_3403667_8 Belongs to the 'phage' integrase family K04763 - - 0.00000009838 55.0
WLSH2_k127_3403667_9 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00009551 44.0
WLSH2_k127_3404501_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 605.0
WLSH2_k127_3404501_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 317.0
WLSH2_k127_3404501_2 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003735 261.0
WLSH2_k127_3404501_3 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001821 253.0
WLSH2_k127_3404501_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000193 116.0
WLSH2_k127_3407_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 7.84e-213 666.0
WLSH2_k127_3407_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 527.0
WLSH2_k127_3407_2 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 501.0
WLSH2_k127_3407_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 444.0
WLSH2_k127_3407_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 443.0
WLSH2_k127_3407_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 338.0
WLSH2_k127_3407_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 329.0
WLSH2_k127_3417715_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2e-227 713.0
WLSH2_k127_3417715_1 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000002122 188.0
WLSH2_k127_3417966_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1e-323 995.0
WLSH2_k127_3417966_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000000001965 165.0
WLSH2_k127_3437883_0 Putative diguanylate phosphodiesterase - - - 7.838e-314 972.0
WLSH2_k127_3437883_1 Alpha/beta hydrolase family K03928 - 3.1.1.1 6.732e-196 616.0
WLSH2_k127_3437883_10 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.00001183 49.0
WLSH2_k127_3437883_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 467.0
WLSH2_k127_3437883_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 381.0
WLSH2_k127_3437883_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 338.0
WLSH2_k127_3437883_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 303.0
WLSH2_k127_3437883_6 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000001143 200.0
WLSH2_k127_3437883_7 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000000006612 198.0
WLSH2_k127_3443833_0 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 475.0
WLSH2_k127_3443833_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 362.0
WLSH2_k127_3443833_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000001164 239.0
WLSH2_k127_3479348_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 1.575e-229 715.0
WLSH2_k127_3479348_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 517.0
WLSH2_k127_3479348_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 360.0
WLSH2_k127_3479348_3 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000000000000000000000000151 181.0
WLSH2_k127_3479348_4 - - - - 0.000000000000000000000001248 105.0
WLSH2_k127_3488069_0 Ami_3 K01448 - 3.5.1.28 6.683e-213 670.0
WLSH2_k127_3488069_1 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 564.0
WLSH2_k127_3488069_2 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003081 294.0
WLSH2_k127_3488069_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000002598 157.0
WLSH2_k127_3488069_4 CAAX protease self-immunity K07052 - - 0.000000000000000005976 90.0
WLSH2_k127_3493081_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 1.251e-272 848.0
WLSH2_k127_3493081_1 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 607.0
WLSH2_k127_3493081_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 364.0
WLSH2_k127_3493081_3 2Fe-2S iron-sulfur cluster binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 339.0
WLSH2_k127_3493081_4 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000008038 164.0
WLSH2_k127_3493081_5 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000000000000000002935 128.0
WLSH2_k127_3493081_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000001439 128.0
WLSH2_k127_3493081_7 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000533 119.0
WLSH2_k127_3493081_8 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000002551 85.0
WLSH2_k127_3515638_0 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 497.0
WLSH2_k127_3515638_1 TIGRFAM efflux transporter, RND family, MFP subunit K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 310.0
WLSH2_k127_3554705_0 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 363.0
WLSH2_k127_3554705_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 301.0
WLSH2_k127_3554705_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000005193 206.0
WLSH2_k127_3732477_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 418.0
WLSH2_k127_3732477_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 404.0
WLSH2_k127_3732477_2 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000006617 163.0
WLSH2_k127_3732477_3 Preprotein translocase SecG subunit K03075 - - 0.00000000009036 62.0
WLSH2_k127_3740911_0 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 562.0
WLSH2_k127_3740911_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 442.0
WLSH2_k127_3740911_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 323.0
WLSH2_k127_3740911_3 PFAM DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000006566 183.0
WLSH2_k127_3740911_4 PFAM Sporulation domain protein - - - 0.00000000000000000000000000000000000000000000005137 182.0
WLSH2_k127_3740911_5 - - - - 0.0000000000000000000000000000001226 125.0
WLSH2_k127_3743622_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 412.0
WLSH2_k127_3743622_1 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 299.0
WLSH2_k127_3743622_2 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002336 273.0
WLSH2_k127_3743622_3 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000007785 104.0
WLSH2_k127_3774695_0 MacB-like periplasmic core domain K02004 - - 2.76e-217 679.0
WLSH2_k127_3774695_1 MacB-like periplasmic core domain K02004 - - 4.464e-215 673.0
WLSH2_k127_3774695_2 Uncharacterized protein conserved in bacteria (DUF2331) - - - 7.568e-194 610.0
WLSH2_k127_3774695_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 369.0
WLSH2_k127_3774695_4 ABC transporter K02003 - - 0.00000000006239 63.0
WLSH2_k127_3777727_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 2.838e-268 870.0
WLSH2_k127_3777727_1 Surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 546.0
WLSH2_k127_3777727_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 354.0
WLSH2_k127_3777727_3 SMART Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000009462 201.0
WLSH2_k127_3777727_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000000000003026 165.0
WLSH2_k127_3780989_0 Fic/DOC family N-terminal - - - 7.706e-196 616.0
WLSH2_k127_3780989_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 419.0
WLSH2_k127_3780989_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 368.0
WLSH2_k127_3780989_3 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
WLSH2_k127_3780989_4 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000001515 100.0
WLSH2_k127_3787904_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.229e-203 638.0
WLSH2_k127_3787904_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 409.0
WLSH2_k127_3809020_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001729 243.0
WLSH2_k127_3809020_1 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000001256 214.0
WLSH2_k127_3810429_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 582.0
WLSH2_k127_3810429_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000003614 258.0
WLSH2_k127_3810429_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000004225 231.0
WLSH2_k127_3810429_3 copG family - - - 0.00000000000000000000000000000000104 132.0
WLSH2_k127_3810429_4 Protein conserved in bacteria K09803 - - 0.000000000007392 66.0
WLSH2_k127_3812245_0 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 4.766e-311 959.0
WLSH2_k127_3812245_1 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 545.0
WLSH2_k127_3812245_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 346.0
WLSH2_k127_3812245_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000002673 130.0
WLSH2_k127_3824369_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 3.981e-254 806.0
WLSH2_k127_3824369_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 413.0
WLSH2_k127_3824369_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001448 278.0
WLSH2_k127_3824369_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000003689 160.0
WLSH2_k127_3849553_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.938e-286 883.0
WLSH2_k127_3849553_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.521e-245 762.0
WLSH2_k127_3849553_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 456.0
WLSH2_k127_3849553_3 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001189 277.0
WLSH2_k127_3849553_4 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002459 263.0
WLSH2_k127_3849553_5 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000134 247.0
WLSH2_k127_3849553_6 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.0000000000000000000000000000000000000000000000000000000003951 202.0
WLSH2_k127_3894855_0 Peptidase family M48 - - - 7.922e-217 682.0
WLSH2_k127_3894855_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 422.0
WLSH2_k127_3894855_2 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000000002825 129.0
WLSH2_k127_3913411_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1398.0
WLSH2_k127_3915692_0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 5.368e-198 620.0
WLSH2_k127_3915692_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 472.0
WLSH2_k127_3915692_2 Transcriptional regulator K18304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 300.0
WLSH2_k127_3915692_3 PFAM Autoinducer synthesis protein K13060,K13061 - 2.3.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003924 280.0
WLSH2_k127_3919178_0 PFAM response regulator receiver K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 354.0
WLSH2_k127_3919178_1 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 295.0
WLSH2_k127_3919178_2 Dihaem cytochrome c - - - 0.000000000000000000000000000000000000000000000000000006587 195.0
WLSH2_k127_3924919_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1058.0
WLSH2_k127_3924919_1 DAHP synthetase I family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 544.0
WLSH2_k127_3924919_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 500.0
WLSH2_k127_3926829_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 5.311e-299 919.0
WLSH2_k127_3926829_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 6.581e-274 845.0
WLSH2_k127_3947864_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005892 425.0
WLSH2_k127_3947864_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 388.0
WLSH2_k127_3947864_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000001203 190.0
WLSH2_k127_3947864_3 - - - - 0.0000000000000000001835 97.0
WLSH2_k127_3947864_4 PFAM DNA polymerase, beta domain protein region - - - 0.000000000001839 70.0
WLSH2_k127_3956186_0 Threonine synthase N terminus K01733 - 4.2.3.1 2.313e-200 625.0
WLSH2_k127_3956186_1 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 502.0
WLSH2_k127_3956186_2 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 343.0
WLSH2_k127_3956186_3 Endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000000000000000001005 154.0
WLSH2_k127_3956186_4 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000002465 154.0
WLSH2_k127_3998670_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 1.187e-214 668.0
WLSH2_k127_3998670_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 390.0
WLSH2_k127_3998670_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000005996 227.0
WLSH2_k127_3998670_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000008121 133.0
WLSH2_k127_3998670_4 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000007185 124.0
WLSH2_k127_3998670_5 SpoVT AbrB K18829 - - 0.00000000000000000000000001052 112.0
WLSH2_k127_4048376_0 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 5.818e-210 657.0
WLSH2_k127_4048376_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 371.0
WLSH2_k127_4048376_3 - - - - 0.0000007365 52.0
WLSH2_k127_4048376_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00003259 46.0
WLSH2_k127_4141295_0 TonB dependent receptor K02014 - - 4.07e-310 962.0
WLSH2_k127_4141295_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.205e-308 953.0
WLSH2_k127_4141295_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001 245.0
WLSH2_k127_4141295_3 Cell division protein ZapA K09888 - - 0.0000000000000000000000000000000000000000000000000001243 190.0
WLSH2_k127_4141295_4 EVE domain - - - 0.000000000000000000000000000000003069 128.0
WLSH2_k127_4141295_5 - - - - 0.0000000000000000000000002017 106.0
WLSH2_k127_415224_0 histidine kinase A domain protein - - - 8.408e-205 653.0
WLSH2_k127_415224_1 Periplasmic binding protein LacI transcriptional regulator K11930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 421.0
WLSH2_k127_4156154_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 477.0
WLSH2_k127_4156154_1 regulator K18831 - - 0.0000000000000000000000000000000000000000000000000000000000000001119 222.0
WLSH2_k127_4156154_2 - - - - 0.0000000000000000000000000000000000000000000000000000001719 198.0
WLSH2_k127_4156154_3 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.0000000000000000000000000000000000000000000000000007237 184.0
WLSH2_k127_4156154_4 PFAM AsmA family protein K07289 - - 0.0002323 46.0
WLSH2_k127_4187738_0 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 361.0
WLSH2_k127_4187738_1 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 319.0
WLSH2_k127_4187738_2 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000006221 188.0
WLSH2_k127_4187738_3 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000006941 159.0
WLSH2_k127_4187738_4 - - - - 0.00000000000000000000000000000000001072 140.0
WLSH2_k127_4187738_5 TfoX C-terminal domain K07343 - - 0.0000000000000000000000004479 107.0
WLSH2_k127_4187738_6 - - - - 0.0000002055 54.0
WLSH2_k127_4210322_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 582.0
WLSH2_k127_4210322_1 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 363.0
WLSH2_k127_4210322_2 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 287.0
WLSH2_k127_4210322_3 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008777 230.0
WLSH2_k127_4213596_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 563.0
WLSH2_k127_4213596_1 - - - - 0.000000000000009873 80.0
WLSH2_k127_4213596_2 Protein of unknown function (DUF721) - - - 0.000000000003955 68.0
WLSH2_k127_4213596_3 - - - - 0.0000004597 58.0
WLSH2_k127_4240283_0 Part of a membrane complex involved in electron transport K03615 - - 1.508e-259 803.0
WLSH2_k127_4240283_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169,K03737 - 1.2.7.1 1.006e-229 716.0
WLSH2_k127_4240283_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 605.0
WLSH2_k127_4240283_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 434.0
WLSH2_k127_4240283_4 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 388.0
WLSH2_k127_4240283_5 FMN_bind K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 364.0
WLSH2_k127_4240283_6 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 326.0
WLSH2_k127_4264587_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.406e-254 787.0
WLSH2_k127_4264587_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 472.0
WLSH2_k127_4266485_0 PFAM Spermine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 302.0
WLSH2_k127_4266485_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000003034 242.0
WLSH2_k127_4266485_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000001431 192.0
WLSH2_k127_4266485_3 oxidoreductase K06940 - - 0.000000000000000000000000000000000000000000000000000007253 190.0
