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Overview

ID MAG04219
Name WLSH2_bin.51
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rickettsiales
Family UBA6187
Genus 1-14-0-20-39-49
Species
Assembly information
Completeness (%) 91.43
Contamination (%) 0.06
GC content (%) 50.0
N50 (bp) 42,669
Genome size (bp) 1,976,343

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1634

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10048888_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 1.644e-271 842.0
WLSH2_k127_10048888_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 2.789e-222 700.0
WLSH2_k127_10048888_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 406.0
WLSH2_k127_10048888_11 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 363.0
WLSH2_k127_10048888_12 Cytochrome c oxidase subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 357.0
WLSH2_k127_10048888_13 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 352.0
WLSH2_k127_10048888_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 302.0
WLSH2_k127_10048888_15 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 293.0
WLSH2_k127_10048888_16 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000001685 235.0
WLSH2_k127_10048888_17 SURF1 family K14998 GO:0006996,GO:0007005,GO:0008150,GO:0008535,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0033108,GO:0033617,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000001423 205.0
WLSH2_k127_10048888_18 Cytochrome c oxidase assembly protein CtaG/Cox11 K02258 - - 0.000000000000000000000000000000000000000000000000000007493 194.0
WLSH2_k127_10048888_19 CHASE domain - - - 0.0000000000000000000000000000000000000000000008495 192.0
WLSH2_k127_10048888_2 citrate synthase K01647 - 2.3.3.1 2.109e-211 666.0
WLSH2_k127_10048888_20 Peptidase family M23 - - - 0.000000000000000000000000000000000000000002337 169.0
WLSH2_k127_10048888_21 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001987 115.0
WLSH2_k127_10048888_22 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000007615 115.0
WLSH2_k127_10048888_23 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000000000000000001761 121.0
WLSH2_k127_10048888_24 Protein of unknown function (DUF983) - - - 0.00000000000000000000000001495 112.0
WLSH2_k127_10048888_25 PFAM PIN domain - - - 0.000000000000000000000000803 108.0
WLSH2_k127_10048888_26 MerR HTH family regulatory protein - - - 0.000000000000000000000001963 110.0
WLSH2_k127_10048888_27 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000005143 84.0
WLSH2_k127_10048888_28 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000001139 76.0
WLSH2_k127_10048888_29 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000001151 68.0
WLSH2_k127_10048888_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 612.0
WLSH2_k127_10048888_30 Histidine kinase K20972 - - 0.00001289 53.0
WLSH2_k127_10048888_31 Transcriptional regulator - - - 0.0009594 44.0
WLSH2_k127_10048888_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 601.0
WLSH2_k127_10048888_5 Threonine synthase K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 593.0
WLSH2_k127_10048888_6 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 563.0
WLSH2_k127_10048888_7 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 499.0
WLSH2_k127_10048888_8 Histidine Phosphotransfer domain K02488,K11443 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 517.0
WLSH2_k127_10048888_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 448.0
WLSH2_k127_10081443_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 485.0
WLSH2_k127_10081443_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 389.0
WLSH2_k127_10081443_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 295.0
WLSH2_k127_10081443_3 transcriptional - - - 0.000000000000000000000000000000000001048 143.0
WLSH2_k127_10081443_4 Uncharacterised protein family (UPF0262) - - - 0.0000000000000000000000000001551 121.0
WLSH2_k127_10081443_5 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000002282 100.0
WLSH2_k127_10099042_0 Belongs to the ABC transporter superfamily K13896 - - 8.335e-201 638.0
WLSH2_k127_10099042_1 single-stranded-DNA-specific exonuclease recJ K07462 - - 1.14e-198 636.0
WLSH2_k127_10099042_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000005924 214.0
WLSH2_k127_10099042_11 Belongs to the peptidase S8 family K01342 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030193,GO:0030195,GO:0032101,GO:0032102,GO:0042730,GO:0043170,GO:0044238,GO:0048519,GO:0048583,GO:0048585,GO:0050789,GO:0050818,GO:0050819,GO:0050878,GO:0051239,GO:0051241,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070011,GO:0071704,GO:0080134,GO:0140096,GO:1900046,GO:1900047,GO:1901564,GO:1903034,GO:1903035 3.4.21.62 0.00000000000000000000000000000000000000000000000000003833 214.0
WLSH2_k127_10099042_12 acetyltransferase K15520 - 2.3.1.189 0.0000000000000000000000000000000000000002834 155.0
WLSH2_k127_10099042_13 response regulator receiver K03413 - - 0.0000000000000000000000000000000000000004083 152.0
WLSH2_k127_10099042_14 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000000000000001134 106.0
WLSH2_k127_10099042_15 Protein of unknown function (DUF1778) - - - 0.00000005643 58.0
WLSH2_k127_10099042_16 positive regulation of catalytic activity in other organism involved in symbiotic interaction K07151,K19870 - 2.4.99.18 0.00003772 55.0
WLSH2_k127_10099042_2 Aminotransferase class I and II K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 581.0
WLSH2_k127_10099042_3 His Kinase A (phosphoacceptor) domain K13587 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 545.0
WLSH2_k127_10099042_4 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 481.0
WLSH2_k127_10099042_5 Homoserine dehydrogenase K00003 GO:0003674,GO:0003824,GO:0004412,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 481.0
WLSH2_k127_10099042_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005512 266.0
WLSH2_k127_10099042_7 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
WLSH2_k127_10099042_8 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000001113 240.0
WLSH2_k127_10099042_9 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000003135 228.0
WLSH2_k127_10164970_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 579.0
WLSH2_k127_10164970_1 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 470.0
WLSH2_k127_10164970_10 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000007538 137.0
WLSH2_k127_10164970_11 transcriptional - - - 0.000000000000000000000000003736 115.0
WLSH2_k127_10164970_12 Belongs to the ompA family - - - 0.0000000000000000000000001172 117.0
WLSH2_k127_10164970_13 COG2913 Small protein A (tmRNA-binding) - - - 0.0000000000000000000002126 104.0
WLSH2_k127_10164970_14 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000001034 89.0
WLSH2_k127_10164970_15 - - - - 0.000000000000000004715 90.0
WLSH2_k127_10164970_17 - - - - 0.000000000001381 69.0
WLSH2_k127_10164970_18 - - - - 0.00000000002171 71.0
WLSH2_k127_10164970_19 PAS domain - - - 0.0000000006324 66.0
WLSH2_k127_10164970_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 403.0
WLSH2_k127_10164970_20 Peptidase C26 K07010 - - 0.000000003727 68.0
WLSH2_k127_10164970_22 sequence-specific DNA binding K01356 - 3.4.21.88 0.000104 48.0
WLSH2_k127_10164970_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 378.0
WLSH2_k127_10164970_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 332.0
WLSH2_k127_10164970_5 RNA polymerase sigma factor K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 313.0
WLSH2_k127_10164970_6 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 323.0
WLSH2_k127_10164970_7 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 292.0
WLSH2_k127_10164970_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000127 284.0
WLSH2_k127_10164970_9 - - - - 0.0000000000000000000000000000000000000001173 155.0
WLSH2_k127_10197361_0 Heat shock 70 kDa protein K04043 - - 1.048e-306 951.0
WLSH2_k127_10197361_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.671e-294 916.0
WLSH2_k127_10197361_10 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 410.0
WLSH2_k127_10197361_11 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 372.0
WLSH2_k127_10197361_12 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 GO:0003674,GO:0003824,GO:0006082,GO:0006090,GO:0008150,GO:0008152,GO:0008840,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044281,GO:0071704 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 370.0
WLSH2_k127_10197361_13 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 336.0
WLSH2_k127_10197361_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023,K00059 - 1.1.1.100,1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 302.0
WLSH2_k127_10197361_15 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 294.0
WLSH2_k127_10197361_16 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 296.0
WLSH2_k127_10197361_17 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002218 274.0
WLSH2_k127_10197361_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 277.0
WLSH2_k127_10197361_19 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036308,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000559 272.0
WLSH2_k127_10197361_2 isocitrate K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 586.0
WLSH2_k127_10197361_20 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000535 256.0
WLSH2_k127_10197361_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000567 244.0
WLSH2_k127_10197361_22 carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000001306 233.0
WLSH2_k127_10197361_23 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000000000000000000000000000000002251 219.0
WLSH2_k127_10197361_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000409 193.0
WLSH2_k127_10197361_25 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000003217 190.0
WLSH2_k127_10197361_26 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000002436 182.0
WLSH2_k127_10197361_27 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000002891 180.0
WLSH2_k127_10197361_28 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000006769 180.0
WLSH2_k127_10197361_29 COG0593 ATPase involved in DNA replication initiation - - - 0.0000000000000000000000000000000000000000003651 166.0
WLSH2_k127_10197361_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 558.0
WLSH2_k127_10197361_30 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000000002546 138.0
WLSH2_k127_10197361_31 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000007774 119.0
WLSH2_k127_10197361_32 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000005558 106.0
WLSH2_k127_10197361_33 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000268 105.0
WLSH2_k127_10197361_34 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.0000000000000000000001266 107.0
WLSH2_k127_10197361_35 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000000000000000007736 98.0
WLSH2_k127_10197361_36 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.00000000000000000008667 102.0
WLSH2_k127_10197361_37 Type IV leader peptidase family K02654 - 3.4.23.43 0.000000000000000004206 94.0
WLSH2_k127_10197361_38 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000004089 80.0
WLSH2_k127_10197361_39 implicated in regulation of membrane protease activity - - - 0.0000000000000006731 84.0
WLSH2_k127_10197361_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 479.0
WLSH2_k127_10197361_40 PAS domain - - - 0.000000000000001185 83.0
WLSH2_k127_10197361_41 Prokaryotic N-terminal methylation motif - - - 0.0000000000000166 83.0
WLSH2_k127_10197361_42 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000002812 64.0
WLSH2_k127_10197361_43 succinate dehydrogenase K00242 - - 0.00000003208 59.0
WLSH2_k127_10197361_44 succinate dehydrogenase K00241 - - 0.000002731 53.0
WLSH2_k127_10197361_45 ERAD pathway - - - 0.000004894 60.0
WLSH2_k127_10197361_5 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 480.0
WLSH2_k127_10197361_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 472.0
WLSH2_k127_10197361_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 458.0
WLSH2_k127_10197361_8 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 450.0
WLSH2_k127_10197361_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 422.0
WLSH2_k127_10280692_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1491.0
WLSH2_k127_10280692_1 FAD dependent oxidoreductase K07137 - - 1.26e-290 898.0
WLSH2_k127_10280692_10 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 553.0
WLSH2_k127_10280692_11 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 517.0
WLSH2_k127_10280692_12 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 514.0
WLSH2_k127_10280692_13 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 509.0
WLSH2_k127_10280692_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 485.0
WLSH2_k127_10280692_15 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 468.0
WLSH2_k127_10280692_16 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 452.0
WLSH2_k127_10280692_17 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 430.0
WLSH2_k127_10280692_18 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 411.0
WLSH2_k127_10280692_19 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 382.0
WLSH2_k127_10280692_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 2.866e-272 859.0
WLSH2_k127_10280692_20 AFG1-like ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 382.0
WLSH2_k127_10280692_21 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 370.0
WLSH2_k127_10280692_22 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 355.0
WLSH2_k127_10280692_23 bacterial-type flagellum assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 344.0
WLSH2_k127_10280692_24 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 315.0
WLSH2_k127_10280692_25 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 306.0
WLSH2_k127_10280692_26 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 306.0
WLSH2_k127_10280692_27 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 302.0
WLSH2_k127_10280692_28 FAD linked oxidase domain protein K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 310.0
WLSH2_k127_10280692_29 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 300.0
WLSH2_k127_10280692_3 Belongs to the UbiD family K03182 - 4.1.1.98 3.689e-271 840.0
WLSH2_k127_10280692_30 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007614 278.0
WLSH2_k127_10280692_31 chorismate binding enzyme K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001669 288.0
WLSH2_k127_10280692_32 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 275.0
WLSH2_k127_10280692_33 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000002972 263.0
WLSH2_k127_10280692_34 signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002193 260.0
WLSH2_k127_10280692_35 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000002451 223.0
WLSH2_k127_10280692_36 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000006269 216.0
WLSH2_k127_10280692_37 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000002147 226.0
WLSH2_k127_10280692_38 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000006943 216.0
WLSH2_k127_10280692_39 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.00000000000000000000000000000000000000000000000000000000228 203.0
WLSH2_k127_10280692_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.974e-225 711.0
WLSH2_k127_10280692_40 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000000000000000000001571 203.0
WLSH2_k127_10280692_41 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000009405 197.0
WLSH2_k127_10280692_42 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000329 212.0
WLSH2_k127_10280692_43 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000009991 192.0
WLSH2_k127_10280692_44 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000005741 190.0
WLSH2_k127_10280692_45 Fic/DOC family K07341 - - 0.0000000000000000000000000000000000000000000000003808 179.0
WLSH2_k127_10280692_46 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000001088 181.0
WLSH2_k127_10280692_47 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000001528 178.0
WLSH2_k127_10280692_48 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000002599 169.0
WLSH2_k127_10280692_49 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000006266 159.0
WLSH2_k127_10280692_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 5.385e-211 677.0
WLSH2_k127_10280692_50 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000001973 144.0
WLSH2_k127_10280692_51 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000193 139.0
WLSH2_k127_10280692_52 Acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000003469 131.0
WLSH2_k127_10280692_53 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000001788 119.0
WLSH2_k127_10280692_54 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000002033 121.0
WLSH2_k127_10280692_55 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000158 114.0
WLSH2_k127_10280692_57 Belongs to the frataxin family K19054 - 1.16.3.1 0.00000000000000008561 83.0
WLSH2_k127_10280692_58 histidine kinase response regulator K13587 - 2.7.13.3 0.00000000007203 70.0
WLSH2_k127_10280692_59 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000001096 61.0
WLSH2_k127_10280692_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.85e-199 627.0
WLSH2_k127_10280692_61 Pentapeptide repeats (9 copies) - - - 0.00001123 59.0
WLSH2_k127_10280692_7 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 588.0
WLSH2_k127_10280692_8 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 567.0
WLSH2_k127_10280692_9 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 567.0
WLSH2_k127_10438868_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.224e-277 866.0
WLSH2_k127_10438868_1 COG1138 Cytochrome c biogenesis factor K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 551.0
WLSH2_k127_10438868_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000001553 148.0
WLSH2_k127_10438868_11 subunit of a heme lyase K02200 - - 0.00000000000000000000000001122 113.0
WLSH2_k127_10438868_12 Chemotaxis protein cheY K03413 - - 0.0000000000000000000008859 99.0
WLSH2_k127_10438868_13 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000006567 94.0
WLSH2_k127_10438868_14 Ankyrin repeat - - - 0.0000000000000000006505 93.0
WLSH2_k127_10438868_15 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.00000000001159 78.0
WLSH2_k127_10438868_16 Flagellar protein FliS K02422 GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.00008968 50.0
WLSH2_k127_10438868_2 chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 537.0
WLSH2_k127_10438868_3 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 474.0
WLSH2_k127_10438868_4 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 381.0
WLSH2_k127_10438868_5 Quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 347.0
WLSH2_k127_10438868_6 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 325.0
WLSH2_k127_10438868_7 Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000032 293.0
WLSH2_k127_10438868_8 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000005949 170.0
WLSH2_k127_10438868_9 COG0526 Thiol-disulfide isomerase and thioredoxins K02199 - - 0.0000000000000000000000000000000000000000347 158.0
WLSH2_k127_10511672_0 Type IV secretory system Conjugative DNA transfer K03205 - - 1.929e-225 714.0
WLSH2_k127_10511672_1 ATPase, AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 465.0
WLSH2_k127_10511672_10 Transposase - - - 0.0000000000001469 70.0
WLSH2_k127_10511672_11 and ankyrin repeat domains 1 - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005929,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010941,GO:0010942,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031974,GO:0031981,GO:0042981,GO:0042995,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044093,GO:0044422,GO:0044424,GO:0044428,GO:0044441,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051090,GO:0051091,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0060548,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097546,GO:0120025,GO:0120038,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000001769 65.0
