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Overview

ID MAG04226
Name WLSH2_bin.6
Sample SMP0110
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Thiohalomonadales
Family Thiohalomonadaceae
Genus DASWUD01
Species
Assembly information
Completeness (%) 83.68
Contamination (%) 2.03
GC content (%) 63.0
N50 (bp) 4,795
Genome size (bp) 2,276,667

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2381

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10007502_0 Isocitrate dehydrogenase NADP-dependent, monomeric type K00031 - 1.1.1.42 1.632e-308 955.0
WLSH2_k127_10007502_1 HNH nucleases - - - 0.000000000000000000000000000005598 128.0
WLSH2_k127_100606_0 3'-5' exonuclease K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 392.0
WLSH2_k127_100606_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000096 378.0
WLSH2_k127_100606_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 309.0
WLSH2_k127_10074492_0 Belongs to the heme-copper respiratory oxidase family K00404 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 482.0
WLSH2_k127_10074492_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 437.0
WLSH2_k127_10074492_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 417.0
WLSH2_k127_10074492_3 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 340.0
WLSH2_k127_10074492_4 Transcriptional regulator K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 302.0
WLSH2_k127_10074492_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 289.0
WLSH2_k127_10074492_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000000000273 208.0
WLSH2_k127_10074492_7 phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.0000000000000000000000000000000000004049 143.0
WLSH2_k127_10098014_0 Actin K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 574.0
WLSH2_k127_10098014_1 Cell shape-determining protein K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - 0.0000000000000000000000000000000000000000000000000000000000005477 218.0
WLSH2_k127_10123253_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 3.635e-220 700.0
WLSH2_k127_10123253_1 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 455.0
WLSH2_k127_10123253_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
WLSH2_k127_10123253_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 287.0
WLSH2_k127_10123253_4 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006729 236.0
WLSH2_k127_10123253_5 small multidrug export protein - - - 0.0000000000000000000000000000000000000000000000000003888 194.0
WLSH2_k127_10123253_6 Uncharacterized protein conserved in bacteria (DUF2322) - - - 0.0000000000000000000000000000007974 124.0
WLSH2_k127_10123253_7 Penicillin-insensitive murein endopeptidase K07261 - - 0.0000000000000005025 81.0
WLSH2_k127_10123253_8 Protein of unknown function (DUF3592) - - - 0.0001894 49.0
WLSH2_k127_10169121_0 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 579.0
WLSH2_k127_10169121_1 Dehydrogenase E1 component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 517.0
WLSH2_k127_10169121_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 357.0
WLSH2_k127_10169121_4 e3 binding domain K00382 - 1.8.1.4 0.0000000000002651 72.0
WLSH2_k127_10191445_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000004615 231.0
WLSH2_k127_10191445_1 cytochrome c - - - 0.00000006543 57.0
WLSH2_k127_10191445_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000008514 52.0
WLSH2_k127_10210860_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 331.0
WLSH2_k127_10210860_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001217 252.0
WLSH2_k127_10210860_2 transcription activator, effector binding - - - 0.000000003116 64.0
WLSH2_k127_10235647_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 477.0
WLSH2_k127_10235647_1 polysaccharide deacetylase K01452 - 3.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 336.0
WLSH2_k127_10235647_2 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 317.0
WLSH2_k127_10235647_3 esterase - - - 0.00000000000000000000000000000000000000000000000000002119 197.0
WLSH2_k127_10235647_4 MMPL family - - - 0.000002092 49.0
WLSH2_k127_10236700_0 Tex-like protein N-terminal domain protein K06959 - - 0.0 1022.0
WLSH2_k127_10236700_1 type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 294.0
WLSH2_k127_10236700_2 Flp pilus assembly protein TadB K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001838 278.0
WLSH2_k127_10236700_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000111 134.0
WLSH2_k127_10236700_4 Family of unknown function (DUF5362) - - - 0.000000000000000000000000005969 114.0
WLSH2_k127_10242647_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 634.0
WLSH2_k127_10242647_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 367.0
WLSH2_k127_10242647_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 332.0
WLSH2_k127_10244886_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 382.0
WLSH2_k127_10244886_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 303.0
WLSH2_k127_10244886_2 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000242 239.0
WLSH2_k127_10244886_3 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000005868 207.0
WLSH2_k127_10267129_0 Dynamin family - - - 5.144e-198 637.0
WLSH2_k127_10267129_1 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 566.0
WLSH2_k127_10267129_2 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 494.0
WLSH2_k127_10267129_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 331.0
WLSH2_k127_10267129_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 298.0
WLSH2_k127_10267129_5 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000005404 195.0
WLSH2_k127_10267129_6 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000000004045 124.0
WLSH2_k127_10269325_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0050896,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 460.0
WLSH2_k127_10269325_1 helix_turn_helix gluconate operon transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 360.0
WLSH2_k127_10269325_2 WLM domain K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009167 252.0
WLSH2_k127_10269325_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000001468 96.0
WLSH2_k127_10298022_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 417.0
WLSH2_k127_10298022_1 PFAM glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 332.0
WLSH2_k127_10298022_2 Aldo/keto reductase family K00064 - 1.1.1.122 0.000000000000000000000000000000000000000000002569 165.0
WLSH2_k127_10345042_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 580.0
WLSH2_k127_10345042_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007116 240.0
WLSH2_k127_10345042_2 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000000000000008626 102.0
WLSH2_k127_10345042_3 HupH hydrogenase expression protein, C-terminal conserved region - - - 0.000000000000000003776 89.0
WLSH2_k127_10345042_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000004365 66.0
WLSH2_k127_10348606_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 560.0
WLSH2_k127_10348606_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000005744 249.0
WLSH2_k127_10348606_2 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000005763 159.0
WLSH2_k127_10348606_3 COG0642 Signal transduction histidine kinase K07678 GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 0.000000000003819 71.0
WLSH2_k127_10356105_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 391.0
WLSH2_k127_10356105_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 375.0
WLSH2_k127_10356105_2 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 351.0
WLSH2_k127_10356105_3 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005609 261.0
WLSH2_k127_10356105_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000526 246.0
WLSH2_k127_10356105_5 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000001083 228.0
WLSH2_k127_10356105_6 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000001019 182.0
WLSH2_k127_10356105_7 Protein of unknown function (DUF2782) - - - 0.0000000000000000000002067 100.0
WLSH2_k127_10356105_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000001818 104.0
WLSH2_k127_10366489_0 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 477.0
WLSH2_k127_10366489_1 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 333.0
WLSH2_k127_10366489_2 SseB protein N-terminal domain - - - 0.0000000000000000000000000000000000009045 144.0
WLSH2_k127_10366489_4 beta-lactamase activity K07126 - - 0.0000344 48.0
WLSH2_k127_10386793_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000005293 186.0
WLSH2_k127_10386793_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000001648 158.0
WLSH2_k127_10386842_0 Capsule polysaccharide biosynthesis protein K07266 - - 6.016e-271 850.0
WLSH2_k127_10386842_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 587.0
WLSH2_k127_10386842_10 PFAM Integrase, catalytic core - - - 0.000000000000005612 76.0
WLSH2_k127_10386842_12 PFAM Integrase, catalytic core K07497 - - 0.0000000639 57.0
WLSH2_k127_10386842_2 epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304 520.0
WLSH2_k127_10386842_3 Capsule polysaccharide biosynthesis protein K07265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 524.0
WLSH2_k127_10386842_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 332.0
WLSH2_k127_10386842_5 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 321.0
WLSH2_k127_10386842_6 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000000000000000000000000000000000000000000000008424 220.0
WLSH2_k127_10386842_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000001457 208.0
WLSH2_k127_10386842_9 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000002618 103.0
WLSH2_k127_10388960_0 PFAM peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 4.198e-211 669.0
WLSH2_k127_10388960_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000001295 216.0
WLSH2_k127_10400243_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 453.0
WLSH2_k127_10400243_1 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 434.0
WLSH2_k127_10400243_2 ATP-dependent helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 316.0
WLSH2_k127_10412547_0 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000000008974 125.0
WLSH2_k127_10412547_1 Prepilin-type cleavage methylation-like K02672 - - 0.000000000000000000000000004124 123.0
WLSH2_k127_10412547_2 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000002805 94.0
WLSH2_k127_10412547_3 Type II transport protein GspH - - - 0.00000000000000002369 93.0
WLSH2_k127_10412547_4 Neisseria PilC beta-propeller domain K02674 - - 0.00000000005158 71.0
WLSH2_k127_10412547_5 Pilus assembly protein PilX K02673 - - 0.00001913 54.0
WLSH2_k127_10424014_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 2.381e-197 623.0
WLSH2_k127_10424014_1 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 400.0
WLSH2_k127_10424014_10 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000003875 166.0
WLSH2_k127_10424014_11 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000005017 146.0
WLSH2_k127_10424014_12 Belongs to the frataxin family K06202 - - 0.00000000000000000000000000002003 121.0
WLSH2_k127_10424014_13 - - - - 0.0000000000000000753 83.0
WLSH2_k127_10424014_2 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 386.0
WLSH2_k127_10424014_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 383.0
WLSH2_k127_10424014_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 373.0
WLSH2_k127_10424014_5 PFAM Redoxin - GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 371.0
WLSH2_k127_10424014_6 histidine kinase A domain protein K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 381.0
WLSH2_k127_10424014_7 hydrogen peroxide-inducible genes K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001152 287.0
WLSH2_k127_10424014_8 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003181 265.0
WLSH2_k127_10424014_9 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000001131 190.0
WLSH2_k127_10455423_0 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 332.0
WLSH2_k127_10455423_1 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003054 268.0
WLSH2_k127_10473236_0 Thymidine phosphorylase K00758 - 2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 438.0
WLSH2_k127_10473236_1 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003337 244.0
WLSH2_k127_10474849_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003542 294.0
WLSH2_k127_10474849_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000000000000000000000006066 216.0
WLSH2_k127_10474849_2 - - - - 0.00000000000000000000000000000009427 129.0
WLSH2_k127_10474849_3 Rhomboid family - - - 0.0000000000000000000000000000002056 130.0
WLSH2_k127_10474849_4 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000001661 108.0
WLSH2_k127_10474849_5 - - - - 0.000000000003999 79.0
WLSH2_k127_10474849_6 - - - - 0.00000008392 61.0
WLSH2_k127_10474849_7 Sel1-like repeats. - - - 0.00007403 48.0
WLSH2_k127_1050444_0 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 501.0
WLSH2_k127_1050444_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 329.0
WLSH2_k127_1050444_2 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000000000000000000000000000000038 214.0
WLSH2_k127_10520891_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1063.0
WLSH2_k127_10520891_1 phosphonoacetaldehyde hydrolase activity - - - 0.00000000000002752 74.0
WLSH2_k127_10520891_2 Aminotransferase class I and II K00013,K00817 - 1.1.1.23,2.6.1.9 0.000000001222 59.0
WLSH2_k127_10554953_0 PFAM Glu Leu Phe Val dehydrogenase K15371 - 1.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 500.0
WLSH2_k127_10554953_1 - - - - 0.0004181 48.0
WLSH2_k127_10563430_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.785e-301 938.0
WLSH2_k127_10563430_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000126 262.0
WLSH2_k127_10563430_2 PFAM YicC-like - - - 0.0000000000000000000000000000000000000000002991 161.0
WLSH2_k127_10563430_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000001043 111.0
WLSH2_k127_10578039_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 2.022e-211 689.0
WLSH2_k127_10578039_1 - - - - 0.0000000000000008973 83.0
WLSH2_k127_10578039_2 - - - - 0.000000000007069 66.0
WLSH2_k127_10593370_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.942e-224 709.0
WLSH2_k127_10616817_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 6.14e-277 857.0
WLSH2_k127_10616817_1 ATP synthase A chain K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 411.0
WLSH2_k127_10616817_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 406.0
WLSH2_k127_10616817_3 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 368.0
WLSH2_k127_10616817_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000004622 194.0
WLSH2_k127_10616817_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000004964 190.0
WLSH2_k127_10616817_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000002301 126.0
WLSH2_k127_10616817_7 ATP synthase I chain K02116 - - 0.000001114 55.0
WLSH2_k127_10659825_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 551.0
WLSH2_k127_10659825_1 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 434.0
WLSH2_k127_10659825_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 308.0
WLSH2_k127_10659825_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000007893 186.0
WLSH2_k127_10664821_0 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 380.0
WLSH2_k127_10664821_1 Na+/Pi-cotransporter K03324 - - 0.0000000000000000000000000000000000000000000000000000001343 208.0
WLSH2_k127_10664821_2 low molecular weight phosphotyrosine protein phosphatase - - - 0.0000000000000000000000000000000000000000004276 160.0
WLSH2_k127_10664821_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000005128 139.0
WLSH2_k127_10664821_4 Polyphosphate AMP phosphotransferase - - - 0.000000000000000000000000000006247 119.0
WLSH2_k127_10747495_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 608.0
WLSH2_k127_10747495_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 491.0
WLSH2_k127_10747495_2 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000001434 139.0
WLSH2_k127_10747495_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000001984 76.0
WLSH2_k127_10779840_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 545.0
WLSH2_k127_10779840_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0008652,GO:0008743,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046870,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 471.0
WLSH2_k127_10779840_2 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000001135 154.0
WLSH2_k127_10779840_3 DsrC like protein - - - 0.000000000000000000000000000003017 124.0
WLSH2_k127_10803024_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 2.048e-201 635.0
WLSH2_k127_10803024_1 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000001424 210.0
WLSH2_k127_10803024_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000003511 184.0
WLSH2_k127_10803024_3 Belongs to the UPF0149 family K09895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000005631 174.0
WLSH2_k127_10803024_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000006427 98.0
WLSH2_k127_10803024_5 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000000003898 74.0
WLSH2_k127_10828824_0 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 332.0
WLSH2_k127_10828824_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000002308 241.0
WLSH2_k127_10828824_2 PFAM Amino acid-binding ACT K03567 - - 0.00000000000000000000000000000000000000000000000000000004664 202.0
WLSH2_k127_10828824_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000002671 78.0
WLSH2_k127_10830349_0 COG0306 Phosphate sulphate permeases K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 597.0
WLSH2_k127_10830349_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 536.0
WLSH2_k127_10830349_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 344.0
WLSH2_k127_10830349_3 Bacterioferritin (cytochrome b1) K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005801 275.0
WLSH2_k127_10830349_4 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002792 256.0
WLSH2_k127_10830349_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000187 125.0
WLSH2_k127_10868629_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 524.0
WLSH2_k127_10868629_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 421.0
WLSH2_k127_10868629_10 Heavy-metal-associated domain K07213 - - 0.000000002028 63.0
WLSH2_k127_10868629_2 Branched-chain amino acid ATP-binding cassette transporter K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 369.0
WLSH2_k127_10868629_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000002495 256.0
WLSH2_k127_10868629_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008442 244.0
WLSH2_k127_10868629_5 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000000000000000000002584 194.0
WLSH2_k127_10868629_6 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000004563 175.0
WLSH2_k127_10868629_7 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000000000000000188 166.0
WLSH2_k127_10868629_8 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.0000000000000000000000009413 111.0
WLSH2_k127_10868629_9 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000001161 71.0
WLSH2_k127_10890244_0 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 368.0
WLSH2_k127_10890244_1 transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005885 321.0
WLSH2_k127_10930609_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000004654 228.0
WLSH2_k127_10930609_1 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.000000000000000000000000000000000000000000000000000501 188.0
WLSH2_k127_10930609_2 Myosin-crossreactive antigen K10254 - 4.2.1.53 0.000000000000000000000000000000000000006986 149.0
WLSH2_k127_10930609_3 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000002109 148.0
WLSH2_k127_10930609_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.00002902 53.0
WLSH2_k127_10966848_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.226e-305 956.0
WLSH2_k127_10966848_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001017 282.0
WLSH2_k127_10966848_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000008238 132.0
WLSH2_k127_10975098_0 glycosyl - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 372.0
WLSH2_k127_10975098_1 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000003305 139.0
WLSH2_k127_10975098_2 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.0000000000000009201 78.0
WLSH2_k127_10986332_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.354e-298 922.0
WLSH2_k127_10986332_1 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit K00240 GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0022904,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000004778 195.0
WLSH2_k127_11001067_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 560.0
WLSH2_k127_11001067_1 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006614 271.0
WLSH2_k127_11001067_2 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000003093 165.0
WLSH2_k127_11005944_0 PEP-utilising enzyme, TIM barrel domain K01007,K21787 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 502.0
WLSH2_k127_11005944_1 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 449.0
WLSH2_k127_11005944_2 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 426.0
WLSH2_k127_11005944_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001448 257.0
WLSH2_k127_11005944_4 Part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000005035 127.0
WLSH2_k127_11005944_5 - - - - 0.0000000000000000000000001246 111.0
WLSH2_k127_11005944_6 - - - - 0.00000000000000002447 83.0
WLSH2_k127_11044317_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 3.595e-282 874.0
WLSH2_k127_11044317_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 333.0
WLSH2_k127_11044317_2 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000004363 148.0
WLSH2_k127_11044317_3 Belongs to the ompA family K03286 - - 0.000000000000000000000000003322 124.0
WLSH2_k127_11064236_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000001449 235.0
WLSH2_k127_11064236_1 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.00000000000000000000000000000000000000000000003727 175.0
WLSH2_k127_11064236_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000001291 72.0
WLSH2_k127_11069449_0 type II restriction enzyme, methylase - - - 8.507e-254 799.0
WLSH2_k127_11069449_1 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000000000000000000001099 151.0
WLSH2_k127_11069449_2 sequence-specific DNA binding K07110 - - 0.0000000000000000000000000001674 119.0
WLSH2_k127_11072717_0 Conserved hypothetical ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000253 216.0
WLSH2_k127_11072717_1 Conserved hypothetical ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000002081 204.0
WLSH2_k127_11072717_2 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000004643 193.0
WLSH2_k127_11072717_3 - - - - 0.000000000000000002633 92.0
WLSH2_k127_11072717_4 - - - - 0.000000002228 68.0
WLSH2_k127_11091997_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 488.0
WLSH2_k127_11091997_1 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 308.0
WLSH2_k127_11091997_2 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000002154 88.0
WLSH2_k127_11104834_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1214.0
WLSH2_k127_11104834_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 477.0
WLSH2_k127_11104834_10 domain, Protein - - - 0.000000000000003491 89.0
WLSH2_k127_11104834_2 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 320.0
WLSH2_k127_11104834_3 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 310.0
WLSH2_k127_11104834_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 298.0
WLSH2_k127_11104834_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
WLSH2_k127_11104834_6 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000008106 211.0
WLSH2_k127_11104834_7 Belongs to the DsbB family K03611 - - 0.00000000000000000000000000000000000000000000000006864 181.0
WLSH2_k127_11104834_8 Phage Tail Collar Domain - - - 0.000000000000000000000000000000000000000008474 161.0
WLSH2_k127_11104834_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000214 138.0
WLSH2_k127_11206665_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 521.0
WLSH2_k127_11206665_1 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 371.0
WLSH2_k127_11206665_2 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000008446 191.0
WLSH2_k127_11206665_3 - - - - 0.00001012 54.0
WLSH2_k127_11207_0 Outer membrane protein beta-barrel family - - - 1.965e-246 775.0
WLSH2_k127_11207_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 467.0
WLSH2_k127_11207_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000008415 156.0
WLSH2_k127_11207_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0003282 49.0
WLSH2_k127_11207512_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 580.0
WLSH2_k127_11207512_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003712 233.0
WLSH2_k127_11207512_2 Predicted membrane protein (DUF2238) - - - 0.000000000000000000000000000000000000000000000000000000001062 208.0
WLSH2_k127_11207512_3 - - - - 0.0000000000000000000000000000000005435 137.0
WLSH2_k127_11207512_4 Glycine zipper - - - 0.0000000000000000000000002487 121.0
WLSH2_k127_11207512_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000001491 86.0
WLSH2_k127_1123512_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.81e-312 970.0
WLSH2_k127_1123512_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.464e-207 649.0
WLSH2_k127_1123512_2 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 298.0
WLSH2_k127_1123512_3 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000000007928 107.0
WLSH2_k127_11265131_0 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 425.0
WLSH2_k127_11265131_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 372.0
WLSH2_k127_11265131_2 response regulator receiver K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 288.0
WLSH2_k127_11265131_3 phosphoribosyltransferase K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000003562 230.0
WLSH2_k127_11265131_4 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000001564 191.0
WLSH2_k127_11265131_5 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000009582 115.0
WLSH2_k127_1135159_0 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 349.0
WLSH2_k127_1135159_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 350.0
WLSH2_k127_1135159_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000002618 224.0
WLSH2_k127_1135159_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000002948 131.0
WLSH2_k127_1135159_4 GtrA-like protein - - - 0.00000000000000000000000000001964 122.0
WLSH2_k127_11352715_0 PFAM ABC-type uncharacterised transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 451.0
WLSH2_k127_11352715_1 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008695 422.0
WLSH2_k127_11352715_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 314.0
WLSH2_k127_11352715_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 294.0
WLSH2_k127_11352715_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000006581 247.0
WLSH2_k127_11352715_5 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000003645 171.0
