logo

Overview

ID MAG04228
Name WLSH2_bin.62
Sample SMP0110
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanosarcinia
Order Methanotrichales
Family Methanotrichaceae
Genus Methanothrix
Species
Assembly information
Completeness (%) 65.91
Contamination (%) 0.05
GC content (%) 54.0
N50 (bp) 6,281
Genome size (bp) 1,720,754

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1653

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH2_k127_10086721_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14392 - - 7.825e-215 676.0
WLSH2_k127_10086721_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 562.0
WLSH2_k127_10086721_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 508.0
WLSH2_k127_10086721_3 phosphoserine phosphatase activity K01079,K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007081 517.0
WLSH2_k127_10086721_4 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000005387 140.0
WLSH2_k127_10086721_5 Non-histone chromosomal protein MC1 - - - 0.00000000000000000000000000356 113.0
WLSH2_k127_10086721_6 PFAM FecR protein K20276 - - 0.000002203 60.0
WLSH2_k127_10110326_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 490.0
WLSH2_k127_10110326_1 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 312.0
WLSH2_k127_10110326_2 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000002366 239.0
WLSH2_k127_10110326_3 Histidine kinase - - - 0.000000000000000000000001654 105.0
WLSH2_k127_10111356_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000001725 204.0
WLSH2_k127_10111356_1 Putative DNA-binding domain K03655 - 3.6.4.12 0.00002978 52.0
WLSH2_k127_10111356_2 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00003987 55.0
WLSH2_k127_10181847_0 Tetratricopeptide repeat - - - 0.0 1174.0
WLSH2_k127_10181847_1 Mu-like prophage protein gp29 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
WLSH2_k127_10181847_2 Terminase RNaseH-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001987 226.0
WLSH2_k127_10181847_3 - - - - 0.000000000000000000000000000000000002746 142.0
WLSH2_k127_10181847_4 Terminase RNaseH-like domain - - - 0.00000000000001648 81.0
WLSH2_k127_10190044_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 570.0
WLSH2_k127_10190044_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 508.0
WLSH2_k127_10190044_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 356.0
WLSH2_k127_10190044_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000007829 181.0
WLSH2_k127_10190044_4 - - - - 0.000000000000000001343 87.0
WLSH2_k127_10197444_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 482.0
WLSH2_k127_10197444_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 477.0
WLSH2_k127_10197444_2 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 398.0
WLSH2_k127_10197444_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000001261 205.0
WLSH2_k127_10197444_4 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000001264 155.0
WLSH2_k127_10197444_5 Domain of unknown function (DUF4276) - - - 0.000000000000000000000000000000000001005 147.0
WLSH2_k127_10197444_6 - - - - 0.0000000000000000000000000003506 120.0
WLSH2_k127_10204059_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 580.0
WLSH2_k127_10204059_1 CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 419.0
WLSH2_k127_10204059_2 - K03655 - 3.6.4.12 0.00000000000000000000000000000000000003591 143.0
WLSH2_k127_10204059_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000001324 143.0
WLSH2_k127_10204059_4 Psort location Cytoplasmic, score K02503 - - 0.00000000000000007296 86.0
WLSH2_k127_10204059_5 EamA-like transporter family - - - 0.000000000438 71.0
WLSH2_k127_10208762_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 408.0
WLSH2_k127_10208762_1 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000519 257.0
WLSH2_k127_10208762_2 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000001644 141.0
WLSH2_k127_10208762_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000014 135.0
WLSH2_k127_10338623_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 298.0
WLSH2_k127_10338623_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000001284 184.0
WLSH2_k127_10338623_2 - - - - 0.0000000271 60.0
WLSH2_k127_10338623_3 - - - - 0.0003014 47.0
WLSH2_k127_10525989_0 Cna B domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 339.0
WLSH2_k127_10525989_1 Nucleotidyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000007405 194.0
WLSH2_k127_10525989_2 HEPN domain - - - 0.0000000000000000000000000000000000003966 144.0
WLSH2_k127_10525989_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000003584 98.0
WLSH2_k127_10525989_4 repeat-containing protein - - - 0.0000000005009 69.0
WLSH2_k127_10525989_5 Transcriptional regulator - - - 0.00000007956 58.0
WLSH2_k127_10525989_6 - - - - 0.0001011 44.0
WLSH2_k127_10579836_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 309.0
WLSH2_k127_10579836_1 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000001828 209.0
WLSH2_k127_10579836_2 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000003607 112.0
WLSH2_k127_10579836_3 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000003601 61.0
WLSH2_k127_10609316_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000006067 113.0
WLSH2_k127_10609316_1 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000002334 112.0
WLSH2_k127_10609316_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000001122 89.0
WLSH2_k127_1062207_0 S-layer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 507.0
WLSH2_k127_1062207_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 353.0
WLSH2_k127_1062207_2 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 295.0
WLSH2_k127_10663836_0 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 449.0
WLSH2_k127_10663836_1 PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001862 267.0
WLSH2_k127_10663836_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000000007749 195.0
WLSH2_k127_10663836_3 Transcriptional regulator K07108 - - 0.0000000000000000000000000002367 117.0
WLSH2_k127_10663836_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000001108 57.0
WLSH2_k127_10720593_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 433.0
WLSH2_k127_10720593_1 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 309.0
WLSH2_k127_10720593_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000003305 266.0
WLSH2_k127_10720593_3 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000000000000000000000000005393 176.0
WLSH2_k127_10720593_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000002697 149.0
WLSH2_k127_10720593_5 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.00000000000000000000000000000005476 136.0
WLSH2_k127_10720593_6 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000007397 134.0
WLSH2_k127_10720593_7 Histidine kinase - - - 0.00000000000000005705 94.0
WLSH2_k127_10720593_8 GlcNAc-PI de-N-acetylase - - - 0.0000000000009335 80.0
WLSH2_k127_10720593_9 beta-lactamase domain protein - - - 0.0000000001979 62.0
WLSH2_k127_10906501_0 Subtilase family K14743 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 299.0
WLSH2_k127_10906501_1 NB-ARC domain - - - 0.0000000000000000000000000000000000000000000000000000000005084 227.0
WLSH2_k127_10906501_2 NACHT nucleoside triphosphatase K12132 - 2.7.11.1 0.00000000000000000000000000000000007967 154.0
WLSH2_k127_10944470_0 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000001055 230.0
WLSH2_k127_10944470_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000005709 188.0
WLSH2_k127_10944470_2 PFAM Nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000000000000005205 123.0
WLSH2_k127_10944470_3 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000006382 83.0
WLSH2_k127_10947236_0 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000214 248.0
WLSH2_k127_10947236_1 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000008621 216.0
WLSH2_k127_10947236_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001597 171.0
WLSH2_k127_10947236_3 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000001517 122.0
WLSH2_k127_10947236_4 negative regulation of transcription, DNA-templated K03655,K10947 - 3.6.4.12 0.0000000000000000000000000008244 121.0
WLSH2_k127_10947236_5 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000000000005694 101.0
WLSH2_k127_10947236_6 Putative DNA-binding domain - - - 0.000000000001953 73.0
WLSH2_k127_10950424_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 599.0
WLSH2_k127_10950424_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 342.0
WLSH2_k127_10950424_2 Domain of unknown function (DUF4277) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
WLSH2_k127_10950424_3 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000008978 184.0
WLSH2_k127_10950424_4 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000004577 98.0
WLSH2_k127_10950424_5 Acylphosphatase K01512 - 3.6.1.7 0.0000008322 52.0
WLSH2_k127_10951378_0 PFAM 4Fe-4S - - - 0.0000000000000000000000000000000000000001172 157.0
WLSH2_k127_10951378_1 Permease - - - 0.00000000000000000000000000000000000003479 156.0
WLSH2_k127_10951378_2 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000707 141.0
WLSH2_k127_11003520_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001325 278.0
WLSH2_k127_11003520_1 Divergent AAA domain protein K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002341 285.0
WLSH2_k127_11003520_2 - - - - 0.0000000000000000000000001295 117.0
WLSH2_k127_11003520_3 - - - - 0.000000000000000000000001449 106.0
WLSH2_k127_11003520_4 - - - - 0.000000000000000000006517 101.0
WLSH2_k127_11003520_5 positive regulation of proteasomal protein catabolic process - GO:0001763,GO:0002009,GO:0003401,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006950,GO:0007275,GO:0008150,GO:0009653,GO:0009791,GO:0009887,GO:0009888,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010468,GO:0010604,GO:0012505,GO:0019222,GO:0030154,GO:0030162,GO:0030323,GO:0030324,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0033554,GO:0034976,GO:0035239,GO:0035295,GO:0040007,GO:0042176,GO:0042692,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045732,GO:0045862,GO:0048286,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048729,GO:0048731,GO:0048747,GO:0048754,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051146,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051716,GO:0055001,GO:0055002,GO:0060255,GO:0060425,GO:0060429,GO:0060441,GO:0060447,GO:0060541,GO:0060560,GO:0060562,GO:0060602,GO:0061061,GO:0061136,GO:0061138,GO:0065007,GO:0080090,GO:1901800,GO:1903050,GO:1903052,GO:1903362,GO:1903364 - 0.00001072 49.0
WLSH2_k127_11009102_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.71e-226 714.0
WLSH2_k127_11009102_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 515.0
WLSH2_k127_11009102_10 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000004596 171.0
WLSH2_k127_11009102_11 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.000000000000000000000000000000000000002927 156.0
WLSH2_k127_11009102_12 Protein of unknown function (DUF447) K09154 - - 0.0000000000000000000000000000003912 129.0
WLSH2_k127_11009102_13 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000007825 105.0
WLSH2_k127_11009102_14 Putative small multi-drug export protein - - - 0.00000000000000000009444 90.0
WLSH2_k127_11009102_15 Belongs to the acylphosphatase family - - - 0.000000000000000006385 90.0
WLSH2_k127_11009102_16 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000282 84.0
WLSH2_k127_11009102_17 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000001204 82.0
WLSH2_k127_11009102_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 358.0
WLSH2_k127_11009102_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 298.0
WLSH2_k127_11009102_4 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 301.0
WLSH2_k127_11009102_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000271 269.0
WLSH2_k127_11009102_6 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002047 244.0
WLSH2_k127_11009102_7 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004543 242.0
WLSH2_k127_11009102_8 Dihydrouridine synthase (Dus) - - - 0.00000000000000000000000000000000000000000000000000000000000001121 227.0
WLSH2_k127_11009102_9 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000001768 222.0
WLSH2_k127_11057022_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.429e-200 649.0
WLSH2_k127_11057022_1 Nacht domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 308.0
WLSH2_k127_11057022_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000001986 228.0
WLSH2_k127_1110510_0 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000002439 169.0
WLSH2_k127_1110510_1 PIN domain - - - 0.0000000001269 64.0
WLSH2_k127_11105528_0 Pfam:DUF955 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 497.0
WLSH2_k127_11105528_1 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 467.0
WLSH2_k127_11105528_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008465 403.0
WLSH2_k127_11105528_3 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 370.0
WLSH2_k127_11105528_4 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 364.0
WLSH2_k127_11105528_5 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000001632 233.0
WLSH2_k127_11105528_6 Domain of unknown function (DUF4411) - - - 0.00000000000000000000000000000000000000000000000000000002975 200.0
WLSH2_k127_11105528_7 PFAM Plasmid pRiA4b ORF-3-like protein - - - 0.00005571 47.0
WLSH2_k127_11105528_8 Plasmid pRiA4b ORF-3-like protein - - - 0.0004317 43.0
WLSH2_k127_11113674_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 516.0
WLSH2_k127_11113674_1 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 323.0
WLSH2_k127_11113674_2 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005673 226.0
WLSH2_k127_11113674_3 Related to alanyl-tRNA synthetase HxxxH domain K01872,K07050 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000002075 219.0
WLSH2_k127_11113674_4 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000004357 121.0
WLSH2_k127_11113674_5 protein conserved in archaea - - - 0.0000000000000000000000000003061 117.0
WLSH2_k127_11113674_6 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000581 117.0
WLSH2_k127_11113674_7 COG1793 ATP-dependent DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000006101 59.0
WLSH2_k127_11348710_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 5.739e-284 884.0
WLSH2_k127_11348710_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.749e-274 861.0
WLSH2_k127_11348710_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 461.0
WLSH2_k127_11348710_3 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.00000000000000000000000000000000000000000000000000000008324 199.0
WLSH2_k127_11363633_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 347.0
WLSH2_k127_11363633_1 4Fe-4S dicluster domain K00196 - - 0.000000000000000000000000000000000000000000000000004973 185.0
WLSH2_k127_11363633_2 PFAM GvpD gas vesicle - - - 0.00000000000000000000000009258 117.0
WLSH2_k127_11363633_3 Belongs to the acylphosphatase family - - - 0.000000000000000002994 91.0
WLSH2_k127_11414666_0 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.000000000000000007567 95.0
WLSH2_k127_11467990_0 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 469.0
WLSH2_k127_11467990_1 membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 444.0
WLSH2_k127_11467990_2 Flavoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
WLSH2_k127_11467990_3 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.00000000000000000000000000000000000000000000000000000000000002362 230.0
WLSH2_k127_11467990_4 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.000000000000000000000000000009592 124.0
WLSH2_k127_11467990_5 LemA family K03744 - - 0.0000000000000000000004137 98.0
WLSH2_k127_11467990_6 NADPH-dependent FMN reductase - - - 0.00000000000000007073 80.0
WLSH2_k127_11467990_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000003685 64.0
WLSH2_k127_11477141_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.372e-269 848.0
WLSH2_k127_11477141_1 beta-lactamase - - - 0.00000000000000001063 86.0
WLSH2_k127_11557438_0 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 301.0
WLSH2_k127_1158801_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 312.0
WLSH2_k127_1172324_0 choline dehydrogenase activity - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000008983 253.0
WLSH2_k127_1172324_1 - - - - 0.000000000000007695 81.0
WLSH2_k127_1193878_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 388.0
WLSH2_k127_1193878_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 310.0
WLSH2_k127_1193878_2 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000601 275.0
WLSH2_k127_1193878_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000007483 260.0
WLSH2_k127_1193878_4 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000000003769 235.0
WLSH2_k127_1193878_5 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000006587 166.0
WLSH2_k127_1193878_6 - - - - 0.000000000316 70.0
WLSH2_k127_1202731_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 8.581e-217 682.0
WLSH2_k127_1202731_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000006282 138.0
WLSH2_k127_1202731_2 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000003139 84.0
WLSH2_k127_1212372_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 1.9e-231 728.0
WLSH2_k127_1212372_1 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000007974 186.0
WLSH2_k127_1224717_0 - - - - 0.0000000000000000000000000000000000002886 147.0
WLSH2_k127_1224717_1 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000002452 138.0
WLSH2_k127_1224717_2 extracellular matrix structural constituent - - - 0.0004627 52.0
WLSH2_k127_1239431_0 citrate synthase K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 551.0
WLSH2_k127_1239431_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 528.0
WLSH2_k127_1239431_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 409.0
WLSH2_k127_1239431_3 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 302.0
WLSH2_k127_1239431_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000009484 246.0
WLSH2_k127_1239431_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000003465 201.0
WLSH2_k127_1239431_6 - - - - 0.00000000000007157 77.0
WLSH2_k127_1239431_7 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000003601 61.0
WLSH2_k127_1239431_8 Belongs to the HesB IscA family K13628 - - 0.000008665 53.0
WLSH2_k127_125338_0 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000001047 176.0
