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Overview

ID MAG04238
Name WLSH3_bin.19
Sample SMP0111
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Gallionellaceae
Genus 39-52-133
Species
Assembly information
Completeness (%) 88.3
Contamination (%) 1.46
GC content (%) 53.0
N50 (bp) 26,209
Genome size (bp) 2,709,323

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2607

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH3_k127_10208658_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1333.0
WLSH3_k127_10208658_1 HD domain - - - 1.265e-224 709.0
WLSH3_k127_10208658_10 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000000000000000000000000000000000003734 169.0
WLSH3_k127_10208658_11 Transcriptional regulator K07726 - - 0.000000000000000000000000000000000000008704 147.0
WLSH3_k127_10208658_12 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000004723 111.0
WLSH3_k127_10208658_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000006549 78.0
WLSH3_k127_10208658_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.133e-198 624.0
WLSH3_k127_10208658_3 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 6.681e-196 620.0
WLSH3_k127_10208658_4 Amidohydrolase K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 481.0
WLSH3_k127_10208658_5 ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 460.0
WLSH3_k127_10208658_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
WLSH3_k127_10208658_7 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 299.0
WLSH3_k127_10208658_8 TIGRFAM addiction module killer protein - - - 0.0000000000000000000000000000000000000000000000000005247 185.0
WLSH3_k127_10208658_9 TIGRFAM addiction module antidote protein - - - 0.00000000000000000000000000000000000000000000000002724 181.0
WLSH3_k127_10241660_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 3.016e-222 696.0
WLSH3_k127_10241660_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.461e-214 672.0
WLSH3_k127_10241660_10 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004989 243.0
WLSH3_k127_10241660_11 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000001665 219.0
WLSH3_k127_10241660_12 Belongs to the BolA IbaG family - - - 0.0000000000000000000000004487 107.0
WLSH3_k127_10241660_13 STAS domain K07122 - - 0.00000000000001318 77.0
WLSH3_k127_10241660_2 Sigma-54 interaction domain - - - 1.98e-197 627.0
WLSH3_k127_10241660_3 PFAM type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 595.0
WLSH3_k127_10241660_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 549.0
WLSH3_k127_10241660_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 457.0
WLSH3_k127_10241660_6 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 439.0
WLSH3_k127_10241660_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 361.0
WLSH3_k127_10241660_8 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 302.0
WLSH3_k127_10241660_9 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009859 248.0
WLSH3_k127_10244881_0 PFAM Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0 1076.0
WLSH3_k127_10244881_1 Sucrose synthase K00696 - 2.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 549.0
WLSH3_k127_10244881_2 Chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 377.0
WLSH3_k127_10244881_3 HAD-superfamily hydrolase, subfamily IIB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 336.0
WLSH3_k127_10258727_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 400.0
WLSH3_k127_10258727_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002004 284.0
WLSH3_k127_10301186_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.04e-312 979.0
WLSH3_k127_10301186_1 Glycosyl hydrolase family 57 - - - 1.271e-261 816.0
WLSH3_k127_10301186_10 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02019 - - 0.000000000000000000000000000000006012 132.0
WLSH3_k127_10301186_11 ATP-binding protein K02017 - 3.6.3.29 0.0000000000000000000000001802 108.0
WLSH3_k127_10301186_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.835e-221 692.0
WLSH3_k127_10301186_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 5.397e-203 643.0
WLSH3_k127_10301186_4 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 425.0
WLSH3_k127_10301186_5 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 314.0
WLSH3_k127_10301186_6 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001795 282.0
WLSH3_k127_10301186_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002066 262.0
WLSH3_k127_10301186_8 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000392 221.0
WLSH3_k127_10301186_9 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000001634 199.0
WLSH3_k127_10344320_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.635e-273 856.0
WLSH3_k127_10344320_1 fibronectin type III domain protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 483.0
WLSH3_k127_10344320_2 UTRA K02043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 395.0
WLSH3_k127_10344320_3 Phosphonate ABC transporter K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 353.0
WLSH3_k127_10344320_4 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 323.0
WLSH3_k127_10344320_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 314.0
WLSH3_k127_10348377_0 PAS fold-4 - - - 6.128e-238 773.0
WLSH3_k127_10348377_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 1.64e-205 655.0
WLSH3_k127_10348377_10 TIGRFAM DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 302.0
WLSH3_k127_10348377_11 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 290.0
WLSH3_k127_10348377_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 308.0
WLSH3_k127_10348377_13 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 291.0
WLSH3_k127_10348377_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009025 284.0
WLSH3_k127_10348377_15 Glycosyl hydrolase family 5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000008991 235.0
WLSH3_k127_10348377_16 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000001624 219.0
WLSH3_k127_10348377_17 Protein of unknown function (DUF3485) - - - 0.0000000000000000000000000000000000000000000000000000000005664 209.0
WLSH3_k127_10348377_18 PFAM polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000001658 206.0
WLSH3_k127_10348377_19 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000000000000000004053 197.0
WLSH3_k127_10348377_2 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase, exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 582.0
WLSH3_k127_10348377_20 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000001197 205.0
WLSH3_k127_10348377_21 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000001437 183.0
WLSH3_k127_10348377_22 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001446 156.0
WLSH3_k127_10348377_23 - - - - 0.000000000000000000000000000000000000002075 148.0
WLSH3_k127_10348377_24 Protein of unknown function (DUF2283) - - - 0.000000000000000000000000000002636 120.0
WLSH3_k127_10348377_25 tigrfam pep-cterm - - - 0.00000000000000000000003639 106.0
WLSH3_k127_10348377_26 PEP-CTERM motif - - - 0.00000000000000000000009138 106.0
WLSH3_k127_10348377_27 PEP-CTERM motif - - - 0.000000000000000002513 94.0
WLSH3_k127_10348377_28 - - - - 0.000000001124 63.0
WLSH3_k127_10348377_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 464.0
WLSH3_k127_10348377_4 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 439.0
WLSH3_k127_10348377_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 424.0
WLSH3_k127_10348377_6 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 417.0
WLSH3_k127_10348377_7 Chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 424.0
WLSH3_k127_10348377_8 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 351.0
WLSH3_k127_10348377_9 TIGRFAM peptidyl-prolyl cis-trans isomerase, EpsD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 312.0
WLSH3_k127_10362735_0 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 349.0
WLSH3_k127_10362735_1 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 289.0
WLSH3_k127_10362735_2 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000597 272.0
WLSH3_k127_10362735_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
WLSH3_k127_10362735_4 - - - - 0.00000000000000000000000000000000000000000000000000000000004323 205.0
WLSH3_k127_10362735_5 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.0000000000000000000000000000000000000000000000000000000002951 202.0
WLSH3_k127_10362735_6 SMART helix-turn-helix domain protein K18831 - - 0.00000000000000000000000000000000000000000003386 163.0
WLSH3_k127_10362735_7 cell wall binding repeat 2 - - - 0.0000000002706 70.0
WLSH3_k127_10379574_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1023.0
WLSH3_k127_10379574_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 2.09e-268 840.0
WLSH3_k127_10379574_10 TIGRFAM Addiction module killer protein - - - 0.000000000000000000000000000004033 121.0
WLSH3_k127_10379574_11 Pfam:DUF1049 K08992 - - 0.000000000000000000000000004166 112.0
WLSH3_k127_10379574_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 567.0
WLSH3_k127_10379574_3 Pyridoxal-phosphate dependent enzyme K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 548.0
WLSH3_k127_10379574_4 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 539.0
WLSH3_k127_10379574_5 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 506.0
WLSH3_k127_10379574_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 444.0
WLSH3_k127_10379574_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 362.0
WLSH3_k127_10379574_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000002692 173.0
WLSH3_k127_10379574_9 addiction module antidote protein - - - 0.0000000000000000000000000000000000001825 142.0
WLSH3_k127_10383134_0 Hsp70 protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1095.0
WLSH3_k127_10383134_1 Zn-dependent protease with chaperone function - - - 0.0 1066.0
WLSH3_k127_10383134_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 3.856e-201 629.0
WLSH3_k127_10383134_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.058e-196 617.0
WLSH3_k127_10383134_12 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 584.0
WLSH3_k127_10383134_13 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 584.0
WLSH3_k127_10383134_14 Poly-beta-1,6-N-acetyl-D-glucosamine synthase K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 567.0
WLSH3_k127_10383134_15 Diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 575.0
WLSH3_k127_10383134_16 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 550.0
WLSH3_k127_10383134_17 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 511.0
WLSH3_k127_10383134_18 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 434.0
WLSH3_k127_10383134_19 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 408.0
WLSH3_k127_10383134_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.488e-282 872.0
WLSH3_k127_10383134_20 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 383.0
WLSH3_k127_10383134_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 373.0
WLSH3_k127_10383134_22 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 336.0
WLSH3_k127_10383134_23 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 327.0
WLSH3_k127_10383134_24 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 320.0
WLSH3_k127_10383134_25 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 293.0
WLSH3_k127_10383134_26 Belongs to the GbsR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002193 262.0
WLSH3_k127_10383134_27 Extradiol ring-cleavage dioxygenase class III protein subunit B K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007411 265.0
WLSH3_k127_10383134_28 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001066 260.0
WLSH3_k127_10383134_29 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 260.0
WLSH3_k127_10383134_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.429e-257 802.0
WLSH3_k127_10383134_30 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004591 258.0
WLSH3_k127_10383134_31 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009814 240.0
WLSH3_k127_10383134_32 Competence-damaged protein K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000124 226.0
