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Overview

ID MAG04214
Name WLSH2_bin.44
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota_B
Class Binatia
Order DP-6
Family
Genus
Species
Assembly information
Completeness (%) 62.46
Contamination (%) 1.47
GC content (%) 62.0
N50 (bp) 14,199
Genome size (bp) 3,168,561

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2657

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_1001639_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 382.0
WLSH2_k127_1001639_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 367.0
WLSH2_k127_1001639_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 364.0
WLSH2_k127_1001639_3 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 345.0
WLSH2_k127_1001639_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 342.0
WLSH2_k127_1001639_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 319.0
WLSH2_k127_1001639_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000009507 173.0
WLSH2_k127_1001639_7 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000171 156.0
WLSH2_k127_1003926_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 508.0
WLSH2_k127_1003926_1 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 338.0
WLSH2_k127_1003926_10 membrane - - - 0.00000000000000000005984 95.0
WLSH2_k127_1003926_11 Integrase - - - 0.0000002048 57.0
WLSH2_k127_1003926_12 transferase activity, transferring glycosyl groups - - - 0.0000003863 57.0
WLSH2_k127_1003926_2 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009118 273.0
WLSH2_k127_1003926_3 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000006399 198.0
WLSH2_k127_1003926_4 FMN binding - - - 0.000000000000000000000000000000000000000000000000000002153 195.0
WLSH2_k127_1003926_5 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000003682 196.0
WLSH2_k127_1003926_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000004273 156.0
WLSH2_k127_1003926_7 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000001281 147.0
WLSH2_k127_1003926_8 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000004715 148.0
WLSH2_k127_1003926_9 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000000000000633 144.0
WLSH2_k127_10043416_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001527 277.0
WLSH2_k127_10043416_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003594 286.0
WLSH2_k127_10043416_2 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000343 267.0
WLSH2_k127_10043416_3 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000000000001919 236.0
WLSH2_k127_10043416_4 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000002903 243.0
WLSH2_k127_10043416_5 COG1121 ABC-type Mn Zn transport systems ATPase component K11607,K11710 - - 0.0000000000000000000000000000000000000000000000000000001512 203.0
WLSH2_k127_10043416_6 Cysteine-rich domain K00113 - 1.1.5.3 0.00000000000000000000000000000000000000352 157.0
WLSH2_k127_10043416_7 ABC-type Mn2 Zn2 transport systems permease components - - - 0.00000000000000000000000000002592 127.0
WLSH2_k127_10043416_8 Tfp pilus assembly protein FimV - - - 0.00000000000001557 87.0
WLSH2_k127_10043416_9 Pectic acid lyase - - - 0.00000000009138 74.0
WLSH2_k127_10052568_0 DEAD-like helicases superfamily - - - 1.258e-286 902.0
WLSH2_k127_10052568_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000015 165.0
WLSH2_k127_10052568_2 nucleic acid-binding protein, contains PIN domain K07065 - - 0.000000000000000000000000000000000000001564 154.0
WLSH2_k127_10052568_3 PIN domain - - - 0.0000000000000000000000000000000001265 138.0
WLSH2_k127_10052568_4 Protein of unknown function (DUF433) - - - 0.0000000000000007364 80.0
WLSH2_k127_10052568_5 nuclease activity K06218 - - 0.0000000000000007969 80.0
WLSH2_k127_10052568_6 - - - - 0.0000007219 55.0
WLSH2_k127_10106117_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1176.0
WLSH2_k127_10106117_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.573e-209 662.0
WLSH2_k127_10106117_10 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000001769 206.0
WLSH2_k127_10106117_11 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000008162 134.0
WLSH2_k127_10106117_12 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000003709 134.0
WLSH2_k127_10106117_13 PFAM response regulator receiver K02488,K02658 - 2.7.7.65 0.000000000000000000000000000004977 126.0
WLSH2_k127_10106117_14 HDOD domain - - - 0.00000000000000000001166 104.0
WLSH2_k127_10106117_15 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000001688 70.0
WLSH2_k127_10106117_16 Flavodoxin - - - 0.0002545 51.0
WLSH2_k127_10106117_2 Catalytic activity. It is involved in the biological process described with trehalose biosynthetic process K01087,K16055 GO:0003674,GO:0003824,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005991,GO:0005992,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0033554,GO:0034637,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044424,GO:0044464,GO:0046351,GO:0050896,GO:0051716,GO:0070413,GO:0071704,GO:1901576 2.4.1.15,3.1.3.12 2.893e-197 644.0
WLSH2_k127_10106117_3 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 444.0
WLSH2_k127_10106117_4 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 398.0
WLSH2_k127_10106117_5 Peptidase M20 K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 368.0
WLSH2_k127_10106117_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 357.0
WLSH2_k127_10106117_7 Alkylmercury lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 303.0
WLSH2_k127_10106117_8 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002557 280.0
WLSH2_k127_10106117_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001194 278.0
WLSH2_k127_1013169_0 GHKL domain - - - 0.00000000000000000000000000000000000000000000000007906 201.0
WLSH2_k127_1013169_1 Belongs to the GSP D family K02280 - - 0.0000000000000000000000000000000000000001765 172.0
WLSH2_k127_1013169_2 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000001612 114.0
WLSH2_k127_1013169_3 TadE-like protein - - - 0.000000000001677 77.0
WLSH2_k127_1013169_4 sequence-specific DNA binding K07726 - - 0.00000000002976 66.0
WLSH2_k127_1013169_5 TadE-like protein - - - 0.000000002953 64.0
WLSH2_k127_10155814_0 PFAM Glycoside hydrolase 15-related - - - 5e-324 1023.0
WLSH2_k127_10155814_1 Glycosyl transferase family 21 K03669 - - 1.81e-232 750.0
WLSH2_k127_10155814_10 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000002057 228.0
WLSH2_k127_10155814_11 Belongs to the 'phage' integrase family K03733 - - 0.00000000000000000007532 93.0
WLSH2_k127_10155814_12 Protein of unknown function (DUF2283) - - - 0.000000000000000001918 85.0
WLSH2_k127_10155814_13 - - - - 0.00000000004185 66.0
WLSH2_k127_10155814_14 - - - - 0.0000000009091 61.0
WLSH2_k127_10155814_15 - - - - 0.00000397 49.0
WLSH2_k127_10155814_16 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00001213 51.0
WLSH2_k127_10155814_2 periplasmic glucan biosynthesis protein K03670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 537.0
WLSH2_k127_10155814_3 ABC transporter substrate-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 474.0
WLSH2_k127_10155814_4 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 423.0
WLSH2_k127_10155814_5 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 407.0
WLSH2_k127_10155814_6 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 386.0
WLSH2_k127_10155814_7 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 342.0
WLSH2_k127_10155814_8 COG0744 Membrane carboxypeptidase (penicillin-binding protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 319.0
WLSH2_k127_10155814_9 carbohydrate binding K00702 - 2.4.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 320.0
WLSH2_k127_10193706_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1142.0
WLSH2_k127_10193706_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 315.0
WLSH2_k127_10193706_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 319.0
WLSH2_k127_10193706_3 transposition K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002213 281.0
WLSH2_k127_10193706_4 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 285.0
WLSH2_k127_10193706_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000004777 141.0
WLSH2_k127_10193706_6 CAAX protease self-immunity - - - 0.000000000000000000001474 108.0
WLSH2_k127_10193706_7 Thrombospondin type 3 repeat - - - 0.000000007954 69.0
WLSH2_k127_10193706_8 Belongs to the peptidase M10A family - - - 0.00000002409 67.0
WLSH2_k127_10232611_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.416e-195 625.0
WLSH2_k127_10232611_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 591.0
WLSH2_k127_10232611_10 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000000000000001782 202.0
WLSH2_k127_10232611_11 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000004974 199.0
WLSH2_k127_10232611_12 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000001924 169.0
WLSH2_k127_10232611_13 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000001609 175.0
WLSH2_k127_10232611_14 Thioesterase superfamily - - - 0.0000000000000000003454 98.0
WLSH2_k127_10232611_15 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000001404 72.0
WLSH2_k127_10232611_2 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 512.0
WLSH2_k127_10232611_3 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 389.0
WLSH2_k127_10232611_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 368.0
WLSH2_k127_10232611_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 365.0
WLSH2_k127_10232611_6 associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 344.0
WLSH2_k127_10232611_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 323.0
WLSH2_k127_10232611_8 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 293.0
WLSH2_k127_10232611_9 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000477 231.0
WLSH2_k127_10310993_0 CoA-transferase family III K07544 - 2.8.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 573.0
WLSH2_k127_10310993_1 Enoyl-CoA hydratase/isomerase K07546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 357.0
WLSH2_k127_10310993_2 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000155 278.0
WLSH2_k127_10310993_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000003309 168.0
WLSH2_k127_10310993_4 Putative beta-lactamase-inhibitor-like, PepSY-like - - - 0.00000000000000000004452 96.0
WLSH2_k127_10310993_5 PHB/PHA accumulation regulator DNA-binding domain - - - 0.000000000000000002031 91.0
WLSH2_k127_10310993_6 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000001306 69.0
WLSH2_k127_1031258_0 PFAM 2-nitropropane dioxygenase NPD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 556.0
WLSH2_k127_1031258_1 Fe-S protein K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003814 273.0
WLSH2_k127_1031258_10 Bacterial regulatory proteins, tetR family - - - 0.00000000001743 69.0
WLSH2_k127_1031258_11 Diguanylate cyclase - - - 0.0000000007035 69.0
WLSH2_k127_1031258_12 Bacterial regulatory proteins, tetR family K09017 - - 0.000000001336 62.0
WLSH2_k127_1031258_13 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000805 65.0
WLSH2_k127_1031258_14 PIN domain - - - 0.000004765 56.0
WLSH2_k127_1031258_16 positive regulation of growth - - - 0.0001958 47.0
WLSH2_k127_1031258_17 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0002263 49.0
WLSH2_k127_1031258_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000003899 201.0
WLSH2_k127_1031258_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000003186 171.0
WLSH2_k127_1031258_4 - K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000004225 139.0
WLSH2_k127_1031258_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000000000000000007299 121.0
WLSH2_k127_1031258_6 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000006385 128.0
WLSH2_k127_1031258_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.00000000000000000000000005552 111.0
WLSH2_k127_1031258_8 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000001608 107.0
WLSH2_k127_1031258_9 GatB Yqey domain protein K09117 - - 0.000000000000000000000006086 103.0
WLSH2_k127_10317233_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 9.224e-235 758.0
WLSH2_k127_10317233_1 4Fe-4S dicluster domain K17048,K17051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 471.0
WLSH2_k127_10317233_10 Bacterial regulatory proteins, tetR family K09017 - - 0.000000000000002338 85.0
WLSH2_k127_10317233_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 314.0
WLSH2_k127_10317233_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000004091 208.0
WLSH2_k127_10317233_4 nitrate reductase molybdenum cofactor assembly chaperone K17052 - - 0.000000000000000000000000000000000000000000000000001151 193.0
WLSH2_k127_10317233_5 HDOD domain - - - 0.00000000000000000000000000000000000000000000003975 182.0
WLSH2_k127_10317233_6 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000194 163.0
WLSH2_k127_10317233_7 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000001271 138.0
WLSH2_k127_10317233_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000003843 114.0
WLSH2_k127_10317233_9 cyclic nucleotide-binding K01420,K10914 - - 0.000000000000000000000003324 112.0
WLSH2_k127_10360603_0 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 428.0
WLSH2_k127_10360603_1 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 330.0
WLSH2_k127_10360603_10 nuclease activity K18828 - - 0.000001477 56.0
WLSH2_k127_10360603_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000014 294.0
WLSH2_k127_10360603_3 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001038 282.0
WLSH2_k127_10360603_4 - K06921 - - 0.00000000000000000000000000000000000000000000000000000004411 211.0
WLSH2_k127_10360603_5 periplasmic glucan biosynthesis protein K03670 - - 0.00000000000000000000000000000000000000000000000000003992 192.0
WLSH2_k127_10360603_6 - - - - 0.0000000000000000000000002619 121.0
WLSH2_k127_10360603_7 Nucleotidyltransferase domain - - - 0.00000000000002722 80.0
WLSH2_k127_10360603_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000002631 79.0
WLSH2_k127_10360603_9 positive regulation of growth K18829 - - 0.00000004266 58.0
WLSH2_k127_10409586_0 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007779 299.0
WLSH2_k127_10409586_1 Sh3 type 3 domain protein - - - 0.0000000000000000000002054 113.0
WLSH2_k127_10409586_2 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000001299 111.0
WLSH2_k127_10409586_3 Thiol disulfide interchange protein dsbA - - - 0.000000007269 64.0
WLSH2_k127_10409586_4 Periplasmic protein thiol disulfide oxidoreductase, DsbE subfamily - - - 0.00000001268 68.0
WLSH2_k127_10409586_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000005639 66.0
WLSH2_k127_10409586_6 Bacterial membrane protein, YfhO - - - 0.0000002318 64.0
WLSH2_k127_10409586_7 Thioesterase-like superfamily - - - 0.0000128 56.0
WLSH2_k127_10409586_8 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00005046 57.0
WLSH2_k127_10426047_0 Heat shock protein 70 family - - - 1.088e-264 827.0
WLSH2_k127_10426047_1 Belongs to the heat shock protein 70 family - - - 1.059e-203 646.0
WLSH2_k127_10426047_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 293.0
WLSH2_k127_10426047_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001267 284.0
WLSH2_k127_10426047_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008773 284.0
WLSH2_k127_10426047_13 3-oxosteroid 1-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009603 257.0
WLSH2_k127_10426047_14 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000002978 235.0
WLSH2_k127_10426047_15 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000001751 239.0
WLSH2_k127_10426047_16 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000009313 229.0
WLSH2_k127_10426047_17 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000002987 207.0
WLSH2_k127_10426047_18 - - - - 0.0000000000000000000000000000000000000000000000000000008995 203.0
WLSH2_k127_10426047_19 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000248 194.0
WLSH2_k127_10426047_2 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 4.983e-195 619.0
WLSH2_k127_10426047_20 Domain of unknown function (DUF2760) - - - 0.000000000000000000000000000000000000000000000000009014 190.0
WLSH2_k127_10426047_21 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001117 197.0
WLSH2_k127_10426047_22 NUDIX domain - - - 0.0000000000000000000000000000000000000000000002346 173.0
WLSH2_k127_10426047_23 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family - - - 0.00000000000000000000000000000000000000000000848 170.0
WLSH2_k127_10426047_24 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000000009957 124.0
WLSH2_k127_10426047_25 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000003754 132.0
WLSH2_k127_10426047_26 - - - - 0.0000000000000000000000000007319 115.0
WLSH2_k127_10426047_27 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000001316 106.0
WLSH2_k127_10426047_28 Polymer-forming cytoskeletal - - - 0.00000000000000000001272 101.0
WLSH2_k127_10426047_29 Bacterial regulatory proteins, tetR family - - - 0.000000000000000004111 92.0
WLSH2_k127_10426047_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 576.0
WLSH2_k127_10426047_30 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000002068 67.0
WLSH2_k127_10426047_31 Mut7-C ubiquitin - - - 0.0000004161 60.0
WLSH2_k127_10426047_32 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000001851 52.0
WLSH2_k127_10426047_33 MazG-like family - - - 0.00003745 46.0
WLSH2_k127_10426047_34 Domain of unknown function (DUF4340) - - - 0.0003865 49.0
WLSH2_k127_10426047_4 lysine 2,3-aminomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 575.0
WLSH2_k127_10426047_5 FAD dependent oxidoreductase K16051 - 1.3.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 471.0
WLSH2_k127_10426047_6 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 434.0
WLSH2_k127_10426047_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 410.0
WLSH2_k127_10426047_8 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 374.0
WLSH2_k127_10426047_9 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 347.0
WLSH2_k127_10426430_0 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 464.0
WLSH2_k127_10426430_1 PFAM sigma-54 factor interaction domain-containing protein K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 432.0
WLSH2_k127_10426430_10 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000001512 86.0
WLSH2_k127_10426430_11 Glycosyltransferase Family 4 - - - 0.000000002629 63.0
WLSH2_k127_10426430_12 Transposase K20444 - - 0.00000001989 67.0
WLSH2_k127_10426430_13 Glycosyltransferase like family 2 - - - 0.00001025 54.0
WLSH2_k127_10426430_14 Methyltransferase domain - - - 0.00002784 57.0
WLSH2_k127_10426430_15 Tetratricopeptide repeat - - - 0.0007607 53.0
WLSH2_k127_10426430_16 flagellar motor switch protein FliG K02410 - - 0.0007843 43.0
WLSH2_k127_10426430_2 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 340.0
WLSH2_k127_10426430_3 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 343.0
WLSH2_k127_10426430_4 Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002411 259.0
WLSH2_k127_10426430_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000002949 221.0
WLSH2_k127_10426430_6 phosphorelay sensor kinase activity K07710,K10942 - 2.7.13.3 0.000000000000000000000000000000000000000000000713 178.0
WLSH2_k127_10426430_7 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000009622 160.0
WLSH2_k127_10426430_8 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000004329 144.0
WLSH2_k127_10426430_9 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000009861 91.0
WLSH2_k127_10432607_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 360.0
WLSH2_k127_10432607_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001231 289.0
WLSH2_k127_10432607_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000006839 220.0
WLSH2_k127_10432607_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000151 201.0
WLSH2_k127_10432607_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000001782 142.0
WLSH2_k127_10432607_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0030312,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000006762 142.0
WLSH2_k127_10456389_0 Protein of unknown function (DUF3604) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 594.0
WLSH2_k127_10456389_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 565.0
WLSH2_k127_10456389_10 Sulfotransferase domain - - - 0.0000000001549 65.0
WLSH2_k127_10456389_11 Helix-turn-helix domain - - - 0.00000002679 66.0
WLSH2_k127_10456389_12 diguanylate cyclase - - - 0.0000002636 57.0
WLSH2_k127_10456389_13 PIN domain - - - 0.0001219 51.0
WLSH2_k127_10456389_14 Cysteine-rich domain - - - 0.0002371 51.0
WLSH2_k127_10456389_2 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 511.0
WLSH2_k127_10456389_3 translation release factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001036 259.0
WLSH2_k127_10456389_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000448 247.0
WLSH2_k127_10456389_5 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000005688 239.0
WLSH2_k127_10456389_6 - - - - 0.00000000000000000000000000000000000000000000000000009025 194.0
WLSH2_k127_10456389_7 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000003282 137.0
WLSH2_k127_10456389_8 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000005232 106.0
WLSH2_k127_10456389_9 - - - - 0.000000000000007538 76.0
WLSH2_k127_10462179_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 4.828e-233 733.0
WLSH2_k127_10462179_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 624.0
WLSH2_k127_10462179_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 586.0
WLSH2_k127_10462179_3 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 470.0
WLSH2_k127_10462179_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 446.0
WLSH2_k127_10462179_5 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001239 250.0
WLSH2_k127_10462179_6 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000008456 132.0
WLSH2_k127_10485928_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.389e-206 649.0
WLSH2_k127_10485928_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 577.0
WLSH2_k127_10485928_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 466.0
WLSH2_k127_10485928_3 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 378.0
WLSH2_k127_10485928_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000001815 249.0
WLSH2_k127_10485928_5 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000003904 252.0
WLSH2_k127_10485928_6 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000000000000000000000000004414 224.0
WLSH2_k127_10485928_7 cyclic nucleotide binding K01420 - - 0.000000000000000000000000000000000000000000001257 174.0
WLSH2_k127_10485928_8 PFAM ATP-binding region, ATPase domain protein K07636,K07652 - 2.7.13.3 0.000000000002101 80.0
WLSH2_k127_10633039_0 PFAM Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 614.0
WLSH2_k127_10633039_1 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000712 198.0
WLSH2_k127_10633039_2 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.000000000000000000000000000000000000000000001307 167.0
WLSH2_k127_10633039_3 Polysaccharide export protein K01991,K20988 - - 0.00000000000000000000000000000000000000000001712 178.0
WLSH2_k127_10633039_4 Capsular exopolysaccharide family K16554,K16692 - - 0.0000000000000000000000000000000000000003649 160.0
WLSH2_k127_10633039_5 Protein of unknown function DUF86 - - - 0.00000000000000000000000764 107.0
WLSH2_k127_10633039_6 Nucleotidyltransferase domain - - - 0.000000000000000002031 93.0
WLSH2_k127_10633039_7 ATPase (AAA superfamily - - - 0.000000005786 59.0
WLSH2_k127_10757478_0 Valyl tRNA synthetase tRNA binding arm K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1083.0
WLSH2_k127_10757478_1 ABC transporter K02471 - - 2.87e-199 636.0
WLSH2_k127_10757478_2 Transglycosylase SLT domain K08307,K12204,K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 370.0
WLSH2_k127_10757478_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 325.0
WLSH2_k127_10757478_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278,K00767 - 1.4.3.16,2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008502 275.0
WLSH2_k127_10757478_5 Domain of unknown function (DUF4336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001113 240.0
WLSH2_k127_10757478_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000006679 226.0
WLSH2_k127_10757478_7 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000003382 231.0
WLSH2_k127_10757478_8 - - - - 0.0000000000003865 79.0
WLSH2_k127_10801331_0 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
WLSH2_k127_10801331_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000006288 198.0
WLSH2_k127_10801331_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000003189 142.0
WLSH2_k127_10801331_3 Bacterial regulatory proteins, tetR family - - - 0.0000000003495 62.0
WLSH2_k127_10801331_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0002876 48.0
WLSH2_k127_10801331_5 metalloendopeptidase activity K01315 - 3.4.21.7 0.0005395 53.0
WLSH2_k127_10816621_0 Sodium:sulfate symporter transmembrane region - - - 1.236e-206 659.0
WLSH2_k127_10816621_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 531.0
WLSH2_k127_10816621_10 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000007072 214.0
WLSH2_k127_10816621_11 PFAM Divergent AAA domain K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000001092 207.0
WLSH2_k127_10816621_12 methyltransferase K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000417 192.0
WLSH2_k127_10816621_13 Group II intron, maturase-specific domain - - - 0.00000000000000000000000000000000000000000000006669 175.0
WLSH2_k127_10816621_14 Transporter Component K07112 - - 0.00000000000000000000000000000000000000571 154.0
WLSH2_k127_10816621_15 transporter component K07112 - - 0.0000000000000000000000000000000000182 139.0
WLSH2_k127_10816621_17 Transposase zinc-binding domain - - - 0.000000001237 65.0
WLSH2_k127_10816621_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 388.0
WLSH2_k127_10816621_20 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000004655 54.0
WLSH2_k127_10816621_21 Integrase - - - 0.0003851 45.0
WLSH2_k127_10816621_3 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 327.0
WLSH2_k127_10816621_4 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 313.0
WLSH2_k127_10816621_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 304.0
WLSH2_k127_10816621_6 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 297.0
WLSH2_k127_10816621_7 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003913 300.0
WLSH2_k127_10816621_8 Electron transfer flavoprotein, beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004797 280.0
WLSH2_k127_10816621_9 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001335 256.0
WLSH2_k127_10832821_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 507.0
WLSH2_k127_10832821_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 381.0
WLSH2_k127_10832821_10 FAD linked oxidase domain protein - - - 0.0000000000000000001282 90.0
WLSH2_k127_10832821_11 - - - - 0.0000000004126 68.0
WLSH2_k127_10832821_12 Rubrerythrin - - - 0.000004213 55.0
WLSH2_k127_10832821_2 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 327.0
WLSH2_k127_10832821_3 ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002672 289.0
WLSH2_k127_10832821_4 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004479 267.0
WLSH2_k127_10832821_5 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000001424 205.0
WLSH2_k127_10832821_6 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000008932 155.0
WLSH2_k127_10832821_7 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000001208 153.0
WLSH2_k127_10832821_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000483 119.0
WLSH2_k127_10832821_9 Winged helix DNA-binding domain - - - 0.0000000000000000000002537 102.0
WLSH2_k127_10836442_0 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 371.0
WLSH2_k127_10836442_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 342.0
WLSH2_k127_10836442_11 PFAM Radical SAM domain protein - - - 0.00000000000000000001266 102.0
WLSH2_k127_10836442_12 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000001576 67.0
WLSH2_k127_10836442_13 Protein of unknown function (DUF1566) - - - 0.000006902 57.0
WLSH2_k127_10836442_14 Acetyltransferase (GNAT) domain - - - 0.0001126 49.0
WLSH2_k127_10836442_15 HNH endonuclease K07451,K07452 - - 0.000132 48.0
WLSH2_k127_10836442_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 329.0
WLSH2_k127_10836442_3 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000104 259.0
WLSH2_k127_10836442_4 glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000004368 234.0
WLSH2_k127_10836442_5 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000001648 158.0
WLSH2_k127_10836442_6 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000067 161.0
WLSH2_k127_10836442_7 Protein of unknown function (DUF861) K06995 - - 0.000000000000000000000000000000000001086 141.0
WLSH2_k127_10836442_8 HNH nucleases K07451 - - 0.00000000000000000000000000000000001191 145.0
WLSH2_k127_10836442_9 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000005721 145.0
WLSH2_k127_10851438_0 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 2.562e-283 894.0
WLSH2_k127_10851438_1 Aromatic ring hydroxylase K14534 - 4.2.1.120,5.3.3.3 8.501e-224 702.0
WLSH2_k127_10851438_10 methyltransferase - - - 0.0000000000000000243 91.0
WLSH2_k127_10851438_11 dehydratase - - - 0.0000000000002975 80.0
WLSH2_k127_10851438_12 Yqey-like protein K09117 - - 0.00000000001408 70.0
WLSH2_k127_10851438_13 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000002644 73.0
WLSH2_k127_10851438_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 402.0
WLSH2_k127_10851438_3 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 354.0
WLSH2_k127_10851438_4 Enoyl-(Acyl carrier protein) reductase - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 309.0
WLSH2_k127_10851438_5 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000007637 167.0
WLSH2_k127_10851438_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000116 122.0
WLSH2_k127_10851438_8 COGs COG0553 Superfamily II DNA RNA helicase SNF2 family - - - 0.00000000000000000000147 98.0
WLSH2_k127_10851438_9 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000001469 96.0