WLSH2_k127_4266864_0 PFAM Pyruvate kinase barrel K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 411.0
WLSH2_k127_4266864_1 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006193 274.0
WLSH2_k127_4266864_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0001857 44.0
WLSH2_k127_4287001_0 PFAM Dinitrogenase reductase ADP-ribosyltransferase K05951 - 2.4.2.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 512.0
WLSH2_k127_4287001_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002042 282.0
WLSH2_k127_4287001_11 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000007248 106.0
WLSH2_k127_4287001_12 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.0000000001619 61.0
WLSH2_k127_4287001_2 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004659 276.0
WLSH2_k127_4287001_3 nucleic acid-binding protein, contains PIN domain - - - 0.00000000000000000000000000000000000000000000000000000000000008602 217.0
WLSH2_k127_4287001_4 - - - - 0.0000000000000000000000000000000000000000000000000000000132 201.0
WLSH2_k127_4287001_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000005925 169.0
WLSH2_k127_4287001_6 addiction module antidote protein - - - 0.00000000000000000000000000000000000000002083 154.0
WLSH2_k127_4287001_7 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000559 152.0
WLSH2_k127_4287001_8 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000000001229 143.0
WLSH2_k127_4287001_9 prlF antitoxin for toxin YhaV_toxin - - - 0.0000000000000000000000000000000000002706 141.0
WLSH2_k127_4310650_0 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 325.0
WLSH2_k127_4310650_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 302.0
WLSH2_k127_4310650_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 290.0
WLSH2_k127_4310650_3 PFAM PEGA domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 297.0
WLSH2_k127_4310650_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000008012 142.0
WLSH2_k127_431333_0 MltA specific insert domain K08304 - - 1.165e-201 633.0
WLSH2_k127_431333_1 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000000000000000001036 222.0
WLSH2_k127_431333_2 - - - - 0.0000000000000000000000000000188 121.0
WLSH2_k127_4418220_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 464.0
WLSH2_k127_4418220_1 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001232 270.0
WLSH2_k127_4418220_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 261.0
WLSH2_k127_4418220_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000000000001078 233.0
WLSH2_k127_4418220_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000003992 192.0
WLSH2_k127_4418220_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000008092 178.0
WLSH2_k127_4496116_2 - - - - 0.0000000000000000000000000000000000000000000001482 173.0
WLSH2_k127_4496116_3 - - - - 0.0000000000000000000000000000000001367 136.0
WLSH2_k127_4496116_4 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000004692 134.0
WLSH2_k127_4496116_5 Protein of unknown function (DUF433) - - - 0.00000000000000000000002922 100.0
WLSH2_k127_452409_0 Nif-specific regulatory protein K02584 - - 2.456e-303 936.0
WLSH2_k127_452409_1 PAS PAC sensor signal transduction histidine kinase K05962 - 2.7.13.1 4.482e-263 817.0
WLSH2_k127_452409_2 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000003806 216.0
WLSH2_k127_452409_3 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000000000000000000001837 154.0
WLSH2_k127_452409_4 Part of a membrane complex involved in electron transport K03617 - - 0.000000000001884 72.0
WLSH2_k127_452409_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.00004328 51.0
WLSH2_k127_454851_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 3.456e-298 924.0
WLSH2_k127_454851_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 565.0
WLSH2_k127_454851_2 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000001599 170.0
WLSH2_k127_454851_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000000002607 145.0
WLSH2_k127_454851_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000003016 65.0
WLSH2_k127_4562475_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 488.0
WLSH2_k127_4562475_1 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 377.0
WLSH2_k127_4562475_2 Histidine kinase - - - 0.000000000000000000000000000000002465 131.0
WLSH2_k127_4598940_0 SMART RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000000000000000000000000000000001815 208.0
WLSH2_k127_4598940_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000007378 141.0
WLSH2_k127_4598940_2 Protein of unknown function (DUF3313) - - - 0.000000000000000000000002621 113.0
WLSH2_k127_4648171_0 SMART heat shock protein DnaJ domain protein K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 406.0
WLSH2_k127_4648171_1 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 308.0
WLSH2_k127_4648171_2 Lipase (class 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007507 277.0
WLSH2_k127_4648171_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 225.0
WLSH2_k127_4714576_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 387.0
WLSH2_k127_4714576_1 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000000005342 158.0
WLSH2_k127_4714576_2 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000005669 104.0
WLSH2_k127_4714576_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000457 72.0
WLSH2_k127_472280_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.909e-255 792.0
WLSH2_k127_472280_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 345.0
WLSH2_k127_472280_2 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000000000000000000000111 152.0
WLSH2_k127_472280_3 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000001015 102.0
WLSH2_k127_4745039_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1212.0
WLSH2_k127_4745039_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 342.0
WLSH2_k127_4766467_0 Part of a membrane complex involved in electron transport K03615 - - 2.797e-218 692.0
WLSH2_k127_4766467_1 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 544.0
WLSH2_k127_4766467_2 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 356.0
WLSH2_k127_4766467_3 DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 362.0
WLSH2_k127_4766467_4 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 348.0
WLSH2_k127_4766467_5 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 316.0
WLSH2_k127_4766467_6 - - - - 0.00000000000000000000000000000000000000000000000000000003683 198.0
WLSH2_k127_4766467_7 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000049 110.0
WLSH2_k127_4784744_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.1e-285 884.0
WLSH2_k127_4784744_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 477.0
WLSH2_k127_4784744_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 355.0
WLSH2_k127_4784744_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000000000001286 195.0
WLSH2_k127_4784744_4 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000004648 80.0
WLSH2_k127_481868_0 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 0.0 1078.0
WLSH2_k127_481868_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 1.354e-265 823.0
WLSH2_k127_481868_2 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 579.0
WLSH2_k127_481868_3 PFAM permease YjgP YjgQ family protein K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 556.0
WLSH2_k127_481868_4 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 289.0
WLSH2_k127_481868_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006163 266.0
WLSH2_k127_481868_6 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000004717 218.0
WLSH2_k127_481868_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000004599 173.0
WLSH2_k127_481868_8 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000000000000005524 140.0
WLSH2_k127_4838175_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 7.382e-259 805.0
WLSH2_k127_4838175_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.286e-208 656.0
WLSH2_k127_488037_0 PFAM aminotransferase class I and II K00812 - 2.6.1.1 2.345e-228 713.0
WLSH2_k127_488037_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 474.0
WLSH2_k127_488037_2 translation initiation factor activity - - - 0.000000000000000000000000000000000000002692 151.0
WLSH2_k127_488037_3 oligosaccharyl transferase activity - - - 0.0005763 44.0
WLSH2_k127_4891347_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 556.0
WLSH2_k127_4891347_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 399.0
WLSH2_k127_4891347_2 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000000000000006568 189.0
WLSH2_k127_49080_0 Beta-eliminating lyase K04487 - 2.8.1.7 4.948e-241 749.0
WLSH2_k127_49080_1 HMGL-like K02594 - 2.3.3.14 5.831e-206 644.0
WLSH2_k127_49080_10 NifU-like domain K13819 - - 0.0000000000001996 69.0
WLSH2_k127_49080_2 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 448.0
WLSH2_k127_49080_3 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 428.0
WLSH2_k127_49080_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001536 268.0
WLSH2_k127_49080_5 NifZ domain K02597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006636 257.0
WLSH2_k127_49080_6 PIN domain - - - 0.00000000000000000000000000000000000000000000000000000000000003286 216.0
WLSH2_k127_49080_7 Nitrogen fixation protein NifW K02595 - - 0.000000000000000000000000000000000000000000000000009463 181.0
WLSH2_k127_49080_8 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000001221 146.0
WLSH2_k127_49080_9 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000002369 145.0
WLSH2_k127_490813_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.976e-217 679.0
WLSH2_k127_490813_1 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 597.0
WLSH2_k127_490813_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 522.0
WLSH2_k127_490813_3 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 433.0
WLSH2_k127_490813_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 328.0
WLSH2_k127_490813_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009002 277.0
WLSH2_k127_4970851_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 625.0
WLSH2_k127_4970851_1 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 511.0
WLSH2_k127_4970851_10 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
WLSH2_k127_4970851_11 Pfam cytochrome c K17230 - - 0.000000000000000000000000000000000000000000000000000000000454 209.0
WLSH2_k127_4970851_12 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000001983 138.0
WLSH2_k127_4970851_13 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000001087 124.0
WLSH2_k127_4970851_14 PFAM NapC NirT cytochrome c K02569 - - 0.0000000006958 70.0
WLSH2_k127_4970851_15 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000001315 59.0
WLSH2_k127_4970851_16 3',5'-cyclic-GMP phosphodiesterase activity K18283 GO:0000122,GO:0000166,GO:0000302,GO:0001101,GO:0001568,GO:0001885,GO:0001944,GO:0002064,GO:0002082,GO:0002237,GO:0002376,GO:0002520,GO:0002521,GO:0002573,GO:0003008,GO:0003013,GO:0003018,GO:0003158,GO:0003170,GO:0003205,GO:0003231,GO:0003279,GO:0003281,GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0004118,GO:0005102,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005743,GO:0005759,GO:0005783,GO:0005794,GO:0005829,GO:0005886,GO:0006139,GO:0006140,GO:0006152,GO:0006163,GO:0006195,GO:0006198,GO:0006355,GO:0006357,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006935,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007186,GO:0007187,GO:0007188,GO:0007193,GO:0007275,GO:0007507,GO:0007568,GO:0007602,GO:0007610,GO:0007635,GO:0008015,GO:0008081,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0008340,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009167,GO:0009169,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009268,GO:0009314,GO:0009410,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009605,GO:0009606,GO:0009607,GO:0009612,GO:0009617,GO:0009628,GO:0009636,GO:0009719,GO:0009888,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010259,GO:0010446,GO:0010468,GO:0010469,GO:0010556,GO:0010558,GO:0010563,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010646,GO:0010647,GO:0010648,GO:0010752,GO:0010753,GO:0010754,GO:0010821,GO:0010941,GO:0012505,GO:0014070,GO:0014074,GO:0015075,GO:0015085,GO:0015267,GO:0015318,GO:0016020,GO:0016787,GO:0016788,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019866,GO:0019867,GO:0019904,GO:0019932,GO:0019933,GO:0019934,GO:0019935,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0022898,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030001,GO:0030097,GO:0030099,GO:0030154,GO:0030224,GO:0030424,GO:0030425,GO:0030545,GO:0030551,GO:0030552,GO:0030553,GO:0030554,GO:0030855,GO:0030911,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031347,GO:0031349,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0032101,GO:0032103,GO:0032386,GO:0032387,GO:0032409,GO:0032410,GO:0032412,GO:0032413,GO:0032496,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032879,GO:0032880,GO:0033043,GO:0033157,GO:0033158,GO:0033159,GO:0033993,GO:0034097,GO:0034220,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0035556,GO:0035690,GO:0035904,GO:0036004,GO:0036005,GO:0036006,GO:0036094,GO:0036477,GO:0040008,GO:0040011,GO:0040012,GO:0040014,GO:0040017,GO:0040018,GO:0042056,GO:0042221,GO:0042278,GO:0042306,GO:0042308,GO:0042325,GO:0042326,GO:0042330,GO:0042454,GO:0042493,GO:0042542,GO:0042578,GO:0042734,GO:0042802,GO:0042803,GO:0042995,GO:0043005,GO:0043114,GO:0043116,GO:0043117,GO:0043167,GO:0043168,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043269,GO:0043271,GO:0043467,GO:0043577,GO:0043949,GO:0043951,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044302,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045121,GO:0045202,GO:0045446,GO:0045892,GO:0045927,GO:0045934,GO:0045936,GO:0045980,GO:0046037,GO:0046038,GO:0046058,GO:0046068,GO:0046069,GO:0046128,GO:0046130,GO:0046434,GO:0046483,GO:0046662,GO:0046677,GO:0046683,GO:0046700,GO:0046822,GO:0046823,GO:0046873,GO:0046983,GO:0047555,GO:0048018,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048520,GO:0048522,GO:0048523,GO:0048534,GO:0048583,GO:0048584,GO:0048585,GO:0048638,GO:0048639,GO:0048731,GO:0048856,GO:0048869,GO:0050727,GO:0050729,GO:0050789,GO:0050793,GO:0050794,GO:0050795,GO:0050896,GO:0050918,GO:0050920,GO:0050921,GO:0051049,GO:0051051,GO:0051094,GO:0051128,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051223,GO:0051224,GO:0051234,GO:0051239,GO:0051240,GO:0051252,GO:0051253,GO:0051591,GO:0051606,GO:0051704,GO:0051707,GO:0051716,GO:0055085,GO:0055086,GO:0060255,GO:0060341,GO:0060429,GO:0060548,GO:0060840,GO:0060976,GO:0061028,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070305,GO:0070482,GO:0070588,GO:0070838,GO:0070848,GO:0070887,GO:0071214,GO:0071216,GO:0071219,GO:0071222,GO:0071260,GO:0071310,GO:0071320,GO:0071321,GO:0071345,GO:0071363,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071496,GO:0071559,GO:0071560,GO:0071704,GO:0071944,GO:0072358,GO:0072359,GO:0072511,GO:0072521,GO:0072523,GO:0080090,GO:0080134,GO:0090087,GO:0090317,GO:0090324,GO:0097011,GO:0097012,GO:0097060,GO:0097159,GO:0097367,GO:0097447,GO:0097457,GO:0097458,GO:0098588,GO:0098589,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098772,GO:0098793,GO:0098805,GO:0098857,GO:0104004,GO:0120025,GO:0120038,GO:1900180,GO:1900181,GO:1900542,GO:1900543,GO:1901046,GO:1901068,GO:1901069,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901419,GO:1901421,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902159,GO:1902160,GO:1902531,GO:1902532,GO:1902533,GO:1902679,GO:1903131,GO:1903506,GO:1903507,GO:1903578,GO:1903579,GO:1903827,GO:1903828,GO:1904589,GO:1904590,GO:1904612,GO:1904613,GO:1904880,GO:1904950,GO:1905957,GO:1905959,GO:1990834,GO:2000112,GO:2000113,GO:2000241,GO:2000243,GO:2001141 3.1.4.17 0.000002021 58.0