WLSH2_k127_10511672_12 IS2 (IS982-family) - - - 0.000001522 51.0
WLSH2_k127_10511672_13 IS2 (IS982-family) - - - 0.00004129 48.0
WLSH2_k127_10511672_15 TIGRFAM cytochrome c oxidase, cbb3-type, subunit I K00404 - 1.9.3.1 0.0004512 44.0
WLSH2_k127_10511672_2 HTH-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 404.0
WLSH2_k127_10511672_3 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 370.0
WLSH2_k127_10511672_4 Protein of unknown function (DUF3363) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 345.0
WLSH2_k127_10511672_5 PFAM type II secretion system protein E K02283,K20527 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 328.0
WLSH2_k127_10511672_6 Subtilase family K08651,K14645 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000506 267.0
WLSH2_k127_10511672_7 Fic/DOC family - - - 0.0000000000000000000000000000000000008347 146.0
WLSH2_k127_10511672_8 Helix-turn-helix domain K07483 - - 0.0000000000000000000000000005094 115.0
WLSH2_k127_10511672_9 copG family - - - 0.0000000000000000005656 93.0
WLSH2_k127_11028171_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1379.0
WLSH2_k127_11028171_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.767e-306 947.0
WLSH2_k127_11028171_10 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 460.0
WLSH2_k127_11028171_11 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 445.0
WLSH2_k127_11028171_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 438.0
WLSH2_k127_11028171_13 NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 426.0
WLSH2_k127_11028171_14 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 426.0
WLSH2_k127_11028171_15 PFAM Cys Met metabolism PLP-dependent enzyme K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 421.0
WLSH2_k127_11028171_16 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 412.0
WLSH2_k127_11028171_17 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 370.0
WLSH2_k127_11028171_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 362.0
WLSH2_k127_11028171_19 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 346.0
WLSH2_k127_11028171_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.526e-306 947.0
WLSH2_k127_11028171_20 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 325.0
WLSH2_k127_11028171_21 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 321.0
WLSH2_k127_11028171_22 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 304.0
WLSH2_k127_11028171_23 ABC-type Mn2 Zn2 transport systems, permease components K09816 GO:0000006,GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0010035,GO:0010038,GO:0010043,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0042221,GO:0044464,GO:0046873,GO:0046915,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 295.0
WLSH2_k127_11028171_24 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 289.0
WLSH2_k127_11028171_25 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009725 284.0
WLSH2_k127_11028171_26 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K06125 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001192 275.0
WLSH2_k127_11028171_27 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000002592 227.0
WLSH2_k127_11028171_28 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000003203 229.0
WLSH2_k127_11028171_29 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000009827 228.0
WLSH2_k127_11028171_3 DNA helicase K03657 - 3.6.4.12 1.738e-259 818.0
WLSH2_k127_11028171_30 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000001231 213.0
WLSH2_k127_11028171_31 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000002402 208.0
WLSH2_k127_11028171_32 COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.0000000000000000000000000000000000000000000000000000000002575 216.0
WLSH2_k127_11028171_34 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000001023 183.0
WLSH2_k127_11028171_35 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000002741 172.0
WLSH2_k127_11028171_36 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000004776 185.0
WLSH2_k127_11028171_37 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 0.000000000000000000000000000000000000000002295 162.0
WLSH2_k127_11028171_38 protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000008403 177.0
WLSH2_k127_11028171_39 ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000000004092 151.0
WLSH2_k127_11028171_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.158e-240 748.0
WLSH2_k127_11028171_40 Ion channel - - - 0.00000000000000000000000000000000000001195 148.0
WLSH2_k127_11028171_41 type IV secretion system protein K03201 - - 0.00000000000000000000000000000000000001552 168.0
WLSH2_k127_11028171_42 Carboxylesterase family - - - 0.00000000000000000000000000000000000009326 154.0
WLSH2_k127_11028171_43 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaD and TsaB. TsaE seems to play an indirect role in the t(6)A biosynthesis pathway, possibly in regulating the core enzymatic function of TsaD (By similarity) K06925 - - 0.0000000000000000000000000000000000002204 145.0
WLSH2_k127_11028171_44 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000005722 132.0
WLSH2_k127_11028171_45 ABC transporter, periplasmic molybdate-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.000000000000000000000000000006486 129.0
WLSH2_k127_11028171_46 type IV secretion system K03201 - - 0.00000000000000000000000000001331 138.0
WLSH2_k127_11028171_48 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000004282 121.0
WLSH2_k127_11028171_49 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000003719 128.0
WLSH2_k127_11028171_5 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.744e-235 750.0
WLSH2_k127_11028171_50 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000005548 113.0
WLSH2_k127_11028171_51 succinate dehydrogenase activity K00242 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000003818 113.0
WLSH2_k127_11028171_52 response regulator - - - 0.000000000000000000001293 104.0
WLSH2_k127_11028171_53 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.00000000000000001357 90.0
WLSH2_k127_11028171_54 PAS domain - - - 0.000000000000004764 81.0
WLSH2_k127_11028171_55 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000001055 85.0
WLSH2_k127_11028171_56 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000005787 73.0
WLSH2_k127_11028171_57 transcriptional - - - 0.0000000001626 70.0
WLSH2_k127_11028171_58 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000002774 52.0
WLSH2_k127_11028171_59 Protein conserved in bacteria - - - 0.000006165 53.0
WLSH2_k127_11028171_6 Molecular chaperone. Has ATPase activity K04079 - - 5.632e-233 736.0
WLSH2_k127_11028171_60 - - - - 0.00001302 55.0
WLSH2_k127_11028171_61 His Kinase A (phosphoacceptor) domain - - - 0.00008369 49.0
WLSH2_k127_11028171_62 helix-turn-helix - - - 0.0004438 47.0
WLSH2_k127_11028171_63 PAS domain - - - 0.0005671 49.0
WLSH2_k127_11028171_7 cysteinyl-tRNA aminoacylation K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 542.0
WLSH2_k127_11028171_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 538.0
WLSH2_k127_11028171_9 PAS PAC domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 536.0
WLSH2_k127_111373_0 GTA TIM-barrel-like domain - - - 0.0 1150.0
WLSH2_k127_111373_1 oligoendopeptidase F K08602 - - 2.723e-228 721.0
WLSH2_k127_111373_10 - - - - 0.00000000000000000000000000000000003591 156.0
WLSH2_k127_111373_12 - - - - 0.0000000000000001138 85.0
WLSH2_k127_111373_14 Hypoxia induced protein conserved region - - - 0.000000005963 58.0
WLSH2_k127_111373_17 Predicted membrane protein (DUF2335) - - - 0.00001093 54.0
WLSH2_k127_111373_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 586.0
WLSH2_k127_111373_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 424.0
WLSH2_k127_111373_4 Electron transfer flavoprotein FAD-binding domain K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 400.0
WLSH2_k127_111373_5 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
WLSH2_k127_111373_6 Phage conserved hypothetical protein BR0599 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009957 278.0
WLSH2_k127_111373_7 Glycoside hydrolase family 24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006779 251.0
WLSH2_k127_111373_8 Protein of unknown function (DUF2793) - - - 0.000000000000000000000000000000000000000000006346 188.0
WLSH2_k127_111373_9 NLP P60 protein - - - 0.000000000000000000000000000000000008204 141.0
WLSH2_k127_11260349_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 8.703e-308 951.0
WLSH2_k127_11260349_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.94e-230 722.0
WLSH2_k127_11260349_2 Nitronate monooxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 484.0
WLSH2_k127_11260349_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 481.0
WLSH2_k127_11260349_4 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 466.0
WLSH2_k127_11260349_5 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 356.0
WLSH2_k127_11260349_6 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002017 279.0
WLSH2_k127_11260349_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001642 169.0
WLSH2_k127_11260349_8 Cold-shock protein K03704 - - 0.00000000000000000000000001349 109.0
WLSH2_k127_11260349_9 Protein conserved in bacteria - - - 0.00002946 51.0
WLSH2_k127_11379795_0 type IV secretion system protein K03199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 579.0
WLSH2_k127_11379795_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 477.0
WLSH2_k127_11379795_10 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 323.0
WLSH2_k127_11379795_11 Mitochondrial fission ELM1 K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
WLSH2_k127_11379795_12 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
WLSH2_k127_11379795_13 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 288.0
WLSH2_k127_11379795_14 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000262 265.0
WLSH2_k127_11379795_15 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000001642 178.0
WLSH2_k127_11379795_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000008491 171.0
WLSH2_k127_11379795_17 - - - - 0.0000000000000000000000000000000000000003205 155.0
WLSH2_k127_11379795_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000994 133.0
WLSH2_k127_11379795_19 - - - - 0.0000000000000000000000001529 120.0
WLSH2_k127_11379795_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 479.0
WLSH2_k127_11379795_20 50S ribosomal protein L31 K02909 - - 0.00000000000000000000001366 102.0
WLSH2_k127_11379795_21 PFAM pentapeptide repeat protein - - - 0.0000000000000000000002329 113.0
WLSH2_k127_11379795_23 PFAM SNARE associated Golgi protein - - - 0.000000000000002692 77.0
WLSH2_k127_11379795_24 Transcriptional regulator - - - 0.000000000000005674 78.0
WLSH2_k127_11379795_25 peptidase activity, acting on L-amino acid peptides - - - 0.0009971 53.0
WLSH2_k127_11379795_3 Transporter associated domain K03699 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 446.0
WLSH2_k127_11379795_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 380.0
WLSH2_k127_11379795_5 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 360.0
WLSH2_k127_11379795_6 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 351.0
WLSH2_k127_11379795_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 342.0
WLSH2_k127_11379795_8 KR domain K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 325.0
WLSH2_k127_11379795_9 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 332.0
WLSH2_k127_1457599_0 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 547.0
WLSH2_k127_1457599_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 351.0
WLSH2_k127_1457599_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000004092 228.0
WLSH2_k127_1457599_3 PFAM OsmC family protein K06889,K07397 - - 0.00000000000000000000000000000000000000004658 157.0
WLSH2_k127_1457599_4 domain protein K02014,K16087,K20276 - - 0.0000000000000000000000000000002845 132.0
WLSH2_k127_1701292_0 poly-beta-hydroxybutyrate polymerase - - - 1.061e-211 674.0
WLSH2_k127_1701292_1 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 608.0
WLSH2_k127_1701292_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 578.0
WLSH2_k127_1701292_3 Universal stress protein family - - - 0.000000000000000000000000000000000000009462 154.0
WLSH2_k127_1701292_4 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000000000000000000000000000000004817 144.0
WLSH2_k127_1701292_5 Resolvase, N terminal domain - - - 0.00000000000000000003649 89.0
WLSH2_k127_1701292_6 Protein required for attachment to host cells - - - 0.000000000001529 73.0
WLSH2_k127_1701292_7 - - - - 0.0000000008023 65.0
WLSH2_k127_1750701_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1186.0
WLSH2_k127_1750701_1 FtsH Extracellular K03798 - - 5.48e-257 808.0
WLSH2_k127_1750701_10 PFAM tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 417.0
WLSH2_k127_1750701_11 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 414.0
WLSH2_k127_1750701_12 Major facilitator K03762 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 417.0
WLSH2_k127_1750701_13 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 392.0
WLSH2_k127_1750701_14 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 380.0
WLSH2_k127_1750701_15 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 345.0
WLSH2_k127_1750701_16 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
WLSH2_k127_1750701_17 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 333.0
WLSH2_k127_1750701_18 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 322.0
WLSH2_k127_1750701_19 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 328.0
WLSH2_k127_1750701_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.446e-222 703.0
WLSH2_k127_1750701_20 S4 RNA-binding domain K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 317.0
WLSH2_k127_1750701_21 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002828 274.0
WLSH2_k127_1750701_22 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003615 274.0
WLSH2_k127_1750701_23 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
WLSH2_k127_1750701_24 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000956 249.0
WLSH2_k127_1750701_25 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000001653 237.0
WLSH2_k127_1750701_26 RNase H K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000002225 228.0
WLSH2_k127_1750701_27 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000007949 222.0
WLSH2_k127_1750701_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000008518 220.0
WLSH2_k127_1750701_29 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000003927 216.0
WLSH2_k127_1750701_3 4Fe-4S dicluster domain - - - 2.306e-196 623.0
WLSH2_k127_1750701_30 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000528 200.0
WLSH2_k127_1750701_31 COG0811 Biopolymer transport proteins K03562 - - 0.000000000000000000000000000000000000000000000000000004565 199.0
WLSH2_k127_1750701_32 - - - - 0.00000000000000000000000000000000000000000000000004887 184.0
WLSH2_k127_1750701_33 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000000000147 174.0
WLSH2_k127_1750701_34 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000001335 164.0
WLSH2_k127_1750701_35 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000001051 163.0
WLSH2_k127_1750701_36 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000002189 164.0
WLSH2_k127_1750701_37 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000000000000000000000000001256 147.0
WLSH2_k127_1750701_38 membrane protein domain - - - 0.000000000000000000000000000003197 125.0
WLSH2_k127_1750701_39 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.00000000000000000000000000000522 121.0
WLSH2_k127_1750701_4 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 546.0
WLSH2_k127_1750701_40 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000002241 126.0
WLSH2_k127_1750701_41 phage envelope protein - - - 0.000000000000000000000000224 111.0
WLSH2_k127_1750701_42 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000003303 118.0
WLSH2_k127_1750701_43 Cell division and transport-associated protein TolA - - - 0.00000000000000000000004915 109.0
WLSH2_k127_1750701_44 - - - - 0.0000000000000000000001896 100.0
WLSH2_k127_1750701_45 Antitoxin component of a toxin-antitoxin (TA) module K18923 - - 0.00000000000000000002752 92.0
WLSH2_k127_1750701_46 protein conserved in bacteria K09806 - - 0.000000007817 60.0
WLSH2_k127_1750701_47 - - - - 0.000009334 55.0
WLSH2_k127_1750701_48 Mitochondrial fission ELM1 K07276 - - 0.000009893 50.0
WLSH2_k127_1750701_49 Protein of unknown function (DUF3108) - - - 0.00003204 55.0
WLSH2_k127_1750701_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 535.0
WLSH2_k127_1750701_6 cobalt chelatase K09883 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 500.0
WLSH2_k127_1750701_7 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 453.0
WLSH2_k127_1750701_8 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 440.0
WLSH2_k127_1750701_9 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 436.0
WLSH2_k127_1753321_0 Dehydratase family K01687 - 4.2.1.9 5.135e-286 889.0
WLSH2_k127_1753321_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 606.0
WLSH2_k127_1753321_10 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000005417 186.0
WLSH2_k127_1753321_11 Pilus assembly protein K02662,K02663 - - 0.000000000000000000000000000000000000000000001509 188.0
WLSH2_k127_1753321_12 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000002075 144.0
WLSH2_k127_1753321_13 Ankyrin repeats (3 copies) - - - 0.0000000000000000000000001457 124.0
WLSH2_k127_1753321_14 Thioredoxin-like - - - 0.00000000000000000000005177 102.0
WLSH2_k127_1753321_15 spectrin binding - - - 0.00000000000003118 87.0
WLSH2_k127_1753321_16 protein conserved in bacteria K09991 - - 0.000000000000581 78.0
WLSH2_k127_1753321_17 - - - - 0.0002609 48.0
WLSH2_k127_1753321_2 Type II/IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008601 443.0
WLSH2_k127_1753321_3 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 432.0
WLSH2_k127_1753321_4 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 375.0
WLSH2_k127_1753321_5 protein N-acetylglucosaminyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 387.0
WLSH2_k127_1753321_6 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 365.0
WLSH2_k127_1753321_7 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 342.0
WLSH2_k127_1753321_8 Bacterial type II/III secretion system short domain K02453,K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 317.0
WLSH2_k127_1753321_9 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000001444 198.0
WLSH2_k127_1847220_0 Type IV secretory system Conjugative DNA transfer K03205 - - 1.498e-222 705.0
WLSH2_k127_1847220_1 Domain of unknown function (DUF4172) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 451.0
WLSH2_k127_1847220_2 PFAM type II secretion system protein E K02283,K20527 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 324.0
WLSH2_k127_1847220_3 Protein of unknown function (DUF3363) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 335.0
WLSH2_k127_1847220_4 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.000000000000000000000005364 104.0
WLSH2_k127_1847220_5 copG family - - - 0.0000000000000006793 83.0
WLSH2_k127_1847220_6 Transcriptional regulator K07726 - - 0.000000000000002413 80.0
WLSH2_k127_2000315_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 6.315e-212 673.0
WLSH2_k127_2000315_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 292.0
WLSH2_k127_2000315_2 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