WLSH2_k127_1141240_0 Transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
WLSH2_k127_1141240_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000002484 186.0
WLSH2_k127_1141240_2 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000005641 123.0
WLSH2_k127_1141240_3 Protein of unknown function (DUF3579) - - - 0.00000000000002704 76.0
WLSH2_k127_1141240_4 Belongs to the sulfur carrier protein TusA family - - - 0.0001659 51.0
WLSH2_k127_11421329_0 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 391.0
WLSH2_k127_11421329_1 chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 347.0
WLSH2_k127_11421329_2 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000001335 207.0
WLSH2_k127_11421329_3 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000165 178.0
WLSH2_k127_11421329_4 FMN-binding - - - 0.00000000000000000000000000000000000000000000003498 175.0
WLSH2_k127_11421329_5 PepSY-associated TM region - - - 0.00000000000004756 81.0
WLSH2_k127_11429304_0 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 546.0
WLSH2_k127_11429304_1 Belongs to the transferase hexapeptide repeat family K00674 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.0000000000000000000000000000000000000000000002402 170.0
WLSH2_k127_11456271_0 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 466.0
WLSH2_k127_11460541_0 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 632.0
WLSH2_k127_11460541_1 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000000000000000000000518 101.0
WLSH2_k127_11491935_0 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 345.0
WLSH2_k127_11491935_1 - K07039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 318.0
WLSH2_k127_11491935_2 Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000000000000000000000000000004162 194.0
WLSH2_k127_11491935_3 WYL domain - - - 0.000000001409 60.0
WLSH2_k127_11553330_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000005916 232.0
WLSH2_k127_11553330_1 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000001443 216.0
WLSH2_k127_11553330_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000001093 188.0
WLSH2_k127_11563194_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 381.0
WLSH2_k127_11563194_1 Pfam Hemerythrin HHE - - - 0.00000000000000000000000000000000000000000000003218 175.0
WLSH2_k127_11563194_2 LTXXQ motif family protein - - - 0.0000000000000008657 86.0
WLSH2_k127_11563194_3 Uncharacterized conserved protein (DUF2249) - - - 0.0000001197 55.0
WLSH2_k127_11563194_4 Domain of unknown function DUF302 - - - 0.0000007245 51.0
WLSH2_k127_11571080_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 375.0
WLSH2_k127_11571080_1 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
WLSH2_k127_11571080_2 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000231 281.0
WLSH2_k127_11571080_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002563 272.0
WLSH2_k127_11571080_4 helix_turn_helix, Lux Regulon K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003136 267.0
WLSH2_k127_1164476_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 513.0
WLSH2_k127_1164476_1 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 491.0
WLSH2_k127_1164476_2 PFAM ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 474.0
WLSH2_k127_1164476_3 Xylose isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 404.0
WLSH2_k127_1164476_4 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 383.0
WLSH2_k127_1164476_5 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 338.0
WLSH2_k127_1164476_6 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002898 258.0
WLSH2_k127_1164476_7 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000006317 146.0
WLSH2_k127_1176660_0 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K07006,K21832 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 582.0
WLSH2_k127_1176660_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 312.0
WLSH2_k127_1176660_2 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008576 240.0
WLSH2_k127_1176660_3 Class III cytochrome C family - - - 0.0000000817 54.0
WLSH2_k127_1182657_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 401.0
WLSH2_k127_1182657_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000001882 243.0
WLSH2_k127_1182657_2 protein conserved in bacteria K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000006176 163.0
WLSH2_k127_1182657_3 Sterol-binding domain protein K03690 - - 0.0000000000000000000000000000000000000000001877 166.0
WLSH2_k127_1182657_4 membrane protein domain - - - 0.0000000000000000000000000000001377 130.0
WLSH2_k127_1190266_0 Phage tail sheath protein K06907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 464.0
WLSH2_k127_1190266_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000001415 194.0
WLSH2_k127_1190266_3 PFAM Phage tail sheath protein K06907 - - 0.0000000000000000000000000000001963 124.0
WLSH2_k127_1190266_4 Transposase - - - 0.0001545 47.0
WLSH2_k127_1192086_0 reductase K00021 - 1.1.1.34 0.000000000000000000000000000000000000000000000001431 180.0
WLSH2_k127_1192086_1 - - - - 0.0000000000000000001274 95.0
WLSH2_k127_1194152_0 - - - - 0.000000000000000000000000000000000000000005219 160.0
WLSH2_k127_1194152_1 - - - - 0.0000000000000000000000000000000000000003679 160.0
WLSH2_k127_1194152_2 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000002257 135.0
WLSH2_k127_1194152_3 - - - - 0.00000000000000000000000001012 124.0
WLSH2_k127_1194152_4 COG3039 Transposase and inactivated derivatives, IS5 family K07481 - - 0.00001221 48.0
WLSH2_k127_1194152_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase - - - 0.00007344 45.0
WLSH2_k127_1198347_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1331.0
WLSH2_k127_1198347_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 5.092e-242 759.0
WLSH2_k127_1198347_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000004311 197.0
WLSH2_k127_1198347_11 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000002161 143.0
WLSH2_k127_1198347_12 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000000000001529 89.0
WLSH2_k127_1198347_13 Protein of unknown function (DUF721) - - - 0.00000001689 62.0
WLSH2_k127_1198347_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 508.0
WLSH2_k127_1198347_3 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 508.0
WLSH2_k127_1198347_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 467.0
WLSH2_k127_1198347_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 415.0
WLSH2_k127_1198347_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 369.0
WLSH2_k127_1198347_7 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 320.0
WLSH2_k127_1198347_8 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 310.0
WLSH2_k127_1198347_9 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 287.0
WLSH2_k127_1225012_0 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 601.0
WLSH2_k127_1225012_1 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 304.0
WLSH2_k127_1225012_2 Peptidase m48 ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000007987 244.0
WLSH2_k127_1225012_3 Sh3 type 3 domain protein K02450,K12132 - 2.7.11.1 0.000000000000000000007952 100.0
WLSH2_k127_1226567_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 7e-323 1002.0
WLSH2_k127_1226567_1 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 610.0
WLSH2_k127_1226567_2 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 595.0
WLSH2_k127_1226567_3 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 449.0
WLSH2_k127_1226567_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 423.0
WLSH2_k127_1226567_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 322.0
WLSH2_k127_1226567_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001537 287.0
WLSH2_k127_1226567_7 Uncharacterised protein family UPF0066 - GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000001897 159.0
WLSH2_k127_1226823_0 Domain of unknown function (DUF3400) - - - 2.244e-300 931.0
WLSH2_k127_1236642_0 amine dehydrogenase activity - - - 0.0000000000000000000246 104.0
WLSH2_k127_1236642_1 Phage integrase family - - - 0.00000000000000000004171 93.0
WLSH2_k127_1236797_0 HypF finger - - - 5.869e-248 792.0
WLSH2_k127_1236797_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 426.0
WLSH2_k127_1236797_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 403.0
WLSH2_k127_1236797_3 Belongs to the thioredoxin family K05838 - - 0.000000000000000000000000000000001653 130.0
WLSH2_k127_1263426_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 552.0
WLSH2_k127_1263426_1 Belongs to the SfsA family K06206 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000001705 249.0
WLSH2_k127_1263426_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000008061 157.0
WLSH2_k127_1263426_3 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000001323 156.0
WLSH2_k127_1263471_0 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 406.0
WLSH2_k127_1263471_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 304.0
WLSH2_k127_1265379_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 436.0
WLSH2_k127_1265379_1 COG0842 ABC-type multidrug transport system, permease component K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 360.0
WLSH2_k127_1265379_2 Peptidase, M16 K06972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 318.0
WLSH2_k127_1265379_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000003875 173.0
WLSH2_k127_1272211_0 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000009241 231.0
WLSH2_k127_1272211_1 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000000000000000000000669 167.0
WLSH2_k127_1272211_2 General secretion pathway protein K02455 - - 0.00000000000000000000000000305 111.0
WLSH2_k127_1272211_3 Type II secretion system (T2SS), protein I - - - 0.0000000000000000003293 92.0
WLSH2_k127_1272211_4 general secretion pathway protein H K02457 - - 0.0000000000000001891 91.0
WLSH2_k127_1272211_5 Type II secretion system (T2SS), protein K K02460 - - 0.0002229 48.0
WLSH2_k127_1308619_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.885e-271 845.0
WLSH2_k127_1308619_1 COG1522 Transcriptional regulators K03719 - - 0.0000000000000000000001017 98.0
WLSH2_k127_133806_0 Citrate transporter - - - 2.409e-229 728.0
WLSH2_k127_1367025_0 Belongs to the dihydroorotate dehydrogenase family K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 528.0
WLSH2_k127_1367025_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.000000000000000000000000000000000000000000000000000000003679 201.0
WLSH2_k127_1371918_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000036 256.0
WLSH2_k127_1371918_1 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000006259 222.0
WLSH2_k127_1371918_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000001789 179.0
WLSH2_k127_1371918_3 PFAM VanZ - - - 0.000000000000000001471 90.0
WLSH2_k127_1371918_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000339 65.0
WLSH2_k127_1381857_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 381.0
WLSH2_k127_1381857_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004638 273.0
WLSH2_k127_1381857_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001223 237.0
WLSH2_k127_1381857_3 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000000000000000000007917 186.0
WLSH2_k127_1381857_4 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.000000000000000000000000000000000000000000000012 177.0
WLSH2_k127_1381857_5 - - - - 0.00000000000000000000000000006374 120.0
WLSH2_k127_1381857_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000003496 122.0
WLSH2_k127_1385281_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 351.0
WLSH2_k127_1385281_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000003695 127.0
WLSH2_k127_1386002_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.492e-318 985.0
WLSH2_k127_1386002_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 513.0
WLSH2_k127_1386002_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000001078 226.0
WLSH2_k127_1386002_3 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000003908 223.0
WLSH2_k127_1386002_4 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000000009835 140.0
WLSH2_k127_1386002_5 - - - - 0.000000000000000000000006108 106.0
WLSH2_k127_1386002_6 carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000003489 82.0
WLSH2_k127_1388355_0 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000752 224.0
WLSH2_k127_1388355_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000008063 215.0
WLSH2_k127_1388355_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051234,GO:0051641,GO:0055085,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0097159,GO:0097367,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1990778 - 0.0000000000000000104 83.0
WLSH2_k127_1429819_0 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 337.0
WLSH2_k127_1429819_1 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004262 286.0
WLSH2_k127_1429819_2 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000009377 224.0
WLSH2_k127_1429819_3 self proteolysis - - - 0.00000000000000000000000000000000000000000000000000001651 194.0
WLSH2_k127_1429819_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000009481 190.0
WLSH2_k127_1429819_5 - - - - 0.0000000000000000000002663 101.0
WLSH2_k127_1429819_6 SMART Elongator protein 3 MiaB NifB - - - 0.00002287 46.0
WLSH2_k127_1431470_0 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 397.0
WLSH2_k127_1431470_1 TIGRFAM ABC-2 type transporter, NodJ K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003198 278.0
WLSH2_k127_1431470_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000001508 235.0
WLSH2_k127_1431470_3 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000168 228.0
WLSH2_k127_1431470_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000007844 186.0
WLSH2_k127_1431470_5 Ferredoxin - - - 0.00000000000000000000000000000000000000000001195 164.0
WLSH2_k127_1431470_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000005289 143.0
WLSH2_k127_1450_0 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 516.0
WLSH2_k127_1450_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 370.0
WLSH2_k127_1450_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 360.0
WLSH2_k127_1450_3 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 353.0
WLSH2_k127_1450_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001148 276.0
WLSH2_k127_1450_5 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000004027 166.0
WLSH2_k127_1478471_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.616e-316 985.0
WLSH2_k127_1478471_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000003787 112.0
WLSH2_k127_1478471_2 - - - - 0.0000000000000000001933 90.0
WLSH2_k127_1478471_3 domain, Protein K03112 - - 0.0000002216 63.0
WLSH2_k127_1488567_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 1.492e-276 862.0
WLSH2_k127_1488567_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 467.0
WLSH2_k127_1488567_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000227 256.0
WLSH2_k127_1488567_3 ferredoxin, 2Fe-2S K04755 - - 0.00000000000000000000000000000000000000000000000000000000003413 207.0
WLSH2_k127_1488567_4 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000003647 206.0
WLSH2_k127_1488567_5 Iron-sulphur cluster assembly - - - 0.0000000000000000000000004971 105.0
WLSH2_k127_1488567_6 Domain of unknown function (DUF4115) K15539 - - 0.00000000000004167 81.0
WLSH2_k127_1501812_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003254 269.0
WLSH2_k127_150707_0 GGDEF domain - - - 0.0000000000000000000000000000000000000000001654 177.0
WLSH2_k127_150707_1 CoA-substrate-specific enzyme activase - - - 0.000000000000000000000000000000000000006986 149.0
WLSH2_k127_150707_2 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000003089 96.0
WLSH2_k127_1554217_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 0.0 1008.0
WLSH2_k127_1554217_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000001131 91.0
WLSH2_k127_1575860_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000008475 262.0
WLSH2_k127_1575860_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000003882 259.0
WLSH2_k127_1575860_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000003384 235.0
WLSH2_k127_1575860_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000006589 151.0
WLSH2_k127_1575860_4 - - - - 0.00000000008397 64.0
WLSH2_k127_1577682_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.117e-212 668.0
WLSH2_k127_1577682_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 421.0
WLSH2_k127_1577682_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000002326 204.0
WLSH2_k127_1577682_3 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000003576 164.0
WLSH2_k127_1577682_4 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000006231 74.0
WLSH2_k127_1577682_5 carboxylic ester hydrolase activity - - - 0.000000145 54.0
WLSH2_k127_158024_0 Heat shock 70 kDa protein K04043 - - 1.525e-286 891.0
WLSH2_k127_158024_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 5.384e-265 830.0
WLSH2_k127_1599328_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 378.0
WLSH2_k127_1599328_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000002386 217.0
WLSH2_k127_1599328_2 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000001683 176.0
WLSH2_k127_1599328_3 PFAM Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000007089 84.0
WLSH2_k127_1604087_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 516.0
WLSH2_k127_1604087_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000001724 74.0
WLSH2_k127_1604087_2 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.00000000001059 70.0
WLSH2_k127_1604087_3 Transposase IS200 like K07491 - - 0.0001668 44.0
WLSH2_k127_1611472_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 611.0
WLSH2_k127_1611472_1 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 347.0
WLSH2_k127_1611472_2 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 292.0
WLSH2_k127_1611472_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003003 244.0
WLSH2_k127_1611472_4 membrane - - - 0.0000000000000000000000000000000000002568 144.0
WLSH2_k127_1611472_5 - - - - 0.000000000000000000000000000000002056 137.0
WLSH2_k127_1611472_6 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000001053 121.0
WLSH2_k127_1611472_7 small protein containing a coiled-coil domain - - - 0.000000000000000001408 87.0
WLSH2_k127_1611472_8 Belongs to the globin family K05916 - 1.14.12.17 0.00000000000000006726 91.0
WLSH2_k127_1611472_9 Protozoan cyanobacterial globin family protein - - - 0.000005731 57.0
WLSH2_k127_1614776_0 diguanylate cyclase activity K13069 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 431.0
WLSH2_k127_1614776_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 377.0
WLSH2_k127_1614776_2 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000000000003865 159.0
WLSH2_k127_1614776_3 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000009745 155.0
WLSH2_k127_1614776_4 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000002895 96.0
WLSH2_k127_1614776_5 CYTH - - - 0.00000000003466 71.0
WLSH2_k127_1709046_0 peptidase K01414 - 3.4.24.70 9.916e-310 962.0
WLSH2_k127_1709046_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 1.19e-199 633.0
WLSH2_k127_1709046_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 411.0
WLSH2_k127_1709046_3 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000008083 207.0
WLSH2_k127_1709046_4 - - - - 0.00000000000000000000000000000000000000000000000000000000937 207.0
WLSH2_k127_1709046_5 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000001987 192.0
WLSH2_k127_1709046_6 - - - - 0.000000000000007962 79.0
WLSH2_k127_171031_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 516.0
WLSH2_k127_171031_1 COG0331 (acyl-carrier-protein) S-malonyltransferase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 395.0
WLSH2_k127_171031_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 366.0
WLSH2_k127_171031_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000001874 136.0
WLSH2_k127_1721640_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 392.0
WLSH2_k127_1721640_1 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000000002178 169.0
WLSH2_k127_1721640_2 PFAM SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000003611 169.0
WLSH2_k127_1736910_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.654e-214 680.0
WLSH2_k127_1736910_1 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000005264 183.0
WLSH2_k127_1736910_2 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000000007076 168.0
WLSH2_k127_1742229_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 565.0
WLSH2_k127_1765357_0 Domain of unknown function (DUF3400) - - - 3.445e-221 691.0
WLSH2_k127_1765357_1 L-threonine ammonia-lyase activity K01754 GO:0003674,GO:0003824,GO:0004794,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006549,GO:0006566,GO:0006567,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009081,GO:0009082,GO:0009097,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 578.0
WLSH2_k127_1765357_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0042802,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 325.0
WLSH2_k127_1765357_3 - - - - 0.00000000000000000000003739 100.0
WLSH2_k127_1827413_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 377.0
WLSH2_k127_1827413_1 Anthranilate synthase component I domain protein K01665,K13950 - 2.6.1.85 0.0000000000000000832 83.0
WLSH2_k127_1835647_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 541.0
WLSH2_k127_1835647_1 Cytochrome c K02305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002544 249.0
WLSH2_k127_1835647_2 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001253 246.0
WLSH2_k127_1835647_3 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000495 142.0
WLSH2_k127_1835647_4 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000001347 126.0
WLSH2_k127_1835647_5 Tetratricopeptide repeat - - - 0.000000000000000000002911 108.0
WLSH2_k127_1835647_6 COG0457 FOG TPR repeat - - - 0.0000000000000000004728 95.0
WLSH2_k127_1835647_7 Nitric oxide reductase K04561 - 1.7.2.5 0.0000001802 53.0
WLSH2_k127_1835647_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000004489 54.0
WLSH2_k127_1836663_0 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 6.505e-234 726.0
WLSH2_k127_1836663_1 Diguanylate cyclase - - - 1.95e-197 647.0
WLSH2_k127_1836663_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000003715 224.0
WLSH2_k127_1873057_0 AMP-binding enzyme C-terminal domain K00666 - - 3.142e-226 708.0
WLSH2_k127_1905856_0 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000000000000008814 143.0
WLSH2_k127_1905856_1 - - - - 0.00000000000000179 76.0
WLSH2_k127_1905856_2 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000001022 73.0
WLSH2_k127_1923868_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 444.0
WLSH2_k127_1923868_1 Macrophage migration inhibitory factor (MIF) - - - 0.000000000000000000000000006687 116.0
WLSH2_k127_1923868_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000003167 89.0
WLSH2_k127_1923868_3 Domain of unknown function (DUF4124) - - - 0.0000002848 59.0
WLSH2_k127_1948560_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 623.0
WLSH2_k127_1948560_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 496.0
WLSH2_k127_1948560_2 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 377.0
WLSH2_k127_1948560_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 332.0
WLSH2_k127_1948560_4 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
WLSH2_k127_1948560_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000007047 247.0
WLSH2_k127_1948560_6 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.0000000000000000000000000000000000000000000000009486 185.0
WLSH2_k127_1948560_7 - - - - 0.0000000000000000000000000000504 128.0
WLSH2_k127_1948560_8 - - - - 0.00000000000000000025 96.0
WLSH2_k127_2044813_0 Respiratory nitrate reductase alpha N-terminal K00370 - 1.7.5.1 0.0 2210.0
WLSH2_k127_2044813_1 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 2.485e-286 885.0
WLSH2_k127_2044813_2 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 559.0
WLSH2_k127_2044813_3 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 312.0
WLSH2_k127_2044813_4 Nitrate reductase delta subunit K00373 - - 0.000000000000000000000000000000000000000000000000000000000000006456 225.0
WLSH2_k127_2044813_5 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.000000000000000000000000000000000000000000000000005882 183.0
WLSH2_k127_2088894_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.592e-311 966.0
WLSH2_k127_2088894_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000001115 169.0
WLSH2_k127_2088894_2 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000003028 130.0
WLSH2_k127_2088894_3 redox protein regulator of disulfide bond formation - - - 0.00000000002605 66.0
WLSH2_k127_2146579_0 Belongs to the 5'-nucleotidase family K17224 - - 8.438e-296 915.0
WLSH2_k127_2146579_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 503.0
WLSH2_k127_2146579_2 Double sensory domain of two-component sensor kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 367.0
WLSH2_k127_2146579_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 352.0
WLSH2_k127_2146579_4 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001179 274.0
WLSH2_k127_2146579_5 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001517 259.0
WLSH2_k127_2146579_6 PFAM Pentapeptide - - - 0.00000000000000000000000000000000000002896 155.0
WLSH2_k127_2146579_7 YcgL domain-containing protein K09902 - - 0.00000000000000001799 86.0
WLSH2_k127_2146579_8 Domain of unknown function (DUF3362) - - - 0.00000000318 58.0
WLSH2_k127_2146579_9 oxidoreductase activity, acting on diphenols and related substances as donors K00411 - 1.10.2.2 0.000455 49.0
WLSH2_k127_2165949_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 304.0
WLSH2_k127_2165949_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 297.0
WLSH2_k127_2172652_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 2.901e-232 726.0
WLSH2_k127_2172652_1 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 327.0
WLSH2_k127_2172652_2 ATP-dependent helicase K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 255.0
WLSH2_k127_2172652_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000002212 156.0
WLSH2_k127_2172652_4 Protein required for attachment to host cells - - - 0.000000000000000001291 95.0
WLSH2_k127_2180856_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.676e-194 614.0
WLSH2_k127_2180856_1 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 454.0
WLSH2_k127_2180856_2 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 431.0
WLSH2_k127_2180856_3 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 324.0
WLSH2_k127_2214581_0 TIGRFAM ribonuclease, Rne Rng family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 572.0
WLSH2_k127_2214581_1 Protein of unknown function - - - 0.00000000000001399 79.0
WLSH2_k127_2226446_0 Diguanylate cyclase - - - 4.463e-211 688.0
WLSH2_k127_2226446_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
WLSH2_k127_2226446_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000002074 173.0
WLSH2_k127_2226446_3 Psort location Cytoplasmic, score - - - 0.00005598 54.0