WLSH2_k127_125338_1 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000002212 175.0
WLSH2_k127_125338_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000009901 134.0
WLSH2_k127_125338_3 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000004529 52.0
WLSH2_k127_1292864_0 defense response to virus K07061 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 349.0
WLSH2_k127_1292864_1 crispr-associated protein K07016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 343.0
WLSH2_k127_1292864_2 RAMP superfamily K19076,K19142 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 335.0
WLSH2_k127_1292864_3 PFAM DNA polymerase beta domain protein region K07076 - - 0.0000000000000000000000000000000000001594 147.0
WLSH2_k127_1292864_4 PFAM CRISPR-associated protein, GSU0054 K19132 - - 0.00000000000000364 82.0
WLSH2_k127_1317577_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1080.0
WLSH2_k127_1317577_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.272e-236 749.0
WLSH2_k127_1317577_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 550.0
WLSH2_k127_1317577_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 432.0
WLSH2_k127_1317577_4 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 301.0
WLSH2_k127_1317577_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001304 273.0
WLSH2_k127_1317577_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000007671 154.0
WLSH2_k127_1321209_0 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 539.0
WLSH2_k127_1321209_1 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 518.0
WLSH2_k127_1321209_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 299.0
WLSH2_k127_1321209_3 Involved in protein export K03074 - - 0.00000000000000000000000000000000000000000000000000000000000007538 221.0
WLSH2_k127_1321209_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000002038 154.0
WLSH2_k127_1321209_5 protein kinase activity - - - 0.00000000000000000000000000000000663 148.0
WLSH2_k127_1321209_6 - - - - 0.000000000006934 72.0
WLSH2_k127_1321209_7 TPR-like protein K11788,K15201 GO:0000127,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005667,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006383,GO:0006384,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009303,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0018130,GO:0019438,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0042791,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044798,GO:0046483,GO:0071704,GO:0090304,GO:0090576,GO:0097659,GO:0098781,GO:1901360,GO:1901362,GO:1901576 6.3.3.1,6.3.4.13 0.0000847 56.0
WLSH2_k127_1354735_0 Deacetylase, histone deacetylase acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 297.0
WLSH2_k127_1354735_1 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000001949 204.0
WLSH2_k127_1354735_2 Dodecin K09165 - - 0.00000000000000007389 84.0
WLSH2_k127_1354735_3 protein homooligomerization K18555 - - 0.0001269 53.0
WLSH2_k127_1397302_0 Serine dehydrogenase proteinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 366.0
WLSH2_k127_1397302_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
WLSH2_k127_1397302_2 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000001696 135.0
WLSH2_k127_1451340_0 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000002682 155.0
WLSH2_k127_1451340_1 Cold shock protein K03704 - - 0.000000000000003105 77.0
WLSH2_k127_1466067_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 1.977e-297 923.0
WLSH2_k127_1466067_1 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 317.0
WLSH2_k127_1466067_10 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000000000000000007271 156.0
WLSH2_k127_1466067_11 HEPN domain - - - 0.0000000000000000000000000006275 117.0
WLSH2_k127_1466067_12 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000008316 71.0
WLSH2_k127_1466067_13 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.00000008285 55.0
WLSH2_k127_1466067_14 nucleotidyltransferase activity - - - 0.0000003712 55.0
WLSH2_k127_1466067_15 Pas domain - - - 0.0001752 49.0
WLSH2_k127_1466067_16 Nucleotidyltransferase domain K07076 - - 0.0002231 46.0
WLSH2_k127_1466067_2 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000001991 251.0
WLSH2_k127_1466067_3 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000006649 242.0
WLSH2_k127_1466067_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000000003692 190.0
WLSH2_k127_1466067_5 4Fe-4S dicluster domain K00196 - - 0.000000000000000000000000000000000000000000000000006832 186.0
WLSH2_k127_1466067_6 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000000113 197.0
WLSH2_k127_1466067_7 methyltransferase activity K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000001186 184.0
WLSH2_k127_1466067_8 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000009334 176.0
WLSH2_k127_1466067_9 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000000000000000000000000001108 169.0
WLSH2_k127_153725_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001903 237.0
WLSH2_k127_153725_1 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000001176 139.0
WLSH2_k127_153725_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000782 117.0
WLSH2_k127_153725_3 Staphylococcal nuclease homologue - - - 0.0000000188 61.0
WLSH2_k127_153725_4 Metallo-peptidase family M12B Reprolysin-like - - - 0.000001154 59.0
WLSH2_k127_1557639_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 516.0
WLSH2_k127_1557639_1 4Fe-4S dicluster domain - - - 0.00000000000000003835 82.0
WLSH2_k127_1557639_2 Protein of unknown function DUF116 K09729 - - 0.000000000000005421 75.0
WLSH2_k127_1561264_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 426.0
WLSH2_k127_1561264_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001916 243.0
WLSH2_k127_1561264_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000008865 204.0
WLSH2_k127_1561264_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001742 162.0
WLSH2_k127_1568001_0 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000001911 102.0
WLSH2_k127_1568001_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000006988 93.0
WLSH2_k127_1568001_2 Protein of unknown function (DUF2283) - - - 0.00000004085 55.0
WLSH2_k127_1568001_3 mRNA binding - - - 0.0000003612 54.0
WLSH2_k127_1568001_4 Protein of unknown function DUF104 - - - 0.00001507 49.0
WLSH2_k127_1568001_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.0007442 43.0
WLSH2_k127_1629622_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 2.348e-275 859.0
WLSH2_k127_1629622_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 4.133e-239 756.0
WLSH2_k127_1629622_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000002923 169.0
WLSH2_k127_1670332_0 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 394.0
WLSH2_k127_1670332_1 PFAM peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 257.0
WLSH2_k127_1670332_2 serine-type aminopeptidase activity K02030,K14475 - - 0.00000000000000002218 85.0
WLSH2_k127_1670332_3 - - - - 0.000000000000002285 83.0
WLSH2_k127_1686046_0 Protein of unknown function (DUF1646) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 375.0
WLSH2_k127_1686046_1 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 301.0
WLSH2_k127_1686046_2 Protein of unknown function (DUF1646) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 288.0
WLSH2_k127_1686046_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000007236 216.0
WLSH2_k127_1686046_4 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000001387 179.0
WLSH2_k127_1686046_5 Protein of unknown function (DUF1646) - - - 0.0000000000000001137 89.0
WLSH2_k127_1713336_0 Peptidase family C69 - - - 4.489e-280 871.0
WLSH2_k127_1713336_1 Flavin containing amine oxidoreductase - - - 1.139e-218 684.0
WLSH2_k127_1713336_10 extracellular matrix structural constituent - - - 0.0000000000000000000000000002219 126.0
WLSH2_k127_1713336_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001004 115.0
WLSH2_k127_1713336_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 585.0
WLSH2_k127_1713336_3 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 569.0
WLSH2_k127_1713336_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 561.0
WLSH2_k127_1713336_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 310.0
WLSH2_k127_1713336_6 Putative ATP-dependent DNA helicase recG C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004498 266.0
WLSH2_k127_1713336_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001881 255.0
WLSH2_k127_1713336_8 PFAM methyltransferase small K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000982 192.0
WLSH2_k127_1713336_9 Transcriptional regulator K03655 - 3.6.4.12 0.00000000000000000000000000000000001972 138.0
WLSH2_k127_1720434_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 5.718e-230 726.0
WLSH2_k127_1720434_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000006162 204.0
WLSH2_k127_1720434_2 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000005778 187.0
WLSH2_k127_1720434_3 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000003402 169.0
WLSH2_k127_1720434_4 dihydropteroate synthase - - - 0.00000000000000000000000000000001504 129.0
WLSH2_k127_1720434_5 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000009064 121.0
WLSH2_k127_1720434_6 Binds to the 23S rRNA K02896 - - 0.00000000000000000001811 91.0
WLSH2_k127_1720434_7 - - - - 0.000000185 62.0
WLSH2_k127_1736421_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.18e-201 640.0
WLSH2_k127_1736421_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 289.0
WLSH2_k127_1736421_2 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009769 274.0
WLSH2_k127_1736421_3 Copper-exporting ATPase K17686 - 3.6.3.54 0.0000000002149 65.0
WLSH2_k127_1754650_0 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K16370 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 351.0
WLSH2_k127_1754650_1 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K16305 - 2.2.1.11,4.1.2.13 0.0000000000000000000000000000003114 124.0
WLSH2_k127_1754650_2 Transposase K07484 - - 0.000000008282 57.0
WLSH2_k127_1757231_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.329e-207 652.0
WLSH2_k127_1757231_1 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 477.0
WLSH2_k127_1763339_0 TspO/MBR family K05770 - - 0.00000000000000000000000000000000000000000000000001234 184.0
WLSH2_k127_1763339_1 PFAM Cupin - - - 0.0000000000000000000000000000000000000008112 153.0
WLSH2_k127_1779962_0 PFAM Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1495.0
WLSH2_k127_1779962_1 PFAM DNA methylase K07316 - 2.1.1.72 0.0 1158.0
WLSH2_k127_1779962_2 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 438.0
WLSH2_k127_1779962_3 Pfam:DUF955 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 357.0
WLSH2_k127_1779962_4 COG1226 Kef-type K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003081 250.0
WLSH2_k127_1779962_5 nuclease activity K18828 - - 0.0000000000000000000000000000000000000000003739 163.0
WLSH2_k127_1779962_6 - - - - 0.00000000000000000000000000000006986 130.0
WLSH2_k127_1779962_7 - - - - 0.000000000008799 69.0
WLSH2_k127_1791417_0 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 417.0
WLSH2_k127_1791417_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 429.0
WLSH2_k127_1791417_10 B-block binding subunit of TFIIIC - - - 0.0000000000000000000003987 100.0
WLSH2_k127_1791417_11 NifU-like domain - - - 0.0000000000000000002748 89.0
WLSH2_k127_1791417_12 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000002353 81.0
WLSH2_k127_1791417_13 - - - - 0.000000000000003727 79.0
WLSH2_k127_1791417_14 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000004335 72.0
WLSH2_k127_1791417_2 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 366.0
WLSH2_k127_1791417_3 Putative Fe-S cluster K11260 - - 0.0000000000000000000000000000000000000000000000000000000001221 207.0
WLSH2_k127_1791417_4 PFAM Phosphatidylglycerophosphatase A - - - 0.000000000000000000000000000000000000000000000000000000389 197.0
WLSH2_k127_1791417_5 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.000000000000000000000000000000000000000000000000004169 188.0
WLSH2_k127_1791417_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000002849 184.0
WLSH2_k127_1791417_7 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000002038 157.0
WLSH2_k127_1791417_8 PFAM Like-Sm ribonucleoprotein, core - - - 0.00000000000000000000000006914 108.0
WLSH2_k127_1791417_9 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.00000000000000000000002972 102.0
WLSH2_k127_1820985_0 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 393.0
WLSH2_k127_1820985_1 - - - - 0.00000000000000000000000000000000000000000000000000008615 207.0
WLSH2_k127_1820985_2 Ion channel - - - 0.000000001487 70.0
WLSH2_k127_1820985_3 Pentapeptide repeats (9 copies) - - - 0.00002211 56.0
WLSH2_k127_1872645_0 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 570.0
WLSH2_k127_1872645_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 351.0
WLSH2_k127_1872645_2 PFAM regulatory protein, ArsR K03892,K21903 - - 0.000000000000000000216 91.0
WLSH2_k127_1874111_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 473.0
WLSH2_k127_1874111_1 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
WLSH2_k127_1874111_2 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000006676 196.0
WLSH2_k127_1874111_3 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000000000007384 177.0
WLSH2_k127_1874111_4 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000007666 115.0
WLSH2_k127_1896433_0 - - - - 0.00000000000000000000000000000000000000000000803 168.0
WLSH2_k127_1896433_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000001641 136.0
WLSH2_k127_1970931_0 Metallo-beta-lactamase superfamily K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 324.0
WLSH2_k127_1970931_1 Lysine-specific metallo-endopeptidase K08646 - 3.4.24.20 0.0000000000000000000000000000000000000000000000000000000000003041 233.0
WLSH2_k127_1970931_2 mannose-ethanolamine phosphotransferase activity - - - 0.000000000000000000000000000000000000006173 165.0
WLSH2_k127_1970931_3 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000000000000000000000004064 146.0
WLSH2_k127_1970931_4 PFAM Thioredoxin K03671 - - 0.00000000000000000000005389 100.0
WLSH2_k127_1970931_5 - - - - 0.0000000000000000009505 92.0
WLSH2_k127_2012245_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 582.0
WLSH2_k127_2012245_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 531.0
WLSH2_k127_2012245_2 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 511.0
WLSH2_k127_2012245_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000001733 209.0
WLSH2_k127_2012245_4 PFAM Lon protease (S16) C-terminal proteolytic domain K06870 - - 0.00000000000000000000005185 109.0
WLSH2_k127_2012245_5 COG0517 FOG CBS domain - - - 0.00000000000000000002966 94.0
WLSH2_k127_2033374_0 PFAM amino acid-binding ACT domain protein K06862 - - 0.00000000000000000000000000000000006976 134.0
WLSH2_k127_2033374_1 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.000000000000000000003398 94.0
WLSH2_k127_2033374_2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone - - - 0.000000000000001198 78.0
WLSH2_k127_2033374_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.0000000006455 60.0
WLSH2_k127_2044631_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000115 161.0
WLSH2_k127_2044631_1 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000004061 138.0
WLSH2_k127_204547_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 336.0
WLSH2_k127_204547_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000362 269.0
WLSH2_k127_204547_2 DEAD DEAH box helicase domain protein K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000001932 143.0
WLSH2_k127_204547_4 Methyltransferase domain - - - 0.00000000000001989 83.0
WLSH2_k127_2070775_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 481.0
WLSH2_k127_2070775_1 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000003876 182.0
WLSH2_k127_2070775_2 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000004484 191.0
WLSH2_k127_2070775_3 SpoVT / AbrB like domain - - - 0.00001716 49.0
WLSH2_k127_2082137_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.727e-208 657.0
WLSH2_k127_2082137_1 ATP synthase alpha/beta chain, C terminal domain K02111 - 3.6.3.14 1.229e-195 621.0
WLSH2_k127_2082137_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001796 254.0
WLSH2_k127_2082137_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000244 162.0
WLSH2_k127_2082137_4 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000000000000001007 151.0
WLSH2_k127_2082137_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000242 130.0
WLSH2_k127_2082137_6 TIGRFAM F0F1-ATPase subunit K02116 - - 0.00000000000000000000000000001643 120.0
WLSH2_k127_2082137_7 N-ATPase, AtpR subunit - - - 0.0000000000005983 72.0
WLSH2_k127_2082137_8 ATP synthase K02115 - - 0.00000000004918 65.0
WLSH2_k127_2096170_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 552.0
WLSH2_k127_2096170_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 365.0
WLSH2_k127_2096170_2 COG3547 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000003705 248.0
WLSH2_k127_2096170_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000002673 124.0
WLSH2_k127_2096170_4 membrane-bound metal-dependent hydrolase - - - 0.000000000000000000002268 100.0
WLSH2_k127_2096170_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773,K18779 - 2.4.2.29,2.4.2.48 0.000000000000000004907 84.0
WLSH2_k127_2096170_6 DNA polymerase beta palm K07076 - - 0.000000000000001781 79.0
WLSH2_k127_2096170_7 Protein of unknown function (DUF2283) - - - 0.000000003247 61.0
WLSH2_k127_2096170_8 TIGRFAM CRISPR-associated protein, Csx3 family K19144 - - 0.0002478 46.0
WLSH2_k127_2096170_9 Transcriptional regulator - - - 0.0005285 46.0
WLSH2_k127_2113919_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 3.826e-250 782.0
WLSH2_k127_2113919_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.543e-227 734.0
WLSH2_k127_2113919_2 PFAM Fic DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 477.0
WLSH2_k127_2113919_3 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 415.0
WLSH2_k127_2113919_4 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000000000000000000000000000002136 157.0
WLSH2_k127_2113919_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000115 149.0
WLSH2_k127_2113919_6 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000448 71.0
WLSH2_k127_2131665_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1102.0
WLSH2_k127_2131665_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000001269 218.0