WLSH2_k127_2000315_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000001519 211.0
WLSH2_k127_2000315_4 Protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.00000000000000000000000000000000003673 146.0
WLSH2_k127_2000315_5 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000004873 119.0
WLSH2_k127_2000315_6 adhesin AidA-related - - - 0.00000000000748 78.0
WLSH2_k127_2000315_7 cellulose binding K01179,K01216,K21449 - 3.2.1.4,3.2.1.73 0.000000127 64.0
WLSH2_k127_2087964_0 Dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0 1459.0
WLSH2_k127_2087964_1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 1.491e-271 856.0
WLSH2_k127_2087964_10 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 482.0
WLSH2_k127_2087964_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 452.0
WLSH2_k127_2087964_12 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 428.0
WLSH2_k127_2087964_13 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 425.0
WLSH2_k127_2087964_14 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 382.0
WLSH2_k127_2087964_15 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 362.0
WLSH2_k127_2087964_16 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 357.0
WLSH2_k127_2087964_17 Peptidase M16 inactive domain K07263,K07623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 357.0
WLSH2_k127_2087964_18 Belongs to the GPI family K01810,K13810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 349.0
WLSH2_k127_2087964_19 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 340.0
WLSH2_k127_2087964_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.918e-243 766.0
WLSH2_k127_2087964_20 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 318.0
WLSH2_k127_2087964_21 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 302.0
WLSH2_k127_2087964_22 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006761 278.0
WLSH2_k127_2087964_23 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004592 275.0
WLSH2_k127_2087964_24 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006351 277.0
WLSH2_k127_2087964_25 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000306 222.0
WLSH2_k127_2087964_26 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000003606 216.0
WLSH2_k127_2087964_27 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000008141 217.0
WLSH2_k127_2087964_28 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000005535 201.0
WLSH2_k127_2087964_29 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000002063 199.0
WLSH2_k127_2087964_3 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.008e-224 712.0
WLSH2_k127_2087964_30 - - - - 0.0000000000000000000000000000000000000000000000000002053 192.0
WLSH2_k127_2087964_31 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000005436 191.0
WLSH2_k127_2087964_32 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000009399 175.0
WLSH2_k127_2087964_33 Rrf2 family K13643 - - 0.00000000000000000000000000000000000000000001382 166.0
WLSH2_k127_2087964_34 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000001905 162.0
WLSH2_k127_2087964_35 Lysine methyltransferase - - - 0.0000000000000000000000000000000000000000117 168.0
WLSH2_k127_2087964_36 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000003978 144.0
WLSH2_k127_2087964_37 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000008107 143.0
WLSH2_k127_2087964_38 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000006993 138.0
WLSH2_k127_2087964_39 - - - - 0.0000000000000000000000000001902 119.0
WLSH2_k127_2087964_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.438e-212 669.0
WLSH2_k127_2087964_40 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000001731 109.0
WLSH2_k127_2087964_41 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000000000000001531 109.0
WLSH2_k127_2087964_42 Protein of unknown function (DUF3035) - - - 0.00000000000000000007383 96.0
WLSH2_k127_2087964_43 Belongs to the ompA family - - - 0.0000000000000000007349 98.0
WLSH2_k127_2087964_44 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000000004071 94.0
WLSH2_k127_2087964_45 Heavy-metal-associated domain - - - 0.000000000000001445 81.0
WLSH2_k127_2087964_46 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000002483 76.0
WLSH2_k127_2087964_47 Pfam:N_methyl_2 - - - 0.00000000000009483 81.0
WLSH2_k127_2087964_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.094e-210 668.0
WLSH2_k127_2087964_6 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.323e-202 643.0
WLSH2_k127_2087964_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 4.452e-200 629.0
WLSH2_k127_2087964_8 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 565.0
WLSH2_k127_2087964_9 Polysaccharide biosynthesis protein K13013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 574.0
WLSH2_k127_222174_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.491e-243 760.0
WLSH2_k127_222174_1 Type I restriction enzyme R Protein K01153 - 3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 332.0
WLSH2_k127_222174_10 Putative DNA-binding domain - - - 0.0000000000000000000000000000000662 134.0
WLSH2_k127_222174_11 Domain of unknown function (DUF2610) - - - 0.000000000000000000000000000001862 122.0
WLSH2_k127_222174_12 invasion associated locus B - - - 0.00000000000000000000000000024 120.0
WLSH2_k127_222174_14 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000211 95.0
WLSH2_k127_222174_15 Integral membrane protein - - - 0.00000000000001932 78.0
WLSH2_k127_222174_16 Alkylated DNA repair protein - - - 0.0000000005776 61.0
WLSH2_k127_222174_2 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 327.0
WLSH2_k127_222174_3 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 298.0
WLSH2_k127_222174_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002149 269.0
WLSH2_k127_222174_5 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497,K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000003599 254.0
WLSH2_k127_222174_6 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000006416 253.0
WLSH2_k127_222174_7 Flavodoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000917 212.0
WLSH2_k127_222174_8 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000703 188.0
WLSH2_k127_222174_9 general secretion pathway protein - - - 0.0000000000000000000000000000000129 141.0
WLSH2_k127_2378408_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 507.0
WLSH2_k127_2378408_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 432.0
WLSH2_k127_2378408_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 300.0
WLSH2_k127_2378408_3 methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006632 277.0
WLSH2_k127_2378408_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
WLSH2_k127_2378408_5 - - - - 0.00000003166 65.0
WLSH2_k127_3321130_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 385.0
WLSH2_k127_3321130_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000002261 125.0
WLSH2_k127_3321130_2 spermatogenesis K21439 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00002699 54.0
WLSH2_k127_3379731_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.11e-233 731.0
WLSH2_k127_3379731_1 Prokaryotic glutathione synthetase, ATP-grasp domain K05844,K14940 - 6.3.2.32 2.61e-221 694.0
WLSH2_k127_3379731_10 Proton-conducting membrane transporter K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 536.0
WLSH2_k127_3379731_11 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 525.0
WLSH2_k127_3379731_12 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 496.0
WLSH2_k127_3379731_13 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 474.0
WLSH2_k127_3379731_14 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 458.0
WLSH2_k127_3379731_15 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 457.0
WLSH2_k127_3379731_16 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 437.0
WLSH2_k127_3379731_17 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 418.0
WLSH2_k127_3379731_18 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 362.0
WLSH2_k127_3379731_19 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 349.0
WLSH2_k127_3379731_2 3-isopropylmalate dehydratase activity K00749,K01702,K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0010035,GO:0010038,GO:0010494,GO:0016053,GO:0016143,GO:0016144,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019748,GO:0019752,GO:0019757,GO:0019758,GO:0019760,GO:0019761,GO:0032991,GO:0035770,GO:0036464,GO:0042221,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0044550,GO:0046394,GO:0046686,GO:0050486,GO:0050896,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1990904 2.4.1.183,4.2.1.33,4.2.1.35 1.239e-220 693.0
WLSH2_k127_3379731_20 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 341.0
WLSH2_k127_3379731_21 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 301.0
WLSH2_k127_3379731_22 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 297.0
WLSH2_k127_3379731_23 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 288.0
WLSH2_k127_3379731_24 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 289.0
WLSH2_k127_3379731_25 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007459 278.0
WLSH2_k127_3379731_26 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004856 279.0
WLSH2_k127_3379731_27 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002012 263.0
WLSH2_k127_3379731_28 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001576 260.0
WLSH2_k127_3379731_29 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
WLSH2_k127_3379731_3 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 9.997e-218 685.0
WLSH2_k127_3379731_30 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000008312 212.0
WLSH2_k127_3379731_31 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000002407 207.0
WLSH2_k127_3379731_32 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000773 173.0
WLSH2_k127_3379731_33 Domain of unknown function (DUF4040) K05566 - - 0.0000000000000000000000000000000000000003478 155.0
WLSH2_k127_3379731_34 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.0000000000000000000000000000000000000005341 153.0
WLSH2_k127_3379731_35 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000000000000000002542 146.0
WLSH2_k127_3379731_36 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000000000253 143.0
WLSH2_k127_3379731_37 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000002595 143.0
WLSH2_k127_3379731_38 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000000000002459 135.0
WLSH2_k127_3379731_39 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000008277 136.0
WLSH2_k127_3379731_4 Glutamine amidotransferase domain K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009536,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 4.402e-213 671.0
WLSH2_k127_3379731_40 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000008683 128.0
WLSH2_k127_3379731_41 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000001569 130.0
WLSH2_k127_3379731_42 protein conserved in bacteria K09931 - - 0.000000000000000000000000003579 118.0
WLSH2_k127_3379731_43 Bacterial PH domain - - - 0.000000000000000000000000007873 116.0
WLSH2_k127_3379731_44 PIN domain - - - 0.000000000000000000000001805 108.0
WLSH2_k127_3379731_45 Na+/H+ ion antiporter subunit K05569 - - 0.000000000000000000000002348 108.0
WLSH2_k127_3379731_46 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000006445 104.0
WLSH2_k127_3379731_47 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000001066 100.0
WLSH2_k127_3379731_48 bond formation protein, DsbB - - - 0.0000000000000000000003721 102.0
WLSH2_k127_3379731_5 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 614.0
WLSH2_k127_3379731_50 colicin V production K03558 - - 0.000000000000000001941 96.0
WLSH2_k127_3379731_51 - - - - 0.0000000000000000136 84.0
WLSH2_k127_3379731_52 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000000004867 83.0
WLSH2_k127_3379731_53 Protein conserved in bacteria - - - 0.000000000000001094 80.0
WLSH2_k127_3379731_54 Zinc-finger domain - - - 0.000000000000001465 78.0
WLSH2_k127_3379731_55 Restriction endonuclease - - - 0.0000000008767 69.0
WLSH2_k127_3379731_56 - - - - 0.000000003175 61.0
WLSH2_k127_3379731_57 - - - - 0.0000003036 64.0
WLSH2_k127_3379731_58 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000003193 56.0
WLSH2_k127_3379731_6 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 620.0
WLSH2_k127_3379731_7 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 589.0
WLSH2_k127_3379731_8 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 564.0
WLSH2_k127_3379731_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 557.0
WLSH2_k127_3380966_0 Sigma-54 interaction domain K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 518.0
WLSH2_k127_3380966_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 434.0
WLSH2_k127_3380966_2 COG1253 Hemolysins and related proteins containing CBS domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001583 262.0
WLSH2_k127_3380966_3 Voltage gated chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000002699 239.0
WLSH2_k127_3380966_4 transcriptional - - - 0.0000000000000000000000000000000000003902 145.0
WLSH2_k127_3380966_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000001416 138.0
WLSH2_k127_3380966_6 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.0000000000000000000000000000003863 124.0
WLSH2_k127_3382011_0 Malic enzyme K00029 - 1.1.1.40 0.0 1106.0
WLSH2_k127_3382011_1 Propionyl-CoA carboxylase alpha K01965 - 6.4.1.3 9.406e-278 868.0
WLSH2_k127_3382011_10 Tetratricopeptide repeat - - - 0.000000000000000000000000001254 128.0
WLSH2_k127_3382011_11 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000004112 98.0
WLSH2_k127_3382011_12 DUF167 K09131 - - 0.000000000000000005086 87.0
WLSH2_k127_3382011_13 Acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000002551 68.0
WLSH2_k127_3382011_14 PAS domain - - - 0.0000000005644 66.0
WLSH2_k127_3382011_2 propionyl-CoA carboxylase beta K01966 - 2.1.3.15,6.4.1.3 2.902e-260 809.0
WLSH2_k127_3382011_3 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 481.0
WLSH2_k127_3382011_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 301.0
WLSH2_k127_3382011_5 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001259 242.0
WLSH2_k127_3382011_6 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000006246 233.0
WLSH2_k127_3382011_7 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000003434 169.0
WLSH2_k127_3382011_8 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000001567 163.0
WLSH2_k127_3382011_9 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000004322 129.0
WLSH2_k127_3402103_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1223.0
WLSH2_k127_3402103_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.986e-226 712.0
WLSH2_k127_3402103_10 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000001306 191.0
WLSH2_k127_3402103_11 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000006958 171.0
WLSH2_k127_3402103_12 Thioredoxin-like - - - 0.00000000000004952 75.0
WLSH2_k127_3402103_13 COG0784 FOG CheY-like receiver - - - 0.00000000003614 70.0
WLSH2_k127_3402103_14 ankyrin repeat-containing protein - - - 0.00000001809 67.0
WLSH2_k127_3402103_15 - - - - 0.0001952 50.0
WLSH2_k127_3402103_16 response to abiotic stimulus - - - 0.0002662 52.0
WLSH2_k127_3402103_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 445.0
WLSH2_k127_3402103_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 400.0
WLSH2_k127_3402103_4 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 363.0
WLSH2_k127_3402103_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 293.0
WLSH2_k127_3402103_6 sugar phosphatases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001534 236.0
WLSH2_k127_3402103_7 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000008121 230.0
WLSH2_k127_3402103_8 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000001064 206.0
WLSH2_k127_3402103_9 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000000000000000001369 196.0
WLSH2_k127_3434874_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 2.405e-293 921.0
WLSH2_k127_3434874_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.845e-194 614.0
WLSH2_k127_3434874_10 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 415.0
WLSH2_k127_3434874_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 353.0
WLSH2_k127_3434874_12 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 301.0
WLSH2_k127_3434874_13 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006314 283.0
WLSH2_k127_3434874_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 252.0
WLSH2_k127_3434874_15 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000003001 206.0
WLSH2_k127_3434874_16 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.000000000000000000000000000000000000000000000000000000001834 221.0
WLSH2_k127_3434874_17 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01450,K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.31,3.5.1.88 0.0000000000000000000000000000000000000000000000000000003458 198.0
WLSH2_k127_3434874_18 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000004435 191.0
WLSH2_k127_3434874_19 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein - - - 0.000000000000000000000000000000000000000000000005594 192.0
WLSH2_k127_3434874_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 613.0
WLSH2_k127_3434874_20 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000004589 168.0
WLSH2_k127_3434874_21 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000001164 158.0
WLSH2_k127_3434874_22 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.000000000000000000000000000004063 126.0
WLSH2_k127_3434874_23 transcriptional regulator - - - 0.000000000000000000000003938 106.0
WLSH2_k127_3434874_24 Transmembrane protein 43 - - - 0.0000000000000000006162 103.0
WLSH2_k127_3434874_25 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.0000000000000004323 87.0
WLSH2_k127_3434874_26 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000001929 71.0
WLSH2_k127_3434874_27 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000003705 60.0
WLSH2_k127_3434874_28 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00003266 51.0
WLSH2_k127_3434874_3 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 571.0
WLSH2_k127_3434874_4 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 502.0
WLSH2_k127_3434874_5 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 492.0
WLSH2_k127_3434874_6 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 471.0
WLSH2_k127_3434874_7 reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 469.0
WLSH2_k127_3434874_8 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 462.0
WLSH2_k127_3434874_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 431.0
WLSH2_k127_3484486_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 525.0
WLSH2_k127_3484486_1 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 300.0
WLSH2_k127_3484486_2 Removal of H(2)O(2), oxidation of toxic reductants, biosynthesis and degradation of lignin, suberization, auxin catabolism, response to environmental stresses such as wounding, pathogen attack and oxidative stress. These functions might be dependent on each isozyme isoform in each plant tissue - - - 0.00000000000000000000000000000000006499 151.0
WLSH2_k127_3484486_3 Elongation factor - - - 0.000000000000000000000000000001694 126.0
WLSH2_k127_3484486_4 FAD linked oxidase domain protein K05797 - 1.17.99.1 0.0000000000000000000000009893 107.0
WLSH2_k127_3484486_5 SlyX K03745 - - 0.0006973 45.0
WLSH2_k127_3758724_0 SNF2 family N-terminal domain - - - 3.783e-267 860.0
WLSH2_k127_3758724_1 DnaJ C terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
WLSH2_k127_3758724_10 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000005314 151.0
WLSH2_k127_3758724_11 Ferritin-like domain K04047 - - 0.0000000000000000000000000000000000008131 144.0