WLSH3_k127_10383134_33 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000008209 224.0
WLSH3_k127_10383134_34 Predicted integral membrane protein (DUF2269) - - - 0.000000000000000000000000000000000000000000000000000000000002642 211.0
WLSH3_k127_10383134_35 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.00000000000000000000000000000000000000000000002725 179.0
WLSH3_k127_10383134_36 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000106 172.0
WLSH3_k127_10383134_37 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000001588 162.0
WLSH3_k127_10383134_38 Sporulation related domain K03749 - - 0.000000000000000000000000000000000000000001622 164.0
WLSH3_k127_10383134_39 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000953 158.0
WLSH3_k127_10383134_4 Threonine synthase N terminus K01733 - 4.2.3.1 3.58e-249 775.0
WLSH3_k127_10383134_40 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000001613 131.0
WLSH3_k127_10383134_41 CDGSH-type zinc finger. Function unknown. - - - 0.000000000000000000000000000002663 121.0
WLSH3_k127_10383134_42 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000001121 120.0
WLSH3_k127_10383134_44 cellulose binding - - - 0.000000000000000000001189 104.0
WLSH3_k127_10383134_45 DoxX-like family - - - 0.000000000000000000107 95.0
WLSH3_k127_10383134_47 EAL domain K21024 - 3.1.4.52 0.0001546 46.0
WLSH3_k127_10383134_5 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 4.466e-245 761.0
WLSH3_k127_10383134_6 Homoserine dehydrogenase K00003 - 1.1.1.3 3.348e-243 755.0
WLSH3_k127_10383134_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 3.802e-241 747.0
WLSH3_k127_10383134_8 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 3.138e-211 662.0
WLSH3_k127_10383134_9 pilus assembly protein FimV K08086 - - 6.51e-204 668.0
WLSH3_k127_10504454_0 AAA domain K16898 - 3.6.4.12 0.0 1125.0
WLSH3_k127_10504454_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1045.0
WLSH3_k127_10504454_10 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 341.0
WLSH3_k127_10504454_11 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 332.0
WLSH3_k127_10504454_12 Diguanylate cyclase phosphodiesterase (GGDEF EAL domains) with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007136 282.0
WLSH3_k127_10504454_13 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 241.0
WLSH3_k127_10504454_14 Thioesterase K18700 - 3.1.2.29 0.000000000000000000000000000000000000000000000000000000000000000000001463 239.0
WLSH3_k127_10504454_15 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000002002 207.0
WLSH3_k127_10504454_16 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000004367 191.0
WLSH3_k127_10504454_17 Anion-transporting ATPase K03496 - - 0.00000000000000000000000000000000000000000000001759 179.0
WLSH3_k127_10504454_18 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000000000000001646 166.0
WLSH3_k127_10504454_19 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000003937 152.0
WLSH3_k127_10504454_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 1.845e-311 978.0
WLSH3_k127_10504454_20 CheC-like family K03409 - - 0.000000000000000000000000000000002821 134.0
WLSH3_k127_10504454_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 600.0
WLSH3_k127_10504454_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 595.0
WLSH3_k127_10504454_5 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 478.0
WLSH3_k127_10504454_6 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 472.0
WLSH3_k127_10504454_7 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 478.0
WLSH3_k127_10504454_8 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 459.0
WLSH3_k127_10504454_9 Histidine kinase K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 447.0
WLSH3_k127_10512263_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 552.0
WLSH3_k127_10512263_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 549.0
WLSH3_k127_10512263_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000003532 157.0
WLSH3_k127_10586412_0 2-oxoglutarate dehydrogenase N-terminus K00164 - 1.2.4.2 0.0 1441.0
WLSH3_k127_10586412_1 DNA helicase - - - 0.0 1151.0
WLSH3_k127_10586412_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 355.0
WLSH3_k127_10586412_11 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000000000009695 100.0
WLSH3_k127_10586412_13 Helix-turn-helix domain - - - 0.000000000000000000059 91.0
WLSH3_k127_10586412_14 - - - - 0.0000001632 53.0
WLSH3_k127_10586412_15 - - - - 0.0000003439 52.0
WLSH3_k127_10586412_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.168e-243 754.0
WLSH3_k127_10586412_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 596.0
WLSH3_k127_10586412_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 548.0
WLSH3_k127_10586412_5 Methyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 501.0
WLSH3_k127_10586412_6 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 464.0
WLSH3_k127_10586412_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 423.0
WLSH3_k127_10586412_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 426.0
WLSH3_k127_10586412_9 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 375.0
WLSH3_k127_10737305_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 7.004e-263 815.0
WLSH3_k127_10737305_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 8.024e-211 665.0
WLSH3_k127_10737305_10 - - - - 0.0000000004143 63.0
WLSH3_k127_10737305_11 cytochrome oxidase maturation protein cbb3-type - - - 0.000004848 55.0
WLSH3_k127_10737305_12 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.0001125 48.0
WLSH3_k127_10737305_2 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 610.0
WLSH3_k127_10737305_3 Specifically methylates the adenine in position 1618 of 23S rRNA K06970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 383.0
WLSH3_k127_10737305_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 374.0
WLSH3_k127_10737305_5 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 331.0
WLSH3_k127_10737305_6 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000009038 206.0
WLSH3_k127_10737305_7 Heavy metal translocating P-type atpase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000002762 173.0
WLSH3_k127_10737305_8 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000162 139.0
WLSH3_k127_10737305_9 FixH K09926 - - 0.000000000000000005508 91.0
WLSH3_k127_1074963_0 PFAM TrkA-N domain protein K03499 - - 1.829e-235 734.0
WLSH3_k127_1074963_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 429.0
WLSH3_k127_1074963_2 Inositol monophosphatase family K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 387.0
WLSH3_k127_1074963_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 314.0
WLSH3_k127_1074963_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000359 224.0
WLSH3_k127_10788211_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1694.0
WLSH3_k127_10788211_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1156.0
WLSH3_k127_10788211_10 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 447.0
WLSH3_k127_10788211_11 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 401.0
WLSH3_k127_10788211_12 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 370.0
WLSH3_k127_10788211_13 Prokaryotic N-terminal methylation motif K12285 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 304.0
WLSH3_k127_10788211_14 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 286.0
WLSH3_k127_10788211_15 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000001203 259.0
WLSH3_k127_10788211_16 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000007929 224.0
WLSH3_k127_10788211_17 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000004136 211.0
WLSH3_k127_10788211_18 Prokaryotic N-terminal methylation motif K10924 - - 0.00000000000000000000000000000000000000000000000496 178.0
WLSH3_k127_10788211_19 - - - - 0.0000000000000000000000000000000000000000000004472 174.0
WLSH3_k127_10788211_2 General secretory system II protein E domain protein K02454,K02652,K12276 - - 8.802e-300 927.0
WLSH3_k127_10788211_20 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000001266 166.0
WLSH3_k127_10788211_21 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000006654 165.0
WLSH3_k127_10788211_22 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000000000000000000000006096 158.0
WLSH3_k127_10788211_23 general secretion pathway protein K02456,K02457,K02458,K10930,K12285 - - 0.00000000000000000000000000000000000000001416 162.0
WLSH3_k127_10788211_24 - - - - 0.00000000000000000000000000000000000000009613 154.0
WLSH3_k127_10788211_25 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000134 152.0
WLSH3_k127_10788211_26 phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000001903 143.0
WLSH3_k127_10788211_27 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000008497 134.0
WLSH3_k127_10788211_28 Glutaredoxin K03676 - - 0.000000000000000000000000000000001551 131.0
WLSH3_k127_10788211_29 type IV pilus modification protein PilV K10927 - - 0.000000000000000000000000000000006321 135.0
WLSH3_k127_10788211_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 5.847e-254 791.0
WLSH3_k127_10788211_30 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000000006933 116.0
WLSH3_k127_10788211_31 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000003556 112.0
WLSH3_k127_10788211_32 Tfp pilus assembly protein FimT K10926 - - 0.000000000000000000003216 103.0
WLSH3_k127_10788211_33 Pilus assembly protein PilX K12286 - - 0.00000000000000000001009 98.0
WLSH3_k127_10788211_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.305e-231 722.0
WLSH3_k127_10788211_5 Virulence factor membrane-bound polymerase, C-terminal - - - 9.822e-206 657.0
WLSH3_k127_10788211_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 7.719e-202 658.0
WLSH3_k127_10788211_7 PFAM Type II secretion system F domain K02455,K12278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 606.0
WLSH3_k127_10788211_8 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 555.0
WLSH3_k127_10788211_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 450.0
WLSH3_k127_10828161_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.737e-262 821.0
WLSH3_k127_10828161_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.283e-214 668.0
WLSH3_k127_10828161_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000006895 220.0
WLSH3_k127_10828161_3 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000000249 157.0
WLSH3_k127_10934212_0 Domain of unknown function (DUF3400) - - - 0.0 2192.0
WLSH3_k127_10934212_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1035.0
WLSH3_k127_10934212_10 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 417.0
WLSH3_k127_10934212_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 417.0
WLSH3_k127_10934212_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 401.0
WLSH3_k127_10934212_13 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 394.0
WLSH3_k127_10934212_14 PFAM UBA THIF-type NAD FAD binding protein K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 362.0
WLSH3_k127_10934212_15 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 343.0
WLSH3_k127_10934212_16 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 344.0
WLSH3_k127_10934212_17 Transcriptional regulatory protein, C terminal K07659 GO:0000156,GO:0000160,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0035556,GO:0043565,GO:0044212,GO:0044424,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 320.0
WLSH3_k127_10934212_18 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 295.0
WLSH3_k127_10934212_19 addiction module killer protein - - - 0.000000000000000000000000000000000000000000000000000000000000009782 216.0
WLSH3_k127_10934212_2 MacB-like periplasmic core domain K02004 - - 3.881e-200 630.0
WLSH3_k127_10934212_20 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000001133 221.0
WLSH3_k127_10934212_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000001111 211.0
WLSH3_k127_10934212_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000001123 212.0
WLSH3_k127_10934212_23 Rieske-like [2Fe-2S] domain K05710 - - 0.0000000000000000000000000000000000000000000000000008973 184.0
WLSH3_k127_10934212_24 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001753 187.0