WLSH2_k127_2131665_2 InterPro IPR007367 - - - 0.00000000000000000000000006093 110.0
WLSH2_k127_2131665_3 PIN domain of ribonuclease K07060 - - 0.000000000000000000001333 99.0
WLSH2_k127_2131665_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000004617 50.0
WLSH2_k127_2131665_5 - - - - 0.0005817 44.0
WLSH2_k127_2174342_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 428.0
WLSH2_k127_2174342_1 PFAM glutamate--cysteine ligase, GCS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 419.0
WLSH2_k127_2174342_10 Transcriptional regulator - - - 0.00000000003123 66.0
WLSH2_k127_2174342_11 RimK-like ATPgrasp N-terminal domain - - - 0.0000000008987 62.0
WLSH2_k127_2174342_12 Domain of unknown function (DUF4130 K21929 - 3.2.2.27 0.0001565 52.0
WLSH2_k127_2174342_2 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 413.0
WLSH2_k127_2174342_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 402.0
WLSH2_k127_2174342_4 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
WLSH2_k127_2174342_5 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 298.0
WLSH2_k127_2174342_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000006981 199.0
WLSH2_k127_2174342_7 - - - - 0.000000000000000000000000000000000000000000002247 177.0
WLSH2_k127_2174342_8 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000009176 147.0
WLSH2_k127_2174342_9 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000116 118.0
WLSH2_k127_2201078_0 Mu-like prophage protein gp29 - - - 0.000000000000000000000000000000000003912 145.0
WLSH2_k127_2201078_1 Putative phage serine protease XkdF - - - 0.0000000001613 74.0
WLSH2_k127_2201078_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000002147 60.0
WLSH2_k127_2260405_0 PFAM Receptor family ligand binding region K01999,K11954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 308.0
WLSH2_k127_2260405_1 pfam gyd - - - 0.0000000000000000000000000001376 118.0
WLSH2_k127_2260405_2 Integrase core domain - - - 0.0000000000000000005572 90.0
WLSH2_k127_2260405_3 peptidase - - - 0.0000000000000003132 78.0
WLSH2_k127_2260405_4 Pentapeptide repeats (9 copies) - - - 0.00000001007 68.0
WLSH2_k127_2260405_5 COG3387 Glucoamylase and related glycosyl hydrolases K01178 - 3.2.1.3 0.0008175 45.0
WLSH2_k127_2265962_0 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 530.0
WLSH2_k127_2265962_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000003392 211.0
WLSH2_k127_2265962_2 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000001408 133.0
WLSH2_k127_2265962_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000002132 111.0
WLSH2_k127_2265962_4 Predicted membrane protein (DUF2254) - - - 0.000000000000000000001831 109.0
WLSH2_k127_2265962_5 Nuclease (SNase domain-containing protein) - - - 0.000000000000003615 84.0
WLSH2_k127_2265962_6 nuclease - - - 0.0000005011 59.0
WLSH2_k127_2283138_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 604.0
WLSH2_k127_2283138_1 Has ATPase and non-specific DNA-binding activities K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 423.0
WLSH2_k127_2283138_2 - - - - 0.0000000000000000000000000000002629 132.0
WLSH2_k127_2283138_3 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000003139 93.0
WLSH2_k127_2283138_4 PFAM Protein kinase domain - - - 0.000001277 58.0
WLSH2_k127_2284196_0 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000002245 189.0
WLSH2_k127_2284196_1 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000001799 178.0
WLSH2_k127_2284196_2 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000004607 67.0
WLSH2_k127_2284196_3 - - - - 0.000000007796 57.0
WLSH2_k127_2356887_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 537.0
WLSH2_k127_2356887_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 494.0
WLSH2_k127_2356887_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 420.0
WLSH2_k127_2356887_3 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 314.0
WLSH2_k127_2356887_4 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000001596 83.0
WLSH2_k127_2356887_5 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000001521 70.0
WLSH2_k127_2356887_6 TIGRFAM alpha-L-glutamate ligase, RimK family K15740 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0044424,GO:0044464 6.3.2.33 0.000000803 51.0
WLSH2_k127_2365806_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0 1398.0
WLSH2_k127_2365806_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 6.735e-223 700.0
WLSH2_k127_2365806_2 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000002734 140.0
WLSH2_k127_2365806_3 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000000000000009744 128.0
WLSH2_k127_2365806_4 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000000000000000001733 108.0
WLSH2_k127_2365806_5 META domain K03668 - - 0.000000000000000000007002 104.0
WLSH2_k127_2389657_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 539.0
WLSH2_k127_2389657_1 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000004418 235.0
WLSH2_k127_2389657_2 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001165 226.0
WLSH2_k127_2389657_3 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000003104 147.0
WLSH2_k127_2389657_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000082 100.0
WLSH2_k127_2389657_5 Mediates influx of magnesium ions - - - 0.00000003059 62.0
WLSH2_k127_2430487_0 PFAM Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 507.0
WLSH2_k127_2430487_1 Belongs to the AAA ATPase family K07392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 406.0
WLSH2_k127_2430487_2 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000000009917 199.0
WLSH2_k127_2430487_3 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000001559 189.0
WLSH2_k127_2430487_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000005811 79.0
WLSH2_k127_2434804_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 551.0
WLSH2_k127_2434804_1 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 415.0
WLSH2_k127_2434804_2 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000009419 220.0
WLSH2_k127_2434804_3 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000000000000000883 201.0
WLSH2_k127_2434804_4 Permease - - - 0.000000000000000000000000000000000000000000000007566 185.0
WLSH2_k127_2434804_5 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000001365 130.0
WLSH2_k127_2436768_0 Domain of unknown function DUF11 - - - 0.0000000000000001088 95.0
WLSH2_k127_250380_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 391.0
WLSH2_k127_250380_1 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 329.0
WLSH2_k127_250380_2 Putative RNA methyltransferase K09142 - - 0.0000000000000000000000000000000000000000000000000000000000000001699 233.0
WLSH2_k127_250380_3 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000004754 154.0
WLSH2_k127_250380_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000003062 124.0
WLSH2_k127_250380_5 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000001166 102.0
WLSH2_k127_2505156_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001326 285.0
WLSH2_k127_2505156_1 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000001648 144.0
WLSH2_k127_2505156_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000018 122.0
WLSH2_k127_2505156_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000001138 94.0
WLSH2_k127_2568471_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 374.0
WLSH2_k127_2568471_1 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
WLSH2_k127_2568471_2 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000006302 176.0
WLSH2_k127_2568471_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000001391 156.0
WLSH2_k127_2568471_4 Phosphate uptake regulator - - - 0.0000000000000000000000000003049 119.0
WLSH2_k127_2568471_5 Phosphate uptake regulator, PhoU - - - 0.00000000000000000001287 98.0
WLSH2_k127_2573036_0 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000003702 162.0
WLSH2_k127_2573036_3 EamA-like transporter family - - - 0.00000000000003974 83.0
WLSH2_k127_2573036_4 secreted hydrolase - - - 0.0000007732 61.0
WLSH2_k127_2587302_0 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 417.0
WLSH2_k127_2587302_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000006812 214.0
WLSH2_k127_2587302_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000002054 193.0
WLSH2_k127_2587302_3 - - - - 0.00000000000000000000007321 98.0
WLSH2_k127_2587302_4 B-block binding subunit of TFIIIC - - - 0.00001179 52.0
WLSH2_k127_2614384_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 301.0
WLSH2_k127_2614384_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000005305 194.0
WLSH2_k127_2614384_2 PFAM Aldehyde dehydrogenase K22187 - - 0.0009522 42.0
WLSH2_k127_2625079_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000003633 212.0
WLSH2_k127_2625079_1 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000000000001723 162.0
WLSH2_k127_2625079_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000533 66.0
WLSH2_k127_2660412_0 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 319.0
WLSH2_k127_2660412_1 Belongs to the UPF0248 family K09715 - - 0.000000000000000000001118 97.0
WLSH2_k127_2672592_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000005689 259.0
WLSH2_k127_2672592_1 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000002123 216.0
WLSH2_k127_2672592_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000001076 155.0
WLSH2_k127_2683188_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 7.872e-197 629.0
WLSH2_k127_2683188_1 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000006045 76.0
WLSH2_k127_2683188_2 TIGRFAM integral membrane protein, TerC family K05794 - - 0.0003276 44.0
WLSH2_k127_269502_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 9.316e-253 782.0
WLSH2_k127_269502_1 alkylhydroperoxidase like protein, AhpD family - - - 0.000000000000000000000000000189 117.0
WLSH2_k127_269502_2 Belongs to the acylphosphatase family - - - 0.00000000000000000003912 96.0
WLSH2_k127_2702777_0 Tex-like protein N-terminal domain K06959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 521.0
WLSH2_k127_2702777_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 496.0
WLSH2_k127_2702777_2 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000009395 75.0
WLSH2_k127_2711350_0 PFAM ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 296.0
WLSH2_k127_2711350_1 PFAM SufBD protein K07033 - - 0.00000000000000000006474 93.0
WLSH2_k127_2711350_2 Tetratricopeptide repeat - - - 0.000000006102 62.0
WLSH2_k127_2715965_0 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 385.0
WLSH2_k127_2715965_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 386.0
WLSH2_k127_2715965_2 Tetratricopeptide repeat - - - 0.0000283 51.0
WLSH2_k127_2744526_0 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 410.0
WLSH2_k127_2744526_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 361.0
WLSH2_k127_2744526_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000448 68.0
WLSH2_k127_2744526_11 Belongs to the peptidase S8 family - - - 0.00006773 51.0
WLSH2_k127_2744526_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 344.0
WLSH2_k127_2744526_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
WLSH2_k127_2744526_4 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008194 279.0
WLSH2_k127_2744526_5 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002253 245.0
WLSH2_k127_2744526_6 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000122 231.0
WLSH2_k127_2744526_7 Benzoate transporter - - - 0.000000000000000000000003512 112.0
WLSH2_k127_2744526_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000003746 66.0
WLSH2_k127_2744526_9 Lrp/AsnC ligand binding domain - - - 0.0000000003885 65.0
WLSH2_k127_2768425_0 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 424.0
WLSH2_k127_2768425_1 - - - - 0.000000000000000000000000000000000000000002538 166.0
WLSH2_k127_2793225_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1112.0
WLSH2_k127_2793225_1 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000006801 60.0
WLSH2_k127_2822184_0 SMART Elongator protein 3 MiaB NifB - - - 2.859e-235 738.0
WLSH2_k127_2822184_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 586.0
WLSH2_k127_2822184_10 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000009532 86.0
WLSH2_k127_2822184_11 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000001892 83.0
WLSH2_k127_2822184_2 Clp protease K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 408.0
WLSH2_k127_2822184_3 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 334.0
WLSH2_k127_2822184_4 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000001741 244.0
WLSH2_k127_2822184_5 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000000000000000000181 166.0
WLSH2_k127_2822184_6 domain, Protein - - - 0.000000000000000000000000000000000003591 160.0
WLSH2_k127_2822184_7 Large family of predicted nucleotide-binding domains K07158 - - 0.00000000000000000000000004387 114.0
WLSH2_k127_2822184_8 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000000000000604 105.0
WLSH2_k127_2822184_9 Belongs to the acylphosphatase family - - - 0.00000000000000000003811 98.0
WLSH2_k127_2864576_0 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000001662 162.0
WLSH2_k127_2864576_1 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.0000000000000000000000000000000000154 140.0
WLSH2_k127_2864576_2 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000007049 106.0
WLSH2_k127_2864576_3 - - - - 0.0000000003503 66.0
WLSH2_k127_2899668_0 Integral membrane sensor signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 486.0
WLSH2_k127_2909641_0 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 327.0
WLSH2_k127_2909641_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 321.0
WLSH2_k127_2909641_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.00000000000000000000000000000000000007309 145.0
WLSH2_k127_2909641_3 Sodium:solute symporter family K03307 - - 0.0000000000000006694 80.0
WLSH2_k127_2909641_4 Sodium:solute symporter family K03307 - - 0.00001448 49.0
WLSH2_k127_2933493_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 399.0
WLSH2_k127_2933493_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 321.0
WLSH2_k127_2933493_2 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000001503 230.0
WLSH2_k127_2933493_3 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000001182 181.0
WLSH2_k127_2933493_4 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000001509 107.0
WLSH2_k127_2975698_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 1.767e-220 700.0
WLSH2_k127_2975698_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 0.000000000000000000000000000000000000000000000005698 175.0
WLSH2_k127_2975698_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.00000000000000000000000000000000002534 141.0
WLSH2_k127_3004127_0 PFAM Fic DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 500.0
WLSH2_k127_3004127_1 NACHT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003126 299.0
WLSH2_k127_3004127_2 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005138 231.0
WLSH2_k127_3004127_3 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000009188 115.0
WLSH2_k127_3004127_4 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00005495 48.0
WLSH2_k127_3100201_0 Phage plasmid primase, P4 K06919 - - 0.00000000000000000000000000000000000000000000000000000000000000000002096 248.0
WLSH2_k127_3100201_1 TPR Domain containing protein - - - 0.000000000000000000000000000000000000000000001066 186.0
WLSH2_k127_3144956_0 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 518.0
WLSH2_k127_3144956_1 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 376.0
WLSH2_k127_3144956_10 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.000005372 60.0
WLSH2_k127_3144956_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002868 283.0
WLSH2_k127_3144956_3 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003372 273.0
WLSH2_k127_3144956_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004869 273.0
WLSH2_k127_3144956_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001032 267.0
WLSH2_k127_3144956_6 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000001795 217.0
WLSH2_k127_3144956_7 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000001184 201.0
WLSH2_k127_3144956_8 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000000002872 87.0
WLSH2_k127_3144956_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000003279 93.0
WLSH2_k127_3156510_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 449.0
WLSH2_k127_3156510_1 PFAM cobalamin synthesis protein P47K - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 387.0
WLSH2_k127_3156510_10 - K21495 - - 0.00000001082 59.0
WLSH2_k127_3156510_11 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00004291 52.0
WLSH2_k127_3156510_12 TIGRFAM addiction module toxin, RelE StbE family K19158 - - 0.0001491 49.0
WLSH2_k127_3156510_2 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 359.0
WLSH2_k127_3156510_3 PFAM Fe-S cluster domain protein K06939 - - 0.00000000000000000000000000000000000000000000000000000000000002304 219.0
WLSH2_k127_3156510_4 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000008522 211.0
WLSH2_k127_3156510_5 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000001891 196.0
WLSH2_k127_3156510_6 PFAM Fe-S cluster domain protein K06939 - - 0.0000000000000000000000000000000000000000000000007166 178.0
WLSH2_k127_3156510_7 Transcriptional regulator K09714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000344 101.0
WLSH2_k127_3156510_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000000001723 96.0
WLSH2_k127_3156510_9 PQ loop repeat - - - 0.00000000000000308 79.0
WLSH2_k127_3364550_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 454.0
WLSH2_k127_3364550_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000003532 196.0
WLSH2_k127_3364550_2 PFAM TM2 domain containing protein - - - 0.00001516 49.0
WLSH2_k127_3372548_0 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 328.0
WLSH2_k127_3372548_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 331.0
WLSH2_k127_3372548_10 Predicted RNA-binding protein K06964 - - 0.000000002744 61.0
WLSH2_k127_3372548_11 Probably involved in the biogenesis of the ribosome K14561 - - 0.0002234 50.0
WLSH2_k127_3372548_2 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 322.0
WLSH2_k127_3372548_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006648 277.0
WLSH2_k127_3372548_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000000005092 139.0