WLSH2_k127_10855019_0 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 499.0
WLSH2_k127_10855019_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 398.0
WLSH2_k127_10855019_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009158 289.0
WLSH2_k127_10855019_3 Methyltransferase domain K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000004993 119.0
WLSH2_k127_10855019_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000000001357 88.0
WLSH2_k127_10855019_6 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000009201 78.0
WLSH2_k127_10855019_8 - - - - 0.000000005287 59.0
WLSH2_k127_10855019_9 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0001219 48.0
WLSH2_k127_10856980_0 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K05898 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 499.0
WLSH2_k127_10856980_1 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002817 247.0
WLSH2_k127_10856980_10 Putative peptidoglycan binding domain - - - 0.000002213 55.0
WLSH2_k127_10856980_11 Integrase - - - 0.00001434 48.0
WLSH2_k127_10856980_2 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000001035 203.0
WLSH2_k127_10856980_3 dehydratase - - - 0.000000000000000000000000000000000000000000000000000002238 195.0
WLSH2_k127_10856980_4 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000009977 163.0
WLSH2_k127_10856980_5 HDOD domain - - - 0.0000000000000000000000003597 116.0
WLSH2_k127_10856980_6 GYD domain - - - 0.00000000000000000000009296 100.0
WLSH2_k127_10856980_7 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000001201 113.0
WLSH2_k127_10856980_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000004287 83.0
WLSH2_k127_10856980_9 Domain of unknown function DUF11 - - - 0.000000002302 60.0
WLSH2_k127_10904580_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 567.0
WLSH2_k127_10904580_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 424.0
WLSH2_k127_10904580_2 - - - - 0.0000000000000000000000000000000000000001103 154.0
WLSH2_k127_10904580_3 - - - - 0.0000000000000000000000001976 109.0
WLSH2_k127_10904580_4 - - - - 0.000000000000000000001468 96.0
WLSH2_k127_10904580_5 - - - - 0.000000000000001371 77.0
WLSH2_k127_10904580_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000007695 81.0
WLSH2_k127_10904580_7 - - - - 0.0000000001384 62.0
WLSH2_k127_10904580_8 - - - - 0.000000003487 59.0
WLSH2_k127_10904580_9 - - - - 0.0000002827 53.0
WLSH2_k127_11014380_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 490.0
WLSH2_k127_11014380_1 O-Antigen ligase - - - 0.00000000000000000000000000000000000000002122 168.0
WLSH2_k127_11014639_0 4Fe-4S dicluster domain - - - 2.171e-281 871.0
WLSH2_k127_11014639_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 484.0
WLSH2_k127_11014639_10 TPR repeat - - - 0.00000000001008 74.0
WLSH2_k127_11014639_12 HEAT-like repeat - - - 0.00000001015 64.0
WLSH2_k127_11014639_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 448.0
WLSH2_k127_11014639_3 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 421.0
WLSH2_k127_11014639_4 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 401.0
WLSH2_k127_11014639_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 400.0
WLSH2_k127_11014639_6 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 350.0
WLSH2_k127_11014639_7 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.0000000000000000000000000000000000000000000002853 172.0
WLSH2_k127_11014639_8 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000000000000000002445 141.0
WLSH2_k127_11014639_9 - - - - 0.000000000000000000000000000004207 125.0
WLSH2_k127_11057400_0 efflux pump - - - 2.466e-248 790.0
WLSH2_k127_11057400_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 586.0
WLSH2_k127_11057400_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 406.0
WLSH2_k127_11057400_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 293.0
WLSH2_k127_11057400_4 - - - - 0.0000000000000000000000000000000000000000003292 177.0
WLSH2_k127_11057400_5 methyltransferase activity - - - 0.00000000000000000000005457 109.0
WLSH2_k127_11057400_6 methyltransferase activity - - - 0.0000000000000000006304 89.0
WLSH2_k127_11057400_7 PFAM Peptidase propeptide and YPEB domain - - - 0.00000000003045 69.0
WLSH2_k127_11057400_8 Peptidase propeptide and YPEB domain - - - 0.000003833 55.0
WLSH2_k127_11109211_0 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 419.0
WLSH2_k127_11109211_1 Dehydrogenase E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 382.0
WLSH2_k127_11109211_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.00000000000000000000000000000000000000000000000000001407 193.0
WLSH2_k127_11109211_3 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.000000000000000000000000000000000000000000000000002358 192.0
WLSH2_k127_11109211_4 3-beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.000000000000000000000109 104.0
WLSH2_k127_11109211_5 C COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.0000000000000001529 83.0
WLSH2_k127_11109211_6 Aminotransferase class-III K00819 - 2.6.1.13 0.000000000364 70.0
WLSH2_k127_11111644_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.956e-272 854.0
WLSH2_k127_11111644_1 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 490.0
WLSH2_k127_11111644_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 396.0
WLSH2_k127_11111644_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 393.0
WLSH2_k127_11111644_4 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000005134 207.0
WLSH2_k127_11111644_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000006986 205.0
WLSH2_k127_11192086_0 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 445.0
WLSH2_k127_11192086_1 Plasmid stabilization system K19092 - - 0.000000000000000000000000000000000000001381 150.0
WLSH2_k127_11192086_10 Nucleotidyltransferase domain K07076 - - 0.00000000001505 69.0
WLSH2_k127_11192086_11 HEPN domain - - - 0.000005802 53.0
WLSH2_k127_11192086_13 HEPN domain K09132 - - 0.0004167 46.0
WLSH2_k127_11192086_2 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000001291 145.0
WLSH2_k127_11192086_3 START domain - - - 0.00000000000000000000000000002881 124.0
WLSH2_k127_11192086_4 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000967 119.0
WLSH2_k127_11192086_5 - - - - 0.00000000000000000000000004901 114.0
WLSH2_k127_11192086_6 HEPN domain - - - 0.000000000000000000000002779 107.0
WLSH2_k127_11192086_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000005397 101.0
WLSH2_k127_11192086_8 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000003163 100.0
WLSH2_k127_11192086_9 Nucleotidyltransferase domain - - - 0.00000000000000000009109 93.0
WLSH2_k127_11194033_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.493e-286 914.0
WLSH2_k127_11194033_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000007205 162.0
WLSH2_k127_11194033_2 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.00000000000000000000000000000008357 127.0
WLSH2_k127_11194033_3 efflux transmembrane transporter activity - - - 0.0000000000000000000001003 113.0
WLSH2_k127_11194033_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000001314 79.0
WLSH2_k127_11228589_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 447.0
WLSH2_k127_11228589_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 442.0
WLSH2_k127_11228589_10 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000009088 69.0
WLSH2_k127_11228589_11 S23 ribosomal protein - - - 0.000000418 53.0
WLSH2_k127_11228589_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 356.0
WLSH2_k127_11228589_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009957 278.0
WLSH2_k127_11228589_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000002344 219.0
WLSH2_k127_11228589_5 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000001175 201.0
WLSH2_k127_11228589_6 iron dependent repressor - - - 0.000000000000000000002284 99.0
WLSH2_k127_11228589_7 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000797 90.0
WLSH2_k127_11228589_8 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.00000000000000003386 83.0
WLSH2_k127_11228589_9 Protein of unknown function (DUF1232) - - - 0.00000000003562 71.0
WLSH2_k127_1128899_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 463.0
WLSH2_k127_1128899_1 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000003964 173.0
WLSH2_k127_1128899_2 transcriptional regulator - - - 0.00000001519 64.0
WLSH2_k127_1128899_3 - - - - 0.000006208 60.0
WLSH2_k127_1128899_4 Transcriptional regulator PadR-like family - - - 0.0005153 50.0
WLSH2_k127_11382757_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000073 162.0
WLSH2_k127_11382757_1 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000005764 156.0
WLSH2_k127_11382757_2 Bacterial membrane protein, YfhO - - - 0.000000000000000000000004687 119.0
WLSH2_k127_11382757_3 - - - - 0.0000003835 57.0
WLSH2_k127_11438954_0 Aldehyde dehydrogenase family - - - 1.212e-216 680.0
WLSH2_k127_11438954_1 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 636.0
WLSH2_k127_11438954_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 466.0
WLSH2_k127_11438954_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 406.0
WLSH2_k127_11438954_4 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000004055 153.0
WLSH2_k127_11438954_5 trisaccharide binding - - - 0.00000000000000000000000000000003124 147.0
WLSH2_k127_11438954_6 - - - - 0.00000000000000006894 94.0
WLSH2_k127_11438954_7 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000002497 79.0
WLSH2_k127_11438954_8 - - - - 0.0004677 50.0
WLSH2_k127_11458073_0 PFAM glycosyl transferase family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 2.296e-285 895.0
WLSH2_k127_11458073_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 537.0
WLSH2_k127_11458073_10 Mechanosensitive ion channel - - - 0.000000000000000002635 89.0
WLSH2_k127_11458073_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 366.0
WLSH2_k127_11458073_3 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004091 258.0
WLSH2_k127_11458073_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009479 247.0
WLSH2_k127_11458073_5 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004404 246.0
WLSH2_k127_11458073_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000005511 209.0
WLSH2_k127_11458073_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.00000000000000000000000000000000000000000000000000000001978 205.0
WLSH2_k127_11458073_8 PFAM Glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000000000000001167 194.0
WLSH2_k127_11458073_9 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000006324 159.0
WLSH2_k127_11470012_0 belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 508.0
WLSH2_k127_11470012_1 pyruvate dehydrogenase (acetyl-transferring) activity K00163 - 1.2.4.1 0.00000000009083 64.0
WLSH2_k127_1240298_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 452.0
WLSH2_k127_1240298_1 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 353.0
WLSH2_k127_1240298_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000001283 183.0
WLSH2_k127_1240298_3 Protein of unknown function (DUF2905) - - - 0.000000000000008436 77.0
WLSH2_k127_1281105_0 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003938 286.0
WLSH2_k127_1281105_1 Reversibly glycosylated polypeptide - - - 0.0000000000000000000000000000000000000000000001031 183.0
WLSH2_k127_1281105_2 transcriptional regulator K09017 - - 0.0000000000000000000003354 104.0
WLSH2_k127_1326254_0 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000279 265.0
WLSH2_k127_1326254_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000001359 218.0
WLSH2_k127_1326254_2 Smr domain - - - 0.0000000000000000000000000000001428 126.0
WLSH2_k127_1326254_3 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000005103 114.0
WLSH2_k127_1326254_4 peptidyl-tyrosine sulfation - - - 0.0001479 54.0
WLSH2_k127_1585619_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 456.0
WLSH2_k127_1585619_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 382.0
WLSH2_k127_1585619_10 Translation-initiation factor 2 K02519 - - 0.0001133 51.0
WLSH2_k127_1585619_2 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008731 279.0
WLSH2_k127_1585619_3 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000307 269.0
WLSH2_k127_1585619_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001549 253.0
WLSH2_k127_1585619_5 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000001784 159.0
WLSH2_k127_1585619_6 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000004936 143.0
WLSH2_k127_1585619_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000001559 131.0
WLSH2_k127_1585619_8 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.00000000000000000107 94.0
WLSH2_k127_1585619_9 Protein of unknown function (DUF448) K07742 - - 0.00000000005155 66.0
WLSH2_k127_1627841_0 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 426.0
WLSH2_k127_1627841_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 406.0
WLSH2_k127_1627841_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001234 234.0
WLSH2_k127_1627841_3 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000001098 216.0
WLSH2_k127_1627841_4 PFAM iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000402 211.0
WLSH2_k127_1627841_5 Protein of unknown function DUF86 - - - 0.000000000000000000008122 104.0
WLSH2_k127_1627841_6 Nucleotidyltransferase domain - - - 0.000000000000002719 80.0
WLSH2_k127_1627841_7 Nucleotidyltransferase domain - - - 0.0001261 49.0
WLSH2_k127_1692713_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 422.0
WLSH2_k127_1692713_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 342.0
WLSH2_k127_1692713_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 338.0
WLSH2_k127_1692713_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 312.0
WLSH2_k127_1692713_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000006287 160.0
WLSH2_k127_1692713_5 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000000006573 68.0
WLSH2_k127_1692713_6 PFAM methyltransferase - - - 0.000000007979 64.0
WLSH2_k127_1692713_7 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0000008224 59.0
WLSH2_k127_169528_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.221e-204 649.0
WLSH2_k127_169528_1 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 472.0
WLSH2_k127_169528_10 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000005103 195.0
WLSH2_k127_169528_11 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000001746 194.0
WLSH2_k127_169528_12 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000000000000000000002484 191.0
WLSH2_k127_169528_13 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000007994 193.0
WLSH2_k127_169528_14 Putative aminopeptidase - - - 0.00000000000000000000000000000000000000000000000002209 198.0
WLSH2_k127_169528_15 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000001335 184.0
WLSH2_k127_169528_16 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000002955 180.0
WLSH2_k127_169528_17 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000004563 167.0
WLSH2_k127_169528_18 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000002135 162.0
WLSH2_k127_169528_19 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000004814 162.0
WLSH2_k127_169528_2 tail specific protease K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 451.0
WLSH2_k127_169528_20 cell redox homeostasis - - - 0.00000000000000000000000000000000002134 142.0
WLSH2_k127_169528_21 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000002787 130.0
WLSH2_k127_169528_22 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000003614 83.0
WLSH2_k127_169528_24 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.000000000004367 69.0
WLSH2_k127_169528_25 Major facilitator Superfamily - - - 0.0000001246 53.0
WLSH2_k127_169528_26 Major Facilitator Superfamily - - - 0.000005354 55.0
WLSH2_k127_169528_3 ABC transporter, transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 445.0
WLSH2_k127_169528_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 374.0
WLSH2_k127_169528_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 325.0
WLSH2_k127_169528_6 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 281.0
WLSH2_k127_169528_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005752 264.0
WLSH2_k127_169528_8 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000002045 258.0
WLSH2_k127_169528_9 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000004742 201.0
WLSH2_k127_17403_0 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 1.021e-242 764.0
WLSH2_k127_17403_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 493.0
WLSH2_k127_17403_10 - - - - 0.0001792 48.0
WLSH2_k127_17403_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 411.0
WLSH2_k127_17403_3 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 314.0
WLSH2_k127_17403_4 PFAM Vitamin B12 dependent methionine synthase, activation domain - - - 0.000000000000000000000000000000000000000000000000000000000000001293 228.0
WLSH2_k127_17403_5 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000000000000000000000000000000000000000001658 224.0
WLSH2_k127_17403_6 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000000000000000000000003073 171.0
WLSH2_k127_17403_7 Domain of unknown function (DUF4215) - - - 0.0000000000000000000000000000001194 142.0
WLSH2_k127_17403_8 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000001773 77.0
WLSH2_k127_17403_9 - - - - 0.00000000000009273 84.0
WLSH2_k127_17627_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 335.0
WLSH2_k127_17627_1 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 301.0
WLSH2_k127_17627_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009315 285.0
WLSH2_k127_17627_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000001769 190.0
WLSH2_k127_17627_4 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000009266 157.0
WLSH2_k127_17627_5 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.00000000000000000000000000034 116.0
WLSH2_k127_17627_6 Deoxynucleoside kinase - - - 0.000000000000000000000000001136 114.0
WLSH2_k127_178293_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 540.0
WLSH2_k127_178293_1 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 442.0
WLSH2_k127_178293_10 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000001077 176.0
WLSH2_k127_178293_11 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000000000000000000000002485 173.0
WLSH2_k127_178293_12 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000003887 110.0
WLSH2_k127_178293_13 PFAM glycosyl transferase family 9 K02849 - - 0.000003382 59.0
WLSH2_k127_178293_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 412.0
WLSH2_k127_178293_3 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 357.0
WLSH2_k127_178293_4 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 336.0
WLSH2_k127_178293_5 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 327.0
WLSH2_k127_178293_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002469 272.0
WLSH2_k127_178293_7 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
WLSH2_k127_178293_8 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000002635 199.0
WLSH2_k127_178293_9 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000003656 184.0
WLSH2_k127_1784909_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 611.0
WLSH2_k127_1784909_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 484.0
WLSH2_k127_1784909_10 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000001907 247.0
WLSH2_k127_1784909_11 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000002594 237.0
WLSH2_k127_1784909_12 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000901 183.0
WLSH2_k127_1784909_13 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000004286 168.0
WLSH2_k127_1784909_14 Immune inhibitor A peptidase M6 - - - 0.00000000000000000000000000000000000005446 162.0
WLSH2_k127_1784909_15 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000006997 145.0
WLSH2_k127_1784909_16 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000523 133.0
WLSH2_k127_1784909_17 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000006513 111.0
WLSH2_k127_1784909_18 pilus assembly protein PilW K02459 - - 0.0000000000007036 80.0
WLSH2_k127_1784909_19 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.00000000003478 72.0
WLSH2_k127_1784909_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 401.0
WLSH2_k127_1784909_20 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000005389 68.0
WLSH2_k127_1784909_21 fimbrial assembly K02461 - - 0.0000000007226 71.0
WLSH2_k127_1784909_22 - - - - 0.000001025 55.0
WLSH2_k127_1784909_23 General secretion pathway protein H K02457 - - 0.000007433 56.0
WLSH2_k127_1784909_24 - K02463 - - 0.000009226 56.0
WLSH2_k127_1784909_25 type IV pilus modification protein PilV K02458 - - 0.00001653 53.0
WLSH2_k127_1784909_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 384.0
WLSH2_k127_1784909_4 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 366.0
WLSH2_k127_1784909_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 354.0
WLSH2_k127_1784909_6 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 340.0
WLSH2_k127_1784909_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 296.0
WLSH2_k127_1784909_8 Bacterial type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001993 303.0
WLSH2_k127_1784909_9 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000002249 256.0
WLSH2_k127_1821030_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 8.392e-270 844.0
WLSH2_k127_1821030_1 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000003887 240.0
WLSH2_k127_1821030_2 Protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000001825 246.0
WLSH2_k127_1821030_3 Collagen-binding surface adhesin SpaP (antigen I II family) K07337 - - 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
WLSH2_k127_1821030_4 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.00000000001505 67.0
WLSH2_k127_1822949_0 'Molybdopterin K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 458.0
WLSH2_k127_1822949_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 421.0
WLSH2_k127_1822949_10 KR domain - - - 0.000000005963 58.0
WLSH2_k127_1822949_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0001643 45.0
WLSH2_k127_1822949_2 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 322.0
WLSH2_k127_1822949_3 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002343 237.0
WLSH2_k127_1822949_4 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000479 185.0
WLSH2_k127_1822949_5 Class II Aldolase and Adducin N-terminal domain K01845 - 5.4.3.8 0.000000000000000000000000000000000158 143.0
WLSH2_k127_1822949_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000587 103.0
WLSH2_k127_1822949_7 RadC-like JAB domain K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000006285 93.0
WLSH2_k127_1822949_8 Belongs to the 'phage' integrase family - - - 0.0000000000000001057 83.0
WLSH2_k127_1822949_9 Putative addiction module component - - - 0.00000000000001752 76.0
WLSH2_k127_1909343_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 2.92e-302 953.0
WLSH2_k127_1909343_1 Belongs to the glycosyl hydrolase 57 family - - - 1.48e-196 623.0
WLSH2_k127_1909343_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 614.0
WLSH2_k127_1909343_3 Mut7-C ubiquitin K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 256.0
WLSH2_k127_1909343_4 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.00000000000000000000000000006474 116.0
WLSH2_k127_1909343_5 GGDEF domain K02488,K21025 - 2.7.7.65 0.0000000002611 69.0
WLSH2_k127_1914353_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 445.0
WLSH2_k127_1914353_1 DNA topoisomerase K02470,K02622 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000009809 264.0
WLSH2_k127_1914353_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000356 262.0
WLSH2_k127_1914353_3 PFAM PIN domain - - - 0.0000000000000000000000000000001271 129.0
WLSH2_k127_1914353_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000001646 121.0
WLSH2_k127_1914353_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000002147 116.0
WLSH2_k127_1914353_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000003346 90.0
WLSH2_k127_1914353_7 - - - - 0.0000000001722 64.0
WLSH2_k127_1914353_8 Recombinase - - - 0.0000001454 56.0
WLSH2_k127_1921553_0 Conserved region in glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1945.0
WLSH2_k127_1921553_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 3.985e-282 892.0
WLSH2_k127_1921553_10 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000138 285.0
WLSH2_k127_1921553_11 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007637 278.0
WLSH2_k127_1921553_12 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007824 261.0
WLSH2_k127_1921553_13 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
WLSH2_k127_1921553_14 Integrase - - - 0.00000000000000000000000000000000000000000000000000009279 213.0
WLSH2_k127_1921553_15 nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000000000000000000000000000000000000000001694 185.0
WLSH2_k127_1921553_16 PIN domain - - - 0.000000000000000000000000000000000000002939 150.0
WLSH2_k127_1921553_17 Soluble P-type ATPase - - - 0.00000000000000000000000000000000002171 141.0
WLSH2_k127_1921553_18 - - - - 0.00000000000000000000000000000000003892 144.0
WLSH2_k127_1921553_19 DDE_Tnp_1-associated - - - 0.0000000000000000000000000000001242 132.0
WLSH2_k127_1921553_2 Pyridoxal-phosphate dependent enzyme K01883 - 6.1.1.16 4.048e-268 849.0
WLSH2_k127_1921553_20 Filamentation induced by cAMP protein fic - - - 0.0000000000000000000000000000001857 137.0
WLSH2_k127_1921553_21 nucleotidyltransferase activity K07076 - - 0.00000000000000000000008382 102.0
WLSH2_k127_1921553_22 Protein of unknown function (DUF2281) - - - 0.00000000000000001546 84.0
WLSH2_k127_1921553_23 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.0000000000000006732 80.0
WLSH2_k127_1921553_24 Transposase IS66 family K07484 - - 0.0000000000000163 81.0
WLSH2_k127_1921553_25 Domain of unknown function (DUF4338) - - - 0.0000000000003992 72.0
WLSH2_k127_1921553_26 Helix-turn-helix domain - - - 0.000000000001463 72.0
WLSH2_k127_1921553_27 defense response to virus - - - 0.000001187 58.0
WLSH2_k127_1921553_29 Transposase and inactivated derivatives K07498 - - 0.0008709 49.0
WLSH2_k127_1921553_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 2.513e-254 811.0
WLSH2_k127_1921553_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 7.49e-232 723.0
WLSH2_k127_1921553_5 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 598.0
WLSH2_k127_1921553_6 Cys Met metabolism pyridoxal-phosphate-dependent protein K01739,K01760 - 2.5.1.48,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 472.0
WLSH2_k127_1921553_7 Bacterial regulatory protein, Fis family K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 449.0
WLSH2_k127_1921553_8 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 436.0
WLSH2_k127_1921553_9 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 382.0
WLSH2_k127_1947953_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 349.0
WLSH2_k127_1947953_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000002066 186.0
WLSH2_k127_1947953_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000009332 186.0
WLSH2_k127_1947953_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000004208 180.0
WLSH2_k127_1947953_4 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000004417 84.0
WLSH2_k127_1947953_5 hydrolase activity, acting on ester bonds - - - 0.0000000001063 68.0
WLSH2_k127_1962793_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1052.0
WLSH2_k127_1962793_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 387.0
WLSH2_k127_1962793_2 Extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009005 362.0
WLSH2_k127_1962793_3 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 300.0
WLSH2_k127_1962793_4 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002226 278.0
WLSH2_k127_1962793_5 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000003118 234.0
WLSH2_k127_1962793_6 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000001553 222.0
WLSH2_k127_1962793_7 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000003772 211.0
WLSH2_k127_1962793_8 - - - - 0.0000000000000000000000000000000005148 145.0
WLSH2_k127_1962793_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000002193 137.0
WLSH2_k127_1967244_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 603.0
WLSH2_k127_1967244_1 Integrase - - - 0.00000000000000000000000000000000000000000000000000000006113 201.0
WLSH2_k127_1967244_2 Transglycosylase - - - 0.0000000000000000000000000000003412 131.0
WLSH2_k127_1967244_3 Integrase - - - 0.00000000000000000000000000581 117.0
WLSH2_k127_1967244_4 PFAM UspA domain protein - - - 0.000000000001169 75.0
WLSH2_k127_1967244_5 Transposase IS4 family protein - - - 0.0001422 45.0
WLSH2_k127_2013513_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein K00239,K00244 - 1.3.5.1,1.3.5.4 4.993e-284 884.0
WLSH2_k127_2013513_1 PFAM AMP-dependent synthetase and ligase - - - 1.732e-228 724.0
WLSH2_k127_2013513_10 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000473 117.0
WLSH2_k127_2013513_11 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02768,K02806 - 2.7.1.202 0.000000000000000001479 96.0
WLSH2_k127_2013513_12 - - - - 0.000000000000000422 83.0
WLSH2_k127_2013513_13 Protein of unknown function (DUF1329) - - - 0.0000000002613 73.0
WLSH2_k127_2013513_14 metalloendopeptidase activity K06261,K08867,K09187,K14972,K20371 - 2.1.1.43,2.7.11.1 0.000001132 62.0
WLSH2_k127_2013513_15 hydrolase - GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901575 - 0.00008782 48.0
WLSH2_k127_2013513_2 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 474.0
WLSH2_k127_2013513_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 375.0
WLSH2_k127_2013513_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006099,GO:0006101,GO:0006108,GO:0006113,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009060,GO:0009061,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015980,GO:0016020,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019898,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045333,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 378.0
WLSH2_k127_2013513_5 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 353.0