WLSH3_k127_10934212_25 SMART helix-turn-helix domain protein K18831 - - 0.000000000000000000000000000000000000000000000004079 174.0
WLSH3_k127_10934212_26 - - - - 0.00000000000000000000000000000000000000000000001904 175.0
WLSH3_k127_10934212_27 - - - - 0.0000000000000000000000000000000000000000000007058 176.0
WLSH3_k127_10934212_28 Cytochrome C' - - - 0.00000000000000000000000000000000000000000001519 166.0
WLSH3_k127_10934212_29 Glycosyl transferase family, helical bundle domain - - - 0.000000000000000000000000000001802 121.0
WLSH3_k127_10934212_3 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 609.0
WLSH3_k127_10934212_30 PFAM cytochrome c class I K08738 - - 0.00000000000000000000000004697 111.0
WLSH3_k127_10934212_31 PFAM cytochrome c class I K08738 - - 0.00000000000000000000001393 103.0
WLSH3_k127_10934212_32 cytochrome - - - 0.0000000000000000001643 92.0
WLSH3_k127_10934212_33 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.00000000000001436 81.0
WLSH3_k127_10934212_35 - - - - 0.000004834 56.0
WLSH3_k127_10934212_4 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 597.0
WLSH3_k127_10934212_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 534.0
WLSH3_k127_10934212_6 PFAM Flavocytochrome c sulphide dehydrogenase, flavin-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 492.0
WLSH3_k127_10934212_7 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 474.0
WLSH3_k127_10934212_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 461.0
WLSH3_k127_10934212_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 452.0
WLSH3_k127_11001299_0 Putative exonuclease SbcCD, C subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006371 530.0
WLSH3_k127_11001299_1 TIGRFAM addiction module toxin, Txe YoeB family K19158 - - 0.00000000000000000000000000000000000000000000001441 171.0
WLSH3_k127_11001299_2 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.00000000000000000000000000000000000003339 144.0
WLSH3_k127_1102526_0 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 549.0
WLSH3_k127_1102526_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 542.0
WLSH3_k127_1102526_10 Smr domain - - - 0.000000000000000000000000000000000000000000000003934 177.0
WLSH3_k127_1102526_11 - - - - 0.0000000000000000000000000000000000000000001355 165.0
WLSH3_k127_1102526_12 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000001695 139.0
WLSH3_k127_1102526_13 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000003662 125.0
WLSH3_k127_1102526_14 Rubredoxin - - - 0.000000000000000000000000006032 109.0
WLSH3_k127_1102526_2 ATPase, AFG1 family K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 490.0
WLSH3_k127_1102526_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 436.0
WLSH3_k127_1102526_4 Transcriptional regulator, LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 399.0
WLSH3_k127_1102526_5 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 392.0
WLSH3_k127_1102526_6 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 383.0
WLSH3_k127_1102526_7 S4 RNA-binding domain K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 290.0
WLSH3_k127_1102526_8 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006719 271.0
WLSH3_k127_1102526_9 NlpC/P60 family K19303 - - 0.000000000000000000000000000000000000000000000001756 177.0
WLSH3_k127_11253965_0 CoA binding domain K09181 - - 0.0 1566.0
WLSH3_k127_11253965_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1552.0
WLSH3_k127_11253965_10 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 5.612e-247 772.0
WLSH3_k127_11253965_11 Abc transporter K02471 - - 1.575e-239 756.0
WLSH3_k127_11253965_12 Amino acid permease - - - 1.752e-239 756.0
WLSH3_k127_11253965_13 signal peptide protein K21006 - - 8.586e-238 764.0
WLSH3_k127_11253965_14 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 2.599e-232 722.0
WLSH3_k127_11253965_15 glycolate oxidase iron-sulfur subunit K11473 - - 3.303e-212 664.0
WLSH3_k127_11253965_16 PFAM Glycosyl transferase, group 1 K21011 - - 4.308e-210 664.0
WLSH3_k127_11253965_17 kinase activity - - - 2.358e-205 646.0
WLSH3_k127_11253965_18 PFAM peptidase S1 and S6 chymotrypsin Hap K04771 - 3.4.21.107 6.396e-196 620.0
WLSH3_k127_11253965_19 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 607.0
WLSH3_k127_11253965_2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0 1202.0
WLSH3_k127_11253965_20 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 567.0
WLSH3_k127_11253965_21 PFAM permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 544.0
WLSH3_k127_11253965_22 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 546.0
WLSH3_k127_11253965_23 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 535.0
WLSH3_k127_11253965_24 PFAM FAD linked oxidase domain protein K00104,K11472 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009933 536.0
WLSH3_k127_11253965_25 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 519.0
WLSH3_k127_11253965_26 membrane protein, terc K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 512.0
WLSH3_k127_11253965_27 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 515.0
WLSH3_k127_11253965_28 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 492.0
WLSH3_k127_11253965_29 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 482.0
WLSH3_k127_11253965_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1082.0
WLSH3_k127_11253965_30 PFAM TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 501.0
WLSH3_k127_11253965_31 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 482.0
WLSH3_k127_11253965_32 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 470.0
WLSH3_k127_11253965_33 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 456.0
WLSH3_k127_11253965_34 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 454.0
WLSH3_k127_11253965_35 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 436.0
WLSH3_k127_11253965_36 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 426.0
WLSH3_k127_11253965_37 PFAM Peptidase S24 S26A S26B, conserved region K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 424.0
WLSH3_k127_11253965_38 SMART chemotaxis sensory transducer - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 426.0
WLSH3_k127_11253965_39 HELICc2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 406.0
WLSH3_k127_11253965_4 Bacterial protein of unknown function (DUF839) K07093 - - 1.838e-312 977.0
WLSH3_k127_11253965_40 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 406.0
WLSH3_k127_11253965_41 COG2202 FOG PAS PAC domain K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 407.0
WLSH3_k127_11253965_42 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 386.0
WLSH3_k127_11253965_43 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 384.0
WLSH3_k127_11253965_44 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 381.0
WLSH3_k127_11253965_45 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 357.0
WLSH3_k127_11253965_46 MucB/RseB C-terminal domain K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 351.0
WLSH3_k127_11253965_47 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 344.0
WLSH3_k127_11253965_48 TIGRFAM RNA polymerase sigma factor RpoE K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 337.0
WLSH3_k127_11253965_49 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 337.0
WLSH3_k127_11253965_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 9.217e-293 902.0
WLSH3_k127_11253965_50 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 325.0
WLSH3_k127_11253965_51 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 325.0
WLSH3_k127_11253965_52 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 332.0
WLSH3_k127_11253965_53 Transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
WLSH3_k127_11253965_54 PFAM nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 290.0
WLSH3_k127_11253965_55 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 285.0
WLSH3_k127_11253965_56 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 282.0
WLSH3_k127_11253965_57 PelD GGDEF domain K21009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001231 276.0
WLSH3_k127_11253965_58 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 258.0
WLSH3_k127_11253965_59 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001988 274.0
WLSH3_k127_11253965_6 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 3.002e-292 902.0
WLSH3_k127_11253965_60 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000001656 241.0
WLSH3_k127_11253965_61 diguanylate cyclase K07216 - - 0.000000000000000000000000000000000000000000000000000000000008164 228.0
WLSH3_k127_11253965_62 Domain of unknown function (DUF1853) K09977 - - 0.00000000000000000000000000000000000000000000000005063 190.0
WLSH3_k127_11253965_63 cAMP biosynthetic process K21008 - - 0.000000000000000000000000000000000000000000000001415 184.0
WLSH3_k127_11253965_64 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000000000000000003277 174.0
WLSH3_k127_11253965_65 transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000002177 176.0
WLSH3_k127_11253965_66 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000002479 169.0
WLSH3_k127_11253965_67 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000003279 166.0
WLSH3_k127_11253965_68 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.00000000000000000000000000000000000000000000414 170.0
WLSH3_k127_11253965_69 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000025 161.0
WLSH3_k127_11253965_7 Metal-dependent hydrolase HDOD - - - 1.72e-266 842.0
WLSH3_k127_11253965_70 Ankyrin repeats (many copies) K10799 - 2.4.2.30 0.000000000000000000000000000000000000000001478 168.0
WLSH3_k127_11253965_71 - - - - 0.000000000000000000000000000000000000000003914 158.0
WLSH3_k127_11253965_72 - - - - 0.00000000000000000000000000000000000000001377 157.0
WLSH3_k127_11253965_73 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000007985 164.0
WLSH3_k127_11253965_74 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000000001547 142.0
WLSH3_k127_11253965_75 Thioredoxin domain - - - 0.000000000000000000000000000000000004796 138.0
WLSH3_k127_11253965_76 PFAM CcdB protein K19163 - - 0.000000000000000000000000000000000006912 138.0
WLSH3_k127_11253965_77 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000008706 130.0
WLSH3_k127_11253965_78 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000000000000000001839 122.0
WLSH3_k127_11253965_79 Domain of unknown function (DUF4845) - - - 0.000000000000000000000000009453 113.0
WLSH3_k127_11253965_8 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.191e-264 830.0
WLSH3_k127_11253965_80 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid K19164 - - 0.000000000000000000000001973 104.0
WLSH3_k127_11253965_81 - - - - 0.000000000000000000000003431 104.0
WLSH3_k127_11253965_82 - - - - 0.0000000000000000000002559 101.0
WLSH3_k127_11253965_83 PFAM Ankyrin K10799 - 2.4.2.30 0.00000000000000000002401 94.0
WLSH3_k127_11253965_84 Tetratricopeptide repeat K21007 - - 0.000000000000000002073 98.0
WLSH3_k127_11253965_85 RDD family - - - 0.000000000000000003118 96.0
WLSH3_k127_11253965_86 spectrin binding - - - 0.00000000000000104 91.0
WLSH3_k127_11253965_87 Prokaryotic diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000001657 81.0
WLSH3_k127_11253965_88 - K19168 - - 0.0000007465 57.0
WLSH3_k127_11253965_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.944e-249 779.0
WLSH3_k127_11343593_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365,K05366 - 2.4.1.129,3.4.16.4 0.0 1253.0
WLSH3_k127_11343593_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 3.432e-235 733.0
WLSH3_k127_11343593_10 Protein of unknown function (DUF3617) - - - 0.000000000000000000000000000000000000000000000000000000000000000003318 238.0
WLSH3_k127_11343593_11 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000008138 199.0
WLSH3_k127_11343593_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K12976,K16079 - - 0.0000000000000000000000000000000000000000000000003422 183.0
WLSH3_k127_11343593_13 photosynthesis K12132,K20543 - 2.7.11.1 0.000000000000000000000000000000000000000000002697 169.0