WLSH2_k127_2227298_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001392 253.0
WLSH2_k127_2227298_1 membrane-anchored protein conserved in bacteria - - - 0.0000000000209 65.0
WLSH2_k127_2228534_0 exporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 522.0
WLSH2_k127_2228534_1 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 376.0
WLSH2_k127_2228534_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000001187 215.0
WLSH2_k127_2228534_3 FabA-like domain - - - 0.0000000000000152 75.0
WLSH2_k127_2250247_0 ABC transporter - - - 1.456e-306 952.0
WLSH2_k127_2250247_1 AAA domain - - - 2.263e-287 905.0
WLSH2_k127_2250247_10 Bacterial membrane protein, YfhO - - - 0.0001616 46.0
WLSH2_k127_2250247_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 579.0
WLSH2_k127_2250247_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000002292 257.0
WLSH2_k127_2250247_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000005755 202.0
WLSH2_k127_2250247_5 - - - - 0.00000000000000000351 97.0
WLSH2_k127_2250247_6 Diguanylate cyclase - - - 0.00000000000000001272 95.0
WLSH2_k127_2250247_7 Bacterial membrane protein, YfhO - - - 0.000000000000001993 90.0
WLSH2_k127_2250247_8 response to stress - - - 0.0000002464 62.0
WLSH2_k127_2250247_9 Bacterial membrane protein YfhO - - - 0.0000003744 57.0
WLSH2_k127_2291746_0 fad dependent oxidoreductase K07137 - - 9.985e-270 840.0
WLSH2_k127_2291746_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006672 279.0
WLSH2_k127_2291746_2 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000002129 217.0
WLSH2_k127_2347070_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 376.0
WLSH2_k127_2347070_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 361.0
WLSH2_k127_2347070_2 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000001567 192.0
WLSH2_k127_237821_0 COG4972 Tfp pilus assembly protein, ATPase PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 328.0
WLSH2_k127_237821_1 Pilus assembly protein PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
WLSH2_k127_237821_2 PFAM Fimbrial assembly K02663 - - 0.0000000000000000000000000000000000000000000000000001092 191.0
WLSH2_k127_237821_3 COG4796 Type II secretory pathway, component HofQ K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000002934 173.0
WLSH2_k127_237821_4 pilus assembly protein pilp K02665 - - 0.00000000000000000000000000000000001858 141.0
WLSH2_k127_2386680_0 membrane-anchored protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001402 244.0
WLSH2_k127_2386680_1 - - - - 0.000000000000000000000000000000002617 140.0
WLSH2_k127_2386680_2 DnaJ molecular chaperone homology domain - - - 0.0000000000004695 74.0
WLSH2_k127_2401257_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.55e-208 653.0
WLSH2_k127_2401257_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 402.0
WLSH2_k127_2401257_2 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 304.0
WLSH2_k127_2441128_0 membrane K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 453.0
WLSH2_k127_2441128_1 Kef-type K transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 417.0
WLSH2_k127_2441128_2 PFAM Na Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000007694 239.0
WLSH2_k127_2441128_3 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.00000000000000000000000000000000000001106 151.0
WLSH2_k127_2441128_4 Transglutaminase-like superfamily - - - 0.0000000000000002125 89.0
WLSH2_k127_2441383_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.488e-202 638.0
WLSH2_k127_2441383_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 474.0
WLSH2_k127_2441383_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K01817 - 5.3.1.16,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000008803 229.0
WLSH2_k127_2441801_0 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 378.0
WLSH2_k127_2441801_1 PFAM DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 332.0
WLSH2_k127_2441801_2 Belongs to the Smg family K03747 - - 0.0005081 44.0
WLSH2_k127_2473082_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 2.01e-209 659.0
WLSH2_k127_2473082_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 2.877e-204 644.0
WLSH2_k127_2473082_10 Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003806 270.0
WLSH2_k127_2473082_11 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000002502 207.0
WLSH2_k127_2473082_12 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000414 198.0
WLSH2_k127_2473082_13 NUDIX domain K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000000001108 169.0
WLSH2_k127_2473082_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000007721 145.0
WLSH2_k127_2473082_15 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000003012 132.0
WLSH2_k127_2473082_16 (FHA) domain - - - 0.0000000000000000000000000000001001 132.0
WLSH2_k127_2473082_17 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.00000000000000000000004613 107.0
WLSH2_k127_2473082_2 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 515.0
WLSH2_k127_2473082_3 Phage integrase, N-terminal SAM-like domain K04763 GO:0000150,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009314,GO:0009628,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0071139,GO:0071704,GO:0090304,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 398.0
WLSH2_k127_2473082_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 382.0
WLSH2_k127_2473082_5 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 359.0
WLSH2_k127_2473082_6 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 318.0
WLSH2_k127_2473082_8 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 295.0
WLSH2_k127_2473082_9 cAMP phosphodiesterases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000317 274.0
WLSH2_k127_2473734_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 387.0
WLSH2_k127_2473734_1 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000006644 143.0
WLSH2_k127_2473734_2 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000007016 105.0
WLSH2_k127_2485873_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 0.0 1106.0
WLSH2_k127_2485873_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.279e-247 767.0
WLSH2_k127_2485873_2 response regulator receiver K02487,K06596 - - 5.617e-209 676.0
WLSH2_k127_2485873_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 4.295e-201 628.0
WLSH2_k127_2485873_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.309e-197 620.0
WLSH2_k127_2485873_5 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 401.0
WLSH2_k127_2485873_6 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 403.0
WLSH2_k127_2485873_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000001522 258.0
WLSH2_k127_2485873_8 Cytochrome - - - 0.000000000000000000000000000000000000000005838 162.0
WLSH2_k127_2485873_9 CheW-like domain K06598 - - 0.000000000000007458 81.0
WLSH2_k127_2552878_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 411.0
WLSH2_k127_2552878_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 350.0
WLSH2_k127_2552878_2 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 317.0
WLSH2_k127_2552878_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001364 269.0
WLSH2_k127_2563709_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 580.0
WLSH2_k127_2563709_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008883,GO:0009058,GO:0009064,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 541.0
WLSH2_k127_2563709_10 cytochrome - - - 0.0000000000000000000000000000000000000001318 154.0
WLSH2_k127_2563709_11 NosL - - - 0.0000000000000000000000000000000003446 136.0
WLSH2_k127_2563709_12 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000003174 94.0
WLSH2_k127_2563709_13 - - - - 0.000000000000009713 76.0
WLSH2_k127_2563709_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 535.0
WLSH2_k127_2563709_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 497.0
WLSH2_k127_2563709_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 393.0
WLSH2_k127_2563709_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 315.0
WLSH2_k127_2563709_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 295.0
WLSH2_k127_2563709_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
WLSH2_k127_2563709_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000002536 246.0
WLSH2_k127_2563709_9 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000005378 169.0
WLSH2_k127_2586689_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.749e-287 888.0
WLSH2_k127_2586689_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.412e-204 644.0
WLSH2_k127_2586689_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 468.0
WLSH2_k127_2586689_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 309.0
WLSH2_k127_2586689_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002699 261.0
WLSH2_k127_2586689_5 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000001199 244.0
WLSH2_k127_2586689_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000006119 104.0
WLSH2_k127_2586689_7 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000003519 97.0
WLSH2_k127_2701094_0 GGDEF domain containing protein - - - 4.266e-248 797.0
WLSH2_k127_2701094_1 CoA-binding domain protein K09181 - - 4.224e-244 765.0
WLSH2_k127_270552_0 Histidine kinase K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001174 277.0
WLSH2_k127_270552_1 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.00000000000000000000000000000000000000000000000006233 180.0
WLSH2_k127_270552_2 Protein of unknown function (DUF2953) - - - 0.00000000000000000000000000000000000000001524 160.0
WLSH2_k127_270552_3 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 GO:0001887,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016785,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043828,GO:0044237,GO:0044238,GO:0046483,GO:0070329,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000021 148.0
WLSH2_k127_2710247_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 1.779e-198 634.0
WLSH2_k127_2710247_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 345.0
WLSH2_k127_2710247_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008690,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 329.0
WLSH2_k127_2710247_3 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 282.0
WLSH2_k127_2710247_4 Competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001585 282.0
WLSH2_k127_2710247_5 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000003043 237.0
WLSH2_k127_2710247_6 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000004856 144.0
WLSH2_k127_2710247_7 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000009519 135.0
WLSH2_k127_2710247_8 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000309 94.0
WLSH2_k127_2712402_0 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 447.0
WLSH2_k127_2712402_1 Belongs to the GARS family K01945,K13713 GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000005249 146.0
WLSH2_k127_2712402_2 Protein of unknown function (DUF3617) - - - 0.000000001173 66.0
WLSH2_k127_2723016_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 471.0
WLSH2_k127_2725559_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 552.0
WLSH2_k127_2731094_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 413.0
WLSH2_k127_2731094_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000008897 140.0
WLSH2_k127_2743301_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 486.0
WLSH2_k127_2743301_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 400.0
WLSH2_k127_2743301_2 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 394.0
WLSH2_k127_2743301_3 - - - - 0.00000000000000000000000000000000003847 141.0
WLSH2_k127_2743301_5 Hint domain - - - 0.0000000009068 67.0
WLSH2_k127_2746566_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 509.0
WLSH2_k127_2746566_1 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 295.0
WLSH2_k127_2746566_2 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000002529 89.0
WLSH2_k127_2755705_0 membrane-bound metal-dependent K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 302.0
WLSH2_k127_2755705_1 Diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000002195 223.0
WLSH2_k127_2755705_2 Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity K13771 - - 0.000000000000000000000000000000000000000000000004523 176.0
WLSH2_k127_2760986_0 PFAM Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005398 271.0
WLSH2_k127_2760986_1 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000001787 115.0
WLSH2_k127_2788708_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 367.0
WLSH2_k127_2788708_1 HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000003426 236.0
WLSH2_k127_2802820_0 Stress responsive A/B Barrel Domain K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 360.0
WLSH2_k127_2802820_1 - - - - 0.000000000000000000000000000000000000000001914 157.0
WLSH2_k127_2802820_2 - - - - 0.0000000000000000000000000001554 123.0
WLSH2_k127_2802820_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.000000000000000000000004482 101.0
WLSH2_k127_2802820_4 Tfp pilus assembly protein FimV - - - 0.00000000000007366 85.0
WLSH2_k127_2802820_5 Von willebrand factor, type a - - - 0.0000000000154 64.0
WLSH2_k127_2815775_0 von willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 589.0
WLSH2_k127_2815775_2 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001655 199.0
WLSH2_k127_2815775_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000002249 145.0
WLSH2_k127_281647_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 287.0
WLSH2_k127_281647_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002118 280.0
WLSH2_k127_281647_2 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000642 179.0
WLSH2_k127_281647_3 metal cluster binding - - - 0.00000000000000000000000000003805 126.0
WLSH2_k127_2876966_0 Ferrous iron transport protein B K04759 - - 7.454e-243 763.0
WLSH2_k127_2876966_1 MscS Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 525.0
WLSH2_k127_2876966_2 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000001517 122.0
WLSH2_k127_2876966_3 FeoA K04758 - - 0.00000000000009435 75.0
WLSH2_k127_2878973_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.506e-295 915.0
WLSH2_k127_2878973_1 DNA polymerase III K02342 - 2.7.7.7 0.00000000000001689 74.0
WLSH2_k127_2933254_0 Peptidase U32 K08303 - - 2.402e-220 694.0
WLSH2_k127_2933254_1 Protein of unknown function (DUF938) - - - 0.0000000000000000001002 94.0
WLSH2_k127_2945466_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 432.0
WLSH2_k127_2945466_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 419.0
WLSH2_k127_2945466_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 353.0
WLSH2_k127_2945466_3 UPF0114 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
WLSH2_k127_2945466_4 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000008889 100.0
WLSH2_k127_2963190_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1503.0
WLSH2_k127_2963190_1 alpha beta alpha domain I K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 549.0
WLSH2_k127_2963190_2 PFAM Rhodanese-like - - - 0.0000000000000000000000000000000000000000000000000000000000009827 213.0
WLSH2_k127_2963190_3 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000009226 176.0
WLSH2_k127_2963190_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000009485 161.0
WLSH2_k127_2963190_5 Peptidase S24-like - - - 0.000000000000000000000000000001512 126.0
WLSH2_k127_2963190_6 PFAM Transposase IS3 IS911 - - - 0.0000000000005744 72.0
WLSH2_k127_2964575_0 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 407.0
WLSH2_k127_2964575_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 380.0
WLSH2_k127_2964575_2 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 334.0
WLSH2_k127_2964575_3 PFAM Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000004996 226.0
WLSH2_k127_2964575_4 PFAM L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000002069 217.0
WLSH2_k127_2964575_5 Cupin - - - 0.0000000000000000000000000000000000000007054 160.0
WLSH2_k127_2964575_6 - - - - 0.000000000000000000000000002584 126.0
WLSH2_k127_29835_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 3.476e-198 627.0
WLSH2_k127_29835_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 289.0
WLSH2_k127_29835_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000803 226.0
WLSH2_k127_29835_3 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
WLSH2_k127_29835_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000001616 215.0
WLSH2_k127_29835_5 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000002486 202.0
WLSH2_k127_29835_6 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000000000000000000000000008065 172.0
WLSH2_k127_29835_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000002868 164.0
WLSH2_k127_29835_8 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000000002299 143.0
WLSH2_k127_29835_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000003512 100.0
WLSH2_k127_2983804_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 461.0
WLSH2_k127_2983804_1 phosphatidylinositol transporter activity - - - 0.000000000002146 78.0
WLSH2_k127_2983804_2 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 0.00000000006159 62.0
WLSH2_k127_2983804_3 - - - - 0.000000926 60.0
WLSH2_k127_2986113_0 Cation transport ATPase (P-type) - - - 0.0 1146.0
WLSH2_k127_2986113_1 penicillin-binding protein 1C K05367 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031406,GO:0033218,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051302,GO:0051781,GO:0065007,GO:0097159,GO:1901363,GO:1901681 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004179 269.0
WLSH2_k127_2996754_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 473.0
WLSH2_k127_2996754_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 456.0
WLSH2_k127_2996754_2 response regulator receiver K02657 - - 0.00000000000000003708 81.0
WLSH2_k127_3010681_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 468.0
WLSH2_k127_3010681_1 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 396.0
WLSH2_k127_3015927_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1059.0
WLSH2_k127_3015927_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 511.0
WLSH2_k127_3015927_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.00000000000000000000000000000000000000000000000000000000000000000000000003542 252.0
WLSH2_k127_3015927_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000002579 186.0
WLSH2_k127_3015927_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000222 154.0
WLSH2_k127_3015927_5 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000666 87.0
WLSH2_k127_3015927_6 B3/4 domain K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000003174 66.0
WLSH2_k127_3017022_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 420.0
WLSH2_k127_3017022_1 RNA polymerase K03089 GO:0000150,GO:0000976,GO:0000984,GO:0000985,GO:0000988,GO:0000990,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006310,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009009,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031421,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 382.0
WLSH2_k127_3017022_2 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 316.0
WLSH2_k127_3024949_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 619.0
WLSH2_k127_3024949_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 451.0
WLSH2_k127_3024949_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 316.0
WLSH2_k127_3024949_3 ROK family - - - 0.0000000000000000000000000000000001056 133.0
WLSH2_k127_3024949_4 ThiS family K03154 - - 0.000000000000000002093 86.0
WLSH2_k127_3024949_5 - - - - 0.000000000000000004823 95.0
WLSH2_k127_3062286_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.676e-197 619.0
WLSH2_k127_3062286_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 498.0
WLSH2_k127_3062286_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000003421 203.0
WLSH2_k127_3062286_3 fatty acid desaturase - - - 0.000000000000000000000000000000003862 135.0
WLSH2_k127_3065236_0 Flavin-binding monooxygenase-like K14520 - 1.14.13.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 454.0
WLSH2_k127_3065236_1 PRMT5 oligomerisation domain K11434 - 2.1.1.319 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001956 274.0
WLSH2_k127_3072565_0 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis K20327 - - 2.149e-244 769.0
WLSH2_k127_3072565_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 383.0
WLSH2_k127_3072565_10 PFAM Beta-propeller repeat - - - 0.00000000000000000000007116 110.0
WLSH2_k127_3072565_11 PFAM ResB family protein K07399 - - 0.000000000000000004608 87.0
WLSH2_k127_3072565_12 Nucleotidyltransferase domain K07075 - - 0.0000000002398 64.0
WLSH2_k127_3072565_13 DNA polymerase beta domain protein region K07075 - - 0.0000004685 54.0
WLSH2_k127_3072565_14 Protein of unknown function DUF86 - - - 0.00001629 48.0
WLSH2_k127_3072565_15 Protein of unknown function DUF86 - - - 0.0006343 43.0
WLSH2_k127_3072565_2 CotH kinase protein K06330 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 375.0
WLSH2_k127_3072565_3 Major Facilitator K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 367.0
WLSH2_k127_3072565_4 - K20328 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 324.0
WLSH2_k127_3072565_5 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 301.0
WLSH2_k127_3072565_6 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000126 228.0
WLSH2_k127_3072565_7 Bacterial cellulose synthase subunit - - - 0.00000000000000000000000000000000000000000000000000000000002865 229.0
WLSH2_k127_3072565_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000006287 149.0
WLSH2_k127_3072565_9 - - - - 0.00000000000000000000000000000006931 136.0
WLSH2_k127_3095596_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 447.0
WLSH2_k127_3095596_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 362.0
WLSH2_k127_3095596_2 cell division K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 310.0
WLSH2_k127_3096878_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.561e-309 956.0
WLSH2_k127_3096878_1 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 528.0
WLSH2_k127_3096878_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003701 256.0
WLSH2_k127_3113752_0 PFAM AsmA family protein K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 559.0
WLSH2_k127_3113752_1 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000001896 136.0
WLSH2_k127_3113752_3 - - - - 0.00004235 54.0
WLSH2_k127_3120656_0 Sigma-54 interaction domain K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 4.441e-212 667.0
WLSH2_k127_3120656_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 484.0
WLSH2_k127_3120656_2 signal transduction histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 430.0
WLSH2_k127_3120656_3 PFAM Exonuclease, RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
WLSH2_k127_3120656_4 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000001641 192.0
WLSH2_k127_3120656_5 Domain of unknown function (DUF4124) - - - 0.0000000000007882 76.0
WLSH2_k127_3143107_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 546.0
WLSH2_k127_3147829_0 COG2206 HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 327.0
WLSH2_k127_3147829_1 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000001603 240.0
WLSH2_k127_3147829_2 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000769 224.0
WLSH2_k127_3147829_3 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000000000003456 203.0
WLSH2_k127_3147829_4 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000001445 167.0
WLSH2_k127_3147829_5 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000001374 145.0
WLSH2_k127_3147829_6 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000001533 76.0
WLSH2_k127_3163773_0 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000129 232.0
WLSH2_k127_3163773_1 ATPase with chaperone activity K07391 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
WLSH2_k127_3163773_2 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000001878 198.0
WLSH2_k127_3163773_3 TIGRFAM conserved - - - 0.0000000000000000000000000000004998 138.0
WLSH2_k127_3163773_4 Membrane fusogenic activity K09806 - - 0.00000000000000000000302 95.0
WLSH2_k127_3215031_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.008e-220 692.0
WLSH2_k127_3215031_1 Radical SAM superfamily K04069 - 1.97.1.4 4.791e-204 639.0
WLSH2_k127_3215031_10 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000001253 108.0
WLSH2_k127_3215031_11 - - - - 0.00000000000000000000000019 108.0
WLSH2_k127_3215031_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 606.0
WLSH2_k127_3215031_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 501.0
WLSH2_k127_3215031_4 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 428.0
WLSH2_k127_3215031_5 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006304,GO:0006305,GO:0006306,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009007,GO:0009008,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0032775,GO:0034641,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044728,GO:0046483,GO:0071704,GO:0090304,GO:0140096,GO:0140097,GO:1901360,GO:1901564 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 381.0
WLSH2_k127_3215031_6 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 353.0
WLSH2_k127_3215031_7 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 285.0
WLSH2_k127_3215031_8 pfam ammecr1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008462 238.0
WLSH2_k127_3215031_9 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000005847 107.0
WLSH2_k127_3225197_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.27e-236 739.0
WLSH2_k127_3225197_1 Colicin v production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.0000000000000000000000000000000000000000000000004817 180.0
WLSH2_k127_3225197_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000003097 163.0
WLSH2_k127_3225197_3 Sporulation related domain K03749 - - 0.0000000000000000000005081 107.0
WLSH2_k127_3225197_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00000000000000001964 82.0
WLSH2_k127_3256752_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1296.0
WLSH2_k127_3256752_1 Allophanate hydrolase K01457 - 3.5.1.54 6.55e-217 690.0
WLSH2_k127_3256752_2 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 437.0
WLSH2_k127_3256752_3 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003175 265.0
WLSH2_k127_3256752_4 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000001806 203.0
WLSH2_k127_3256752_5 Belongs to the UPF0125 (RnfH) family K09801 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0055114 - 0.00000000000000000000001385 103.0
WLSH2_k127_3310881_0 Polysaccharide biosynthesis/export protein - - - 5.107e-206 658.0
WLSH2_k127_3310881_1 COG3524 Capsule polysaccharide export protein K10107 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 413.0
WLSH2_k127_3310881_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 335.0
WLSH2_k127_3310881_3 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000002358 177.0
WLSH2_k127_3310881_4 Hydrolase - - - 0.000000000000000000000000005796 112.0
WLSH2_k127_3321929_0 von Willebrand factor (vWF) type A domain K02448 - - 4.645e-226 715.0
WLSH2_k127_3321929_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 442.0
WLSH2_k127_3321929_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 395.0