WLSH2_k127_2013513_6 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 353.0
WLSH2_k127_2013513_7 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002494 284.0
WLSH2_k127_2013513_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000001324 166.0
WLSH2_k127_2013513_9 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000009353 167.0
WLSH2_k127_2017672_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.95e-236 741.0
WLSH2_k127_2017672_1 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 429.0
WLSH2_k127_2017672_2 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000002527 235.0
WLSH2_k127_2088260_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000003293 251.0
WLSH2_k127_2088260_1 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000008822 221.0
WLSH2_k127_2088260_2 protein conserved in bacteria K09803 - - 0.000000000000000000004102 96.0
WLSH2_k127_2088260_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000232 91.0
WLSH2_k127_2088260_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000002458 102.0
WLSH2_k127_2088260_5 CopG antitoxin of type II toxin-antitoxin system - - - 0.00000000000007101 74.0
WLSH2_k127_2088260_6 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000008341 68.0
WLSH2_k127_2093996_0 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 319.0
WLSH2_k127_2093996_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000007404 188.0
WLSH2_k127_2093996_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000009327 172.0
WLSH2_k127_2093996_3 DNA-binding transcription factor activity - - - 0.00000000000000000000000002683 114.0
WLSH2_k127_2097226_0 4Fe-4S dicluster domain K00184 - - 1.013e-318 1005.0
WLSH2_k127_2097226_1 Protein of unknown function, DUF255 K06888 - - 1.707e-284 889.0
WLSH2_k127_2097226_10 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 364.0
WLSH2_k127_2097226_11 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 311.0
WLSH2_k127_2097226_12 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 291.0
WLSH2_k127_2097226_13 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 284.0
WLSH2_k127_2097226_14 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 292.0
WLSH2_k127_2097226_15 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002564 284.0
WLSH2_k127_2097226_16 GDP-mannose 4,6 dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008892 281.0
WLSH2_k127_2097226_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004907 276.0
WLSH2_k127_2097226_18 PFAM cytochrome c oxidase, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000002883 257.0
WLSH2_k127_2097226_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000009084 240.0
WLSH2_k127_2097226_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B - - - 4.462e-280 873.0
WLSH2_k127_2097226_20 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000004612 234.0
WLSH2_k127_2097226_21 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000007806 232.0
WLSH2_k127_2097226_22 iron-sulfur cluster assembly K07400,K13628 - - 0.00000000000000000000000000000000000000000000000000000003399 202.0
WLSH2_k127_2097226_23 protein histidine kinase activity K03407,K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000407 194.0
WLSH2_k127_2097226_24 response regulator - - - 0.0000000000000000000000000000000000000000000006075 177.0
WLSH2_k127_2097226_25 Domain of unknown function (DUF1848) - - - 0.000000000000000000000000000000000000000000009897 175.0
WLSH2_k127_2097226_26 response regulator - - - 0.0000000000000000000000000000000000000000005642 169.0
WLSH2_k127_2097226_27 HDOD domain - - - 0.00000000000000000000000000000000000005056 154.0
WLSH2_k127_2097226_28 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000003418 144.0
WLSH2_k127_2097226_29 response regulator, receiver - - - 0.0000000000000000000000000000000000842 138.0
WLSH2_k127_2097226_3 PFAM Polysulphide reductase, NrfD - - - 2.47e-243 758.0
WLSH2_k127_2097226_30 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000001405 132.0
WLSH2_k127_2097226_31 response regulator, receiver - - - 0.0000000000000000000000000000001564 127.0
WLSH2_k127_2097226_32 - - - - 0.0000000000000000000000000000006012 133.0
WLSH2_k127_2097226_33 Transcriptional regulator - - - 0.000000000000000000000000000004547 125.0
WLSH2_k127_2097226_34 PFAM histidine kinase A domain protein - - - 0.0000000000000000000000000009255 122.0
WLSH2_k127_2097226_36 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000004454 83.0
WLSH2_k127_2097226_37 Integrase - - - 0.000000000000421 70.0
WLSH2_k127_2097226_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 553.0
WLSH2_k127_2097226_5 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009368 533.0
WLSH2_k127_2097226_6 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 478.0
WLSH2_k127_2097226_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 467.0
WLSH2_k127_2097226_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 418.0
WLSH2_k127_2097226_9 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 359.0
WLSH2_k127_2108808_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 596.0
WLSH2_k127_2108808_1 acyl-coa dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 583.0
WLSH2_k127_2108808_10 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000003095 138.0
WLSH2_k127_2108808_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.00000000000000000000000000000000003146 142.0
WLSH2_k127_2108808_12 sequence-specific DNA binding - - - 0.00000000000000000000000000008012 118.0
WLSH2_k127_2108808_13 Rv0623-like transcription factor K19687 - - 0.000000000000000004003 87.0
WLSH2_k127_2108808_14 Bacterial regulatory proteins, tetR family - - - 0.000000000000009391 83.0
WLSH2_k127_2108808_2 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 419.0
WLSH2_k127_2108808_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 385.0
WLSH2_k127_2108808_4 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003854 272.0
WLSH2_k127_2108808_5 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005629 260.0
WLSH2_k127_2108808_6 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000002902 246.0
WLSH2_k127_2108808_7 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000008703 214.0
WLSH2_k127_2108808_8 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000006227 180.0
WLSH2_k127_2108808_9 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000000000000001094 155.0
WLSH2_k127_2138615_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 460.0
WLSH2_k127_2138615_1 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 299.0
WLSH2_k127_2138615_10 Protein of unknown function (DUF433) - - - 0.000000000000000001218 92.0
WLSH2_k127_2138615_11 - K07726 - - 0.0000663 50.0
WLSH2_k127_2138615_13 TonB C terminal K03832 - - 0.0006761 51.0
WLSH2_k127_2138615_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001092 285.0
WLSH2_k127_2138615_3 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000001271 219.0
WLSH2_k127_2138615_4 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000003343 132.0
WLSH2_k127_2138615_5 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000004659 126.0
WLSH2_k127_2138615_6 DNA primase small subunit - - - 0.000000000000000000000000000001912 126.0
WLSH2_k127_2138615_7 - - - - 0.0000000000000000000000000009255 120.0
WLSH2_k127_2138615_8 - - - - 0.00000000000000000000000007932 111.0
WLSH2_k127_2138615_9 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000008365 106.0
WLSH2_k127_2181269_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.023e-237 742.0
WLSH2_k127_2181269_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.257e-222 695.0
WLSH2_k127_2181269_10 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000008041 243.0
WLSH2_k127_2181269_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000007222 148.0
WLSH2_k127_2181269_12 R3H domain protein K06346 - - 0.000000000000000000000000000000000007111 148.0
WLSH2_k127_2181269_13 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000006465 127.0
WLSH2_k127_2181269_14 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000003286 106.0
WLSH2_k127_2181269_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000001023 79.0
WLSH2_k127_2181269_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000009053 74.0
WLSH2_k127_2181269_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000008738 73.0
WLSH2_k127_2181269_18 Bacterial regulatory proteins, tetR family - - - 0.00000000004933 71.0
WLSH2_k127_2181269_19 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000001323 57.0
WLSH2_k127_2181269_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 484.0
WLSH2_k127_2181269_20 Virulence activator alpha C-term - - - 0.000003662 56.0
WLSH2_k127_2181269_21 - - - - 0.0003889 48.0
WLSH2_k127_2181269_3 glutamate--cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 391.0
WLSH2_k127_2181269_4 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 384.0
WLSH2_k127_2181269_5 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 321.0
WLSH2_k127_2181269_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003058 291.0
WLSH2_k127_2181269_7 PFAM MltA domain protein K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 282.0
WLSH2_k127_2181269_8 PFAM YkuD domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005375 274.0
WLSH2_k127_2181269_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005527 249.0
WLSH2_k127_2229853_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.309e-235 741.0
WLSH2_k127_2229853_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 522.0
WLSH2_k127_2229853_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 380.0
WLSH2_k127_2229853_3 - - - - 0.0000000000000000000000000004939 121.0
WLSH2_k127_2240508_0 Acetyltransferase (GNAT) domain K01905,K09181,K22224 - 6.2.1.13 0.0 1095.0
WLSH2_k127_2240508_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.772e-272 846.0
WLSH2_k127_2240508_10 - - - - 0.000000000000007136 74.0
WLSH2_k127_2240508_11 Phosphate-selective porin O and P K07221 - - 0.000000000007362 75.0
WLSH2_k127_2240508_12 DsrC like protein K11179,K17218 - 1.8.5.4 0.000000000008519 74.0
WLSH2_k127_2240508_13 PAS fold K02491 - 2.7.13.3 0.0000000007434 72.0
WLSH2_k127_2240508_14 Histidine kinase - - - 0.000004824 53.0
WLSH2_k127_2240508_15 Sigma-54 factor interaction domain-containing protein K07713 - - 0.00004571 52.0
WLSH2_k127_2240508_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001634 277.0
WLSH2_k127_2240508_3 response regulator receiver K13041 - - 0.0000000000000000000000000000000000000000000000000004069 196.0
WLSH2_k127_2240508_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000264 193.0
WLSH2_k127_2240508_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000002726 199.0
WLSH2_k127_2240508_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000002502 181.0
WLSH2_k127_2240508_7 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000000001044 135.0
WLSH2_k127_2240508_8 Phosphopantetheine attachment site - - - 0.0000000000000000001528 90.0
WLSH2_k127_2240508_9 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000007577 89.0
WLSH2_k127_2244179_0 arsenical-resistance protein K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009909 514.0
WLSH2_k127_2244179_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 461.0
WLSH2_k127_2244179_10 Thioredoxin domain - - - 0.00000000000000000000009435 99.0
WLSH2_k127_2244179_11 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000009155 94.0
WLSH2_k127_2244179_12 Integrase - - - 0.00000000000000001128 86.0
WLSH2_k127_2244179_13 Thioredoxin domain - - - 0.0000000002365 64.0
WLSH2_k127_2244179_14 Domain of unknown function (DUF4215) - - - 0.0000004167 62.0
WLSH2_k127_2244179_15 Putative peptidoglycan binding domain - - - 0.00001955 52.0
WLSH2_k127_2244179_16 Predicted permease K07089 - - 0.0002207 45.0
WLSH2_k127_2244179_17 NHL repeat - - - 0.0003777 48.0
WLSH2_k127_2244179_2 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 444.0
WLSH2_k127_2244179_3 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001192 274.0
WLSH2_k127_2244179_4 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000326 220.0
WLSH2_k127_2244179_5 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000000000000002298 175.0
WLSH2_k127_2244179_6 PIN domain K07062 - - 0.00000000000000000000000000000000000000000000002886 173.0
WLSH2_k127_2244179_7 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000002052 151.0
WLSH2_k127_2244179_8 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.0000000000000000000000000000000000002276 142.0
WLSH2_k127_2244179_9 - - - - 0.0000000000000000000000000001232 121.0
WLSH2_k127_227042_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.734e-254 793.0
WLSH2_k127_227042_1 Radical SAM K18563 - - 1.572e-208 661.0
WLSH2_k127_227042_10 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 316.0
WLSH2_k127_227042_11 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009808 276.0
WLSH2_k127_227042_12 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006478 277.0
WLSH2_k127_227042_13 Von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001291 293.0
WLSH2_k127_227042_14 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000001048 226.0
WLSH2_k127_227042_15 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000418 217.0
WLSH2_k127_227042_16 SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000002795 209.0
WLSH2_k127_227042_17 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000003273 177.0
WLSH2_k127_227042_18 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000002277 172.0
WLSH2_k127_227042_19 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000001077 172.0
WLSH2_k127_227042_2 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 509.0
WLSH2_k127_227042_20 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000001071 149.0
WLSH2_k127_227042_21 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000003461 139.0
WLSH2_k127_227042_22 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000005275 115.0
WLSH2_k127_227042_23 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001559 104.0
WLSH2_k127_227042_24 KH domain K06960 - - 0.000000000000000000000005537 103.0
WLSH2_k127_227042_25 PIN domain K18828 - - 0.0000000000000000002959 96.0
WLSH2_k127_227042_26 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000001503 83.0
WLSH2_k127_227042_27 Putative antitoxin - - - 0.000000000000003407 78.0
WLSH2_k127_227042_28 - - - - 0.00000000000002261 74.0
WLSH2_k127_227042_29 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000269 77.0
WLSH2_k127_227042_3 Belongs to the DEAD box helicase family K03732,K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 505.0
WLSH2_k127_227042_30 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.00000000002897 70.0
WLSH2_k127_227042_31 Protein of unknown function (DUF507) - - - 0.000000009909 60.0
WLSH2_k127_227042_32 Protein of unknown function (DUF507) - - - 0.00002219 50.0
WLSH2_k127_227042_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 477.0
WLSH2_k127_227042_5 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 432.0
WLSH2_k127_227042_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 409.0
WLSH2_k127_227042_7 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 392.0
WLSH2_k127_227042_8 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 316.0
WLSH2_k127_227042_9 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
WLSH2_k127_2358839_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.896e-291 908.0
WLSH2_k127_2358839_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 597.0
WLSH2_k127_2358839_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000007778 130.0
WLSH2_k127_2378154_0 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006191 259.0
WLSH2_k127_2378154_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000001827 230.0
WLSH2_k127_2378154_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000002038 208.0
WLSH2_k127_2378154_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000002944 171.0
WLSH2_k127_2378154_4 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000008989 160.0
WLSH2_k127_2378154_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000116 61.0
WLSH2_k127_2378154_6 Protein of unknown function (DUF3426) - - - 0.000000002409 68.0
WLSH2_k127_2378154_7 protein secretion K03116,K03425 GO:0003674,GO:0005215 - 0.0000166 49.0
WLSH2_k127_2411298_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000006896 212.0
WLSH2_k127_2411298_1 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000001988 193.0
WLSH2_k127_2411298_2 addiction module antidote protein HigA K21498 - - 0.0000000000000000000000000000000000000003565 152.0
WLSH2_k127_2411298_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000000000000006608 144.0
WLSH2_k127_2411298_4 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000007943 158.0
WLSH2_k127_2411298_5 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000004587 131.0
WLSH2_k127_2411298_6 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000001476 87.0
WLSH2_k127_2411298_7 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000007084 72.0
WLSH2_k127_2432001_0 Multi-sensor signal transduction multi-kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002092 265.0
WLSH2_k127_2432001_1 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000001428 238.0
WLSH2_k127_2432001_2 Histidine kinase K02030 - - 0.00000000000000000000000000000000000001321 168.0
WLSH2_k127_2432001_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000002263 141.0
WLSH2_k127_2432001_4 GAF domain - - - 0.00000000000000000004869 103.0
WLSH2_k127_2490778_0 Sodium:neurotransmitter symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 563.0
WLSH2_k127_2490778_1 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 294.0
WLSH2_k127_2490778_2 PIN domain - - - 0.000000000000000000000000000000000000000000002823 172.0
WLSH2_k127_2490778_4 self proteolysis - - - 0.00000000000000001934 87.0
WLSH2_k127_2496602_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003925 254.0
WLSH2_k127_2496602_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000003535 188.0
WLSH2_k127_2496602_2 Transposase - - - 0.0000000000000000000000000000000000000000000000006665 183.0
WLSH2_k127_2496602_3 - - - - 0.0000000000000000000000000000000000002837 153.0
WLSH2_k127_2498799_0 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0 1210.0
WLSH2_k127_2498799_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.334e-211 698.0
WLSH2_k127_2498799_10 Penicillin amidase K01434 - 3.5.1.11 0.00000000005044 64.0
WLSH2_k127_2498799_2 secondary active sulfate transmembrane transporter activity K06901 - - 9.335e-197 630.0
WLSH2_k127_2498799_3 His Kinase A (phosphoacceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 414.0
WLSH2_k127_2498799_4 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000009849 198.0
WLSH2_k127_2498799_5 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000006657 193.0
WLSH2_k127_2498799_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000006978 183.0
WLSH2_k127_2498799_7 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000001546 94.0
WLSH2_k127_2498799_8 - - - - 0.00000000000000002248 91.0
WLSH2_k127_2498799_9 - K22017 GO:0001894,GO:0002218,GO:0002220,GO:0002223,GO:0002253,GO:0002376,GO:0002429,GO:0002682,GO:0002684,GO:0002757,GO:0002758,GO:0002764,GO:0002768,GO:0003008,GO:0003674,GO:0005102,GO:0005176,GO:0005198,GO:0005201,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005796,GO:0005886,GO:0005887,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0007154,GO:0007165,GO:0007166,GO:0007586,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0010669,GO:0012505,GO:0016020,GO:0016021,GO:0016266,GO:0019538,GO:0022600,GO:0023052,GO:0030197,GO:0030277,GO:0031012,GO:0031224,GO:0031226,GO:0031347,GO:0031349,GO:0031974,GO:0032501,GO:0034645,GO:0036211,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0048871,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060249,GO:0065007,GO:0065008,GO:0070013,GO:0070085,GO:0071704,GO:0071944,GO:0080134,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000007816 84.0
WLSH2_k127_2499505_0 Sodium:sulfate symporter transmembrane region K14445 - - 5.798e-208 659.0
WLSH2_k127_2499505_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 364.0
WLSH2_k127_2499505_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000001041 140.0
WLSH2_k127_2499505_11 PFAM CBS domain - - - 0.00000000000000000000000000005991 126.0
WLSH2_k127_2499505_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 341.0
WLSH2_k127_2499505_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 327.0
WLSH2_k127_2499505_4 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003047 277.0
WLSH2_k127_2499505_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000004846 203.0
WLSH2_k127_2499505_6 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.000000000000000000000000000000000000000000000000000002852 198.0
WLSH2_k127_2499505_7 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000004007 181.0
WLSH2_k127_2499505_8 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000104 145.0
WLSH2_k127_2499505_9 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000001078 137.0
WLSH2_k127_2512815_0 COG1070 Sugar (pentulose and hexulose) kinases K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 593.0
WLSH2_k127_2512815_1 Belongs to the thiolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 546.0
WLSH2_k127_2512815_10 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
WLSH2_k127_2512815_11 MaoC like domain - - - 0.000000000000000000000000000000000000000002842 164.0
WLSH2_k127_2512815_12 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000002731 102.0
WLSH2_k127_2512815_13 RTX toxins and related Ca2 binding proteins - - - 0.000000000000000000000003068 113.0
WLSH2_k127_2512815_14 Domain of unknown function (DUF362) - - - 0.0000000000000000003841 102.0
WLSH2_k127_2512815_16 Permeases of the drug metabolite transporter - - - 0.000000003813 67.0
WLSH2_k127_2512815_17 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000007946 59.0
WLSH2_k127_2512815_2 COG0183 Acetyl-CoA acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 484.0
WLSH2_k127_2512815_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 455.0
WLSH2_k127_2512815_4 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 450.0
WLSH2_k127_2512815_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 444.0
WLSH2_k127_2512815_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 381.0
WLSH2_k127_2512815_7 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 348.0
WLSH2_k127_2512815_8 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 348.0
WLSH2_k127_2512815_9 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 332.0
WLSH2_k127_2518583_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1669.0
WLSH2_k127_2518583_1 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000008891 93.0
WLSH2_k127_2536745_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000004231 186.0
WLSH2_k127_2536745_1 COG3039 Transposase and inactivated derivatives, IS5 family K07481 - - 0.0001915 51.0
WLSH2_k127_2548472_0 phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 602.0
WLSH2_k127_2548472_1 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 572.0
WLSH2_k127_2548472_10 Nucleotidyltransferase domain - - - 0.00000001857 63.0
WLSH2_k127_2548472_11 type III restriction enzyme, res subunit - - - 0.0000002981 59.0
WLSH2_k127_2548472_12 nuclease activity - - - 0.00004522 49.0
WLSH2_k127_2548472_13 SpoVT / AbrB like domain - - - 0.00009303 49.0
WLSH2_k127_2548472_2 COG0226 ABC-type phosphate transport system periplasmic K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 433.0
WLSH2_k127_2548472_3 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 416.0
WLSH2_k127_2548472_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 399.0
WLSH2_k127_2548472_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 372.0
WLSH2_k127_2548472_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009614 265.0
WLSH2_k127_2548472_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000006072 223.0
WLSH2_k127_2548472_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.27 0.00000000000000000000000000000000000000000000000001584 188.0
WLSH2_k127_2548472_9 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000001284 74.0
WLSH2_k127_256324_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1215.0
WLSH2_k127_256324_1 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 303.0
WLSH2_k127_256324_2 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0000000000000000000000000000000000000002756 160.0
WLSH2_k127_256324_3 Rubrerythrin - - - 0.0000000000000000000000000007243 113.0
WLSH2_k127_256324_4 flavin adenine dinucleotide binding - - - 0.000000000000000000000008477 111.0
WLSH2_k127_2691928_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000006194 244.0
WLSH2_k127_2691928_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000006658 230.0
WLSH2_k127_2691928_2 - - - - 0.000000000000000000000000000000000000003121 168.0
WLSH2_k127_2694187_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1140.0
WLSH2_k127_2694187_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.322e-244 766.0
WLSH2_k127_2694187_10 ATPase associated with various cellular activities AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 351.0
WLSH2_k127_2694187_11 PFAM ABC transporter related K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 337.0
WLSH2_k127_2694187_12 chorismate binding enzyme K01657,K01665,K03342,K13503,K13950 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 325.0
WLSH2_k127_2694187_13 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 310.0
WLSH2_k127_2694187_14 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 303.0
WLSH2_k127_2694187_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001874 261.0
WLSH2_k127_2694187_16 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000002277 241.0
WLSH2_k127_2694187_17 Cytidylyltransferase K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000009027 231.0
WLSH2_k127_2694187_18 Amino-transferase class IV K00824,K00826 - 2.6.1.21,2.6.1.42 0.000000000000000000000000000000000000000000000000000000003493 214.0
WLSH2_k127_2694187_19 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000002384 211.0
WLSH2_k127_2694187_2 asparaginyl-tRNA synthetase K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 599.0
WLSH2_k127_2694187_20 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000002713 165.0
WLSH2_k127_2694187_22 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000009048 162.0
WLSH2_k127_2694187_23 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000001676 137.0
WLSH2_k127_2694187_24 recA bacterial DNA recombination protein - - - 0.000000000000000000000001117 112.0
WLSH2_k127_2694187_25 Protein tyrosine kinase - - - 0.000000000000000001158 101.0
WLSH2_k127_2694187_26 phosphocarrier protein HPr K11189 - - 0.00000000000000000868 86.0
WLSH2_k127_2694187_27 OstA-like protein K09774 - - 0.000000000001899 77.0
WLSH2_k127_2694187_28 VanZ like family - - - 0.00000000003087 70.0
WLSH2_k127_2694187_29 deoxyhypusine monooxygenase activity - - - 0.00002642 56.0
WLSH2_k127_2694187_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 559.0
WLSH2_k127_2694187_30 - - - - 0.00005115 53.0
WLSH2_k127_2694187_32 Lipopolysaccharide-assembly, LptC-related - - - 0.0002943 51.0
WLSH2_k127_2694187_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 526.0
WLSH2_k127_2694187_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 477.0
WLSH2_k127_2694187_6 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 443.0
WLSH2_k127_2694187_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 427.0
WLSH2_k127_2694187_8 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 385.0
WLSH2_k127_2694187_9 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 359.0
WLSH2_k127_2694512_0 Alpha-glucan phosphorylase K00688 - 2.4.1.1 8.74e-322 1005.0
WLSH2_k127_2694512_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000001806 209.0
WLSH2_k127_2694512_2 Cold shock K03704 - - 0.0000000000001071 73.0
WLSH2_k127_2703037_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 490.0
WLSH2_k127_2703037_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 452.0
WLSH2_k127_2703037_2 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001676 237.0
WLSH2_k127_2703037_3 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000003591 209.0
WLSH2_k127_2703037_4 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000002827 177.0
WLSH2_k127_2703037_5 acyl-CoA dehydrogenase K14448 - 1.3.8.12 0.00000000015 67.0
WLSH2_k127_2742604_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 456.0
WLSH2_k127_2742604_1 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000002581 160.0
WLSH2_k127_2742604_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000005526 79.0
WLSH2_k127_2742604_3 - - - - 0.0000001649 59.0
WLSH2_k127_2742604_4 Possibly the antitoxin component of a type II toxin- antitoxin (TA) system - - - 0.0002372 48.0
WLSH2_k127_27705_0 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 528.0
WLSH2_k127_27705_1 extracellular matrix structural constituent - - - 0.0000000000000000000005664 109.0
WLSH2_k127_27705_2 ATPase (AAA superfamily - - - 0.00005495 48.0
WLSH2_k127_2813151_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 9.185e-215 676.0
WLSH2_k127_2813151_1 Belongs to the thiolase family K00626 - 2.3.1.9 3.279e-206 647.0
WLSH2_k127_2813151_10 Domain of unknown function (DUF4338) - - - 0.0000005318 54.0
WLSH2_k127_2813151_2 transposition, DNA-mediated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 389.0
WLSH2_k127_2813151_3 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000005566 231.0
WLSH2_k127_2813151_4 Domain of unknown function (DUF4258) - - - 0.00000000000003256 77.0
WLSH2_k127_2813151_5 Flavin containing amine oxidoreductase - - - 0.00000000000154 76.0
WLSH2_k127_2813151_6 - - - - 0.000000000004938 72.0
WLSH2_k127_2813151_7 - - - - 0.0000000003455 64.0
WLSH2_k127_2813151_8 - - - - 0.000000001376 63.0
WLSH2_k127_2813151_9 Domain of unknown function (DUF4338) - - - 0.000000001674 60.0
WLSH2_k127_2824669_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000003758 117.0
WLSH2_k127_2824669_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000001826 98.0
WLSH2_k127_2824669_2 mRNA binding K07339 - - 0.0000000000000000000007396 97.0
WLSH2_k127_2824669_3 Gaf domain - - - 0.00000000000000298 83.0