WLSH3_k127_11343593_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000008521 139.0
WLSH3_k127_11343593_15 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000005836 93.0
WLSH3_k127_11343593_2 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 477.0
WLSH3_k127_11343593_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 449.0
WLSH3_k127_11343593_4 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 374.0
WLSH3_k127_11343593_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 329.0
WLSH3_k127_11343593_6 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
WLSH3_k127_11343593_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 300.0
WLSH3_k127_11343593_8 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 299.0
WLSH3_k127_11343593_9 Protein of unknown function (DUF615) K09889 - - 0.000000000000000000000000000000000000000000000000000000000000000000293 234.0
WLSH3_k127_11403459_0 Likely ribonuclease with RNase H fold. K06959 - - 0.0 1292.0
WLSH3_k127_11403459_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 2.801e-313 964.0
WLSH3_k127_11403459_10 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 267.0
WLSH3_k127_11403459_11 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004634 239.0
WLSH3_k127_11403459_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000001806 221.0
WLSH3_k127_11403459_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000000000002366 146.0
WLSH3_k127_11403459_14 - - - - 0.00000000000000000006234 90.0
WLSH3_k127_11403459_18 - - - - 0.0001847 45.0
WLSH3_k127_11403459_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 7.792e-313 957.0
WLSH3_k127_11403459_3 fad dependent oxidoreductase K07137 - - 1.103e-277 862.0
WLSH3_k127_11403459_4 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.297e-252 783.0
WLSH3_k127_11403459_5 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 6.854e-249 771.0
WLSH3_k127_11403459_6 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 5.056e-209 655.0
WLSH3_k127_11403459_7 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 511.0
WLSH3_k127_11403459_8 AAA domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 380.0
WLSH3_k127_11403459_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 301.0
WLSH3_k127_11408050_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1317.0
WLSH3_k127_11408050_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.0 1257.0
WLSH3_k127_11408050_10 Belongs to the binding-protein-dependent transport system permease family K11961 - - 1.844e-197 621.0
WLSH3_k127_11408050_11 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008573 563.0
WLSH3_k127_11408050_12 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 556.0
WLSH3_k127_11408050_13 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 548.0
WLSH3_k127_11408050_14 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 515.0
WLSH3_k127_11408050_15 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 511.0
WLSH3_k127_11408050_16 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 469.0
WLSH3_k127_11408050_17 TIGRFAM urea ABC transporter, ATP-binding protein UrtD K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 456.0
WLSH3_k127_11408050_18 ABC transporter, ATP-binding protein K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 411.0
WLSH3_k127_11408050_19 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 414.0
WLSH3_k127_11408050_2 AMP-dependent synthetase - - - 0.0 1193.0
WLSH3_k127_11408050_20 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 362.0
WLSH3_k127_11408050_21 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 313.0
WLSH3_k127_11408050_22 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 292.0
WLSH3_k127_11408050_23 chemotaxis, protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008511 281.0
WLSH3_k127_11408050_24 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008237 258.0
WLSH3_k127_11408050_25 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000791 244.0
WLSH3_k127_11408050_26 Ankyrin repeats (many copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
WLSH3_k127_11408050_27 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000114 219.0
WLSH3_k127_11408050_28 Domain of unknown function (DUF1854) - - - 0.000000000000000000000000000000000000000000000000000000000001269 214.0
WLSH3_k127_11408050_29 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000000000000249 192.0
WLSH3_k127_11408050_3 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.0 1088.0
WLSH3_k127_11408050_30 - - - - 0.000000000000000000000000000000000000000000000000003186 184.0
WLSH3_k127_11408050_31 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000001945 175.0
WLSH3_k127_11408050_32 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000008036 175.0
WLSH3_k127_11408050_33 TIGRFAM transcriptional regulator, Rrf2 family K13771 - - 0.0000000000000000000000000000000000000000001323 163.0
WLSH3_k127_11408050_34 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000002092 160.0
WLSH3_k127_11408050_35 - - - - 0.000000000000000000000000000000000000000002276 159.0
WLSH3_k127_11408050_36 regulatory protein, FmdB family - - - 0.00000000000000000000000000000000000006687 145.0
WLSH3_k127_11408050_37 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000006941 95.0
WLSH3_k127_11408050_38 Oxidoreductase FAD-binding domain K14581 - 1.18.1.7 0.00000000000002281 73.0
WLSH3_k127_11408050_39 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 0.000228 46.0
WLSH3_k127_11408050_4 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0 1023.0
WLSH3_k127_11408050_5 TIGRFAM urea ABC transporter, urea binding protein K11959 - - 1.265e-241 750.0
WLSH3_k127_11408050_6 Acetamidase/Formamidase family K01455 - 3.5.1.49 8.985e-229 712.0
WLSH3_k127_11408050_7 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 2.429e-220 694.0
WLSH3_k127_11408050_8 Carbon-nitrogen hydrolase K01426 - 3.5.1.4 5.378e-212 660.0
WLSH3_k127_11408050_9 Oxidoreductase FAD-binding domain protein K00523,K18248 - 1.17.1.1 2.896e-201 637.0
WLSH3_k127_11417413_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1934.0
WLSH3_k127_11417413_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.834e-314 967.0
WLSH3_k127_11417413_10 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000787 233.0
WLSH3_k127_11417413_11 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000000000000000000000000000001049 198.0
WLSH3_k127_11417413_12 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000000000000009327 191.0
WLSH3_k127_11417413_13 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000000000000002927 185.0
WLSH3_k127_11417413_14 - - - - 0.0000000000000000000000000000000000000000000002634 170.0
WLSH3_k127_11417413_15 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000002152 160.0
WLSH3_k127_11417413_16 YaeQ - - - 0.00000000000000000000000000000000000000009415 151.0
WLSH3_k127_11417413_17 Mitomycin resistance protein K07343 - - 0.0000000000000000000000000000005324 124.0
WLSH3_k127_11417413_18 S4 domain K14761 - - 0.000000000000000000000001952 103.0
WLSH3_k127_11417413_19 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000001048 100.0
WLSH3_k127_11417413_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 3.586e-214 681.0
WLSH3_k127_11417413_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 563.0
WLSH3_k127_11417413_4 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 565.0
WLSH3_k127_11417413_5 SPFH domain / Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 438.0
WLSH3_k127_11417413_6 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 414.0
WLSH3_k127_11417413_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 404.0
WLSH3_k127_11417413_8 hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 294.0
WLSH3_k127_11417413_9 Protein of unknown function (DUF1415) K09941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 289.0
WLSH3_k127_115027_0 Alpha amylase, C-terminal all-beta domain K00700 - 2.4.1.18 2.461e-268 829.0
WLSH3_k127_115027_1 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 3.541e-253 786.0
WLSH3_k127_115027_2 FAD dependent oxidoreductase K09471 - - 2.785e-213 669.0
WLSH3_k127_115027_3 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000434 238.0
WLSH3_k127_115027_4 histidine kinase HAMP region domain protein - - - 0.000000002312 59.0
WLSH3_k127_1168284_0 Pilus assembly protein K12279 - - 0.000000000000000000000000000000000000000000000000000000000000000000003193 241.0
WLSH3_k127_1220068_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1620.0
WLSH3_k127_1220068_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0 1255.0
WLSH3_k127_1220068_10 Belongs to the DEAD box helicase family K05591 GO:0000339,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003725,GO:0003729,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006412,GO:0006413,GO:0006518,GO:0006725,GO:0006807,GO:0008026,GO:0008135,GO:0008150,GO:0008152,GO:0008186,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0010501,GO:0016070,GO:0016281,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0042623,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0060255,GO:0065007,GO:0070035,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 3.6.4.13 1.976e-248 772.0
WLSH3_k127_1220068_11 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 1.056e-217 689.0
WLSH3_k127_1220068_12 MacB-like periplasmic core domain K02004 - - 1.473e-202 636.0
WLSH3_k127_1220068_13 RmuC family K09760 - - 8.103e-198 626.0
WLSH3_k127_1220068_14 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 578.0
WLSH3_k127_1220068_15 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 569.0
WLSH3_k127_1220068_16 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 527.0
WLSH3_k127_1220068_17 LapD/MoxY periplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 533.0
WLSH3_k127_1220068_18 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 524.0
WLSH3_k127_1220068_19 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 480.0
WLSH3_k127_1220068_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.0 1106.0
WLSH3_k127_1220068_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 486.0
WLSH3_k127_1220068_21 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 451.0
WLSH3_k127_1220068_22 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 446.0
WLSH3_k127_1220068_23 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 411.0
WLSH3_k127_1220068_24 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 392.0
WLSH3_k127_1220068_25 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 374.0
WLSH3_k127_1220068_26 Tellurite resistance protein TerB K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 374.0
WLSH3_k127_1220068_27 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 375.0
WLSH3_k127_1220068_28 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 363.0
WLSH3_k127_1220068_29 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 353.0
WLSH3_k127_1220068_3 protein synthesis factor, GTP-binding K06207 - - 7.633e-313 966.0
WLSH3_k127_1220068_30 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 319.0
WLSH3_k127_1220068_31 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 305.0
WLSH3_k127_1220068_33 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 293.0
WLSH3_k127_1220068_34 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002613 268.0
WLSH3_k127_1220068_35 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001361 249.0
WLSH3_k127_1220068_36 ATPase involved in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000333 267.0
WLSH3_k127_1220068_37 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000006558 209.0
WLSH3_k127_1220068_38 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000002933 194.0
WLSH3_k127_1220068_39 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000002693 203.0
WLSH3_k127_1220068_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.365e-308 950.0
WLSH3_k127_1220068_40 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000004306 192.0
WLSH3_k127_1220068_41 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.00000000000000000000000000000000000000000000000000000485 207.0
WLSH3_k127_1220068_42 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000001608 180.0
WLSH3_k127_1220068_43 - - - - 0.00000000000000000000000000003662 125.0