WLSH2_k127_3321929_3 Cytochrome c oxidase subunit III K02164,K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001733 258.0
WLSH2_k127_3321929_4 - - - - 0.00000000000000000000000000000001224 131.0
WLSH2_k127_3321929_5 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000000393 58.0
WLSH2_k127_3323507_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 518.0
WLSH2_k127_3323507_1 PFAM Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 488.0
WLSH2_k127_3323507_2 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 307.0
WLSH2_k127_3323507_3 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000954 205.0
WLSH2_k127_3323507_4 Thioredoxin-like - - - 0.000000000000000000000000001607 119.0
WLSH2_k127_3323507_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000002878 83.0
WLSH2_k127_3323507_6 Protein conserved in bacteria K07465 - - 0.00000000001509 72.0
WLSH2_k127_3332534_0 cation transport ATPase K01533 - 3.6.3.4 2.47e-322 1005.0
WLSH2_k127_3332534_1 TIGRFAM cytochrome c oxidase accessory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 608.0
WLSH2_k127_3332534_2 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 345.0
WLSH2_k127_3332534_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 341.0
WLSH2_k127_3332534_4 - - - - 0.000000000000000000000000000000000000000000000209 177.0
WLSH2_k127_3332534_5 PFAM FixH - - - 0.000000000000000000000000000000005507 134.0
WLSH2_k127_3332534_6 - - - - 0.000000000000000000000000005366 116.0
WLSH2_k127_3332534_7 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000003348 81.0
WLSH2_k127_3332534_8 PFAM cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000001646 75.0
WLSH2_k127_3332534_9 Cbb3-type cytochrome oxidase component FixQ - - - 0.00000001723 58.0
WLSH2_k127_3366737_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 341.0
WLSH2_k127_3366737_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003863 279.0
WLSH2_k127_3366737_2 Pfam Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004415 235.0
WLSH2_k127_3366737_3 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000005439 92.0
WLSH2_k127_3366737_4 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.0000008507 51.0
WLSH2_k127_3385678_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.653e-212 670.0
WLSH2_k127_3385678_1 Sporulation related domain - - - 0.00000000000000000001318 97.0
WLSH2_k127_3392329_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 546.0
WLSH2_k127_341718_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 576.0
WLSH2_k127_341718_1 PFAM CHASE2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 344.0
WLSH2_k127_341718_2 urea ABC transporter, ATP-binding protein K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009417 243.0
WLSH2_k127_341718_3 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000002294 210.0
WLSH2_k127_3428205_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 7.654e-287 885.0
WLSH2_k127_3428205_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 610.0
WLSH2_k127_3428205_2 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 428.0
WLSH2_k127_3428205_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 383.0
WLSH2_k127_3428205_4 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000005737 224.0
WLSH2_k127_3437144_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.272e-220 693.0
WLSH2_k127_3437144_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.0000000000000000000000119 108.0
WLSH2_k127_3460374_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059,K03793 - 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 321.0
WLSH2_k127_3460374_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000003622 218.0
WLSH2_k127_3467020_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 7.092e-201 638.0
WLSH2_k127_3467020_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 353.0
WLSH2_k127_3467020_10 Dienelactone hydrolase family - - - 0.0000000000000000000000002017 106.0
WLSH2_k127_3467020_11 Membrane - - - 0.00000000000000008903 89.0
WLSH2_k127_3467020_12 Protein of Unknown function (DUF2784) - - - 0.0000000000000009384 81.0
WLSH2_k127_3467020_13 - - - - 0.0000000005658 64.0
WLSH2_k127_3467020_2 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 344.0
WLSH2_k127_3467020_3 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 322.0
WLSH2_k127_3467020_4 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005225 244.0
WLSH2_k127_3467020_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000005577 223.0
WLSH2_k127_3467020_6 PFAM FAD dependent oxidoreductase K00105,K00111 - 1.1.3.21,1.1.5.3 0.00000000000000000000000000000000000000000000000000000002149 216.0
WLSH2_k127_3467020_7 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000004468 152.0
WLSH2_k127_3467020_8 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000004464 153.0
WLSH2_k127_3467020_9 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000004674 123.0
WLSH2_k127_347379_0 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 317.0
WLSH2_k127_347379_1 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000005641 177.0
WLSH2_k127_347379_2 - - - - 0.000000000000000000008821 96.0
WLSH2_k127_3505930_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 441.0
WLSH2_k127_3505930_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 383.0
WLSH2_k127_3505930_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000001734 124.0
WLSH2_k127_3505930_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000001134 58.0
WLSH2_k127_3536105_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 293.0
WLSH2_k127_3536105_1 Competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000007138 231.0
WLSH2_k127_3536105_2 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000015 148.0
WLSH2_k127_3596783_0 ABC transporter transmembrane region K06148 - - 2.161e-254 799.0
WLSH2_k127_3596783_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.969e-207 653.0
WLSH2_k127_3596783_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001308 261.0
WLSH2_k127_3596783_3 phenylacetate-CoA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002061 222.0
WLSH2_k127_3596783_4 HDOD domain - - - 0.0000000000000000000000000000000000000000007652 168.0
WLSH2_k127_3596783_5 DNA topological change - - - 0.0000000000000000002855 96.0
WLSH2_k127_3596783_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000002313 58.0
WLSH2_k127_3615267_0 Ompa motb domain protein - - - 1.708e-255 801.0
WLSH2_k127_3615267_1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 301.0
WLSH2_k127_3615724_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 392.0
WLSH2_k127_3615724_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000001369 196.0
WLSH2_k127_3635778_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 295.0
WLSH2_k127_3635778_1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000001313 124.0
WLSH2_k127_3635778_2 Belongs to the ompA family K03286 - - 0.000000000000000000000000000004578 128.0
WLSH2_k127_3635778_3 FxsA cytoplasmic membrane protein K07113 - - 0.00000000000000000000007825 105.0
WLSH2_k127_3659812_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1184.0
WLSH2_k127_3659812_1 penicillin-binding protein K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 3.231e-270 854.0
WLSH2_k127_3659812_10 Protein of unknown function (DUF3135) - - - 0.000000000000000006975 87.0
WLSH2_k127_3659812_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.568e-233 729.0
WLSH2_k127_3659812_3 PFAM malic K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 595.0
WLSH2_k127_3659812_4 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 555.0
WLSH2_k127_3659812_5 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 450.0
WLSH2_k127_3659812_6 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000155 198.0
WLSH2_k127_3659812_7 mRNA catabolic process - - - 0.0000000000000000000000000000000000000000000000000001972 191.0
WLSH2_k127_3659812_8 nuclease - - - 0.00000000000000000000000000000000000000000002329 173.0
WLSH2_k127_3659812_9 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000059 130.0
WLSH2_k127_366827_0 Cytochrome c - - - 1.154e-254 796.0
WLSH2_k127_366827_2 SCO1 SenC K07152 - - 0.0000000000000000000002238 96.0
WLSH2_k127_3685415_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 390.0
WLSH2_k127_3685415_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 286.0
WLSH2_k127_3685415_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001323 278.0
WLSH2_k127_3685415_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000003577 108.0
WLSH2_k127_3685415_4 Domain of unknown function (DUF4845) - - - 0.0000000000006889 74.0
WLSH2_k127_3696251_0 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 577.0
WLSH2_k127_3696251_1 glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 428.0
WLSH2_k127_3696251_2 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 319.0
WLSH2_k127_3696251_3 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 279.0
WLSH2_k127_3719278_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.117e-283 888.0
WLSH2_k127_3719278_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000118 166.0
WLSH2_k127_3735586_0 COG0811 Biopolymer transport proteins K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0017038,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0032153,GO:0033036,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002624 273.0
WLSH2_k127_3735586_1 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000000008827 169.0
WLSH2_k127_3735586_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000004974 153.0
WLSH2_k127_3735586_3 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000004305 128.0
WLSH2_k127_3752360_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1178.0
WLSH2_k127_3752360_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 402.0
WLSH2_k127_3752360_2 CorA-like Mg2+ transporter protein K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 330.0
WLSH2_k127_3752360_3 NlpC/P60 family - - - 0.0000000000000000000000000000000402 136.0
WLSH2_k127_3752360_4 - - - - 0.0000005258 52.0
WLSH2_k127_3793985_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1685.0
WLSH2_k127_3793985_1 synthase component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 460.0
WLSH2_k127_3793985_2 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 389.0
WLSH2_k127_3793985_3 CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 383.0
WLSH2_k127_3793985_4 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 376.0
WLSH2_k127_3793985_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000008253 175.0
WLSH2_k127_3793985_6 RepB DNA-primase from phage plasmid - - - 0.00000000003562 71.0
WLSH2_k127_3794746_0 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 435.0
WLSH2_k127_3794746_1 Class III cytochrome C family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 346.0
WLSH2_k127_3794746_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001902 264.0
WLSH2_k127_3794746_3 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000005312 214.0
WLSH2_k127_3838311_0 Predicted methyltransferase regulatory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 413.0
WLSH2_k127_3838311_1 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000000000000000000000000000021 157.0
WLSH2_k127_385759_0 RNA polymerase recycling family C-terminal K03580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 459.0
WLSH2_k127_385759_1 peptidyl-prolyl K03775 - 5.2.1.8 0.000000000000000000000000002634 120.0
WLSH2_k127_385759_2 Protein of unknown function (DUF971) - - - 0.00000000000000000000004299 102.0
WLSH2_k127_3871122_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 2.686e-226 718.0
WLSH2_k127_3871122_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 7.459e-207 653.0
WLSH2_k127_3871122_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 442.0
WLSH2_k127_3871122_3 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002319 276.0
WLSH2_k127_3871122_4 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003677 272.0
WLSH2_k127_3871346_0 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003664 291.0
WLSH2_k127_3871346_1 aminotransferase class I and II - - - 0.0000000000000000000001279 101.0
WLSH2_k127_3871346_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000002929 58.0
WLSH2_k127_3882155_0 Citrate transporter - - - 1.549e-199 631.0
WLSH2_k127_3882155_1 UPF0056 membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001462 240.0
WLSH2_k127_3887614_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 484.0
WLSH2_k127_3887614_1 NMT1-like family K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 476.0
WLSH2_k127_3887614_2 TIGRFAM nitrate ABC transporter, ATPase subunits C and D K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 426.0
WLSH2_k127_3887614_3 transporter, permease K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
WLSH2_k127_3898526_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 424.0
WLSH2_k127_3898526_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000001026 216.0
WLSH2_k127_3898526_2 Protein of unknown function (DUF2288) - - - 0.00000000000000000000000001099 112.0
WLSH2_k127_3898526_3 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.00000000000000000000000002966 111.0
WLSH2_k127_3898526_4 dicarboxylic acid transport - - - 0.00000000001318 67.0
WLSH2_k127_3929721_0 ResB-like family K07399 - - 7.445e-195 629.0
WLSH2_k127_3929721_1 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 541.0
WLSH2_k127_3929721_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000006133 154.0
WLSH2_k127_3929721_3 COG2863 Cytochrome c553 - - - 0.000000000000000000000000009597 110.0
WLSH2_k127_3937999_0 signal transduction histidine kinase - - - 1.836e-215 691.0
WLSH2_k127_3937999_1 PFAM TrkA-N domain K03499 - - 1.317e-203 642.0
WLSH2_k127_3937999_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 4.805e-200 633.0
WLSH2_k127_3937999_3 response regulator receiver K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 558.0
WLSH2_k127_3937999_4 PFAM Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000002205 208.0
WLSH2_k127_3970479_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 3.185e-274 864.0
WLSH2_k127_3970479_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.395e-243 755.0
WLSH2_k127_3970479_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 9.787e-227 707.0
WLSH2_k127_3970479_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 518.0
WLSH2_k127_3970479_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 325.0
WLSH2_k127_3970479_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001523 261.0
WLSH2_k127_3970479_6 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000004293 234.0
WLSH2_k127_3970479_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000004234 223.0
WLSH2_k127_3970479_8 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000006771 77.0
WLSH2_k127_4038646_0 Part of a membrane complex involved in electron transport K03615 - - 6.15e-207 657.0
WLSH2_k127_4038646_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 402.0
WLSH2_k127_4038646_2 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000000000000000000000000001398 229.0
WLSH2_k127_4038646_3 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000001916 216.0
WLSH2_k127_4038646_4 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000001055 170.0
WLSH2_k127_4079923_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 509.0
WLSH2_k127_4079923_1 DNA polymerase III alpha subunit K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004432 273.0
WLSH2_k127_4079923_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000007979 160.0
WLSH2_k127_4081273_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.731e-250 782.0
WLSH2_k127_4081273_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.478e-207 647.0
WLSH2_k127_4081273_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 533.0
WLSH2_k127_4081273_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000001958 191.0
WLSH2_k127_4081273_4 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000001214 170.0
WLSH2_k127_4081273_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009226,GO:0009987,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0034654,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000005989 128.0
WLSH2_k127_408456_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 413.0
WLSH2_k127_408456_1 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 327.0
WLSH2_k127_408456_2 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000001026 179.0
WLSH2_k127_408456_3 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000001175 137.0
WLSH2_k127_4088802_0 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 444.0
WLSH2_k127_4088802_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 383.0
WLSH2_k127_4088802_2 N-terminal domain of ribose phosphate pyrophosphokinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 342.0
WLSH2_k127_4088802_3 Thymidine phosphorylase K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006004 267.0
WLSH2_k127_4088802_4 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006572 241.0
WLSH2_k127_4103945_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 520.0
WLSH2_k127_4103945_1 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 357.0
WLSH2_k127_4103945_2 High frequency lysogenization protein HflD homolog K07153 - - 0.000000000000000000000000000000000000000000000000000006856 196.0
WLSH2_k127_4103945_3 Cytochrome K12262 - - 0.000000000000000000000000000000000000000000000000889 180.0
WLSH2_k127_4103945_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000004464 168.0
WLSH2_k127_4103945_5 RNA pseudouridylate synthase K06181 - 5.4.99.20 0.00000000000000000000000000000483 123.0
WLSH2_k127_4121181_0 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 366.0
WLSH2_k127_4121181_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 335.0
WLSH2_k127_4121181_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004331 254.0
WLSH2_k127_4121181_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000238 207.0
WLSH2_k127_4121181_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.000000000000000009399 90.0
WLSH2_k127_4146951_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 502.0
WLSH2_k127_4146951_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 404.0
WLSH2_k127_4146951_10 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000004352 61.0
WLSH2_k127_4146951_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 384.0
WLSH2_k127_4146951_3 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 304.0
WLSH2_k127_4146951_4 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001683 277.0
WLSH2_k127_4146951_5 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000005351 199.0
WLSH2_k127_4146951_6 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000001467 200.0
WLSH2_k127_4146951_7 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000006665 143.0
WLSH2_k127_4146951_8 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000122 115.0
WLSH2_k127_4146951_9 Protein of unknown function (DUF2892) - - - 0.0000000000000001585 80.0
WLSH2_k127_4149217_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 574.0
WLSH2_k127_4166141_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
WLSH2_k127_4166141_1 PFAM FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000001297 227.0
WLSH2_k127_4166141_2 Phosphoesterase K07095 - - 0.00000000000000000000000000000000004857 136.0
WLSH2_k127_4174_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1062.0
WLSH2_k127_4174_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 326.0
WLSH2_k127_4174_2 Nlpbdapx family lipoprotein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000001586 223.0
WLSH2_k127_4174_3 CbiX K03794 - 4.99.1.4 0.000000000000000000000000000004871 124.0
WLSH2_k127_4174088_0 SNF2 family N-terminal domain - - - 2.942e-279 869.0
WLSH2_k127_4197962_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006725 481.0
WLSH2_k127_4197962_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 467.0
WLSH2_k127_4197962_2 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000001295 244.0
WLSH2_k127_4197962_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.0000000000000000000000000000000000000000000000000000000008509 209.0
WLSH2_k127_4198868_0 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 422.0
WLSH2_k127_4198868_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002018 273.0
WLSH2_k127_4198868_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000001592 182.0
WLSH2_k127_4198868_3 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000007444 186.0
WLSH2_k127_4208679_0 SMART Phospholipid glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.233e-211 670.0
WLSH2_k127_4208679_1 PFAM Major Facilitator Superfamily K08227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 392.0
WLSH2_k127_4230991_0 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 1.194e-228 713.0
WLSH2_k127_4230991_1 PFAM Aminotransferase, class I K14261 - - 2.37e-220 688.0
WLSH2_k127_4230991_2 Homoserine dehydrogenase K00003 - 1.1.1.3 2.118e-208 655.0
WLSH2_k127_4230991_3 threonine synthase K01733 - 4.2.3.1 1.634e-207 647.0
WLSH2_k127_4230991_4 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70 sigma32) K03087 GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 413.0
WLSH2_k127_4230991_5 single-stranded-DNA-specific exonuclease RecJ K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000006579 217.0
WLSH2_k127_4230991_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000009601 149.0
WLSH2_k127_4230991_7 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000007932 105.0
WLSH2_k127_4249433_0 Surface antigen variable number K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 451.0
WLSH2_k127_4249433_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0008692 46.0
WLSH2_k127_4261206_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 486.0
WLSH2_k127_4261206_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 296.0
WLSH2_k127_4261206_2 Mota tolq exbb proton channel K03561 - - 0.000000000000000000000000000008781 119.0
WLSH2_k127_4261206_3 Pfam Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000000000073 111.0
WLSH2_k127_4282682_0 PFAM Polyphosphate kinase 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 524.0
WLSH2_k127_4282682_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 298.0
WLSH2_k127_4291606_0 PFAM peptidase K08303 - - 1.452e-211 664.0
WLSH2_k127_4291606_1 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000000002762 152.0
WLSH2_k127_4294305_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 335.0
WLSH2_k127_4294305_1 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000004357 216.0
WLSH2_k127_4294305_2 Clan AA aspartic protease K06985 - - 0.0000001331 55.0
WLSH2_k127_431674_0 PFAM binding-protein-dependent transport systems inner membrane component K02037 - - 1.291e-276 870.0
WLSH2_k127_431674_1 Phosphate transport system permease protein K02038 - - 1.997e-246 772.0
WLSH2_k127_431674_10 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000009027 231.0
WLSH2_k127_431674_11 WLM domain K07043 - - 0.000000000000000000000000000000000000000000000000000004791 198.0
WLSH2_k127_431674_12 - - - - 0.0000000000000000000000000000000000000000000000000003841 188.0
WLSH2_k127_431674_13 - - - - 0.00000000000000000000000000002962 120.0
WLSH2_k127_431674_14 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.0000000000000000000005678 98.0
WLSH2_k127_431674_16 - - - - 0.0000000000002202 76.0
WLSH2_k127_431674_17 ABC transporter, substrate-binding protein, family 5 K13893 - - 0.000000000001364 68.0
WLSH2_k127_431674_19 Bacterial protein of unknown function (DUF937) K03286 - - 0.0000000007007 67.0
WLSH2_k127_431674_2 COG4992 Ornithine acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 555.0
WLSH2_k127_431674_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 445.0
WLSH2_k127_431674_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 439.0
WLSH2_k127_431674_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 342.0
WLSH2_k127_431674_6 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 314.0
WLSH2_k127_431674_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 301.0
WLSH2_k127_431674_8 Phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 290.0
WLSH2_k127_431674_9 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000009305 239.0
WLSH2_k127_4415279_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 447.0
WLSH2_k127_4415279_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000001107 227.0
WLSH2_k127_443618_0 4Fe-4S single cluster domain - - - 2.014e-222 700.0
WLSH2_k127_443618_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004634 277.0
WLSH2_k127_443618_2 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000001476 231.0
WLSH2_k127_443618_3 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000003289 102.0
WLSH2_k127_4479868_0 Hint domain - - - 0.000000000000000000000000000000000000000000000009904 184.0
WLSH2_k127_4479868_1 Glycosyltransferase sugar-binding region containing DXD motif - - - 0.000000000000000000000000000000000000000000003977 182.0
WLSH2_k127_4479868_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000002262 103.0
WLSH2_k127_4479868_3 Tetratricopeptide repeat - - - 0.0005208 49.0
WLSH2_k127_4494896_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 609.0
WLSH2_k127_4494896_1 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 405.0
WLSH2_k127_4494896_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 293.0
WLSH2_k127_4508546_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 450.0
WLSH2_k127_4508546_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 342.0
WLSH2_k127_4508546_10 SMART Mov34 MPN PAD-1 family protein - - - 0.000000000000000000000000000000000000003034 151.0
WLSH2_k127_4508546_11 - - - - 0.000000000000000000000000000000000003461 139.0
WLSH2_k127_4508546_12 nitric oxide dioxygenase activity K07140 - - 0.000000000000000000000000000001382 126.0
WLSH2_k127_4508546_13 CheW-like domain - - - 0.00000000000004046 79.0
WLSH2_k127_4508546_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K03148,K21029 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0061605,GO:0070566,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 334.0
WLSH2_k127_4508546_3 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 310.0
WLSH2_k127_4508546_4 Oxidoreductase, FAD-binding K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000007214 267.0
WLSH2_k127_4508546_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000002676 223.0
WLSH2_k127_4508546_6 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000001148 194.0
WLSH2_k127_4508546_7 consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000007146 173.0
WLSH2_k127_4508546_8 Response regulator receiver K02658 - - 0.000000000000000000000000000000000000000007294 156.0
WLSH2_k127_4508546_9 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.0000000000000000000000000000000000000002632 157.0
WLSH2_k127_4509523_0 - - - - 0.00000000000000000000000000000000000000000000000007842 188.0
WLSH2_k127_4509523_1 Cytochrome c - - - 0.0000000000000000000005979 107.0
WLSH2_k127_4509523_2 pfam nudix K03574 - 3.6.1.55 0.00000000002526 64.0
WLSH2_k127_4511949_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 7.892e-202 644.0
WLSH2_k127_4511949_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 493.0