WLSH2_k127_3758724_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000001711 103.0
WLSH2_k127_3758724_13 MerR HTH family regulatory protein K18997 - - 0.000000000000004719 79.0
WLSH2_k127_3758724_14 - - - - 0.00000000001335 71.0
WLSH2_k127_3758724_15 - - - - 0.0000000002221 66.0
WLSH2_k127_3758724_16 Protein required for attachment to host cells - - - 0.00000001169 62.0
WLSH2_k127_3758724_17 Domain of unknown function (DUF4143) K07133 - - 0.000003179 53.0
WLSH2_k127_3758724_18 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03321 - - 0.0002103 45.0
WLSH2_k127_3758724_2 Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003397 253.0
WLSH2_k127_3758724_3 Peptidoglycan-binding domain 1 protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000193 255.0
WLSH2_k127_3758724_4 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005621 255.0
WLSH2_k127_3758724_5 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.0000000000000000000000000000000000000000000000000000000000002889 216.0
WLSH2_k127_3758724_6 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000006313 195.0
WLSH2_k127_3758724_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000003658 190.0
WLSH2_k127_3758724_8 - - - - 0.00000000000000000000000000000000000000000005566 168.0
WLSH2_k127_3758724_9 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000000000000000000183 163.0
WLSH2_k127_3818981_0 Belongs to the ClpA ClpB family K03694 - - 4.731e-296 928.0
WLSH2_k127_3818981_1 Type IV secretion system protein VirD4 K03205 - - 8.609e-257 804.0
WLSH2_k127_3818981_10 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 351.0
WLSH2_k127_3818981_11 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 353.0
WLSH2_k127_3818981_12 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 345.0
WLSH2_k127_3818981_13 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 341.0
WLSH2_k127_3818981_14 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 339.0
WLSH2_k127_3818981_15 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 312.0
WLSH2_k127_3818981_16 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000009982 261.0
WLSH2_k127_3818981_17 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000006854 242.0
WLSH2_k127_3818981_18 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000005227 222.0
WLSH2_k127_3818981_19 type IV secretory pathway, VirB10 components K03195 - - 0.000000000000000000000000000000000000000000000000000000000002699 227.0
WLSH2_k127_3818981_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.562e-246 780.0
WLSH2_k127_3818981_20 Type IV secretion system protein VirB9 K03204 - - 0.00000000000000000000000000000000000000000000000000000000004207 214.0
WLSH2_k127_3818981_21 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000005907 205.0
WLSH2_k127_3818981_22 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000008968 206.0
WLSH2_k127_3818981_23 - - - - 0.00000000000000000000000000000000000000000002325 163.0
WLSH2_k127_3818981_24 type IV secretion K03203 - - 0.00000000000000000000000000000000000000000002668 170.0
WLSH2_k127_3818981_25 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000008794 165.0
WLSH2_k127_3818981_26 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000008001 145.0
WLSH2_k127_3818981_27 Tetratricopeptide repeats - - - 0.000000000000000000000000000000007533 138.0
WLSH2_k127_3818981_28 Glycoprotease family K01409,K14742 - 2.3.1.234 0.0000000000000000000000000000001234 134.0
WLSH2_k127_3818981_29 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000000000000000004223 120.0
WLSH2_k127_3818981_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.441e-221 709.0
WLSH2_k127_3818981_30 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000007777 116.0
WLSH2_k127_3818981_31 Dehydrogenase - - - 0.0000000000000000000000006337 121.0
WLSH2_k127_3818981_32 - - - - 0.00000000000000000000000506 115.0
WLSH2_k127_3818981_33 - - - - 0.00000000000000000000003333 99.0
WLSH2_k127_3818981_34 - - - - 0.000000000000000000001236 106.0
WLSH2_k127_3818981_35 - - - - 0.0000000000000001413 79.0
WLSH2_k127_3818981_36 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000006797 76.0
WLSH2_k127_3818981_37 - - - - 0.0000000000001063 71.0
WLSH2_k127_3818981_38 - - - - 0.000000000007062 65.0
WLSH2_k127_3818981_39 RDD family - - - 0.00000000001291 73.0
WLSH2_k127_3818981_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.101e-195 623.0
WLSH2_k127_3818981_42 unfolded protein binding K06142 - - 0.00008374 51.0
WLSH2_k127_3818981_5 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 532.0
WLSH2_k127_3818981_6 Type II/IV secretion system protein K03196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 477.0
WLSH2_k127_3818981_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 453.0
WLSH2_k127_3818981_8 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 377.0
WLSH2_k127_3818981_9 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 366.0
WLSH2_k127_4142361_0 Ketoacyl-synthetase C-terminal extension K21783 - - 0.0 2389.0
WLSH2_k127_4142361_1 Ketoacyl-synthetase C-terminal extension K04786,K13613 - - 0.0 1056.0
WLSH2_k127_4142361_10 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000152 184.0
WLSH2_k127_4142361_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000001709 184.0
WLSH2_k127_4142361_12 COG1538 Outer membrane protein K12340 - - 0.000000000000000000000000000000008329 144.0
WLSH2_k127_4142361_13 protein localization to T-tubule K10380,K15503,K21440 - - 0.000000000000000000002533 105.0
WLSH2_k127_4142361_14 nUDIX hydrolase - - - 0.0000000000000005422 89.0
WLSH2_k127_4142361_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000009551 72.0
WLSH2_k127_4142361_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 3.877e-226 713.0
WLSH2_k127_4142361_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.528e-208 660.0
WLSH2_k127_4142361_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008481 548.0
WLSH2_k127_4142361_5 Biotin-lipoyl like K01993,K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 419.0
WLSH2_k127_4142361_6 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 373.0
WLSH2_k127_4142361_7 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 354.0
WLSH2_k127_4142361_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000002835 237.0
WLSH2_k127_4142361_9 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000000000000001936 200.0
WLSH2_k127_4462011_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1263.0
WLSH2_k127_4462011_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1022.0
WLSH2_k127_4462011_10 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 556.0
WLSH2_k127_4462011_11 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 546.0
WLSH2_k127_4462011_12 response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 488.0
WLSH2_k127_4462011_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 482.0
WLSH2_k127_4462011_14 RNA polymerases D K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 477.0
WLSH2_k127_4462011_15 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 428.0
WLSH2_k127_4462011_16 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 436.0
WLSH2_k127_4462011_17 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 417.0
WLSH2_k127_4462011_18 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 418.0
WLSH2_k127_4462011_19 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 404.0
WLSH2_k127_4462011_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 9.927e-299 925.0
WLSH2_k127_4462011_20 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
WLSH2_k127_4462011_21 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 342.0
WLSH2_k127_4462011_22 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 329.0
WLSH2_k127_4462011_23 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 329.0
WLSH2_k127_4462011_24 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 329.0
WLSH2_k127_4462011_25 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 298.0
WLSH2_k127_4462011_26 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 298.0
WLSH2_k127_4462011_27 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 305.0
WLSH2_k127_4462011_28 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005385,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006829,GO:0006873,GO:0006875,GO:0006876,GO:0006882,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015086,GO:0015093,GO:0015291,GO:0015318,GO:0015341,GO:0015562,GO:0015684,GO:0015691,GO:0016020,GO:0019725,GO:0022804,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0030003,GO:0034220,GO:0034755,GO:0042592,GO:0042802,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055069,GO:0055073,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070574,GO:0070838,GO:0071577,GO:0071944,GO:0072503,GO:0072507,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:1903874 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 293.0
WLSH2_k127_4462011_29 PFAM Carbohydrate-selective porin OprB K07267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003465 286.0
WLSH2_k127_4462011_3 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 1.653e-295 925.0
WLSH2_k127_4462011_30 Ribonuclease, BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003943 271.0
WLSH2_k127_4462011_31 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003113 257.0
WLSH2_k127_4462011_32 response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001123 258.0
WLSH2_k127_4462011_33 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001761 250.0
WLSH2_k127_4462011_34 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000003006 214.0
WLSH2_k127_4462011_35 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000001507 208.0
WLSH2_k127_4462011_36 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000001342 203.0
WLSH2_k127_4462011_37 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000008235 209.0
WLSH2_k127_4462011_38 Sigma 54 modulation/S30EA ribosomal protein C terminus - - - 0.000000000000000000000000000000000000000000000000000003655 197.0
WLSH2_k127_4462011_39 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000001576 203.0
WLSH2_k127_4462011_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.203e-275 880.0
WLSH2_k127_4462011_40 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000001761 184.0
WLSH2_k127_4462011_41 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000001822 175.0
WLSH2_k127_4462011_42 COQ9 K18587 - - 0.000000000000000000000000000000000000000000001011 172.0
WLSH2_k127_4462011_43 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000133 166.0
WLSH2_k127_4462011_44 17 kDa surface antigen - - - 0.000000000000000000000000000000000000000002087 161.0
WLSH2_k127_4462011_45 COG0784 FOG CheY-like receiver K11443 - - 0.00000000000000000000000000000000000000005607 154.0
WLSH2_k127_4462011_46 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000000000000000000000000000000000005151 150.0
WLSH2_k127_4462011_47 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000005569 136.0
WLSH2_k127_4462011_48 PFAM Plasmid stabilisation system K06218 - - 0.00000000000000000000000000000000677 129.0
WLSH2_k127_4462011_49 Mortierella verticillata NRRL 6337 - - - 0.00000000000000000000000000000008351 143.0
WLSH2_k127_4462011_5 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.689e-252 788.0
WLSH2_k127_4462011_50 Outer membrane lipoprotein - - - 0.000000000000000000000000001496 119.0
WLSH2_k127_4462011_51 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.00000000000000000000000004114 119.0
WLSH2_k127_4462011_52 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000001822 108.0
WLSH2_k127_4462011_53 Antitoxin component of a toxin-antitoxin (TA) module K18923 - - 0.00000000000000000002905 93.0
WLSH2_k127_4462011_54 Ribosomal protein L30p/L7e K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000008496 91.0
WLSH2_k127_4462011_55 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000000009686 92.0
WLSH2_k127_4462011_56 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000001831 88.0
WLSH2_k127_4462011_57 Prokaryotic N-terminal methylation motif - - - 0.0000000000000001088 88.0
WLSH2_k127_4462011_58 beta-lactamase activity K07126 - - 0.000000000000000276 83.0
WLSH2_k127_4462011_59 Domain of unknown function (DUF4340) - - - 0.00000000000001735 85.0
WLSH2_k127_4462011_6 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.922e-203 641.0
WLSH2_k127_4462011_60 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000006027 71.0
WLSH2_k127_4462011_61 Membrane Localization Domain - - - 0.00000000001047 76.0
WLSH2_k127_4462011_62 - - - - 0.000000001183 64.0
WLSH2_k127_4462011_63 Addiction module - - - 0.000000009913 61.0
WLSH2_k127_4462011_64 - - - - 0.0000001449 55.0
WLSH2_k127_4462011_65 Histidine kinase K07716 - 2.7.13.3 0.000001609 60.0
WLSH2_k127_4462011_66 retrograde transport, endosome to plasma membrane K15502 - - 0.000006756 54.0
WLSH2_k127_4462011_68 - - - - 0.00009637 49.0
WLSH2_k127_4462011_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 9.942e-194 618.0
WLSH2_k127_4462011_8 Ribonucleotide reductase, small chain K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 565.0
WLSH2_k127_4462011_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 562.0
WLSH2_k127_4809271_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01537 - 3.6.3.8 9.409e-271 859.0
WLSH2_k127_4809271_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 606.0
WLSH2_k127_4809271_2 thymidine phosphorylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 593.0
WLSH2_k127_4809271_3 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 290.0
WLSH2_k127_4809271_4 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.00000000000000000000000000000000000000001055 157.0
WLSH2_k127_4811090_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1124.0
WLSH2_k127_4811090_1 DNA Topoisomerase IV K02621 - - 0.0 1015.0
WLSH2_k127_4811090_10 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 306.0
WLSH2_k127_4811090_11 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 299.0
WLSH2_k127_4811090_12 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 294.0
WLSH2_k127_4811090_13 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002599 282.0
WLSH2_k127_4811090_14 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 260.0
WLSH2_k127_4811090_15 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000005122 230.0
WLSH2_k127_4811090_16 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000001756 214.0
WLSH2_k127_4811090_17 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000006693 184.0
WLSH2_k127_4811090_18 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000002211 177.0
WLSH2_k127_4811090_19 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000001384 177.0
WLSH2_k127_4811090_2 Histidine kinase K03407 - 2.7.13.3 8.005e-230 742.0
WLSH2_k127_4811090_20 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000002869 171.0
WLSH2_k127_4811090_21 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000001902 161.0
WLSH2_k127_4811090_22 COG0835 Chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000000000003394 138.0
WLSH2_k127_4811090_23 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000002165 143.0
WLSH2_k127_4811090_24 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000002683 123.0
WLSH2_k127_4811090_25 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000005497 119.0
WLSH2_k127_4811090_26 - - - - 0.0000000000000000000000006141 113.0
WLSH2_k127_4811090_27 Histidine phosphotransferase C-terminal domain K13588 - - 0.000000000000000000000004918 109.0
WLSH2_k127_4811090_28 ATP hydrolysis coupled proton transport K02128,K03880 GO:0000276,GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005753,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006839,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009651,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016310,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0019866,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031090,GO:0031224,GO:0031966,GO:0031967,GO:0031975,GO:0032991,GO:0033177,GO:0033554,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042776,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046907,GO:0046933,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055085,GO:0055086,GO:0071214,GO:0071470,GO:0071472,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098798,GO:0098800,GO:0099131,GO:0099132,GO:0104004,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600,GO:1990542 1.6.5.3 0.000000000000000000001109 98.0
WLSH2_k127_4811090_29 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000009749 98.0
WLSH2_k127_4811090_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 538.0
WLSH2_k127_4811090_31 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000001532 59.0
WLSH2_k127_4811090_32 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000005093 59.0
WLSH2_k127_4811090_33 - K20326 - - 0.0000008097 60.0
WLSH2_k127_4811090_4 Glycosyl transferase family group 2 K20327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 483.0
WLSH2_k127_4811090_5 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 467.0
WLSH2_k127_4811090_6 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 426.0
WLSH2_k127_4811090_7 stress, protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 382.0
WLSH2_k127_4811090_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 339.0
WLSH2_k127_4811090_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 302.0
WLSH2_k127_4873180_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 3.141e-255 798.0
WLSH2_k127_4873180_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.668e-223 702.0
WLSH2_k127_4873180_10 shape-determining protein K03571 - - 0.00000000000037 76.0
WLSH2_k127_4873180_2 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 599.0
WLSH2_k127_4873180_3 Rod shape-determining protein (MreB) K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 539.0
WLSH2_k127_4873180_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 473.0
WLSH2_k127_4873180_5 Belongs to the SEDS family. MrdB RodA subfamily K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 419.0
WLSH2_k127_4873180_6 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000008182 191.0
WLSH2_k127_4873180_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001058 177.0
WLSH2_k127_4873180_8 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000003523 171.0
WLSH2_k127_4873180_9 Siderophore biosynthesis protein domain K00663 - 2.3.1.82 0.000000000000000000000008487 108.0
WLSH2_k127_4968286_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 527.0
WLSH2_k127_4968286_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 459.0
WLSH2_k127_4968286_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 441.0
WLSH2_k127_4968286_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 425.0
WLSH2_k127_4968286_4 Restriction endonuclease K07448 - - 0.00000000000000000000002502 112.0
WLSH2_k127_4968286_5 sequence-specific DNA binding - - - 0.000003051 55.0
WLSH2_k127_4984150_0 Belongs to the 'phage' integrase family K03733,K04763 - - 0.00000000000000000000000000000000000372 149.0
WLSH2_k127_4984150_1 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000006845 117.0
WLSH2_k127_5005135_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 496.0
WLSH2_k127_5005135_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 445.0
WLSH2_k127_5005135_2 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002665 284.0
WLSH2_k127_5005135_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000001135 219.0
WLSH2_k127_5005135_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
WLSH2_k127_5005135_5 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000007547 213.0
WLSH2_k127_5005135_6 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000001399 183.0
WLSH2_k127_5005135_7 COG1607 Acyl-CoA hydrolase K10806 - - 0.0000000000000000000000000000000000000000000007755 168.0
WLSH2_k127_5031915_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.218e-201 634.0