WLSH3_k127_1220068_45 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08306 - - 0.00000000000000000000000003875 124.0
WLSH3_k127_1220068_46 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.00000000000000000000000006903 123.0
WLSH3_k127_1220068_47 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000004102 106.0
WLSH3_k127_1220068_48 Heavy metal-associated domain protein K07213 - - 0.000000000000000001025 87.0
WLSH3_k127_1220068_49 Tetratricopeptide repeat - - - 0.000000000000006414 85.0
WLSH3_k127_1220068_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 8.765e-294 917.0
WLSH3_k127_1220068_50 ABC transporter - - - 0.000000000001859 76.0
WLSH3_k127_1220068_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.441e-277 856.0
WLSH3_k127_1220068_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 6.811e-274 850.0
WLSH3_k127_1220068_8 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 5.1e-260 811.0
WLSH3_k127_1220068_9 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.312e-257 799.0
WLSH3_k127_1308894_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 544.0
WLSH3_k127_1308894_1 BRO family, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 394.0
WLSH3_k127_1308894_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000004232 211.0
WLSH3_k127_1308894_3 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.00000000000000000000000000000000000000000000004747 172.0
WLSH3_k127_1308894_4 Helix-turn-helix XRE-family like proteins K07726 - - 0.0000000000000000000000000000002202 124.0
WLSH3_k127_1308894_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000001165 98.0
WLSH3_k127_1308894_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.0000000000003417 69.0
WLSH3_k127_1326370_0 Flavin containing amine oxidoreductase K06954 - - 1.754e-221 692.0
WLSH3_k127_1326370_1 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 4.293e-196 617.0
WLSH3_k127_1326370_2 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 441.0
WLSH3_k127_1326370_3 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 394.0
WLSH3_k127_1326370_4 CbiX K03794 - 4.99.1.4 0.000000000000000000000000000000001635 134.0
WLSH3_k127_1498941_0 PFAM Sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 355.0
WLSH3_k127_1498941_1 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001045 245.0
WLSH3_k127_1498941_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000003656 195.0
WLSH3_k127_1498941_3 oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000000000000001221 190.0
WLSH3_k127_1498941_4 - - - - 0.00000002815 55.0
WLSH3_k127_1498941_5 Citrate transporter - - - 0.0009028 47.0
WLSH3_k127_1510424_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 314.0
WLSH3_k127_1510424_1 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000000000000009564 122.0
WLSH3_k127_1532977_0 divalent heavy-metal cations transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003832 244.0
WLSH3_k127_1532977_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000001946 185.0
WLSH3_k127_1532977_2 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000004697 130.0
WLSH3_k127_1577599_0 PFAM Isocitrate dehydrogenase NADP-dependent monomeric type K00031 - 1.1.1.42 0.0 1237.0
WLSH3_k127_1577599_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1072.0
WLSH3_k127_1577599_10 NUDIX domain K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000000000000003064 220.0
WLSH3_k127_1577599_11 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000000000005554 139.0
WLSH3_k127_1577599_12 PFAM guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.000000000000000000000000000000000006352 140.0
WLSH3_k127_1577599_13 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000003027 136.0
WLSH3_k127_1577599_14 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000000000000000000005787 133.0
WLSH3_k127_1577599_15 Barstar (barnase inhibitor) - - - 0.00000000000000000000000000000001957 130.0
WLSH3_k127_1577599_16 SprA-related family - - - 0.00000000000000000000000000001943 124.0
WLSH3_k127_1577599_17 Regulatory protein, FmdB family - - - 0.000000000000000000000003418 104.0
WLSH3_k127_1577599_18 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000391 105.0
WLSH3_k127_1577599_2 ABC transporter transmembrane region K06147 - - 4.987e-277 862.0
WLSH3_k127_1577599_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 579.0
WLSH3_k127_1577599_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 473.0
WLSH3_k127_1577599_5 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 458.0
WLSH3_k127_1577599_6 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 331.0
WLSH3_k127_1577599_7 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 320.0
WLSH3_k127_1577599_8 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 308.0
WLSH3_k127_1577599_9 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 283.0
WLSH3_k127_1717303_0 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 566.0
WLSH3_k127_1717303_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 397.0
WLSH3_k127_1717303_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005087 281.0
WLSH3_k127_1763881_0 Protein of unknown function (DUF692) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 433.0
WLSH3_k127_1763881_1 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004204 269.0
WLSH3_k127_1763881_2 - - - - 0.0000000000001275 76.0
WLSH3_k127_1845955_0 chemotaxis K03776 - - 0.0000000000000000000000000000000000000000000000000000000002614 218.0
WLSH3_k127_1845955_1 SMART chemotaxis sensory transducer - - - 0.0000000007582 64.0
WLSH3_k127_1860558_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 4.268e-315 977.0
WLSH3_k127_1860558_1 SMART von Willebrand factor type A - - - 2.352e-296 927.0
WLSH3_k127_1860558_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009137 264.0
WLSH3_k127_1860558_11 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004098 269.0
WLSH3_k127_1860558_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
WLSH3_k127_1860558_13 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004717 238.0
WLSH3_k127_1860558_14 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000003312 239.0
WLSH3_k127_1860558_15 - - - - 0.0000000000000007926 79.0
WLSH3_k127_1860558_16 - - - - 0.000000002417 65.0
WLSH3_k127_1860558_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 500.0
WLSH3_k127_1860558_3 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 499.0
WLSH3_k127_1860558_4 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 490.0
WLSH3_k127_1860558_5 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 455.0
WLSH3_k127_1860558_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 402.0
WLSH3_k127_1860558_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 315.0
WLSH3_k127_1860558_8 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 314.0
WLSH3_k127_1860558_9 helix_turn_helix, Lux Regulon K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 285.0
WLSH3_k127_1949855_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.329e-251 777.0
WLSH3_k127_1949855_1 tRNA (guanine-N7-)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 319.0
WLSH3_k127_1949855_2 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 285.0
WLSH3_k127_1949855_3 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000000002627 259.0
WLSH3_k127_1949855_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000008171 234.0
WLSH3_k127_1949855_5 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000000000000000000007909 216.0
WLSH3_k127_1949855_6 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000125 192.0
WLSH3_k127_1949855_7 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000000000005209 179.0
WLSH3_k127_1988203_1 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 289.0
WLSH3_k127_2002257_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1327.0
WLSH3_k127_2002257_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 4.705e-245 762.0
WLSH3_k127_2002257_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 488.0
WLSH3_k127_2002257_11 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 485.0
WLSH3_k127_2002257_12 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 336.0
WLSH3_k127_2002257_13 Belongs to the GbsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002006 265.0
WLSH3_k127_2002257_14 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000003216 184.0
WLSH3_k127_2002257_15 RecX family K03565 - - 0.0000000000000000000000000000000000000000000000001846 180.0
WLSH3_k127_2002257_16 Zinc-finger domain - - - 0.000000000000000000000000000001887 121.0
WLSH3_k127_2002257_17 epimerase dehydratase - - - 0.0000000000000000000001121 98.0
WLSH3_k127_2002257_18 FxsA cytoplasmic membrane protein K07113 - - 0.00000000000000000000241 98.0
WLSH3_k127_2002257_19 TIGRFAM addiction module toxin, RelE StbE family K19092 - - 0.000000000000000000004975 95.0
WLSH3_k127_2002257_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 590.0
WLSH3_k127_2002257_21 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000003022 54.0
WLSH3_k127_2002257_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 579.0
WLSH3_k127_2002257_4 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 565.0
WLSH3_k127_2002257_5 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 532.0
WLSH3_k127_2002257_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 532.0
WLSH3_k127_2002257_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 526.0
WLSH3_k127_2002257_8 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 488.0
WLSH3_k127_2002257_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 484.0
WLSH3_k127_2043534_0 Asparagine synthase K01953 - 6.3.5.4 0.0 1045.0
WLSH3_k127_2043534_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.18e-208 653.0
WLSH3_k127_2043534_2 LemA Family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 312.0
WLSH3_k127_2043534_3 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009812 277.0
WLSH3_k127_2043534_4 transcriptional K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 259.0
WLSH3_k127_2043534_5 TPM domain - - - 0.000000000000000000000000000000000000000000000000000002153 195.0
WLSH3_k127_2083850_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2094.0
WLSH3_k127_2083850_1 Large family of predicted nucleotide-binding domains K07175 - - 2.795e-256 796.0
WLSH3_k127_2083850_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
WLSH3_k127_2083850_11 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000015 298.0
WLSH3_k127_2083850_12 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002547 255.0
WLSH3_k127_2083850_13 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000479 254.0
WLSH3_k127_2083850_14 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001552 247.0
WLSH3_k127_2083850_15 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005987 246.0
WLSH3_k127_2083850_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
WLSH3_k127_2083850_17 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000000000000000007269 222.0
WLSH3_k127_2083850_18 Belongs to the MsrB Met sulfoxide reductase family K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000002141 207.0
WLSH3_k127_2083850_19 YCII-related domain K09780 - - 0.000000000000000000000000000000000000000001658 157.0
WLSH3_k127_2083850_2 - - - - 1.131e-199 623.0
WLSH3_k127_2083850_20 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000005879 157.0
WLSH3_k127_2083850_21 Uncharacterized ACR, COG1993 - - - 0.000000000000000000000000000000004042 130.0
WLSH3_k127_2083850_22 BolA-like protein K05527 - - 0.000000000000000000000000000002805 122.0
WLSH3_k127_2083850_23 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000001995 133.0
WLSH3_k127_2083850_24 Tetratricopeptide repeat protein - - - 0.000000000000000000006 103.0
WLSH3_k127_2083850_25 - K18829 - - 0.000000000000000000006597 93.0
WLSH3_k127_2083850_26 peptidyl-tyrosine sulfation - - - 0.000000000000000000007111 101.0
WLSH3_k127_2083850_27 Lactonase, 7-bladed beta-propeller - - - 0.000000000007751 79.0
WLSH3_k127_2083850_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 609.0
WLSH3_k127_2083850_4 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 387.0