WLSH2_k127_4970851_17 PFAM Transposase, IS4-like - - - 0.00001129 53.0
WLSH2_k127_4970851_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 436.0
WLSH2_k127_4970851_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 426.0
WLSH2_k127_4970851_4 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 421.0
WLSH2_k127_4970851_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 355.0
WLSH2_k127_4970851_6 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 304.0
WLSH2_k127_4970851_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 302.0
WLSH2_k127_4970851_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 293.0
WLSH2_k127_4970851_9 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 292.0
WLSH2_k127_4975643_0 Threonyl and Alanyl tRNA synthetase second additional domain K01868 - 6.1.1.3 0.0 1087.0
WLSH2_k127_4975643_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 328.0
WLSH2_k127_4975643_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000000000003901 217.0
WLSH2_k127_4975643_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000000003805 119.0
WLSH2_k127_4984966_0 C-terminal, D2-small domain, of ClpB protein - - - 7.642e-297 921.0
WLSH2_k127_4984966_1 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 9.504e-257 798.0
WLSH2_k127_4984966_2 4Fe-4S single cluster domain K04068 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 328.0
WLSH2_k127_4984966_3 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 323.0
WLSH2_k127_4984966_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 302.0
WLSH2_k127_4984966_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003054 281.0
WLSH2_k127_4984966_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000002373 166.0
WLSH2_k127_4992204_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003296 282.0
WLSH2_k127_4992204_1 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000001194 204.0
WLSH2_k127_4992204_2 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000002128 183.0
WLSH2_k127_4992204_3 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000175 177.0
WLSH2_k127_500148_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 498.0
WLSH2_k127_500148_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 469.0
WLSH2_k127_5009552_0 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 457.0
WLSH2_k127_5009552_1 Response regulators consisting of a CheY-like receiver domain and a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 422.0
WLSH2_k127_5009552_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000001349 216.0
WLSH2_k127_5009552_3 Histidine kinase K08082 - 2.7.13.3 0.0002798 43.0
WLSH2_k127_5015212_0 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 425.0
WLSH2_k127_5015212_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000002062 221.0
WLSH2_k127_5015212_2 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000001047 176.0
WLSH2_k127_5017348_0 Phytochelatin synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003595 273.0
WLSH2_k127_5017348_1 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005127 253.0
WLSH2_k127_5017348_2 PFAM plasmid stabilization system - - - 0.000000000000000000000000000000000000000000000000000000000006027 208.0
WLSH2_k127_5017348_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000007629 143.0
WLSH2_k127_5017348_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000008147 81.0
WLSH2_k127_5017348_6 Protein of unknown function (DUF3592) - - - 0.0008026 49.0
WLSH2_k127_5019130_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 5.504e-237 735.0
WLSH2_k127_5019130_1 Membrane fusogenic activity K09806 - - 0.000000000000000000000007303 105.0
WLSH2_k127_502980_0 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 8.575e-211 657.0
WLSH2_k127_502980_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 594.0
WLSH2_k127_502980_2 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 515.0
WLSH2_k127_502980_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 422.0
WLSH2_k127_5031095_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 1.316e-213 664.0
WLSH2_k127_5031095_1 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 550.0
WLSH2_k127_5031095_2 4Fe-4S binding domain K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 505.0
WLSH2_k127_5031095_3 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000002038 127.0
WLSH2_k127_5076738_0 MgtE intracellular N domain K06213 - - 6.617e-271 839.0
WLSH2_k127_5076738_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 466.0
WLSH2_k127_5076738_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 406.0
WLSH2_k127_5076738_3 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 391.0
WLSH2_k127_5076738_4 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 332.0
WLSH2_k127_5076738_5 TIGRFAM Addiction module killer protein - - - 0.00000000000000000000000000000000003142 139.0
WLSH2_k127_5076738_6 addiction module antidote protein - - - 0.000000000000000000000000000000002128 131.0
WLSH2_k127_5088710_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1287.0
WLSH2_k127_5088710_1 Chitinase class I K03791 - - 0.000000000756 68.0
WLSH2_k127_5149476_0 serine threonine protein kinase K12132 - 2.7.11.1 1.759e-213 671.0
WLSH2_k127_5149476_1 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000001096 133.0
WLSH2_k127_5149476_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000008898 100.0
WLSH2_k127_5149476_3 membrane - - - 0.000000008116 62.0
WLSH2_k127_5157906_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1300.0
WLSH2_k127_5157906_1 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 368.0
WLSH2_k127_5166213_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.479e-251 781.0
WLSH2_k127_5166213_1 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000006119 211.0
WLSH2_k127_5218600_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.308e-234 730.0
WLSH2_k127_5218600_1 fibronectin type III domain protein K06882 - - 3.566e-215 674.0
WLSH2_k127_5218600_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 606.0
WLSH2_k127_5218600_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000002 167.0
WLSH2_k127_524316_0 Large family of predicted nucleotide-binding domains K07175 - - 5.768e-276 853.0
WLSH2_k127_524316_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000003246 253.0
WLSH2_k127_524316_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000004682 249.0
WLSH2_k127_524316_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000001755 147.0
WLSH2_k127_525293_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 8.092e-261 805.0
WLSH2_k127_525293_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 524.0
WLSH2_k127_525293_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 386.0
WLSH2_k127_525293_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 284.0
WLSH2_k127_525492_0 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 479.0
WLSH2_k127_525492_1 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 353.0
WLSH2_k127_525492_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006953 253.0
WLSH2_k127_525492_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001212 237.0
WLSH2_k127_525492_4 MEKHLA domain - - - 0.000000000000000000000000000000000000000000000000000000000003706 215.0
WLSH2_k127_5259917_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.352e-312 964.0
WLSH2_k127_534194_0 AAA domain - - - 0.0 1278.0
WLSH2_k127_534194_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000834 161.0
WLSH2_k127_534194_2 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000008087 123.0
WLSH2_k127_534194_3 oxygen carrier activity K07216 - - 0.000000000000000000000000001034 114.0
WLSH2_k127_5366017_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 1.149e-249 779.0
WLSH2_k127_5366017_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000006732 193.0
WLSH2_k127_542629_0 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 364.0
WLSH2_k127_542629_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000002306 214.0
WLSH2_k127_542629_2 Histidine kinase - - - 0.0000000000000000000000000002605 120.0
WLSH2_k127_5431980_0 Domain of unknown function (DUF3400) - - - 0.0 1347.0
WLSH2_k127_5435352_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 593.0
WLSH2_k127_5435352_1 LysR substrate binding domain K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 381.0
WLSH2_k127_5435352_2 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 339.0
WLSH2_k127_5435352_3 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 334.0
WLSH2_k127_5435352_4 - - - - 0.0000000000003698 73.0
WLSH2_k127_5447892_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 557.0
WLSH2_k127_5447892_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 390.0
WLSH2_k127_5447892_2 Copper chaperone PCu(A)C K09796 - - 0.000002832 49.0
WLSH2_k127_5477907_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 563.0
WLSH2_k127_5477907_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 563.0
WLSH2_k127_5477907_2 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 331.0
WLSH2_k127_5477907_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000002334 216.0
WLSH2_k127_5494710_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 530.0
WLSH2_k127_5494710_1 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 412.0
WLSH2_k127_5494710_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000002481 208.0
WLSH2_k127_5494710_3 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000002387 156.0
WLSH2_k127_5507386_0 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 1.953e-203 635.0
WLSH2_k127_5507386_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
WLSH2_k127_5507386_2 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000003833 242.0
WLSH2_k127_5512616_0 Domain of unknown function (DUF4139) - - - 1.756e-211 666.0
WLSH2_k127_5512616_1 Inner membrane protein CreD K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 405.0
WLSH2_k127_5512616_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000992 186.0
WLSH2_k127_5512616_3 - - - - 0.0000000000000000000000000000000011 136.0
WLSH2_k127_5512616_4 - - - - 0.0000000000002092 72.0
WLSH2_k127_5514059_0 Nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000006416 180.0
WLSH2_k127_5514059_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000005966 116.0
WLSH2_k127_5517123_0 PFAM major facilitator superfamily MFS_1 K08218 - - 1.866e-251 778.0
WLSH2_k127_5517123_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 2.604e-228 709.0
WLSH2_k127_5517123_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000005547 64.0
WLSH2_k127_5517123_11 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0003761 47.0
WLSH2_k127_5517123_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 573.0
WLSH2_k127_5517123_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 475.0
WLSH2_k127_5517123_4 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 383.0
WLSH2_k127_5517123_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 394.0
WLSH2_k127_5517123_6 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 303.0
WLSH2_k127_5517123_7 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000312 256.0
WLSH2_k127_5517123_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004449 226.0
WLSH2_k127_5517123_9 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000004288 188.0
WLSH2_k127_5560158_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 377.0
WLSH2_k127_5560158_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 375.0
WLSH2_k127_5560158_2 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000009149 133.0
WLSH2_k127_5561551_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 486.0
WLSH2_k127_5561551_1 S-adenosyl-L-methionine-dependent methyltransferase K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 319.0
WLSH2_k127_5563001_0 Transcriptional regulator, LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 518.0
WLSH2_k127_5563001_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 312.0
WLSH2_k127_5563001_2 Belongs to the Dps family K04047 - - 0.0008668 42.0
WLSH2_k127_5570955_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 1.464e-207 647.0
WLSH2_k127_5570955_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 551.0
WLSH2_k127_5570955_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 421.0
WLSH2_k127_5570955_3 CHASE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 335.0
WLSH2_k127_5570955_5 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000003795 212.0
WLSH2_k127_5570955_6 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000000000000000005216 204.0
WLSH2_k127_5570955_7 Periplasmic binding protein LacI transcriptional regulator K11930 - - 0.0000000000000000000000000000000000000000000000000000001554 196.0
WLSH2_k127_5570955_8 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000001017 154.0
WLSH2_k127_5570955_9 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000002853 95.0
WLSH2_k127_5587739_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0 1161.0
WLSH2_k127_5587739_1 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 449.0
WLSH2_k127_5587739_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 366.0
WLSH2_k127_5587739_3 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000003379 207.0
WLSH2_k127_5649165_0 GGDEF domain containing protein - - - 0.0 1378.0
WLSH2_k127_5649165_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 572.0
WLSH2_k127_5649165_2 PFAM Cation H exchanger K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 518.0
WLSH2_k127_5649165_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 485.0
WLSH2_k127_5649165_4 Domain of unknown function (DUF4149) - - - 0.0000000000000000000000000000000000000000000003104 172.0
WLSH2_k127_5649165_5 Uncharacterized conserved protein (DUF2164) - - - 0.000000000000000000000000000007584 124.0
WLSH2_k127_5652541_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 4.857e-230 713.0
WLSH2_k127_5652541_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 582.0
WLSH2_k127_5652541_2 PFAM AIR synthase related protein domain protein K04655 - - 0.00000000000000000000000000000000000000000000000000000000003497 207.0
WLSH2_k127_5652541_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000000000000000000002377 151.0
WLSH2_k127_5656725_0 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 565.0
WLSH2_k127_5656725_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 528.0
WLSH2_k127_5656725_2 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 315.0
WLSH2_k127_5656725_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000002081 59.0
WLSH2_k127_56911_0 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 530.0
WLSH2_k127_56911_1 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000000000001517 206.0
WLSH2_k127_56911_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000131 117.0
WLSH2_k127_5699512_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1035.0
WLSH2_k127_5699512_1 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 286.0
WLSH2_k127_5778348_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 2.636e-240 745.0
WLSH2_k127_5778348_1 Nitrogenase component 1 type Oxidoreductase K02592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 531.0
WLSH2_k127_5799663_0 Collagenase K08303 - - 0.0 1097.0
WLSH2_k127_5799663_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 431.0
WLSH2_k127_5799663_3 Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome - - - 0.00000000004162 69.0
WLSH2_k127_5799663_4 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000008721 70.0
WLSH2_k127_5799663_5 Galactose oxidase, central domain - - - 0.000624 53.0
WLSH2_k127_5826380_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 3.482e-307 946.0
WLSH2_k127_5826380_1 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 2.268e-210 659.0
WLSH2_k127_5826380_2 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 339.0
WLSH2_k127_5826380_3 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000406 281.0