WLSH2_k127_2824669_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000904 54.0
WLSH2_k127_2830261_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000008178 119.0
WLSH2_k127_2830261_1 PFAM membrane bound O-acyl transferase MBOAT family protein - - - 0.000000000000000000000002466 104.0
WLSH2_k127_2830261_2 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000739 78.0
WLSH2_k127_2830261_3 glycosyl transferase, family 39 - - - 0.000000000002109 79.0
WLSH2_k127_2830261_4 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.000003652 51.0
WLSH2_k127_2830261_5 arylsulfatase activity - - - 0.0000344 56.0
WLSH2_k127_2967555_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K02182 - 6.2.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 610.0
WLSH2_k127_2967555_1 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 482.0
WLSH2_k127_2967555_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 390.0
WLSH2_k127_2967555_3 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000006415 199.0
WLSH2_k127_2967555_4 Hydrogenase maturation protease K03605 - - 0.000000000000000000000001549 110.0
WLSH2_k127_2967555_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388,K03616,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000001456 91.0
WLSH2_k127_2967555_6 Domain of unknown function (DUF4139) - - - 0.00003243 50.0
WLSH2_k127_2985439_0 PFAM AMP-dependent synthetase and ligase - - - 0.0 1571.0
WLSH2_k127_2985439_1 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 320.0
WLSH2_k127_2985439_2 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001335 285.0
WLSH2_k127_2985439_3 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000004942 211.0
WLSH2_k127_2985439_4 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000003103 108.0
WLSH2_k127_2985439_5 PFAM MbtH domain protein K05375,K09190 - - 0.000000000000000004556 85.0
WLSH2_k127_2985439_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.0002177 44.0
WLSH2_k127_2993341_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000649 272.0
WLSH2_k127_2993341_1 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000003599 179.0
WLSH2_k127_2993341_2 4 iron, 4 sulfur cluster binding K05524 GO:0001666,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0009628,GO:0036293,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0070482,GO:0075136 - 0.000000000000000000000000000000000007491 140.0
WLSH2_k127_2993341_3 3-dehydroquinate dehydratase activity K03785,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009712,GO:0009713,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018958,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0042537,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046189,GO:0046278,GO:0046279,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901615,GO:1901617 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000752 140.0
WLSH2_k127_2993341_4 Peptidase family C69 K14358 - - 0.0000000000000000000000000001049 118.0
WLSH2_k127_2993341_5 PFAM conserved K07027 - - 0.000000000000000000000002349 115.0
WLSH2_k127_3041462_0 AMP-binding enzyme K02182 - 6.2.1.48 3.871e-200 636.0
WLSH2_k127_3041462_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 479.0
WLSH2_k127_3041462_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 416.0
WLSH2_k127_3041462_3 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 294.0
WLSH2_k127_3041462_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
WLSH2_k127_3041462_5 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000001197 197.0
WLSH2_k127_3041462_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000001157 195.0
WLSH2_k127_3041462_7 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.000000000000004534 79.0
WLSH2_k127_3061348_0 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.2 5.283e-238 743.0
WLSH2_k127_3061348_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500,K11392,K21970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 341.0
WLSH2_k127_3061348_10 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000002036 76.0
WLSH2_k127_3061348_11 - - - - 0.00007088 48.0
WLSH2_k127_3061348_12 Bacterial SH3 domain homologues - - - 0.0003266 51.0
WLSH2_k127_3061348_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 303.0
WLSH2_k127_3061348_3 Peptidase family C69 K14358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002745 257.0
WLSH2_k127_3061348_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000002657 244.0
WLSH2_k127_3061348_5 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000008012 188.0
WLSH2_k127_3061348_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000005131 176.0
WLSH2_k127_3061348_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000009233 146.0
WLSH2_k127_3061348_8 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000000000000495 136.0
WLSH2_k127_3061348_9 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000002292 79.0
WLSH2_k127_3110636_0 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 385.0
WLSH2_k127_3110636_1 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 318.0
WLSH2_k127_3110636_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 289.0
WLSH2_k127_3110636_3 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000003844 236.0
WLSH2_k127_3110636_4 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000502 233.0
WLSH2_k127_3110636_5 ribonuclease BN - - - 0.00000000005006 72.0
WLSH2_k127_3110636_6 CBS domain - - - 0.0000000009617 66.0
WLSH2_k127_3111695_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 488.0
WLSH2_k127_3111695_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 410.0
WLSH2_k127_3111695_2 KR domain K00059 GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 353.0
WLSH2_k127_3111695_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 310.0
WLSH2_k127_3111695_4 Acyl dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003008 256.0
WLSH2_k127_3150026_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 478.0
WLSH2_k127_3150026_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000008263 198.0
WLSH2_k127_3150026_2 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000007167 153.0
WLSH2_k127_3150026_3 HD domain - - - 0.00000000000000000003595 98.0
WLSH2_k127_3150026_4 transcription factor binding - - - 0.0000000000000000000532 105.0
WLSH2_k127_3150026_5 PFAM ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.0000000000007366 82.0
WLSH2_k127_3163818_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1102.0
WLSH2_k127_3163818_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 6.661e-200 629.0
WLSH2_k127_3163818_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002845 193.0
WLSH2_k127_3163818_11 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000003129 186.0
WLSH2_k127_3163818_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000001202 148.0
WLSH2_k127_3163818_13 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000003902 110.0
WLSH2_k127_3163818_14 Dodecin K09165 - - 0.000000000000001868 78.0
WLSH2_k127_3163818_15 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000002431 76.0
WLSH2_k127_3163818_2 PFAM CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 429.0
WLSH2_k127_3163818_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 301.0
WLSH2_k127_3163818_4 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004784 289.0
WLSH2_k127_3163818_5 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003339 276.0
WLSH2_k127_3163818_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000005196 247.0
WLSH2_k127_3163818_7 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000003465 228.0
WLSH2_k127_3163818_8 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000002781 214.0
WLSH2_k127_3163818_9 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000006565 227.0
WLSH2_k127_3172126_0 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000008545 210.0
WLSH2_k127_3172126_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000002122 160.0
WLSH2_k127_3172126_2 Integrase - - - 0.000000000000000000000007245 107.0
WLSH2_k127_3172126_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000439 46.0
WLSH2_k127_3241273_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 441.0
WLSH2_k127_3241273_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 334.0
WLSH2_k127_3241273_2 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000004343 213.0
WLSH2_k127_3241273_3 Aldo/keto reductase family - - - 0.000000000000000000000000000001072 123.0
WLSH2_k127_3249611_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1517.0
WLSH2_k127_3249611_1 Rieske-like [2Fe-2S] domain K05710,K14578 - - 0.000000000000000000000002399 106.0
WLSH2_k127_3297808_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 9.635e-204 654.0
WLSH2_k127_3297808_1 acyl-CoA dehydrogenase K09456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 624.0
WLSH2_k127_3297808_10 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000239 166.0
WLSH2_k127_3297808_11 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000001846 148.0
WLSH2_k127_3297808_12 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000005435 137.0
WLSH2_k127_3297808_13 - - - - 0.000000000000000000000000008334 120.0
WLSH2_k127_3297808_15 AhpC/TSA antioxidant enzyme - - - 0.00000000000000000001041 102.0
WLSH2_k127_3297808_16 Dehydrogenase reductase SDR family member K11168 - - 0.0000000000000000002201 98.0
WLSH2_k127_3297808_17 PFAM FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.0000002883 58.0
WLSH2_k127_3297808_18 Histidine kinase A domain protein - - - 0.00001148 53.0
WLSH2_k127_3297808_2 GMP synthase C terminal domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 507.0
WLSH2_k127_3297808_3 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 483.0
WLSH2_k127_3297808_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 477.0
WLSH2_k127_3297808_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 437.0
WLSH2_k127_3297808_6 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 341.0
WLSH2_k127_3297808_7 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000033 222.0
WLSH2_k127_3297808_8 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000003086 168.0
WLSH2_k127_3297808_9 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000008079 165.0
WLSH2_k127_3357620_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.165e-297 929.0
WLSH2_k127_3357620_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 546.0
WLSH2_k127_3357620_10 PFAM Heavy metal transport detoxification protein - - - 0.00000000000000000000906 93.0
WLSH2_k127_3357620_11 Transcriptional regulator - - - 0.00000000000000000001357 96.0
WLSH2_k127_3357620_12 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000002344 91.0
WLSH2_k127_3357620_13 DNA-binding transcription factor activity K15973 - - 0.0000004166 57.0
WLSH2_k127_3357620_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 469.0
WLSH2_k127_3357620_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 360.0
WLSH2_k127_3357620_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 327.0
WLSH2_k127_3357620_5 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 317.0
WLSH2_k127_3357620_6 PFAM transferase hexapeptide repeat containing protein K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000008793 265.0
WLSH2_k127_3357620_7 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.00000000000000000000000000000000000000000000000000000000000006172 229.0
WLSH2_k127_3357620_8 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000002778 216.0
WLSH2_k127_3357620_9 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000005854 107.0
WLSH2_k127_3425300_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 611.0
WLSH2_k127_3425300_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000004214 149.0
WLSH2_k127_3445182_0 CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 368.0
WLSH2_k127_3445182_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 308.0
WLSH2_k127_3445182_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004704 282.0
WLSH2_k127_3445182_3 COG0625 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000948 277.0
WLSH2_k127_3445182_4 PFAM outer membrane efflux protein - - - 0.0000000000000000000000000000000000000122 160.0
WLSH2_k127_3445182_5 PFAM CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000003063 134.0
WLSH2_k127_3445182_6 HEPN domain - - - 0.00000000000000005221 90.0
WLSH2_k127_3445182_7 nucleotidyltransferase activity - - - 0.000000001401 63.0
WLSH2_k127_34509_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 337.0
WLSH2_k127_34509_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000001423 230.0
WLSH2_k127_34509_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000003218 175.0
WLSH2_k127_34509_3 Pectinacetylesterase - - - 0.0000000000000000000000000000000000000000005655 179.0
WLSH2_k127_34509_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000003612 147.0
WLSH2_k127_34509_5 Enoyl- acyl-carrier-protein reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000114 87.0
WLSH2_k127_34509_6 PFAM Lytic transglycosylase catalytic K18691 - - 0.000008092 57.0
WLSH2_k127_3466064_0 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000321 286.0
WLSH2_k127_3466064_1 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 266.0
WLSH2_k127_3466064_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000006981 168.0
WLSH2_k127_3466064_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000005988 132.0
WLSH2_k127_3479120_0 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K19270 - 3.1.3.23 0.000000000000000000000000000000000000000000000000000000000000177 223.0
WLSH2_k127_3479120_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000002081 199.0
WLSH2_k127_3479120_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000002744 154.0
WLSH2_k127_3479120_3 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.000000000000000000000000000000001742 141.0
WLSH2_k127_3479120_4 Protein of unknown function (DUF1573) - - - 0.00000005619 61.0
WLSH2_k127_3479120_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0006667 44.0
WLSH2_k127_3498071_0 PFAM nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 527.0
WLSH2_k127_3498071_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 417.0
WLSH2_k127_3498071_2 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 421.0
WLSH2_k127_3498071_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 404.0
WLSH2_k127_3498071_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 325.0
WLSH2_k127_3498071_5 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 301.0
WLSH2_k127_3498071_6 COG0281 Malic enzyme K00029 - 1.1.1.40 0.00001221 48.0
WLSH2_k127_3510367_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 325.0
WLSH2_k127_3510367_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001453 241.0
WLSH2_k127_3523717_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K07516 - 1.1.1.35 2.492e-268 842.0
WLSH2_k127_3523717_1 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 449.0
WLSH2_k127_3523717_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 415.0
WLSH2_k127_3523717_3 xylulokinase activity K00879,K11216 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006004,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008737,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046372,GO:0046835,GO:0071704,GO:1901575 2.7.1.189,2.7.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000009166 280.0
WLSH2_k127_3523717_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.0000000000000000000000000000000000000000000000000000000000004337 224.0
WLSH2_k127_3523717_5 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000006647 214.0
WLSH2_k127_3523717_6 - K01865 - 5.4.4.1 0.000000000000000000000000000000000006218 141.0
WLSH2_k127_3523717_7 Bacterial regulatory proteins, tetR family - - - 0.000000000001136 76.0
WLSH2_k127_3547641_1 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 433.0
WLSH2_k127_3547641_2 membrane protein involved in D-alanine export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 389.0
WLSH2_k127_3547641_3 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003129 278.0
WLSH2_k127_3547641_4 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000003949 227.0
WLSH2_k127_3547641_5 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000116 167.0
WLSH2_k127_3547641_6 - - - - 0.0000000000000000000000000001215 131.0
WLSH2_k127_3547641_7 - - - - 0.00000000000000000000000003648 120.0
WLSH2_k127_3547641_8 Methyltransferase type 11 - - - 0.000000000000000000000001208 113.0
WLSH2_k127_3547641_9 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000008175 69.0
WLSH2_k127_3567634_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 378.0
WLSH2_k127_3567634_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002644 276.0
WLSH2_k127_3567634_2 PFAM CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003755 261.0
WLSH2_k127_3567634_3 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006721 255.0
WLSH2_k127_3567634_4 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000000001178 213.0
WLSH2_k127_3567634_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000007336 84.0
WLSH2_k127_3576066_0 helicase K03657 - 3.6.4.12 1.613e-207 670.0
WLSH2_k127_3576066_1 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 537.0
WLSH2_k127_3576066_10 Hemolysin-type calcium-binding repeat (2 copies) K01406 - 3.4.24.40 0.0007787 50.0
WLSH2_k127_3576066_2 Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 492.0
WLSH2_k127_3576066_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000005085 267.0
WLSH2_k127_3576066_4 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000004674 251.0
WLSH2_k127_3576066_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000006464 201.0
WLSH2_k127_3576066_6 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000005766 184.0
WLSH2_k127_3576066_7 transcriptional regulator K09017 - - 0.0000000000000001958 87.0
WLSH2_k127_3576066_9 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000002332 52.0
WLSH2_k127_3600355_0 PFAM acyl-CoA dehydrogenase domain protein K00255,K11731 - 1.3.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 381.0
WLSH2_k127_3600355_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 389.0
WLSH2_k127_3600355_2 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003754 276.0
WLSH2_k127_3600355_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000001971 176.0
WLSH2_k127_3600355_4 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000154 163.0
WLSH2_k127_3600355_5 Methyltransferase - - - 0.000000000000000000000000000000002063 139.0
WLSH2_k127_3600355_6 Thioesterase superfamily - - - 0.00000000000000000000000000002566 126.0
WLSH2_k127_3600355_7 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000009902 120.0
WLSH2_k127_3600355_8 Putative citrate transport - - - 0.0000000000000003793 83.0
WLSH2_k127_3600355_9 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000001393 64.0
WLSH2_k127_3667482_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001844 270.0
WLSH2_k127_3667482_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000003076 255.0
WLSH2_k127_3667482_2 PFAM Phosphate-selective porin O K07221 - - 0.000000000000000000000000000000000000000000000000000000004648 219.0
WLSH2_k127_3667482_3 PIN domain - - - 0.000000000000000000000000001961 116.0
WLSH2_k127_3667482_4 Adenylate cyclase - - - 0.00000000000000000000000001531 115.0
WLSH2_k127_3667482_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000004809 71.0
WLSH2_k127_3667482_6 Oxidoreductase - - - 0.000000005924 63.0
WLSH2_k127_3675234_0 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 370.0
WLSH2_k127_3675234_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000002117 243.0
WLSH2_k127_3675234_2 homoserine kinase activity K02204 - 2.7.1.39 0.000000000000000000000000000000000002417 152.0
WLSH2_k127_3675234_3 Evidence 2b Function of strongly homologous gene - - - 0.00000000001872 67.0
WLSH2_k127_3675234_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0001119 52.0
WLSH2_k127_371155_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 551.0
WLSH2_k127_371155_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000001561 112.0
WLSH2_k127_371155_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000005376 107.0
WLSH2_k127_371155_3 DDE domain K07498 - - 0.0000000000000000000000326 108.0
WLSH2_k127_371155_5 - - - - 0.00000001073 57.0
WLSH2_k127_383358_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 336.0
WLSH2_k127_383358_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 316.0
WLSH2_k127_383358_11 nuclease activity K18828 - - 0.00000000000000002337 90.0
WLSH2_k127_383358_12 AsmA family K07289 - - 0.000000000001819 80.0
WLSH2_k127_383358_13 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000133 72.0
WLSH2_k127_383358_14 isoprenylcysteine carboxyl methyltransferase - - - 0.0000002958 60.0
WLSH2_k127_383358_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 314.0
WLSH2_k127_383358_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001614 283.0
WLSH2_k127_383358_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003821 252.0
WLSH2_k127_383358_5 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000004933 243.0
WLSH2_k127_383358_6 Domain of unknown function (DUF3473) - - - 0.000000000000000000000000000000000000000000000000000008733 201.0
WLSH2_k127_383358_7 domain protein K02674,K07004 - - 0.0000000000000000000000000000000000000000001799 181.0
WLSH2_k127_383358_8 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.00000000000000000000000000000000000000009304 168.0
WLSH2_k127_383358_9 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000239 153.0
WLSH2_k127_4045473_0 chlorophyll binding K16191,K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008607 294.0
WLSH2_k127_4045473_1 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000003542 142.0
WLSH2_k127_4045473_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000002157 139.0
WLSH2_k127_4045473_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000005354 106.0
WLSH2_k127_4045473_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000000000006281 72.0
WLSH2_k127_4045473_5 - K03561,K12287 - - 0.0003755 54.0
WLSH2_k127_4139905_0 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 546.0
WLSH2_k127_4139905_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 292.0
WLSH2_k127_4139905_2 methylamine metabolic process K15977 - - 0.0000000000000000000000000009502 116.0
WLSH2_k127_4139905_3 PKD domain containing protein - - - 0.0000000000000000000000001277 124.0
WLSH2_k127_4139905_4 PIN domain - - - 0.00000000000000000001379 98.0
WLSH2_k127_4139905_5 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000000009988 95.0
WLSH2_k127_4139905_6 fructose-1,6-bisphosphatase K02446 - 3.1.3.11 0.00000784 59.0
WLSH2_k127_415406_0 Belongs to the thiolase family K07550 - - 1.725e-214 677.0
WLSH2_k127_415406_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 486.0
WLSH2_k127_415406_10 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007897 253.0
WLSH2_k127_415406_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001232 250.0
WLSH2_k127_415406_12 belongs to the aldehyde dehydrogenase family K03400 - 1.2.1.50 0.0000000000000000000000000000000000000000000000000000000000009636 228.0
WLSH2_k127_415406_13 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000004854 214.0
WLSH2_k127_415406_14 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000004024 199.0
WLSH2_k127_415406_15 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000002144 151.0
WLSH2_k127_415406_16 Domains HisKA, HATPase_c - - - 0.000000000000000000000000000000000000003025 156.0
WLSH2_k127_415406_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.00000000000000000000000000000000000001051 148.0
WLSH2_k127_415406_18 diguanylate cyclase - - - 0.0000000000000000001554 102.0
WLSH2_k127_415406_19 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000004771 82.0
WLSH2_k127_415406_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 449.0
WLSH2_k127_415406_20 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000001071 73.0
WLSH2_k127_415406_21 Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000008134 70.0
WLSH2_k127_415406_22 serine threonine protein phosphatase K04460 GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0023052,GO:0036211,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 3.1.3.16 0.0008038 46.0
WLSH2_k127_415406_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 416.0
WLSH2_k127_415406_4 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 415.0
WLSH2_k127_415406_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 392.0
WLSH2_k127_415406_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 383.0
WLSH2_k127_415406_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 362.0
WLSH2_k127_415406_8 COG0183 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 349.0
WLSH2_k127_415406_9 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002724 258.0
WLSH2_k127_4184473_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 2.422e-229 721.0
WLSH2_k127_4184473_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.074e-213 676.0
WLSH2_k127_4184473_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007173 602.0
WLSH2_k127_4184473_3 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 377.0
WLSH2_k127_4184473_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 310.0
WLSH2_k127_4184473_5 PFAM UBA THIF-type NAD FAD binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004871 241.0
WLSH2_k127_4184473_6 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000001511 163.0
WLSH2_k127_4184473_7 HNH nucleases - - - 0.00000000000000000000000000000000000002145 146.0
WLSH2_k127_4184473_8 Iron-containing alcohol dehydrogenase K00001,K04072 - 1.1.1.1,1.2.1.10 0.000000000000000072 84.0
WLSH2_k127_4208443_0 hydrolase activity, hydrolyzing O-glycosyl compounds K16147 - 2.4.99.16 3.953e-264 832.0
WLSH2_k127_4208443_1 6-phosphofructokinase activity K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 548.0
WLSH2_k127_4208443_10 PFAM Nickel transport complex, NikM subunit, transmembrane K10094 - - 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
WLSH2_k127_4208443_11 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000007704 241.0
WLSH2_k127_4208443_12 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000007302 206.0
WLSH2_k127_4208443_13 Biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000129 211.0
WLSH2_k127_4208443_14 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.0000000000000000000000000000000007985 137.0
WLSH2_k127_4208443_15 EXOIII K02342 - 2.7.7.7 0.00000000000000000000000001457 118.0
WLSH2_k127_4208443_16 - - - - 0.00000000000000004007 83.0
WLSH2_k127_4208443_17 Global regulator protein family K03563 - - 0.000001283 53.0
WLSH2_k127_4208443_2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 501.0
WLSH2_k127_4208443_3 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 421.0
WLSH2_k127_4208443_4 Protein of unknown function (DUF2804) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 364.0
WLSH2_k127_4208443_5 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 343.0
WLSH2_k127_4208443_6 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 333.0
WLSH2_k127_4208443_7 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 302.0
WLSH2_k127_4208443_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003304 277.0
WLSH2_k127_4208443_9 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005366 269.0
WLSH2_k127_4230693_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 347.0
WLSH2_k127_4230693_1 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 344.0
WLSH2_k127_4230693_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000005413 242.0
WLSH2_k127_4230693_3 dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000009544 235.0
WLSH2_k127_4230693_4 - - - - 0.00000000000000000000000000005473 120.0
WLSH2_k127_4230693_5 - - - - 0.000000001351 61.0
WLSH2_k127_4250498_0 reductase alpha subunit K00394 - 1.8.99.2 1e-323 998.0
WLSH2_k127_4250498_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 5.183e-237 763.0
WLSH2_k127_4250498_10 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000004948 189.0
WLSH2_k127_4250498_11 Ogr/Delta-like zinc finger - - - 0.00000000000000003622 87.0
WLSH2_k127_4250498_2 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 592.0
WLSH2_k127_4250498_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304 610.0
WLSH2_k127_4250498_4 PFAM fumarate reductase succinate dehydrogenase flavoprotein K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 406.0
WLSH2_k127_4250498_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 314.0
WLSH2_k127_4250498_6 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane K08265,K16887 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001696 262.0
WLSH2_k127_4250498_7 reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000005866 239.0
WLSH2_k127_4250498_8 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000002854 214.0
WLSH2_k127_4250498_9 PFAM Uncharacterised protein family (UPF0153) K18475 - - 0.00000000000000000000000000000000000000000000000000000006082 212.0
WLSH2_k127_4253920_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.307e-221 703.0
WLSH2_k127_4253920_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 456.0
WLSH2_k127_4253920_10 addiction module antidote protein, CC2985 family K07746 - - 0.000000000005396 69.0
WLSH2_k127_4253920_11 Belongs to the glycosyl hydrolase 43 family K06113 - 3.2.1.99 0.00000007776 64.0
WLSH2_k127_4253920_12 Plasmid stabilization system K19092 - - 0.0000002078 56.0
WLSH2_k127_4253920_13 Domain of unknown function (DUF4911) - - - 0.0000143 51.0
WLSH2_k127_4253920_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 305.0
WLSH2_k127_4253920_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000004064 198.0
WLSH2_k127_4253920_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000002335 186.0
WLSH2_k127_4253920_5 6-pyruvoyl tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000005864 155.0
WLSH2_k127_4253920_7 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0000000000000000004283 88.0
WLSH2_k127_4253920_8 addiction module antidote protein K07746 - - 0.000000000000000001038 88.0
WLSH2_k127_4253920_9 nucleotidyltransferase activity - - - 0.0000000000004809 71.0
WLSH2_k127_4256907_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 484.0
WLSH2_k127_4256907_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000008464 207.0
WLSH2_k127_4256907_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000003178 153.0