WLSH2_k127_3372548_5 binds to the 23S rRNA K02921 - - 0.00000000000000000000000000001132 120.0
WLSH2_k127_3372548_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000005387 97.0
WLSH2_k127_3372548_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000001233 88.0
WLSH2_k127_3372548_8 Transcription factor Pcc1 K09741 - - 0.000000000000134 72.0
WLSH2_k127_3372548_9 - - - - 0.00000000006247 66.0
WLSH2_k127_3379678_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 398.0
WLSH2_k127_3379678_1 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 336.0
WLSH2_k127_3379678_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 325.0
WLSH2_k127_3379678_3 ABC 3 transport family K02015 - - 0.0000000000000000000000000000000000000000000000000000000000003517 216.0
WLSH2_k127_3385688_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 584.0
WLSH2_k127_3385688_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000134 71.0
WLSH2_k127_3403591_0 S-layer protein - - - 0.00000000000000000000000000000000000000000009763 171.0
WLSH2_k127_3403591_1 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000002212 148.0
WLSH2_k127_3403591_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000009918 85.0
WLSH2_k127_3403591_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000004811 54.0
WLSH2_k127_345627_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 309.0
WLSH2_k127_345627_1 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001575 243.0
WLSH2_k127_345627_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000273 168.0
WLSH2_k127_3477863_0 TIR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006643 226.0
WLSH2_k127_3477863_1 ftsk spoiiie - - - 0.000000000000000000000000000001039 128.0
WLSH2_k127_3477863_2 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000005272 121.0
WLSH2_k127_3477863_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000008982 116.0
WLSH2_k127_3477863_4 TIR domain - - - 0.0000000000000000000001015 100.0
WLSH2_k127_3477863_5 Possibly the antitoxin component of a - - - 0.000000000000000009299 84.0
WLSH2_k127_3477863_6 sequence-specific DNA binding - - - 0.000000000000001411 82.0
WLSH2_k127_3477863_7 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000007315 63.0
WLSH2_k127_3477863_8 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000166 49.0
WLSH2_k127_3482893_0 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 445.0
WLSH2_k127_3482893_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 428.0
WLSH2_k127_3482893_2 ATPases associated with a variety of cellular activities K02074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 378.0
WLSH2_k127_3482893_3 formylmethanofuran dehydrogenase, subunit E - - - 0.0000000000000000000000000000000000000000000000000000000000003644 214.0
WLSH2_k127_3482893_4 ATPases associated with a variety of cellular activities K02032 - - 0.00000000000000000000000000000000000000000000000000000000002734 214.0
WLSH2_k127_3482893_5 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000003715 193.0
WLSH2_k127_3482893_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000007066 126.0
WLSH2_k127_3482893_7 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000007701 96.0
WLSH2_k127_3494849_0 Proprotein convertase P-domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 584.0
WLSH2_k127_3494849_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 441.0
WLSH2_k127_3494849_2 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 410.0
WLSH2_k127_3494849_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000004567 224.0
WLSH2_k127_3498465_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000005241 164.0
WLSH2_k127_3498465_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000006149 115.0
WLSH2_k127_3498465_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000003296 73.0
WLSH2_k127_3508925_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.489e-227 716.0
WLSH2_k127_3565686_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 1.232e-221 704.0
WLSH2_k127_3565686_1 PFAM Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000001144 192.0
WLSH2_k127_3565686_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000006966 80.0
WLSH2_k127_3565686_3 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000001285 77.0
WLSH2_k127_3565686_4 - - - - 0.0000000001528 64.0
WLSH2_k127_3565686_5 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.00007035 49.0
WLSH2_k127_3606824_0 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 578.0
WLSH2_k127_3606824_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 361.0
WLSH2_k127_3606824_2 PFAM CobN magnesium chelatase K02230 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000002568 256.0
WLSH2_k127_3606824_3 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 244.0
WLSH2_k127_3606824_4 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000006457 166.0
WLSH2_k127_3606824_5 Uncharacterized protein conserved in archaea (DUF2209) - - - 0.0000000000000000000000000001187 119.0
WLSH2_k127_3667558_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 3.576e-273 860.0
WLSH2_k127_3667558_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 560.0
WLSH2_k127_3667558_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 446.0
WLSH2_k127_3667558_3 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 330.0
WLSH2_k127_3667558_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 332.0
WLSH2_k127_3667558_5 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005839 259.0
WLSH2_k127_3667558_6 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000003605 98.0
WLSH2_k127_3667558_7 peptidyl-tyrosine sulfation - - - 0.0005313 51.0
WLSH2_k127_3694467_0 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000002851 229.0
WLSH2_k127_3694467_1 - - - - 0.0000000000000000000000000000000000000000004132 171.0
WLSH2_k127_3694467_2 Thioredoxin K03671 - - 0.000000000000000000000000000000000000004209 150.0
WLSH2_k127_3694467_3 Protein of unknown function (DUF1638) - - - 0.0002845 44.0
WLSH2_k127_3724815_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005997 250.0
WLSH2_k127_3724815_1 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000001403 254.0
WLSH2_k127_3724815_2 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000002832 120.0
WLSH2_k127_3724815_3 Transcriptional regulator - - - 0.00000007717 57.0
WLSH2_k127_3829427_0 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000003579 105.0
WLSH2_k127_3829427_1 cyclopropane-fatty-acyl-phospholipid synthase K00574,K15256,K15257 - 2.1.1.79 0.00000000000000000003129 92.0
WLSH2_k127_3829427_2 Belongs to the 'phage' integrase family - - - 0.0002432 50.0
WLSH2_k127_3854730_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 1.505e-218 695.0
WLSH2_k127_3854730_1 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 348.0
WLSH2_k127_3854730_2 PFAM amino acid-binding ACT domain protein K06862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 310.0
WLSH2_k127_3854730_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 303.0
WLSH2_k127_3854730_4 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 289.0
WLSH2_k127_3854730_5 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000006175 214.0
WLSH2_k127_3854730_6 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000000000000009912 147.0
WLSH2_k127_3854730_7 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.0000000000000000003791 90.0
WLSH2_k127_3854730_8 Histone-like transcription factor (CBF/NF-Y) and archaeal histone - - - 0.000000000000002155 78.0
WLSH2_k127_3861048_0 Protein of unknown function (DUF460) K09150 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 508.0
WLSH2_k127_3861048_1 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004539 278.0
WLSH2_k127_38626_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.544e-202 638.0
WLSH2_k127_38626_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 555.0
WLSH2_k127_38626_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 516.0
WLSH2_k127_38626_3 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000003853 188.0
WLSH2_k127_38626_4 Belongs to the UPF0434 family - - - 0.000000000000000000000002731 104.0
WLSH2_k127_3963127_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 325.0
WLSH2_k127_3963127_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000008029 207.0
WLSH2_k127_3963127_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000003925 183.0
WLSH2_k127_3963127_3 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000000000000000000000000003621 156.0
WLSH2_k127_3963127_4 membrane - - - 0.0000000000000000000000000000000002555 141.0
WLSH2_k127_3978097_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.163e-224 706.0
WLSH2_k127_3978097_1 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 353.0
WLSH2_k127_3978097_2 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000001665 219.0
WLSH2_k127_3978097_3 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000025 171.0
WLSH2_k127_3978097_4 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000005827 146.0
WLSH2_k127_3978097_5 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.0000002088 55.0
WLSH2_k127_3978097_6 4Fe-4S dicluster domain - - - 0.0000003248 52.0
WLSH2_k127_4047708_0 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001326 285.0
WLSH2_k127_4047708_1 TIGRFAM toxin secretion phage lysis holin - - - 0.00000000000000000000000000000002975 131.0
WLSH2_k127_4047708_2 - - - - 0.000000000000000000000000239 111.0
WLSH2_k127_4047708_3 Belongs to the peptidase S8 family K13274,K13276,K14645 - - 0.00001641 56.0
WLSH2_k127_4047708_4 - - - - 0.00002766 52.0
WLSH2_k127_4054905_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.202e-207 668.0
WLSH2_k127_4054905_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000003302 140.0
WLSH2_k127_4054905_2 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.00000000000000000000000005412 108.0
WLSH2_k127_4054905_3 Belongs to the UPF0200 family - - - 0.000000000000000006146 85.0
WLSH2_k127_40712_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.83e-237 747.0
WLSH2_k127_40712_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 456.0
WLSH2_k127_40712_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 324.0
WLSH2_k127_40712_3 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
WLSH2_k127_4117607_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 328.0
WLSH2_k127_4117607_1 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005918 226.0
WLSH2_k127_4117607_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000001837 171.0
WLSH2_k127_4117607_3 Subtilase family - - - 0.0000000000000000000000000000000000000000000003192 185.0
WLSH2_k127_4117607_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000106 186.0
WLSH2_k127_4117607_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000003275 161.0
WLSH2_k127_4117607_6 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.00000000000000000000000000000000000001204 147.0
WLSH2_k127_4117607_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000000077 98.0
WLSH2_k127_4150106_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.634e-311 970.0
WLSH2_k127_4150106_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 448.0
WLSH2_k127_4150106_2 Belongs to the group II decarboxylase family. MfnA subfamily K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 409.0
WLSH2_k127_4150106_3 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 333.0
WLSH2_k127_4150106_4 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000001091 183.0
WLSH2_k127_4150106_5 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000001643 120.0
WLSH2_k127_4150106_6 TRAM domain - - - 0.000000000000000002814 85.0
WLSH2_k127_4178955_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1024.0
WLSH2_k127_4178955_1 DNA methylase K07316 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 480.0
WLSH2_k127_4187143_0 LOR SDH bifunctional enzyme conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 497.0
WLSH2_k127_4187143_1 RNA ligase K07468 - 6.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008628 347.0
WLSH2_k127_4187143_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005709 280.0
WLSH2_k127_4187143_3 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000191 261.0
WLSH2_k127_4187143_4 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
WLSH2_k127_424036_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 557.0
WLSH2_k127_424036_1 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 357.0
WLSH2_k127_424036_2 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000164 190.0
WLSH2_k127_424036_3 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.0000000000000000000000000001605 119.0
WLSH2_k127_4242068_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.134e-202 636.0
WLSH2_k127_4242068_1 Involved in cell shape control K22222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
WLSH2_k127_4242068_2 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 361.0
WLSH2_k127_4242068_3 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 329.0
WLSH2_k127_4242068_4 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000003706 241.0
WLSH2_k127_4242068_5 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000001466 179.0
WLSH2_k127_4242068_6 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000004083 156.0
WLSH2_k127_4242068_7 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000005619 157.0
WLSH2_k127_4242068_8 - - - - 0.00000000007023 74.0
WLSH2_k127_4242068_9 - - - - 0.0000002148 59.0
WLSH2_k127_4298480_0 PLD-like domain - - - 1.306e-210 670.0
WLSH2_k127_4298480_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 348.0
WLSH2_k127_4298480_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006798 271.0
WLSH2_k127_4298480_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000003776 104.0
WLSH2_k127_4332659_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 484.0
WLSH2_k127_4332659_1 Domain of unknown function (DUF362) K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 455.0
WLSH2_k127_4332659_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 475.0
WLSH2_k127_4332659_3 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001012 281.0
WLSH2_k127_4332659_4 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001304 237.0
WLSH2_k127_4332659_5 Belongs to the GbsR family K22109 - - 0.00000001691 63.0
WLSH2_k127_4357699_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 6.891e-288 900.0
WLSH2_k127_4357699_1 ATPases associated with a variety of cellular activities K00400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 612.0
WLSH2_k127_4357699_2 Uncharacterized protein conserved in archaea (DUF2114) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 589.0
WLSH2_k127_4357699_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 512.0
WLSH2_k127_4357699_4 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 327.0
WLSH2_k127_4415882_0 PFAM ribonuclease II K01147 - 3.1.13.1 2.073e-198 630.0
WLSH2_k127_4415882_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 337.0
WLSH2_k127_4415882_2 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 300.0
WLSH2_k127_4415882_3 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000001914 209.0
WLSH2_k127_4415882_4 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000006575 203.0
WLSH2_k127_4415882_6 Winged helix-turn-helix - - - 0.00000001733 61.0
WLSH2_k127_4415882_7 HNH endonuclease - - - 0.0000006007 57.0
WLSH2_k127_4431427_0 Lycopene cyclase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000034 297.0
WLSH2_k127_4431427_1 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000002269 235.0
WLSH2_k127_4431427_2 Eco57I restriction-modification methylase - - - 0.000000000000008105 75.0
WLSH2_k127_4431427_3 - - - - 0.000000000003659 72.0
WLSH2_k127_4431427_4 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000005126 66.0
WLSH2_k127_4431427_5 HEPN domain - - - 0.0003961 46.0
WLSH2_k127_4453946_0 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 421.0
WLSH2_k127_4453946_1 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003598 250.0
WLSH2_k127_453477_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1304.0
WLSH2_k127_453477_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 481.0
WLSH2_k127_453477_2 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 482.0
WLSH2_k127_453477_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 403.0
WLSH2_k127_453477_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000006061 233.0
WLSH2_k127_453477_5 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.000000000000000000000000000000000000000000000000000000000000002285 219.0
WLSH2_k127_453477_6 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000000187 191.0
WLSH2_k127_453477_7 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000002251 168.0
WLSH2_k127_453477_8 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000000000001893 114.0
WLSH2_k127_4572525_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 3.823e-241 757.0
WLSH2_k127_4572525_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 399.0
WLSH2_k127_4572525_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 395.0
WLSH2_k127_4572525_3 COG3436 Transposase and inactivated derivatives K07484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 295.0
WLSH2_k127_4572525_4 - K00960 - 2.7.7.6 0.00000000000000718 76.0
WLSH2_k127_4651624_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 7.827e-280 869.0
WLSH2_k127_4651624_1 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 4.701e-274 866.0
WLSH2_k127_4682250_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1548.0
WLSH2_k127_4682250_1 PFAM PEBP family protein K06910 - - 0.00000000000000773 77.0
WLSH2_k127_4682250_2 S-layer like family, C-terminal region - - - 0.00006268 55.0
WLSH2_k127_4748527_0 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 299.0
WLSH2_k127_4748527_1 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004248 259.0
WLSH2_k127_4748527_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000005718 236.0
WLSH2_k127_4748527_3 SPTR Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000006966 106.0
WLSH2_k127_4748527_4 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000002809 87.0
WLSH2_k127_4748527_5 sequence-specific DNA binding - - - 0.000000000000001168 91.0
WLSH2_k127_4801466_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K22167 - 1.5.98.3 1.212e-197 636.0
WLSH2_k127_4801466_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K22161 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 451.0
WLSH2_k127_4801466_10 - - - - 0.0000000000001338 74.0
WLSH2_k127_4801466_11 PFAM HD domain - - - 0.000000008694 59.0
WLSH2_k127_4801466_12 - - - - 0.000008741 49.0