WLSH2_k127_5826380_4 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
WLSH2_k127_5826380_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000131 225.0
WLSH2_k127_5826380_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000002353 191.0
WLSH2_k127_5826380_7 Protein conserved in bacteria - - - 0.000000000000000002705 91.0
WLSH2_k127_5855252_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.668e-267 824.0
WLSH2_k127_5855252_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 469.0
WLSH2_k127_5855252_2 17 kDa surface antigen K06077 - - 0.00000000000000000000000000000000000000000000000000005044 191.0
WLSH2_k127_5890528_0 carbon utilization K12280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 291.0
WLSH2_k127_5890528_1 PFAM type II and III secretion system protein K02453,K12282 - - 0.000000000000000000000000000000000000000000000000000000000001221 223.0
WLSH2_k127_5890528_2 Fimbrial assembly protein (PilN) - - - 0.000000000000000000000000000000000000000000000000004805 184.0
WLSH2_k127_5890528_3 - K12281 - - 0.000000000000000001785 91.0
WLSH2_k127_5891245_0 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 595.0
WLSH2_k127_5891245_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 437.0
WLSH2_k127_5891245_2 - - - - 0.0000000000000000000000000000000000000000000000000000000005981 212.0
WLSH2_k127_5913938_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1137.0
WLSH2_k127_5913938_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 321.0
WLSH2_k127_5913938_2 Pfam Glutaredoxin - - - 0.00000000000000002864 83.0
WLSH2_k127_5936303_0 Diguanylate cyclase K13924 - 2.1.1.80,3.1.1.61 0.0 1513.0
WLSH2_k127_5936303_1 PFAM GGDEF domain containing protein - - - 0.0 1259.0
WLSH2_k127_5936303_2 PFAM NADH Ubiquinone plastoquinone (complex I) - - - 1.013e-221 691.0
WLSH2_k127_5936303_3 crp fnr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 355.0
WLSH2_k127_5936303_4 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 307.0
WLSH2_k127_5936303_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000000000001365 120.0
WLSH2_k127_5936303_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000002799 109.0
WLSH2_k127_5948029_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 391.0
WLSH2_k127_5948029_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 321.0
WLSH2_k127_5948029_2 - - - - 0.0000000000000000000000000006105 114.0
WLSH2_k127_5948029_3 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.00000000000000077 77.0
WLSH2_k127_5955089_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 409.0
WLSH2_k127_5955089_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 315.0
WLSH2_k127_599933_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.168e-294 907.0
WLSH2_k127_599933_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.79e-260 807.0
WLSH2_k127_599933_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 491.0
WLSH2_k127_6011898_0 Aminotransferase class-III K01845 - 5.4.3.8 5.448e-249 771.0
WLSH2_k127_6011898_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 395.0
WLSH2_k127_6011898_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 289.0
WLSH2_k127_6148178_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1153.0
WLSH2_k127_6148178_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 529.0
WLSH2_k127_6148178_2 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000003121 209.0
WLSH2_k127_6148178_3 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000001669 73.0
WLSH2_k127_6170687_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 539.0
WLSH2_k127_6170687_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 442.0
WLSH2_k127_6170687_10 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000000000004273 111.0
WLSH2_k127_6170687_11 elongation factor Tu K02358 - - 0.00000000000000001111 82.0
WLSH2_k127_6170687_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 400.0
WLSH2_k127_6170687_3 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 374.0
WLSH2_k127_6170687_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000001545 234.0
WLSH2_k127_6170687_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000000000000000004554 214.0
WLSH2_k127_6170687_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000003277 199.0
WLSH2_k127_6170687_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000000000000000000000003545 201.0
WLSH2_k127_6170687_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000000003135 187.0
WLSH2_k127_6170687_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000002736 161.0
WLSH2_k127_6218783_0 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 446.0
WLSH2_k127_6218783_1 Ankyrin repeats (many copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 280.0
WLSH2_k127_6218783_2 PFAM cation efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000524 212.0
WLSH2_k127_6218783_3 - - - - 0.0000000000000000000000000000000103 128.0
WLSH2_k127_6218783_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000009566 70.0
WLSH2_k127_6219932_0 histidine kinase A domain protein - - - 1.305e-214 684.0
WLSH2_k127_6219932_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 464.0
WLSH2_k127_6219932_2 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 425.0
WLSH2_k127_6219932_3 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001263 267.0
WLSH2_k127_6219932_4 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000001223 212.0
WLSH2_k127_6225399_0 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 521.0
WLSH2_k127_6225399_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 355.0
WLSH2_k127_6230500_0 Chromate transporter K07240 - - 5.144e-235 733.0
WLSH2_k127_6230500_1 Major Facilitator Superfamily - - - 1.463e-222 694.0
WLSH2_k127_6230500_2 PFAM alanine dehydrogenase PNT domain protein K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 581.0
WLSH2_k127_6230500_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 543.0
WLSH2_k127_6230500_4 2OG-Fe dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 399.0
WLSH2_k127_6230500_5 - - - - 0.00000000000000000000000000000000000000000000000000000000002282 207.0
WLSH2_k127_6230500_6 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000001143 204.0
WLSH2_k127_6230500_7 Transcriptional regulator - - - 0.00000000000000000000000000000000002165 136.0
WLSH2_k127_6230500_8 PIN domain - - - 0.00000000000000000000000000000009488 128.0
WLSH2_k127_6230500_9 SpoVT / AbrB like domain - - - 0.0000000000000000003199 90.0
WLSH2_k127_6230913_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.686e-292 900.0
WLSH2_k127_6230913_1 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 577.0
WLSH2_k127_6230913_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 432.0
WLSH2_k127_6230913_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 435.0
WLSH2_k127_6230913_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 372.0
WLSH2_k127_6230913_5 Amino-transferase class IV K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000297 205.0
WLSH2_k127_6230913_6 - - - - 0.0000001181 54.0
WLSH2_k127_6237973_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1079.0
WLSH2_k127_6237973_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0 1041.0
WLSH2_k127_6237973_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 2.681e-214 670.0
WLSH2_k127_6237973_3 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 565.0
WLSH2_k127_6237973_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 396.0
WLSH2_k127_6237973_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000000000001318 186.0
WLSH2_k127_6237973_6 Pfam:DUF1049 K08992 - - 0.00000000000000000000000000000000000001807 147.0
WLSH2_k127_6237973_7 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000003389 126.0
WLSH2_k127_6237973_8 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00007105 46.0
WLSH2_k127_6245966_0 VirC1 protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 373.0
WLSH2_k127_6245966_1 PFAM cytochrome c class I K08738 - - 0.0000000000000000000000000000000000001788 143.0
WLSH2_k127_6245966_2 Cytochrome c K08738 - - 0.0000000000000000000000002981 115.0
WLSH2_k127_6245966_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000001834 85.0
WLSH2_k127_6248622_0 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 1.625e-311 961.0
WLSH2_k127_6272485_0 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 582.0
WLSH2_k127_6272485_1 receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 350.0
WLSH2_k127_6272485_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
WLSH2_k127_6322372_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000001247 218.0
WLSH2_k127_6322372_1 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000005457 149.0
WLSH2_k127_6322372_2 - - - - 0.00000000000000000004529 98.0
WLSH2_k127_6322372_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000002414 75.0
WLSH2_k127_633779_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.216e-239 743.0
WLSH2_k127_633779_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 5.397e-222 692.0
WLSH2_k127_633779_2 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000004448 226.0
WLSH2_k127_6352009_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1520.0
WLSH2_k127_6352009_1 Protein of unknown function - - - 0.0 1437.0
WLSH2_k127_6352009_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1401.0
WLSH2_k127_6352009_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 596.0
WLSH2_k127_6352009_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 570.0
WLSH2_k127_6352009_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000005914 166.0
WLSH2_k127_6352009_6 Zinc-finger domain - - - 0.0000000000000000000000000000007735 133.0
WLSH2_k127_6369979_0 PFAM Ethanolamine ammonia lyase large subunit K03735 - 4.3.1.7 3.392e-244 762.0
WLSH2_k127_6369979_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124 - - 5.509e-226 709.0
WLSH2_k127_6369979_2 Nuclease-related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 414.0
WLSH2_k127_6369979_3 PFAM Ethanolamine ammonia-lyase light chain K03736 - 4.3.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 333.0
WLSH2_k127_6369979_4 Formate dehydrogenase gamma subunit K00127 - - 0.000000000000000000000000000000000000000001865 160.0
WLSH2_k127_6369979_5 Cupin domain K11312 - - 0.00000000000000000000000000000000000000001438 155.0
WLSH2_k127_6369979_6 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 0.00000000000000009143 80.0
WLSH2_k127_6369979_8 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000003738 56.0
WLSH2_k127_6378129_0 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 515.0
WLSH2_k127_6378129_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000003064 61.0
WLSH2_k127_6414861_0 PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 617.0
WLSH2_k127_6414861_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 325.0
WLSH2_k127_6417032_0 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 1.449e-281 872.0
WLSH2_k127_6417032_1 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 403.0
WLSH2_k127_6417032_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 325.0
WLSH2_k127_656976_0 Belongs to the peptidase S16 family - - - 4.139e-260 806.0
WLSH2_k127_656976_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 504.0
WLSH2_k127_656976_2 HNH endonuclease - - - 0.00000001881 57.0
WLSH2_k127_6583324_0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 469.0
WLSH2_k127_6583324_1 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 344.0
WLSH2_k127_6583324_2 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009813 303.0
WLSH2_k127_6627435_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 1.698e-207 647.0
WLSH2_k127_6627435_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 472.0
WLSH2_k127_6627435_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000418 123.0
WLSH2_k127_6646696_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.756e-265 818.0
WLSH2_k127_6646696_1 DJ-1/PfpI family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 297.0
WLSH2_k127_6646696_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000002565 232.0
WLSH2_k127_6646696_3 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000000000000000000000002357 226.0
WLSH2_k127_6646696_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000000000001531 199.0
WLSH2_k127_6646696_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000000001246 162.0
WLSH2_k127_6646696_6 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000000000000473 105.0
WLSH2_k127_6652919_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 531.0
WLSH2_k127_6652919_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 287.0
WLSH2_k127_6652919_2 Conserved repeat domain K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005123 277.0
WLSH2_k127_6652919_3 Phosphate transporter K03306 - - 0.000000008204 57.0
WLSH2_k127_6680884_0 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 534.0
WLSH2_k127_6680884_1 Putative exonuclease, RdgC K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 468.0
WLSH2_k127_6680884_2 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 443.0
WLSH2_k127_6680884_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 310.0
WLSH2_k127_6680884_4 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 297.0
WLSH2_k127_6680884_5 - - - - 0.0001278 45.0
WLSH2_k127_6685343_0 PFAM ABC transporter related K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 559.0
WLSH2_k127_6685343_1 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 449.0
WLSH2_k127_6685343_2 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 363.0
WLSH2_k127_6685343_3 Serine aminopeptidase, S33 K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 359.0
WLSH2_k127_6685343_4 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000000000000000000000000000000000000000004264 234.0
WLSH2_k127_6685343_5 Histidine kinase K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000001045 212.0
WLSH2_k127_6685343_6 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000001981 197.0
WLSH2_k127_6685343_7 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000006727 177.0
WLSH2_k127_6685343_8 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000000000000000000000002653 168.0
WLSH2_k127_6685343_9 Restriction endonuclease - - - 0.00000000001621 76.0
WLSH2_k127_6685684_0 - - - - 1.981e-196 625.0
WLSH2_k127_6694636_0 Virulence factor membrane-bound polymerase, C-terminal - - - 3.817e-259 811.0
WLSH2_k127_6694636_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 292.0
WLSH2_k127_6694636_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005425 240.0
WLSH2_k127_6694636_3 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000005062 190.0
WLSH2_k127_6694636_4 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000009477 132.0
WLSH2_k127_6694636_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000001105 131.0
WLSH2_k127_6694636_6 Protein of unknown function (DUF2892) - - - 0.00000000000000000006566 92.0
WLSH2_k127_6696850_0 type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 492.0
WLSH2_k127_6696850_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 463.0
WLSH2_k127_6696850_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 377.0
WLSH2_k127_6696850_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 331.0
WLSH2_k127_6696850_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 291.0
WLSH2_k127_6696850_5 cheY-homologous receiver domain K07814 - - 0.000000000000000000000000000000000000000000000000000000001705 216.0
WLSH2_k127_6696850_6 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000001607 182.0
WLSH2_k127_6696850_7 response regulator K03413,K07688 - - 0.0000000000000000000000294 104.0
WLSH2_k127_6696850_8 response regulator - - - 0.0000000000000004033 84.0
WLSH2_k127_6696850_9 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0003156 48.0