WLSH2_k127_4256907_3 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000005517 130.0
WLSH2_k127_4256907_4 - - - - 0.0000001214 55.0
WLSH2_k127_4278138_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 392.0
WLSH2_k127_4278138_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000001333 254.0
WLSH2_k127_4278138_2 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.00000000000000000000000000000000000000000000000000000000002012 209.0
WLSH2_k127_4287014_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 366.0
WLSH2_k127_4287014_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000003237 231.0
WLSH2_k127_4287014_2 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000543 113.0
WLSH2_k127_4287014_3 - - - - 0.0000000000000000000001027 104.0
WLSH2_k127_4287014_4 RNA-binding protein - - - 0.00000000000000004951 84.0
WLSH2_k127_4287014_5 - - - - 0.0000000000009921 78.0
WLSH2_k127_4333551_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 342.0
WLSH2_k127_4333551_1 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000005438 214.0
WLSH2_k127_4333551_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000001666 168.0
WLSH2_k127_4333551_3 - - - - 0.00000000000000000000000339 113.0
WLSH2_k127_4333551_4 CBS domain containing protein - - - 0.00000000001468 68.0
WLSH2_k127_4343706_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 522.0
WLSH2_k127_4343706_1 PFAM AMP-dependent synthetase and ligase K00666,K01897,K12508 - 6.2.1.3,6.2.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 485.0
WLSH2_k127_4343706_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004928 234.0
WLSH2_k127_4343706_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000000005152 193.0
WLSH2_k127_4343706_12 TIGRFAM HAD-superfamily hydrolase, subfamily IIA K01101 - 3.1.3.41 0.00000000000000000000000000000000000000000000000003653 188.0
WLSH2_k127_4343706_13 - - - - 0.0000000000000000000000000002649 115.0
WLSH2_k127_4343706_14 Hydrogenase expression formation protein K04653 - - 0.0000000000000000001343 90.0
WLSH2_k127_4343706_15 4Fe-4S dicluster domain - - - 0.0000124 56.0
WLSH2_k127_4343706_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 442.0
WLSH2_k127_4343706_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 433.0
WLSH2_k127_4343706_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 426.0
WLSH2_k127_4343706_5 Dehydrogenase E1 component K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 355.0
WLSH2_k127_4343706_6 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 345.0
WLSH2_k127_4343706_7 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002001 272.0
WLSH2_k127_4343706_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000005787 262.0
WLSH2_k127_4343706_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 236.0
WLSH2_k127_4365431_0 CoA binding domain K01905,K22224 - 6.2.1.13 1.029e-242 768.0
WLSH2_k127_4365431_1 Aminotransferase K00813 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 520.0
WLSH2_k127_4365431_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 477.0
WLSH2_k127_4365431_3 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000001302 119.0
WLSH2_k127_4365431_4 Domain of unknown function (DUF4912) K09942 - - 0.00000000000000000000001196 114.0
WLSH2_k127_442473_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 584.0
WLSH2_k127_442473_1 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 439.0
WLSH2_k127_442473_2 Quinolinate synthetase A protein K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 291.0
WLSH2_k127_442473_3 Domain of unknown function (DUF1730) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002037 286.0
WLSH2_k127_442473_4 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001201 263.0
WLSH2_k127_442473_5 Sulfotransferase domain - - - 0.00000000000000000000000000000006931 137.0
WLSH2_k127_442473_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000576 125.0
WLSH2_k127_442473_7 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000006926 68.0
WLSH2_k127_449338_0 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 344.0
WLSH2_k127_449338_1 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002326 272.0
WLSH2_k127_449338_2 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000003446 219.0
WLSH2_k127_449338_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000002097 221.0
WLSH2_k127_449338_4 TOBE domain K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000006522 179.0
WLSH2_k127_449338_5 mRNA binding - - - 0.00000000000000000000001933 101.0
WLSH2_k127_449338_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000003941 78.0
WLSH2_k127_449338_7 Sterol carrier protein - - - 0.00000000000002041 78.0
WLSH2_k127_4598958_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001509 277.0
WLSH2_k127_4598958_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000015 213.0
WLSH2_k127_4598958_2 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000000000000000000000000001736 182.0
WLSH2_k127_4598958_3 High confidence in function and specificity - - - 0.0000000000000000000000000000000000000002416 164.0
WLSH2_k127_4598958_4 protein conserved in bacteria K09778 - - 0.000000000000000000000001223 120.0
WLSH2_k127_4598958_5 Belongs to the UPF0434 family K09791 - - 0.000000000000000000005351 93.0
WLSH2_k127_465386_0 Domain of unknown function (DUF4215) - - - 0.00000000000000000000000000000000009136 149.0
WLSH2_k127_465386_1 Domain of unknown function (DUF4215) - - - 0.00000000000006981 85.0
WLSH2_k127_4656043_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000001342 218.0
WLSH2_k127_4656043_1 PIN domain - - - 0.00000000000000000000000000000000000000000000000001323 184.0
WLSH2_k127_4656043_2 PIN domain - - - 0.0000000000000000000000000000000000005125 144.0
WLSH2_k127_4656043_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000005571 89.0
WLSH2_k127_4656043_4 - - - - 0.00000000004313 68.0
WLSH2_k127_4656043_5 Transfers the fatty acyl group on membrane lipoproteins - - - 0.00007421 56.0
WLSH2_k127_468262_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 356.0
WLSH2_k127_468262_1 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000009307 237.0
WLSH2_k127_468262_2 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000007673 122.0
WLSH2_k127_468262_3 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000576 109.0
WLSH2_k127_468262_4 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001844 88.0
WLSH2_k127_468262_5 Colicin V production protein K03558 - - 0.00000000004718 70.0
WLSH2_k127_4750619_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 546.0
WLSH2_k127_4750619_1 PFAM Domain of unkown function DUF1786 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 462.0
WLSH2_k127_4750619_10 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000001672 139.0
WLSH2_k127_4750619_11 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.000000000000000000000000000000002144 135.0
WLSH2_k127_4750619_12 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000003729 126.0
WLSH2_k127_4750619_13 light absorption K01822,K21972 - 5.3.3.1 0.0000000000000000000000000006627 125.0
WLSH2_k127_4750619_14 AhpC/TSA antioxidant enzyme - - - 0.000000000000000000000004187 117.0
WLSH2_k127_4750619_15 Bacterial regulatory proteins, tetR family - - - 0.0000000000000003125 78.0
WLSH2_k127_4750619_16 Phosphate acyltransferases - - - 0.000000000000009422 78.0
WLSH2_k127_4750619_17 Protein of unknown function (DUF2892) - - - 0.0000000000001519 77.0
WLSH2_k127_4750619_18 cysteine-tRNA ligase activity - - - 0.000000000009521 66.0
WLSH2_k127_4750619_19 - - - - 0.000000000957 69.0
WLSH2_k127_4750619_2 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 426.0
WLSH2_k127_4750619_3 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 379.0
WLSH2_k127_4750619_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386,K20011 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005693 276.0
WLSH2_k127_4750619_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002205 267.0
WLSH2_k127_4750619_6 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000001839 240.0
WLSH2_k127_4750619_7 Outer Membrane Lipoprotein K03098 - - 0.000000000000000000000000000000000000000000000000000000008 204.0
WLSH2_k127_4750619_8 YceI-like domain - - - 0.000000000000000000000000000000000000000000004198 177.0
WLSH2_k127_4750619_9 TspO MBR family protein K05770 - - 0.0000000000000000000000000000000000000002787 154.0
WLSH2_k127_4819428_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.664e-291 903.0
WLSH2_k127_4819428_1 acyl-CoA dehydrogenase - - - 2.265e-286 888.0
WLSH2_k127_4819428_10 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000003919 116.0
WLSH2_k127_4819428_11 Pfam:DUF2029 - - - 0.0000000000000000000001249 112.0
WLSH2_k127_4819428_12 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000008304 68.0
WLSH2_k127_4819428_13 Glycosyl transferase, family 2 - - - 0.0000000013 67.0
WLSH2_k127_4819428_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 444.0
WLSH2_k127_4819428_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 426.0
WLSH2_k127_4819428_4 Sir2 family K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004047 281.0
WLSH2_k127_4819428_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000006711 249.0
WLSH2_k127_4819428_6 Zinc-binding dehydrogenase K00001,K19745 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003961 239.0
WLSH2_k127_4819428_7 Belongs to the enoyl-CoA hydratase isomerase family K01715,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000000000001318 187.0
WLSH2_k127_4819428_8 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000006354 126.0
WLSH2_k127_4819428_9 - - - - 0.0000000000000000000000000002607 118.0
WLSH2_k127_4967274_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1187.0
WLSH2_k127_4967274_1 Heat shock 70 kDa protein K04043 - - 1.618e-308 955.0
WLSH2_k127_4967274_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000002523 138.0
WLSH2_k127_4967274_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 583.0
WLSH2_k127_4967274_3 PFAM Type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 544.0
WLSH2_k127_4967274_4 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 464.0
WLSH2_k127_4967274_5 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 310.0
WLSH2_k127_4967274_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000005666 238.0
WLSH2_k127_4967274_7 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001269 235.0
WLSH2_k127_4967274_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000003073 152.0
WLSH2_k127_4967274_9 ACT domain - - - 0.0000000000000000000000000000000002887 138.0
WLSH2_k127_498425_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001176 277.0
WLSH2_k127_498425_1 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000125 269.0
WLSH2_k127_498425_2 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004366 247.0
WLSH2_k127_498425_3 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000004368 216.0
WLSH2_k127_498425_4 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000007553 214.0
WLSH2_k127_498425_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000007474 171.0
WLSH2_k127_498425_6 - - - - 0.0000000000000002932 90.0
WLSH2_k127_498425_7 Protein of unknown function (DUF3604) - - - 0.00000000000005081 83.0
WLSH2_k127_498425_8 Glycine-zipper domain - - - 0.0000001712 53.0
WLSH2_k127_4986734_0 synthase K00705,K06044 GO:0000272,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009251,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0030978,GO:0030980,GO:0034637,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0047470,GO:0071704,GO:1901575,GO:1901576 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 492.0
WLSH2_k127_4986734_1 domain protein K02674,K07004 - - 0.00000000000000001866 82.0
WLSH2_k127_5023332_0 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000004965 250.0
WLSH2_k127_5023332_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000001325 239.0
WLSH2_k127_5023332_2 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000007189 211.0
WLSH2_k127_5023332_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000001212 206.0
WLSH2_k127_5023332_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000003175 144.0
WLSH2_k127_5023332_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000001337 127.0
WLSH2_k127_5023332_6 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000001484 103.0
WLSH2_k127_5096062_0 PFAM HypF finger K04656 - - 2.369e-297 930.0
WLSH2_k127_5096062_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 7.598e-223 702.0
WLSH2_k127_5096062_10 Protein of unknown function (DUF2384) - - - 0.00000000000000000000008167 103.0
WLSH2_k127_5096062_12 - - - - 0.0000000000000000003344 89.0
WLSH2_k127_5096062_13 PFAM HEPN domain K09132 - - 0.000000000001874 74.0
WLSH2_k127_5096062_14 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000001453 63.0
WLSH2_k127_5096062_15 PFAM Glycoside hydrolase 15-related - - - 0.0000002544 57.0
WLSH2_k127_5096062_16 Methyltransferase domain - - - 0.000001661 55.0
WLSH2_k127_5096062_17 CopG antitoxin of type II toxin-antitoxin system - - - 0.00001565 51.0
WLSH2_k127_5096062_2 synthetase K00666,K18688 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576 6.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 613.0
WLSH2_k127_5096062_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 516.0
WLSH2_k127_5096062_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000002794 224.0
WLSH2_k127_5096062_5 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000612 203.0
WLSH2_k127_5096062_6 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000001338 185.0
WLSH2_k127_5096062_7 RES - - - 0.00000000000000000000000000000004207 130.0
WLSH2_k127_5096062_9 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000001069 104.0
WLSH2_k127_515358_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1318.0
WLSH2_k127_515358_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 4.563e-270 839.0
WLSH2_k127_515358_2 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001146 255.0
WLSH2_k127_515358_3 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000004233 134.0
WLSH2_k127_515358_4 Biotin-lipoyl like - - - 0.00000000000332 70.0
WLSH2_k127_518277_0 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 400.0
WLSH2_k127_518277_1 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 323.0
WLSH2_k127_518277_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009774 263.0
WLSH2_k127_518277_3 (Lipo)protein K04754 - - 0.0000000000000000000000000000000000000000009157 167.0
WLSH2_k127_518277_4 MlaC protein K07323 - - 0.000000000000000000000000000000000000002339 159.0
WLSH2_k127_518277_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K10700,K17050 - 1.17.99.2,1.8.5.3 0.000001145 51.0
WLSH2_k127_5241727_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 387.0
WLSH2_k127_5241727_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 323.0
WLSH2_k127_5241727_2 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 317.0
WLSH2_k127_5241727_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001498 281.0
WLSH2_k127_527546_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 1.073e-318 990.0
WLSH2_k127_527546_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 552.0
WLSH2_k127_527546_10 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007524 266.0
WLSH2_k127_527546_11 Anion-transporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006329 243.0
WLSH2_k127_527546_12 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001163 217.0
WLSH2_k127_527546_13 oxidoreductase activity, acting on CH-OH group of donors K03520,K09386 - 1.2.5.3 0.000000000000000000000000000000000000000006654 160.0
WLSH2_k127_527546_14 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000001418 142.0
WLSH2_k127_527546_15 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 0.000000000000000000000000000000001374 139.0
WLSH2_k127_527546_16 SpoVT AbrB like domain - - - 0.00000000000000002255 88.0
WLSH2_k127_527546_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 510.0
WLSH2_k127_527546_3 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 465.0
WLSH2_k127_527546_4 formyl-CoA transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 458.0
WLSH2_k127_527546_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 368.0
WLSH2_k127_527546_6 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 314.0
WLSH2_k127_527546_7 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 309.0
WLSH2_k127_527546_8 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 301.0
WLSH2_k127_527546_9 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 276.0
WLSH2_k127_5275697_0 GAD domain K01876 - 6.1.1.12 9.398e-212 673.0
WLSH2_k127_5275697_1 Protein export membrane protein K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 489.0
WLSH2_k127_5275697_10 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000883 85.0
WLSH2_k127_5275697_11 Zinc dependent phospholipase C - - - 0.000000000000000273 85.0
WLSH2_k127_5275697_12 DNA excision K02806 - - 0.000007971 50.0
WLSH2_k127_5275697_2 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 470.0
WLSH2_k127_5275697_3 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 405.0
WLSH2_k127_5275697_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 389.0
WLSH2_k127_5275697_5 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 321.0
WLSH2_k127_5275697_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 328.0
WLSH2_k127_5275697_7 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 326.0
WLSH2_k127_5275697_8 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
WLSH2_k127_5275697_9 Methyltransferase domain K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000000000000000001073 168.0
WLSH2_k127_5326833_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050789,GO:0050793,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 2.049e-246 771.0
WLSH2_k127_5326833_1 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.43e-229 732.0
WLSH2_k127_5326833_10 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000003381 126.0
WLSH2_k127_5326833_11 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000004837 123.0
WLSH2_k127_5326833_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 405.0
WLSH2_k127_5326833_3 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 378.0
WLSH2_k127_5326833_4 Histidine kinase A domain protein K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 346.0
WLSH2_k127_5326833_5 Belongs to the thiolase family K02615 - 2.3.1.174,2.3.1.223 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000848 292.0
WLSH2_k127_5326833_6 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000389 259.0
WLSH2_k127_5326833_7 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.00000000000000000000000000000000000000000000000000000002432 209.0
WLSH2_k127_5326833_8 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000002538 166.0
WLSH2_k127_5326833_9 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.000000000000000000000000000000000288 137.0
WLSH2_k127_5345020_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 449.0
WLSH2_k127_5345020_1 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000001672 264.0
WLSH2_k127_5345020_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000001203 250.0
WLSH2_k127_5345020_3 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000988 227.0
WLSH2_k127_5345020_4 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.0000000000000000000000000000000000006106 153.0
WLSH2_k127_5345020_5 proteolysis K21140,K21147 - 2.7.7.80,2.8.1.11,3.13.1.6 0.000000000000000000000000000000001696 135.0
WLSH2_k127_5345020_6 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.0000000000000000000009447 106.0
WLSH2_k127_5345020_7 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000001494 64.0
WLSH2_k127_535081_0 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000006795 221.0
WLSH2_k127_535081_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000008358 218.0
WLSH2_k127_535081_2 leucine- rich repeat protein - - - 0.000000002268 67.0
WLSH2_k127_5364453_0 Sodium:sulfate symporter transmembrane region - - - 5.566e-235 745.0
WLSH2_k127_5364453_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 550.0
WLSH2_k127_5364453_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 422.0
WLSH2_k127_5364453_3 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000001459 211.0
WLSH2_k127_5364453_4 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000004559 201.0
WLSH2_k127_5364453_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000005609 159.0
WLSH2_k127_5364453_6 PFAM CBS domain - - - 0.00000000000000000000000000000000000022 147.0
WLSH2_k127_5385076_0 PFAM Flp Fap pilin component K02651 - - 0.000008774 50.0
WLSH2_k127_5400579_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 2.786e-232 725.0
WLSH2_k127_5400579_1 Belongs to the amidase family K01426 - 3.5.1.4 3.957e-201 635.0
WLSH2_k127_5400579_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000257 293.0
WLSH2_k127_5400579_11 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007143 282.0
WLSH2_k127_5400579_12 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000002843 201.0
WLSH2_k127_5400579_13 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000004969 195.0
WLSH2_k127_5400579_14 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000666 177.0
WLSH2_k127_5400579_15 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000007351 151.0
WLSH2_k127_5400579_16 SnoaL-like domain - - - 0.00000000000000000000000000000000001509 140.0
WLSH2_k127_5400579_17 Phytoene dehydrogenase - - - 0.000000000000000000000000000000005102 147.0
WLSH2_k127_5400579_18 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000000000000001051 126.0
WLSH2_k127_5400579_19 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000003396 119.0
WLSH2_k127_5400579_2 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 563.0
WLSH2_k127_5400579_20 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000000000003249 116.0
WLSH2_k127_5400579_21 Cytochrome c3 - - - 0.00000000000000000000000004981 113.0
WLSH2_k127_5400579_22 Prokaryotic cytochrome b561 - - - 0.000000000000000000000001477 113.0
WLSH2_k127_5400579_23 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000006351 106.0
WLSH2_k127_5400579_24 NAD(P)-binding Rossmann-like domain - - - 0.000000000000001735 82.0
WLSH2_k127_5400579_25 Cytochrome C biogenesis protein K02200 - - 0.00000000002171 71.0
WLSH2_k127_5400579_26 PHP domain protein K07053 - 3.1.3.97 0.00000003045 62.0
WLSH2_k127_5400579_27 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000008048 57.0
WLSH2_k127_5400579_28 Haloacid dehalogenase-like hydrolase K07025 - - 0.000002895 52.0
WLSH2_k127_5400579_3 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 499.0
WLSH2_k127_5400579_4 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 432.0
WLSH2_k127_5400579_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 365.0
WLSH2_k127_5400579_6 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 353.0
WLSH2_k127_5400579_7 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 346.0
WLSH2_k127_5400579_8 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 297.0
WLSH2_k127_5400579_9 NADPH-hemoprotein reductase activity K00327,K00380 GO:0000166,GO:0003674,GO:0003824,GO:0003958,GO:0005488,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016651,GO:0016653,GO:0030587,GO:0032502,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0048856,GO:0050660,GO:0050661,GO:0050662,GO:0051703,GO:0051704,GO:0055114,GO:0090702,GO:0097159,GO:0097367,GO:0099120,GO:1901265,GO:1901363 1.6.2.4,1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 299.0
WLSH2_k127_5509831_0 Alpha-amylase domain K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 519.0
WLSH2_k127_5509831_1 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 428.0
WLSH2_k127_5509831_2 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003242 261.0
WLSH2_k127_5509831_3 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000005663 153.0
WLSH2_k127_5509831_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000001355 113.0
WLSH2_k127_5509831_5 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000002779 107.0
WLSH2_k127_5509831_6 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000001536 102.0
WLSH2_k127_5592397_1 Sulfatase - - - 0.000000000000000000415 93.0
WLSH2_k127_5605141_0 SMART alpha amylase, catalytic sub domain K01187,K05343 - 3.2.1.1,3.2.1.20,5.4.99.16 1.057e-222 693.0
WLSH2_k127_5605141_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700,K01236 - 2.4.1.18,3.2.1.141 5.852e-203 650.0
WLSH2_k127_5605141_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 353.0
WLSH2_k127_5605141_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002015 254.0
WLSH2_k127_5605141_4 - - - - 0.000000000000000000000000000000000505 134.0
WLSH2_k127_5605141_5 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000003466 89.0
WLSH2_k127_5605141_7 Bacterial extracellular solute-binding protein K02048 - - 0.000000009094 61.0
WLSH2_k127_5605141_8 Carbohydrate phosphorylase K00688,K00691 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.4.1.1,2.4.1.8 0.0000004936 61.0
WLSH2_k127_5605141_9 - - - - 0.0005502 47.0
WLSH2_k127_573040_0 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 360.0
WLSH2_k127_573040_1 PFAM ABC transporter related K02017,K15497 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 295.0
WLSH2_k127_573040_2 lactate metabolic process K00113,K21834 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000006464 248.0
WLSH2_k127_573040_3 ATPase-coupled sulfate transmembrane transporter activity K02018 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001829 166.0
WLSH2_k127_573040_4 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000001301 127.0
WLSH2_k127_573040_5 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000004241 121.0
WLSH2_k127_573040_6 Protein of unknown function (DUF2892) - - - 0.000000008755 60.0
WLSH2_k127_5749971_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 520.0
WLSH2_k127_5749971_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 401.0
WLSH2_k127_5749971_2 IMP dehydrogenase / GMP reductase domain K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 368.0
WLSH2_k127_5749971_3 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000000000000000000002916 169.0
WLSH2_k127_575576_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 538.0
WLSH2_k127_575576_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000007391 163.0
WLSH2_k127_575576_2 Response regulator receiver K11443 - - 0.0000000000000000000000000000001342 128.0
WLSH2_k127_575576_3 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000004235 108.0
WLSH2_k127_5796822_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 543.0
WLSH2_k127_5796822_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 458.0
WLSH2_k127_5796822_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001297 252.0
WLSH2_k127_5796822_3 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000001282 204.0
WLSH2_k127_5796822_4 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.00000000000000000000000000000000000000654 166.0
WLSH2_k127_5796822_5 alginic acid biosynthetic process K09483 - 4.2.1.118 0.0000000004196 72.0
WLSH2_k127_5888547_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 390.0
WLSH2_k127_5888547_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000689 273.0
WLSH2_k127_5888547_2 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000005894 194.0
WLSH2_k127_5888547_3 Uroporphyrinogen-III synthase HemD K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000003671 94.0
WLSH2_k127_5888547_4 PFAM extracellular solute-binding protein family 5 K02035 - - 0.000000725 55.0
WLSH2_k127_5890524_0 formate C-acetyltransferase glycine radical - - - 0.0 1228.0
WLSH2_k127_5890524_1 PhoQ Sensor - - - 5.236e-205 671.0
WLSH2_k127_5890524_10 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.000000000000000000000000000000002402 134.0
WLSH2_k127_5890524_11 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000002492 135.0
WLSH2_k127_5890524_12 MltA specific insert domain K08304 - - 0.0000000000000000000000000008322 121.0
WLSH2_k127_5890524_13 - - - - 0.00000000009722 66.0
WLSH2_k127_5890524_14 - - - - 0.00000001056 61.0
WLSH2_k127_5890524_2 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 616.0
WLSH2_k127_5890524_3 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 593.0
WLSH2_k127_5890524_4 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 482.0
WLSH2_k127_5890524_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 374.0
WLSH2_k127_5890524_6 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001548 284.0
WLSH2_k127_5890524_7 extracellular structure organization - GO:0003674,GO:0005198,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0010033,GO:0014070,GO:0016043,GO:0030198,GO:0030587,GO:0031012,GO:0031154,GO:0032502,GO:0042221,GO:0043062,GO:0044421,GO:0048856,GO:0050896,GO:0051703,GO:0051704,GO:0071840,GO:0080184,GO:0090702,GO:0099120,GO:1901700,GO:1902168,GO:1905395 - 0.0000000000000000000000000000000000000000000000256 193.0
WLSH2_k127_5890524_8 Tyrosine phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000001479 160.0
WLSH2_k127_5890524_9 Transcriptional regulator, GntR family K05799 - - 0.000000000000000000000000000000000001272 152.0
WLSH2_k127_5910096_0 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.088e-249 799.0
WLSH2_k127_5910096_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.862e-205 655.0
WLSH2_k127_5910096_10 Cytidylate kinase K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000002038 208.0
WLSH2_k127_5910096_11 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000001461 181.0
WLSH2_k127_5910096_12 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000001914 149.0
WLSH2_k127_5910096_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000007012 113.0
WLSH2_k127_5910096_14 PFAM response regulator receiver - - - 0.000000002917 60.0
WLSH2_k127_5910096_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 3.239e-203 664.0
WLSH2_k127_5910096_3 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 547.0
WLSH2_k127_5910096_4 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 334.0
WLSH2_k127_5910096_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 299.0
WLSH2_k127_5910096_6 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002013 291.0