WLSH2_k127_4511949_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 380.0
WLSH2_k127_4511949_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000003706 166.0
WLSH2_k127_4511949_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000001136 88.0
WLSH2_k127_4521035_0 ABC transporter K06158 - - 1.2e-253 797.0
WLSH2_k127_4521035_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 359.0
WLSH2_k127_4521035_2 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000003946 214.0
WLSH2_k127_4521035_3 Belongs to the SlyX family K03745 - - 0.0000132 49.0
WLSH2_k127_4537685_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 347.0
WLSH2_k127_4537685_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004832 281.0
WLSH2_k127_4537685_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
WLSH2_k127_4537685_3 TIGRFAM CRISPR-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004916 234.0
WLSH2_k127_4537685_4 COG0470 ATPase involved in DNA replication K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000005217 196.0
WLSH2_k127_4537685_5 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000009522 158.0
WLSH2_k127_4537685_6 - - - - 0.000000000000000000000000000000000001566 146.0
WLSH2_k127_4541387_0 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 462.0
WLSH2_k127_4541387_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 380.0
WLSH2_k127_4541387_2 - - - - 0.00000000000000000000000003033 115.0
WLSH2_k127_4557590_0 PFAM EAL domain K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 515.0
WLSH2_k127_4557590_1 Peptidase family M48 K03799 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 397.0
WLSH2_k127_4723061_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 588.0
WLSH2_k127_4723061_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 521.0
WLSH2_k127_4723061_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 338.0
WLSH2_k127_4723061_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 300.0
WLSH2_k127_4723061_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002519 249.0
WLSH2_k127_4723061_5 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000007374 236.0
WLSH2_k127_4723061_6 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004151 228.0
WLSH2_k127_4741339_0 TIGRFAM Nitrogenase cofactor biosynthesis protein NifB K02585 - - 1.417e-230 723.0
WLSH2_k127_4741339_1 PFAM NifQ family protein K15790 - - 0.00000000000000000000000000000000000000000000001648 177.0
WLSH2_k127_4741339_2 ArsC family - - - 0.0000000000000000000000000000000000000000002261 164.0
WLSH2_k127_4741339_3 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000001682 136.0
WLSH2_k127_4741339_4 ADP-ribosyl-(Dinitrogen reductase) hydrolase K05521 - 3.2.2.24 0.0000000000000000001415 91.0
WLSH2_k127_4741339_5 Protein SSUH2 homolog - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0007275,GO:0008150,GO:0009653,GO:0009887,GO:0032501,GO:0032502,GO:0042476,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0048513,GO:0048731,GO:0048856 - 0.00001072 57.0
WLSH2_k127_4769587_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 1.574e-246 771.0
WLSH2_k127_4769587_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.215e-206 649.0
WLSH2_k127_4769587_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000000000000000000000000000001011 236.0
WLSH2_k127_4769587_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001613 233.0
WLSH2_k127_4775408_0 STAS domain - - - 7.731e-209 670.0
WLSH2_k127_4775408_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 305.0
WLSH2_k127_4775408_2 Stringent starvation protein A K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008323 256.0
WLSH2_k127_4775408_3 COG2969 Stringent starvation protein B K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.0000000000000000000000000000000000000000101 156.0
WLSH2_k127_4775408_4 Cytochrome C1 family K00413 - - 0.00000000000000000000000005288 108.0
WLSH2_k127_4789558_0 Ammonium Transporter K03320 - - 2.289e-202 646.0
WLSH2_k127_4789558_1 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 454.0
WLSH2_k127_4789558_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043918,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 395.0
WLSH2_k127_4789558_3 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 294.0
WLSH2_k127_4789558_4 Gram-negative porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 298.0
WLSH2_k127_4789558_5 nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000002255 198.0
WLSH2_k127_4789558_6 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000003231 137.0
WLSH2_k127_4789558_7 ABC-type phosphate transport system, periplasmic component - - - 0.0000000000000000000000005315 109.0
WLSH2_k127_4789558_8 Sel1-like repeats. K07126 - - 0.00000001658 59.0
WLSH2_k127_4792960_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 521.0
WLSH2_k127_4792960_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 426.0
WLSH2_k127_479529_0 Protein of unknown function (DUF1538) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 374.0
WLSH2_k127_479529_1 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000004444 218.0
WLSH2_k127_479529_2 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
WLSH2_k127_479529_3 Belongs to the P(II) protein family - - - 0.000000000000000000000000000000000000000000005152 178.0
WLSH2_k127_479529_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000009151 127.0
WLSH2_k127_4806853_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 498.0
WLSH2_k127_4806853_1 GTP-binding protein TypA K06207 - - 0.0000000000000000000000000000000000000000000000000000002038 195.0
WLSH2_k127_4806853_2 Belongs to the ompA family - - - 0.000000000000000000000000000000000000002 155.0
WLSH2_k127_4806853_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000002769 127.0
WLSH2_k127_488475_0 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 301.0
WLSH2_k127_488475_1 PFAM Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000001762 209.0
WLSH2_k127_488475_2 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000002783 184.0
WLSH2_k127_488475_3 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000004008 136.0
WLSH2_k127_488475_4 Domain of unknown function (DUF1924) - - - 0.00000000000000000000008456 101.0
WLSH2_k127_488475_5 - - - - 0.0000000000000002093 86.0
WLSH2_k127_488475_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000003253 81.0
WLSH2_k127_4889866_0 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 509.0
WLSH2_k127_4889866_1 - - - - 0.000000000000000000000000000000000000000000000003057 188.0
WLSH2_k127_4889866_2 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000000000000000000000404 147.0
WLSH2_k127_4889866_3 von Willebrand factor, type A - - - 0.000000000001853 66.0
WLSH2_k127_4889866_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00005941 48.0
WLSH2_k127_4901896_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1064.0
WLSH2_k127_4901896_1 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 322.0
WLSH2_k127_4901896_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 317.0
WLSH2_k127_4901896_3 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000001421 112.0
WLSH2_k127_491344_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1949.0
WLSH2_k127_491344_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1518.0
WLSH2_k127_4933327_0 glutamate synthase - - - 3.893e-284 883.0
WLSH2_k127_4933327_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 473.0
WLSH2_k127_4933327_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000008962 215.0
WLSH2_k127_4937221_0 - - - - 0.000000000000000000001704 109.0
WLSH2_k127_4941693_0 Glucose-1-phosphate adenylyltransferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 562.0
WLSH2_k127_4941693_1 - - - - 0.000000000000000000000000000000000000000000000001396 182.0
WLSH2_k127_4941693_2 COG1278 Cold shock proteins - - - 0.000000000000000000000001416 107.0
WLSH2_k127_4999647_0 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 388.0
WLSH2_k127_4999647_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007088 250.0
WLSH2_k127_4999647_2 - - - - 0.000004111 50.0
WLSH2_k127_5000931_0 glutamine synthetase K01915 - 6.3.1.2 1.112e-272 841.0
WLSH2_k127_5000931_1 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 493.0
WLSH2_k127_5000931_2 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 334.0
WLSH2_k127_5000931_3 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 336.0
WLSH2_k127_5000931_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 295.0
WLSH2_k127_5000931_5 NikR C terminal nickel binding domain K07722 - - 0.000000000000000000000000000000000000000000000000000000000000203 215.0
WLSH2_k127_5004544_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006357 372.0
WLSH2_k127_5004544_1 SAM-dependent K06969 - 2.1.1.191 0.00000000000000000000563 93.0
WLSH2_k127_5011706_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 461.0
WLSH2_k127_5011706_1 Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 368.0
WLSH2_k127_5011706_2 Squalene/phytoene synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 305.0
WLSH2_k127_5011706_3 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 299.0
WLSH2_k127_5011706_4 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000005236 264.0
WLSH2_k127_5046364_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 358.0
WLSH2_k127_5046364_1 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000614 205.0
WLSH2_k127_5046364_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000001357 88.0
WLSH2_k127_5077534_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.954e-228 712.0
WLSH2_k127_5077534_1 AntiSigma factor - - - 0.000000000000000000000000000000000000003423 158.0
WLSH2_k127_5077534_2 Sigma-70, region 4 - - - 0.000000000000000000000439 97.0
WLSH2_k127_5082647_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 481.0
WLSH2_k127_5082647_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 452.0
WLSH2_k127_5094547_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.02e-206 660.0
WLSH2_k127_5094547_1 ABC transporter transmembrane region K12541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 572.0
WLSH2_k127_5094547_2 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 389.0
WLSH2_k127_510369_0 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000000000000616 203.0
WLSH2_k127_510369_1 PFAM EAL domain protein - - - 0.00000000000000001965 85.0
WLSH2_k127_510445_0 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 469.0
WLSH2_k127_5153814_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 369.0
WLSH2_k127_5153814_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004079 235.0
WLSH2_k127_5153814_2 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000006793 194.0
WLSH2_k127_5153814_3 Protein of unknown function (DUF805) - - - 0.000000000000000000000000000000000000000000002702 166.0
WLSH2_k127_5153814_4 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000001661 162.0
WLSH2_k127_5182260_0 PFAM Fructosamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 384.0
WLSH2_k127_5182260_1 Sulfotransferase domain K13472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 330.0
WLSH2_k127_5182260_2 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000614 245.0
WLSH2_k127_5182260_3 Hint domain - - - 0.000000000000000000000000000000004765 145.0
WLSH2_k127_5182260_5 Arac family - - - 0.0000000006833 62.0
WLSH2_k127_5182260_6 Glycosyltransferase sugar-binding region containing DXD motif - - - 0.0000000008899 72.0
WLSH2_k127_5218669_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 323.0
WLSH2_k127_5218669_1 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001863 245.0
WLSH2_k127_5218669_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006162 240.0
WLSH2_k127_5232405_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 584.0
WLSH2_k127_5232405_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000006114 198.0
WLSH2_k127_5232405_2 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000001124 94.0
WLSH2_k127_5232405_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000005548 51.0
WLSH2_k127_5251918_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 464.0
WLSH2_k127_5251918_1 PFAM UBA THIF-type NAD FAD binding K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 309.0
WLSH2_k127_5251918_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002633 271.0
WLSH2_k127_5253229_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 5.566e-217 687.0
WLSH2_k127_5253229_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 606.0
WLSH2_k127_5253229_2 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 411.0
WLSH2_k127_5253229_3 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 396.0
WLSH2_k127_5253229_4 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 361.0
WLSH2_k127_5253229_5 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 344.0
WLSH2_k127_5253229_6 PFAM methyltransferase small - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 297.0
WLSH2_k127_5256541_0 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001374 278.0
WLSH2_k127_5256541_1 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000000000000000000000001051 151.0
WLSH2_k127_5256541_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000007633 147.0
WLSH2_k127_5267818_0 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 350.0
WLSH2_k127_5267818_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007584,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009605,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019222,GO:0019438,GO:0030551,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0032553,GO:0032555,GO:0032561,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0035438,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045013,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045990,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0061984,GO:0061985,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140110,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 319.0
WLSH2_k127_5267818_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000004517 235.0
WLSH2_k127_5267818_3 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000004877 228.0
WLSH2_k127_5267818_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000004803 196.0
WLSH2_k127_5267818_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.00000000000000000000000000000000000000000039 160.0
WLSH2_k127_5280990_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 GO:0000166,GO:0001000,GO:0003674,GO:0003676,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 488.0
WLSH2_k127_5280990_1 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 484.0
WLSH2_k127_5280990_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004565 275.0
WLSH2_k127_5280990_3 transcriptional regulators - - - 0.00000000000000000000000000000000000000003405 154.0
WLSH2_k127_5280990_4 Protein of unknown function (DUF504) - - - 0.0000000000000000000000000001372 117.0
WLSH2_k127_5309657_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 469.0
WLSH2_k127_5309657_1 Outer membrane protein, 28 kDa K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000009572 112.0
WLSH2_k127_5311557_0 Belongs to the EPSP synthase family. MurA subfamily K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 1.845e-202 636.0
WLSH2_k127_5311557_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 421.0
WLSH2_k127_5311557_2 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 381.0
WLSH2_k127_5311557_3 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000007142 194.0
WLSH2_k127_5311557_4 MlaD protein K02067 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008289,GO:0016020,GO:0016021,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043167,GO:0043168,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000002234 189.0
WLSH2_k127_5311557_5 Belongs to the BolA IbaG family - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.0000000000000000000002368 98.0
WLSH2_k127_5311557_6 NTP binding protein (Contains STAS domain) K07122 - - 0.000000000000001082 83.0
WLSH2_k127_5343409_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.598e-207 653.0
WLSH2_k127_5343409_1 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000000000000000000393 204.0
WLSH2_k127_5343409_2 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000001921 173.0
WLSH2_k127_5343409_3 Putative heavy-metal-binding - - - 0.0000000000000000000000000000000000000000000003741 171.0
WLSH2_k127_5343409_4 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000005937 167.0
WLSH2_k127_5343409_5 - - - - 0.0000000000000000000000000000000000000000001396 168.0
WLSH2_k127_5343409_6 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000371 154.0
WLSH2_k127_5349554_0 lysine 2,3-aminomutase - - - 1.238e-205 648.0
WLSH2_k127_5349554_1 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000006852 98.0
WLSH2_k127_5361041_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 505.0
WLSH2_k127_5361041_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000007774 99.0
WLSH2_k127_5361041_2 PFAM pfkB family carbohydrate kinase K00846 - 2.7.1.3 0.0000000000000000007824 88.0
WLSH2_k127_5371709_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.005e-296 917.0
WLSH2_k127_5371709_1 cytochrome d1, heme region K19345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 562.0
WLSH2_k127_5371709_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 308.0
WLSH2_k127_5371709_3 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000002797 217.0
WLSH2_k127_5371709_4 heme biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000008802 219.0
WLSH2_k127_5371709_5 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000001703 208.0
WLSH2_k127_5371709_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.0000000000000000000000000000000000004049 143.0
WLSH2_k127_5371709_7 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000002788 135.0
WLSH2_k127_5371709_8 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000000000004541 120.0
WLSH2_k127_5395717_0 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 430.0
WLSH2_k127_5395717_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000001852 134.0
WLSH2_k127_5395717_2 - - - - 0.00000000003591 69.0
WLSH2_k127_5424270_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 582.0
WLSH2_k127_5424270_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 350.0
WLSH2_k127_5424270_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 317.0
WLSH2_k127_5424270_3 Abortive infection bacteriophage resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 297.0
WLSH2_k127_5424270_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000832 80.0
WLSH2_k127_5466066_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 406.0
WLSH2_k127_5466066_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 349.0
WLSH2_k127_5466066_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000002549 105.0
WLSH2_k127_5471468_0 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 378.0
WLSH2_k127_5471468_1 SMART ATPase, AAA type, core - - - 0.000000000000000000000000000000000000000000000000000000001008 213.0
WLSH2_k127_5474307_0 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 300.0
WLSH2_k127_5474307_1 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000009594 223.0
WLSH2_k127_5474307_2 - - - - 0.00000000000000000000000000000004814 130.0
WLSH2_k127_547720_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 287.0
WLSH2_k127_547720_1 PFAM Outer membrane lipoprotein Slp K07285 - - 0.00000000000000000000000000000000000000000000000463 177.0
WLSH2_k127_5502968_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 321.0
WLSH2_k127_5502968_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000003173 153.0
WLSH2_k127_5502968_2 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000004219 127.0
WLSH2_k127_5523306_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 556.0
WLSH2_k127_5523306_1 Putative peptidoglycan binding domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 409.0
WLSH2_k127_5523306_2 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 254.0
WLSH2_k127_5523306_3 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000378 190.0
WLSH2_k127_5537853_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 353.0
WLSH2_k127_5537853_1 Glucose-regulated metallo-peptidase M90 K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009797 279.0
WLSH2_k127_5537853_2 Transposase IS200 like K07491 - - 0.0000000000000005283 78.0
WLSH2_k127_5537853_3 phosphoprotein phosphatase activity - - - 0.000000000000001611 87.0
WLSH2_k127_5556898_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
WLSH2_k127_5556898_1 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000776 211.0
WLSH2_k127_5556898_2 - - - - 0.0000000000002302 79.0
WLSH2_k127_5576496_0 DNA helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 575.0
WLSH2_k127_5576496_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000002729 158.0
WLSH2_k127_5577252_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 488.0
WLSH2_k127_5577252_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000001703 233.0
WLSH2_k127_5577252_10 - - - - 0.00000195 59.0
WLSH2_k127_5577252_2 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000006777 197.0
WLSH2_k127_5577252_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000001129 185.0
WLSH2_k127_5577252_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000002261 178.0
WLSH2_k127_5577252_6 ethyl tert-butyl ether degradation - - - 0.000000000000000000000000000000000000000004081 160.0
WLSH2_k127_5577252_7 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000004076 149.0
WLSH2_k127_5577252_8 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001816 104.0
WLSH2_k127_5577252_9 Transcriptional regulator - - - 0.0000000000000005708 81.0
WLSH2_k127_5633254_0 PFAM Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 416.0
WLSH2_k127_5633254_1 PFAM Lipocalin family protein K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000419 244.0
WLSH2_k127_5633254_2 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000000000002797 196.0
WLSH2_k127_5633254_3 Tim44 - - - 0.0000000000000000000000000000000000000000000000000716 183.0
WLSH2_k127_5633254_4 - - - - 0.0000000002417 68.0
WLSH2_k127_564590_0 Chromate transporter K07240 - - 2.306e-206 653.0
WLSH2_k127_564590_1 DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000006686 103.0
WLSH2_k127_564590_2 Domain of unknown function (DUF4282) - - - 0.00000000000000000007688 93.0
WLSH2_k127_5663074_0 Belongs to the NifD NifK NifE NifN family K02587 - - 5.669e-222 692.0
WLSH2_k127_5663074_1 Nitrogenase component 1 type Oxidoreductase K02592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 578.0
WLSH2_k127_5663074_2 Nitrogen fixation protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002697 226.0
WLSH2_k127_5663074_3 Pfam Dinitrogenase iron-molybdenum cofactor K02596 - - 0.0000000000000000000000000000000000000000009014 163.0
WLSH2_k127_5663074_4 Rop-like - - - 0.000000000000000000000008633 101.0
WLSH2_k127_5681501_0 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1216.0
WLSH2_k127_5689246_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 4.317e-236 737.0
WLSH2_k127_5689246_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 330.0
WLSH2_k127_5689246_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000001127 181.0
WLSH2_k127_5729516_0 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 497.0
WLSH2_k127_5729516_1 Peptidase family U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 490.0
WLSH2_k127_5729516_2 radical SAM protein K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 455.0
WLSH2_k127_5729516_3 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000587 280.0
WLSH2_k127_5729516_4 Peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
WLSH2_k127_5729516_5 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000001974 213.0
WLSH2_k127_5764158_0 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000003952 138.0
WLSH2_k127_5764158_1 Heavy-metal-associated domain K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000007346 127.0
WLSH2_k127_5764158_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000009199 63.0
WLSH2_k127_5826093_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 367.0
WLSH2_k127_5826093_1 Hint domain - - - 0.00000000000000000000000000000000000000000000000001053 191.0
WLSH2_k127_5826093_2 Protein of unknown function (DUF2452) - - - 0.000000000000000000000000000000000000000000002128 169.0
WLSH2_k127_5834062_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.19e-257 821.0
WLSH2_k127_5834062_1 double-strand break repair protein AddB K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000006802 231.0
WLSH2_k127_5843327_0 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 443.0
WLSH2_k127_5843327_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 379.0
WLSH2_k127_5874181_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 509.0
WLSH2_k127_5885703_0 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 289.0
WLSH2_k127_5885703_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000008203 232.0
WLSH2_k127_5885703_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0033554,GO:0034353,GO:0034641,GO:0034655,GO:0043167,GO:0043169,GO:0043170,GO:0043487,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0045935,GO:0046483,GO:0046700,GO:0046872,GO:0048518,GO:0048519,GO:0048522,GO:0050779,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000009024 142.0
WLSH2_k127_591184_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005626 231.0
WLSH2_k127_591184_1 Helix-turn-helix XRE-family like proteins K18831 - - 0.00000000000000000000000000000000000000000000000000000008247 200.0
WLSH2_k127_591184_2 protein conserved in bacteria K19166 - - 0.000000000000000000000000000000000000000000000003883 181.0
WLSH2_k127_591184_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000001471 178.0
WLSH2_k127_591184_4 - - - - 0.000000000000000000000008473 103.0
WLSH2_k127_595977_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 8.985e-220 685.0
WLSH2_k127_595977_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 519.0
WLSH2_k127_595977_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000002716 263.0
WLSH2_k127_595977_3 Tfp pilus assembly protein FimV K08086 - - 0.000000000000000000000000000001568 129.0
WLSH2_k127_5959871_0 CoA-substrate-specific enzyme activase - - - 0.0 1520.0
WLSH2_k127_5959871_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001597 244.0
WLSH2_k127_5968040_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 576.0
WLSH2_k127_5968040_1 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 331.0
WLSH2_k127_5968040_2 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 302.0
WLSH2_k127_5968040_3 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000005385 264.0
WLSH2_k127_5968040_4 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.000000000000000000000000000000000000000000000000000000000000000000001763 239.0
WLSH2_k127_5968040_5 Alkyl hydroperoxide reductase - - - 0.0000000000000005216 78.0
WLSH2_k127_6001397_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003016 291.0
WLSH2_k127_6001397_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000008007 121.0
WLSH2_k127_6001397_2 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000002795 94.0
WLSH2_k127_6037655_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 458.0
WLSH2_k127_6037655_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 377.0