WLSH2_k127_6745715_0 COG0574 Phosphoenolpyruvate synthase pyruvate phosphate dikinase K01007,K21787 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 2.098e-204 673.0
WLSH2_k127_6745715_1 fatty-acyl-CoA reductase (alcohol-forming) activity K01007,K18845 - 2.1.1.179,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 500.0
WLSH2_k127_6745715_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 361.0
WLSH2_k127_6745715_3 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 326.0
WLSH2_k127_6745715_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000001203 183.0
WLSH2_k127_6745715_5 Belongs to the CDS family K00981,K19664 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41,2.7.7.67 0.00000000000000000000000000000000000000000000000007104 185.0
WLSH2_k127_6745715_6 unsaturated fatty acid biosynthetic process K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000006937 170.0
WLSH2_k127_6745715_7 Acyl-transferase K00655 - 2.3.1.51 0.00000000000000000000002354 109.0
WLSH2_k127_6800981_0 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase - - - 0.0 1298.0
WLSH2_k127_6800981_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000764 537.0
WLSH2_k127_6800981_2 response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003599 241.0
WLSH2_k127_6800981_3 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000002399 162.0
WLSH2_k127_6800981_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000007836 166.0
WLSH2_k127_6800981_5 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000000000000002692 162.0
WLSH2_k127_6800981_6 addiction module antidote protein HigA K21498 - - 0.00000000000000000000000000000000000000001985 154.0
WLSH2_k127_6800981_8 Transposase IS200 like - - - 0.000000000007962 67.0
WLSH2_k127_6833627_0 Oxidoreductase FAD-binding domain protein K00523,K18248 - 1.17.1.1 1.9e-215 675.0
WLSH2_k127_6833627_1 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 2.056e-200 631.0
WLSH2_k127_6833627_2 Phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 537.0
WLSH2_k127_6833627_3 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003083 278.0
WLSH2_k127_6845063_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 374.0
WLSH2_k127_6845063_1 nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 329.0
WLSH2_k127_6845063_2 Transcriptional regulator K16137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007225 254.0
WLSH2_k127_6845063_3 Sulfurtransferase TusA K04085 - - 0.00000000000000000000000000000000004828 136.0
WLSH2_k127_6857837_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1470.0
WLSH2_k127_6857837_1 SurA N-terminal domain K03770 - 5.2.1.8 1.24e-245 773.0
WLSH2_k127_6857837_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 376.0
WLSH2_k127_6857837_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 351.0
WLSH2_k127_6857837_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000003759 205.0
WLSH2_k127_6857837_5 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000000000000000000000004376 162.0
WLSH2_k127_6857837_6 - - - - 0.0000000000000001436 82.0
WLSH2_k127_6871746_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.566e-238 741.0
WLSH2_k127_6871746_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 460.0
WLSH2_k127_6871746_2 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000000000000002473 172.0
WLSH2_k127_6877064_0 pilus assembly protein FimV K08086 - - 7.051e-221 716.0
WLSH2_k127_6877064_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 413.0
WLSH2_k127_6877064_2 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009024 274.0
WLSH2_k127_6877064_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003292 269.0
WLSH2_k127_690666_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 9.505e-305 938.0
WLSH2_k127_690666_1 V-type proton ATPase subunit E K02121 - - 0.0000000000000000000000000000000000000000000000009465 185.0
WLSH2_k127_690666_2 ATP synthase (F/14-kDa) subunit - - - 0.00000000000000000000000000000000000000000000009174 170.0
WLSH2_k127_6980041_0 Succinyl-CoA ligase like flavodoxin domain - - - 0.0 1189.0
WLSH2_k127_6980041_1 ATP citrate lyase citrate-binding - - - 1.865e-213 668.0
WLSH2_k127_6980041_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 435.0
WLSH2_k127_6980041_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 413.0
WLSH2_k127_6980041_4 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 410.0
WLSH2_k127_6980041_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002583 240.0
WLSH2_k127_6980041_6 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000001711 62.0
WLSH2_k127_7041901_0 PFAM Archaeal ATPase - - - 0.0 1029.0
WLSH2_k127_7041901_1 ATP-dependent peptidase activity K04076,K04770 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 454.0
WLSH2_k127_7041901_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000003482 179.0
WLSH2_k127_7041901_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000002856 165.0
WLSH2_k127_7041901_4 VanZ like family - - - 0.0000000000000000000000001591 110.0
WLSH2_k127_7041901_5 oxygen carrier activity K07216 - - 0.000000000000000000002371 99.0
WLSH2_k127_7041901_6 Universal stress protein family - - - 0.000000000000000000008136 92.0
WLSH2_k127_7044974_0 AAA domain K07028 - - 2.281e-206 651.0
WLSH2_k127_7044974_1 Involved in the tonB-independent uptake of proteins K20276 - - 0.00007719 51.0
WLSH2_k127_7057155_0 AAA domain K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 244.0
WLSH2_k127_7057155_1 Tetratricopeptide repeat K12284 - - 0.00000000000000000000000000000000000000000000000000000000001429 222.0
WLSH2_k127_7057777_0 COG1819 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001067 273.0
WLSH2_k127_7057777_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000002705 186.0
WLSH2_k127_7057777_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000002111 76.0
WLSH2_k127_7059135_0 mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 355.0
WLSH2_k127_7059135_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 335.0
WLSH2_k127_7066145_0 histidine kinase HAMP region domain protein K07711 - 2.7.13.3 9.785e-199 629.0
WLSH2_k127_7066145_1 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 413.0
WLSH2_k127_7074246_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1043.0
WLSH2_k127_7074246_1 Elongator protein 3, MiaB family, Radical SAM - - - 5.213e-218 684.0
WLSH2_k127_7074246_10 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 334.0
WLSH2_k127_7074246_11 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 320.0
WLSH2_k127_7074246_12 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 330.0
WLSH2_k127_7074246_13 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 289.0
WLSH2_k127_7074246_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000393 243.0
WLSH2_k127_7074246_16 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000161 233.0
WLSH2_k127_7074246_17 ketosteroid isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000259 218.0
WLSH2_k127_7074246_18 - - - - 0.0000000000000000000000000000000000000000000000000000000004396 210.0
WLSH2_k127_7074246_19 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000001273 169.0
WLSH2_k127_7074246_2 B12 binding domain - - - 6.528e-213 668.0
WLSH2_k127_7074246_20 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000004951 167.0
WLSH2_k127_7074246_21 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000004584 139.0
WLSH2_k127_7074246_22 - - - - 0.000000000000000002571 97.0
WLSH2_k127_7074246_23 peptidase C14 caspase catalytic subunit p20 - - - 0.00001191 54.0
WLSH2_k127_7074246_3 Elongator protein 3, MiaB family, Radical SAM - - - 1.991e-204 648.0
WLSH2_k127_7074246_4 Major Facilitator Superfamily K08227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 569.0
WLSH2_k127_7074246_5 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 535.0
WLSH2_k127_7074246_6 Transporter associated domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 501.0
WLSH2_k127_7074246_7 S4 RNA-binding domain K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 433.0
WLSH2_k127_7074246_8 GH3 auxin-responsive promoter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 416.0
WLSH2_k127_7074246_9 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 353.0
WLSH2_k127_7079162_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1001.0
WLSH2_k127_7079162_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 448.0
WLSH2_k127_7079162_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 415.0
WLSH2_k127_7079162_3 PFAM import inner membrane translocase subunit Tim44 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 383.0
WLSH2_k127_7079162_4 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 311.0
WLSH2_k127_7079162_5 Pfam Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000004128 235.0
WLSH2_k127_7085174_0 - - - - 3.297e-228 710.0
WLSH2_k127_7085174_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001656 272.0
WLSH2_k127_7085174_2 Protein of unknown function (DUF4242) - - - 0.00000000000000000000000000000000000000000002516 162.0
WLSH2_k127_7113176_0 phosphorelay sensor kinase activity K02342,K02851 - 2.7.7.7,2.7.8.33,2.7.8.35 8.946e-206 651.0
WLSH2_k127_7113176_1 Peptidase family U32 C-terminal domain K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 597.0
WLSH2_k127_7113176_2 Peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 447.0
WLSH2_k127_7113176_3 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 335.0
WLSH2_k127_7113176_4 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007822 274.0
WLSH2_k127_7113176_5 Pathogenicity locus - - - 0.0000000000000000000000000000001552 125.0
WLSH2_k127_7113176_6 AAA domain K07028 - - 0.000000000000000002124 87.0
WLSH2_k127_7116640_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 2.308e-208 651.0
WLSH2_k127_7116640_1 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000001019 166.0
WLSH2_k127_7116640_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000005635 118.0
WLSH2_k127_7116640_3 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000000000000000004807 104.0
WLSH2_k127_7116864_0 Intracellular septation protein A K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 297.0
WLSH2_k127_7116864_1 Belongs to the MsrB Met sulfoxide reductase family K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004533 275.0
WLSH2_k127_7116864_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000001208 241.0
WLSH2_k127_7116864_3 YCII-related domain K09780 - - 0.00000000000000000000000000000000000000000006373 161.0
WLSH2_k127_7116864_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000009939 70.0
WLSH2_k127_7153303_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 1.716e-233 728.0
WLSH2_k127_7153303_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000005413 166.0
WLSH2_k127_7153303_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000006023 57.0
WLSH2_k127_7173887_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1916.0
WLSH2_k127_7173887_1 metal-dependent phosphohydrolase HD sub domain - - - 3.1e-242 758.0
WLSH2_k127_7173887_2 NmrA-like family K19267 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 434.0
WLSH2_k127_7173887_3 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000009567 206.0
WLSH2_k127_7173887_4 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000001887 121.0
WLSH2_k127_7173887_5 - - - - 0.000000005765 64.0
WLSH2_k127_7180293_0 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 547.0
WLSH2_k127_7180293_1 protein encoded in hypervariable junctions of pilus gene clusters - - - 0.000000000000000000000001108 104.0
WLSH2_k127_7191834_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 568.0
WLSH2_k127_7191834_1 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000003829 248.0
WLSH2_k127_7231607_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 544.0
WLSH2_k127_7231607_1 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000003955 213.0
WLSH2_k127_7231607_2 nucleotidyltransferase substrate binding protein, HI0074 family - - - 0.000000000000000000000000000000000000000000000000000000001508 203.0
WLSH2_k127_7231607_3 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000003481 141.0
WLSH2_k127_7240472_0 Sulfate transporter antisigma-factor antagonist STAS - - - 0.0 1074.0
WLSH2_k127_7240472_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.049e-294 910.0
WLSH2_k127_7240472_2 Citrate transporter - - - 4.957e-270 845.0
WLSH2_k127_7240472_3 cytochrome c-type protein K02569 - - 0.0000000000000000000000000000000000000000000000000000000001724 209.0
WLSH2_k127_7240472_4 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000001651 160.0
WLSH2_k127_7240472_5 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000001301 138.0
WLSH2_k127_7240472_6 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000001548 139.0
WLSH2_k127_7300947_0 type III restriction protein res subunit K01153 - 3.1.21.3 0.0 1469.0
WLSH2_k127_7300947_1 type I restriction-modification system K03427 - 2.1.1.72 0.0 1225.0
WLSH2_k127_7300947_2 Putative DNA-binding domain K03655 - 3.6.4.12 3.773e-212 669.0
WLSH2_k127_7300947_3 DNA specificity K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 349.0
WLSH2_k127_7300947_4 ATP synthase subunit C K02124 - - 0.00000000000000000000000000000000000000000000000000000000000000002938 226.0
WLSH2_k127_7300947_5 ATP synthase (F/14-kDa) subunit - - - 0.00000000000000000000000000000000000000000000006688 171.0
WLSH2_k127_7300947_6 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000004403 155.0
WLSH2_k127_7300947_7 V-type proton ATPase subunit E K02121 - - 0.0000000000000044 82.0
WLSH2_k127_7451484_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 538.0
WLSH2_k127_7451484_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 415.0
WLSH2_k127_7451484_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.0000000000000000002587 87.0
WLSH2_k127_7465922_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1189.0
WLSH2_k127_7465922_1 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 1.859e-194 608.0
WLSH2_k127_7465922_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 308.0
WLSH2_k127_7465922_3 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000003897 149.0
WLSH2_k127_7465922_4 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000000000001603 139.0
WLSH2_k127_7465922_5 Flagellar regulator YcgR - - - 0.00000000000000256 85.0
WLSH2_k127_7465922_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000007684 73.0
WLSH2_k127_7483661_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5e-324 1004.0
WLSH2_k127_7483661_1 serine threonine protein kinase K12132 - 2.7.11.1 2.7e-229 715.0
WLSH2_k127_7483661_10 - - - - 0.0000000000000000000000000000000000001607 148.0
WLSH2_k127_7483661_2 PFAM major facilitator superfamily MFS_1 - - - 9.691e-221 691.0
WLSH2_k127_7483661_3 serine threonine protein kinase K12132 - 2.7.11.1 9.589e-215 672.0
WLSH2_k127_7483661_4 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 529.0
WLSH2_k127_7483661_5 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 354.0
WLSH2_k127_7483661_6 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000005915 261.0
WLSH2_k127_7483661_7 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000000000000381 228.0
WLSH2_k127_7483661_8 plasmid maintenance system antidote protein K21498 - - 0.0000000000000000000000000000000000000000000000003327 179.0
WLSH2_k127_7483661_9 Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000000000000000000007976 175.0
WLSH2_k127_7484365_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.4e-292 903.0
WLSH2_k127_7484365_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 538.0
WLSH2_k127_7484365_2 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
WLSH2_k127_7484365_3 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 391.0
WLSH2_k127_7484365_4 TIGRFAM RNA polymerase sigma factor RpoE K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 370.0
WLSH2_k127_7484365_5 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 254.0