WLSH2_k127_5910096_7 TIGRFAM tyrosine recombinase XerD K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005587 279.0
WLSH2_k127_5910096_8 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000002346 246.0
WLSH2_k127_5910096_9 signal peptide peptidase SppA K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000004552 236.0
WLSH2_k127_5922124_0 Extracellular solute-binding protein, family 5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 522.0
WLSH2_k127_5922124_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
WLSH2_k127_5922124_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 307.0
WLSH2_k127_5922124_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000001109 232.0
WLSH2_k127_5922124_4 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000001699 208.0
WLSH2_k127_5922124_5 methyltransferase activity - - - 0.00000000000000000000003951 105.0
WLSH2_k127_5922124_6 Protein of unknown function (DUF1302) - - - 0.00000000000000000001577 107.0
WLSH2_k127_5922124_7 metallopeptidase activity K06889 - - 0.00000000000007461 85.0
WLSH2_k127_6055318_0 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000000000000000000004076 155.0
WLSH2_k127_6055318_1 Integrase - - - 0.00000000000000000000000003064 120.0
WLSH2_k127_6055318_2 AraC-like ligand binding domain - - - 0.00000000000000000000000363 106.0
WLSH2_k127_6055318_3 Integrase - - - 0.0000000000000000003364 93.0
WLSH2_k127_6059290_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 605.0
WLSH2_k127_6059290_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00004,K00008,K05351,K08322 - 1.1.1.14,1.1.1.303,1.1.1.380,1.1.1.4,1.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000007117 261.0
WLSH2_k127_6059290_2 Arm DNA-binding domain K14059 - - 0.0000000000000000000000000000001173 138.0
WLSH2_k127_6059290_3 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000008804 126.0
WLSH2_k127_6059290_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000005589 90.0
WLSH2_k127_6087184_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.933e-257 811.0
WLSH2_k127_6087184_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.319e-200 642.0
WLSH2_k127_6087184_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000008983 234.0
WLSH2_k127_6087184_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000005381 132.0
WLSH2_k127_6087184_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000003876 104.0
WLSH2_k127_6087184_5 Protein conserved in bacteria K09764 - - 0.0000000000000000002499 91.0
WLSH2_k127_609003_0 formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1064.0
WLSH2_k127_609003_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 5.33e-259 813.0
WLSH2_k127_609003_10 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 372.0
WLSH2_k127_609003_11 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 364.0
WLSH2_k127_609003_12 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 325.0
WLSH2_k127_609003_13 Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 302.0
WLSH2_k127_609003_14 ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001513 269.0
WLSH2_k127_609003_15 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000004039 250.0
WLSH2_k127_609003_16 Pup-ligase protein K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119 0.000000000000000000000000000000000000000000000000000000000000001989 238.0
WLSH2_k127_609003_17 Pup-ligase protein K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00000000000000000000000000000000000000000000000000000002827 217.0
WLSH2_k127_609003_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000003333 179.0
WLSH2_k127_609003_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000009753 172.0
WLSH2_k127_609003_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 1.78e-218 698.0
WLSH2_k127_609003_20 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000005258 183.0
WLSH2_k127_609003_21 Enoyl-CoA hydratase/isomerase K01715,K08299 - 4.2.1.149,4.2.1.17 0.00000000000000000000000000000000000003692 155.0
WLSH2_k127_609003_22 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000009883 147.0
WLSH2_k127_609003_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000001428 126.0
WLSH2_k127_609003_24 D-aminopeptidase K16203 - - 0.00000000000000000000000329 112.0
WLSH2_k127_609003_25 HEPN domain - - - 0.000000000000000000000005083 105.0
WLSH2_k127_609003_26 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000447 107.0
WLSH2_k127_609003_27 Nucleotidyltransferase domain K07076 - - 0.000000000000000000007392 95.0
WLSH2_k127_609003_28 4-amino-4-deoxy-L-arabinose transferase and related - - - 0.00000000000000000005492 106.0
WLSH2_k127_609003_3 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 583.0
WLSH2_k127_609003_30 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000002548 81.0
WLSH2_k127_609003_31 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.00000000001125 66.0
WLSH2_k127_609003_32 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897,K12508 - 6.2.1.3,6.2.1.34 0.00000000001332 71.0
WLSH2_k127_609003_33 involved in molybdopterin and thiamine biosynthesis family 2 - - - 0.00000000008799 74.0
WLSH2_k127_609003_34 PFAM Mov34 MPN PAD-1 family - - - 0.00000000861 67.0
WLSH2_k127_609003_35 Ubiquitin-conjugating enzyme E2, catalytic domain homologues - - - 0.000000648 58.0
WLSH2_k127_609003_36 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000007389 48.0
WLSH2_k127_609003_4 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 557.0
WLSH2_k127_609003_5 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 541.0
WLSH2_k127_609003_6 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 517.0
WLSH2_k127_609003_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 485.0
WLSH2_k127_609003_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 389.0
WLSH2_k127_609003_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 380.0
WLSH2_k127_6114483_0 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 360.0
WLSH2_k127_6114483_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 356.0
WLSH2_k127_6114483_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 299.0
WLSH2_k127_6114483_3 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000005708 204.0
WLSH2_k127_6114483_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001102 182.0
WLSH2_k127_6114483_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000001935 138.0
WLSH2_k127_6114483_6 Protein of unknown function (DUF1778) - - - 0.00000000000000000000219 98.0
WLSH2_k127_6114483_7 Belongs to the 'phage' integrase family - - - 0.000000000000009981 78.0
WLSH2_k127_6120254_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 435.0
WLSH2_k127_6120254_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000591 129.0
WLSH2_k127_6120254_2 Las17-binding protein actin regulator - - - 0.00000000002975 68.0
WLSH2_k127_6121316_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.38e-202 650.0
WLSH2_k127_6121316_1 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008388 595.0
WLSH2_k127_6121316_2 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 422.0
WLSH2_k127_6121316_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 400.0
WLSH2_k127_6121316_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001617 241.0
WLSH2_k127_6121316_5 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000004651 216.0
WLSH2_k127_6121316_6 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000001572 126.0
WLSH2_k127_6121316_7 SAF K01685,K01708 - 4.2.1.42,4.2.1.7 0.00000000000000001128 86.0
WLSH2_k127_6161062_0 HflC and HflK could encode or regulate a protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 583.0
WLSH2_k127_6161062_1 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000002188 233.0
WLSH2_k127_6161062_2 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.0001238 49.0
WLSH2_k127_618587_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 422.0
WLSH2_k127_618587_1 glycosyl transferase, family 39 - - - 0.0000000000000000007532 91.0
WLSH2_k127_626986_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 6.311e-222 727.0
WLSH2_k127_626986_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000251 235.0
WLSH2_k127_626986_2 HTH-like domain K07497 - - 0.0000000000000004296 88.0
WLSH2_k127_626986_3 Alpha beta hydrolase - - - 0.000000000628 66.0
WLSH2_k127_6291808_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.038e-283 897.0
WLSH2_k127_6291808_1 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 499.0
WLSH2_k127_6291808_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000004956 222.0
WLSH2_k127_6291808_11 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000003813 186.0
WLSH2_k127_6291808_12 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000106 166.0
WLSH2_k127_6291808_13 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000006993 138.0
WLSH2_k127_6291808_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000000000000000000000000004955 130.0
WLSH2_k127_6291808_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000006222 121.0
WLSH2_k127_6291808_16 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000004903 80.0
WLSH2_k127_6291808_17 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0000000000000008155 90.0
WLSH2_k127_6291808_18 denitrification pathway - - - 0.000000001091 66.0
WLSH2_k127_6291808_19 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000471 64.0
WLSH2_k127_6291808_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 446.0
WLSH2_k127_6291808_20 - - - - 0.00008855 55.0
WLSH2_k127_6291808_21 Integrase - - - 0.0006046 44.0
WLSH2_k127_6291808_3 PCRF K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 414.0
WLSH2_k127_6291808_4 AAA domain K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 408.0
WLSH2_k127_6291808_5 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 398.0
WLSH2_k127_6291808_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 386.0
WLSH2_k127_6291808_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 375.0
WLSH2_k127_6291808_8 TIGRFAM competence damage-inducible protein CinA K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 316.0
WLSH2_k127_6291808_9 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005062 272.0
WLSH2_k127_635349_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 566.0
WLSH2_k127_635349_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 511.0
WLSH2_k127_635349_2 PFAM Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000663 261.0
WLSH2_k127_635349_3 Belongs to the MT-A70-like family - - - 0.00003934 46.0
WLSH2_k127_635349_4 Laminin G domain - - - 0.00004672 56.0
WLSH2_k127_6376270_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 537.0
WLSH2_k127_6376270_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000002517 225.0
WLSH2_k127_6376270_10 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000007637 131.0
WLSH2_k127_6376270_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000002878 123.0
WLSH2_k127_6376270_12 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000001763 115.0
WLSH2_k127_6376270_13 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000006805 129.0
WLSH2_k127_6376270_14 Methyltransferase type 11 Methyltransferase type 12 - - - 0.00000000000000000000000001121 121.0
WLSH2_k127_6376270_15 Integrase - - - 0.000000000000000000000518 101.0
WLSH2_k127_6376270_16 toxin-antitoxin pair type II binding - - - 0.000000000000000007927 89.0
WLSH2_k127_6376270_17 Thrombospondin type 3 repeat - - - 0.000000000002736 79.0
WLSH2_k127_6376270_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000002116 214.0
WLSH2_k127_6376270_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000004636 223.0
WLSH2_k127_6376270_4 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000001208 207.0
WLSH2_k127_6376270_5 Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000004313 185.0
WLSH2_k127_6376270_6 Sulfatase - - - 0.0000000000000000000000000000000000000000000266 186.0
WLSH2_k127_6376270_7 Methionine biosynthesis protein MetW K20444 - - 0.00000000000000000000000000000000000000007498 173.0
WLSH2_k127_6376270_8 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000006185 163.0
WLSH2_k127_6376270_9 nucleotidyltransferase activity K07075,K07076 - - 0.000000000000000000000000000000001445 135.0
WLSH2_k127_6394956_0 Belongs to the GPI family K01810 - 5.3.1.9 3.293e-260 814.0
WLSH2_k127_6394956_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 483.0
WLSH2_k127_6394956_10 Acetone carboxylase gamma K10856 - 6.4.1.6 0.0000000000001108 72.0
WLSH2_k127_6394956_2 PFAM acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 473.0
WLSH2_k127_6394956_3 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 447.0
WLSH2_k127_6394956_4 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 399.0
WLSH2_k127_6394956_5 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 372.0
WLSH2_k127_6394956_6 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000004578 168.0
WLSH2_k127_6394956_7 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000007843 167.0
WLSH2_k127_6394956_8 Cytidylate kinase-like family - - - 0.0000000000000000000000000000001906 134.0
WLSH2_k127_6394956_9 Flavin containing amine oxidoreductase - - - 0.000000000000000001429 98.0
WLSH2_k127_6435046_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000001884 160.0
WLSH2_k127_6435046_1 nuclease activity K18828 - - 0.00000000000000000000000000000000000001149 148.0
WLSH2_k127_6435046_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000002265 147.0
WLSH2_k127_6435046_3 - - - - 0.00000000000000002244 85.0
WLSH2_k127_6435046_4 - K21495 - - 0.000000000000005631 78.0
WLSH2_k127_6435046_6 negative regulation of transforming growth factor beta1 production K03068,K06261,K06593,K08867,K09187,K12488,K13738,K14972,K20050,K20371 GO:0000003,GO:0001654,GO:0001667,GO:0001745,GO:0002064,GO:0002065,GO:0002066,GO:0003006,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005938,GO:0006928,GO:0006996,GO:0007010,GO:0007015,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007298,GO:0007423,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0010564,GO:0010631,GO:0016020,GO:0016043,GO:0016477,GO:0017124,GO:0019904,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0030029,GO:0030036,GO:0030100,GO:0030154,GO:0030496,GO:0030707,GO:0030855,GO:0032153,GO:0032154,GO:0032155,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032794,GO:0032879,GO:0034329,GO:0034330,GO:0034332,GO:0034333,GO:0040011,GO:0043062,GO:0043063,GO:0044085,GO:0044421,GO:0044424,GO:0044425,GO:0044444,GO:0044448,GO:0044459,GO:0044464,GO:0044703,GO:0045171,GO:0045177,GO:0045179,GO:0045216,GO:0045807,GO:0048259,GO:0048260,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048592,GO:0048609,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0048870,GO:0050789,GO:0050794,GO:0050839,GO:0051049,GO:0051050,GO:0051128,GO:0051130,GO:0051179,GO:0051302,GO:0051674,GO:0051704,GO:0051726,GO:0060429,GO:0060627,GO:0065007,GO:0071840,GO:0071944,GO:0090130,GO:0090132,GO:0090596,GO:0097435,GO:0098590,GO:0099568,GO:0099738 2.1.1.43,2.7.11.1 0.000000007946 68.0
WLSH2_k127_6564165_0 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004699 269.0
WLSH2_k127_6564165_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000005192 238.0
WLSH2_k127_6564165_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000009295 117.0
WLSH2_k127_6564165_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000981 89.0
WLSH2_k127_6564165_4 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000003357 66.0
WLSH2_k127_6564165_5 phosphohydrolase (DHH superfamily) - - - 0.00000002968 66.0
WLSH2_k127_6564165_6 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.0008329 48.0
WLSH2_k127_6576790_0 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 402.0
WLSH2_k127_6576790_1 GMC oxidoreductase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 371.0
WLSH2_k127_6576790_10 - - - - 0.00000000000000000005984 95.0
WLSH2_k127_6576790_11 RNA recognition motif - - - 0.00000000000000001285 88.0
WLSH2_k127_6576790_12 Helix-turn-helix domain protein - - - 0.0000000002711 66.0
WLSH2_k127_6576790_13 Domain of unknown function (DUF4345) - - - 0.0005641 50.0
WLSH2_k127_6576790_2 short-chain dehydrogenase K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008411 248.0
WLSH2_k127_6576790_3 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009902 255.0
WLSH2_k127_6576790_4 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000005557 244.0
WLSH2_k127_6576790_5 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000003138 208.0
WLSH2_k127_6576790_6 Transcriptional regulator - - - 0.000000000000000000000000000000437 127.0
WLSH2_k127_6576790_7 RNA recognition motif - - - 0.00000000000000000000000002594 110.0
WLSH2_k127_6576790_8 domain, Protein K12287 - - 0.0000000000000000000000001998 119.0
WLSH2_k127_6576790_9 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000002162 101.0
WLSH2_k127_6663434_0 carnitine dehydratase K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 507.0
WLSH2_k127_6663434_1 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 417.0
WLSH2_k127_6663434_10 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000002273 194.0
WLSH2_k127_6663434_11 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000002914 205.0
WLSH2_k127_6663434_12 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000003849 164.0
WLSH2_k127_6663434_14 - - - - 0.000000000000000000000000000000000005066 143.0
WLSH2_k127_6663434_15 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000001177 72.0
WLSH2_k127_6663434_16 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000004942 60.0
WLSH2_k127_6663434_2 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 413.0
WLSH2_k127_6663434_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 320.0
WLSH2_k127_6663434_4 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
WLSH2_k127_6663434_5 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004341 259.0
WLSH2_k127_6663434_6 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001126 229.0
WLSH2_k127_6663434_7 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000003449 216.0
WLSH2_k127_6663434_8 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000006711 231.0
WLSH2_k127_6663434_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000001219 210.0
WLSH2_k127_66705_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 5.07e-203 645.0
WLSH2_k127_66705_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 571.0
WLSH2_k127_66705_10 Belongs to the peptidase S16 family - - - 0.00000000001523 70.0
WLSH2_k127_66705_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000522 251.0
WLSH2_k127_66705_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657,K07662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004953 250.0
WLSH2_k127_66705_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001228 250.0
WLSH2_k127_66705_5 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000122 183.0
WLSH2_k127_66705_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000001468 138.0
WLSH2_k127_66705_7 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000001647 116.0
WLSH2_k127_66705_8 PFAM polysaccharide export protein K01991 - - 0.0000000000000000000005981 105.0
WLSH2_k127_66705_9 alginic acid biosynthetic process - - - 0.000000000001653 80.0
WLSH2_k127_6672030_0 Integrase core domain - - - 0.00000000000000000000000000000000007546 135.0
WLSH2_k127_6672030_1 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000636 141.0
WLSH2_k127_6672030_2 Transposase zinc-binding domain - - - 0.00000000000000000000000000002101 126.0
WLSH2_k127_6720819_0 Bacterial protein of unknown function (DUF853) K06915 - - 6.827e-260 807.0
WLSH2_k127_6720819_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 1.34e-259 829.0
WLSH2_k127_6720819_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000003367 119.0
WLSH2_k127_6720819_11 Protein of unknown function (DUF2868) - - - 0.00000000000000000000000002804 125.0
WLSH2_k127_6720819_12 PFAM Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000007254 110.0
WLSH2_k127_6720819_13 manually curated - - - 0.0000000000000000000000005302 106.0
WLSH2_k127_6720819_14 - - - - 0.00000000000000000000007746 100.0
WLSH2_k127_6720819_15 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000008669 96.0
WLSH2_k127_6720819_16 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000156 87.0
WLSH2_k127_6720819_17 - - - - 0.00000000000000002917 83.0
WLSH2_k127_6720819_18 Protein of unknown function (DUF1566) - - - 0.000000001658 67.0
WLSH2_k127_6720819_19 Serine aminopeptidase, S33 - - - 0.00000109 53.0
WLSH2_k127_6720819_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 3.753e-213 696.0
WLSH2_k127_6720819_20 Bacterial pre-peptidase C-terminal domain - - - 0.00001205 55.0
WLSH2_k127_6720819_22 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0001216 51.0
WLSH2_k127_6720819_23 Plasmid stability protein K21495 - - 0.0001659 47.0
WLSH2_k127_6720819_3 4Fe-4S dicluster domain K17048,K17051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 406.0
WLSH2_k127_6720819_4 Permease family K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 392.0
WLSH2_k127_6720819_5 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 303.0
WLSH2_k127_6720819_6 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000002019 249.0
WLSH2_k127_6720819_7 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000007781 179.0
WLSH2_k127_6720819_8 COG1715 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000005306 156.0
WLSH2_k127_6720819_9 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000001226 131.0
WLSH2_k127_674658_0 Glycosyltransferase like family 2 K00786,K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 410.0
WLSH2_k127_674658_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 295.0
WLSH2_k127_676946_0 DEAD DEAH box helicase K03654 - 3.6.4.12 2.605e-208 671.0
WLSH2_k127_676946_1 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 406.0
WLSH2_k127_676946_10 Acetyl propionyl-CoA carboxylase alpha subunit K02160 - - 0.0000000000002325 72.0
WLSH2_k127_676946_12 Belongs to the binding-protein-dependent transport system permease family K02057,K10440 - - 0.00000005062 56.0
WLSH2_k127_676946_13 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000842 46.0
WLSH2_k127_676946_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006816 286.0
WLSH2_k127_676946_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000007913 209.0
WLSH2_k127_676946_4 DoxX - - - 0.000000000000000000000000000000000000000000000000000006622 194.0
WLSH2_k127_676946_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000008342 192.0
WLSH2_k127_676946_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000003765 168.0
WLSH2_k127_676946_7 Redoxin domain protein - - - 0.000000000000000000000000000000000000000003005 163.0
WLSH2_k127_676946_8 Putative transposase - - - 0.00000000000000000000000002416 119.0
WLSH2_k127_678463_0 TIGRFAM cysteine-rich repeat protein - - - 0.0000000000000000000000003486 123.0
WLSH2_k127_678463_1 Domain of unknown function (DUF4215) - - - 0.0000000611 65.0
WLSH2_k127_6841406_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 488.0
WLSH2_k127_6841406_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 498.0
WLSH2_k127_6841406_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 410.0
WLSH2_k127_6841406_3 HDOD domain - - - 0.0000000000000000000000000000000000000006829 166.0
WLSH2_k127_6841406_4 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000002293 154.0
WLSH2_k127_6891497_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.338e-303 949.0
WLSH2_k127_6891497_1 Aminotransferase class-V K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 617.0
WLSH2_k127_6891497_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 297.0
WLSH2_k127_6891497_11 Uncharacterised protein family (UPF0014) K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 295.0
WLSH2_k127_6891497_12 IMP dehydrogenase / GMP reductase domain K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000009336 229.0
WLSH2_k127_6891497_13 Belongs to the pseudouridine synthase RluA family - - - 0.00000000000000000000000000000000000000000000000000000000000002823 228.0
WLSH2_k127_6891497_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000001553 207.0
WLSH2_k127_6891497_15 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000000000000000000000000000000000000000000008688 176.0
WLSH2_k127_6891497_16 Pfam ABC K02068 - - 0.00000000000000000000000000000000000000000004412 168.0
WLSH2_k127_6891497_17 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000029 138.0
WLSH2_k127_6891497_18 DnaJ molecular chaperone homology domain K03686 - - 0.00000000000000000000000000000001024 136.0
WLSH2_k127_6891497_19 - - - - 0.0000000000000000000000007702 108.0
WLSH2_k127_6891497_2 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 567.0
WLSH2_k127_6891497_20 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000001574 103.0
WLSH2_k127_6891497_21 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000216 83.0
WLSH2_k127_6891497_22 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000007463 81.0
WLSH2_k127_6891497_3 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 496.0
WLSH2_k127_6891497_4 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 503.0
WLSH2_k127_6891497_5 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 490.0
WLSH2_k127_6891497_6 ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 407.0
WLSH2_k127_6891497_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 334.0
WLSH2_k127_6891497_8 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 336.0
WLSH2_k127_6891497_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 309.0
WLSH2_k127_6911338_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 533.0
WLSH2_k127_6911338_1 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000001219 234.0
WLSH2_k127_6911338_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000003089 219.0
WLSH2_k127_6911338_3 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000001623 188.0
WLSH2_k127_6911338_4 - - - - 0.0000000000004556 78.0
WLSH2_k127_6911338_5 - - - - 0.00000000003312 70.0
WLSH2_k127_6969095_0 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000006396 221.0
WLSH2_k127_6969095_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000005355 168.0
WLSH2_k127_6969095_2 GAF domain - - - 0.00000000000000000000000000000001854 141.0
WLSH2_k127_6969095_3 Serine aminopeptidase, S33 - - - 0.000000001489 63.0
WLSH2_k127_6969095_4 - - - - 0.0001077 50.0
WLSH2_k127_6970818_0 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 404.0
WLSH2_k127_6984717_0 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 1.098e-317 981.0
WLSH2_k127_6984717_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX - - - 2.398e-194 614.0
WLSH2_k127_6984717_2 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 568.0
WLSH2_k127_6984717_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 346.0
WLSH2_k127_6984717_4 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000002153 193.0
WLSH2_k127_6984717_5 (Lipo)protein K04754 - - 0.00000000000000000000000000002171 126.0
WLSH2_k127_6984717_6 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000022 114.0
WLSH2_k127_7003939_0 hydrolase, family 3 K05349 - 3.2.1.21 5.541e-264 835.0
WLSH2_k127_7003939_1 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000001551 183.0
WLSH2_k127_7003939_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000001716 132.0
WLSH2_k127_7048790_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 599.0
WLSH2_k127_7048790_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002105 241.0
WLSH2_k127_7048790_2 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000001293 147.0
WLSH2_k127_7048790_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000001184 78.0
WLSH2_k127_708183_0 Belongs to the CarB family K01955 - 6.3.5.5 1.64e-318 989.0
WLSH2_k127_708183_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 4.543e-229 726.0
WLSH2_k127_708183_10 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000005784 227.0
WLSH2_k127_708183_11 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000005755 201.0
WLSH2_k127_708183_12 Lysin motif - - - 0.000000000000000000000000000000000000000000002102 174.0
WLSH2_k127_708183_13 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000002293 176.0
WLSH2_k127_708183_14 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000001308 136.0
WLSH2_k127_708183_15 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000001491 130.0
WLSH2_k127_708183_16 Tetratricopeptide repeat - - - 0.000000000000000000001252 109.0
WLSH2_k127_708183_17 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000001336 99.0
WLSH2_k127_708183_18 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000002961 77.0
WLSH2_k127_708183_19 KR domain - - - 0.0000000000001388 71.0
WLSH2_k127_708183_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 581.0
WLSH2_k127_708183_20 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000003353 67.0
WLSH2_k127_708183_3 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 511.0
WLSH2_k127_708183_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 484.0
WLSH2_k127_708183_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 381.0
WLSH2_k127_708183_6 PFAM Enoyl-CoA hydratase isomerase K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 288.0
WLSH2_k127_708183_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 286.0
WLSH2_k127_708183_8 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007935 284.0
WLSH2_k127_708183_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000006576 260.0
WLSH2_k127_7179521_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1685.0
WLSH2_k127_7179521_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 440.0
WLSH2_k127_7179521_2 phosphorelay signal transduction system K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 423.0
WLSH2_k127_7179521_3 GHKL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000093 275.0
WLSH2_k127_7179521_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000008914 248.0
WLSH2_k127_7179521_5 IMP dehydrogenase activity K04767,K07182 - - 0.0000000000000000001208 96.0
WLSH2_k127_7212746_0 Uncharacterized protein family (UPF0051) K09014 - - 5.285e-257 797.0
WLSH2_k127_7212746_1 Cysteine desulfurase K01766,K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 576.0
WLSH2_k127_7212746_2 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 413.0
WLSH2_k127_7212746_3 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 356.0