WLSH2_k127_4801466_13 Predicted nucleotidyltransferase K07074 - - 0.00007121 54.0
WLSH2_k127_4801466_14 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K22165 - 1.5.98.3 0.0001212 48.0
WLSH2_k127_4801466_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 338.0
WLSH2_k127_4801466_3 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 334.0
WLSH2_k127_4801466_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000003067 248.0
WLSH2_k127_4801466_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K22159 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000175 242.0
WLSH2_k127_4801466_6 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K22166 - 1.5.98.3 0.0000000000000000000000000000000003848 135.0
WLSH2_k127_4801466_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000435 120.0
WLSH2_k127_4801466_8 4Fe-4S dicluster domain K22164 - 1.5.98.3 0.00000000000000000000003275 106.0
WLSH2_k127_4801466_9 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000001849 81.0
WLSH2_k127_4839770_0 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 542.0
WLSH2_k127_4839770_1 OmpA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 503.0
WLSH2_k127_4839770_2 - - - - 0.000000000000000000000000000000000000000000000000000000126 198.0
WLSH2_k127_4839770_3 DNA circulation - - - 0.00000000000000000000000000000000000000000000000000007419 191.0
WLSH2_k127_4839770_4 - - - - 0.000000000000000000000000000000000000000000000000889 180.0
WLSH2_k127_4839770_5 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000126 147.0
WLSH2_k127_4839770_6 - - - - 0.0000000000000000000000000000000001227 137.0
WLSH2_k127_4839770_7 Phospholipase D. Active site motifs. - - - 0.000000000000000000000000000000002777 151.0
WLSH2_k127_4839770_8 - - - - 0.0000000000000000000000000000005687 133.0
WLSH2_k127_4839770_9 B12 binding domain - - - 0.0000000000000000008779 90.0
WLSH2_k127_49200_0 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 584.0
WLSH2_k127_49200_1 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 497.0
WLSH2_k127_49200_2 Radical SAM K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 293.0
WLSH2_k127_49200_3 Bacterial transferase hexapeptide (six repeats) K02617 - - 0.000000000000000000000000000000000000000000001385 171.0
WLSH2_k127_49200_4 DNA-binding transcription factor activity - - - 0.00000000000000000000000001815 114.0
WLSH2_k127_49200_5 Transposase and inactivated derivatives - - - 0.000000000000000004172 93.0
WLSH2_k127_500458_0 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 345.0
WLSH2_k127_500458_1 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 326.0
WLSH2_k127_500458_2 MscS Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003478 263.0
WLSH2_k127_500458_3 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000001341 114.0
WLSH2_k127_500458_4 - - - - 0.000000000000001503 83.0
WLSH2_k127_500458_5 Nuclease (SNase domain-containing protein) - - - 0.000000009123 65.0
WLSH2_k127_5020767_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000173 278.0
WLSH2_k127_5020767_1 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002033 253.0
WLSH2_k127_5020767_2 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002452 248.0
WLSH2_k127_5020767_3 Necessary for normal cell division and for the maintenance of normal septation - - - 0.00000000000000000000000000000000000000000000000000000000000002364 222.0
WLSH2_k127_5020767_4 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.0000000000000000000000000000000000000000000000002602 189.0
WLSH2_k127_5020767_5 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000001388 132.0
WLSH2_k127_5020767_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000003736 123.0
WLSH2_k127_5020767_7 - - - - 0.000000000000000000000001817 109.0
WLSH2_k127_5020767_8 Uncharacterised protein family (UPF0153) K06940 - - 0.0000003106 59.0
WLSH2_k127_502192_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 419.0
WLSH2_k127_502192_1 Uncharacterized conserved protein (DUF2299) - - - 0.0000000000000000000000000000000004129 137.0
WLSH2_k127_502192_2 protein N-acetylglucosaminyltransferase activity K12600 - - 0.00000000000000005004 91.0
WLSH2_k127_502192_3 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000004741 59.0
WLSH2_k127_502192_4 Domain of unknown function DUF11 - - - 0.0000002052 64.0
WLSH2_k127_502192_5 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000006241 59.0
WLSH2_k127_502192_6 Zn-ribbon protein possibly nucleic acid-binding - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001127 59.0
WLSH2_k127_502192_7 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000002408 53.0
WLSH2_k127_5042672_0 CRISPR-associated protein, Crm2 family K07016,K19076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 304.0
WLSH2_k127_5042672_1 defense response to virus K07061 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 299.0
WLSH2_k127_5042672_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000000000000000000002391 205.0
WLSH2_k127_5042672_3 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000000000000000000000004201 178.0
WLSH2_k127_5042672_4 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000195 155.0
WLSH2_k127_5042672_5 PFAM CRISPR-associated protein, GSU0054 K19132 - - 0.000000000000000000000000000000000000009841 154.0
WLSH2_k127_5042672_6 nucleotidyltransferase activity - - - 0.0000000000000000401 86.0
WLSH2_k127_5042672_7 HEPN domain - - - 0.000000000000003407 78.0
WLSH2_k127_5042672_8 Acylphosphatase K01512 - 3.6.1.7 0.0000000001248 69.0
WLSH2_k127_5198620_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 485.0
WLSH2_k127_5198620_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 402.0
WLSH2_k127_5198620_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 359.0
WLSH2_k127_5198620_3 Domain of unknown function (DUF1743) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
WLSH2_k127_5198620_4 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000000000004373 201.0
WLSH2_k127_5198620_5 hydrolase K04794 - 3.1.1.29 0.00000000000000000000000000000000004248 137.0
WLSH2_k127_522894_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 304.0
WLSH2_k127_522894_1 - - - - 0.000000000000000000000000007697 114.0
WLSH2_k127_522894_2 Family of unknown function (DUF5350) - - - 0.00000000003951 64.0
WLSH2_k127_522894_3 - - - - 0.000007097 54.0
WLSH2_k127_5261972_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.022e-198 628.0
WLSH2_k127_5261972_1 Domain of unknown function (DUF1947) K07575 - - 0.0000000000000000000000000000000000000001469 156.0
WLSH2_k127_5261972_2 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000000000001947 113.0
WLSH2_k127_5261972_3 Stage II sporulation protein M - - - 0.00000000000000000000000004125 119.0
WLSH2_k127_5261972_4 binds to the 23S rRNA K02922 - - 0.00000000000001558 74.0
WLSH2_k127_5304271_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.47e-322 1003.0
WLSH2_k127_5304271_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 308.0
WLSH2_k127_5304271_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000001387 120.0
WLSH2_k127_5304271_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000002593 117.0
WLSH2_k127_5373818_0 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 460.0
WLSH2_k127_5373818_1 LOR SDH bifunctional protein conserved domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 331.0
WLSH2_k127_5373818_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 304.0
WLSH2_k127_5373818_3 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005327 277.0
WLSH2_k127_5373818_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000002058 115.0
WLSH2_k127_5373818_5 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000000000000003471 82.0
WLSH2_k127_5375492_0 Belongs to the WrbA family K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000008039 259.0
WLSH2_k127_5375492_1 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000004032 232.0
WLSH2_k127_5375492_2 tRNAHis guanylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005647 203.0
WLSH2_k127_5375492_3 PFAM PRC-barrel domain - - - 0.0000000000000000001845 90.0
WLSH2_k127_5375492_4 - - - - 0.0000000000001778 81.0
WLSH2_k127_5375492_5 DNA integration - - - 0.00000817 51.0
WLSH2_k127_5413964_0 PFAM Cation K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 364.0
WLSH2_k127_5413964_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001876 195.0
WLSH2_k127_5413964_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000004979 158.0
WLSH2_k127_5413964_3 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000113 116.0
WLSH2_k127_5423704_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 8.301e-196 620.0
WLSH2_k127_5423704_1 ABC-type Fe3 -siderophore transport system, permease component K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 426.0
WLSH2_k127_5423704_2 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000652 174.0
WLSH2_k127_5423704_3 Winged helix-turn-helix - - - 0.00000731 51.0
WLSH2_k127_5438600_0 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 542.0
WLSH2_k127_5438600_1 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 473.0
WLSH2_k127_5438600_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000003857 62.0
WLSH2_k127_5448256_0 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000007448 212.0
WLSH2_k127_5448256_1 Domain of unknown function (DUF4357) - - - 0.0000000000000000000000000000000000000000003382 162.0
WLSH2_k127_5448256_2 mRNA binding - - - 0.00000000000000001493 84.0
WLSH2_k127_5448256_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000001204 82.0
WLSH2_k127_5448256_4 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000008134 69.0
WLSH2_k127_547210_0 Glycogen debranching enzyme - - - 0.0 1333.0
WLSH2_k127_547210_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.114e-196 619.0
WLSH2_k127_547210_2 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001854 242.0
WLSH2_k127_5472865_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 2505.0
WLSH2_k127_5472865_1 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003915 286.0
WLSH2_k127_5483386_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 381.0
WLSH2_k127_5483386_1 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 302.0
WLSH2_k127_5483386_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000008513 188.0
WLSH2_k127_5483386_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000132 148.0
WLSH2_k127_5483386_4 S-layer protein - - - 0.00000000000000000000000000001114 124.0
WLSH2_k127_5502187_0 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 454.0
WLSH2_k127_5502187_1 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 435.0
WLSH2_k127_5502187_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 385.0
WLSH2_k127_5502187_3 PDGLE domain K02007,K02009 - - 0.00000000000000000000000000000000000000000001337 163.0
WLSH2_k127_5508472_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002311 254.0
WLSH2_k127_5508472_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000001089 160.0
WLSH2_k127_5508472_3 Lamin Tail Domain - - - 0.000000000000000000000000003305 115.0
WLSH2_k127_5508472_4 Phosphomethylpyrimidine kinase - - - 0.000000000000411 72.0
WLSH2_k127_5508472_5 Protein tyrosine kinase - - - 0.0000005113 61.0
WLSH2_k127_5508472_6 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000007245 51.0
WLSH2_k127_5536347_0 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 607.0
WLSH2_k127_5536347_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 588.0
WLSH2_k127_5536347_2 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 532.0
WLSH2_k127_5536347_3 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 491.0
WLSH2_k127_5536347_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000001599 236.0
WLSH2_k127_5536347_5 Formylmethanofuran dehydrogenase subunit D K00203 - 1.2.7.12 0.000000000000000000000000000005046 123.0
WLSH2_k127_5536347_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000009109 93.0
WLSH2_k127_5566596_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 291.0
WLSH2_k127_5566596_1 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000017 273.0
WLSH2_k127_5566596_2 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000000000000000006874 220.0
WLSH2_k127_5566596_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000001179 155.0
WLSH2_k127_5573776_0 - - - - 0.0000000000608 67.0
WLSH2_k127_5584566_0 PFAM ABC transporter K00400 - - 3.658e-215 682.0
WLSH2_k127_5584566_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 537.0
WLSH2_k127_5584566_10 - - - - 0.00000000001182 73.0
WLSH2_k127_5584566_11 KilA-N - - - 0.00000001484 57.0
WLSH2_k127_5584566_12 positive regulation of translation, ncRNA-mediated K03666 - - 0.00006664 48.0
WLSH2_k127_5584566_2 Putative ATP-dependent DNA helicase recG C-terminal K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 402.0
WLSH2_k127_5584566_3 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 347.0
WLSH2_k127_5584566_4 PFAM Glutamine cyclotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003327 268.0
WLSH2_k127_5584566_5 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000004652 226.0
WLSH2_k127_5584566_6 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000001815 185.0
WLSH2_k127_5584566_7 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000000000000000000000001785 174.0
WLSH2_k127_5584566_8 Universal stress protein family - - - 0.000000000000000000000002285 108.0
WLSH2_k127_5584566_9 Dodecin K09165 - - 0.000000000000000000007387 94.0
WLSH2_k127_5627375_0 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 439.0
WLSH2_k127_5627375_1 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000004509 77.0
WLSH2_k127_5627375_2 AAA domain - - - 0.000000000004872 75.0
WLSH2_k127_5634023_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 454.0
WLSH2_k127_5634023_1 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 302.0
WLSH2_k127_5634023_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000001917 181.0
WLSH2_k127_5634023_3 - - - - 0.000000000000000000000000000136 117.0
WLSH2_k127_5634023_4 chorismate mutase K04093 - 5.4.99.5 0.00000000000000000009855 91.0
WLSH2_k127_5634023_5 Universal stress protein family - - - 0.0000000000000000001614 93.0
WLSH2_k127_5634023_6 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000001759 87.0
WLSH2_k127_5634023_7 Uncharacterised protein family (UPF0175) - - - 0.000000000007981 68.0
WLSH2_k127_5766320_0 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003726 249.0
WLSH2_k127_5766320_1 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000003081 231.0
WLSH2_k127_5766320_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000006091 236.0
WLSH2_k127_5766320_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000001408 181.0
WLSH2_k127_5766320_4 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000006457 184.0
WLSH2_k127_5766320_5 - - - - 0.0000000000000000000000000000000000002999 147.0
WLSH2_k127_5766320_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.000000000000000000000000001891 114.0
WLSH2_k127_5799925_0 Heat shock 70 kDa protein K04043 - - 4.265e-260 814.0
WLSH2_k127_5799925_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 371.0
WLSH2_k127_5799925_2 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.000000000000000000000000000000000000000001421 160.0
WLSH2_k127_5799925_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000002789 114.0
WLSH2_k127_5850227_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 532.0
WLSH2_k127_5850227_1 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 452.0
WLSH2_k127_5850227_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000008044 78.0
WLSH2_k127_5850227_11 Molybdopterin converting factor, small subunit K03636 - - 0.00000001106 59.0
WLSH2_k127_5850227_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 404.0
WLSH2_k127_5850227_3 PFAM PP-loop - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 312.0
WLSH2_k127_5850227_4 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002348 285.0
WLSH2_k127_5850227_5 PFAM TfuA domain protein, core - - - 0.0000000000000000000000000000000000000000000000000000000000000000003908 236.0
WLSH2_k127_5850227_6 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000000002899 176.0
WLSH2_k127_5850227_7 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000001611 136.0
WLSH2_k127_5850227_8 - - - - 0.000000000000000000000000000001239 127.0
WLSH2_k127_5850227_9 - - - - 0.00000000000000000000000004498 115.0
WLSH2_k127_5868872_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 2.977e-201 634.0
WLSH2_k127_5868872_1 transcriptional regulator containing an HTH domain and an K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 378.0
WLSH2_k127_5868872_2 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000008672 105.0
WLSH2_k127_5899277_0 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.0000000000000000000000000000000000000000000000000000000139 221.0
WLSH2_k127_5899277_1 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000004085 187.0
WLSH2_k127_5899277_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000006604 146.0
WLSH2_k127_5899277_3 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000003584 144.0
WLSH2_k127_5899277_4 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000224 111.0
WLSH2_k127_5899277_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.00000000000000004358 84.0
WLSH2_k127_5926882_0 Protein of unknown function, DUF255 K06888 - - 1.613e-224 708.0
WLSH2_k127_5926882_1 PFAM GPR1 FUN34 yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001734 278.0
WLSH2_k127_598322_0 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.00000000000000000000000000000000000000000000000000000000000001035 224.0
WLSH2_k127_598322_1 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000000000000000000000000000000000003156 183.0
WLSH2_k127_598322_2 Cold shock protein K03704 - - 0.00003723 46.0
WLSH2_k127_6054003_0 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 340.0
WLSH2_k127_6054003_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 319.0
WLSH2_k127_6054003_2 Protein of unknown function (DUF2551) - - - 0.00000000000000000000000000000000001765 137.0
WLSH2_k127_6118135_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 584.0
WLSH2_k127_6118135_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 399.0
WLSH2_k127_6118135_2 Met-10+ like-protein K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001463 284.0
WLSH2_k127_6118135_3 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000001529 168.0
WLSH2_k127_6118135_4 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000000008794 154.0