WLSH2_k127_7484365_6 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000000000000000000000000000000000000007493 181.0
WLSH2_k127_7484365_7 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000003608 121.0
WLSH2_k127_7484365_8 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K19168 - - 0.0000002642 58.0
WLSH2_k127_7534122_0 DEAD DEAH box helicase domain protein K03654 - 3.6.4.12 0.0 1103.0
WLSH2_k127_7534122_1 Histidine kinase - - - 1.906e-242 766.0
WLSH2_k127_7534122_2 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000003257 234.0
WLSH2_k127_7644809_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 511.0
WLSH2_k127_7644809_1 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000001918 214.0
WLSH2_k127_7644809_2 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000005889 111.0
WLSH2_k127_76697_0 His Kinase A (phosphoacceptor) domain - - - 2.095e-225 727.0
WLSH2_k127_7723265_0 His Kinase A (phosphoacceptor) domain K19661 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 526.0
WLSH2_k127_7723265_1 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000004679 204.0
WLSH2_k127_7723265_2 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000004465 188.0
WLSH2_k127_7723265_3 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000002635 85.0
WLSH2_k127_775681_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 545.0
WLSH2_k127_775681_1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.000000000000000000000000000000000000000000000000000000000000002779 220.0
WLSH2_k127_775681_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000007759 207.0
WLSH2_k127_775681_3 nucleotidyltransferase activity K07076 - - 0.0000000000000000000000002525 109.0
WLSH2_k127_775681_4 HEPN domain - - - 0.0000000000000000000000004708 109.0
WLSH2_k127_7873184_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1134.0
WLSH2_k127_7895289_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 5.56e-272 845.0
WLSH2_k127_7895289_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 301.0
WLSH2_k127_7895289_2 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005529 220.0
WLSH2_k127_7895289_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000003308 173.0
WLSH2_k127_7924588_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 451.0
WLSH2_k127_7924588_1 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 402.0
WLSH2_k127_7924588_10 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000000000000222 154.0
WLSH2_k127_7924588_11 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000000000000003935 144.0
WLSH2_k127_7924588_12 - - - - 0.0000000000000000000001266 98.0
WLSH2_k127_7924588_13 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000006125 60.0
WLSH2_k127_7924588_2 Phosphoesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 384.0
WLSH2_k127_7924588_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 324.0
WLSH2_k127_7924588_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 296.0
WLSH2_k127_7924588_5 TIGRFAM alkylphosphonate utilization operon protein PhnA K06193 - - 0.00000000000000000000000000000000000000000000000000000000000000003319 224.0
WLSH2_k127_7924588_6 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000000006542 214.0
WLSH2_k127_7924588_7 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000003705 197.0
WLSH2_k127_7924588_8 BON domain - - - 0.000000000000000000000000000000000000000000000000004859 186.0
WLSH2_k127_7924588_9 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000000000000000000000000000000188 166.0
WLSH2_k127_7925857_0 Histidine Phosphotransfer domain K02487,K06596 - - 0.0 2109.0
WLSH2_k127_7925857_1 PFAM TrkA-N domain protein K03499 - - 1.766e-262 812.0
WLSH2_k127_7925857_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 5.378e-254 789.0
WLSH2_k127_7925857_3 histidine kinase HAMP region domain protein K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 605.0
WLSH2_k127_7925857_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 299.0
WLSH2_k127_7925857_5 Two component signalling adaptor domain K02659 - - 0.000000000000000000000000000000000000000000000000000000000000000000009716 236.0
WLSH2_k127_7925857_6 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000006215 229.0
WLSH2_k127_7925857_7 response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000000000248 181.0
WLSH2_k127_7928469_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.196e-321 990.0
WLSH2_k127_7928469_1 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008839 260.0
WLSH2_k127_7928469_2 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000000003283 135.0
WLSH2_k127_793401_0 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 1.074e-274 846.0
WLSH2_k127_793401_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 501.0
WLSH2_k127_793401_2 aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 346.0
WLSH2_k127_793401_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
WLSH2_k127_793401_4 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 286.0
WLSH2_k127_793401_5 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001819 282.0
WLSH2_k127_793401_6 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000000000001753 218.0
WLSH2_k127_793401_7 - - - - 0.00000000000000000000000000000002725 126.0
WLSH2_k127_7945375_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1445.0
WLSH2_k127_7945375_1 metal-dependent phosphohydrolase HD sub domain - - - 5.69e-283 876.0
WLSH2_k127_7945375_2 MacB-like periplasmic core domain K02004 - - 8.149e-217 678.0
WLSH2_k127_7945375_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 407.0
WLSH2_k127_7945375_4 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 284.0
WLSH2_k127_7945375_5 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000000000000003241 101.0
WLSH2_k127_7945375_6 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.0000000000000000002211 94.0
WLSH2_k127_7945375_7 pilus assembly protein major pilin PilA K02650 - - 0.00000000000000008629 85.0
WLSH2_k127_7945375_8 Outer membrane lipoprotein-sorting protein - - - 0.00000000000001016 77.0
WLSH2_k127_7949949_0 TOBE domain K02019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 412.0
WLSH2_k127_7949949_1 molybdenum ABC transporter, periplasmic K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 358.0
WLSH2_k127_8008408_0 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 335.0
WLSH2_k127_8008408_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 320.0
WLSH2_k127_8008408_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000003281 125.0
WLSH2_k127_8008408_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.00004342 47.0
WLSH2_k127_8018904_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 499.0
WLSH2_k127_8018904_1 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 427.0
WLSH2_k127_8018904_2 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 327.0
WLSH2_k127_8018904_3 SpoIIAA-like - - - 0.0000000000000004304 78.0
WLSH2_k127_8027276_0 Putative diguanylate phosphodiesterase - - - 0.0 1170.0
WLSH2_k127_8027276_1 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 300.0
WLSH2_k127_8032561_0 Required for chromosome condensation and partitioning K03529 - - 6.188e-313 972.0
WLSH2_k127_8032561_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.139e-292 901.0
WLSH2_k127_8032561_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 284.0
WLSH2_k127_8038406_0 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 361.0
WLSH2_k127_8038406_1 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000000000000000000003294 235.0
WLSH2_k127_8038406_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000002201 161.0
WLSH2_k127_8061421_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009854 274.0
WLSH2_k127_8061421_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002066 271.0
WLSH2_k127_8061421_2 Diguanylate cyclase K20959 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032879,GO:0040012,GO:0040013,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0065007,GO:0071944,GO:1902021,GO:1902201,GO:2000145,GO:2000146 2.7.7.65 0.000000000000000000002262 108.0
WLSH2_k127_8061421_3 TIGRFAM conserved repeat domain - - - 0.0000000000000002675 91.0
WLSH2_k127_8069291_0 PFAM CHAD domain containing protein - - - 2.919e-242 756.0
WLSH2_k127_8069291_1 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 586.0
WLSH2_k127_8069291_2 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 364.0
WLSH2_k127_8069291_3 LemA Family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 320.0
WLSH2_k127_8069291_4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000074 251.0
WLSH2_k127_8069291_5 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000000000000000000000000000000000000000000000000000002345 223.0
WLSH2_k127_8069291_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000009881 50.0
WLSH2_k127_8097344_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 518.0
WLSH2_k127_8097344_1 PFAM Peptidase S24 S26A S26B, conserved region K03503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 288.0
WLSH2_k127_8118581_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 456.0
WLSH2_k127_8118581_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 354.0
WLSH2_k127_8118581_2 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000001069 103.0
WLSH2_k127_8135531_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 431.0
WLSH2_k127_8135531_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000005088 214.0
WLSH2_k127_8135531_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000579 137.0
WLSH2_k127_8135531_3 peptidase S9 - - - 0.0000000000000000000000000000000003387 134.0
WLSH2_k127_8135531_4 hydrolase activity, acting on ester bonds - - - 0.0002798 45.0
WLSH2_k127_8159346_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1157.0
WLSH2_k127_8159346_1 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000004866 170.0
WLSH2_k127_8235165_0 HNH endonuclease K09952 - - 0.0 1428.0
WLSH2_k127_8235165_1 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 444.0
WLSH2_k127_8235165_2 CRISPR associated protein Cas2 K09951 - - 0.000000000000000000000000000000000000000000000567 169.0
WLSH2_k127_8249065_0 Ammonium Transporter Family K03320 - - 8.65e-220 690.0
WLSH2_k127_8249065_1 Belongs to the P(II) protein family K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000000000001426 219.0
WLSH2_k127_8256013_0 TIGRFAM 2-methylcitrate synthase citrate synthase II K01659 - 2.3.3.5 2.833e-220 687.0
WLSH2_k127_8256013_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 511.0
WLSH2_k127_8256013_2 PFAM GntR domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 387.0
WLSH2_k127_8256013_3 2-methylcitrate dehydratase K01720 - 4.2.1.79 0.00000000000001856 73.0
WLSH2_k127_8288842_0 May be involved in recombinational repair of damaged DNA K03631 - - 3.397e-272 845.0
WLSH2_k127_8288842_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 428.0
WLSH2_k127_8288842_2 nuclease activity - - - 0.00000000000000000000000000003928 121.0
WLSH2_k127_829930_0 PFAM glycosyl transferase group 1 - - - 3.569e-220 688.0
WLSH2_k127_829930_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 511.0
WLSH2_k127_829930_2 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 388.0
WLSH2_k127_829930_3 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 286.0
WLSH2_k127_829930_4 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.0003405 46.0
WLSH2_k127_8332235_0 LysM domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 578.0
WLSH2_k127_8332235_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 0.000000000000000000000000000000000001227 139.0
WLSH2_k127_8344437_0 MscS Mechanosensitive ion channel - - - 4.098e-247 772.0
WLSH2_k127_8344437_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 576.0
WLSH2_k127_8344437_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 321.0
WLSH2_k127_8344437_4 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000000000000000000000000000000001378 151.0
WLSH2_k127_8344437_5 General secretion pathway K02462 - - 0.0000000000000000000000000000000003712 139.0
WLSH2_k127_8349735_0 SMART von Willebrand factor type A - - - 0.0 1146.0
WLSH2_k127_8349735_1 ATPase associated with various cellular activities AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 293.0
WLSH2_k127_8350976_0 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 362.0
WLSH2_k127_8350976_1 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 353.0
WLSH2_k127_8350976_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005018 257.0
WLSH2_k127_8350976_3 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000003196 118.0
WLSH2_k127_8350976_4 Histidine kinase K02487,K06596 - - 0.000000000000000005509 84.0
WLSH2_k127_8366557_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1037.0
WLSH2_k127_8366557_1 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.000000000000000000000000000000000000000000000000000000000000003498 220.0
WLSH2_k127_8366557_2 HipA N-terminal domain K07154 - 2.7.11.1 0.0000000000000000000000000000000003372 135.0
WLSH2_k127_8366557_3 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000001949 128.0
WLSH2_k127_8380657_0 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 2.668e-305 939.0
WLSH2_k127_8380657_1 glutamate synthase alpha subunit domain protein K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001222 248.0
WLSH2_k127_8380657_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000004178 80.0
WLSH2_k127_8391267_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.324e-315 979.0
WLSH2_k127_8391267_1 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 558.0
WLSH2_k127_8391267_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 393.0
WLSH2_k127_8391267_3 - - - - 0.000000000000000000000000000003695 127.0
WLSH2_k127_8402094_0 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 594.0
WLSH2_k127_8402094_1 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 482.0
WLSH2_k127_8402094_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 285.0
WLSH2_k127_8402094_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003401 254.0
WLSH2_k127_8402094_5 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000002415 121.0
WLSH2_k127_8402094_6 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000002017 107.0
WLSH2_k127_8402094_7 TIGRFAM heavy metal efflux pump, CzcA family K07787 - - 0.0005401 43.0
WLSH2_k127_8430034_0 - - - - 4.345e-258 798.0
WLSH2_k127_8430034_1 metal-dependent phosphohydrolase HD sub domain K07814 - - 1.27e-217 683.0
WLSH2_k127_8430034_2 anti-sigma regulatory factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 441.0
WLSH2_k127_8430034_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 369.0
WLSH2_k127_8430034_5 - - - - 0.000000000000000000000000000000000000000002608 158.0
WLSH2_k127_8430034_6 - K17762 - - 0.00000000000000000000000000000001294 136.0
WLSH2_k127_8440544_0 MoeA C-terminal region (domain IV) K03750,K07219 - 2.10.1.1 6.986e-215 672.0
WLSH2_k127_8440544_1 Molybdopterin guanine dinucleotide synthesis protein B K03753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 291.0
WLSH2_k127_8440544_10 - - - - 0.00000000000000000000000001222 113.0
WLSH2_k127_8440544_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000002521 79.0
WLSH2_k127_8440544_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 297.0
WLSH2_k127_8440544_3 MoaC family K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 284.0
WLSH2_k127_8440544_4 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001264 282.0
WLSH2_k127_8440544_5 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003882 266.0
WLSH2_k127_8440544_6 Histidine biosynthesis protein - - - 0.00000000000000000000000000000000000000000006187 168.0
WLSH2_k127_8440544_7 Domain of unknown function (DUF309) - - - 0.0000000000000000000000000000000000001374 145.0
WLSH2_k127_8440544_8 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000006853 134.0