WLSH2_k127_6037655_2 Molybdate ABC transporter K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 335.0
WLSH2_k127_6037655_3 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009406 273.0
WLSH2_k127_6037655_4 Protein of unknown function (DUF1207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004362 265.0
WLSH2_k127_6037655_5 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000001238 183.0
WLSH2_k127_6037655_6 - - - - 0.0000000000000000000008381 95.0
WLSH2_k127_6037655_8 FOG HPt domain K20976 - - 0.00000000522 61.0
WLSH2_k127_6041411_0 Hydrolase of alkaline phosphatase superfamily K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 528.0
WLSH2_k127_6041411_1 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 305.0
WLSH2_k127_6041411_2 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000008023 255.0
WLSH2_k127_6041411_3 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000000000000000000002938 222.0
WLSH2_k127_6069138_0 Belongs to the ompA family K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001252 274.0
WLSH2_k127_6069138_1 Involved in the tonB-independent uptake of proteins K01406,K01771,K03641 - 3.4.24.40,4.6.1.13 0.000000000000000000001578 111.0
WLSH2_k127_6069138_2 Carbohydrate binding module (family 6) - - - 0.0000134 59.0
WLSH2_k127_6079003_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 552.0
WLSH2_k127_6079003_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 552.0
WLSH2_k127_6079003_2 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 544.0
WLSH2_k127_6079003_3 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 487.0
WLSH2_k127_6079003_4 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008387 278.0
WLSH2_k127_6079003_5 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 263.0
WLSH2_k127_6079003_6 - - - - 0.00000000000000000000000000000000000000000005154 163.0
WLSH2_k127_6079003_7 D12 class N6 adenine-specific DNA methyltransferase K06223 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006281,GO:0006298,GO:0006304,GO:0006305,GO:0006306,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009007,GO:0009008,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0022402,GO:0032259,GO:0032775,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043412,GO:0043414,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044728,GO:0044786,GO:0044787,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901576,GO:1901681,GO:1902292,GO:1902328,GO:1904047 2.1.1.72 0.000000000000000000001167 102.0
WLSH2_k127_6104079_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 478.0
WLSH2_k127_6104079_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000001653 130.0
WLSH2_k127_6124781_0 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 565.0
WLSH2_k127_6124781_1 ATPase, AAA K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 339.0
WLSH2_k127_6124781_10 Glutaredoxin - - - 0.00000000000000000003331 93.0
WLSH2_k127_6124781_11 - - - - 0.00000000001873 69.0
WLSH2_k127_6124781_2 Belongs to the HAD-like hydrolase superfamily K02566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 316.0
WLSH2_k127_6124781_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 298.0
WLSH2_k127_6124781_4 - - - - 0.000000000000000000000000000000000000000000000000000009466 199.0
WLSH2_k127_6124781_5 Belongs to the Nudix hydrolase family K01518 - 3.6.1.17 0.000000000000000000000000000000000000000001424 162.0
WLSH2_k127_6124781_6 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000000000006665 142.0
WLSH2_k127_6124781_7 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000000000008711 126.0
WLSH2_k127_6124781_8 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000001367 124.0
WLSH2_k127_6124781_9 PQ loop repeat K15383 - - 0.00000000000000000000000008996 110.0
WLSH2_k127_613214_0 pteridine-dependent deoxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 375.0
WLSH2_k127_613214_1 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 347.0
WLSH2_k127_613214_2 MltA-interacting protein MipA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 308.0
WLSH2_k127_613214_3 Phosphate acyltransferases - - - 0.0000000000005246 72.0
WLSH2_k127_6145977_0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding K07689 - - 0.0000000000000000000000000000000000000000000000000000000000006402 222.0
WLSH2_k127_6145977_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000001286 198.0
WLSH2_k127_6145977_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03776 - - 0.000000000000000000000000000000000000000000000003621 179.0
WLSH2_k127_6176007_0 chondroitin AC lyase activity K00694,K01210,K03292 - 2.4.1.12,3.2.1.58 0.0 1047.0
WLSH2_k127_6176007_1 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 399.0
WLSH2_k127_6176007_2 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000008091 253.0
WLSH2_k127_6176007_3 beta (1-6) glucans synthase - - - 0.00000000493 62.0
WLSH2_k127_6176007_4 - - - - 0.0002214 55.0
WLSH2_k127_6178287_0 drug resistance transporter Bcr CflA subfamily K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 436.0
WLSH2_k127_6178287_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 329.0
WLSH2_k127_6178287_2 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 318.0
WLSH2_k127_6189790_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000001565 257.0
WLSH2_k127_6189790_1 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002286 253.0
WLSH2_k127_6189790_2 peptidoglycan biosynthetic process K03980 - - 0.000000000000000000000000000000000002063 156.0
WLSH2_k127_6189790_3 O-Antigen ligase - - - 0.0000000000000000000000003211 119.0
WLSH2_k127_6189790_4 Zinc-finger domain - - - 0.000000000000000001022 90.0
WLSH2_k127_6189790_5 - - - - 0.0001546 46.0
WLSH2_k127_6211572_0 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 517.0
WLSH2_k127_6211572_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 512.0
WLSH2_k127_6211572_2 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000001281 217.0
WLSH2_k127_6211572_3 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000003531 134.0
WLSH2_k127_6228134_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0 1433.0
WLSH2_k127_6228134_1 membrane protein domain - - - 0.0000000000000000000000000000000000003033 145.0
WLSH2_k127_6299793_0 PFAM ABC-1 domain protein K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 604.0
WLSH2_k127_6299793_1 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 449.0
WLSH2_k127_6302230_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 301.0
WLSH2_k127_6330211_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 314.0
WLSH2_k127_6330211_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000007966 214.0
WLSH2_k127_6330211_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18901 - - 0.00000000000000000000000000000000000000000003183 171.0
WLSH2_k127_6330211_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000001585 160.0
WLSH2_k127_6330211_4 acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000001319 109.0
WLSH2_k127_6337101_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 428.0
WLSH2_k127_6337101_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 384.0
WLSH2_k127_6337101_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001109 281.0
WLSH2_k127_6337101_3 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000000000000001245 221.0
WLSH2_k127_6337101_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000003532 128.0
WLSH2_k127_635619_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 1.523e-199 630.0
WLSH2_k127_635619_1 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 366.0
WLSH2_k127_635619_2 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000006853 145.0
WLSH2_k127_635619_3 conserved protein - - - 0.0000000000000000000000004006 112.0
WLSH2_k127_635619_4 Domain of unknown function (DUF3817) - - - 0.000000000000000002744 89.0
WLSH2_k127_635619_5 Cysteine-rich CWC - - - 0.000004527 53.0
WLSH2_k127_635619_6 Fe-S-cluster oxidoreductase K06940 - - 0.0001682 46.0
WLSH2_k127_6406812_0 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000004214 147.0
WLSH2_k127_6406812_1 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000004779 129.0
WLSH2_k127_6406812_2 Rhomboid family - - - 0.0000000000000000000000000000003625 130.0
WLSH2_k127_6406812_3 N-Acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000104 131.0
WLSH2_k127_6410974_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 3.066e-307 949.0
WLSH2_k127_6410974_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 3.002e-203 651.0
WLSH2_k127_6410974_2 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000005175 160.0
WLSH2_k127_6410974_3 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000003698 128.0
WLSH2_k127_6410974_4 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000009367 96.0
WLSH2_k127_6424641_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 8.093e-221 690.0
WLSH2_k127_6424641_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 417.0
WLSH2_k127_6424641_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 339.0
WLSH2_k127_6424641_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000004212 220.0
WLSH2_k127_6424641_4 Acyltransferase - - - 0.000000000000000000004189 102.0
WLSH2_k127_6424641_5 - - - - 0.0000005097 53.0
WLSH2_k127_6448489_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 518.0
WLSH2_k127_6448489_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001153 279.0
WLSH2_k127_6448489_2 Hint domain - - - 0.00000000000000000000000000000000000000000007278 165.0
WLSH2_k127_6448489_3 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000000625 158.0
WLSH2_k127_6450020_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 449.0
WLSH2_k127_6450020_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 429.0
WLSH2_k127_6450020_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003083 278.0
WLSH2_k127_6450020_3 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000001329 257.0
WLSH2_k127_6450020_4 Belongs to the UPF0250 family - - - 0.00000000000000000000003997 103.0
WLSH2_k127_6490567_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 419.0
WLSH2_k127_6490567_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001362 284.0
WLSH2_k127_6490567_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008272 246.0
WLSH2_k127_6490567_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000002252 177.0
WLSH2_k127_6490567_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.0000000000001539 71.0
WLSH2_k127_6492930_0 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006139 272.0
WLSH2_k127_6492930_1 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000002211 158.0
WLSH2_k127_6492930_2 transcriptional regulator K03892 - - 0.00000000000000000000000000000000008323 142.0
WLSH2_k127_6492930_3 NLP P60 protein - - - 0.0000000000000000000000000000002749 127.0
WLSH2_k127_6492930_4 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000003135 73.0
WLSH2_k127_6492930_5 Receptor family ligand binding region K01999 - - 0.000213 46.0
WLSH2_k127_6516747_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 505.0
WLSH2_k127_6516747_1 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 497.0
WLSH2_k127_6516747_2 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000003188 191.0
WLSH2_k127_6516747_3 Rhodanese Homology Domain - - - 0.0000000000000000000000003062 121.0
WLSH2_k127_6516747_4 beta-lactamase activity K07126,K13582 - - 0.0003061 48.0
WLSH2_k127_6526135_0 Synthesizes selenophosphate from selenide and ATP K01008 GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 497.0
WLSH2_k127_6526135_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000002197 220.0
WLSH2_k127_6526135_2 COG0500 SAM-dependent methyltransferases - - - 0.0000001181 54.0
WLSH2_k127_6529950_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 5.63e-236 742.0
WLSH2_k127_6529950_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 555.0
WLSH2_k127_6529950_10 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000003256 91.0
WLSH2_k127_6529950_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 293.0
WLSH2_k127_6529950_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000004334 265.0
WLSH2_k127_6529950_4 Thioredoxin-like domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000005737 224.0
WLSH2_k127_6529950_5 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 - 0.0000000000000000000000000000000000000000000002702 171.0
WLSH2_k127_6529950_6 regulatory protein, arsR - - - 0.000000000000000000000000000000000000000000001557 166.0
WLSH2_k127_6529950_7 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000001599 149.0
WLSH2_k127_6529950_8 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000003265 117.0
WLSH2_k127_6529950_9 Protein of unknown function (DUF2892) - - - 0.00000000000000000000008492 100.0
WLSH2_k127_6531044_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 512.0
WLSH2_k127_6531044_1 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 302.0
WLSH2_k127_6531044_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000003108 198.0
WLSH2_k127_6531044_3 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000001112 184.0
WLSH2_k127_6531044_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000396 175.0
WLSH2_k127_6531044_5 - - - - 0.000000000000000000000000129 116.0
WLSH2_k127_6531044_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000009032 90.0
WLSH2_k127_6542667_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 613.0
WLSH2_k127_6542667_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 403.0
WLSH2_k127_6542667_2 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 305.0
WLSH2_k127_6542667_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
WLSH2_k127_6542667_4 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000003927 205.0
WLSH2_k127_6542667_5 - - - - 0.0000000000003516 76.0
WLSH2_k127_6543824_0 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 546.0
WLSH2_k127_6543824_1 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 314.0
WLSH2_k127_6543824_2 dehydratase - - - 0.000000000000000000000000000000000000000000000000005746 184.0
WLSH2_k127_6543824_3 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.00000000000000002355 94.0
WLSH2_k127_6550562_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.129e-295 916.0
WLSH2_k127_6550562_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000006677 199.0
WLSH2_k127_6550562_2 Oxidoreductase - - - 0.000005121 49.0
WLSH2_k127_6560244_0 DoxX - - - 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
WLSH2_k127_6560244_1 protein conserved in bacteria K09929 - - 0.00000000000000000000000000000000000000000000000000000004319 205.0
WLSH2_k127_6570322_0 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 603.0
WLSH2_k127_6570322_1 Histidine kinase K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 355.0
WLSH2_k127_6570322_10 - - - - 0.00000000004917 68.0
WLSH2_k127_6570322_2 response regulator receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 317.0
WLSH2_k127_6570322_3 deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002005 260.0
WLSH2_k127_6570322_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003198 228.0
WLSH2_k127_6570322_5 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000002864 213.0
WLSH2_k127_6570322_6 alpha-ribazole phosphatase activity K01834 GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009628,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036293,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.11 0.00000000000000000000000000000000000000000000000000001598 198.0
WLSH2_k127_6570322_7 Universal stress protein family - - - 0.000000000000000000000000000000000000000003537 160.0
WLSH2_k127_6570322_8 Glycine zipper 2TM domain - - - 0.000000000000000000000000000004595 127.0
WLSH2_k127_6570322_9 Acid phosphatase homologues - - - 0.00000000000000000000137 105.0
WLSH2_k127_6573646_0 TIGRFAM N-acetyl sugar amidotransferase - - - 1.909e-235 735.0
WLSH2_k127_6573646_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.473e-200 642.0
WLSH2_k127_6573646_2 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 369.0
WLSH2_k127_6573646_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 363.0
WLSH2_k127_6573646_4 UDP-N-acetylglucosamine 2-epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 359.0
WLSH2_k127_6573646_5 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001527 278.0
WLSH2_k127_6573646_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004492 252.0
WLSH2_k127_6573646_7 PFAM sugar transferase K03606 - - 0.00000000000000000000000000000000000000000000000000000001301 202.0
WLSH2_k127_6573646_8 Cytidylyltransferase K18431 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.82 0.00000000000000000000000000000000000000000000000000005035 195.0
WLSH2_k127_6573646_9 - - - - 0.000000000000000004997 93.0
WLSH2_k127_6607695_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1227.0
WLSH2_k127_6607695_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.148e-252 785.0
WLSH2_k127_6607695_2 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 6.359e-217 682.0
WLSH2_k127_6607695_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 572.0
WLSH2_k127_6607695_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 489.0
WLSH2_k127_6607695_5 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 460.0
WLSH2_k127_6607695_6 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000009743 164.0
WLSH2_k127_6607695_7 - - - - 0.00000000000001114 75.0
WLSH2_k127_6607695_8 T5orf172 - - - 0.00000000000396 74.0
WLSH2_k127_6626067_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 482.0
WLSH2_k127_6626067_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000003252 98.0
WLSH2_k127_6626067_2 Domain of unknown function (DUF4390) - - - 0.000000000000000000001198 100.0
WLSH2_k127_6667718_0 Type IX secretion system membrane protein PorP/SprF - - - 0.0000000000000000000000000000000000000000000000002989 193.0
WLSH2_k127_6691803_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 331.0
WLSH2_k127_6691803_1 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 306.0
WLSH2_k127_6691803_2 PhnA domain K06193 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 297.0
WLSH2_k127_6691803_3 membrane - - - 0.000000000000000000000000000000000003577 147.0
WLSH2_k127_6691803_4 PFAM Cold-shock K03704 - - 0.0000000000000000000000000000002428 123.0
WLSH2_k127_6709681_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 597.0
WLSH2_k127_6709681_1 HD-GYP domain - GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 362.0
WLSH2_k127_6715252_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 574.0
WLSH2_k127_6715252_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 462.0
WLSH2_k127_6715252_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 321.0
WLSH2_k127_6715252_3 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000009334 188.0
WLSH2_k127_6715252_4 Protein of unknown function (DUF2818) - - - 0.000000000000000000000000000000005825 130.0
WLSH2_k127_6715252_5 - - - - 0.000000000644 61.0
WLSH2_k127_6742524_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 547.0
WLSH2_k127_6742524_1 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 535.0
WLSH2_k127_6742524_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000256 243.0
WLSH2_k127_6742524_3 sulfur carrier activity K04085 - - 0.000000000000000000000000003224 113.0
WLSH2_k127_6743183_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 1.223e-216 678.0
WLSH2_k127_6743183_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 428.0
WLSH2_k127_6743183_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000001775 183.0
WLSH2_k127_6743183_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000003593 180.0
WLSH2_k127_6743183_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000008497 161.0
WLSH2_k127_6747608_0 Pfam Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000003745 160.0
WLSH2_k127_6747608_1 Belongs to the peptidase M48B family - - - 0.00001341 57.0
WLSH2_k127_6799299_0 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 3.929e-294 917.0
WLSH2_k127_6799299_1 (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 627.0
WLSH2_k127_6799299_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000007317 252.0
WLSH2_k127_6799299_3 PFAM globin K06886 - - 0.0000000000000000000000000000000000000000000000000000008576 194.0
WLSH2_k127_6799299_4 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000006429 190.0
WLSH2_k127_6799299_5 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000003148 175.0
WLSH2_k127_6799299_6 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000005626 160.0
WLSH2_k127_6799299_7 oligosaccharyl transferase activity - - - 0.00000000000000000000000000008717 124.0
WLSH2_k127_6799299_8 oligosaccharyl transferase activity - - - 0.00000000001837 71.0
WLSH2_k127_6799299_9 oligosaccharyl transferase activity - - - 0.0000001009 59.0
WLSH2_k127_6801144_0 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000001538 216.0
WLSH2_k127_6801144_1 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000001267 208.0
WLSH2_k127_6801144_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000001323 173.0
WLSH2_k127_6801144_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000002781 155.0
WLSH2_k127_6803330_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
WLSH2_k127_6803330_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 344.0
WLSH2_k127_6803330_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001645 274.0
WLSH2_k127_6803330_3 PFAM MucB RseB K03598 - - 0.00000000000000000000000000000000000000000000000000000000001634 218.0
WLSH2_k127_6803330_4 PFAM Positive regulator of sigma(E), RseC MucC K03803 - - 0.0000000000000000000000000001753 121.0
WLSH2_k127_6803330_5 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.00000000000000000002184 100.0
WLSH2_k127_6817817_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.926e-302 936.0
WLSH2_k127_6817817_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000001591 161.0
WLSH2_k127_6817817_2 Glutaredoxin-like domain (DUF836) - - - 0.000000000001577 75.0
WLSH2_k127_6877517_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1712.0
WLSH2_k127_6877517_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1006.0
WLSH2_k127_6877517_2 Belongs to the CarA family K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 2.687e-194 611.0
WLSH2_k127_6877517_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 586.0
WLSH2_k127_6877517_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 344.0
WLSH2_k127_6877517_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 291.0
WLSH2_k127_6877517_6 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003277 280.0
WLSH2_k127_6877517_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000002135 238.0
WLSH2_k127_6877517_8 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000003473 117.0
WLSH2_k127_6877517_9 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.0000000000000000000000008447 106.0
WLSH2_k127_6896912_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.562e-319 990.0
WLSH2_k127_6896912_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.575e-199 630.0
WLSH2_k127_6896912_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001089 74.0
WLSH2_k127_6896912_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 577.0
WLSH2_k127_6896912_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 530.0
WLSH2_k127_6896912_4 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 497.0
WLSH2_k127_6896912_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0003674,GO:0003824,GO:0003887,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022616,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 443.0
WLSH2_k127_6896912_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001918 269.0
WLSH2_k127_6896912_7 organic phosphonate transport K02044 - - 0.00000000000000000000000000000000000009929 153.0
WLSH2_k127_6896912_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000000000000004057 125.0
WLSH2_k127_6896912_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000002061 115.0
WLSH2_k127_6917606_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 4.905e-288 900.0
WLSH2_k127_6921638_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035597,GO:0035600,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 541.0
WLSH2_k127_6921638_1 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 475.0
WLSH2_k127_6921638_2 PFAM CBS domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 341.0
WLSH2_k127_6921638_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 306.0
WLSH2_k127_6921638_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000001269 203.0
WLSH2_k127_6938663_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 546.0
WLSH2_k127_6938663_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000001549 216.0
WLSH2_k127_6938663_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.000000000000003695 76.0
WLSH2_k127_6974016_0 von Willebrand factor (vWF) type A domain K02448 - - 2.293e-197 628.0
WLSH2_k127_6974016_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 431.0
WLSH2_k127_6987332_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1081.0
WLSH2_k127_6987332_1 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001305 260.0
WLSH2_k127_6987332_3 type I secretion outer membrane protein, TolC K12340 - - 0.0009163 43.0
WLSH2_k127_7061923_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07641,K07711 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031667,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 462.0
WLSH2_k127_7061923_1 Transcriptional regulatory protein, C terminal K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001552 262.0
WLSH2_k127_7061923_2 Glutathione S-transferase - - - 0.0000000008884 59.0
WLSH2_k127_7080713_0 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 446.0
WLSH2_k127_7080713_1 activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001025 280.0
WLSH2_k127_7080713_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003527 275.0
WLSH2_k127_7108464_0 - - - - 2.208e-219 683.0
WLSH2_k127_7108464_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000005278 143.0
WLSH2_k127_7108464_2 general secretion pathway protein - - - 0.00003259 46.0
WLSH2_k127_7121733_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.293e-281 882.0
WLSH2_k127_7121733_1 Bile acid sodium symporter K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 369.0
WLSH2_k127_7121733_2 Hint domain - - - 0.00000000000000000000000000000000000000000000000203 184.0
WLSH2_k127_7121733_3 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000005207 144.0
WLSH2_k127_7121733_4 This gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.000000000000007323 76.0
WLSH2_k127_7131963_0 Diguanylate cyclase - - - 5.868e-213 695.0
WLSH2_k127_7131963_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000000000000000002667 157.0
WLSH2_k127_7131963_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000006916 108.0
WLSH2_k127_7131963_3 Belongs to the ClpA ClpB family K03694 - - 0.00000000002306 65.0
WLSH2_k127_7146651_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 261.0
WLSH2_k127_7146651_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006766 235.0
WLSH2_k127_7163491_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000002721 145.0
WLSH2_k127_7184645_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1055.0