WLSH3_k127_2083850_5 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 377.0
WLSH3_k127_2083850_6 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009375 360.0
WLSH3_k127_2083850_7 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 342.0
WLSH3_k127_2083850_8 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 335.0
WLSH3_k127_2083850_9 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
WLSH3_k127_2107334_0 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.076e-292 905.0
WLSH3_k127_2107334_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000985 525.0
WLSH3_k127_2107334_10 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000002095 101.0
WLSH3_k127_2107334_11 Protein of unknown function (DUF1653) - - - 0.0000000000000000000004375 96.0
WLSH3_k127_2107334_12 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06020 - 3.6.3.25 0.00000000000000002933 82.0
WLSH3_k127_2107334_13 YqjK-like protein - - - 0.0008576 48.0
WLSH3_k127_2107334_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 377.0
WLSH3_k127_2107334_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006098 269.0
WLSH3_k127_2107334_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001217 261.0
WLSH3_k127_2107334_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001559 242.0
WLSH3_k127_2107334_6 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000001055 168.0
WLSH3_k127_2107334_7 proteolysis - - - 0.00000000000000000000000001927 117.0
WLSH3_k127_2107334_8 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000003388 109.0
WLSH3_k127_2124908_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1072.0
WLSH3_k127_2124908_1 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001841 239.0
WLSH3_k127_2124908_2 TIGRFAM succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000000000000002121 179.0
WLSH3_k127_2124908_3 TIGRFAM succinate dehydrogenase, hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000000000004093 161.0
WLSH3_k127_2124908_4 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000000000000000009567 144.0
WLSH3_k127_2124908_5 - - - - 0.0000000000000000000000000000000008819 138.0
WLSH3_k127_2124908_6 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000003547 66.0
WLSH3_k127_2151091_0 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 430.0
WLSH3_k127_2151091_1 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 289.0
WLSH3_k127_2151091_2 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 283.0
WLSH3_k127_2151091_3 Glutathione peroxidase - - - 0.00000000000000000000000000000000000000000000000000000002489 200.0
WLSH3_k127_2175403_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 2.077e-258 802.0
WLSH3_k127_2175403_1 - - - - 0.00000000000000000000000000003199 117.0
WLSH3_k127_2204020_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1110.0
WLSH3_k127_2204020_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1044.0
WLSH3_k127_2204020_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 493.0
WLSH3_k127_2204020_11 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 479.0
WLSH3_k127_2204020_12 Serine Threonine protein K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 447.0
WLSH3_k127_2204020_13 PFAM sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 422.0
WLSH3_k127_2204020_14 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 383.0
WLSH3_k127_2204020_15 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 376.0
WLSH3_k127_2204020_16 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 350.0
WLSH3_k127_2204020_17 histidine kinase HAMP region domain protein K02660,K03406,K13487 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 346.0
WLSH3_k127_2204020_18 Flagellar protein YcgR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 326.0
WLSH3_k127_2204020_19 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 316.0
WLSH3_k127_2204020_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.273e-305 944.0
WLSH3_k127_2204020_20 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
WLSH3_k127_2204020_21 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000007503 235.0
WLSH3_k127_2204020_22 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000001026 231.0
WLSH3_k127_2204020_23 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000000000000002947 196.0
WLSH3_k127_2204020_24 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000005084 208.0
WLSH3_k127_2204020_25 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000006918 187.0
WLSH3_k127_2204020_26 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000006162 170.0
WLSH3_k127_2204020_27 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000006538 160.0
WLSH3_k127_2204020_29 Rhodanese Homology Domain - - - 0.0000000000000000000000000000004435 127.0
WLSH3_k127_2204020_3 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 3.743e-263 816.0
WLSH3_k127_2204020_30 - - - - 0.00000000000000000000000003885 112.0
WLSH3_k127_2204020_31 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000003135 73.0
WLSH3_k127_2204020_4 PFAM multicopper oxidase type K22348 - 1.16.3.3 3.903e-254 785.0
WLSH3_k127_2204020_5 Polyphosphate kinase 2 (PPK2) - - - 4.21e-239 747.0
WLSH3_k127_2204020_6 Glutamate-cysteine ligase K01919 - 6.3.2.2 7.025e-231 719.0
WLSH3_k127_2204020_7 PFAM major facilitator superfamily MFS_1 K08218 - - 1.261e-211 661.0
WLSH3_k127_2204020_8 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 2.287e-206 647.0
WLSH3_k127_2204020_9 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 534.0
WLSH3_k127_2226928_0 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 2.883e-226 707.0
WLSH3_k127_2226928_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 559.0
WLSH3_k127_2226928_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 368.0
WLSH3_k127_2226928_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002086 278.0
WLSH3_k127_2226928_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000764 262.0
WLSH3_k127_2226928_5 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000000000000006428 157.0
WLSH3_k127_2226928_6 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 0.0000000000000000000000003907 106.0
WLSH3_k127_2323086_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 8.874e-212 659.0
WLSH3_k127_2323086_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 385.0
WLSH3_k127_2333960_0 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001026 264.0
WLSH3_k127_2333960_1 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006261 259.0
WLSH3_k127_2333960_2 HDOD domain - - - 0.000000000000000000000000000000000000008367 147.0
WLSH3_k127_2457691_0 B3/4 domain K01890 - 6.1.1.20 0.0 1174.0
WLSH3_k127_2457691_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1074.0
WLSH3_k127_2457691_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 595.0
WLSH3_k127_2457691_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 296.0
WLSH3_k127_2457691_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000002984 206.0
WLSH3_k127_2457691_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000001149 183.0
WLSH3_k127_2457691_6 PFAM regulatory protein MerR - - - 0.0000000000000000000000000000000000000000000008453 168.0
WLSH3_k127_2457691_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000002684 116.0
WLSH3_k127_2510825_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 5.522e-258 799.0
WLSH3_k127_2510825_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.459e-252 785.0
WLSH3_k127_2510825_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 472.0
WLSH3_k127_2510825_11 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 449.0
WLSH3_k127_2510825_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 452.0
WLSH3_k127_2510825_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 430.0
WLSH3_k127_2510825_14 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002182 281.0
WLSH3_k127_2510825_15 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001402 258.0
WLSH3_k127_2510825_16 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003224 263.0
WLSH3_k127_2510825_17 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000001776 211.0
WLSH3_k127_2510825_18 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000003204 135.0
WLSH3_k127_2510825_19 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000000000001783 146.0
WLSH3_k127_2510825_2 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 5.66e-226 706.0
WLSH3_k127_2510825_20 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000001663 83.0
WLSH3_k127_2510825_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.224e-222 694.0
WLSH3_k127_2510825_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 599.0
WLSH3_k127_2510825_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 602.0
WLSH3_k127_2510825_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 594.0
WLSH3_k127_2510825_7 TRAP dicarboxylate transporter, DctM subunit K11690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 582.0
WLSH3_k127_2510825_8 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 557.0
WLSH3_k127_2510825_9 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 512.0
WLSH3_k127_2532740_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.312e-317 978.0
WLSH3_k127_2532740_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 1.046e-209 658.0
WLSH3_k127_2532740_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 324.0
WLSH3_k127_2532740_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002635 268.0
WLSH3_k127_2532740_4 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000001789 221.0
WLSH3_k127_2532740_5 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000007444 175.0
WLSH3_k127_2532740_6 Chemoreceptor zinc-binding domain - - - 0.000000000000000000000000000000000000000000001277 168.0
WLSH3_k127_2532740_7 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000007895 130.0
WLSH3_k127_2694756_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 5.86e-206 647.0
WLSH3_k127_2694756_1 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 497.0
WLSH3_k127_2694756_10 - - - - 0.000000000000000000000000000009214 119.0
WLSH3_k127_2694756_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000001062 92.0
WLSH3_k127_2694756_2 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009146 442.0
WLSH3_k127_2694756_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 403.0
WLSH3_k127_2694756_4 S4 RNA-binding domain K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 383.0
WLSH3_k127_2694756_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 294.0
WLSH3_k127_2694756_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
WLSH3_k127_2694756_7 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002629 257.0
WLSH3_k127_2694756_8 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000000000000000001693 219.0
WLSH3_k127_2694756_9 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000001184 201.0
WLSH3_k127_2706666_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 526.0
WLSH3_k127_2706666_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 457.0
WLSH3_k127_2706666_2 Double sensory domain of two-component sensor kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 430.0
WLSH3_k127_2710403_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 6.663e-278 868.0
WLSH3_k127_2710403_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.206e-259 810.0
WLSH3_k127_2710403_10 SMART CheW domain protein K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 487.0
WLSH3_k127_2710403_11 SMART CheW domain protein K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 473.0
WLSH3_k127_2710403_12 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 467.0
WLSH3_k127_2710403_13 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 464.0
WLSH3_k127_2710403_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 470.0
WLSH3_k127_2710403_15 Two component transcriptional regulator PhoB, winged helix family K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 392.0
WLSH3_k127_2710403_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 341.0
WLSH3_k127_2710403_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 319.0
WLSH3_k127_2710403_18 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 318.0
WLSH3_k127_2710403_19 Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 308.0