WLSH2_k127_7212746_4 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000001215 204.0
WLSH2_k127_7212746_5 Transcriptional regulator - - - 0.0000000000000000000000000000228 123.0
WLSH2_k127_7212746_6 Belongs to the UPF0173 family - - - 0.0000008365 59.0
WLSH2_k127_7362861_0 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 550.0
WLSH2_k127_7362861_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 505.0
WLSH2_k127_7362861_2 coenzyme binding K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 426.0
WLSH2_k127_7362861_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 370.0
WLSH2_k127_7362861_4 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 366.0
WLSH2_k127_7362861_5 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01426,K12251,K13566 - 3.5.1.3,3.5.1.4,3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000007017 240.0
WLSH2_k127_7362861_6 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000002521 91.0
WLSH2_k127_7475748_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 601.0
WLSH2_k127_7475748_1 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 598.0
WLSH2_k127_7475748_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 380.0
WLSH2_k127_7475748_3 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 329.0
WLSH2_k127_7475748_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001471 263.0
WLSH2_k127_7475748_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000143 214.0
WLSH2_k127_7475748_6 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000000000000000000000000001821 203.0
WLSH2_k127_7475748_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000008873 194.0
WLSH2_k127_7475748_8 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000001339 171.0
WLSH2_k127_7475748_9 Nitronate monooxygenase K00459 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813 1.13.12.16 0.00000000001409 64.0
WLSH2_k127_7517461_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.207e-260 820.0
WLSH2_k127_7517461_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 422.0
WLSH2_k127_7517461_10 PFAM YbbR family protein - - - 0.000004835 58.0
WLSH2_k127_7517461_2 LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 294.0
WLSH2_k127_7517461_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004582 282.0
WLSH2_k127_7517461_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001711 277.0
WLSH2_k127_7517461_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000003057 254.0
WLSH2_k127_7517461_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000003535 250.0
WLSH2_k127_7517461_7 PFAM metallophosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000002564 167.0
WLSH2_k127_7517461_8 Biotin/lipoate A/B protein ligase family K03801 - 2.3.1.181 0.000000000000000000000000000000000000000004348 165.0
WLSH2_k127_7517461_9 PhoQ Sensor - - - 0.00000000000005421 77.0
WLSH2_k127_7537017_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 460.0
WLSH2_k127_7537017_1 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001777 214.0
WLSH2_k127_7537017_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000589 195.0
WLSH2_k127_7537017_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000001009 192.0
WLSH2_k127_7537017_4 PFAM CMP dCMP deaminase zinc-binding K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000003722 180.0
WLSH2_k127_7714116_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1047.0
WLSH2_k127_7714116_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.188e-287 902.0
WLSH2_k127_7714116_10 Histidine kinase - - - 0.00000000000001725 78.0
WLSH2_k127_7714116_11 - - - - 0.00000000000002278 76.0
WLSH2_k127_7714116_12 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0005006 48.0
WLSH2_k127_7714116_2 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 455.0
WLSH2_k127_7714116_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 437.0
WLSH2_k127_7714116_4 AIR synthase related protein, N-terminal domain K01933,K11788 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 324.0
WLSH2_k127_7714116_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000002834 278.0
WLSH2_k127_7714116_6 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000003112 249.0
WLSH2_k127_7714116_7 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000001709 186.0
WLSH2_k127_7714116_8 Belongs to the ParB family K03497 GO:0005575,GO:0005622,GO:0005623,GO:0007059,GO:0008150,GO:0009295,GO:0009987,GO:0022603,GO:0042173,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0043937,GO:0043938,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0065007 - 0.0000000000000000000000000000000000000003966 160.0
WLSH2_k127_7714116_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000562 82.0
WLSH2_k127_7724299_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 347.0
WLSH2_k127_7724299_1 Iron-sulfur cluster-binding domain K06871 - - 0.000000000000000000000000000000000000000000000000000005156 207.0
WLSH2_k127_7724299_2 PFAM 4Fe-4S binding domain K00124 - - 0.00000000000006507 74.0
WLSH2_k127_7724299_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000001239 57.0
WLSH2_k127_7825739_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 492.0
WLSH2_k127_7825739_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 444.0
WLSH2_k127_7825739_2 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001129 244.0
WLSH2_k127_7825739_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000004996 183.0
WLSH2_k127_7825739_4 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.00000000000000000000000000000000000007525 158.0
WLSH2_k127_7825739_5 calcium- and calmodulin-responsive adenylate cyclase activity K11005 - - 0.0000000000000000000000000003015 132.0
WLSH2_k127_7825739_6 PFAM MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000009401 121.0
WLSH2_k127_7825739_7 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000004112 123.0
WLSH2_k127_7825739_8 3-phytase K01083 - 3.1.3.8 0.00001315 58.0
WLSH2_k127_7868367_0 Acyl-CoA dehydrogenase N terminal K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 404.0
WLSH2_k127_7868367_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 315.0
WLSH2_k127_7868367_2 PIN domain K07065 - - 0.000000000000000000000000000000000000003053 151.0
WLSH2_k127_7868367_3 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000002363 134.0
WLSH2_k127_7883091_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 475.0
WLSH2_k127_7883091_1 PFAM Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 423.0
WLSH2_k127_7883091_10 Domain of unknown function (DUF4215) - - - 0.000005886 61.0
WLSH2_k127_7883091_2 SNF2 family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 361.0
WLSH2_k127_7883091_5 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.000000000000000000007131 110.0
WLSH2_k127_7883091_7 Calcineurin-like phosphoesterase - - - 0.00000000000000000174 102.0
WLSH2_k127_7883091_8 Calcineurin-like phosphoesterase - - - 0.000000000000000003014 102.0
WLSH2_k127_7883091_9 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000007404 82.0
WLSH2_k127_7915516_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 545.0
WLSH2_k127_7915516_1 Phosphate transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 306.0
WLSH2_k127_7915516_2 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000003869 122.0
WLSH2_k127_7915516_3 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000635 108.0
WLSH2_k127_7915516_4 Histidine kinase K07636 - 2.7.13.3 0.0000000006458 60.0
WLSH2_k127_7936488_0 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 481.0
WLSH2_k127_7936488_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007765 244.0
WLSH2_k127_7936488_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000008551 242.0
WLSH2_k127_7936488_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000005973 93.0
WLSH2_k127_7936488_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000003973 77.0
WLSH2_k127_7937067_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 477.0
WLSH2_k127_7937067_1 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 458.0
WLSH2_k127_7937067_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 425.0
WLSH2_k127_7937067_3 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 384.0
WLSH2_k127_7937067_4 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 361.0
WLSH2_k127_7937067_5 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 332.0
WLSH2_k127_7937067_6 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.00000000000000000000000000000000000000001381 165.0
WLSH2_k127_7937067_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000006506 158.0
WLSH2_k127_7937067_8 Acyl-coenzyme A thioesterase K17362 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016043,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0047617,GO:0051186,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.00000000000004728 78.0
WLSH2_k127_7937067_9 response to stress - - - 0.0000000000001991 78.0
WLSH2_k127_7957091_0 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 434.0
WLSH2_k127_7957091_1 Belongs to the transketolase family K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 316.0
WLSH2_k127_7957091_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
WLSH2_k127_7957091_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000003594 201.0
WLSH2_k127_7957091_4 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000001313 179.0
WLSH2_k127_796137_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 388.0
WLSH2_k127_796137_1 Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07264 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016763,GO:0033692,GO:0034637,GO:0034645,GO:0042221,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0050896,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.2.43 0.000000000000000000000000008568 124.0
WLSH2_k127_7973791_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 302.0
WLSH2_k127_7973791_1 Pilus assembly protein PilX K02673 - - 0.0000001565 64.0
WLSH2_k127_7973791_2 pilus assembly protein PilW - - - 0.0000002374 61.0
WLSH2_k127_7973791_3 protein transport across the cell outer membrane K02246,K08084 - - 0.000003977 57.0
WLSH2_k127_7986505_0 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 371.0
WLSH2_k127_7986505_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000002148 234.0
WLSH2_k127_7986505_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000008491 224.0
WLSH2_k127_7986505_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000004213 206.0
WLSH2_k127_7986505_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000000008037 64.0
WLSH2_k127_8051706_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 512.0
WLSH2_k127_8051706_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 406.0
WLSH2_k127_8051706_2 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 309.0
WLSH2_k127_8051706_3 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 260.0
WLSH2_k127_8051706_4 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
WLSH2_k127_8051706_5 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000002607 138.0
WLSH2_k127_8051706_6 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000006841 110.0
WLSH2_k127_8060366_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 552.0
WLSH2_k127_8060366_1 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 372.0
WLSH2_k127_8060366_2 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 350.0
WLSH2_k127_8060366_3 Glycosyl transferase family 21 K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 299.0
WLSH2_k127_8060366_4 PFAM YdjC family protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000296 261.0
WLSH2_k127_8060366_5 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000007704 218.0
WLSH2_k127_8060366_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.0000007656 60.0
WLSH2_k127_8060366_7 Hsp20/alpha crystallin family K13993 - - 0.00001217 53.0
WLSH2_k127_8060366_9 HesB YadR YfhF-family protein - - - 0.00009995 51.0
WLSH2_k127_812834_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 610.0
WLSH2_k127_812834_1 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 566.0
WLSH2_k127_812834_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000007235 220.0
WLSH2_k127_812834_11 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000001724 222.0
WLSH2_k127_812834_12 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002037 190.0
WLSH2_k127_812834_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000008483 193.0
WLSH2_k127_812834_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000001428 175.0
WLSH2_k127_812834_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001598 168.0
WLSH2_k127_812834_16 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001001 164.0
WLSH2_k127_812834_17 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001247 160.0
WLSH2_k127_812834_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000001035 152.0
WLSH2_k127_812834_19 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000004865 137.0
WLSH2_k127_812834_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 546.0
WLSH2_k127_812834_20 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000005274 132.0
WLSH2_k127_812834_21 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000009274 95.0
WLSH2_k127_812834_22 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000005527 68.0
WLSH2_k127_812834_23 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000002586 66.0
WLSH2_k127_812834_24 peptidoglycan binding - - - 0.000004978 58.0
WLSH2_k127_812834_3 TIGRFAM arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 534.0
WLSH2_k127_812834_4 RNA polymerases D K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 411.0
WLSH2_k127_812834_5 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 324.0
WLSH2_k127_812834_6 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 307.0
WLSH2_k127_812834_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 289.0
WLSH2_k127_812834_8 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 282.0
WLSH2_k127_812834_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002208 274.0
WLSH2_k127_8272775_0 Cytochrome c554 and c-prime - - - 4.644e-284 897.0
WLSH2_k127_8272775_1 glutamate catabolic process to 2-oxoglutarate K15371 - 1.4.1.2 1.48e-224 753.0
WLSH2_k127_8272775_10 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000004292 216.0
WLSH2_k127_8272775_11 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000584 224.0
WLSH2_k127_8272775_12 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000009171 217.0
WLSH2_k127_8272775_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000004116 186.0
WLSH2_k127_8272775_14 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000003471 177.0
WLSH2_k127_8272775_15 Terminase - - - 0.0000000000000000000000000000000000000000001211 163.0
WLSH2_k127_8272775_16 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000247 165.0
WLSH2_k127_8272775_17 Transposase zinc-binding domain - - - 0.00000000000000000000000000000009975 131.0
WLSH2_k127_8272775_18 PFAM SpoVT AbrB K07172 - - 0.000000000000000000000000000006971 122.0
WLSH2_k127_8272775_19 Putative transposase - - - 0.000000000000000003701 92.0
WLSH2_k127_8272775_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K01719,K13542 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.1.1.37,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 468.0
WLSH2_k127_8272775_20 Kazal type serine protease inhibitors - - - 0.000000000000000004198 96.0
WLSH2_k127_8272775_21 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000006025 96.0
WLSH2_k127_8272775_22 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0000000000000000533 83.0
WLSH2_k127_8272775_24 - - - - 0.000000000000005819 81.0
WLSH2_k127_8272775_25 4Fe-4S binding domain protein K00176 - 1.2.7.3 0.000000002676 62.0
WLSH2_k127_8272775_26 Terminase - - - 0.00000001026 57.0
WLSH2_k127_8272775_27 arylsulfatase a - - - 0.000001576 61.0
WLSH2_k127_8272775_28 metalloendopeptidase activity K06261,K08867,K09187,K14972,K20371 - 2.1.1.43,2.7.11.1 0.0002413 52.0
WLSH2_k127_8272775_29 - - - - 0.0004875 51.0
WLSH2_k127_8272775_3 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009971 475.0
WLSH2_k127_8272775_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 382.0
WLSH2_k127_8272775_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 320.0
WLSH2_k127_8272775_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 303.0
WLSH2_k127_8272775_7 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 303.0
WLSH2_k127_8272775_8 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000268 253.0
WLSH2_k127_8272775_9 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
WLSH2_k127_8288689_0 Protein of unknown function (DUF1016) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 399.0
WLSH2_k127_8288689_1 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 281.0
WLSH2_k127_8288689_10 Domain of unknown function (DUF4411) - - - 0.00000000000000000002764 97.0
WLSH2_k127_8288689_11 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000001343 87.0
WLSH2_k127_8288689_12 Protein of unknown function (DUF1566) - - - 0.000000000008215 75.0
WLSH2_k127_8288689_13 Protein conserved in bacteria - - - 0.0006968 44.0
WLSH2_k127_8288689_2 aldo keto reductase K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000787 273.0
WLSH2_k127_8288689_3 HsdM N-terminal domain K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000005893 258.0
WLSH2_k127_8288689_4 COG0671 Membrane-associated phospholipid phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000005188 219.0
WLSH2_k127_8288689_5 IrrE N-terminal-like domain - - - 0.000000000000000000000000000000000000000000000000001212 193.0
WLSH2_k127_8288689_6 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000004552 188.0
WLSH2_k127_8288689_7 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000101 156.0
WLSH2_k127_8288689_8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 - - 0.0000000000000000000000000000000000001253 144.0
WLSH2_k127_8288689_9 ORF6N domain - - - 0.0000000000000000000004269 101.0
WLSH2_k127_832101_0 Acyl-CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 505.0
WLSH2_k127_832101_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 501.0
WLSH2_k127_832101_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 481.0
WLSH2_k127_832101_3 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 372.0
WLSH2_k127_832101_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000002837 226.0
WLSH2_k127_832101_5 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000000000000000000000000000000000001648 214.0
WLSH2_k127_832101_6 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.0000000000000000000000000000003883 132.0
WLSH2_k127_832101_7 - - - - 0.000000000000000007649 89.0
WLSH2_k127_8362791_0 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 311.0
WLSH2_k127_8362791_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000001523 233.0
WLSH2_k127_8362791_10 Glycine-zipper domain - - - 0.00000000000000000000000000003179 121.0
WLSH2_k127_8362791_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
WLSH2_k127_8362791_3 KR domain K00034,K00059 - 1.1.1.100,1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000006791 222.0
WLSH2_k127_8362791_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000006461 194.0
WLSH2_k127_8362791_5 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000004674 144.0
WLSH2_k127_8362791_6 Transcriptional - - - 0.000000000000000000000000000000000006379 139.0
WLSH2_k127_8362791_7 Amidohydrolase - - - 0.0000000000000000000000000000000003446 136.0
WLSH2_k127_8362791_8 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000002736 141.0
WLSH2_k127_8362791_9 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.00000000000000000000000000001883 122.0
WLSH2_k127_8428383_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 458.0
WLSH2_k127_8428383_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 364.0
WLSH2_k127_8428383_2 Type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 334.0
WLSH2_k127_8428383_3 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000006859 134.0
WLSH2_k127_8428383_4 Pilus assembly protein, PilP K02665 - - 0.000000000000001804 85.0
WLSH2_k127_8428383_5 Type IV pilus assembly protein PilM; K02662 - - 0.00000004705 55.0
WLSH2_k127_8428383_6 PFAM Fimbrial assembly family protein K02663 - - 0.0000002515 59.0
WLSH2_k127_8486520_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 372.0
WLSH2_k127_8486520_1 S1, RNA binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 338.0
WLSH2_k127_8486520_10 Protein of unknown function (DUF559) - - - 0.0002263 45.0
WLSH2_k127_8486520_2 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 292.0
WLSH2_k127_8486520_3 TatD DNase domain containing 3 K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000007932 235.0
WLSH2_k127_8486520_4 Lactamase, beta 2 - GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0031974,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000103 235.0
WLSH2_k127_8486520_5 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000001117 224.0
WLSH2_k127_8486520_6 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000009683 100.0
WLSH2_k127_8486520_7 - - - - 0.00000000000000000002057 100.0
WLSH2_k127_8486520_8 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000002139 87.0
WLSH2_k127_8486520_9 HicA toxin of bacterial toxin-antitoxin, - - - 0.00007285 51.0
WLSH2_k127_8492726_0 Peptidase M1 membrane alanine aminopeptidase K01256,K08776 - 3.4.11.2 6.502e-201 659.0
WLSH2_k127_8492726_1 Belongs to the peptidase S11 family K01286,K07258 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008397 280.0
WLSH2_k127_8492726_10 amine dehydrogenase activity - - - 0.000000000000000000000000000000009757 143.0
WLSH2_k127_8492726_11 signal transduction histidine kinase - - - 0.000000000000000000000000003397 120.0
WLSH2_k127_8492726_12 - - - - 0.000000008318 59.0
WLSH2_k127_8492726_13 DNA-sulfur modification-associated - - - 0.00000004495 65.0
WLSH2_k127_8492726_14 Enoyl-CoA hydratase/isomerase - - - 0.0000006536 54.0
WLSH2_k127_8492726_15 Lytic polysaccharide mono-oxygenase, cellulose-degrading - - - 0.00000349 61.0
WLSH2_k127_8492726_16 PFAM conserved - - - 0.00004129 48.0
WLSH2_k127_8492726_17 Lactonase, 7-bladed beta-propeller K07404 - 3.1.1.31 0.0008011 53.0
WLSH2_k127_8492726_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002731 266.0
WLSH2_k127_8492726_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000007131 227.0
WLSH2_k127_8492726_4 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000006525 218.0
WLSH2_k127_8492726_5 Transglycosylase SLT domain K06381,K08309 - - 0.00000000000000000000000000000000000000000000000000001493 214.0
WLSH2_k127_8492726_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000001131 167.0
WLSH2_k127_8492726_7 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000165 166.0
WLSH2_k127_8492726_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000001216 156.0
WLSH2_k127_8492726_9 THUMP - - - 0.000000000000000000000000000000009235 135.0
WLSH2_k127_8505294_0 coenzyme binding K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 443.0
WLSH2_k127_8505294_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 294.0
WLSH2_k127_8505294_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000007885 223.0
WLSH2_k127_8505294_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
WLSH2_k127_8505294_4 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000629 184.0
WLSH2_k127_8505294_5 - - - - 0.00000000000000001483 85.0
WLSH2_k127_8505294_6 PFAM Methyltransferase type 11 - - - 0.00000000001576 66.0
WLSH2_k127_8536272_0 InterPro IPR007367 - - - 0.0000000000000000000000000000000000000000002578 162.0
WLSH2_k127_8536272_1 - - - - 0.000000000000000000000000000000000000009271 149.0
WLSH2_k127_8536272_10 COG0477 Permeases of the major facilitator superfamily - - - 0.00001643 49.0
WLSH2_k127_8536272_2 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000002201 130.0
WLSH2_k127_8536272_3 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000009353 111.0
WLSH2_k127_8536272_4 Protein of unknown function DUF86 - - - 0.000000000000000000002078 95.0
WLSH2_k127_8536272_5 Major facilitator Superfamily - - - 0.0000000000000001814 85.0
WLSH2_k127_8536272_6 PIN domain - - - 0.0000000000001707 76.0
WLSH2_k127_8536272_7 Lipid A core-O-antigen ligase-like enyme K18814 - - 0.0000000001263 66.0
WLSH2_k127_8536272_8 PFAM Glycosyl transferases group 1 - - - 0.0000002339 57.0
WLSH2_k127_8536272_9 Ribbon-helix-helix protein, copG family - - - 0.000005069 52.0
WLSH2_k127_8556530_0 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 531.0
WLSH2_k127_8556530_1 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 391.0
WLSH2_k127_8556530_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 380.0
WLSH2_k127_8556530_3 Cytochrome b subunit of formate dehydrogenase-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 312.0
WLSH2_k127_8556530_4 - - - - 0.00000000000000000000000000000000000000000000000000008547 191.0
WLSH2_k127_8556530_5 - - - - 0.0000000000000005161 83.0
WLSH2_k127_8559011_0 Methionine synthase K00548 - 2.1.1.13 0.0 1628.0
WLSH2_k127_8559011_1 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 7.292e-197 633.0
WLSH2_k127_8559011_2 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 449.0
WLSH2_k127_8559011_3 chorismate binding enzyme K01851,K02552 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 5.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 347.0
WLSH2_k127_8559011_4 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 302.0
WLSH2_k127_8559011_5 YsiA-like protein, C-terminal region K13770 - - 0.00000000000000000000000000000000000000000000000000000000000006589 220.0
WLSH2_k127_8559011_6 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000000000000000000000003652 233.0
WLSH2_k127_8559011_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000006481 186.0
WLSH2_k127_8559011_8 SPTR CopG domain protein DNA-binding domain protein - - - 0.000000000000003576 77.0
WLSH2_k127_8559011_9 Integrase - - - 0.00000001689 62.0
WLSH2_k127_8624345_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 451.0
WLSH2_k127_8624345_1 Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
WLSH2_k127_8624345_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000007189 195.0
WLSH2_k127_8624345_3 ubiE/COQ5 methyltransferase family K03183,K05929 - 2.1.1.103,2.1.1.163,2.1.1.201 0.00000000000000000000000000001764 129.0
WLSH2_k127_8692007_0 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 369.0
WLSH2_k127_8692007_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000001811 169.0
WLSH2_k127_8692007_10 - - - - 0.0000003774 59.0
WLSH2_k127_8692007_2 Acyltransferase family - - - 0.00000000000000000000000000000000000001493 158.0
WLSH2_k127_8692007_3 - - - - 0.00000000000000000000001477 101.0
WLSH2_k127_8692007_4 Protein of unknown function (DUF2283) - - - 0.00000000000000000000172 94.0
WLSH2_k127_8692007_5 - - - - 0.000000000000000000004151 94.0
WLSH2_k127_8692007_7 Protein of unknown function (DUF433) - - - 0.0000000000009099 74.0
WLSH2_k127_8692007_8 - - - - 0.00000000005386 65.0
WLSH2_k127_8692007_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000008158 60.0
WLSH2_k127_8721234_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18687 - 6.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 596.0
WLSH2_k127_8721234_1 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000009913 235.0
WLSH2_k127_8721234_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000006852 221.0
WLSH2_k127_8721234_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000008496 179.0
WLSH2_k127_8721234_4 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000001598 162.0
WLSH2_k127_8721234_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0008098 53.0
WLSH2_k127_8726313_0 Elongation factor Tu domain 2 K02355 - - 1.555e-232 739.0
WLSH2_k127_8726313_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 324.0
WLSH2_k127_8726313_2 - - - - 0.00000000000000000000000000000000001593 143.0
WLSH2_k127_8726313_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000001135 56.0
WLSH2_k127_8742558_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 291.0
WLSH2_k127_8742558_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
WLSH2_k127_8742558_10 nucleic acid binding K01174 - 3.1.31.1 0.000000000242 71.0
WLSH2_k127_8742558_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000003175 61.0
WLSH2_k127_8742558_12 NHL repeat containing protein K01406 - 3.4.24.40 0.000003207 59.0
WLSH2_k127_8742558_13 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.00002735 50.0
WLSH2_k127_8742558_2 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001728 229.0
WLSH2_k127_8742558_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000001662 184.0
WLSH2_k127_8742558_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000003112 164.0
WLSH2_k127_8742558_5 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000009445 153.0
WLSH2_k127_8742558_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000003152 143.0
WLSH2_k127_8742558_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000008703 117.0
WLSH2_k127_8742558_8 - - - - 0.000000000000000009071 86.0
WLSH2_k127_8742558_9 addiction module antidote protein, CC2985 family K07746 - - 0.0000000000004801 72.0
WLSH2_k127_8746668_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 452.0
WLSH2_k127_8746668_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 344.0
WLSH2_k127_8746668_2 PFAM HDOD domain - - - 0.00000000000000000000000000005614 128.0
WLSH2_k127_8746668_3 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000001075 92.0
WLSH2_k127_8746668_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000001399 75.0
WLSH2_k127_876924_0 AMP-binding enzyme C-terminal domain K00666 - - 3.442e-302 936.0
WLSH2_k127_876924_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 501.0
WLSH2_k127_876924_10 MaoC like domain - - - 0.000000000000000000000000000000000000000000000004894 177.0
WLSH2_k127_876924_11 Plasmid stabilization system - - - 0.00000000000000000000000006914 108.0
WLSH2_k127_876924_13 Putative addiction module component - - - 0.000000000000000000948 88.0
WLSH2_k127_876924_14 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000004063 70.0