WLSH2_k127_8440544_9 ThiS family K03636 - - 0.00000000000000000000000000000007583 126.0
WLSH2_k127_8460676_0 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 8.941e-238 739.0
WLSH2_k127_8460676_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 590.0
WLSH2_k127_8460676_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 526.0
WLSH2_k127_8460676_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 372.0
WLSH2_k127_8467726_0 PFAM TrkA-N domain protein K03499 - - 1.315e-259 803.0
WLSH2_k127_8467726_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 4.634e-243 757.0
WLSH2_k127_8467726_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 301.0
WLSH2_k127_8467726_3 Two component signalling adaptor domain K02659 - - 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
WLSH2_k127_8467726_4 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000007156 229.0
WLSH2_k127_8467726_5 response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000000003724 183.0
WLSH2_k127_8476115_0 Part of a membrane complex involved in electron transport K03615 - - 4.397e-209 654.0
WLSH2_k127_8476115_1 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 293.0
WLSH2_k127_8476115_2 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 289.0
WLSH2_k127_8498824_0 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 594.0
WLSH2_k127_8498824_1 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003954 261.0
WLSH2_k127_8498824_2 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000117 171.0
WLSH2_k127_8498824_3 - - - - 0.0000000000000000000000000000000000000000000006706 168.0
WLSH2_k127_8538009_0 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 1.445e-252 781.0
WLSH2_k127_8538009_1 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000002362 134.0
WLSH2_k127_8538009_2 - - - - 0.000000000000000000000000000000006036 130.0
WLSH2_k127_8538009_3 Protein of unknown function (DUF2283) - - - 0.00000000000000000000009296 100.0
WLSH2_k127_8542892_0 SEC-C motif domain protein K07039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 417.0
WLSH2_k127_8542892_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 388.0
WLSH2_k127_8542892_2 domain protein - - - 0.000000000000000000000000000000001889 141.0
WLSH2_k127_857038_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1341.0
WLSH2_k127_857038_1 AAA domain K16898 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 524.0
WLSH2_k127_857038_2 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 485.0
WLSH2_k127_857038_3 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 385.0
WLSH2_k127_857038_4 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000002166 243.0
WLSH2_k127_857038_5 Nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001802 228.0
WLSH2_k127_857038_6 addiction module antidote protein - - - 0.00000000000000000000000000000000000001564 146.0
WLSH2_k127_857038_7 addiction module killer protein - - - 0.000000000000000000000000000000000000135 143.0
WLSH2_k127_8602615_0 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 436.0
WLSH2_k127_8602615_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 327.0
WLSH2_k127_8602615_2 Protein of unknown function (DUF2937) - - - 0.000000000000000000000000000000000000000000000000000000000000005791 228.0
WLSH2_k127_8659549_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 8.08e-304 942.0
WLSH2_k127_8659549_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 573.0
WLSH2_k127_8659549_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 345.0
WLSH2_k127_8659549_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 336.0
WLSH2_k127_8659549_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000002936 126.0
WLSH2_k127_8735307_0 surface antigen - - - 7.614e-252 792.0
WLSH2_k127_8737034_0 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 557.0
WLSH2_k127_8737034_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 507.0
WLSH2_k127_8737034_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000152 164.0
WLSH2_k127_8737034_3 TIGRFAM YgiT-type zinc finger domain - - - 0.000000000000000000000000000000000531 133.0
WLSH2_k127_8737034_4 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.000000000000000000000006246 107.0
WLSH2_k127_8742523_0 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 605.0
WLSH2_k127_8742523_1 Phosphoglycerate mutase family K08296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003683 247.0
WLSH2_k127_8742523_2 - - - - 0.000000000000000000000000003559 118.0
WLSH2_k127_8760072_0 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 4.422e-205 642.0
WLSH2_k127_8760072_1 ABC transporter K06020 - 3.6.3.25 1.54e-197 621.0
WLSH2_k127_8760072_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 586.0
WLSH2_k127_8760072_3 formate dehydrogenase, beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 535.0
WLSH2_k127_8760072_4 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000001303 82.0
WLSH2_k127_8760072_5 - - - - 0.0003014 47.0
WLSH2_k127_8780278_0 Outer membrane protein beta-barrel family K02014 - - 7.501e-254 801.0
WLSH2_k127_8780278_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 357.0
WLSH2_k127_8780278_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000162 257.0
WLSH2_k127_8780278_3 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000005273 166.0
WLSH2_k127_8786647_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 9.243e-212 662.0
WLSH2_k127_8786647_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 533.0
WLSH2_k127_8786647_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 526.0
WLSH2_k127_8786647_3 Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids K01995 - - 0.0000000000000000000000000000000000000000000001248 173.0
WLSH2_k127_880968_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 512.0
WLSH2_k127_880968_1 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000009238 147.0
WLSH2_k127_8811788_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 1.31e-238 743.0
WLSH2_k127_8811788_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
WLSH2_k127_8814762_0 Histidine kinase K20975 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002725 306.0
WLSH2_k127_8814762_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000005792 172.0
WLSH2_k127_8814762_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000000005791 139.0
WLSH2_k127_8814762_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000000000000000000008185 129.0
WLSH2_k127_8814762_4 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000009827 111.0
WLSH2_k127_8892268_0 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 9.525e-194 619.0
WLSH2_k127_8892268_1 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 471.0
WLSH2_k127_8892268_2 PLD-like domain K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 285.0
WLSH2_k127_8892268_3 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000001341 198.0
WLSH2_k127_8892268_4 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000008011 109.0
WLSH2_k127_8908923_0 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 5.557e-221 689.0
WLSH2_k127_8908923_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.398e-220 687.0
WLSH2_k127_8908923_10 ABC transporter transmembrane region K06147 - - 0.00001975 47.0
WLSH2_k127_8908923_2 NIF3 (NGG1p interacting factor 3) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 431.0
WLSH2_k127_8908923_3 Sigma-70 factor, region 1.2 K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 428.0
WLSH2_k127_8908923_4 Glutathione S-transferase, C-terminal domain K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 394.0
WLSH2_k127_8908923_5 Rieske [2Fe-2S] domain K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 292.0
WLSH2_k127_8908923_6 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000356 262.0
WLSH2_k127_8908923_7 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000000000000000000000001227 220.0
WLSH2_k127_8908923_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000427 105.0
WLSH2_k127_8908923_9 HIT domain K02503 - - 0.00000000000000000000001525 99.0
WLSH2_k127_8917523_0 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000691 118.0
WLSH2_k127_8968289_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 528.0
WLSH2_k127_8968289_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000007963 183.0
WLSH2_k127_8968289_2 Transposase IS116/IS110/IS902 family - - - 0.00000000000002176 73.0
WLSH2_k127_8968289_3 - - - - 0.0000000165 59.0
WLSH2_k127_8968289_4 - - - - 0.0007783 46.0
WLSH2_k127_9030006_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1305.0
WLSH2_k127_9030006_1 Malate:quinone oxidoreductase (Mqo) K00116 - 1.1.5.4 3.297e-226 707.0
WLSH2_k127_9113361_0 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 447.0
WLSH2_k127_9113361_1 Ligated ion channel L-glutamate- and glycine-binding site K02030,K10036 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 391.0
WLSH2_k127_9113361_2 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 316.0
WLSH2_k127_9113361_3 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000002583 135.0
WLSH2_k127_9138204_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 555.0
WLSH2_k127_9138204_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 304.0
WLSH2_k127_9138204_2 Glutathione peroxidase - - - 0.00000000004059 63.0
WLSH2_k127_9144209_0 PFAM aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 529.0
WLSH2_k127_9144209_1 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 254.0
WLSH2_k127_9144209_2 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000002814 88.0
WLSH2_k127_9181110_0 TonB dependent receptor K02014 - - 2.27e-198 640.0
WLSH2_k127_9181110_1 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 460.0
WLSH2_k127_9181110_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000007696 220.0
WLSH2_k127_9181110_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000186 222.0
WLSH2_k127_9181110_4 response regulator K13041 - - 0.00000000000000000000000000000000000000000000000000001486 196.0
WLSH2_k127_9181110_5 ABC transporter substrate binding protein - - - 0.0000000000000000000006245 104.0
WLSH2_k127_9181110_6 - - - - 0.0000000000002407 79.0
WLSH2_k127_9200910_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 349.0
WLSH2_k127_9200910_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000117 236.0
WLSH2_k127_9200910_2 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000000000000000001514 189.0
WLSH2_k127_9200910_3 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000001576 183.0
WLSH2_k127_9200910_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000002 52.0
WLSH2_k127_9202496_0 ABC transporter transmembrane region K06147 - - 1.579e-318 984.0
WLSH2_k127_9202496_1 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 470.0
WLSH2_k127_9202496_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 392.0
WLSH2_k127_9202496_3 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003094 252.0
WLSH2_k127_9202496_4 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
WLSH2_k127_9202496_5 Protein of unknown function (DUF1778) - - - 0.000000000000000000000000000000005425 129.0
WLSH2_k127_9202572_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.451e-265 819.0
WLSH2_k127_9202572_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 8.802e-260 804.0
WLSH2_k127_9202572_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 445.0
WLSH2_k127_9202572_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 439.0
WLSH2_k127_9202572_4 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 389.0
WLSH2_k127_9202572_5 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001922 270.0
WLSH2_k127_9202572_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000109 234.0
WLSH2_k127_9202572_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000002875 173.0
WLSH2_k127_9202572_8 Cellulose binding domain - - - 0.000000000000155 83.0
WLSH2_k127_9207879_0 PFAM DEAD DEAH box helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 600.0
WLSH2_k127_9207879_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 328.0
WLSH2_k127_9207879_2 TIR domain - - - 0.00000000000000000000000000000000000000000000000005354 189.0
WLSH2_k127_9207879_3 Plasmid stabilization system K19092 - - 0.0000000000000000000000000000000000000000000001279 171.0
WLSH2_k127_9207879_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000002069 147.0
WLSH2_k127_9207879_5 Malate:quinone oxidoreductase (Mqo) K00116 - 1.1.5.4 0.00000000000000000000000000004078 117.0
WLSH2_k127_9207879_6 Protein of unknown function (DUF433) - - - 0.0000000000000000000005189 104.0
WLSH2_k127_9207879_7 nucleoside 2-deoxyribosyltransferase - - - 0.0000001625 62.0
WLSH2_k127_9228454_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 2.524e-222 696.0
WLSH2_k127_9228454_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.183e-216 676.0
WLSH2_k127_9228454_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 560.0
WLSH2_k127_9228454_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000016 86.0
WLSH2_k127_924152_0 PFAM cobalamin synthesis protein P47K K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 503.0
WLSH2_k127_924152_1 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 407.0
WLSH2_k127_924152_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.000000000000000000000000000000000000103 147.0
WLSH2_k127_924152_3 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.000000000000000000000000000485 118.0
WLSH2_k127_924421_0 PFAM AICARFT IMPCHase bienzyme formylation region K00602 - 2.1.2.3,3.5.4.10 7.434e-290 893.0
WLSH2_k127_924421_1 Bacterial regulatory protein, Fis family K03557 - - 0.0000000000000000000000000000000005074 130.0
WLSH2_k127_9246583_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 554.0
WLSH2_k127_9246583_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 488.0
WLSH2_k127_9246583_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000009574 124.0
WLSH2_k127_9246583_11 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.00000000000000000004941 90.0
WLSH2_k127_9246583_12 - - - - 0.000000000002489 71.0
WLSH2_k127_9246583_13 - - - - 0.000000006949 61.0
WLSH2_k127_9246583_14 PFAM Uncharacterised protein family UPF0150 - - - 0.0005555 44.0
WLSH2_k127_9246583_2 Glycosyltransferase family 28 N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009602 331.0
WLSH2_k127_9246583_3 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 318.0
WLSH2_k127_9246583_4 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 299.0
WLSH2_k127_9246583_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 288.0
WLSH2_k127_9246583_6 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 295.0
WLSH2_k127_9246583_7 PFAM Peptidase S24 S26A S26B, conserved region - - - 0.0000000000000000000000000000000000000000000000000000004236 197.0
WLSH2_k127_9246583_8 Transcriptional regulator - - - 0.000000000000000000000000000000000002363 139.0
WLSH2_k127_9246583_9 - - - - 0.000000000000000000000000000000005689 129.0
WLSH2_k127_9251999_1 - - - - 0.00000000000000000000000000000000000000000000006379 181.0
WLSH2_k127_9260623_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1335.0
WLSH2_k127_9260623_1 Glycosyl hydrolase family 57 - - - 1.318e-308 952.0
WLSH2_k127_9260623_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.13e-248 768.0
WLSH2_k127_9260623_3 Starch synthase catalytic domain K00703 - 2.4.1.21 3.062e-242 755.0
WLSH2_k127_9260623_4 Belongs to the GPI family K01810 - 5.3.1.9 1.612e-230 725.0
WLSH2_k127_9260623_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 4.994e-212 661.0
WLSH2_k127_9260623_6 PFAM ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000452 218.0
WLSH2_k127_927500_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000002045 207.0
WLSH2_k127_927500_1 protein conserved in bacteria - - - 0.00000000000001042 80.0
WLSH2_k127_9326174_0 type II secretion system protein E K02454,K02652,K12276 - - 2.464e-206 652.0