WLSH2_k127_6118135_5 Domain of unknown function (DUF1922) - - - 0.000000003385 61.0
WLSH2_k127_6118135_6 Calcineurin-like phosphoesterase - - - 0.0000002704 62.0
WLSH2_k127_6118135_7 PFAM Pentapeptide repeats (8 copies) - - - 0.0000005626 62.0
WLSH2_k127_6118135_8 Protein of unknown function DUF72 - - - 0.00004934 48.0
WLSH2_k127_6129430_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.063e-194 616.0
WLSH2_k127_6129430_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 588.0
WLSH2_k127_6129430_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 483.0
WLSH2_k127_6129430_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 375.0
WLSH2_k127_6129430_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000004067 238.0
WLSH2_k127_6129430_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000007987 207.0
WLSH2_k127_613436_0 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000004446 106.0
WLSH2_k127_613436_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000001041 90.0
WLSH2_k127_613436_2 conserved protein (DUF2081) - - - 0.000000000000000001163 89.0
WLSH2_k127_613436_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000006731 84.0
WLSH2_k127_6286085_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 387.0
WLSH2_k127_6286085_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 349.0
WLSH2_k127_6286085_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000001655 235.0
WLSH2_k127_6286085_3 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000001545 180.0
WLSH2_k127_6286085_4 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000003405 171.0
WLSH2_k127_6287648_0 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 327.0
WLSH2_k127_6287648_1 Protein of unknown function (DUF499) - - - 0.000000000000000000000000000000000000000000000000000000000001092 218.0
WLSH2_k127_6287648_2 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000002829 128.0
WLSH2_k127_6287648_3 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000008355 115.0
WLSH2_k127_6287648_4 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000002403 55.0
WLSH2_k127_6287648_5 regulation of canonical Wnt signaling pathway involved in osteoblast differentiation - - - 0.0000000241 61.0
WLSH2_k127_6287648_6 addiction module toxin, RelE StbE family K06218 - - 0.0001665 45.0
WLSH2_k127_6287648_7 TIGRFAM CRISPR locus-related DNA-binding protein K07725 - - 0.0002197 47.0
WLSH2_k127_6303825_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 506.0
WLSH2_k127_6303825_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 361.0
WLSH2_k127_6303825_2 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000001928 239.0
WLSH2_k127_6303825_3 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.0000000000000000000000000000000000000000000000000000001253 197.0
WLSH2_k127_6303825_4 Catalyzes the cyclization of 5-formylamidoimidazole-4- carboxamide ribonucleotide to IMP K11176 - 3.5.4.10 0.000000000000000000000000000000000000000000000000001302 189.0
WLSH2_k127_6303825_5 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000012 116.0
WLSH2_k127_6323469_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 360.0
WLSH2_k127_6323469_1 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 314.0
WLSH2_k127_6323469_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 303.0
WLSH2_k127_6323469_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 287.0
WLSH2_k127_6323469_4 binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000001316 139.0
WLSH2_k127_6323469_5 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000126 102.0
WLSH2_k127_6323469_6 Ribosomal protein S27E K02978 - - 0.0000000000000000007561 89.0
WLSH2_k127_6323469_7 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000000005561 78.0
WLSH2_k127_6323469_8 protein conserved in archaea K09723 - - 0.00000000000007295 79.0
WLSH2_k127_6347729_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 396.0
WLSH2_k127_6347729_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000005494 227.0
WLSH2_k127_6347729_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000146 177.0
WLSH2_k127_6425972_0 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000006622 128.0
WLSH2_k127_6425972_1 PFAM DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000000000000006825 126.0
WLSH2_k127_6425972_2 filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000002456 116.0
WLSH2_k127_6425972_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000002635 102.0
WLSH2_k127_6425972_4 mRNA binding - - - 0.0000000000000000003167 89.0
WLSH2_k127_6425972_5 Transposase IS66 family - - - 0.00000000000001589 76.0
WLSH2_k127_643496_0 Permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 468.0
WLSH2_k127_643496_1 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 323.0
WLSH2_k127_643496_2 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.00000000000000000000000000000000001674 140.0
WLSH2_k127_643496_4 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000000419 115.0
WLSH2_k127_643496_5 Pentapeptide repeats (9 copies) - - - 0.000000000007113 76.0
WLSH2_k127_643496_6 - - - - 0.0000006053 55.0
WLSH2_k127_6526909_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 328.0
WLSH2_k127_6526909_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000001114 195.0
WLSH2_k127_6526909_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000007183 158.0
WLSH2_k127_6526909_3 cell wall organization - - - 0.000000000000000000000000000000006255 147.0
WLSH2_k127_6526909_4 but it may be involved in stabilization of the trimeric complex - - - 0.000000000001381 69.0
WLSH2_k127_6526909_5 - - - - 0.00000000005743 69.0
WLSH2_k127_6526909_6 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00000005868 58.0
WLSH2_k127_661152_0 - - - - 1.963e-253 839.0
WLSH2_k127_661152_1 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 492.0
WLSH2_k127_661152_2 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 332.0
WLSH2_k127_661152_3 Rhs element vgr protein K11904 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 320.0
WLSH2_k127_661152_4 - - - - 0.000000000000000000000000000000000000000000000006569 173.0
WLSH2_k127_661152_5 GPW Gp25 family protein - - - 0.00000000000000000000000000000000000000000004532 167.0
WLSH2_k127_6695649_0 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000697 394.0
WLSH2_k127_6695649_1 Cation transport regulator K06197 - - 0.0000000000000009066 80.0
WLSH2_k127_6695649_2 Lamin Tail Domain - - - 0.00000000001629 70.0
WLSH2_k127_6695649_3 - - - - 0.00001584 57.0
WLSH2_k127_6711085_0 glycosyltransferase 36 associated K00702,K13688 - 2.4.1.20 0.0 1528.0
WLSH2_k127_6731496_0 PFAM PilT protein domain protein K06865 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 326.0
WLSH2_k127_6731496_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 322.0
WLSH2_k127_675113_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 342.0
WLSH2_k127_675113_1 Lamin Tail Domain - - - 0.00000002798 64.0
WLSH2_k127_68557_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 567.0
WLSH2_k127_68557_1 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000002365 228.0
WLSH2_k127_68557_2 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.00000000000000000000000001122 113.0
WLSH2_k127_68557_3 PIN domain - - - 0.00000000002195 70.0
WLSH2_k127_685790_0 HEPN domain - - - 0.0000000000000000000000159 102.0
WLSH2_k127_685790_1 DNA polymerase beta palm K07076 - - 0.00000000000000000189 89.0
WLSH2_k127_685790_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000002272 77.0
WLSH2_k127_685790_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000004463 62.0
WLSH2_k127_685790_4 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000003694 61.0
WLSH2_k127_685790_5 Belongs to the acylphosphatase family - - - 0.000186 48.0
WLSH2_k127_6989673_0 PFAM Cache, type 2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000004065 213.0
WLSH2_k127_6989673_1 hydrolase (metallo-beta-lactamase superfamily) - - - 0.0000008146 58.0
WLSH2_k127_6989673_2 - - - - 0.0004768 49.0
WLSH2_k127_7045653_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 2.919e-250 782.0
WLSH2_k127_7045653_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 451.0
WLSH2_k127_7045653_2 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 338.0
WLSH2_k127_7045653_3 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 332.0
WLSH2_k127_7045653_4 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000004733 248.0
WLSH2_k127_7045653_5 Methyl-coenzyme M reductase operon protein D K03422 - - 0.000000000000000000000000000000000008768 142.0
WLSH2_k127_7045653_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000406 109.0
WLSH2_k127_706596_0 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 287.0
WLSH2_k127_706596_1 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000006694 238.0
WLSH2_k127_7070890_0 photosystem II stabilization - - - 1.798e-315 981.0
WLSH2_k127_7070890_1 KH, type 1, domain K07041 - - 2.572e-314 973.0
WLSH2_k127_7070890_10 CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000000000000001484 185.0
WLSH2_k127_7070890_11 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000154 176.0
WLSH2_k127_7070890_12 - - - - 0.0000000000000000000000000000000000000000007241 161.0
WLSH2_k127_7070890_13 Protein of unknown function (DUF1016) - - - 0.0000000000000000000000000000000000003061 141.0
WLSH2_k127_7070890_14 Universal stress protein family - - - 0.0000000000000000000000002948 110.0
WLSH2_k127_7070890_15 Protein of unknown function (DUF1016) - - - 0.0000000000000000000001574 100.0
WLSH2_k127_7070890_16 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000138 94.0
WLSH2_k127_7070890_17 DNA polymerase beta domain protein region - - - 0.0000000000002988 75.0
WLSH2_k127_7070890_18 SpoVT / AbrB like domain - - - 0.000000000001088 70.0
WLSH2_k127_7070890_19 - - - - 0.00000001153 59.0
WLSH2_k127_7070890_2 DEAD DEAH box helicase domain protein K03725 - - 4.872e-221 711.0
WLSH2_k127_7070890_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 415.0
WLSH2_k127_7070890_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 369.0
WLSH2_k127_7070890_5 SMART regulatory protein, Crp K07730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 329.0
WLSH2_k127_7070890_6 nuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001963 271.0
WLSH2_k127_7070890_7 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000105 256.0
WLSH2_k127_7070890_8 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000000000000000000000000000000001478 226.0
WLSH2_k127_7070890_9 Polyprenyl synthetase K02523 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000007072 214.0
WLSH2_k127_7076110_0 histone deacetylase - - - 1.702e-209 659.0
WLSH2_k127_7076110_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 2.537e-205 651.0
WLSH2_k127_7076110_2 PFAM formate nitrite transporter K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 441.0
WLSH2_k127_7076110_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009904 276.0
WLSH2_k127_7076110_4 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000001323 227.0
WLSH2_k127_7076110_5 Hydantoinase/oxoprolinase N-terminal region - - - 0.00000000000000002025 83.0
WLSH2_k127_7145152_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 587.0
WLSH2_k127_7145152_1 Divergent AAA domain protein K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003585 291.0
WLSH2_k127_7145152_2 - - - - 0.000000000000000000000004032 111.0
WLSH2_k127_7145152_3 - - - - 0.00000000000000000002377 101.0
WLSH2_k127_7145152_4 - - - - 0.00000000005829 66.0
WLSH2_k127_7145152_5 - - - - 0.0000000001188 67.0
WLSH2_k127_7145152_6 Tetratricopeptide repeat - - - 0.000001192 57.0
WLSH2_k127_7154757_0 Isocitrate/isopropylmalate dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 575.0
WLSH2_k127_7154757_1 Domain of unknown function (DUF4277) - - - 0.0000000000000000000000000000000003873 134.0
WLSH2_k127_7154757_2 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 K07485 - - 0.0000000000004933 70.0
WLSH2_k127_7154757_3 Domain of unknown function (DUF4277) - - - 0.000000001279 62.0
WLSH2_k127_7154757_4 Domain of unknown function (DUF4277) - - - 0.000000006463 58.0
WLSH2_k127_7154757_5 Rio2, N-terminal K07179 - 2.7.11.1 0.00002354 48.0
WLSH2_k127_7205413_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 625.0
WLSH2_k127_7205413_1 Virulence protein RhuM family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 417.0
WLSH2_k127_7205413_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 361.0
WLSH2_k127_7205413_3 Type I restriction enzyme R protein N terminus (HSDR_N) K01153 - 3.1.21.3 0.000000000000000000000000000001505 123.0
WLSH2_k127_7224783_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 556.0
WLSH2_k127_7224783_1 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 519.0
WLSH2_k127_7224783_2 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 381.0
WLSH2_k127_7224783_3 nucleoside recognition domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003358 231.0
WLSH2_k127_7224783_4 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000002744 150.0
WLSH2_k127_724586_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 381.0
WLSH2_k127_724586_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000002184 107.0
WLSH2_k127_724586_2 TPR Domain containing protein - - - 0.000000000000000000007638 104.0
WLSH2_k127_7327186_0 WD domain, G-beta repeat - - - 4.749e-262 852.0
WLSH2_k127_7327186_1 L COG5421 Transposase - - - 0.000000004259 62.0
WLSH2_k127_7359783_0 - - - - 0.0000000000000000000000000000000000000000004323 162.0
WLSH2_k127_7359783_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000000002434 129.0
WLSH2_k127_7359783_2 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000007016 105.0
WLSH2_k127_7359783_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000002731 104.0
WLSH2_k127_7359783_4 Uncharacterised protein family (UPF0175) - - - 0.00000000000000000000004719 101.0
WLSH2_k127_7359783_5 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000006487 97.0
WLSH2_k127_7359783_6 mRNA binding - - - 0.000000000000000000002608 94.0
WLSH2_k127_7359783_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000004804 94.0
WLSH2_k127_7392461_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 356.0
WLSH2_k127_7392461_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 292.0
WLSH2_k127_7392461_2 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002264 258.0
WLSH2_k127_7392461_3 - - - - 0.000000000000003758 82.0
WLSH2_k127_7392461_4 Belongs to the UPF0216 family K09737 - - 0.00000000000009157 77.0
WLSH2_k127_7392461_5 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000002469 73.0
WLSH2_k127_7406781_0 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 448.0
WLSH2_k127_7406781_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 381.0
WLSH2_k127_7406781_10 Domain of unknown function (DUF4276) - - - 0.00002705 47.0
WLSH2_k127_7406781_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000607 280.0
WLSH2_k127_7406781_3 Domain of unknown function (DUF1890) - - - 0.0000000000000000000000000000000000000000000000000003404 190.0
WLSH2_k127_7406781_4 Domain of unknown function (DUF1894) - - - 0.0000000000000000000000000000000000000000467 154.0
WLSH2_k127_7406781_5 Molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000000000000403 150.0
WLSH2_k127_7406781_6 Radical SAM domain protein - - - 0.00000000000000000000000000000000000001784 151.0
WLSH2_k127_7406781_7 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000001203 82.0
WLSH2_k127_7406781_8 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00000000007634 64.0
WLSH2_k127_7406781_9 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000003843 64.0
WLSH2_k127_7422264_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.551e-271 854.0
WLSH2_k127_7422264_1 Aldo Keto reductase K19265 - - 0.000000000000000001138 85.0
WLSH2_k127_7422264_2 - - - - 0.00007035 49.0
WLSH2_k127_7470430_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 574.0
WLSH2_k127_7470430_1 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 343.0
WLSH2_k127_7470430_2 Protein of unknown function (DUF1699) - - - 0.00000000000000000000000000000000000000000376 160.0
WLSH2_k127_7470430_3 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000002725 76.0
WLSH2_k127_7470430_4 Gar1/Naf1 RNA binding region K07569 - - 0.00000000001551 68.0
WLSH2_k127_7470430_5 Protein of unknown function (DUF1624) - - - 0.0005491 44.0
WLSH2_k127_7476507_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 520.0
WLSH2_k127_7476507_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 354.0
WLSH2_k127_7476507_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 302.0
WLSH2_k127_7476507_3 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 305.0
WLSH2_k127_7476507_4 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000001141 232.0
WLSH2_k127_7476507_5 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000002599 202.0
WLSH2_k127_7476507_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000002198 85.0
WLSH2_k127_74837_0 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 347.0
WLSH2_k127_74837_1 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000001819 106.0
WLSH2_k127_7527654_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1199.0
WLSH2_k127_7527654_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 411.0
WLSH2_k127_7527654_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000004385 151.0
WLSH2_k127_7527654_3 Protein of unknown function (DUF3467) - - - 0.0000000000000000000000000000001342 128.0
WLSH2_k127_7527654_4 Lrp/AsnC ligand binding domain - - - 0.00000000000000001126 84.0
WLSH2_k127_7527654_5 Tetratricopeptide repeat - - - 0.00000000000000004486 90.0
WLSH2_k127_7533852_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 394.0
WLSH2_k127_7533852_1 Belongs to the UPF0212 family K09731 - - 0.00000000000000000000000000000000000000001209 156.0
WLSH2_k127_7533852_2 - - - - 0.000000000000003761 87.0
WLSH2_k127_7534966_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 529.0
WLSH2_k127_7534966_1 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 495.0
WLSH2_k127_7534966_10 Belongs to the acylphosphatase family - - - 0.000000000000000001135 92.0
WLSH2_k127_7534966_11 sugar phosphatases of the HAD superfamily K02566 - - 0.000000000000001269 83.0
WLSH2_k127_7534966_12 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000004682 61.0
WLSH2_k127_7534966_2 Belongs to the UPF0285 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004531 278.0
WLSH2_k127_7534966_3 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000002077 225.0
WLSH2_k127_7534966_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.0000000000000000000000000000000000000001165 164.0