WLSH2_k127_5031915_1 phosphomannomutase K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 520.0
WLSH2_k127_5031915_10 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000000000000000000000000000000000000007059 215.0
WLSH2_k127_5031915_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001281 213.0
WLSH2_k127_5031915_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000009841 207.0
WLSH2_k127_5031915_13 Membrane K08988 - - 0.00000000000000000000000000000000002003 143.0
WLSH2_k127_5031915_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000002836 112.0
WLSH2_k127_5031915_15 - - - - 0.000000000000005589 81.0
WLSH2_k127_5031915_16 Domain of unknown function (DUF4115) K15539 - - 0.000000003923 66.0
WLSH2_k127_5031915_17 Sel1 domain protein repeat-containing protein K07126 - - 0.000000005276 67.0
WLSH2_k127_5031915_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 449.0
WLSH2_k127_5031915_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 415.0
WLSH2_k127_5031915_4 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
WLSH2_k127_5031915_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 312.0
WLSH2_k127_5031915_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
WLSH2_k127_5031915_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
WLSH2_k127_5031915_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001582 261.0
WLSH2_k127_5031915_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000177 259.0
WLSH2_k127_5459314_0 DNA polymerase K02337 - 2.7.7.7 0.0 1252.0
WLSH2_k127_5459314_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1020.0
WLSH2_k127_5459314_10 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 414.0
WLSH2_k127_5459314_11 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 392.0
WLSH2_k127_5459314_12 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 394.0
WLSH2_k127_5459314_13 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 378.0
WLSH2_k127_5459314_14 Fic/DOC family K04095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 342.0
WLSH2_k127_5459314_15 Cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 342.0
WLSH2_k127_5459314_16 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 292.0
WLSH2_k127_5459314_17 Domain of Unknown Function (DUF350) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000398 288.0
WLSH2_k127_5459314_18 molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006384 267.0
WLSH2_k127_5459314_19 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0015031,GO:0015399,GO:0015405,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022804,GO:0022857,GO:0031224,GO:0032991,GO:0033036,GO:0042157,GO:0042160,GO:0042623,GO:0042626,GO:0042886,GO:0042953,GO:0043170,GO:0043190,GO:0043492,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901564,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003199 264.0
WLSH2_k127_5459314_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 5.633e-268 855.0
WLSH2_k127_5459314_20 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000018 253.0
WLSH2_k127_5459314_21 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000004179 253.0
WLSH2_k127_5459314_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000042 250.0
WLSH2_k127_5459314_23 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
WLSH2_k127_5459314_24 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000009288 239.0
WLSH2_k127_5459314_25 to M. xanthus CarD K07736 - - 0.00000000000000000000000000000000000000000000000000000000005797 211.0
WLSH2_k127_5459314_26 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000002473 186.0
WLSH2_k127_5459314_27 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000002212 175.0
WLSH2_k127_5459314_28 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000002122 155.0
WLSH2_k127_5459314_29 HIRAN domain - - - 0.000000000000000000000000000000000000348 149.0
WLSH2_k127_5459314_3 to multidrug resistance ABC transporter ATP-binding protein K06147 - - 3.084e-209 666.0
WLSH2_k127_5459314_30 - - - - 0.0000000000000000000001988 104.0
WLSH2_k127_5459314_31 Thioesterase domain K02170 - 3.1.1.85 0.00000000001565 73.0
WLSH2_k127_5459314_32 metal cluster binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000257 69.0
WLSH2_k127_5459314_34 Phasin protein - - - 0.000008735 54.0
WLSH2_k127_5459314_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.89e-205 643.0
WLSH2_k127_5459314_5 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 3.061e-197 623.0
WLSH2_k127_5459314_6 ATPase with chaperone activity K07391 - - 2.045e-194 618.0
WLSH2_k127_5459314_7 Aminotransferase class-III K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 480.0
WLSH2_k127_5459314_8 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 472.0
WLSH2_k127_5459314_9 lipoprotein releasing system, transmembrane protein, LolC E family' K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 458.0
WLSH2_k127_5462380_0 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 6.705e-288 898.0
WLSH2_k127_5462380_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 6.137e-266 832.0
WLSH2_k127_5462380_10 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 462.0
WLSH2_k127_5462380_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 452.0
WLSH2_k127_5462380_12 Phage portal protein, HK97 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 451.0
WLSH2_k127_5462380_13 Phage major capsid protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 439.0
WLSH2_k127_5462380_14 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 422.0
WLSH2_k127_5462380_15 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 417.0
WLSH2_k127_5462380_16 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 351.0
WLSH2_k127_5462380_17 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 332.0
WLSH2_k127_5462380_18 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331,K03940 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 320.0
WLSH2_k127_5462380_19 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 302.0
WLSH2_k127_5462380_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 5.65e-226 705.0
WLSH2_k127_5462380_20 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 312.0
WLSH2_k127_5462380_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 286.0
WLSH2_k127_5462380_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity) K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002525 263.0
WLSH2_k127_5462380_23 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002916 269.0
WLSH2_k127_5462380_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000006766 245.0
WLSH2_k127_5462380_25 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000003519 231.0
WLSH2_k127_5462380_26 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001384 220.0
WLSH2_k127_5462380_27 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000006209 208.0
WLSH2_k127_5462380_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000003949 198.0
WLSH2_k127_5462380_29 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000001937 180.0
WLSH2_k127_5462380_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.164e-208 659.0
WLSH2_k127_5462380_30 Caudovirus prohead serine protease K06904 - - 0.00000000000000000000000000000000000000000002008 168.0
WLSH2_k127_5462380_31 Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000003244 159.0
WLSH2_k127_5462380_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000006916 153.0
WLSH2_k127_5462380_33 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000004297 163.0
WLSH2_k127_5462380_34 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.000000000000000000000000000000001064 143.0
WLSH2_k127_5462380_35 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.0000000000000000000000000000000083 136.0
WLSH2_k127_5462380_36 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000004195 129.0
WLSH2_k127_5462380_37 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000001372 110.0
WLSH2_k127_5462380_38 OmpA family K03286 - - 0.0000000000000000000000002487 118.0
WLSH2_k127_5462380_39 Phage gp6-like head-tail connector protein - - - 0.000000000000000000000003588 111.0
WLSH2_k127_5462380_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 8.482e-207 647.0
WLSH2_k127_5462380_40 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000001118 97.0
WLSH2_k127_5462380_41 - - - - 0.000000000000000000001181 99.0
WLSH2_k127_5462380_42 transcriptional regulators K03892 - - 0.00000000000000000001275 94.0
WLSH2_k127_5462380_43 tail protein - - - 0.00000000000000000001416 96.0
WLSH2_k127_5462380_44 Met-10+ like-protein - - - 0.00000000000000000005035 101.0
WLSH2_k127_5462380_45 Phage head-tail joining protein - - - 0.0000000000000000399 85.0
WLSH2_k127_5462380_46 Tetratricopeptide repeat-like domain - - - 0.000000000000002338 85.0
WLSH2_k127_5462380_47 Prokaryotic N-terminal methylation motif - - - 0.00000000000003018 82.0
WLSH2_k127_5462380_48 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000004162 69.0
WLSH2_k127_5462380_49 Protein of unknown function (DUF1465) K13592 - - 0.0000000002801 66.0
WLSH2_k127_5462380_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 2.221e-206 651.0
WLSH2_k127_5462380_50 - - - - 0.00001349 55.0
WLSH2_k127_5462380_51 Protein of unknown function (DUF3168) - - - 0.00002077 52.0
WLSH2_k127_5462380_6 metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 530.0
WLSH2_k127_5462380_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 512.0
WLSH2_k127_5462380_8 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 513.0
WLSH2_k127_5462380_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 467.0
WLSH2_k127_5464582_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1295.0
WLSH2_k127_5464582_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.204e-231 735.0
WLSH2_k127_5464582_10 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 340.0
WLSH2_k127_5464582_11 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 313.0
WLSH2_k127_5464582_12 COG0616 Periplasmic serine proteases (ClpP class) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 293.0
WLSH2_k127_5464582_13 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004407 247.0
WLSH2_k127_5464582_14 Phage lysozyme K01185 - 3.2.1.17 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
WLSH2_k127_5464582_15 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.000000000000000000000000000000000000000000000000000000006527 209.0
WLSH2_k127_5464582_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000001353 183.0
WLSH2_k127_5464582_17 - - - - 0.000000000000000000000000000000000000000000000000355 184.0
WLSH2_k127_5464582_18 - - - - 0.0000000000000000000000000000000000000000000000006559 181.0
WLSH2_k127_5464582_19 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000005847 173.0
WLSH2_k127_5464582_2 ABC-type oligopeptide transport system, periplasmic component K02035,K13893 - - 2.239e-214 685.0
WLSH2_k127_5464582_20 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000009225 162.0
WLSH2_k127_5464582_21 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000289 168.0
WLSH2_k127_5464582_22 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.00000000000000000000000000000000000000005486 156.0
WLSH2_k127_5464582_23 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000001851 150.0
WLSH2_k127_5464582_24 COG3474 Cytochrome c2 K08738 - - 0.000000000000000000000000000000000000405 145.0
WLSH2_k127_5464582_25 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000002521 141.0
WLSH2_k127_5464582_26 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000004605 137.0
WLSH2_k127_5464582_27 EamA-like transporter family K15270 - - 0.000000000000000000000000000007115 132.0
WLSH2_k127_5464582_28 Mechanosensitive ion channel - - - 0.00000000000000000000000000004254 123.0
WLSH2_k127_5464582_29 Usg-like family - - - 0.0000000000000000000000000006621 115.0
WLSH2_k127_5464582_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 7.007e-200 632.0
WLSH2_k127_5464582_30 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000001715 121.0
WLSH2_k127_5464582_31 Protein of unknown function (DUF3800) - - - 0.00000000000000000000003746 106.0
WLSH2_k127_5464582_32 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.00000000000000000003803 99.0
WLSH2_k127_5464582_33 Ankyrin repeat - - - 0.0000000002371 73.0
WLSH2_k127_5464582_34 Glycosyl transferase, family 2 - - - 0.0000005163 55.0
WLSH2_k127_5464582_35 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0001992 53.0
WLSH2_k127_5464582_4 Aminotransferase class-III - - - 3.035e-197 624.0
WLSH2_k127_5464582_5 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 480.0
WLSH2_k127_5464582_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 476.0
WLSH2_k127_5464582_7 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 460.0
WLSH2_k127_5464582_8 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 445.0
WLSH2_k127_5464582_9 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0000287,GO:0003674,GO:0003824,GO:0004474,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009436,GO:0009987,GO:0015980,GO:0016054,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046185,GO:0046395,GO:0046487,GO:0046872,GO:0046912,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:1901575 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 402.0
WLSH2_k127_56032_0 type IV secretion system protein K03199 - - 0.0 1127.0
WLSH2_k127_56032_1 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1111.0
WLSH2_k127_56032_10 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 589.0
WLSH2_k127_56032_11 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006589 554.0
WLSH2_k127_56032_12 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 551.0
WLSH2_k127_56032_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 549.0
WLSH2_k127_56032_14 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 539.0
WLSH2_k127_56032_15 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 506.0
WLSH2_k127_56032_16 CoA binding domain K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 500.0
WLSH2_k127_56032_17 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 504.0
WLSH2_k127_56032_18 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 486.0
WLSH2_k127_56032_19 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 458.0
WLSH2_k127_56032_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.867e-257 809.0
WLSH2_k127_56032_20 Domain of unknown function (DUF3333) K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 445.0
WLSH2_k127_56032_21 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 425.0
WLSH2_k127_56032_22 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 413.0
WLSH2_k127_56032_23 Ferrochelatase K01772 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 407.0
WLSH2_k127_56032_24 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 404.0
WLSH2_k127_56032_25 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 394.0
WLSH2_k127_56032_26 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 393.0
WLSH2_k127_56032_27 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 383.0
WLSH2_k127_56032_28 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 368.0
WLSH2_k127_56032_29 membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 370.0
WLSH2_k127_56032_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.213e-255 792.0
WLSH2_k127_56032_30 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 376.0
WLSH2_k127_56032_31 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 351.0
WLSH2_k127_56032_32 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 338.0
WLSH2_k127_56032_33 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 336.0
WLSH2_k127_56032_34 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
WLSH2_k127_56032_35 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 327.0
WLSH2_k127_56032_36 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 323.0
WLSH2_k127_56032_37 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 314.0
WLSH2_k127_56032_38 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 312.0
WLSH2_k127_56032_39 Pfam:DUF328 K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 297.0
WLSH2_k127_56032_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.864e-253 788.0
WLSH2_k127_56032_40 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 299.0
WLSH2_k127_56032_41 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 294.0
WLSH2_k127_56032_42 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 302.0
WLSH2_k127_56032_43 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004134 283.0
WLSH2_k127_56032_44 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006061 274.0
WLSH2_k127_56032_45 Transposase K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001941 276.0
WLSH2_k127_56032_46 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
WLSH2_k127_56032_47 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001182 259.0
WLSH2_k127_56032_48 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004433 257.0
WLSH2_k127_56032_49 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000001444 211.0
WLSH2_k127_56032_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.873e-253 798.0
WLSH2_k127_56032_50 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
WLSH2_k127_56032_51 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000001665 204.0
WLSH2_k127_56032_52 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000299 208.0
WLSH2_k127_56032_53 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000006119 187.0
WLSH2_k127_56032_54 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000243 195.0
WLSH2_k127_56032_55 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000006591 184.0
WLSH2_k127_56032_56 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000001843 177.0
WLSH2_k127_56032_57 Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000001659 169.0
WLSH2_k127_56032_58 Acid phosphatase homologues K12978 - - 0.00000000000000000000000000000000000000000006277 168.0
WLSH2_k127_56032_59 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000349 162.0
WLSH2_k127_56032_6 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.225e-227 726.0
WLSH2_k127_56032_60 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000001202 168.0
WLSH2_k127_56032_61 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000001622 164.0
WLSH2_k127_56032_62 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000009536 158.0
WLSH2_k127_56032_63 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.0000000000000000000000000000000000000001261 153.0
WLSH2_k127_56032_64 Flagellar basal body rod FlgEFG protein C-terminal K02388 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.000000000000000000000000000000000000000919 153.0
WLSH2_k127_56032_65 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000001895 145.0
WLSH2_k127_56032_66 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000002445 141.0
WLSH2_k127_56032_67 protein conserved in bacteria - - - 0.000000000000000000000000000000003182 135.0
WLSH2_k127_56032_68 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000002585 126.0
WLSH2_k127_56032_69 TfoX N-terminal domain - - - 0.0000000000000000000000000000009116 124.0
WLSH2_k127_56032_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.026e-200 636.0