WLSH2_k127_9326174_1 translation initiation factor activity K08086 - - 0.00000000000000016 90.0
WLSH2_k127_9408136_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 476.0
WLSH2_k127_9408136_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000001152 243.0
WLSH2_k127_9408136_2 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000000000000007851 199.0
WLSH2_k127_9408136_3 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000000000000007353 187.0
WLSH2_k127_9408136_4 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000004046 95.0
WLSH2_k127_9421517_0 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 3.945e-217 678.0
WLSH2_k127_9421517_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
WLSH2_k127_9421517_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 317.0
WLSH2_k127_9421517_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 305.0
WLSH2_k127_9421517_4 Bacterial dnaA protein K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 301.0
WLSH2_k127_9421517_5 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007466 274.0
WLSH2_k127_9421517_6 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000006883 223.0
WLSH2_k127_9464799_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 441.0
WLSH2_k127_9464799_1 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 312.0
WLSH2_k127_9464799_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000583 250.0
WLSH2_k127_9464799_3 - - - - 0.00000000000000000000000000000000000000000002182 164.0
WLSH2_k127_9464799_4 TIGRFAM addiction module toxin, RelE StbE family K19092 - - 0.00000000000000000000000000000000000000015 151.0
WLSH2_k127_9464799_5 Protein of unknown function (DUF2288) - - - 0.0000000000000000000000000000007457 129.0
WLSH2_k127_9464799_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000009311 117.0
WLSH2_k127_9464799_7 - - - - 0.000000000000000000000002702 106.0
WLSH2_k127_9464799_8 Plasmid stabilization system - - - 0.000000000000000001812 89.0
WLSH2_k127_9464799_9 addiction module component - - - 0.00000948 50.0
WLSH2_k127_9477682_0 cofactor biosynthesis protein NifB K02585 - - 3.131e-296 914.0
WLSH2_k127_9477682_1 PFAM DEAD DEAH box helicase domain protein K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 2.379e-269 833.0
WLSH2_k127_9477682_2 Class III cytochrome C family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 409.0
WLSH2_k127_9477682_3 purine ribonucleoside salvage K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 277.0
WLSH2_k127_9477682_4 - - - - 0.0000000000000000000000000000000000000000000000000000004136 199.0
WLSH2_k127_9477682_5 Nitrogenase component 1 type Oxidoreductase K02592 - - 0.0002962 43.0
WLSH2_k127_9495840_0 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 497.0
WLSH2_k127_9495840_1 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000001919 207.0
WLSH2_k127_9495840_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000007713 169.0
WLSH2_k127_9531972_0 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 423.0
WLSH2_k127_9531972_1 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 286.0
WLSH2_k127_9531972_10 PFAM Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000222 70.0
WLSH2_k127_9531972_2 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006837 255.0
WLSH2_k127_9531972_3 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000002597 261.0
WLSH2_k127_9531972_4 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000002799 193.0
WLSH2_k127_9531972_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000000000000000000006571 183.0
WLSH2_k127_9531972_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000001988 146.0
WLSH2_k127_9531972_7 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.00000000000000000000000000000009829 138.0
WLSH2_k127_9531972_8 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000001766 129.0
WLSH2_k127_9531972_9 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000003297 123.0
WLSH2_k127_9537135_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.757e-287 890.0
WLSH2_k127_9537135_1 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 513.0
WLSH2_k127_9537135_2 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 493.0
WLSH2_k127_9537135_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000000000001959 125.0
WLSH2_k127_9540884_0 - - - - 1.258e-302 944.0
WLSH2_k127_9540884_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.11e-291 900.0
WLSH2_k127_9540884_10 FMN_bind - - - 0.0000000000000000000000000000000000000000001414 167.0
WLSH2_k127_9540884_11 Thioredoxin domain - - - 0.0000000000000000000000000000000003342 133.0
WLSH2_k127_9540884_13 diguanylate cyclase - - - 0.000000000000001359 78.0
WLSH2_k127_9540884_14 - - - - 0.000000000000006002 81.0
WLSH2_k127_9540884_15 Nucleotidyltransferase domain - - - 0.00000000000001932 78.0
WLSH2_k127_9540884_2 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 564.0
WLSH2_k127_9540884_3 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 433.0
WLSH2_k127_9540884_4 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 388.0
WLSH2_k127_9540884_5 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009228 259.0
WLSH2_k127_9540884_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000003787 237.0
WLSH2_k127_9540884_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000005957 211.0
WLSH2_k127_9540884_8 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000004026 207.0
WLSH2_k127_9540884_9 - - - - 0.0000000000000000000000000000000000000000000000000000002406 201.0
WLSH2_k127_9544867_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.835e-268 829.0
WLSH2_k127_9544867_1 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 490.0
WLSH2_k127_9544867_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000008206 117.0
WLSH2_k127_9544867_3 response to toxic substance K16347,K16348 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00005441 46.0
WLSH2_k127_9552584_0 TIGRFAM fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 4.519e-202 631.0
WLSH2_k127_9552584_1 Di-haem cytochrome c peroxidase K00428 GO:0000302,GO:0003674,GO:0003824,GO:0004130,GO:0004601,GO:0005488,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009061,GO:0009636,GO:0009987,GO:0010035,GO:0015980,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0042221,GO:0042493,GO:0042542,GO:0042743,GO:0044237,GO:0045333,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 364.0
WLSH2_k127_9552584_2 PAC sensor-containing diguanylate cyclase phosphodiesterase - - - 0.000000000821 62.0
WLSH2_k127_9552760_0 HI0933-like protein K07007 - - 5.262e-206 649.0
WLSH2_k127_9552760_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 290.0
WLSH2_k127_9552760_2 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003788 272.0
WLSH2_k127_9552760_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000002305 232.0
WLSH2_k127_9552760_4 TIGRFAM ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000000000000000000000000000001613 207.0
WLSH2_k127_9552760_5 Iron-sulphur cluster assembly - - - 0.00000000000000000000000001531 115.0
WLSH2_k127_9552760_6 Hemerythrin HHE cation binding domain - - - 0.00000000000000006248 82.0
WLSH2_k127_9562363_0 general secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 392.0
WLSH2_k127_9562363_1 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000007916 219.0
WLSH2_k127_9562363_2 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000008141 217.0
WLSH2_k127_9562363_3 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000009111 151.0
WLSH2_k127_9562363_4 general secretion pathway protein K02246,K02247,K02456,K02457,K02458,K10924,K12285 - - 0.0000000000000000000000000000000000002485 149.0
WLSH2_k127_9562363_5 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.00000000000000000000000000000001198 129.0
WLSH2_k127_9575581_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 391.0
WLSH2_k127_9575581_1 NMT1/THI5 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 358.0
WLSH2_k127_9575581_2 DSBA-like thioredoxin domain K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 267.0
WLSH2_k127_9575581_3 Sporulation related domain - - - 0.0000000000000000000000000000000000000000007371 163.0
WLSH2_k127_9575581_4 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000004176 154.0
WLSH2_k127_9578976_0 Histidine kinase - - - 2.283e-206 673.0
WLSH2_k127_9578976_1 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 359.0
WLSH2_k127_9578976_2 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004112 269.0
WLSH2_k127_9578976_3 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002797 217.0
WLSH2_k127_9578976_4 histidine kinase A domain protein - - - 0.000006437 49.0
WLSH2_k127_9583487_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 303.0
WLSH2_k127_9583487_1 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000000000000000000000000004167 239.0
WLSH2_k127_9583487_2 TPR repeat - - - 0.00000000000000000000001601 106.0
WLSH2_k127_9583487_3 translation initiation factor activity K08086 - - 0.00000000000002309 81.0
WLSH2_k127_9618653_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0 1448.0
WLSH2_k127_9618653_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.167e-291 899.0
WLSH2_k127_9618653_10 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000002297 205.0
WLSH2_k127_9618653_11 - - - - 0.0000000000000000000000000000000000000000000000000001426 188.0
WLSH2_k127_9618653_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000552 173.0
WLSH2_k127_9618653_13 PFAM PilT protein domain protein - - - 0.00000000000000000000000000000000000000000004496 163.0
WLSH2_k127_9618653_14 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000000000000000127 159.0
WLSH2_k127_9618653_15 Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO K21694 - - 0.000000000000000000000000000002555 122.0
WLSH2_k127_9618653_16 TIGRFAM cytochrome c oxidase accessory protein CcoG - - - 0.0000000000000000000000002856 105.0
WLSH2_k127_9618653_17 PFAM cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000000000000001402 100.0
WLSH2_k127_9618653_18 positive regulation of growth - - - 0.000946 44.0
WLSH2_k127_9618653_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 9.83e-257 796.0
WLSH2_k127_9618653_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.011e-242 754.0
WLSH2_k127_9618653_4 Nitronate monooxygenase K00459 - 1.13.12.16 1.002e-239 745.0
WLSH2_k127_9618653_5 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 542.0
WLSH2_k127_9618653_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 347.0
WLSH2_k127_9618653_7 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 316.0
WLSH2_k127_9618653_8 FixH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 285.0
WLSH2_k127_9618653_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002744 243.0
WLSH2_k127_9626275_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 8.799e-206 642.0
WLSH2_k127_9626275_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 326.0
WLSH2_k127_9626275_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 304.0
WLSH2_k127_9626275_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004931 241.0
WLSH2_k127_9626275_4 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000006527 180.0
WLSH2_k127_9628803_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.31e-201 629.0
WLSH2_k127_9628803_1 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000000000006391 151.0
WLSH2_k127_9632450_0 Large extracellular alpha-helical protein K06894 - - 0.0 1568.0
WLSH2_k127_9632450_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 997.0
WLSH2_k127_9632450_2 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.888e-253 805.0
WLSH2_k127_9632450_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000004103 162.0
WLSH2_k127_9632450_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000001105 51.0
WLSH2_k127_9640701_0 Peptidase M16 inactive domain K07263 - - 1.722e-210 661.0
WLSH2_k127_9640701_1 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 307.0
WLSH2_k127_9640701_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002336 273.0
WLSH2_k127_9640701_3 PFAM Peptidase M16 K07263 - - 0.000000000006262 66.0
WLSH2_k127_9645957_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 497.0
WLSH2_k127_9645957_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 303.0
WLSH2_k127_9645957_2 - - - - 0.0007 43.0
WLSH2_k127_9649754_0 Participates in both transcription termination and antitermination K02600 - - 5.322e-288 887.0
WLSH2_k127_9649754_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.727e-227 716.0
WLSH2_k127_9649754_2 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009658 511.0
WLSH2_k127_9649754_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 371.0
WLSH2_k127_9649754_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005074 260.0
WLSH2_k127_9649754_5 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004242 255.0
WLSH2_k127_965216_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 7.369e-268 831.0
WLSH2_k127_965216_1 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
WLSH2_k127_9664972_0 Adenylate cyclase K01768 - 4.6.1.1 4.163e-216 686.0
WLSH2_k127_9664972_1 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 383.0
WLSH2_k127_9664972_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 381.0
WLSH2_k127_9664972_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 294.0
WLSH2_k127_9668020_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 545.0
WLSH2_k127_9668020_1 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 323.0
WLSH2_k127_9668020_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 265.0
WLSH2_k127_9668020_3 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000004088 199.0
WLSH2_k127_9676644_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 323.0
WLSH2_k127_9676644_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000002428 214.0
WLSH2_k127_9733525_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.168e-295 910.0
WLSH2_k127_9733525_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 343.0
WLSH2_k127_9734462_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 6.443e-314 973.0
WLSH2_k127_9734462_1 fibronectin type III domain protein K06882 - - 6.495e-300 940.0
WLSH2_k127_9734462_2 Resolvase - - - 0.0000004035 52.0
WLSH2_k127_976923_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.249e-312 959.0
WLSH2_k127_976923_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.929e-206 643.0
WLSH2_k127_976923_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 516.0
WLSH2_k127_976923_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 508.0
WLSH2_k127_976923_4 ParB-like nuclease domain K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 499.0
WLSH2_k127_976923_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 289.0
WLSH2_k127_976923_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001522 278.0
WLSH2_k127_976923_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000396 143.0
WLSH2_k127_976923_8 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000007975 133.0
WLSH2_k127_9982367_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1156.0
WLSH2_k127_9982367_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 3.926e-203 635.0
WLSH2_k127_9982367_2 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 344.0
WLSH2_k127_9982367_3 Chitinase class I K03791 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004278 275.0
WLSH2_k127_9982367_4 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000000000000008069 233.0
WLSH2_k127_9982367_5 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000000000000000000000000001932 182.0
WLSH2_k127_9982367_6 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000001072 172.0
WLSH2_k127_9982367_7 PFAM guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.00000000000000000000000000000000000000001156 156.0
WLSH2_k127_9982367_8 Putative regulatory protein - - - 0.000000000000000000000000009148 111.0