WLSH2_k127_7534966_5 sugar phosphatases of the HAD superfamily K01101,K02566 - 3.1.3.41 0.0000000000000000000000000000000000000002474 156.0
WLSH2_k127_7534966_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000001169 127.0
WLSH2_k127_7534966_7 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000002069 107.0
WLSH2_k127_7534966_8 PFAM TPR repeat-containing protein - - - 0.000000000000000000002305 103.0
WLSH2_k127_7534966_9 Cysteine-rich small domain K08260 - 3.5.1.90 0.0000000000000000001322 100.0
WLSH2_k127_7638790_0 TIGRFAM UbiD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 467.0
WLSH2_k127_7638790_1 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 449.0
WLSH2_k127_7638790_2 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 365.0
WLSH2_k127_7638790_3 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000002781 227.0
WLSH2_k127_7638790_4 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000008388 162.0
WLSH2_k127_7643698_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 333.0
WLSH2_k127_7643698_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002296 237.0
WLSH2_k127_7643698_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000215 115.0
WLSH2_k127_7778953_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009712 263.0
WLSH2_k127_7778953_1 - - - - 0.0000000000000000007797 94.0
WLSH2_k127_7838084_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002769 286.0
WLSH2_k127_7838084_1 COG0500 SAM-dependent methyltransferases K17462 - - 0.00000000000000000000000000000000000000000000000000000002386 204.0
WLSH2_k127_7838084_2 Appr-1'-p processing enzyme - - - 0.0000000000000000000001834 99.0
WLSH2_k127_7838084_3 Pfam:DUF385 - - - 0.0001873 50.0
WLSH2_k127_7861644_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 461.0
WLSH2_k127_7861644_1 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 388.0
WLSH2_k127_7861644_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 362.0
WLSH2_k127_7861644_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000132 157.0
WLSH2_k127_7861644_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000001352 156.0
WLSH2_k127_7861644_5 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000002505 102.0
WLSH2_k127_7861644_6 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000002341 76.0
WLSH2_k127_7918378_0 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 548.0
WLSH2_k127_7918378_1 TPR repeat-containing protein - - - 0.000000000008074 72.0
WLSH2_k127_7919578_0 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000007533 156.0
WLSH2_k127_7919578_1 to PID 1652090 percent identity - - - 0.00000000000000000000000000000006879 129.0
WLSH2_k127_7919578_2 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000000000000005705 98.0
WLSH2_k127_7919578_3 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000007957 69.0
WLSH2_k127_7919578_4 PFAM YcfA-like protein - - - 0.00000000005533 64.0
WLSH2_k127_7919578_5 PIN domain - - - 0.0000005113 57.0
WLSH2_k127_7919578_6 - - - - 0.00008226 45.0
WLSH2_k127_7919578_7 SpoVT / AbrB like domain - - - 0.0007619 44.0
WLSH2_k127_7929579_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 559.0
WLSH2_k127_7929579_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 523.0
WLSH2_k127_7929579_2 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 431.0
WLSH2_k127_7929579_3 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 407.0
WLSH2_k127_7929579_4 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 256.0
WLSH2_k127_7929579_5 - - - - 0.0000000000000000000000000000000000000544 153.0
WLSH2_k127_7929579_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000007321 98.0
WLSH2_k127_7929579_7 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000009727 54.0
WLSH2_k127_7981282_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 458.0
WLSH2_k127_7981282_1 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 298.0
WLSH2_k127_7981282_2 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000831 280.0
WLSH2_k127_7981282_3 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000002236 212.0
WLSH2_k127_7981282_4 - - - - 0.00000000000000000000000000000000003752 143.0
WLSH2_k127_7981282_5 Stress responsive A B barrel domain protein - - - 0.00000000000000000000000003736 110.0
WLSH2_k127_7981282_6 peptidase K08303 - - 0.0000000000000000000000007042 107.0
WLSH2_k127_7981282_7 low-complexity proteins - - - 0.000000000000009609 86.0
WLSH2_k127_7981282_8 - - - - 0.000006736 51.0
WLSH2_k127_8004006_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 388.0
WLSH2_k127_8004006_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000001804 258.0
WLSH2_k127_8004006_2 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.00000000000000000000000000005071 118.0
WLSH2_k127_8004006_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.000000000000000000001565 98.0
WLSH2_k127_8004006_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00583 - 2.1.1.86 0.000000000001636 70.0
WLSH2_k127_8004006_5 TIGRFAM tetrahydromethanopterin S-methyltransferase, F subunit K00582 - 2.1.1.86 0.000000812 53.0
WLSH2_k127_8061559_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004356 554.0
WLSH2_k127_8061559_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 417.0
WLSH2_k127_8061559_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000000009411 240.0
WLSH2_k127_8061559_3 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000000000000000000000000186 195.0
WLSH2_k127_8061559_4 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000000000000000001651 178.0
WLSH2_k127_8061559_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000006071 151.0
WLSH2_k127_8061559_6 Protein of unknown function DUF86 - - - 0.00000000000000000000000237 108.0
WLSH2_k127_8061559_7 nucleotidyltransferase activity K07076 - - 0.0000000006939 66.0
WLSH2_k127_8061559_8 Probable zinc-ribbon domain - - - 0.0002798 45.0
WLSH2_k127_8071602_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 477.0
WLSH2_k127_8071602_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001357 250.0
WLSH2_k127_8096783_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 538.0
WLSH2_k127_8096783_1 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000002363 123.0
WLSH2_k127_8106526_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 434.0
WLSH2_k127_8106526_1 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000001425 198.0
WLSH2_k127_8106526_2 Nicotinamide-nucleotide adenylyltransferase K00952 - 2.7.7.1 0.0000000000000000000000005302 106.0
WLSH2_k127_8106526_3 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000008012 50.0
WLSH2_k127_8116770_0 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000001386 218.0
WLSH2_k127_8116770_1 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000004214 196.0
WLSH2_k127_8116770_2 - - - - 0.00000000000000000005836 94.0
WLSH2_k127_8116770_3 - - - - 0.00000294 52.0
WLSH2_k127_8116770_4 PFAM extracellular solute-binding protein family 3 K02030 - - 0.0005123 43.0
WLSH2_k127_8195703_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 568.0
WLSH2_k127_8195703_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000003428 124.0
WLSH2_k127_8195703_2 Nodulation protein S (NodS) - - - 0.00000005209 63.0
WLSH2_k127_8231614_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 527.0
WLSH2_k127_8231614_1 NAD(P)H dehydrogenase (quinone) K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 287.0
WLSH2_k127_8231614_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000001984 127.0
WLSH2_k127_8294842_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 4.929e-260 815.0
WLSH2_k127_8294842_1 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.000000000000000000000000000000000000000008912 164.0
WLSH2_k127_8294842_2 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000000407 149.0
WLSH2_k127_8294842_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000005135 99.0
WLSH2_k127_8294842_4 sequence-specific DNA binding - - - 0.000000000000000000001167 96.0
WLSH2_k127_8294842_5 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000002456 93.0
WLSH2_k127_8302566_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1056.0
WLSH2_k127_8302566_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000001414 239.0
WLSH2_k127_8302566_2 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000006832 181.0
WLSH2_k127_8302566_3 Thiamine-binding protein - - - 0.0000000000000000001858 91.0
WLSH2_k127_8302566_4 Belongs to the carbamoyltransferase HypF family - - - 0.00001183 49.0
WLSH2_k127_8305412_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002635 268.0
WLSH2_k127_8305412_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000008938 211.0
WLSH2_k127_8305412_10 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.00000000000000000459 91.0
WLSH2_k127_8305412_11 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000000123 87.0
WLSH2_k127_8305412_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000001066 78.0
WLSH2_k127_8305412_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000005134 207.0
WLSH2_k127_8305412_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002713 204.0
WLSH2_k127_8305412_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000005476 200.0
WLSH2_k127_8305412_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000379 186.0
WLSH2_k127_8305412_6 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000000001303 173.0
WLSH2_k127_8305412_7 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000006766 160.0
WLSH2_k127_8305412_8 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000005319 131.0
WLSH2_k127_8305412_9 Belongs to the eukaryotic ribosomal protein eL32 family K02912 - - 0.0000000000000000000000000000938 121.0
WLSH2_k127_8362158_0 dephospho-CoA kinase activity - - - 0.000000000000000000000001707 106.0
WLSH2_k127_8362158_1 PIN domain - - - 0.00000000000008652 78.0
WLSH2_k127_8392954_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 382.0
WLSH2_k127_8392954_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 364.0
WLSH2_k127_8392954_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.00000000000000000003183 93.0
WLSH2_k127_8401599_0 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 399.0
WLSH2_k127_8401599_1 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000000003021 180.0
WLSH2_k127_8401599_2 PAS domain - - - 0.00000000000000000000000000000000000000006866 160.0
WLSH2_k127_8401599_3 - - - - 0.000004196 52.0
WLSH2_k127_8429638_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 504.0
WLSH2_k127_8429638_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 445.0
WLSH2_k127_8429638_10 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000001865 107.0
WLSH2_k127_8429638_11 Pentapeptide repeats (9 copies) - - - 0.0000000000006234 72.0
WLSH2_k127_8429638_12 Pfam:DUF91 K07448,K07503 - - 0.00000948 50.0
WLSH2_k127_8429638_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 360.0
WLSH2_k127_8429638_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 328.0
WLSH2_k127_8429638_4 COG1226 Kef-type K transport systems K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 261.0
WLSH2_k127_8429638_5 Contains one ATP-binding region, ATPase-like domain (IPR003594) K07652 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003674 273.0
WLSH2_k127_8429638_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000001155 232.0
WLSH2_k127_8429638_7 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000003704 176.0
WLSH2_k127_8429638_8 - - - - 0.00000000000000000000000000000001389 132.0
WLSH2_k127_8429638_9 PFAM RDD domain containing protein - - - 0.00000000000000000000000000008736 120.0
WLSH2_k127_843230_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 542.0
WLSH2_k127_843230_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 334.0
WLSH2_k127_843230_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000003245 197.0
WLSH2_k127_843230_3 PFAM PUA domain containing protein K07398 - - 0.00000000000000000000000000000000000000001669 158.0
WLSH2_k127_843230_4 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.00000000000000001766 90.0
WLSH2_k127_843230_5 - - - - 0.0000000000000001291 87.0
WLSH2_k127_843230_6 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0002627 51.0
WLSH2_k127_8509482_0 Required for chromosome condensation and partitioning K03529 - - 2.97e-226 735.0
WLSH2_k127_8509482_1 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 497.0
WLSH2_k127_8509482_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 392.0
WLSH2_k127_8509482_3 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000002142 180.0
WLSH2_k127_8525881_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 567.0
WLSH2_k127_8554541_0 COG0464 ATPases of the AAA class K13525 - - 8.7e-322 999.0
WLSH2_k127_8554541_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 267.0
WLSH2_k127_8554541_2 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000002507 102.0
WLSH2_k127_8554541_3 PFAM PRC-barrel domain - - - 0.000000000000001537 80.0
WLSH2_k127_8554541_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000287 75.0
WLSH2_k127_8575147_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000002748 236.0
WLSH2_k127_8575147_1 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000101 201.0
WLSH2_k127_8575147_2 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000001538 205.0
WLSH2_k127_8583281_0 X-Pro dipeptidyl-peptidase (S15 family) - - - 1.963e-254 801.0
WLSH2_k127_8583281_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 513.0
WLSH2_k127_8583281_2 DJ-1/PfpI family K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000001195 186.0
WLSH2_k127_8583281_3 Protein of unknown function DUF72 - - - 0.000000000000000000002863 96.0
WLSH2_k127_8583281_4 Methanogenesis marker protein 8 - - - 0.0000000000002792 72.0
WLSH2_k127_8583281_5 - - - - 0.00000005012 58.0
WLSH2_k127_8678391_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 303.0
WLSH2_k127_8678391_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.00000000000000000000000000000000000000000000000000006142 202.0
WLSH2_k127_8678391_2 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.0000000000000000000000000000000000003328 148.0
WLSH2_k127_8678391_3 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.0000000000000000000000001023 113.0
WLSH2_k127_8678391_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000000002557 82.0
WLSH2_k127_8678391_5 SEC-C Motif Domain Protein - - - 0.0000000000001814 76.0
WLSH2_k127_8686498_0 Eco57I restriction-modification methylase - - - 0.0 1171.0
WLSH2_k127_8686498_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0 1003.0
WLSH2_k127_8686498_2 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 312.0
WLSH2_k127_8686498_3 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000008356 127.0
WLSH2_k127_8686498_4 PFAM DNA polymerase beta domain protein region K07075 - - 0.000000000000000000009981 95.0
WLSH2_k127_8686498_5 Protein of unknown function (DUF1328) - - - 0.00000008825 55.0
WLSH2_k127_8711611_0 CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 472.0
WLSH2_k127_8711611_1 PFAM 3-demethylubiquinone-9 K04750 - - 0.0000000000000000000000001952 106.0
WLSH2_k127_8711611_2 PFAM nuclease (SNase domain protein) - - - 0.00000000000001717 81.0
WLSH2_k127_8737935_0 CRISPR-associated RAMP protein, Cmr6 family K19142 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 324.0
WLSH2_k127_8737935_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 292.0
WLSH2_k127_8737935_2 RAMP superfamily K09000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001377 271.0
WLSH2_k127_8737935_3 CRISPR-associated protein (Cas_Cmr3) K09127 - - 0.000000000000000000000000000000000000000000000000000001117 203.0
WLSH2_k127_8737935_4 CRISPR-associated protein (Cas_Cmr5) K19141 - - 0.00000000000000000000000004898 111.0
WLSH2_k127_8737935_5 CRISPR-associated protein, APE2256 family - - - 0.00000000000000000000002963 113.0
WLSH2_k127_8737935_6 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000001896 98.0
WLSH2_k127_8737935_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000006415 79.0
WLSH2_k127_8737935_8 TIGRFAM CRISPR-associated protein, Csx3 family K19144 - - 0.0000000000006524 72.0
WLSH2_k127_8789835_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 1.061e-232 739.0
WLSH2_k127_8789835_1 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 339.0
WLSH2_k127_8789835_2 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000001093 128.0
WLSH2_k127_8796332_0 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.00000000002551 68.0
WLSH2_k127_8807590_0 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 616.0
WLSH2_k127_8807590_1 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.00000000000000000000000000006053 118.0
WLSH2_k127_8851552_0 lipopolysaccharide transmembrane transporter activity K07058,K18979 - 1.17.99.6 0.0000000000000000001101 101.0
WLSH2_k127_8851552_1 S-layer protein - - - 0.00000000000000001278 90.0
WLSH2_k127_8851552_2 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000002513 85.0
WLSH2_k127_8851552_3 COG1361 S-layer domain - - - 0.00000003556 57.0
WLSH2_k127_8851552_4 Protein of unknown function (DUF2953) - - - 0.000001723 57.0
WLSH2_k127_8861671_0 DEAD DEAH box helicase domain protein K10896 - - 1.341e-223 717.0
WLSH2_k127_8861671_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 576.0
WLSH2_k127_8861671_10 Cupin domain - - - 0.00000000000000000000002641 103.0
WLSH2_k127_8861671_11 Zn-ribbon containing protein K07163 - - 0.0000000000000000000001925 102.0
WLSH2_k127_8861671_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000002354 62.0
WLSH2_k127_8861671_13 Mo-molybdopterin cofactor metabolic process - - - 0.00005571 47.0
WLSH2_k127_8861671_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 532.0
WLSH2_k127_8861671_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 367.0
WLSH2_k127_8861671_4 GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 314.0
WLSH2_k127_8861671_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000008553 203.0
WLSH2_k127_8861671_6 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.000000000000000000000000000000000004443 139.0
WLSH2_k127_8861671_7 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000001705 126.0
WLSH2_k127_8861671_8 transport system permease K02015 - - 0.00000000000000000000000003559 108.0
WLSH2_k127_8861671_9 PFAM N-6 DNA methylase K03427 - 2.1.1.72 0.0000000000000000000000005376 107.0
WLSH2_k127_8908537_0 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000009663 97.0
WLSH2_k127_8908537_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000002879 98.0