WLSH2_k127_56032_70 ZU5 domain K10380,K21440 GO:0000902,GO:0000904,GO:0001508,GO:0002027,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003205,GO:0003230,GO:0003279,GO:0003283,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0005911,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006888,GO:0006928,GO:0006935,GO:0006936,GO:0006937,GO:0006941,GO:0006942,GO:0007009,GO:0007154,GO:0007165,GO:0007267,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007507,GO:0008015,GO:0008016,GO:0008092,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009893,GO:0009987,GO:0010171,GO:0010256,GO:0010468,GO:0010522,GO:0010604,GO:0010628,GO:0010646,GO:0010880,GO:0010881,GO:0010882,GO:0010959,GO:0014069,GO:0014704,GO:0015459,GO:0016020,GO:0016021,GO:0016043,GO:0016192,GO:0016247,GO:0016323,GO:0016328,GO:0019222,GO:0019722,GO:0019725,GO:0019899,GO:0019900,GO:0019901,GO:0019932,GO:0022008,GO:0022898,GO:0023051,GO:0023052,GO:0030001,GO:0030003,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030030,GO:0030048,GO:0030054,GO:0030154,GO:0030182,GO:0030315,GO:0030507,GO:0030674,GO:0031175,GO:0031224,GO:0031226,GO:0031430,GO:0031647,GO:0031672,GO:0031674,GO:0032279,GO:0032409,GO:0032411,GO:0032412,GO:0032414,GO:0032501,GO:0032502,GO:0032879,GO:0032970,GO:0032989,GO:0032990,GO:0033036,GO:0033292,GO:0033365,GO:0033563,GO:0034394,GO:0034613,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0035556,GO:0035637,GO:0036309,GO:0036371,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042692,GO:0043034,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043266,GO:0043268,GO:0043269,GO:0043270,GO:0043292,GO:0044057,GO:0044093,GO:0044291,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044464,GO:0045202,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048522,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050821,GO:0050839,GO:0050896,GO:0051049,GO:0051050,GO:0051094,GO:0051117,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051270,GO:0051279,GO:0051282,GO:0051641,GO:0051649,GO:0051716,GO:0051899,GO:0051924,GO:0051928,GO:0055001,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055117,GO:0060047,GO:0060048,GO:0060090,GO:0060255,GO:0060306,GO:0060307,GO:0060341,GO:0061024,GO:0061061,GO:0061337,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070252,GO:0070296,GO:0070727,GO:0070838,GO:0070972,GO:0071840,GO:0071944,GO:0072359,GO:0072503,GO:0072507,GO:0072511,GO:0072657,GO:0072659,GO:0086001,GO:0086002,GO:0086003,GO:0086004,GO:0086005,GO:0086010,GO:0086012,GO:0086014,GO:0086015,GO:0086018,GO:0086019,GO:0086026,GO:0086036,GO:0086046,GO:0086065,GO:0086066,GO:0086070,GO:0086091,GO:0090257,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098772,GO:0098794,GO:0098900,GO:0098901,GO:0098904,GO:0098907,GO:0098910,GO:0098984,GO:0099080,GO:0099081,GO:0099106,GO:0099512,GO:0099572,GO:0099623,GO:0120036,GO:0120039,GO:1901016,GO:1901018,GO:1901019,GO:1901021,GO:1901379,GO:1901381,GO:1903115,GO:1903169,GO:1903522,GO:1903779,GO:1904062,GO:1904064,GO:1904427,GO:1990778,GO:2001257,GO:2001259 - 0.0000000000000000000000000000831 132.0
WLSH2_k127_56032_71 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000009502 116.0
WLSH2_k127_56032_72 Acetyltransferase - - - 0.000000000000000000000000002578 115.0
WLSH2_k127_56032_73 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000008551 118.0
WLSH2_k127_56032_74 Acetyltransferase (GNAT) domain K03826 - - 0.00000000000000000000000008977 111.0
WLSH2_k127_56032_75 type IV secretion system K03201 - - 0.0000000000000000000000008518 122.0
WLSH2_k127_56032_76 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000000000000004521 111.0
WLSH2_k127_56032_77 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000004584 106.0
WLSH2_k127_56032_78 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000005083 105.0
WLSH2_k127_56032_79 regulator - - - 0.000000000000000000000006579 105.0
WLSH2_k127_56032_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 608.0
WLSH2_k127_56032_80 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000006567 100.0
WLSH2_k127_56032_81 Role in flagellar biosynthesis K02420 - - 0.00000000000000000001614 93.0
WLSH2_k127_56032_82 Type IV secretory pathway, VirB3 components K03198 - - 0.000000000000000000095 93.0
WLSH2_k127_56032_83 DoxX K15977 - - 0.00000000000000002242 89.0
WLSH2_k127_56032_84 - - - - 0.0000000000000009243 79.0
WLSH2_k127_56032_85 domain protein - - - 0.00000000000001141 91.0
WLSH2_k127_56032_86 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000001219 72.0
WLSH2_k127_56032_87 COG3704 Type IV secretory pathway, VirB6 components K03201 - - 0.0000000000002119 84.0
WLSH2_k127_56032_88 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.0000000000003066 86.0
WLSH2_k127_56032_89 - - - - 0.000000000001157 74.0
WLSH2_k127_56032_9 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 599.0
WLSH2_k127_56032_90 Type IV secretory pathway, VirB6 components K03201 - - 0.000000000008593 80.0
WLSH2_k127_56032_91 SpoVT / AbrB like domain - - - 0.00000000009534 65.0
WLSH2_k127_56032_92 Flagellar hook-basal body K02408 - - 0.0000000001507 66.0
WLSH2_k127_56032_96 Glucose / Sorbosone dehydrogenase K04753 - - 0.0002631 56.0
WLSH2_k127_56032_97 Major Facilitator Superfamily - - - 0.0007322 46.0
WLSH2_k127_5699450_0 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 428.0
WLSH2_k127_5699450_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 387.0
WLSH2_k127_5699450_10 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000007061 132.0
WLSH2_k127_5699450_11 general secretion pathway protein - - - 0.000000000000000000000000008542 124.0
WLSH2_k127_5699450_12 general secretion pathway protein - - - 0.000000000000000000000001631 114.0
WLSH2_k127_5699450_2 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 381.0
WLSH2_k127_5699450_3 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 368.0
WLSH2_k127_5699450_4 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 296.0
WLSH2_k127_5699450_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 293.0
WLSH2_k127_5699450_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003747 252.0
WLSH2_k127_5699450_7 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000001069 244.0
WLSH2_k127_5699450_8 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000413 244.0
WLSH2_k127_5699450_9 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000001391 206.0
WLSH2_k127_5715233_0 Belongs to the TPP enzyme family K04103 - 4.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 460.0
WLSH2_k127_5715233_1 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 303.0
WLSH2_k127_5715233_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 300.0
WLSH2_k127_5715233_3 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000001703 198.0
WLSH2_k127_5715233_4 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.0000000000000000000000000001866 122.0
WLSH2_k127_5715233_5 DNA-binding protein VF530 - - - 0.0000000000000000000000000008672 114.0
WLSH2_k127_5715233_6 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000000009662 106.0
WLSH2_k127_5715233_7 COG0724 RNA-binding proteins (RRM domain) - - - 0.000000000000000007071 87.0
WLSH2_k127_5715233_8 Helix-turn-helix K07726 - - 0.00000000000000003675 85.0
WLSH2_k127_5841594_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1519.0
WLSH2_k127_5841594_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1124.0
WLSH2_k127_5841594_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 457.0
WLSH2_k127_5841594_11 TIGRFAM Drug resistance transporter Bcr CflA subfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 452.0
WLSH2_k127_5841594_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 430.0
WLSH2_k127_5841594_13 Major facilitator superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 430.0
WLSH2_k127_5841594_14 Flagellar basal body protein FlaE K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 444.0
WLSH2_k127_5841594_15 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 398.0
WLSH2_k127_5841594_16 hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 377.0
WLSH2_k127_5841594_17 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 337.0
WLSH2_k127_5841594_18 Transcriptional regulator K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 328.0
WLSH2_k127_5841594_19 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 302.0
WLSH2_k127_5841594_2 cation transport ATPase K17686 - 3.6.3.54 2.128e-293 919.0
WLSH2_k127_5841594_20 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 312.0
WLSH2_k127_5841594_21 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 301.0
WLSH2_k127_5841594_22 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 293.0
WLSH2_k127_5841594_23 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 294.0
WLSH2_k127_5841594_24 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 271.0
WLSH2_k127_5841594_25 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005769 267.0
WLSH2_k127_5841594_26 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001771 233.0
WLSH2_k127_5841594_27 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000005775 209.0
WLSH2_k127_5841594_28 SapC - - - 0.000000000000000000000000000000000000000000000000000001304 201.0
WLSH2_k127_5841594_29 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000005013 184.0
WLSH2_k127_5841594_3 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 1.464e-275 887.0
WLSH2_k127_5841594_30 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000002198 171.0
WLSH2_k127_5841594_31 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000006992 162.0
WLSH2_k127_5841594_32 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000244 162.0
WLSH2_k127_5841594_33 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000611 152.0
WLSH2_k127_5841594_34 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000003207 141.0
WLSH2_k127_5841594_35 Histidine kinase - - - 0.0000000000000000000000000000000003659 138.0
WLSH2_k127_5841594_36 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.00000000000000000000000000000000247 132.0
WLSH2_k127_5841594_37 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000006331 136.0
WLSH2_k127_5841594_38 response regulator - - - 0.000000000000000000000000000000836 130.0
WLSH2_k127_5841594_39 AAA domain K00663,K07028 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0009987,GO:0030312,GO:0044464,GO:0044764,GO:0046812,GO:0051704,GO:0071944 2.3.1.82 0.0000000000000000000000000001415 122.0
WLSH2_k127_5841594_4 Multicopper oxidase - - - 6.953e-244 766.0
WLSH2_k127_5841594_40 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000004027 111.0
WLSH2_k127_5841594_41 protein conserved in bacteria - - - 0.0000000000000000000000003907 106.0
WLSH2_k127_5841594_42 23S rRNA-intervening sequence protein - - - 0.00000000000000000000005909 100.0
WLSH2_k127_5841594_43 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000000000003727 102.0
WLSH2_k127_5841594_44 Acetyltransferase (GNAT) domain - - - 0.00000000000000000002404 97.0
WLSH2_k127_5841594_45 - - - - 0.0000000000000001051 82.0
WLSH2_k127_5841594_46 Protein of unknown function (DUF3309) - - - 0.0000000000000002626 79.0
WLSH2_k127_5841594_47 transcriptional - - - 0.0000000000000006703 86.0
WLSH2_k127_5841594_48 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000178 78.0
WLSH2_k127_5841594_49 Collagen triple helix repeat (20 copies) - - - 0.000000000000009981 78.0
WLSH2_k127_5841594_5 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.19e-219 689.0
WLSH2_k127_5841594_50 Predicted integral membrane protein (DUF2282) - - - 0.00000000000001197 79.0
WLSH2_k127_5841594_51 Belongs to the UPF0337 (CsbD) family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000006548 75.0
WLSH2_k127_5841594_52 Leucine Rich repeat - - - 0.000000000003179 78.0
WLSH2_k127_5841594_54 Flagellar hook-length control protein K10565 - - 0.000000000151 74.0
WLSH2_k127_5841594_55 ribosome binding - - - 0.0000000003755 63.0
WLSH2_k127_5841594_56 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) K20978 - - 0.0000000004926 64.0
WLSH2_k127_5841594_59 UPF0391 membrane protein - - - 0.00000009578 55.0
WLSH2_k127_5841594_6 carbamoyl-phosphate synthetase glutamine chain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007363 587.0
WLSH2_k127_5841594_60 - - - - 0.000002566 51.0
WLSH2_k127_5841594_61 anti-sigma-factor antagonist K20978 - - 0.000006696 52.0
WLSH2_k127_5841594_62 - - - - 0.00001351 53.0
WLSH2_k127_5841594_63 Helix-turn-helix XRE-family like proteins - - - 0.0002309 48.0
WLSH2_k127_5841594_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 508.0
WLSH2_k127_5841594_8 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006532 480.0
WLSH2_k127_5841594_9 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 483.0
WLSH2_k127_6228342_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.109e-319 989.0
WLSH2_k127_6228342_1 Glutamine amidotransferase domain K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.132e-261 819.0
WLSH2_k127_6228342_10 COG1587 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000009523 148.0
WLSH2_k127_6228342_11 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000355 143.0
WLSH2_k127_6228342_12 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000001956 116.0
WLSH2_k127_6228342_13 PAS domain - - - 0.000000003482 64.0
WLSH2_k127_6228342_14 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000003901 62.0
WLSH2_k127_6228342_2 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 520.0
WLSH2_k127_6228342_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 477.0
WLSH2_k127_6228342_4 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 453.0
WLSH2_k127_6228342_5 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 383.0
WLSH2_k127_6228342_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 308.0
WLSH2_k127_6228342_7 HemY domain protein K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000001966 249.0
WLSH2_k127_6228342_8 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000001808 220.0
WLSH2_k127_6228342_9 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000002885 209.0
WLSH2_k127_6804695_0 Polyphosphate kinase N-terminal domain K00937 - 2.7.4.1 1.013e-261 824.0
WLSH2_k127_6804695_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 5.032e-254 808.0
WLSH2_k127_6804695_10 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 315.0
WLSH2_k127_6804695_11 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 312.0
WLSH2_k127_6804695_12 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 289.0
WLSH2_k127_6804695_13 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000939 284.0
WLSH2_k127_6804695_14 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002164 279.0
WLSH2_k127_6804695_15 Chaperone SurA K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001087 207.0
WLSH2_k127_6804695_16 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000004022 200.0
WLSH2_k127_6804695_17 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000003564 154.0
WLSH2_k127_6804695_18 toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000001137 155.0
WLSH2_k127_6804695_19 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000002709 142.0
WLSH2_k127_6804695_2 Belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 2.173e-200 635.0
WLSH2_k127_6804695_20 PhnA domain K06193 - - 0.0000000000000000000000000001849 115.0
WLSH2_k127_6804695_21 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.00000000000000000002759 95.0
WLSH2_k127_6804695_22 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000006871 88.0
WLSH2_k127_6804695_23 COG3232 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.0000000000000000305 86.0
WLSH2_k127_6804695_24 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000815 78.0
WLSH2_k127_6804695_25 Pfam:N_methyl_2 - - - 0.0000000000003634 78.0
WLSH2_k127_6804695_26 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000002088 70.0
WLSH2_k127_6804695_27 - - - - 0.0000000005509 65.0
WLSH2_k127_6804695_28 - - - - 0.0000003431 59.0
WLSH2_k127_6804695_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 548.0
WLSH2_k127_6804695_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 501.0
WLSH2_k127_6804695_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 494.0
WLSH2_k127_6804695_6 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 486.0
WLSH2_k127_6804695_7 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 449.0
WLSH2_k127_6804695_8 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 396.0
WLSH2_k127_6804695_9 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 352.0
WLSH2_k127_6805948_0 Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296 - - 0.0 1373.0
WLSH2_k127_6805948_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 9.558e-310 980.0
WLSH2_k127_6805948_10 COG0694 Thioredoxin-like proteins and domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000005874 232.0
WLSH2_k127_6805948_11 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000001921 216.0
WLSH2_k127_6805948_12 Filamentation induced by cAMP protein fic - - - 0.000000000000000000000000000001973 125.0
WLSH2_k127_6805948_13 Diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000003498 106.0
WLSH2_k127_6805948_14 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000002845 97.0
WLSH2_k127_6805948_15 - - - - 0.00000000000000001075 92.0
WLSH2_k127_6805948_16 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00004334 56.0
WLSH2_k127_6805948_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.281e-218 686.0
WLSH2_k127_6805948_3 Aminotransferase class-III K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 531.0
WLSH2_k127_6805948_4 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 521.0
WLSH2_k127_6805948_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 476.0
WLSH2_k127_6805948_6 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 441.0
WLSH2_k127_6805948_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0006855,GO:0006869,GO:0008150,GO:0010876,GO:0015238,GO:0015711,GO:0015718,GO:0015721,GO:0015849,GO:0015850,GO:0015893,GO:0016020,GO:0022857,GO:0031224,GO:0031226,GO:0033036,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 371.0
WLSH2_k127_6805948_8 RadC-like JAB domain K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001976 271.0
WLSH2_k127_6805948_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002535 244.0
WLSH2_k127_7246950_0 P-type ATPase' K01533 - 3.6.3.4 4.502e-277 872.0
WLSH2_k127_7246950_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.416e-273 845.0
WLSH2_k127_7246950_2 Cytochrome c oxidase accessory protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 3.748e-213 670.0
WLSH2_k127_7246950_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 422.0
WLSH2_k127_7246950_4 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 395.0
WLSH2_k127_7246950_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000002365 228.0
WLSH2_k127_7246950_6 FixH - - - 0.00000000000000000000000000000000000002441 149.0
WLSH2_k127_7246950_7 Cytochrome oxidase maturation protein - - - 0.00000000000000006007 81.0
WLSH2_k127_7323871_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 1.681e-233 736.0
WLSH2_k127_7323871_1 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000005248 153.0
WLSH2_k127_7323871_2 PFAM plasmid encoded RepA protein - - - 0.0000000000000000000000008318 119.0
WLSH2_k127_7323871_3 IS2 (IS982-family) - - - 0.0000000909 54.0