WLSH2_k127_876924_16 N-acetylmuramoyl-L-alanine amidase K01446 GO:0001519,GO:0001817,GO:0001818,GO:0002218,GO:0002221,GO:0002253,GO:0002376,GO:0002682,GO:0002683,GO:0002684,GO:0002694,GO:0002695,GO:0002697,GO:0002698,GO:0002757,GO:0002758,GO:0002764,GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0006518,GO:0006807,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008329,GO:0008745,GO:0009595,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0016019,GO:0016020,GO:0016045,GO:0016787,GO:0016810,GO:0016811,GO:0019730,GO:0023052,GO:0031179,GO:0031347,GO:0031349,GO:0032101,GO:0032649,GO:0032689,GO:0032814,GO:0032815,GO:0032823,GO:0032824,GO:0032826,GO:0032827,GO:0034641,GO:0038023,GO:0038187,GO:0040007,GO:0042742,GO:0042834,GO:0043207,GO:0043603,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044403,GO:0044419,GO:0044464,GO:0045087,GO:0045088,GO:0045089,GO:0045595,GO:0045596,GO:0045619,GO:0045620,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050727,GO:0050776,GO:0050777,GO:0050778,GO:0050789,GO:0050793,GO:0050794,GO:0050830,GO:0050865,GO:0050866,GO:0050896,GO:0051093,GO:0051239,GO:0051241,GO:0051249,GO:0051250,GO:0051606,GO:0051704,GO:0051707,GO:0051716,GO:0060089,GO:0061783,GO:0065007,GO:0071704,GO:0080134,GO:0097367,GO:0098542,GO:0098543,GO:0098581,GO:1901564,GO:1902105,GO:1902106,GO:1903706,GO:1903707,GO:2000026 - 0.00000000006869 70.0
WLSH2_k127_876924_17 Integrase core domain K07497 - - 0.00001278 57.0
WLSH2_k127_876924_18 Integrase - - - 0.00005941 48.0
WLSH2_k127_876924_19 Transposase - - - 0.00008225 54.0
WLSH2_k127_876924_2 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 391.0
WLSH2_k127_876924_3 Oxidoreductase FAD-binding domain K00523,K14581,K16246,K18225 - 1.17.1.1,1.18.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 376.0
WLSH2_k127_876924_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K09251 - 2.6.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 355.0
WLSH2_k127_876924_5 Oxidoreductase FAD-binding domain K00523,K14581,K16246,K18225 - 1.17.1.1,1.18.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 329.0
WLSH2_k127_876924_6 Transposase, Mutator family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 325.0
WLSH2_k127_876924_7 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 328.0
WLSH2_k127_876924_8 Transposase zinc-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 299.0
WLSH2_k127_876924_9 Bacterial regulatory proteins TetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002933 267.0
WLSH2_k127_8780186_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.824e-256 816.0
WLSH2_k127_8780186_1 Cytochrome C assembly protein K02198,K04016 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 587.0
WLSH2_k127_8780186_10 PKD domain - - - 0.000000000008122 72.0
WLSH2_k127_8780186_11 Caspase domain - - - 0.00000000006879 62.0
WLSH2_k127_8780186_12 PFAM PemK-like protein K07171 - - 0.000000009583 61.0
WLSH2_k127_8780186_13 Tetratricopeptide repeat - - - 0.00000004516 64.0
WLSH2_k127_8780186_14 PIN domain - - - 0.00000006208 62.0
WLSH2_k127_8780186_15 Belongs to the 'phage' integrase family K14059 - - 0.0003108 48.0
WLSH2_k127_8780186_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 521.0
WLSH2_k127_8780186_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 422.0
WLSH2_k127_8780186_4 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 320.0
WLSH2_k127_8780186_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 293.0
WLSH2_k127_8780186_6 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000003252 176.0
WLSH2_k127_8780186_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000004584 128.0
WLSH2_k127_8780186_8 Integrase core domain - - - 0.00000000000000000000000002085 118.0
WLSH2_k127_8780186_9 protein conserved in bacteria - - - 0.000000000000004366 76.0
WLSH2_k127_8822958_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.293e-222 712.0
WLSH2_k127_8822958_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 2.601e-196 621.0
WLSH2_k127_8822958_10 Integrase - - - 0.000007312 51.0
WLSH2_k127_8822958_2 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 393.0
WLSH2_k127_8822958_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004418 256.0
WLSH2_k127_8822958_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000006388 199.0
WLSH2_k127_8822958_5 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000005012 181.0
WLSH2_k127_8822958_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000001725 178.0
WLSH2_k127_8822958_7 EcsC protein family - - - 0.00000000000000000000000000000000000000000006726 162.0
WLSH2_k127_8822958_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.000000000000000006831 88.0
WLSH2_k127_8822958_9 SnoaL-like domain - - - 0.0000000000000002313 85.0
WLSH2_k127_8829364_0 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000003827 179.0
WLSH2_k127_8829364_1 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000003524 165.0
WLSH2_k127_8829364_2 YGGT family K02221 - - 0.000000000000000000000000000005433 123.0
WLSH2_k127_8829364_3 regulatory protein, FmdB family - - - 0.0000000000000000007465 92.0
WLSH2_k127_8829364_4 DnaJ molecular chaperone homology domain K05516 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000005855 86.0
WLSH2_k127_8829364_5 Belongs to the pyrroline-5-carboxylate reductase family K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009651,GO:0016491,GO:0016645,GO:0016646,GO:0030312,GO:0044424,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.5.1.2 0.00000000000000121 79.0
WLSH2_k127_8829364_6 Belongs to the UPF0235 family K09131 - - 0.00000000002853 69.0
WLSH2_k127_8829364_7 overlaps another CDS with the same product name - - - 0.0000000001068 71.0
WLSH2_k127_8902182_0 3-demethylubiquinone-9 3-O-methyltransferase activity K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 341.0
WLSH2_k127_8902182_1 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000004568 255.0
WLSH2_k127_8902182_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000001436 106.0
WLSH2_k127_8902182_3 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000002118 73.0
WLSH2_k127_8902182_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000002135 52.0
WLSH2_k127_8903178_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 557.0
WLSH2_k127_8903178_1 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 539.0
WLSH2_k127_8903178_10 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000008827 126.0
WLSH2_k127_8903178_11 3-phytase K01083 - 3.1.3.8 0.000000000001222 82.0
WLSH2_k127_8903178_12 Calcineurin-like phosphoesterase - - - 0.0000000002322 74.0
WLSH2_k127_8903178_2 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
WLSH2_k127_8903178_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 376.0
WLSH2_k127_8903178_4 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 304.0
WLSH2_k127_8903178_5 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006639 278.0
WLSH2_k127_8903178_7 arylsulfatase A - - - 0.000000000000000000000000000000000000006234 162.0
WLSH2_k127_8903178_9 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000000000000002962 124.0
WLSH2_k127_895695_0 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 6.656e-238 753.0
WLSH2_k127_895695_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 2.281e-227 733.0
WLSH2_k127_895695_10 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003111 264.0
WLSH2_k127_895695_11 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000033 264.0
WLSH2_k127_895695_12 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000006382 216.0
WLSH2_k127_895695_13 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000001371 211.0
WLSH2_k127_895695_14 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000001954 211.0
WLSH2_k127_895695_15 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000002735 169.0
WLSH2_k127_895695_16 nuclease activity K07062 - - 0.0000000000000000000000000000000000000000002402 163.0
WLSH2_k127_895695_17 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000004983 155.0
WLSH2_k127_895695_18 phosphomevalonate kinase K00938 - 2.7.4.2 0.000000000000000000000000000000000001827 152.0
WLSH2_k127_895695_19 - - - - 0.00000000000000000000000003902 110.0
WLSH2_k127_895695_2 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 441.0
WLSH2_k127_895695_20 Nucleoid-structuring protein H-NS K01666 - 4.1.3.39 0.0000000000004585 70.0
WLSH2_k127_895695_23 PIN domain K07062 - - 0.0001568 48.0
WLSH2_k127_895695_3 Enoyl-CoA hydratase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 424.0
WLSH2_k127_895695_4 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 376.0
WLSH2_k127_895695_5 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 358.0
WLSH2_k127_895695_6 synthase K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 347.0
WLSH2_k127_895695_7 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 318.0
WLSH2_k127_895695_8 ergosterol biosynthetic process K02291,K21679 - 2.5.1.32,2.5.1.99,4.2.3.156 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 296.0
WLSH2_k127_895695_9 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000006073 273.0
WLSH2_k127_9008797_0 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 5.56e-208 661.0
WLSH2_k127_9008797_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 577.0
WLSH2_k127_9008797_10 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000006032 163.0
WLSH2_k127_9008797_11 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000659 146.0
WLSH2_k127_9008797_12 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000024 120.0
WLSH2_k127_9008797_13 PHB/PHA accumulation regulator DNA-binding domain - - - 0.00000000000000000000000004793 114.0
WLSH2_k127_9008797_14 - - - - 0.000000000001283 73.0
WLSH2_k127_9008797_16 - - - - 0.000005323 51.0
WLSH2_k127_9008797_17 pilus assembly protein PilW - - - 0.00008862 53.0
WLSH2_k127_9008797_18 COG4970 Tfp pilus assembly protein FimT K08084,K08085 - - 0.0006945 49.0
WLSH2_k127_9008797_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 480.0
WLSH2_k127_9008797_3 PFAM PSP1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001489 269.0
WLSH2_k127_9008797_4 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000277 267.0
WLSH2_k127_9008797_5 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
WLSH2_k127_9008797_6 Asparaginase K01424,K01444,K13051 - 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000004097 260.0
WLSH2_k127_9008797_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000001661 207.0
WLSH2_k127_9008797_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000001659 169.0
WLSH2_k127_9008797_9 serine-type endopeptidase activity K04691,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000006981 168.0
WLSH2_k127_9040760_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 8.918e-224 715.0
WLSH2_k127_9040760_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 531.0
WLSH2_k127_9040760_10 - - - - 0.00001184 51.0
WLSH2_k127_9040760_2 Pyruvate ferredoxin oxidoreductase and related K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 433.0
WLSH2_k127_9040760_3 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 292.0
WLSH2_k127_9040760_4 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000001302 203.0
WLSH2_k127_9040760_5 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000001408 201.0
WLSH2_k127_9040760_6 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000000000000000000000008867 182.0
WLSH2_k127_9040760_7 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000009982 162.0
WLSH2_k127_9040760_8 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000000000002342 141.0
WLSH2_k127_9040760_9 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000009543 84.0
WLSH2_k127_905776_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1040.0
WLSH2_k127_905776_1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 1.405e-223 701.0
WLSH2_k127_905776_2 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 486.0
WLSH2_k127_905776_3 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.000000000000000000000000000000002097 133.0
WLSH2_k127_9078884_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 7.532e-206 649.0
WLSH2_k127_9078884_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 7.08e-198 628.0
WLSH2_k127_9078884_10 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001601 260.0
WLSH2_k127_9078884_11 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000003291 229.0
WLSH2_k127_9078884_12 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000007102 222.0
WLSH2_k127_9078884_13 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000181 223.0
WLSH2_k127_9078884_14 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000000001022 164.0
WLSH2_k127_9078884_15 domain, Protein - - - 0.00000000000000000000000001251 124.0
WLSH2_k127_9078884_16 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000001944 102.0
WLSH2_k127_9078884_17 Proline-rich nuclear receptor coactivator motif - - - 0.0005303 44.0
WLSH2_k127_9078884_2 Pyruvate formate lyase-like K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 598.0
WLSH2_k127_9078884_3 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 449.0
WLSH2_k127_9078884_4 HMGL-like K01666 - 4.1.3.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 400.0
WLSH2_k127_9078884_5 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 399.0
WLSH2_k127_9078884_6 3-hydroxyacyl-CoA dehydrogenase NAD-binding K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 324.0
WLSH2_k127_9078884_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 305.0
WLSH2_k127_9078884_8 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008261 282.0
WLSH2_k127_9078884_9 Phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007382 272.0
WLSH2_k127_9092148_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000173 265.0
WLSH2_k127_9092148_2 nuclear chromosome segregation - - - 0.00000000000000000000000000000003442 134.0
WLSH2_k127_9092148_3 nucleic acid-binding protein, contains PIN domain - - - 0.000000000000000004665 89.0
WLSH2_k127_9092148_5 spermidine synthase activity - - - 0.00000001803 58.0
WLSH2_k127_9135912_0 phosphatidylcholine synthase K01004 - 2.7.8.24 0.00000000000000000000000000000000000000000000000000000002689 207.0
WLSH2_k127_9135912_1 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000002904 160.0
WLSH2_k127_9135912_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000005584 83.0
WLSH2_k127_9135912_4 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000001735 85.0
WLSH2_k127_9135912_5 Transcriptional regulator K03577 - - 0.0000000000001107 79.0
WLSH2_k127_9135912_6 Transcription factor zinc-finger K09981 - - 0.00000004244 61.0
WLSH2_k127_9135912_7 NeuB family K03856 - 2.5.1.54 0.00004342 49.0
WLSH2_k127_9135912_8 Putative transmembrane protein (PGPGW) - - - 0.0006324 48.0
WLSH2_k127_9190679_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.628e-300 942.0
WLSH2_k127_9190679_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 457.0
WLSH2_k127_9190679_10 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000005067 75.0
WLSH2_k127_9190679_11 thiamine diphosphate biosynthetic process K03154 - - 0.000000859 55.0
WLSH2_k127_9190679_12 - - - - 0.0008026 49.0
WLSH2_k127_9190679_2 Mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 323.0
WLSH2_k127_9190679_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 334.0
WLSH2_k127_9190679_4 Belongs to the TtcA family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 310.0
WLSH2_k127_9190679_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004067 252.0
WLSH2_k127_9190679_6 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016426,GO:0016429,GO:0016740,GO:0016741,GO:0030488,GO:0031515,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000001276 242.0
WLSH2_k127_9190679_7 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000001357 169.0
WLSH2_k127_9190679_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000007551 162.0
WLSH2_k127_9190679_9 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000003199 139.0
WLSH2_k127_9257746_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4,1.8.5.3 1.44e-251 807.0
WLSH2_k127_9257746_1 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 455.0
WLSH2_k127_9257746_11 AbrB family - - - 0.00000731 51.0
WLSH2_k127_9257746_12 Nucleotidyltransferase domain - - - 0.00007774 45.0
WLSH2_k127_9257746_2 4Fe-4S dicluster domain K17048,K17051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 443.0
WLSH2_k127_9257746_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 286.0
WLSH2_k127_9257746_4 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000005756 206.0
WLSH2_k127_9257746_5 DJ-1 family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000726 170.0
WLSH2_k127_9257746_6 PIN domain - - - 0.0000000000000000000000000001493 120.0
WLSH2_k127_9257746_7 PIN domain - - - 0.000000000000000000000000001372 116.0
WLSH2_k127_9257746_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000308 79.0
WLSH2_k127_9257746_9 positive regulation of growth - - - 0.0000000000189 71.0
WLSH2_k127_9315942_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 379.0
WLSH2_k127_9315942_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 331.0
WLSH2_k127_9315942_10 Ribosomal proteins 50S L24/mitochondrial 39S L24 K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000006283 134.0
WLSH2_k127_9315942_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000007999 110.0
WLSH2_k127_9315942_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002458 109.0
WLSH2_k127_9315942_13 Elongation factor Tu C-terminal domain K02358 - - 0.0000000000000000002726 87.0
WLSH2_k127_9315942_14 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000001144 58.0
WLSH2_k127_9315942_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000287 260.0
WLSH2_k127_9315942_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000714 225.0
WLSH2_k127_9315942_4 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000001292 214.0
WLSH2_k127_9315942_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000043 206.0
WLSH2_k127_9315942_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000553 190.0
WLSH2_k127_9315942_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000003191 171.0
WLSH2_k127_9315942_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000001094 148.0
WLSH2_k127_9315942_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000002943 145.0
WLSH2_k127_935924_0 acetolactate synthase K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 4.742e-253 794.0
WLSH2_k127_935924_1 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000003213 106.0
WLSH2_k127_935924_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000186 69.0
WLSH2_k127_935924_3 deoxyhypusine monooxygenase activity - - - 0.0002437 51.0
WLSH2_k127_935924_4 Helix-turn-helix XRE-family like proteins - - - 0.0003677 49.0
WLSH2_k127_9400153_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 423.0
WLSH2_k127_9400153_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000002078 250.0
WLSH2_k127_9450915_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 505.0
WLSH2_k127_9450915_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 366.0
WLSH2_k127_9450915_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000009464 131.0
WLSH2_k127_9450915_3 rod shape-determining protein MreD K03571 - - 0.00000009611 60.0
WLSH2_k127_9488395_0 Catalase K03781 - 1.11.1.6 1.389e-291 900.0
WLSH2_k127_9488395_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.102e-228 717.0
WLSH2_k127_9488395_10 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 498.0
WLSH2_k127_9488395_11 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 497.0
WLSH2_k127_9488395_12 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 481.0
WLSH2_k127_9488395_13 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 463.0
WLSH2_k127_9488395_14 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 411.0
WLSH2_k127_9488395_15 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 409.0
WLSH2_k127_9488395_16 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 402.0
WLSH2_k127_9488395_17 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 390.0
WLSH2_k127_9488395_18 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 387.0
WLSH2_k127_9488395_19 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 355.0
WLSH2_k127_9488395_2 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 9.672e-227 718.0
WLSH2_k127_9488395_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 355.0
WLSH2_k127_9488395_21 cytochrome p450 K16046 - 1.14.13.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 347.0
WLSH2_k127_9488395_22 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 323.0
WLSH2_k127_9488395_23 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 310.0
WLSH2_k127_9488395_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10909,K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 304.0
WLSH2_k127_9488395_25 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001116 305.0
WLSH2_k127_9488395_26 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003689 279.0
WLSH2_k127_9488395_27 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000006657 241.0
WLSH2_k127_9488395_28 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000006905 236.0
WLSH2_k127_9488395_29 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000000000000000000000003283 199.0
WLSH2_k127_9488395_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K18501 - - 1.121e-224 707.0
WLSH2_k127_9488395_30 CGGC - - - 0.00000000000000000000000000000000000000000000000000002459 191.0
WLSH2_k127_9488395_31 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000000000000000002998 164.0
WLSH2_k127_9488395_32 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000009262 162.0
WLSH2_k127_9488395_33 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000000000001738 173.0
WLSH2_k127_9488395_34 nitrate reductase activity - - - 0.0000000000000000000000000000000000000001766 159.0
WLSH2_k127_9488395_35 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000001939 148.0
WLSH2_k127_9488395_36 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000008359 146.0
WLSH2_k127_9488395_37 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000001942 140.0
WLSH2_k127_9488395_38 PFAM response regulator receiver - - - 0.00000000000000000000000000000000008667 137.0
WLSH2_k127_9488395_39 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.0000000000000000000000000000000005856 136.0
WLSH2_k127_9488395_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 7.992e-215 674.0
WLSH2_k127_9488395_40 PFAM response regulator receiver - - - 0.0000000000000000000000000000000006967 134.0
WLSH2_k127_9488395_41 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000003291 130.0
WLSH2_k127_9488395_42 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000008296 120.0
WLSH2_k127_9488395_43 Family of unknown function (DUF5320) - - - 0.0000000000000000000000001064 112.0
WLSH2_k127_9488395_44 cheY-homologous receiver domain - - - 0.000000000000000000000000116 110.0
WLSH2_k127_9488395_45 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000002524 112.0
WLSH2_k127_9488395_46 Phospholipid methyltransferase - - - 0.00000000000000000000001958 106.0
WLSH2_k127_9488395_47 transcriptional regulator - - - 0.00000000000000000000003277 105.0
WLSH2_k127_9488395_48 ester cyclase - - - 0.000000000000000000000284 102.0
WLSH2_k127_9488395_49 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000001174 100.0
WLSH2_k127_9488395_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 619.0
WLSH2_k127_9488395_50 PFAM response regulator receiver - - - 0.00000000000000000004983 105.0
WLSH2_k127_9488395_51 DsrE/DsrF-like family - - - 0.000000000000000000831 90.0
WLSH2_k127_9488395_53 Putative regulatory protein - - - 0.0000000000000000577 82.0
WLSH2_k127_9488395_54 cheY-homologous receiver domain - - - 0.00000000000001521 78.0
WLSH2_k127_9488395_55 Divergent 4Fe-4S mono-cluster K05337 - - 0.0000000000004933 70.0
WLSH2_k127_9488395_56 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000001422 70.0
WLSH2_k127_9488395_57 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000002118 63.0
WLSH2_k127_9488395_58 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000009875 73.0
WLSH2_k127_9488395_6 PFAM Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 600.0
WLSH2_k127_9488395_60 PFAM Transcriptional regulator, histidine kinase sensor - - - 0.0000000806 60.0
WLSH2_k127_9488395_61 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0000006355 52.0
WLSH2_k127_9488395_62 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00004129 48.0
WLSH2_k127_9488395_7 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 561.0
WLSH2_k127_9488395_8 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 535.0
WLSH2_k127_9488395_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 506.0
WLSH2_k127_9574799_0 GTP-binding protein TypA K06207 - - 1.9e-205 652.0
WLSH2_k127_9574799_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 369.0
WLSH2_k127_9574799_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000001372 146.0
WLSH2_k127_9574799_3 Luciferase-like monooxygenase - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000002431 76.0
WLSH2_k127_9638217_0 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 329.0
WLSH2_k127_9638217_1 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002574 273.0
WLSH2_k127_9638217_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000001102 163.0
WLSH2_k127_9638217_4 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000003547 156.0
WLSH2_k127_9638217_5 Integrase - - - 0.000000009729 57.0
WLSH2_k127_9638217_6 EF-hand domain - - - 0.0000003536 60.0
WLSH2_k127_9638217_7 Cold shock K03704 - - 0.00001681 48.0
WLSH2_k127_9638217_8 pentaerythritol trinitrate reductase activity K00219,K01069 - 1.3.1.34,3.1.2.6 0.00002032 48.0
WLSH2_k127_9638217_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0005997 43.0
WLSH2_k127_9670380_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 552.0
WLSH2_k127_9670380_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 457.0
WLSH2_k127_9670380_2 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 402.0
WLSH2_k127_9670380_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004902 285.0
WLSH2_k127_9670380_4 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002386 279.0
WLSH2_k127_9670380_5 lysine 2,3-aminomutase - - - 0.0000000000002875 71.0
WLSH2_k127_9686052_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 6.295e-310 964.0
WLSH2_k127_9686052_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 6.769e-216 687.0
WLSH2_k127_9686052_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009887 281.0
WLSH2_k127_9686052_3 PFAM 4Fe-4S K00196,K05796 - - 0.00000000000000000000000006644 112.0
WLSH2_k127_9686052_4 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00007549 48.0
WLSH2_k127_9765522_0 COG0318, Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0 1249.0
WLSH2_k127_9765522_1 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000000000000000002749 212.0
WLSH2_k127_9779223_0 Carboxyl transferase domain - - - 1.01e-255 797.0
WLSH2_k127_9779223_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
WLSH2_k127_9779223_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 349.0
WLSH2_k127_9779223_3 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000000000002003 142.0
WLSH2_k127_9779223_4 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000002774 79.0
WLSH2_k127_9779223_5 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0000000000005425 80.0
WLSH2_k127_9779223_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000001096 65.0
WLSH2_k127_9779223_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000003413 53.0
WLSH2_k127_9779223_8 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00006735 46.0
WLSH2_k127_980077_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 415.0
WLSH2_k127_980077_1 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000009652 198.0
WLSH2_k127_980077_2 isoprenoid biosynthetic process K00805,K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000005692 198.0
WLSH2_k127_980077_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000007513 141.0
WLSH2_k127_980077_4 GtrA-like protein K00995 - 2.7.8.5 0.0000000000000000000000000001197 124.0
WLSH2_k127_9834373_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 607.0
WLSH2_k127_9834373_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 547.0
WLSH2_k127_9834373_2 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 430.0
WLSH2_k127_9834373_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 427.0
WLSH2_k127_9834373_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 359.0
WLSH2_k127_9834373_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 327.0
WLSH2_k127_9834373_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 312.0
WLSH2_k127_9834373_7 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000001349 244.0
WLSH2_k127_9834373_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000007694 157.0
WLSH2_k127_9935990_0 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 299.0
WLSH2_k127_9935990_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000006426 242.0
WLSH2_k127_9935990_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000005441 240.0
WLSH2_k127_9935990_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000219 186.0
WLSH2_k127_9935990_4 NmrA-like family - - - 0.0000000000000000000000000000000000000000000002863 190.0
WLSH2_k127_9935990_5 Formyl transferase - - - 0.000000000000000000000000000000000000000000001138 175.0
WLSH2_k127_9935990_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000004761 166.0
WLSH2_k127_9935990_7 ATP-grasp domain K01955 - 6.3.5.5 0.000000000000000000000000000000000000001955 158.0
WLSH2_k127_9935990_8 chain length determinant protein - - - 0.0000006218 62.0
WLSH2_k127_9935990_9 O-Antigen ligase K18814 - - 0.0001167 55.0
WLSH2_k127_9985906_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 445.0
WLSH2_k127_9985906_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 449.0
WLSH2_k127_9985906_2 phosphorelay signal transduction system K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 316.0
WLSH2_k127_9985906_3 Acyl-CoA dehydrogenase type 2 domain - - - 0.000000000000000000257 89.0
WLSH2_k127_9992265_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.817e-201 642.0
WLSH2_k127_9992265_1 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
WLSH2_k127_9992265_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000006108 170.0
WLSH2_k127_9992265_3 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.0000000000000000000000000001593 128.0
WLSH2_k127_9992265_4 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000003788 63.0