WLSH2_k127_7184645_1 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.482e-202 640.0
WLSH2_k127_7184645_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 431.0
WLSH2_k127_7184645_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 361.0
WLSH2_k127_7184645_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 368.0
WLSH2_k127_7184645_5 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 332.0
WLSH2_k127_7184645_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 326.0
WLSH2_k127_7184645_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 251.0
WLSH2_k127_7184645_8 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000004769 94.0
WLSH2_k127_7185442_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.131e-274 851.0
WLSH2_k127_7185442_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.505e-269 834.0
WLSH2_k127_7185442_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 329.0
WLSH2_k127_7185442_3 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005147 274.0
WLSH2_k127_7185442_4 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000738 175.0
WLSH2_k127_7185442_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000003532 137.0
WLSH2_k127_7185442_6 Cytochrome c554 and c-prime - - - 0.000000000000000003173 92.0
WLSH2_k127_7185442_7 5'-nucleotidase - - - 0.000000000000000008761 92.0
WLSH2_k127_719790_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 401.0
WLSH2_k127_719790_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000001796 62.0
WLSH2_k127_7222837_0 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 287.0
WLSH2_k127_7222837_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000001884 208.0
WLSH2_k127_7222837_2 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000008632 183.0
WLSH2_k127_7222837_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000002886 183.0
WLSH2_k127_7222837_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000222 141.0
WLSH2_k127_7222837_5 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000847 84.0
WLSH2_k127_726628_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.011e-237 746.0
WLSH2_k127_726628_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 309.0
WLSH2_k127_726628_2 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000002307 234.0
WLSH2_k127_726628_3 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000009236 181.0
WLSH2_k127_7273060_0 associated with various cellular activities - - - 2.219e-194 610.0
WLSH2_k127_7273060_1 Putative metallopeptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 402.0
WLSH2_k127_7273060_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000001215 204.0
WLSH2_k127_7273060_3 membrane organization K20543 - - 0.0000000000000000000000000000000000000000000000000009295 199.0
WLSH2_k127_7333054_0 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000008133 140.0
WLSH2_k127_7333054_1 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000004667 113.0
WLSH2_k127_7333054_2 Thioredoxin - - - 0.00000000000000000003046 94.0
WLSH2_k127_7337751_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001087 285.0
WLSH2_k127_7337751_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003003 284.0
WLSH2_k127_7362993_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 5.374e-259 803.0
WLSH2_k127_7362993_1 nucleoside-diphosphate sugar epimerases - - - 2.467e-207 664.0
WLSH2_k127_7362993_2 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 610.0
WLSH2_k127_7362993_3 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 562.0
WLSH2_k127_7362993_4 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000008042 207.0
WLSH2_k127_7362993_5 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000008459 160.0
WLSH2_k127_7362993_6 Lipid A core - O-antigen ligase and K02847 - - 0.0000000000000000000000000002306 130.0
WLSH2_k127_7362993_7 UDP-N-acetylglucosamine 2-epimerase - - - 0.000000002091 60.0
WLSH2_k127_7367293_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 583.0
WLSH2_k127_7367293_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 505.0
WLSH2_k127_7367293_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 419.0
WLSH2_k127_7367293_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000001038 108.0
WLSH2_k127_7377231_0 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 300.0
WLSH2_k127_7377231_1 PFAM Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 302.0
WLSH2_k127_7377231_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000907 274.0
WLSH2_k127_7377231_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000008428 176.0
WLSH2_k127_7377231_4 - - - - 0.0000000000000000000000001655 108.0
WLSH2_k127_7426486_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 5.018e-217 689.0
WLSH2_k127_7426486_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 580.0
WLSH2_k127_7426486_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 451.0
WLSH2_k127_7426486_3 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000005347 144.0
WLSH2_k127_7445219_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.15e-242 759.0
WLSH2_k127_7445219_1 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000003641 215.0
WLSH2_k127_74640_0 transmembrane transport K02035,K13893 - - 2.471e-234 746.0
WLSH2_k127_74640_1 ABC transporter permease protein K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 531.0
WLSH2_k127_74640_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 525.0
WLSH2_k127_74640_3 ABC transporter permease protein K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 516.0
WLSH2_k127_74640_4 peptidyl-prolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 446.0
WLSH2_k127_74640_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000002047 136.0
WLSH2_k127_7466904_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.759e-238 750.0
WLSH2_k127_7466904_1 - - - - 0.000000000000000000000000000000000000009271 149.0
WLSH2_k127_7466904_2 - - - - 0.00000000000000001823 88.0
WLSH2_k127_7611635_0 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 348.0
WLSH2_k127_7611635_1 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000006122 126.0
WLSH2_k127_7611635_2 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000002622 120.0
WLSH2_k127_76197_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.986e-220 689.0
WLSH2_k127_76197_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 537.0
WLSH2_k127_76197_2 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 366.0
WLSH2_k127_7629020_0 (GGDEF) domain K21024 - 3.1.4.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 444.0
WLSH2_k127_7629020_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000000002958 64.0
WLSH2_k127_7644448_0 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 601.0
WLSH2_k127_7644448_1 Hydrogenase maturation protease - - - 0.00000000000000000000000004929 119.0
WLSH2_k127_7644448_2 Coenzyme F420-reducing hydrogenase, gamma subunit - - - 0.0000000000002467 70.0
WLSH2_k127_7649630_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 562.0
WLSH2_k127_7649630_1 PFAM FAD linked oxidase domain protein K03777 - 1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 366.0
WLSH2_k127_7649630_2 His Kinase A (phosphoacceptor) domain - - - 0.000000001594 59.0
WLSH2_k127_7682971_0 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002366 288.0
WLSH2_k127_7682971_1 Permease K07091 - - 0.000000000000000000000000000000000000000000000000001215 192.0
WLSH2_k127_7682971_2 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000001414 118.0
WLSH2_k127_771126_0 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 8.34e-264 822.0
WLSH2_k127_771126_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 611.0
WLSH2_k127_771126_2 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006537 561.0
WLSH2_k127_771126_3 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 329.0
WLSH2_k127_771126_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007827 264.0
WLSH2_k127_771126_5 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.0000000000000000000004948 98.0
WLSH2_k127_7715570_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079,K22110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 479.0
WLSH2_k127_7715570_1 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
WLSH2_k127_7715570_2 protease with the C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 387.0
WLSH2_k127_7715570_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 344.0
WLSH2_k127_7715570_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 345.0
WLSH2_k127_7715570_5 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
WLSH2_k127_7715570_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000001032 137.0
WLSH2_k127_7715570_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000002363 128.0
WLSH2_k127_7715570_8 - - - - 0.00000000000000000000000000212 119.0
WLSH2_k127_7715570_9 - - - - 0.000000000000000000000009214 105.0
WLSH2_k127_7766757_0 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 290.0
WLSH2_k127_7766757_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 281.0
WLSH2_k127_7766757_2 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000001083 209.0
WLSH2_k127_7785278_0 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 486.0
WLSH2_k127_7785278_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005813 274.0
WLSH2_k127_7785278_2 Sh3 type 3 domain protein - - - 0.0000000000002878 77.0
WLSH2_k127_7792858_0 Cytochrome c oxidase subunit K00376 - 1.7.2.4 0.0 1064.0
WLSH2_k127_7792858_1 FMN-binding domain protein K19339 - - 0.0 1030.0
WLSH2_k127_7792858_2 Periplasmic copper-binding K07218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 609.0
WLSH2_k127_7792858_3 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 424.0
WLSH2_k127_7792858_4 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 401.0
WLSH2_k127_7792858_5 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 361.0
WLSH2_k127_7792858_6 Response regulator receiver K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000001194 226.0
WLSH2_k127_7792858_7 NosL family K19342 - - 0.00000000000000000000000000000000000000000000000000000000000001505 223.0
WLSH2_k127_7792858_8 - - - - 0.0000000000000000000000000000000001501 136.0
WLSH2_k127_7792858_9 - - - - 0.0000000000000000007782 89.0
WLSH2_k127_7803054_0 PFAM von Willebrand factor type A - - - 0.0 1207.0
WLSH2_k127_7803054_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 2.181e-301 929.0
WLSH2_k127_7803054_2 PFAM AAA domain (dynein-related subfamily) K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 490.0
WLSH2_k127_7803054_3 ribulose bisphosphate carboxylase, small K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000006528 237.0
WLSH2_k127_7808980_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.081e-293 919.0
WLSH2_k127_7808980_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 9.25e-217 680.0
WLSH2_k127_7808980_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 500.0
WLSH2_k127_7808980_3 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 389.0
WLSH2_k127_7808980_4 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 333.0
WLSH2_k127_7808980_5 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000003052 51.0
WLSH2_k127_7813768_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 496.0
WLSH2_k127_7813768_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 375.0
WLSH2_k127_7813768_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007117 272.0
WLSH2_k127_7813768_3 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000408 59.0
WLSH2_k127_7813768_4 - - - - 0.0006094 51.0
WLSH2_k127_784646_0 - K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000001061 164.0
WLSH2_k127_784646_1 FG-GAP repeat - - - 0.000000000000000000000000000000000000002167 150.0
WLSH2_k127_784646_2 P-type ATPase K17686 - 3.6.3.54 0.000000000000006748 76.0
WLSH2_k127_7852635_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 530.0
WLSH2_k127_7852635_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 452.0
WLSH2_k127_7852635_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 349.0
WLSH2_k127_7852635_3 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 332.0
WLSH2_k127_7852635_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
WLSH2_k127_7852635_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000001626 152.0
WLSH2_k127_7892628_0 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 357.0
WLSH2_k127_7892628_1 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001919 267.0
WLSH2_k127_7892628_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000002681 239.0
WLSH2_k127_7892628_3 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000000005646 224.0
WLSH2_k127_7892628_4 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000001026 218.0
WLSH2_k127_7892628_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000002898 166.0
WLSH2_k127_7911715_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 527.0
WLSH2_k127_7911715_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 320.0
WLSH2_k127_7911715_2 CHASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002014 255.0
WLSH2_k127_7921577_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 585.0
WLSH2_k127_7921577_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008936 344.0
WLSH2_k127_7921577_2 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000001586 151.0
WLSH2_k127_7921577_3 Phosphotransferase System K11189 - - 0.000000000000000000000007648 109.0
WLSH2_k127_7921577_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00001035 48.0
WLSH2_k127_7962712_0 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000001253 197.0
WLSH2_k127_7962712_1 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000007983 171.0
WLSH2_k127_7962712_2 Bacterial DNA-binding protein - - - 0.000000000000000000000000000038 122.0
WLSH2_k127_7962712_3 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000003323 93.0
WLSH2_k127_8036614_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 522.0
WLSH2_k127_8036614_1 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 511.0
WLSH2_k127_8036614_2 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000009967 119.0
WLSH2_k127_8036614_3 Phosphopantetheine attachment site K02078 - - 0.0000000000001654 76.0
WLSH2_k127_8036614_4 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.0003248 47.0
WLSH2_k127_8039550_0 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000637 263.0
WLSH2_k127_8039550_1 Cytochrome b561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000002145 225.0
WLSH2_k127_8039550_2 CAAX protease self-immunity K07052 - - 0.0000000000003481 78.0
WLSH2_k127_8039550_3 Belongs to the pirin family K06911 - - 0.0000000001804 61.0
WLSH2_k127_8063866_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 4.467e-267 838.0
WLSH2_k127_8063866_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000001119 128.0
WLSH2_k127_8083161_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007981 569.0
WLSH2_k127_8083161_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 552.0
WLSH2_k127_8083161_2 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 418.0
WLSH2_k127_8083161_3 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 392.0
WLSH2_k127_8083161_4 Bacterial lipid A biosynthesis acyltransferase K02560 - 2.3.1.243 0.000000000000000000000000000000000000000000000000000000000000000000000000002556 265.0
WLSH2_k127_8083161_5 Alanine-zipper, major outer membrane lipoprotein - - - 0.0000000000000000003475 90.0
WLSH2_k127_8083161_6 COG1943 Transposase and inactivated derivatives K07491 - - 0.000108 48.0
WLSH2_k127_8084042_0 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 5.892e-306 957.0
WLSH2_k127_8092480_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 490.0
WLSH2_k127_8092480_1 type I restriction-modification system K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000003083 214.0
WLSH2_k127_8092480_2 TIGRFAM conserved - - - 0.00000000000000000000000007752 119.0
WLSH2_k127_8092480_3 alanine dehydrogenase K00259 - 1.4.1.1 0.0000000000000004111 79.0
WLSH2_k127_8114488_0 Sodium/hydrogen exchanger family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 599.0
WLSH2_k127_8114488_1 - - - - 0.00000000000000000000000000000000000005858 156.0
WLSH2_k127_8118886_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 418.0
WLSH2_k127_8118886_1 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 326.0
WLSH2_k127_8118886_2 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 300.0
WLSH2_k127_8118886_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000139 176.0
WLSH2_k127_8118886_4 Domain of unknown function (DUF4266) - - - 0.0000000000000000000137 93.0
WLSH2_k127_8121707_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0031249,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0 1025.0
WLSH2_k127_8121707_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 392.0
WLSH2_k127_8121707_2 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 309.0
WLSH2_k127_8121707_3 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000008222 102.0
WLSH2_k127_8121707_4 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000008007 64.0
WLSH2_k127_8142812_0 general secretion pathway protein D K02453 - - 1.096e-195 632.0
WLSH2_k127_8142812_1 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 602.0
WLSH2_k127_8142812_2 Type II secretion system protein C - - - 0.00000000000000000000000000000000000008299 153.0
WLSH2_k127_8142812_3 ABC-2 family transporter protein - - - 0.00000000000000000000000003726 112.0
WLSH2_k127_8142812_4 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.0000000000000002588 81.0
WLSH2_k127_8148007_0 Heat shock 70 kDa protein K04043 - - 0.0 1020.0
WLSH2_k127_8148007_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 572.0
WLSH2_k127_8148007_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 435.0
WLSH2_k127_8148007_3 May be involved in recombinational repair of damaged DNA K03631 GO:0000724,GO:0000725,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 378.0
WLSH2_k127_8148007_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 316.0
WLSH2_k127_8148007_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000002014 191.0
WLSH2_k127_8153133_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 589.0
WLSH2_k127_8153133_1 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000002014 148.0
WLSH2_k127_8153133_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000212 108.0
WLSH2_k127_8153133_3 - - - - 0.0000000000000000000000001517 118.0
WLSH2_k127_8153133_4 Cytochrome c - - - 0.000000000000000007407 91.0
WLSH2_k127_8157393_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 1.358e-232 726.0
WLSH2_k127_8157393_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 526.0
WLSH2_k127_8157393_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 440.0
WLSH2_k127_8157393_3 Gram-negative porin - - - 0.0000000000000000000000000000000005899 146.0
WLSH2_k127_8157642_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 6.435e-256 811.0
WLSH2_k127_8157642_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 340.0
WLSH2_k127_8157642_2 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 298.0
WLSH2_k127_8157642_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000003179 161.0
WLSH2_k127_8157642_4 - - - - 0.000000000000000000000000000000003515 143.0
WLSH2_k127_8157642_5 NHL repeat containing protein - - - 0.0000000000000001344 91.0
WLSH2_k127_8180442_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.024e-248 788.0
WLSH2_k127_8180442_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 362.0
WLSH2_k127_8180442_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 356.0
WLSH2_k127_8180442_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000003438 235.0
WLSH2_k127_8180442_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000104 229.0
WLSH2_k127_8180442_5 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000141 151.0
WLSH2_k127_8187102_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 317.0
WLSH2_k127_8187102_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001874 275.0
WLSH2_k127_8187102_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000008218 224.0
WLSH2_k127_819352_0 AcrB/AcrD/AcrF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 527.0
WLSH2_k127_8205238_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1149.0
WLSH2_k127_8216286_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 555.0
WLSH2_k127_8216286_1 Domain of unknown function(DUF2779) - - - 0.0000000000000000000000000000000000988 137.0
WLSH2_k127_8216286_2 Domain of unknown function(DUF2779) - - - 0.000000000000001145 78.0
WLSH2_k127_8221827_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 479.0
WLSH2_k127_8221827_1 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000006545 216.0
WLSH2_k127_8221827_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000001643 109.0
WLSH2_k127_8221827_3 Protein of unknown function (DUF3301) - - - 0.0000000000005771 73.0
WLSH2_k127_8222276_0 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 448.0
WLSH2_k127_8222276_1 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002148 252.0
WLSH2_k127_8222276_2 cytochrome - - - 0.00002196 47.0
WLSH2_k127_8222276_3 Major Facilitator Superfamily - - - 0.00004733 48.0
WLSH2_k127_8241116_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 357.0
WLSH2_k127_8241116_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000004585 187.0
WLSH2_k127_8241116_2 transcriptional regulator - - - 0.00000000000000000000000000000000002644 141.0
WLSH2_k127_8262172_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 420.0
WLSH2_k127_8263371_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 451.0
WLSH2_k127_8263371_1 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000003799 144.0
WLSH2_k127_8263371_2 alginic acid biosynthetic process - - - 0.0000000000000000000000002356 120.0
WLSH2_k127_8264663_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 6.469e-202 633.0
WLSH2_k127_8264663_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 510.0
WLSH2_k127_8264663_2 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000133 166.0
WLSH2_k127_8272352_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 486.0
WLSH2_k127_8272352_1 protein conserved in archaea - - - 0.000000000000000000000000000000000000000000000000007318 188.0
WLSH2_k127_8275402_0 phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 308.0
WLSH2_k127_8275402_1 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002057 250.0
WLSH2_k127_8275402_2 Responsible for synthesis of pseudouridine from uracil K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000004684 229.0
WLSH2_k127_8275402_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000008726 53.0
WLSH2_k127_8279644_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 570.0
WLSH2_k127_8279644_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002431 255.0
WLSH2_k127_8279644_2 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000008342 192.0
WLSH2_k127_8279644_3 LigT like Phosphoesterase - - - 0.0000000000000000000000000000000112 134.0
WLSH2_k127_8279644_4 Modulates RecA activity K03565 - - 0.00000000000000000000000000003905 121.0
WLSH2_k127_8285230_0 Molecular chaperone. Has ATPase activity K04079 - - 1.034e-297 925.0
WLSH2_k127_8285230_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 507.0
WLSH2_k127_8285230_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 442.0
WLSH2_k127_8285230_3 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 426.0
WLSH2_k127_8288814_0 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 597.0
WLSH2_k127_8288814_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000423 162.0
WLSH2_k127_8304700_0 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 405.0
WLSH2_k127_8304700_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000002082 170.0
WLSH2_k127_8304700_2 Domain of unknown function (DUF4156) - - - 0.0000001544 53.0
WLSH2_k127_8320586_0 response regulator receiver K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007523 502.0
WLSH2_k127_8320586_1 Histidine kinase K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 412.0
WLSH2_k127_8320586_2 - K06950 - - 0.00000000009253 65.0
WLSH2_k127_8320586_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000006255 53.0
WLSH2_k127_8324158_0 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 576.0
WLSH2_k127_8324158_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 429.0
WLSH2_k127_8324158_2 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000004194 232.0
WLSH2_k127_8324158_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000005713 229.0
WLSH2_k127_8349953_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 7.288e-210 659.0
WLSH2_k127_8349953_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 347.0
WLSH2_k127_8349953_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 350.0
WLSH2_k127_8349953_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002757 263.0
WLSH2_k127_8349953_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000002754 262.0
WLSH2_k127_8349953_5 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000001107 86.0
WLSH2_k127_8355290_0 Cytochrome D1 heme domain - - - 6.729e-225 708.0
WLSH2_k127_8355290_1 Diguanylate cyclase - - - 6.711e-199 658.0
WLSH2_k127_8355290_2 radical SAM protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 608.0
WLSH2_k127_8355290_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 360.0
WLSH2_k127_8355290_4 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000000001955 189.0
WLSH2_k127_8355290_5 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000008005 185.0
WLSH2_k127_8355290_6 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000001552 178.0
WLSH2_k127_8376989_0 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000000000000005937 163.0
WLSH2_k127_8376989_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000002141 146.0
WLSH2_k127_8376989_2 protein acetylation - - - 0.000000000000000000000000000000905 128.0
WLSH2_k127_8398219_0 Membrane - - - 9.776e-226 711.0
WLSH2_k127_8398219_1 Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 460.0
WLSH2_k127_8398219_2 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000001476 57.0
WLSH2_k127_8456436_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 310.0
WLSH2_k127_8456436_1 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007754 272.0
WLSH2_k127_8456436_2 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001804 261.0
WLSH2_k127_8456436_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002926 247.0
WLSH2_k127_8456436_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000006222 237.0
WLSH2_k127_8456436_5 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000001201 195.0
WLSH2_k127_8456436_6 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000286 158.0
WLSH2_k127_8456436_7 dksA traR - - - 0.000000000000000000000000000000004603 132.0
WLSH2_k127_8456436_8 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000005147 95.0
WLSH2_k127_8456436_9 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000004038 91.0
WLSH2_k127_8462592_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.745e-206 649.0
WLSH2_k127_8462592_1 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 326.0
WLSH2_k127_8462592_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000004222 222.0
WLSH2_k127_8500878_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 500.0
WLSH2_k127_8500878_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 289.0