WLSH3_k127_2710403_2 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 1.009e-228 724.0
WLSH3_k127_2710403_20 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 306.0
WLSH3_k127_2710403_21 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 306.0
WLSH3_k127_2710403_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003791 275.0
WLSH3_k127_2710403_23 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001372 243.0
WLSH3_k127_2710403_24 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000205 241.0
WLSH3_k127_2710403_25 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000006419 229.0
WLSH3_k127_2710403_26 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000000001017 222.0
WLSH3_k127_2710403_27 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000001871 216.0
WLSH3_k127_2710403_28 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000282 216.0
WLSH3_k127_2710403_29 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000001651 214.0
WLSH3_k127_2710403_3 Signal transducing histidine kinase homodimeric K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 1.111e-219 694.0
WLSH3_k127_2710403_30 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000584 198.0
WLSH3_k127_2710403_31 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000002097 168.0
WLSH3_k127_2710403_32 Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non-flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways K02403 - - 0.0000000000000000000000000000000000000000002178 162.0
WLSH3_k127_2710403_33 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000000265 132.0
WLSH3_k127_2710403_34 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000005782 131.0
WLSH3_k127_2710403_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 8.324e-211 663.0
WLSH3_k127_2710403_5 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 609.0
WLSH3_k127_2710403_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 594.0
WLSH3_k127_2710403_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 570.0
WLSH3_k127_2710403_8 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 551.0
WLSH3_k127_2710403_9 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 513.0
WLSH3_k127_2846676_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0 1024.0
WLSH3_k127_2846676_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 3.407e-296 913.0
WLSH3_k127_2846676_10 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 295.0
WLSH3_k127_2846676_11 penicillin-binding protein K05367 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002767 273.0
WLSH3_k127_2846676_12 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002007 250.0
WLSH3_k127_2846676_13 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001328 234.0
WLSH3_k127_2846676_14 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001214 227.0
WLSH3_k127_2846676_15 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.000000000000000000000000000000000000000000000005879 177.0
WLSH3_k127_2846676_17 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000002097 105.0
WLSH3_k127_2846676_19 Protein of unknown function (DUF2970) - - - 0.0000000007431 61.0
WLSH3_k127_2846676_2 Cytochrome C oxidase subunit II, transmembrane domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 486.0
WLSH3_k127_2846676_3 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 448.0
WLSH3_k127_2846676_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 444.0
WLSH3_k127_2846676_5 Cytochrome c oxidase subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 421.0
WLSH3_k127_2846676_6 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
WLSH3_k127_2846676_7 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 409.0
WLSH3_k127_2846676_8 Histidine Phosphotransfer domain K02488,K11443 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 417.0
WLSH3_k127_2846676_9 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 328.0
WLSH3_k127_2955669_0 alpha-2-macroglobulin domain protein K06894 - - 0.0 2195.0
WLSH3_k127_2955669_1 domain protein K01421 - - 4.55e-217 691.0
WLSH3_k127_2955669_10 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000006629 168.0
WLSH3_k127_2955669_11 - - - - 0.000000000000000000000000000000000000000000005305 171.0
WLSH3_k127_2955669_12 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000003533 150.0
WLSH3_k127_2955669_13 SMART RNA-binding S4 domain protein K04762 - - 0.00000000000000000000000000000000000001314 148.0
WLSH3_k127_2955669_14 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000002105 136.0
WLSH3_k127_2955669_15 - - - - 0.0000000000000000000000009107 111.0
WLSH3_k127_2955669_16 Sel1-like repeats. K07126 - - 0.0000000000000004077 91.0
WLSH3_k127_2955669_18 - - - - 0.00000001516 66.0
WLSH3_k127_2955669_2 penicillin-binding protein K05367 - 2.4.1.129 7.692e-213 679.0
WLSH3_k127_2955669_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 546.0
WLSH3_k127_2955669_4 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 496.0
WLSH3_k127_2955669_5 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 361.0
WLSH3_k127_2955669_6 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 307.0
WLSH3_k127_2955669_7 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000324 290.0
WLSH3_k127_2955669_8 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
WLSH3_k127_2955669_9 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000005233 241.0
WLSH3_k127_3118495_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1705.0
WLSH3_k127_3118495_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 9.774e-277 861.0
WLSH3_k127_3118495_10 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 387.0
WLSH3_k127_3118495_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 382.0
WLSH3_k127_3118495_12 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 356.0
WLSH3_k127_3118495_13 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 335.0
WLSH3_k127_3118495_14 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 319.0
WLSH3_k127_3118495_15 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 313.0
WLSH3_k127_3118495_16 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006695 276.0
WLSH3_k127_3118495_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008516 267.0
WLSH3_k127_3118495_18 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000006731 242.0
WLSH3_k127_3118495_19 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000000000001983 236.0
WLSH3_k127_3118495_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.245e-270 837.0
WLSH3_k127_3118495_20 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
WLSH3_k127_3118495_21 Transglycosylase SLT domain - - - 0.000000000000000000000004429 102.0
WLSH3_k127_3118495_3 DAHP synthetase I family K03856 - 2.5.1.54 2.76e-209 653.0
WLSH3_k127_3118495_4 Sugar (and other) transporter - - - 1.182e-199 632.0
WLSH3_k127_3118495_5 protein conserved in bacteria K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 573.0
WLSH3_k127_3118495_6 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 604.0
WLSH3_k127_3118495_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 565.0
WLSH3_k127_3118495_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 528.0
WLSH3_k127_3118495_9 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 430.0
WLSH3_k127_3162458_0 Peptidase family U32 C-terminal domain K08303 - - 1.911e-262 811.0
WLSH3_k127_3162458_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 563.0
WLSH3_k127_3162458_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 511.0
WLSH3_k127_3162458_3 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 460.0
WLSH3_k127_3162458_4 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 390.0
WLSH3_k127_3162458_5 Domain of unknown function (DUF386) - - - 0.00000000000000000000000000000000000000000000000000000000000005425 216.0
WLSH3_k127_3162458_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000000000000001038 149.0
WLSH3_k127_3162458_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000005511 60.0
WLSH3_k127_3260420_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1252.0
WLSH3_k127_3260420_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.567e-231 728.0
WLSH3_k127_3260420_10 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 429.0
WLSH3_k127_3260420_11 virion core protein (lumpy skin disease virus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 424.0
WLSH3_k127_3260420_12 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 394.0
WLSH3_k127_3260420_13 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 382.0
WLSH3_k127_3260420_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 374.0
WLSH3_k127_3260420_15 NHL repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 319.0
WLSH3_k127_3260420_16 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 311.0
WLSH3_k127_3260420_17 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002932 261.0
WLSH3_k127_3260420_18 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000009731 229.0
WLSH3_k127_3260420_19 Domain of unknown function (DUF4178) - - - 0.000000000000000000000000000000000000000000000000000000000000001398 224.0
WLSH3_k127_3260420_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 2.268e-210 659.0
WLSH3_k127_3260420_20 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000009663 219.0
WLSH3_k127_3260420_21 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000001161 203.0
WLSH3_k127_3260420_22 ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000004337 161.0
WLSH3_k127_3260420_23 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine - - - 0.000000000000000000000000000000000000006402 148.0
WLSH3_k127_3260420_24 PFAM cytochrome c, class I K08738 - - 0.00000000000000000000000000009967 119.0
WLSH3_k127_3260420_25 LPP20 lipoprotein - - - 0.000000000000000000000005569 113.0
WLSH3_k127_3260420_26 Domain of Unknown Function (DUF350) - - - 0.0000000000000000001147 90.0
WLSH3_k127_3260420_27 LPP20 lipoprotein - - - 0.0000000000000000008773 94.0
WLSH3_k127_3260420_28 penicillin binding K05349,K13735 - 3.2.1.21 0.00000000000002496 83.0
WLSH3_k127_3260420_3 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 614.0
WLSH3_k127_3260420_30 - - - - 0.00000000001811 66.0
WLSH3_k127_3260420_31 LPP20 lipoprotein - - - 0.00000001225 65.0
WLSH3_k127_3260420_33 Ankyrin repeat - - - 0.0000008348 62.0
WLSH3_k127_3260420_4 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 603.0
WLSH3_k127_3260420_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 511.0
WLSH3_k127_3260420_6 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 516.0
WLSH3_k127_3260420_7 PFAM aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 483.0
WLSH3_k127_3260420_8 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 461.0
WLSH3_k127_3260420_9 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 455.0
WLSH3_k127_3290852_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1064.0
WLSH3_k127_3290852_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.5e-323 996.0
WLSH3_k127_3290852_10 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 420.0
WLSH3_k127_3290852_11 AAA domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 409.0
WLSH3_k127_3290852_12 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 398.0
WLSH3_k127_3290852_13 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 329.0
WLSH3_k127_3290852_14 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 311.0
WLSH3_k127_3290852_15 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006878 244.0
WLSH3_k127_3290852_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000006638 225.0
WLSH3_k127_3290852_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000000005303 223.0
WLSH3_k127_3290852_18 Antitoxin component of bacterial toxin-antitoxin system, MqsA K13655 - - 0.0000000000000000000000000000000000000000000000000000000000000007095 221.0
WLSH3_k127_3290852_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
WLSH3_k127_3290852_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.304e-297 917.0
WLSH3_k127_3290852_20 PFAM import inner membrane translocase subunit Tim44 - - - 0.0000000000000000000000000000000000000004382 149.0
WLSH3_k127_3290852_21 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000001424 145.0