WLSH2_k127_7323871_4 osmolarity-sensing cation channel activity K04984 GO:0000302,GO:0001580,GO:0002791,GO:0002793,GO:0003008,GO:0003012,GO:0003674,GO:0004888,GO:0005034,GO:0005215,GO:0005216,GO:0005217,GO:0005244,GO:0005245,GO:0005261,GO:0005262,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0006936,GO:0006939,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007166,GO:0007204,GO:0007600,GO:0007602,GO:0007606,GO:0007610,GO:0007638,GO:0008150,GO:0008324,GO:0009266,GO:0009314,GO:0009408,GO:0009409,GO:0009410,GO:0009416,GO:0009453,GO:0009581,GO:0009582,GO:0009583,GO:0009593,GO:0009605,GO:0009612,GO:0009628,GO:0009636,GO:0009719,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010035,GO:0010037,GO:0010243,GO:0010378,GO:0010646,GO:0010647,GO:0010817,GO:0014070,GO:0014074,GO:0014832,GO:0014848,GO:0015075,GO:0015085,GO:0015267,GO:0015276,GO:0015278,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0016048,GO:0016324,GO:0019233,GO:0019722,GO:0019725,GO:0019932,GO:0022607,GO:0022803,GO:0022832,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0023041,GO:0023051,GO:0023052,GO:0023056,GO:0030001,GO:0030003,GO:0030424,GO:0031000,GO:0031224,GO:0031226,GO:0031644,GO:0031646,GO:0032024,GO:0032421,GO:0032501,GO:0032879,GO:0032880,GO:0032991,GO:0033554,GO:0033555,GO:0034220,GO:0034605,GO:0034702,GO:0034703,GO:0035556,GO:0035690,GO:0035774,GO:0036270,GO:0038023,GO:0040011,GO:0040040,GO:0042221,GO:0042330,GO:0042331,GO:0042391,GO:0042493,GO:0042542,GO:0042592,GO:0042752,GO:0042802,GO:0042995,GO:0043005,GO:0043052,GO:0043269,GO:0043270,GO:0043279,GO:0043933,GO:0044057,GO:0044070,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045177,GO:0046677,GO:0046873,GO:0046883,GO:0046887,GO:0046957,GO:0048265,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048878,GO:0050708,GO:0050714,GO:0050789,GO:0050794,GO:0050796,GO:0050801,GO:0050848,GO:0050850,GO:0050877,GO:0050896,GO:0050906,GO:0050907,GO:0050909,GO:0050912,GO:0050913,GO:0050951,GO:0050954,GO:0050955,GO:0050960,GO:0050961,GO:0050965,GO:0050966,GO:0050968,GO:0050974,GO:0050982,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051179,GO:0051209,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051240,GO:0051259,GO:0051260,GO:0051262,GO:0051282,GO:0051283,GO:0051289,GO:0051480,GO:0051606,GO:0051641,GO:0051649,GO:0051716,GO:0051930,GO:0051931,GO:0051969,GO:0052129,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0060089,GO:0060341,GO:0060401,GO:0060402,GO:0061178,GO:0065003,GO:0065007,GO:0065008,GO:0070201,GO:0070417,GO:0070588,GO:0070838,GO:0070887,GO:0071241,GO:0071244,GO:0071310,GO:0071312,GO:0071313,GO:0071407,GO:0071415,GO:0071417,GO:0071466,GO:0071495,GO:0071840,GO:0071944,GO:0072347,GO:0072503,GO:0072507,GO:0072511,GO:0090087,GO:0090276,GO:0090277,GO:0097458,GO:0097553,GO:0097603,GO:0097604,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098796,GO:0098862,GO:0098900,GO:0098908,GO:0099094,GO:0099604,GO:0120025,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902495,GO:1902531,GO:1902533,GO:1903522,GO:1903530,GO:1903532,GO:1903793,GO:1904058,GO:1904951,GO:1990351,GO:1990760 - 0.00004859 54.0
WLSH2_k127_7750583_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 583.0
WLSH2_k127_7750583_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 406.0
WLSH2_k127_7750583_10 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000003155 178.0
WLSH2_k127_7750583_11 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000000000001855 154.0
WLSH2_k127_7750583_12 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000001547 142.0
WLSH2_k127_7750583_13 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000216 123.0
WLSH2_k127_7750583_14 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000427 100.0
WLSH2_k127_7750583_2 Histidine kinase K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 372.0
WLSH2_k127_7750583_3 Cytosine-specific methyltransferase K00558 - 2.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 361.0
WLSH2_k127_7750583_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 348.0
WLSH2_k127_7750583_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001814 269.0
WLSH2_k127_7750583_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001877 247.0
WLSH2_k127_7750583_7 Role in flagellar biosynthesis K02421 - - 0.00000000000000000000000000000000000000000000000000000004026 206.0
WLSH2_k127_7750583_8 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000297 197.0
WLSH2_k127_7750583_9 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000001197 173.0
WLSH2_k127_7938270_0 This protein is involved in the repair of mismatches in DNA K03555 - - 3.672e-305 959.0
WLSH2_k127_7938270_1 PFAM pfkB family carbohydrate kinase K00847,K00856 - 2.7.1.20,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 353.0
WLSH2_k127_7938270_11 COG2885 outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.000008724 59.0
WLSH2_k127_7938270_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002002 259.0
WLSH2_k127_7938270_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000001233 256.0
WLSH2_k127_7938270_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000005866 224.0
WLSH2_k127_7938270_5 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000004091 207.0
WLSH2_k127_7938270_6 Aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000001835 170.0
WLSH2_k127_7938270_7 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000002567 145.0
WLSH2_k127_7938270_8 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000009682 91.0
WLSH2_k127_7938270_9 Bacterial PH domain K08981 - - 0.000000001003 68.0
WLSH2_k127_7939470_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1200.0
WLSH2_k127_7939470_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1016.0
WLSH2_k127_7939470_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000007004 262.0
WLSH2_k127_7939470_11 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001245 256.0
WLSH2_k127_7939470_12 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000001755 262.0
WLSH2_k127_7939470_13 Type IV secretory pathway, VirB9 components K03204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004725 257.0
WLSH2_k127_7939470_14 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000006617 229.0
WLSH2_k127_7939470_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002324 217.0
WLSH2_k127_7939470_16 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000001976 224.0
WLSH2_k127_7939470_17 Domain of unknown function (DUF3576) - - - 0.00000000000000000000000000000000000002486 151.0
WLSH2_k127_7939470_18 Type IV secretory pathway, component VirB8 K03203 - - 0.000000000000000000000000005396 119.0
WLSH2_k127_7939470_19 Ankyrin repeats (3 copies) - - - 0.0000000000000000000006257 108.0
WLSH2_k127_7939470_2 COG1157 Flagellar biosynthesis type III secretory pathway ATPase K02412 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 611.0
WLSH2_k127_7939470_20 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000108 91.0
WLSH2_k127_7939470_21 Pfam:N_methyl_2 - - - 0.00000000000004163 81.0
WLSH2_k127_7939470_22 Lipopolysaccharide-assembly K03643 - - 0.0000000002611 69.0
WLSH2_k127_7939470_23 - - - - 0.00000005589 60.0
WLSH2_k127_7939470_3 acetylornithine aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 470.0
WLSH2_k127_7939470_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 386.0
WLSH2_k127_7939470_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 360.0
WLSH2_k127_7939470_6 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 364.0
WLSH2_k127_7939470_7 Iron-containing alcohol dehydrogenase K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 354.0
WLSH2_k127_7939470_8 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0015976,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036307,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001238 279.0
WLSH2_k127_7939470_9 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001917 276.0
WLSH2_k127_8386705_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1049.0
WLSH2_k127_8386705_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.398e-294 917.0
WLSH2_k127_8386705_10 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 599.0
WLSH2_k127_8386705_101 Rod binding protein - - - 0.0000000009447 65.0
WLSH2_k127_8386705_102 - - - - 0.000000004642 64.0
WLSH2_k127_8386705_103 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000008401 60.0
WLSH2_k127_8386705_104 Protein of unknown function (DUF465) - - - 0.00000002972 57.0
WLSH2_k127_8386705_105 - - - - 0.0000008862 55.0
WLSH2_k127_8386705_106 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000001185 57.0
WLSH2_k127_8386705_107 general secretion pathway protein - - - 0.000007059 60.0
WLSH2_k127_8386705_108 Pentapeptide repeats (9 copies) - - - 0.0001171 52.0
WLSH2_k127_8386705_11 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 578.0
WLSH2_k127_8386705_12 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 549.0
WLSH2_k127_8386705_13 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 525.0
WLSH2_k127_8386705_14 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 501.0
WLSH2_k127_8386705_15 Trypsin K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006508,GO:0006515,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030163,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051603,GO:0061077,GO:0070011,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 467.0
WLSH2_k127_8386705_16 de-polymerase K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 453.0
WLSH2_k127_8386705_17 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 439.0
WLSH2_k127_8386705_18 NAD(P) transhydrogenase, alpha subunit K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 422.0
WLSH2_k127_8386705_19 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 400.0
WLSH2_k127_8386705_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 7.423e-272 865.0
WLSH2_k127_8386705_20 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 395.0
WLSH2_k127_8386705_21 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 393.0
WLSH2_k127_8386705_22 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 393.0
WLSH2_k127_8386705_23 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 367.0
WLSH2_k127_8386705_24 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 368.0
WLSH2_k127_8386705_25 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 362.0
WLSH2_k127_8386705_26 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 365.0
WLSH2_k127_8386705_27 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 366.0
WLSH2_k127_8386705_28 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 365.0
WLSH2_k127_8386705_29 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 359.0
WLSH2_k127_8386705_3 transport system, fused permease components - - - 2.155e-268 852.0
WLSH2_k127_8386705_30 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 344.0
WLSH2_k127_8386705_31 flagellar hook-associated protein K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 360.0
WLSH2_k127_8386705_32 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 329.0
WLSH2_k127_8386705_33 Protein of unknown function (DUF3179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 319.0
WLSH2_k127_8386705_34 CoA-transferase activity K01027,K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 313.0
WLSH2_k127_8386705_35 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 310.0
WLSH2_k127_8386705_36 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 304.0
WLSH2_k127_8386705_37 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008 300.0
WLSH2_k127_8386705_38 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 290.0
WLSH2_k127_8386705_39 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 284.0
WLSH2_k127_8386705_4 helicase - - - 5.922e-242 758.0
WLSH2_k127_8386705_40 QueF-like protein K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000003371 263.0
WLSH2_k127_8386705_41 COG0515 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009819 287.0
WLSH2_k127_8386705_42 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006178 259.0
WLSH2_k127_8386705_43 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000008805 269.0
WLSH2_k127_8386705_44 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000246 253.0
WLSH2_k127_8386705_45 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006694 259.0
WLSH2_k127_8386705_46 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000218 253.0
WLSH2_k127_8386705_47 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002922 246.0
WLSH2_k127_8386705_48 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000007681 235.0
WLSH2_k127_8386705_49 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
WLSH2_k127_8386705_5 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.134e-237 744.0
WLSH2_k127_8386705_50 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000005931 228.0
WLSH2_k127_8386705_51 PFAM Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000001085 221.0
WLSH2_k127_8386705_52 flagellar motor component K02556 - - 0.0000000000000000000000000000000000000000000000000000000000001881 220.0
WLSH2_k127_8386705_53 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000001224 215.0
WLSH2_k127_8386705_54 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000003922 203.0
WLSH2_k127_8386705_55 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000006435 201.0
WLSH2_k127_8386705_56 ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000003184 198.0
WLSH2_k127_8386705_57 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000003099 194.0
WLSH2_k127_8386705_58 - - - - 0.0000000000000000000000000000000000000000000000006849 178.0
WLSH2_k127_8386705_59 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000007829 181.0
WLSH2_k127_8386705_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.011e-230 727.0
WLSH2_k127_8386705_60 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000909 190.0
WLSH2_k127_8386705_61 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000001492 177.0
WLSH2_k127_8386705_62 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000002366 170.0
WLSH2_k127_8386705_63 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000006504 158.0
WLSH2_k127_8386705_64 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000007329 154.0
WLSH2_k127_8386705_65 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000001575 151.0
WLSH2_k127_8386705_66 flagellar motor protein K02557 - - 0.0000000000000000000000000000000000004005 149.0
WLSH2_k127_8386705_67 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000007143 146.0
WLSH2_k127_8386705_68 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.000000000000000000000000000000000004917 148.0
WLSH2_k127_8386705_69 protein conserved in bacteria K01876 - 6.1.1.12 0.00000000000000000000000000000000001501 141.0
WLSH2_k127_8386705_7 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 1.127e-227 712.0
WLSH2_k127_8386705_70 Sporulation related domain K01679 - 4.2.1.2 0.0000000000000000000000000000000003933 145.0
WLSH2_k127_8386705_71 Ankyrin repeat K15502,K15503,K15504 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006810,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016050,GO:0016192,GO:0022607,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0051179,GO:0051234,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0061024,GO:0065003,GO:0070013,GO:0071840,GO:0090114 - 0.000000000000000000000000000000001145 141.0
WLSH2_k127_8386705_72 spectrin binding K15503 - - 0.000000000000000000000000000000002036 145.0
WLSH2_k127_8386705_73 addiction module antidote protein HigA - - - 0.0000000000000000000000000000006647 125.0
WLSH2_k127_8386705_74 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000006772 130.0
WLSH2_k127_8386705_75 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000005083 122.0
WLSH2_k127_8386705_76 ETC complex I subunit conserved region K00329 - 1.6.5.3 0.000000000000000000000000000005272 123.0
WLSH2_k127_8386705_77 amine dehydrogenase activity - - - 0.00000000000000000000000000008502 134.0
WLSH2_k127_8386705_78 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.000000000000000000000001032 107.0
WLSH2_k127_8386705_79 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000001073 114.0
WLSH2_k127_8386705_8 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 3.69e-219 687.0
WLSH2_k127_8386705_80 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000145 105.0
WLSH2_k127_8386705_81 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000001906 105.0
WLSH2_k127_8386705_82 Plasmid stabilization system - - - 0.0000000000000000000009303 98.0
WLSH2_k127_8386705_83 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000007668 102.0
WLSH2_k127_8386705_84 domain, Protein K07654 - 2.7.13.3 0.00000000000000000002394 108.0
WLSH2_k127_8386705_85 Belongs to the UPF0434 family K09791 - - 0.000000000000000001812 86.0
WLSH2_k127_8386705_86 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 GO:0003674,GO:0003824,GO:0004617,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0047545,GO:0055114,GO:0070905,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.399,1.1.1.95 0.00000000000000002015 98.0
WLSH2_k127_8386705_87 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000002284 98.0
WLSH2_k127_8386705_88 YGGT family K02221 - - 0.00000000000000003702 84.0
WLSH2_k127_8386705_89 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000008766 82.0
WLSH2_k127_8386705_9 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 3.169e-202 639.0
WLSH2_k127_8386705_90 general secretion pathway protein - - - 0.0000000000000001158 94.0
WLSH2_k127_8386705_91 Class II flagellar assembly regulator - - - 0.0000000000000002426 84.0
WLSH2_k127_8386705_92 TPR repeat - - - 0.000000000000009275 83.0
WLSH2_k127_8386705_93 Ankyrin repeat - - - 0.0000000000000113 86.0
WLSH2_k127_8386705_94 serine threonine protein kinase - - - 0.00000000000001412 83.0
WLSH2_k127_8386705_95 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000356 87.0
WLSH2_k127_8386705_96 TrbC/VIRB2 family - - - 0.0000000000005699 74.0
WLSH2_k127_8386705_97 flagellar protein fliS K02422 GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.0000000000008395 75.0
WLSH2_k127_8386705_98 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000006934 72.0
WLSH2_k127_8386705_99 Ribbon-helix-helix protein, copG family - - - 0.00000000009948 65.0
WLSH2_k127_8718699_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 492.0
WLSH2_k127_8718699_1 Glycosyl transferase family 41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 436.0
WLSH2_k127_8718699_10 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.000000000001156 71.0
WLSH2_k127_8718699_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
WLSH2_k127_8718699_3 DNA recombination protein RmuC homolog K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000002148 254.0
WLSH2_k127_8718699_4 Methyl-accepting chemotaxis protein (MCP) signalling domain - - - 0.00000000000000000000000000000000000000000000000000005036 192.0
WLSH2_k127_8718699_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000003418 104.0
WLSH2_k127_8718699_6 YoeB-like toxin of bacterial type II toxin-antitoxin system K19158 - - 0.0000000000000000000001482 101.0
WLSH2_k127_8718699_7 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001223 88.0
WLSH2_k127_8718699_8 Helix-turn-helix XRE-family like proteins K07726 - - 0.0000000000002157 74.0
WLSH2_k127_8718699_9 zinc-ribbon domain - - - 0.000000000000781 77.0
WLSH2_k127_8833985_0 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 1.805e-238 751.0
WLSH2_k127_8833985_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 602.0
WLSH2_k127_8833985_10 Septum formation initiator - - - 0.000000000000000001156 90.0
WLSH2_k127_8833985_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 527.0
WLSH2_k127_8833985_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 456.0
WLSH2_k127_8833985_4 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 379.0
WLSH2_k127_8833985_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001887 275.0
WLSH2_k127_8833985_6 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000172 152.0
WLSH2_k127_8833985_7 metalloendopeptidase activity K03799,K06013 - 3.4.24.84 0.0000000000000000000000000000805 129.0
WLSH2_k127_8833985_8 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000001624 127.0
WLSH2_k127_8833985_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000002383 108.0
WLSH2_k127_8875785_0 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007889 273.0
WLSH2_k127_8875785_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.00000000000000000000000000000000000000000000001141 176.0
WLSH2_k127_8875785_2 protein conserved in bacteria K09985 - - 0.000000000000000000000000000000000000000000005062 169.0
WLSH2_k127_8875785_3 Type II/IV secretion system protein K02454 - - 0.0000000000000000000000000003085 121.0
WLSH2_k127_8875785_4 Protein of unknown function (DUF3137) - - - 0.0000000000035 78.0
WLSH2_k127_8998046_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 556.0
WLSH2_k127_8998046_1 Potassium transporter peripheral membrane component K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 530.0
WLSH2_k127_8998046_2 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 510.0
WLSH2_k127_8998046_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 443.0