WLSH2_k127_8500878_2 PFAM Plasmid stabilisation system protein K06218 - - 0.000000000000000000000000007485 111.0
WLSH2_k127_8500878_3 - - - - 0.0000000000005755 71.0
WLSH2_k127_8500878_4 - - - - 0.000000004149 59.0
WLSH2_k127_8547345_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 518.0
WLSH2_k127_8547345_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
WLSH2_k127_8547345_2 - - - - 0.00000000000001721 80.0
WLSH2_k127_856689_0 SAM-dependent K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 539.0
WLSH2_k127_856689_1 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.0000000000000000000000000000002113 124.0
WLSH2_k127_8580155_0 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 421.0
WLSH2_k127_8580155_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 344.0
WLSH2_k127_8580155_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 286.0
WLSH2_k127_8580155_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000002556 154.0
WLSH2_k127_8580155_4 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000001798 126.0
WLSH2_k127_8580155_5 Cytochrome c - - - 0.000000000000000000003297 96.0
WLSH2_k127_8580155_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000267 77.0
WLSH2_k127_8589727_0 Ion channel K10716 - - 6.444e-212 674.0
WLSH2_k127_8589727_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 301.0
WLSH2_k127_8589727_2 - - - - 0.0000000000000000000000000000000000000000000000000000009072 194.0
WLSH2_k127_8589727_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000004177 153.0
WLSH2_k127_8589727_4 Belongs to the thioredoxin family K05838 - - 0.00000000000000000000000000000000000002559 145.0
WLSH2_k127_8589727_5 Hint domain - - - 0.0000000000000000000001271 104.0
WLSH2_k127_8589727_6 Hydrogenase formation hypA family K04654 GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - 0.0000000000000002403 78.0
WLSH2_k127_8596596_0 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000436 289.0
WLSH2_k127_8596596_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000007948 192.0
WLSH2_k127_8596596_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 0.0000000000001765 71.0
WLSH2_k127_8601061_0 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000008105 248.0
WLSH2_k127_8601061_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000149 72.0
WLSH2_k127_8606473_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.128e-296 917.0
WLSH2_k127_8606473_1 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000000000000000002477 165.0
WLSH2_k127_8606473_2 domain, Protein - - - 0.000000000000000000000000000126 134.0
WLSH2_k127_8632291_0 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001655 276.0
WLSH2_k127_8632291_1 Bacterial SH3 domain - - - 0.000000000000000000000001331 107.0
WLSH2_k127_8637922_0 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 389.0
WLSH2_k127_8637922_1 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000389 186.0
WLSH2_k127_8637922_2 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000003679 144.0
WLSH2_k127_8675155_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009353 557.0
WLSH2_k127_8675155_1 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000000000000000000001655 153.0
WLSH2_k127_8675155_2 - - - - 0.00000000000000000000000000000007464 132.0
WLSH2_k127_8675155_3 - - - - 0.0000000000000000000000000000001719 126.0
WLSH2_k127_8675155_4 RNA recognition motif K03655,K05592 - 3.6.4.12,3.6.4.13 0.00000000000000000000011 106.0
WLSH2_k127_8689811_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 302.0
WLSH2_k127_8689811_1 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000001413 237.0
WLSH2_k127_8689811_2 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000002351 190.0
WLSH2_k127_8689811_3 Amidohydrolase family - - - 0.0000000000000000000001725 98.0
WLSH2_k127_8689811_4 Domain of unknown function (DUF1732) - GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009022,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000183 100.0
WLSH2_k127_8754392_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.963e-252 793.0
WLSH2_k127_8754392_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 606.0
WLSH2_k127_8754392_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 602.0
WLSH2_k127_8754392_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 580.0
WLSH2_k127_8754392_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 300.0
WLSH2_k127_8754392_5 PFAM peptidylprolyl isomerase FKBP-type K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000005212 241.0
WLSH2_k127_8754392_6 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000003657 223.0
WLSH2_k127_8754392_7 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000003096 157.0
WLSH2_k127_8754392_8 Protein of unknown function (DUF2798) - - - 0.00000000000000008707 82.0
WLSH2_k127_8754392_9 beta-lactamase activity K07126,K19292 - - 0.0000000000004037 76.0
WLSH2_k127_8764268_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 468.0
WLSH2_k127_8764268_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 454.0
WLSH2_k127_8764268_2 PFAM peptidase S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 351.0
WLSH2_k127_8764268_3 Nucleotide-binding protein implicated in inhibition of septum formation K06287 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0047429 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001439 265.0
WLSH2_k127_8764268_4 subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000001871 160.0
WLSH2_k127_8764268_5 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000001829 123.0
WLSH2_k127_8764268_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000006518 98.0
WLSH2_k127_877800_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1050.0
WLSH2_k127_877800_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 533.0
WLSH2_k127_877800_2 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 421.0
WLSH2_k127_877800_3 Protein of unknown function (DUF3240) - - - 0.000000000000000000000004926 104.0
WLSH2_k127_8792744_0 Exonuclease C-terminal K01141 - 3.1.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 545.0
WLSH2_k127_8792744_1 Inner membrane component domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003062 243.0
WLSH2_k127_8792744_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000001652 56.0
WLSH2_k127_8792744_3 - - - - 0.0000001937 58.0
WLSH2_k127_8801567_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 428.0
WLSH2_k127_8801567_1 Protein of unknown function (DUF3419) K13622 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 409.0
WLSH2_k127_8801567_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 341.0
WLSH2_k127_8801567_3 transferase activity, transferring acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 294.0
WLSH2_k127_8801567_4 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002946 289.0
WLSH2_k127_8801567_5 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 268.0
WLSH2_k127_8801567_6 dolichyl monophosphate biosynthetic process K00981,K18678 - 2.7.1.182,2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000003094 254.0
WLSH2_k127_8801567_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000002534 222.0
WLSH2_k127_8801567_8 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000008789 107.0
WLSH2_k127_880223_0 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007771 262.0
WLSH2_k127_880223_1 ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000233 190.0
WLSH2_k127_880223_2 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.000000000000000000000001612 115.0
WLSH2_k127_880223_3 membrane transporter protein K07090 - - 0.000000000000000006146 85.0
WLSH2_k127_880223_4 Protein of unknown function (DUF3617) - - - 0.0000006117 58.0
WLSH2_k127_8815685_0 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 1.402e-227 709.0
WLSH2_k127_8815685_1 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000002587 231.0
WLSH2_k127_8815685_2 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000001597 216.0
WLSH2_k127_8815685_3 Preprotein translocase subunit SecG K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000004293 160.0
WLSH2_k127_8815685_4 - - - - 0.000000003151 61.0
WLSH2_k127_882522_0 Histidine kinase K07678 GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 404.0
WLSH2_k127_882522_1 beta (1-6) glucans synthase K01210 - 3.2.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 379.0
WLSH2_k127_882522_2 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 377.0
WLSH2_k127_882522_3 hydrolase (HAD superfamily) K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 321.0
WLSH2_k127_882522_4 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 341.0
WLSH2_k127_882522_5 TIGRFAM 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 311.0
WLSH2_k127_882522_6 PFAM NUDIX hydrolase K08312 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003692 254.0
WLSH2_k127_882522_7 metal cluster binding K06940 - - 0.00000000000000000000000000000000000000000000000000000002691 201.0
WLSH2_k127_882522_8 transport system, periplasmic component - - - 0.00000000000000001385 94.0
WLSH2_k127_882522_9 - - - - 0.000000000009821 70.0
WLSH2_k127_8833161_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 7.385e-220 691.0
WLSH2_k127_8833161_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 362.0
WLSH2_k127_8833161_2 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000003462 173.0
WLSH2_k127_8833161_3 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000002502 164.0
WLSH2_k127_8833161_4 S4 RNA-binding domain K04762 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000001697 141.0
WLSH2_k127_8833161_5 - - - - 0.0000000000000000003673 100.0
WLSH2_k127_8870017_0 PFAM Peptidoglycan-binding lysin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 329.0
WLSH2_k127_8870017_1 PFAM DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 323.0
WLSH2_k127_8870017_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000004442 255.0
WLSH2_k127_8870017_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000001306 224.0
WLSH2_k127_8870017_4 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000000008767 202.0
WLSH2_k127_8870017_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000007604 170.0
WLSH2_k127_8900833_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 573.0
WLSH2_k127_8900833_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 410.0
WLSH2_k127_8900833_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002813 275.0
WLSH2_k127_8918493_0 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 312.0
WLSH2_k127_8918493_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000001446 198.0
WLSH2_k127_8918493_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000005137 138.0
WLSH2_k127_8918493_3 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000008712 103.0
WLSH2_k127_8918493_4 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000005562 72.0
WLSH2_k127_8918725_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 542.0
WLSH2_k127_8918725_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000006676 226.0
WLSH2_k127_8918725_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000001698 181.0
WLSH2_k127_8918725_3 tRNA pseudouridine synthase C K01790 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 0.00000000000000000000000007001 111.0
WLSH2_k127_8939312_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 1.407e-292 906.0
WLSH2_k127_8939312_1 Nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 3.933e-279 862.0
WLSH2_k127_8939312_10 PFAM 4Fe-4S ferredoxin, iron-sulphur binding, subgroup - - - 0.000000000000000000001032 96.0
WLSH2_k127_8939312_11 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.00000000000000000000172 94.0
WLSH2_k127_8939312_12 Metal-binding - - - 0.000000000000000005932 89.0
WLSH2_k127_8939312_13 - - - - 0.0000000000000001575 83.0
WLSH2_k127_8939312_14 - - - - 0.000000002482 67.0
WLSH2_k127_8939312_2 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 529.0
WLSH2_k127_8939312_3 SIR2-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 349.0
WLSH2_k127_8939312_4 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) K05951 - 2.4.2.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 316.0
WLSH2_k127_8939312_5 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000000000000000000000004169 238.0
WLSH2_k127_8939312_6 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000003819 231.0
WLSH2_k127_8939312_7 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000005315 212.0
WLSH2_k127_8939312_8 NifT/FixU protein K02593 - - 0.00000000000000000000003071 100.0
WLSH2_k127_8939312_9 Is required to sustain N(2)-dependent growth in the presence of low levels of carbon monoxide (CO). Probably acts by protecting the N(2) fixation ability of the nitrogenase complex, which is inactivated in the presence of CO K21694 - - 0.00000000000000000000006367 102.0
WLSH2_k127_8971034_0 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 3.834e-242 754.0
WLSH2_k127_8971034_1 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
WLSH2_k127_8971034_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.00000000000000000000000000000000000000006392 152.0
WLSH2_k127_8971062_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000003219 228.0
WLSH2_k127_8971062_1 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000002806 138.0
WLSH2_k127_8971062_2 - - - - 0.000000000000000000000000000001029 125.0
WLSH2_k127_8971062_3 GIY-YIG catalytic domain - - - 0.000000000000000000000002096 108.0
WLSH2_k127_9036427_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 3.148e-200 637.0
WLSH2_k127_9036427_1 - - - - 0.0000000000000005546 86.0
WLSH2_k127_906695_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 494.0
WLSH2_k127_906695_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 302.0
WLSH2_k127_91748_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 451.0
WLSH2_k127_91748_1 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 326.0
WLSH2_k127_91748_2 MazG-like family - - - 0.000000000000000000000000000000000000000000005626 166.0
WLSH2_k127_9183839_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.297e-213 671.0
WLSH2_k127_9183839_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 580.0
WLSH2_k127_9183839_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 502.0
WLSH2_k127_9183839_3 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 252.0
WLSH2_k127_919262_0 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 385.0
WLSH2_k127_919262_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 296.0
WLSH2_k127_9197366_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 389.0
WLSH2_k127_9219079_0 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 428.0
WLSH2_k127_9219079_1 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000001162 204.0
WLSH2_k127_92341_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000138 205.0
WLSH2_k127_92341_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000464 194.0
WLSH2_k127_92341_2 - - - - 0.000000000000000000000000000000000000000000004935 164.0
WLSH2_k127_9246373_0 Aminotransferase class I and II K00817 GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 464.0
WLSH2_k127_9246373_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000006468 215.0
WLSH2_k127_9246373_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000001408 198.0
WLSH2_k127_9254316_0 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000009778 212.0
WLSH2_k127_9254316_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000004296 189.0
WLSH2_k127_9254316_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000004069 118.0
WLSH2_k127_9254316_3 Occluded RNA-recognition motif K13201,K19041 GO:0000003,GO:0000323,GO:0000375,GO:0000377,GO:0000381,GO:0000398,GO:0001817,GO:0001818,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005685,GO:0005737,GO:0005764,GO:0005773,GO:0005829,GO:0006139,GO:0006355,GO:0006357,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006970,GO:0006972,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007276,GO:0007281,GO:0007568,GO:0008104,GO:0008143,GO:0008150,GO:0008152,GO:0008219,GO:0008284,GO:0008340,GO:0008380,GO:0008543,GO:0009266,GO:0009408,GO:0009628,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010033,GO:0010259,GO:0010467,GO:0010468,GO:0010494,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0012501,GO:0016070,GO:0016071,GO:0017091,GO:0017145,GO:0017148,GO:0019219,GO:0019222,GO:0019953,GO:0022412,GO:0022414,GO:0023052,GO:0030154,GO:0030532,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031974,GO:0031981,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0033036,GO:0033365,GO:0034248,GO:0034249,GO:0034613,GO:0034641,GO:0035770,GO:0036464,GO:0042035,GO:0042036,GO:0042127,GO:0042221,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043484,GO:0044237,GO:0044238,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046483,GO:0048024,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048609,GO:0048856,GO:0048869,GO:0050684,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051239,GO:0051241,GO:0051246,GO:0051248,GO:0051252,GO:0051301,GO:0051641,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0070013,GO:0070717,GO:0070727,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0080090,GO:0090304,GO:0097159,GO:0097165,GO:0097525,GO:0120114,GO:1901360,GO:1901363,GO:1903311,GO:1903506,GO:1903608,GO:1904035,GO:1904037,GO:1990904,GO:2000112,GO:2000113,GO:2001141 2.3.2.27 0.00003552 53.0
WLSH2_k127_9254316_4 Bacterial transferase hexapeptide repeat protein - - - 0.0001812 44.0
WLSH2_k127_9260017_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 473.0
WLSH2_k127_9260017_1 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000000000000000007939 132.0
WLSH2_k127_9260017_2 transcriptional regulator K07726 - - 0.0000000000000000005715 91.0
WLSH2_k127_9260017_3 oligosaccharyl transferase activity - - - 0.00000000000000003862 89.0
WLSH2_k127_9260017_4 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.00000000007154 69.0
WLSH2_k127_9293286_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
WLSH2_k127_9293286_1 PFAM Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000001743 229.0
WLSH2_k127_9293286_2 Bacterial protein of unknown function (DUF945) - - - 0.0000000000001041 84.0
WLSH2_k127_9310511_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.41e-228 723.0
WLSH2_k127_9310511_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 464.0
WLSH2_k127_9310511_2 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.00000000000000000000000000000000000000000000000009673 182.0
WLSH2_k127_9310511_3 COG2951 Membrane-bound lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000006735 164.0
WLSH2_k127_9310511_4 Involved in formation and maintenance of cell shape K03570 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007163,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0043621,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944,GO:0071963 - 0.00000000000000000002585 92.0
WLSH2_k127_9325575_0 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 2.516e-223 703.0
WLSH2_k127_9369078_0 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 340.0
WLSH2_k127_9369078_1 membrane organization K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002491 252.0
WLSH2_k127_9369078_2 - - - - 0.00000000000000000000000000000000000007494 151.0
WLSH2_k127_9372921_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 452.0
WLSH2_k127_9372921_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 360.0
WLSH2_k127_9398148_0 Endonuclease K01173 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009383 240.0
WLSH2_k127_9398148_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001119 198.0
WLSH2_k127_9453481_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 286.0
WLSH2_k127_9453481_1 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004641 260.0
WLSH2_k127_9453481_2 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000007567 220.0
WLSH2_k127_9453481_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000002501 175.0
WLSH2_k127_9453481_4 Trehalose utilisation - - - 0.00000003681 56.0
WLSH2_k127_9483313_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 533.0
WLSH2_k127_9483313_1 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 506.0
WLSH2_k127_9483313_2 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 483.0
WLSH2_k127_9483313_3 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 314.0
WLSH2_k127_9484632_0 Peptidase, M16 K06972 - - 4.075e-210 662.0
WLSH2_k127_9502280_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004336 262.0
WLSH2_k127_9502280_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000007721 201.0
WLSH2_k127_9502280_2 COG1226 Kef-type K transport systems - - - 0.00000000000000000868 86.0
WLSH2_k127_9502280_3 - - - - 0.0000000001343 71.0
WLSH2_k127_951460_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 449.0
WLSH2_k127_951460_1 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 315.0
WLSH2_k127_951460_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0
WLSH2_k127_9548705_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1512.0
WLSH2_k127_9548705_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 307.0
WLSH2_k127_9552659_0 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008798 611.0
WLSH2_k127_9552659_1 Nucleoside recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 574.0
WLSH2_k127_9552659_2 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 389.0
WLSH2_k127_9552659_3 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
WLSH2_k127_9552659_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000002346 211.0
WLSH2_k127_9552659_5 DsrC like protein K11179 - - 0.000000000000000000000002551 106.0
WLSH2_k127_9562431_0 Putative transposase - - - 1.19e-210 658.0
WLSH2_k127_9562431_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000005722 104.0
WLSH2_k127_9562431_2 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000009065 104.0
WLSH2_k127_9572306_0 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 350.0
WLSH2_k127_9572306_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000005628 238.0
WLSH2_k127_9572306_2 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000004722 218.0
WLSH2_k127_9572306_3 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000008533 174.0
WLSH2_k127_9572306_4 Mechanosensitive ion channel K05802 - - 0.00000003939 65.0
WLSH2_k127_9588328_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 3.529e-209 656.0
WLSH2_k127_9588328_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000308 228.0
WLSH2_k127_9588328_2 - - - - 0.000000000000000000000000000000000000000734 151.0
WLSH2_k127_9604286_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 3.087e-230 721.0
WLSH2_k127_9606820_0 e3 binding domain K00382 - 1.8.1.4 1.186e-321 1000.0
WLSH2_k127_9606820_1 COG0457 FOG TPR repeat - - - 0.0002033 49.0
WLSH2_k127_9613880_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0050896 - 1.244e-284 880.0
WLSH2_k127_9613880_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 361.0
WLSH2_k127_9613880_2 COG1226 Kef-type K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001137 286.0
WLSH2_k127_9614051_0 Beta-Casp domain K07576 - - 4.57e-211 666.0
WLSH2_k127_9614051_1 - - - - 0.0000000000000000000000000000000000000000005819 165.0
WLSH2_k127_9614051_2 Dodecin K09165 - - 0.000000000000000000000000007682 112.0
WLSH2_k127_9614051_3 carboxymethylenebutenolidase activity K01061,K21105 - 3.1.1.102,3.1.1.45 0.00000000000000002155 84.0
WLSH2_k127_9626634_0 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 319.0
WLSH2_k127_9626634_1 Ankyrin repeats (many copies) - - - 0.000000000000009034 86.0
WLSH2_k127_9645963_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 604.0
WLSH2_k127_9645963_1 spore germination - - - 0.0000000000000000000000000000000000000000000009812 173.0
WLSH2_k127_9647725_0 PFAM Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 504.0
WLSH2_k127_9647725_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000002048 211.0
WLSH2_k127_9647725_2 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 0.000000000000000004009 84.0
WLSH2_k127_9679551_0 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 548.0
WLSH2_k127_9679551_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 466.0
WLSH2_k127_9679551_2 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002294 260.0
WLSH2_k127_9679551_3 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000001778 219.0
WLSH2_k127_9699765_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 576.0
WLSH2_k127_9699765_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 541.0
WLSH2_k127_9699765_2 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000001994 190.0
WLSH2_k127_9699765_3 Chloride channel - - - 0.000000000000000000000000000000000000000000003664 170.0
WLSH2_k127_9699765_4 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000007286 163.0
WLSH2_k127_9699765_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 0.000000000000000000000000000008252 120.0
WLSH2_k127_9699765_6 - - - - 0.0000000000000000000000000001083 124.0
WLSH2_k127_9700608_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 415.0
WLSH2_k127_9700608_1 protein conserved in bacteria K09930 - - 0.00000000004782 63.0
WLSH2_k127_9700608_2 - - - - 0.0001146 49.0
WLSH2_k127_9741033_0 COG2931, RTX toxins and related Ca2 -binding proteins K01127 - 3.1.4.50 2.17e-322 1071.0
WLSH2_k127_9741033_1 TIGRFAM TIGR03032 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 465.0
WLSH2_k127_9741033_2 TIGRFAM TIGR03032 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 416.0
WLSH2_k127_9741033_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000001831 239.0
WLSH2_k127_9741033_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001458 183.0
WLSH2_k127_9741033_5 calcium- and calmodulin-responsive adenylate cyclase activity K20276 - - 0.0000000000000008691 94.0
WLSH2_k127_9741033_6 - - - - 0.0007303 48.0
WLSH2_k127_9748422_0 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 572.0
WLSH2_k127_9748422_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000645 223.0
WLSH2_k127_9764515_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 580.0
WLSH2_k127_9764515_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000004288 198.0
WLSH2_k127_9843315_0 Single-stranded-DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 1.628e-223 704.0
WLSH2_k127_9843315_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 550.0
WLSH2_k127_9843315_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 291.0
WLSH2_k127_9843315_3 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000001593 136.0
WLSH2_k127_9904982_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 511.0
WLSH2_k127_9904982_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 340.0
WLSH2_k127_9904982_2 PFAM NifZ K02597 - - 0.00000000000000000000000000000000000000000000000000002746 194.0
WLSH2_k127_9904982_3 May protect the nitrogenase Fe-Mo protein from oxidative damage K02595 - - 0.0000000000000000000000001133 111.0
WLSH2_k127_9926033_0 Peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000002866 177.0
WLSH2_k127_9926033_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000003529 165.0
WLSH2_k127_9926033_2 COG NOG27188 non supervised orthologous group - - - 0.000000003942 66.0
WLSH2_k127_9934087_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 594.0
WLSH2_k127_9934087_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000008007 108.0