WLSH2_k127_8908537_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000733 96.0
WLSH2_k127_8908537_3 mRNA binding - - - 0.000000000000000000001022 97.0
WLSH2_k127_8908537_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000000000000000000002276 97.0
WLSH2_k127_8908537_5 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000001457 90.0
WLSH2_k127_8908537_6 Domain of unknown function (DUF4258) - - - 0.0000000000000000004593 89.0
WLSH2_k127_8908537_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000007637 82.0
WLSH2_k127_8908537_8 TIGRFAM YgiT-type zinc finger domain - - - 0.0000000000000006085 82.0
WLSH2_k127_8908537_9 mRNA binding - - - 0.000000000008049 69.0
WLSH2_k127_8927618_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.925e-195 628.0
WLSH2_k127_8927618_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 556.0
WLSH2_k127_8927618_10 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000006658 231.0
WLSH2_k127_8927618_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000001152 111.0
WLSH2_k127_8927618_12 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000002394 105.0
WLSH2_k127_8927618_13 Methionine biosynthesis protein MetW - - - 0.000000000000000008678 93.0
WLSH2_k127_8927618_14 Glycosyl transferase 4-like - - - 0.000000000003624 77.0
WLSH2_k127_8927618_15 Glycosyl transferase 4-like domain - - - 0.000000001477 70.0
WLSH2_k127_8927618_16 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000002972 57.0
WLSH2_k127_8927618_17 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.000003196 50.0
WLSH2_k127_8927618_2 Beta-eliminating lyase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 450.0
WLSH2_k127_8927618_3 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 436.0
WLSH2_k127_8927618_4 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 371.0
WLSH2_k127_8927618_5 PFAM oxidoreductase domain protein K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 338.0
WLSH2_k127_8927618_6 MviN-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 314.0
WLSH2_k127_8927618_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001353 279.0
WLSH2_k127_8927618_8 PFAM Bacterial transferase hexapeptide (three repeats) K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001365 272.0
WLSH2_k127_8927618_9 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006957 266.0
WLSH2_k127_8953872_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.013e-277 865.0
WLSH2_k127_8953872_1 COG3387 Glucoamylase and related glycosyl hydrolases - - - 6.421e-248 781.0
WLSH2_k127_8953872_2 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 409.0
WLSH2_k127_8953872_3 Parallel beta-helix repeat K07218 - - 0.00000000000000000000001902 113.0
WLSH2_k127_8990632_0 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
WLSH2_k127_8990632_1 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000000000000000001919 246.0
WLSH2_k127_8990632_2 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000007131 175.0
WLSH2_k127_8990632_3 TIGRFAM precorrin-3B C17-methyltransferase K05934,K13541,K21479 - 2.1.1.131,2.1.1.272,3.7.1.12 0.00000000000000000000000000000000000000253 163.0
WLSH2_k127_8990632_4 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.000000000000000000071 94.0
WLSH2_k127_8990632_5 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.000000000002311 73.0
WLSH2_k127_8990632_6 PFAM nuclease (SNase K01174 - 3.1.31.1 0.0000000009468 70.0
WLSH2_k127_8990632_7 Belongs to the UPF0147 family K09721 - - 0.000000001038 60.0
WLSH2_k127_8994291_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 570.0
WLSH2_k127_8994291_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 435.0
WLSH2_k127_8994291_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 321.0
WLSH2_k127_8994291_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000008082 204.0
WLSH2_k127_8996598_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 406.0
WLSH2_k127_8996598_1 methylisocitrate lyase activity K03417,K20454 - 4.1.3.30,4.1.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 379.0
WLSH2_k127_8996598_2 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000000000000000000000000000000000000000000000000000000008442 224.0
WLSH2_k127_8996598_3 PFAM Aldehyde dehydrogenase K22187 - - 0.00002557 46.0
WLSH2_k127_9008045_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 569.0
WLSH2_k127_9008045_1 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 303.0
WLSH2_k127_9008045_2 Methanogenesis marker protein 5 - - - 0.000000000000000000000000000000000000000000000000000723 186.0
WLSH2_k127_9008045_3 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000172 131.0
WLSH2_k127_9076970_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 456.0
WLSH2_k127_9076970_1 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
WLSH2_k127_9090567_0 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 453.0
WLSH2_k127_9090567_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 377.0
WLSH2_k127_9090567_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000003399 188.0
WLSH2_k127_9090567_3 chlorophyll binding - - - 0.00000000000000000000000000000000000001409 164.0
WLSH2_k127_9090567_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000002108 123.0
WLSH2_k127_9090567_5 - - - - 0.00000000000008476 85.0
WLSH2_k127_913608_0 - - - - 3.065e-229 718.0
WLSH2_k127_913608_1 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 386.0
WLSH2_k127_913608_2 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 339.0
WLSH2_k127_913608_3 PFAM Class II Aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000397 173.0
WLSH2_k127_913608_4 Proprotein convertase P-domain - - - 0.0000000000000000000000000001717 118.0
WLSH2_k127_913608_5 Subtilase family K17734 - - 0.00000000000000000000001421 109.0
WLSH2_k127_9157170_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.775e-284 879.0
WLSH2_k127_9157170_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 577.0
WLSH2_k127_9157170_2 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 323.0
WLSH2_k127_9157170_3 methyltransferase small K07579 - - 0.000000000000000000000000000000000000000000000000000001537 199.0
WLSH2_k127_9157170_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000001676 188.0
WLSH2_k127_9157170_5 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000006376 168.0
WLSH2_k127_9157170_6 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000001313 108.0
WLSH2_k127_9157170_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000005537 86.0
WLSH2_k127_9157170_8 Tetratricopeptide repeat - - - 0.000000000001036 82.0
WLSH2_k127_9176779_0 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000019 105.0
WLSH2_k127_9176779_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000004658 102.0
WLSH2_k127_9176779_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000004702 102.0
WLSH2_k127_9176779_3 mRNA binding - - - 0.0000000000000000001416 91.0
WLSH2_k127_9176779_4 mRNA binding - - - 0.0001171 48.0
WLSH2_k127_9258963_0 helicase superfamily c-terminal domain K07012 - - 1.978e-200 655.0
WLSH2_k127_9258963_1 - K19136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 554.0
WLSH2_k127_9258963_2 CRISPR-associated protein GSU0053 (Cas_GSU0053) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 409.0
WLSH2_k127_9258963_3 PFAM CRISPR-associated protein, GSU0054 K19132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 354.0
WLSH2_k127_9258963_4 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000002067 147.0
WLSH2_k127_9258963_5 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000001389 104.0
WLSH2_k127_9258963_6 Uncharacterised protein family (UPF0175) - - - 0.00000000000000215 79.0
WLSH2_k127_9277931_0 Protein of unknown function (DUF1699) - - - 0.00000000000000000000000000000000000000001265 156.0
WLSH2_k127_9277931_1 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000007574 140.0
WLSH2_k127_9277931_2 Nuclease (SNase domain-containing protein) - - - 0.0000000000000000008844 92.0
WLSH2_k127_9279393_0 von Willebrand factor type A domain K07114 - - 1.303e-194 616.0
WLSH2_k127_9279393_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 574.0
WLSH2_k127_9279393_2 protein involved in tellurite resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 506.0
WLSH2_k127_9325484_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 2.389e-196 625.0
WLSH2_k127_9325484_1 Lamin Tail Domain - - - 0.0000000000000001075 94.0
WLSH2_k127_9430976_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 381.0
WLSH2_k127_9430976_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 356.0
WLSH2_k127_9430976_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001041 242.0
WLSH2_k127_9430976_3 Protein of unknown function DUF126 K09123,K09128 - - 0.000000000000000000000000000000000000004092 151.0
WLSH2_k127_9499341_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 460.0
WLSH2_k127_9499341_1 hydrolase activity, acting on ester bonds K01055 - 3.1.1.24 0.000000000000000000000000004002 115.0
WLSH2_k127_9499341_2 PFAM ABC transporter related K09013 - - 0.0000000001711 62.0
WLSH2_k127_9526183_0 ATP citrate synthase activity K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 1.414e-231 732.0
WLSH2_k127_9526183_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 539.0
WLSH2_k127_9526183_2 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000002854 189.0
WLSH2_k127_9526183_3 ATP-citrate synthase K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.000000000000006426 74.0
WLSH2_k127_9552956_0 PFAM AIR synthase related protein K07388 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 572.0
WLSH2_k127_9552956_1 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 347.0
WLSH2_k127_9552956_10 Transcriptional regulator, TrmB - - - 0.00000000000000000000000002472 113.0
WLSH2_k127_9552956_11 metal ion binding - - - 0.000000000000000000000001805 108.0
WLSH2_k127_9552956_12 Protein of unknown function (DUF2551) - - - 0.0000000000000000002424 91.0
WLSH2_k127_9552956_13 Belongs to the UPF0235 family K09131 - - 0.000000000000000005493 87.0
WLSH2_k127_9552956_14 - - - - 0.00000000000000005967 87.0
WLSH2_k127_9552956_15 COG3420 Nitrous oxidase accessory protein K07218 - - 0.0000000000001091 85.0
WLSH2_k127_9552956_16 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03427 - 2.1.1.72 0.0000000000006473 69.0
WLSH2_k127_9552956_17 Right handed beta helix region - - - 0.0000000435 66.0
WLSH2_k127_9552956_18 Periplasmic copper-binding protein (NosD) - - - 0.000002855 60.0
WLSH2_k127_9552956_2 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 331.0
WLSH2_k127_9552956_3 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 319.0
WLSH2_k127_9552956_4 - - - - 0.00000000000000000000000000000000000000000000000000002684 190.0
WLSH2_k127_9552956_5 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000001935 177.0
WLSH2_k127_9552956_6 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000002308 172.0
WLSH2_k127_9552956_7 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000002402 163.0
WLSH2_k127_9552956_8 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000002935 162.0
WLSH2_k127_9552956_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000004673 160.0
WLSH2_k127_9566040_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 584.0
WLSH2_k127_9566040_1 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 449.0
WLSH2_k127_9566040_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 366.0
WLSH2_k127_9566040_3 cellular potassium ion transport K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 368.0
WLSH2_k127_9566040_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K01719,K01749,K02303,K13542,K13543 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,2.5.1.61,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 327.0
WLSH2_k127_9566040_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 303.0
WLSH2_k127_9566040_6 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 301.0
WLSH2_k127_9566040_7 SMART Elongator protein 3 MiaB NifB K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003108 273.0
WLSH2_k127_9566040_8 Histidine kinase - - - 0.0000000000000000001998 98.0
WLSH2_k127_9566040_9 the current gene model (or a revised gene model) may contain a frame shift K03498 - - 0.00002848 49.0
WLSH2_k127_9568453_0 acid binding OB-fold tRNA helicase-type K07463 - - 1.889e-259 816.0
WLSH2_k127_9568453_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 428.0
WLSH2_k127_9568453_10 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000001097 85.0
WLSH2_k127_9568453_11 FeoA K04758 - - 0.0000000009256 63.0
WLSH2_k127_9568453_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 349.0
WLSH2_k127_9568453_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000551 271.0
WLSH2_k127_9568453_4 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000001215 234.0
WLSH2_k127_9568453_5 ATP-grasp domain K06913 - - 0.0000000000000000000000000000000000000000000000000000000009265 216.0
WLSH2_k127_9568453_6 Ribbon-helix-helix protein, copG family - - - 0.0000000000000000000000000000000000000000000000000000003713 199.0
WLSH2_k127_9568453_7 Transcriptional regulator, TrmB - - - 0.000000000000000000000000000000000006774 141.0
WLSH2_k127_9568453_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000006919 121.0
WLSH2_k127_9568453_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000003866 87.0
WLSH2_k127_9585906_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 446.0
WLSH2_k127_9585906_1 Histidine kinase K14978 - - 0.00001281 53.0
WLSH2_k127_9656092_0 COG2217 Cation transport ATPase K01533 - 3.6.3.4 3.276e-303 942.0
WLSH2_k127_9656092_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 422.0
WLSH2_k127_9656092_2 transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 382.0
WLSH2_k127_9656092_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 350.0
WLSH2_k127_9656092_4 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 354.0
WLSH2_k127_9656092_5 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002523 267.0
WLSH2_k127_9656092_6 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000003479 93.0
WLSH2_k127_9656092_7 extracellular matrix structural constituent - - - 0.000000009561 66.0
WLSH2_k127_9656092_8 protein involved in cytokinesis, contains TGc (transglutaminase protease-like) domain - - - 0.000007971 50.0
WLSH2_k127_9674353_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 544.0
WLSH2_k127_9674353_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 480.0
WLSH2_k127_9674353_2 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000003783 177.0
WLSH2_k127_9676746_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 543.0
WLSH2_k127_9676746_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 417.0
WLSH2_k127_9676746_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 360.0
WLSH2_k127_9676746_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000004325 183.0
WLSH2_k127_9676746_4 Lrp/AsnC ligand binding domain - - - 0.00000000001995 68.0
WLSH2_k127_9688412_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 364.0
WLSH2_k127_9688412_1 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000002713 204.0
WLSH2_k127_9688412_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000003018 174.0
WLSH2_k127_9688412_3 PFAM Aminotransferase class I and II K00812,K10907,K14287 - 2.6.1.1,2.6.1.88 0.0000000000005727 72.0
WLSH2_k127_9688412_4 Restriction endonuclease - - - 0.0000000001278 65.0
WLSH2_k127_9688412_5 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000003025 66.0
WLSH2_k127_97645_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 522.0
WLSH2_k127_97645_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000008839 144.0
WLSH2_k127_97645_2 Belongs to the peptidase S8 family K01400,K01417,K20274 - 3.4.24.28 0.0000000000000000000008502 97.0
WLSH2_k127_97645_3 Mut7-C RNAse domain K09122 - - 0.0000002827 53.0
WLSH2_k127_97645_4 PFAM peptidase - - - 0.00008702 45.0
WLSH2_k127_9803173_0 Belongs to the RtcB family K14415 - 6.5.1.3 9.438e-212 667.0
WLSH2_k127_9803173_1 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 540.0
WLSH2_k127_9803173_2 Superoxide dismutase K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 301.0
WLSH2_k127_9803173_3 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 283.0
WLSH2_k127_9803173_4 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000001015 204.0
WLSH2_k127_9803173_5 - - - - 0.000000000000000000000000000000000000105 145.0
WLSH2_k127_9803173_6 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000000000000000000000000000001551 133.0
WLSH2_k127_9803173_7 Belongs to the 5'(3')-deoxyribonucleotidase family K05967 - - 0.00000000009101 70.0
WLSH2_k127_9803173_8 Periplasmic copper-binding protein (NosD) - - - 0.000000006416 65.0
WLSH2_k127_9804943_0 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 450.0
WLSH2_k127_9804943_1 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 294.0
WLSH2_k127_9804943_2 Belongs to the P(II) protein family K02589,K02590,K04751,K04752 - - 0.000000000000000000000000000001715 124.0
WLSH2_k127_9804943_3 Belongs to the acylphosphatase family - - - 0.0000000000000000004286 93.0
WLSH2_k127_9804943_4 Non-histone chromosomal protein MC1 - - - 0.00000000004978 68.0
WLSH2_k127_9804943_5 Protein of unknown function (DUF1699) - - - 0.000000005287 59.0
WLSH2_k127_9883224_0 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003122 287.0
WLSH2_k127_9883224_1 serine-type peptidase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000008543 231.0
WLSH2_k127_9883224_2 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000005434 162.0
WLSH2_k127_9883224_3 PFAM Protein kinase domain - - - 0.0000000000006396 81.0
WLSH2_k127_9883224_4 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.00000000168 59.0
WLSH2_k127_9946742_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 334.0
WLSH2_k127_9946742_1 Helix-turn-helix domain - - - 0.0000000000000000000000000000001039 129.0
WLSH2_k127_9946742_2 PFAM TonB-dependent Receptor K02014 - - 0.0005136 48.0
WLSH2_k127_9964236_0 CoA binding domain - - - 3.072e-264 830.0
WLSH2_k127_9964236_1 PFAM dihydropteroate synthase, DHPS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 381.0
WLSH2_k127_9964236_2 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002095 269.0
WLSH2_k127_9964236_3 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000001114 104.0
WLSH2_k127_9983704_0 oligoendopeptidase F K08602 - - 9.167e-242 763.0
WLSH2_k127_9983704_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000003332 202.0
WLSH2_k127_9983704_2 - - - - 0.00000000019 62.0
WLSH2_k127_9983704_3 Protein of unknown function (DUF2281) - - - 0.000000005175 60.0