WLSH2_k127_8998046_4 Amino-transferase class IV K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000001798 256.0
WLSH2_k127_8998046_5 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000004827 246.0
WLSH2_k127_8998046_6 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003787 244.0
WLSH2_k127_8998046_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000267 172.0
WLSH2_k127_9138059_0 DNA integration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 393.0
WLSH2_k127_9138059_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000007877 184.0
WLSH2_k127_9138059_2 PFAM Transposase - - - 0.000000006342 57.0
WLSH2_k127_934394_0 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 572.0
WLSH2_k127_934394_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 567.0
WLSH2_k127_934394_10 a g-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 336.0
WLSH2_k127_934394_11 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000007069 232.0
WLSH2_k127_934394_12 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000004884 184.0
WLSH2_k127_934394_13 Bacterial-like globin - - - 0.000000000000000000000000000000000001094 141.0
WLSH2_k127_934394_14 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000003473 132.0
WLSH2_k127_934394_15 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000000000000000000008356 127.0
WLSH2_k127_934394_16 - - - - 0.000000000000000000000000008631 111.0
WLSH2_k127_934394_17 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.00000000000000000000000002977 117.0
WLSH2_k127_934394_18 sequence-specific DNA binding - - - 0.000000000000000000000003352 106.0
WLSH2_k127_934394_19 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000006467 105.0
WLSH2_k127_934394_2 transport system, permease component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 538.0
WLSH2_k127_934394_20 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.0000000000000000468 90.0
WLSH2_k127_934394_21 COG1317 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.000000000000000151 89.0
WLSH2_k127_934394_22 EF-hand domain pair - - - 0.0000000000856 69.0
WLSH2_k127_934394_23 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00007202 54.0
WLSH2_k127_934394_3 ABC transporter permease K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 514.0
WLSH2_k127_934394_4 Pyridoxal-dependent decarboxylase, C-terminal sheet domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 511.0
WLSH2_k127_934394_5 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 477.0
WLSH2_k127_934394_6 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 468.0
WLSH2_k127_934394_7 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide K01479,K01480 - 3.5.3.11,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 452.0
WLSH2_k127_934394_8 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 404.0
WLSH2_k127_934394_9 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 343.0
WLSH2_k127_9364799_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1058.0
WLSH2_k127_9364799_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.004e-219 687.0
WLSH2_k127_9364799_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 395.0
WLSH2_k127_9364799_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 326.0
WLSH2_k127_9364799_4 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003055 245.0
WLSH2_k127_9364799_5 acetyltransferase - - - 0.000000000000000000000000002221 116.0
WLSH2_k127_9402220_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 1e-323 1011.0
WLSH2_k127_9402220_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 2.135e-251 793.0
WLSH2_k127_9402220_10 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 330.0
WLSH2_k127_9402220_11 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 310.0
WLSH2_k127_9402220_12 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 302.0
WLSH2_k127_9402220_13 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 300.0
WLSH2_k127_9402220_14 Belongs to the flagella basal body rod proteins family K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 301.0
WLSH2_k127_9402220_15 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001059 250.0
WLSH2_k127_9402220_16 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001476 246.0
WLSH2_k127_9402220_17 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000001544 242.0
WLSH2_k127_9402220_18 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000001763 261.0
WLSH2_k127_9402220_19 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004632 233.0
WLSH2_k127_9402220_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.124e-207 651.0
WLSH2_k127_9402220_20 water channel activity K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000006275 211.0
WLSH2_k127_9402220_21 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000009313 177.0
WLSH2_k127_9402220_22 Histidine kinase - - - 0.000000000000000000000000000000000000000000000009525 190.0
WLSH2_k127_9402220_23 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.000000000000000000000000000000000000000000738 160.0
WLSH2_k127_9402220_24 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000000000000000003474 162.0
WLSH2_k127_9402220_25 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000004755 156.0
WLSH2_k127_9402220_26 Belongs to the flagella basal body rod proteins family K02391 - - 0.0000000000000000000000000000000000000001207 160.0
WLSH2_k127_9402220_27 CopG-like RHH_1 or ribbon-helix-helix domain, RHH_5 - - - 0.00000000000000000000000000000000000004754 147.0
WLSH2_k127_9402220_28 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000001251 145.0
WLSH2_k127_9402220_29 Flagellar basal body-associated protein FliL K02415 - - 0.0000000000000000000000000000000000002459 148.0
WLSH2_k127_9402220_3 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 555.0
WLSH2_k127_9402220_30 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000001042 147.0
WLSH2_k127_9402220_31 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.00000000000000000000000000000000000381 146.0
WLSH2_k127_9402220_32 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000002031 131.0
WLSH2_k127_9402220_33 MgtE intracellular N domain - - - 0.000000000000000000000000000000003049 138.0
WLSH2_k127_9402220_35 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000000000000000000000000157 111.0
WLSH2_k127_9402220_36 COG3143 Chemotaxis protein K03414 - - 0.0000000000000000000000000574 115.0
WLSH2_k127_9402220_37 Histidine Phosphotransfer domain - - - 0.0000000000000000000007853 106.0
WLSH2_k127_9402220_38 - - - - 0.00000000000000000009783 91.0
WLSH2_k127_9402220_39 cheY-homologous receiver domain K03413 - - 0.000000000000000002182 89.0
WLSH2_k127_9402220_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 507.0
WLSH2_k127_9402220_40 Flagellar biosynthesis protein, FliO K02418 - - 0.00000000000000001039 87.0
WLSH2_k127_9402220_41 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000007291 82.0
WLSH2_k127_9402220_42 Domain of unknown function (DUF4154) - - - 0.000000000000003509 83.0
WLSH2_k127_9402220_43 Prepilin-type N-terminal cleavage methylation domain-containing protein - - - 0.000000000000004876 85.0
WLSH2_k127_9402220_44 Flagellar basal body P-ring biosynthesis protein K02386 - - 0.0000000000001107 81.0
WLSH2_k127_9402220_45 - - - - 0.000000000009817 73.0
WLSH2_k127_9402220_46 Protein of unknown function (DUF2671) - - - 0.00000000002416 67.0
WLSH2_k127_9402220_47 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000004885 65.0
WLSH2_k127_9402220_48 PFAM YcfA family protein - - - 0.00000001737 55.0
WLSH2_k127_9402220_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 503.0
WLSH2_k127_9402220_50 - - - - 0.000007923 49.0
WLSH2_k127_9402220_51 Chemotaxis MotB protein K02557 - - 0.00001497 57.0
WLSH2_k127_9402220_6 Sigma-54 interaction domain - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 490.0
WLSH2_k127_9402220_7 SEFIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 438.0
WLSH2_k127_9402220_8 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 424.0
WLSH2_k127_9402220_9 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 393.0
WLSH2_k127_9458599_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.123e-281 878.0
WLSH2_k127_9458599_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.916e-201 636.0
WLSH2_k127_9458599_10 PFAM binding-protein-dependent transport systems inner membrane component K02046,K15496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 375.0
WLSH2_k127_9458599_11 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 368.0
WLSH2_k127_9458599_12 Zn-dependent protease, contains TPR repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 370.0
WLSH2_k127_9458599_13 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 346.0
WLSH2_k127_9458599_14 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 334.0
WLSH2_k127_9458599_15 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 319.0
WLSH2_k127_9458599_16 Ribosomal protein L11 methyltransferase (PrmA) K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 280.0
WLSH2_k127_9458599_17 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 257.0
WLSH2_k127_9458599_18 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000008227 217.0
WLSH2_k127_9458599_19 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
WLSH2_k127_9458599_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 501.0
WLSH2_k127_9458599_20 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000000000007786 212.0
WLSH2_k127_9458599_21 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000009814 199.0
WLSH2_k127_9458599_22 Rrf2 family - - - 0.000000000000000000000000000000000000000000000000001864 185.0
WLSH2_k127_9458599_23 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000005785 183.0
WLSH2_k127_9458599_24 Domain of unknown function (DUF1956) - - - 0.00000000000000000000000000000000000000000000009633 177.0
WLSH2_k127_9458599_25 ECF sigma factor - - - 0.0000000000000000000000000000000000000000009351 164.0
WLSH2_k127_9458599_26 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.00000000000000000000000000000000000003714 148.0
WLSH2_k127_9458599_27 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000004166 144.0
WLSH2_k127_9458599_28 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000001256 138.0
WLSH2_k127_9458599_29 universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000001648 101.0
WLSH2_k127_9458599_3 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 493.0
WLSH2_k127_9458599_30 - - - - 0.00000000001741 76.0
WLSH2_k127_9458599_31 PFAM Pentapeptide repeats (8 copies) - - - 0.00000001285 66.0
WLSH2_k127_9458599_32 Domain of unknown function (DUF4167) - - - 0.000009325 55.0
WLSH2_k127_9458599_33 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00002025 51.0
WLSH2_k127_9458599_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 484.0
WLSH2_k127_9458599_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 473.0
WLSH2_k127_9458599_6 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 468.0
WLSH2_k127_9458599_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 432.0
WLSH2_k127_9458599_8 Part of the ABC transporter complex cysAWTP involved in sulfate thiosulfate import K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 403.0
WLSH2_k127_9458599_9 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 406.0
WLSH2_k127_947306_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1426.0
WLSH2_k127_947306_1 Adenylylsulphate kinase K00955 - 2.7.1.25,2.7.7.4 1.679e-255 803.0
WLSH2_k127_947306_10 Domain of unknown function (DUF4276) - - - 0.000000000000000000000000000000000000000000000000009276 188.0
WLSH2_k127_947306_11 Sirohaem biosynthesis protein central - - - 0.000000000000000000000000000000000000000000000002402 180.0
WLSH2_k127_947306_12 Polyribonucleotide nucleotidyltransferase - - - 0.00000000000000000000000000007835 119.0
WLSH2_k127_947306_13 Cold shock K03704 - - 0.0000000000000000000000000003737 114.0
WLSH2_k127_947306_14 Domain of unknown function (DUF4402) - - - 0.00000001409 63.0
WLSH2_k127_947306_15 - - - - 0.0006794 49.0
WLSH2_k127_947306_2 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 1.331e-199 637.0
WLSH2_k127_947306_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 542.0
WLSH2_k127_947306_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 440.0
WLSH2_k127_947306_5 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 376.0
WLSH2_k127_947306_6 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 363.0
WLSH2_k127_947306_7 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000469 225.0
WLSH2_k127_947306_8 COG3121 P pilus assembly protein, chaperone PapD - - - 0.0000000000000000000000000000000000000000000000000000000000002167 223.0
WLSH2_k127_947306_9 Adenosine/AMP deaminase K13988 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000003531 219.0
WLSH2_k127_9633524_0 Type II/IV secretion system protein K02652 - - 1.888e-197 625.0
WLSH2_k127_9633524_1 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 447.0
WLSH2_k127_9633524_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 381.0
WLSH2_k127_9633524_3 ABC transporter K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003412 262.0
WLSH2_k127_9633524_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000001468 239.0
WLSH2_k127_9633524_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000003513 142.0
WLSH2_k127_9633524_6 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000003343 111.0
WLSH2_k127_9638920_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1015.0
WLSH2_k127_9638920_1 CHASE2 K01768 - 4.6.1.1 5.359e-200 647.0
WLSH2_k127_9638920_10 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000184 197.0
WLSH2_k127_9638920_11 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000008109 176.0
WLSH2_k127_9638920_12 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000001922 173.0
WLSH2_k127_9638920_13 FecR protein - - - 0.000000000000000000000000000009298 138.0
WLSH2_k127_9638920_14 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000001968 112.0
WLSH2_k127_9638920_15 Bacterial protein of unknown function (DUF922) - - - 0.000000000000000000000000003004 120.0
WLSH2_k127_9638920_16 Tellurite resistance protein TerB K05801 - - 0.00000000000000000000000004186 117.0
WLSH2_k127_9638920_17 IS2 (IS982-family) - - - 0.000000000000000000000000473 105.0
WLSH2_k127_9638920_18 Domain of unknown function (DUF1476) - - - 0.0000000000000000000007405 98.0
WLSH2_k127_9638920_19 Tetratricopeptide repeat - - - 0.000000000000000000002142 98.0
WLSH2_k127_9638920_2 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 370.0
WLSH2_k127_9638920_20 Protein of unknown function (DUF560) - - - 0.00000000000000000002674 106.0
WLSH2_k127_9638920_21 chemotaxis protein K03413 - - 0.0000000000000000006405 91.0
WLSH2_k127_9638920_23 PFAM Cyclic nucleotide-binding K03321,K10914 - - 0.000000000000007633 81.0
WLSH2_k127_9638920_24 - - - - 0.0000000000009206 73.0
WLSH2_k127_9638920_25 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000023 74.0
WLSH2_k127_9638920_26 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000001512 68.0
WLSH2_k127_9638920_27 pilus assembly protein PilW K02672 - - 0.0000000001748 70.0
WLSH2_k127_9638920_28 Cyclic nucleotide binding domain protein - - - 0.000000005646 64.0
WLSH2_k127_9638920_29 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000001038 62.0
WLSH2_k127_9638920_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 356.0
WLSH2_k127_9638920_30 Tfp pilus assembly protein K02655 - - 0.0000001072 59.0
WLSH2_k127_9638920_31 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.0000006956 61.0
WLSH2_k127_9638920_32 Tetratricopeptide repeat - - - 0.0000007281 62.0
WLSH2_k127_9638920_33 type IV pilus modification protein PilV - - - 0.0001576 49.0
WLSH2_k127_9638920_4 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 357.0
WLSH2_k127_9638920_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 294.0
WLSH2_k127_9638920_6 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009034 277.0
WLSH2_k127_9638920_7 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000001583 243.0
WLSH2_k127_9638920_8 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000001346 222.0
WLSH2_k127_9638920_9 Pilus assembly protein K02662,K02663 - - 0.00000000000000000000000000000000000000000000000000000199 215.0
WLSH2_k127_9713149_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.835e-288 900.0
WLSH2_k127_9713149_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.958e-287 901.0
WLSH2_k127_9713149_10 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002569 277.0
WLSH2_k127_9713149_11 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
WLSH2_k127_9713149_12 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001102 218.0
WLSH2_k127_9713149_13 Helix-turn-helix domain - - - 0.000000000000000000000000000000000006029 140.0
WLSH2_k127_9713149_14 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000001433 136.0
WLSH2_k127_9713149_15 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000296 135.0
WLSH2_k127_9713149_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000002184 121.0
WLSH2_k127_9713149_17 BolA-like protein K05527,K22066 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:0097428,GO:0106035,GO:1901564 - 0.000000000000000000000008097 103.0
WLSH2_k127_9713149_18 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000006467 72.0
WLSH2_k127_9713149_2 GTP-binding protein TypA K06207 - - 1.395e-284 886.0
WLSH2_k127_9713149_20 - - - - 0.000000009545 59.0
WLSH2_k127_9713149_21 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000002523 67.0
WLSH2_k127_9713149_22 Protein of unknown function (DUF1189) - - - 0.0000001036 64.0
WLSH2_k127_9713149_24 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0003163 53.0
WLSH2_k127_9713149_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 449.0
WLSH2_k127_9713149_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 439.0
WLSH2_k127_9713149_5 alkaline protease secretion ATP-binding protein K06147,K06148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 409.0
WLSH2_k127_9713149_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 377.0
WLSH2_k127_9713149_7 NAD(P)H quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 347.0
WLSH2_k127_9713149_8 Secretion protein K02022,K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
WLSH2_k127_9713149_9 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 324.0
WLSH2_k127_9740341_0 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 547.0
WLSH2_k127_9740341_1 amino acid carrier protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 499.0
WLSH2_k127_9740341_10 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000000000000000000000000000000000000958 209.0
WLSH2_k127_9740341_11 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
WLSH2_k127_9740341_12 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000001085 196.0
WLSH2_k127_9740341_13 LysR substrate binding domain K04761 - - 0.000000000000000000000000000000000000000000005717 168.0
WLSH2_k127_9740341_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000104 132.0
WLSH2_k127_9740341_15 Endonuclease containing a URI domain K07461 - - 0.00000000000000000007466 91.0
WLSH2_k127_9740341_16 - - - - 0.0000000000001017 76.0
WLSH2_k127_9740341_17 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.0000000909 54.0
WLSH2_k127_9740341_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 444.0
WLSH2_k127_9740341_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 427.0
WLSH2_k127_9740341_4 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 408.0
WLSH2_k127_9740341_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 355.0
WLSH2_k127_9740341_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 347.0
WLSH2_k127_9740341_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003491 266.0
WLSH2_k127_9740341_8 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000003786 243.0
WLSH2_k127_9740341_9 IS2 (IS982-family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004074 237.0