WLSH3_k127_3290852_22 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000004067 141.0
WLSH3_k127_3290852_23 Motility quorum-sensing regulator, toxin of MqsA K13651 - - 0.000000000000000000000000000000007905 129.0
WLSH3_k127_3290852_24 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001349 109.0
WLSH3_k127_3290852_25 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000001518 105.0
WLSH3_k127_3290852_26 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000004842 81.0
WLSH3_k127_3290852_27 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000631 64.0
WLSH3_k127_3290852_28 ATP synthase I chain K02116 - - 0.000000004754 62.0
WLSH3_k127_3290852_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.615e-274 846.0
WLSH3_k127_3290852_4 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.314e-245 771.0
WLSH3_k127_3290852_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 1.176e-225 710.0
WLSH3_k127_3290852_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 1.436e-219 688.0
WLSH3_k127_3290852_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.489e-213 669.0
WLSH3_k127_3290852_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 2.721e-194 616.0
WLSH3_k127_3290852_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 450.0
WLSH3_k127_3439516_0 SMART CBS domain containing protein K07182 - - 1.221e-235 744.0
WLSH3_k127_3439516_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 312.0
WLSH3_k127_3439516_2 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000005266 216.0
WLSH3_k127_3462419_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 5.867e-227 711.0
WLSH3_k127_3462419_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000000000000000000000000000000000000000000000000000006875 209.0
WLSH3_k127_3462419_2 PIN domain - - - 0.00000000000000000000000000000000000000000000000000000002336 199.0
WLSH3_k127_3462419_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000007873 120.0
WLSH3_k127_3463330_0 Abc transporter K06158 - - 2e-323 998.0
WLSH3_k127_3463330_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 563.0
WLSH3_k127_3463330_2 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005098 255.0
WLSH3_k127_3463330_3 membrane organization K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001846 261.0
WLSH3_k127_3463330_4 Antitoxin component of bacterial toxin-antitoxin system, MqsA K13655 - - 0.000000000000000000000000002702 112.0
WLSH3_k127_3527543_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 6.004e-257 796.0
WLSH3_k127_3527543_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 5.555e-195 612.0
WLSH3_k127_3527543_10 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000000000000000000004783 181.0
WLSH3_k127_3527543_11 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000004301 167.0
WLSH3_k127_3527543_13 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000001744 134.0
WLSH3_k127_3527543_14 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000001316 53.0
WLSH3_k127_3527543_2 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 530.0
WLSH3_k127_3527543_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 496.0
WLSH3_k127_3527543_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 404.0
WLSH3_k127_3527543_5 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 338.0
WLSH3_k127_3527543_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 344.0
WLSH3_k127_3527543_7 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000006697 245.0
WLSH3_k127_3527543_8 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002583 240.0
WLSH3_k127_3527543_9 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000002176 222.0
WLSH3_k127_3619964_0 Ompa motb domain protein - - - 0.0 2132.0
WLSH3_k127_3619964_1 Domain of unknown function DUF11 - - - 0.0 1821.0
WLSH3_k127_3619964_10 LPP20 lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000001256 214.0
WLSH3_k127_3619964_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000186 213.0
WLSH3_k127_3619964_12 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000000000000000000000000000000008547 191.0
WLSH3_k127_3619964_13 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000004535 162.0
WLSH3_k127_3619964_15 FecR protein - - - 0.00000003519 64.0
WLSH3_k127_3619964_2 FtsX-like permease family K02004 - - 0.0 1024.0
WLSH3_k127_3619964_3 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 456.0
WLSH3_k127_3619964_4 Uncharacterised protein family (UPF0160) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 452.0
WLSH3_k127_3619964_5 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 412.0
WLSH3_k127_3619964_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 335.0
WLSH3_k127_3619964_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007473 256.0
WLSH3_k127_3619964_9 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000004654 229.0
WLSH3_k127_3688029_0 Histidine Phosphotransfer domain K02487,K06596 - - 0.0 1740.0
WLSH3_k127_3688029_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1195.0
WLSH3_k127_3688029_10 histidine kinase HAMP region domain protein K02660,K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 594.0
WLSH3_k127_3688029_11 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 559.0
WLSH3_k127_3688029_12 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 550.0
WLSH3_k127_3688029_13 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 532.0
WLSH3_k127_3688029_14 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 464.0
WLSH3_k127_3688029_15 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 404.0
WLSH3_k127_3688029_16 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
WLSH3_k127_3688029_17 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 306.0
WLSH3_k127_3688029_18 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 300.0
WLSH3_k127_3688029_19 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 299.0
WLSH3_k127_3688029_2 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1033.0
WLSH3_k127_3688029_20 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001885 235.0
WLSH3_k127_3688029_21 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000001884 232.0
WLSH3_k127_3688029_22 Two component signalling adaptor domain K02659 - - 0.0000000000000000000000000000000000000000000000000000000000000005538 222.0
WLSH3_k127_3688029_23 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000000000000000000000163 221.0
WLSH3_k127_3688029_24 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000883 205.0
WLSH3_k127_3688029_25 Type IX secretion system membrane protein PorP/SprF - - - 0.00000000000000000000000000000000000000000000000000000006969 212.0
WLSH3_k127_3688029_26 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000001126 188.0
WLSH3_k127_3688029_27 pathogenesis - - - 0.00000000000000000000000000000000000000000000000001791 188.0
WLSH3_k127_3688029_28 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000004216 159.0
WLSH3_k127_3688029_29 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000007654 158.0
WLSH3_k127_3688029_3 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 6.469e-284 876.0
WLSH3_k127_3688029_30 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000000000004164 147.0
WLSH3_k127_3688029_31 Pfam Glutaredoxin - - - 0.00000000000000000000000000000000000002956 149.0
WLSH3_k127_3688029_32 PFAM transposase, IS204 IS1001 IS1096 IS1165 family protein - - - 0.000000000000000000000000000000000002585 142.0
WLSH3_k127_3688029_33 Transposase - - - 0.000000000000000000000000000000000002663 146.0
WLSH3_k127_3688029_34 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000008619 129.0
WLSH3_k127_3688029_35 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000000007816 101.0
WLSH3_k127_3688029_36 transcriptional regulator - - - 0.0000000000000000006948 92.0
WLSH3_k127_3688029_37 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000001193 83.0
WLSH3_k127_3688029_38 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000002153 81.0
WLSH3_k127_3688029_39 Protein of unknown function (DUF1778) - - - 0.0000000000000003027 84.0
WLSH3_k127_3688029_4 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 2.339e-247 769.0
WLSH3_k127_3688029_5 Amidohydrolase family K01465 - 3.5.2.3 6.173e-216 676.0
WLSH3_k127_3688029_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 7.034e-204 637.0
WLSH3_k127_3688029_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 590.0
WLSH3_k127_3688029_8 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 587.0
WLSH3_k127_3688029_9 PFAM aspartate ornithine carbamoyltransferase Asp Orn-binding region K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 581.0
WLSH3_k127_3806376_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 9.541e-242 749.0
WLSH3_k127_3806376_1 Radical SAM superfamily K04069 - 1.97.1.4 7.617e-212 661.0
WLSH3_k127_3806376_10 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 445.0
WLSH3_k127_3806376_11 Short-chain dehydrogenase reductase (SDR) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 403.0
WLSH3_k127_3806376_12 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 397.0
WLSH3_k127_3806376_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 394.0
WLSH3_k127_3806376_14 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 380.0
WLSH3_k127_3806376_15 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 358.0
WLSH3_k127_3806376_16 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 353.0
WLSH3_k127_3806376_17 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 342.0
WLSH3_k127_3806376_18 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 325.0
WLSH3_k127_3806376_19 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005839 317.0
WLSH3_k127_3806376_2 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 617.0
WLSH3_k127_3806376_20 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 310.0
WLSH3_k127_3806376_21 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 313.0
WLSH3_k127_3806376_22 Amino-transferase class IV K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 298.0
WLSH3_k127_3806376_23 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 291.0
WLSH3_k127_3806376_24 Clp protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 278.0
WLSH3_k127_3806376_25 PFAM AMMECR1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001611 267.0
WLSH3_k127_3806376_26 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001813 264.0
WLSH3_k127_3806376_27 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000348 265.0
WLSH3_k127_3806376_28 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001798 255.0
WLSH3_k127_3806376_29 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000002204 183.0
WLSH3_k127_3806376_3 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 604.0
WLSH3_k127_3806376_30 Domain of unknown function (DUF4194) - - - 0.000000000000000000000000000000000000002539 154.0
WLSH3_k127_3806376_31 Addiction module toxin, RelE StbE family - - - 0.000000000000000000000000000000000002239 141.0
WLSH3_k127_3806376_32 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000000000000000327 136.0
WLSH3_k127_3806376_33 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000936 134.0
WLSH3_k127_3806376_34 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000003111 119.0
WLSH3_k127_3806376_35 Putative exonuclease SbcCD, C subunit - - - 0.0000000000000001313 81.0
WLSH3_k127_3806376_36 haloacid dehalogenase-like hydrolase - - - 0.000000000005564 75.0
WLSH3_k127_3806376_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 602.0
WLSH3_k127_3806376_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 549.0
WLSH3_k127_3806376_6 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 533.0
WLSH3_k127_3806376_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 498.0
WLSH3_k127_3806376_8 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 502.0
WLSH3_k127_3806376_9 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 486.0
WLSH3_k127_4019614_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1066.0
WLSH3_k127_4019614_1 Histidine kinase - - - 4.421e-294 951.0
WLSH3_k127_4019614_10 PFAM flagellar motor switch protein FliM K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 458.0
WLSH3_k127_4019614_11 PFAM flagellar basal body FlaE domain protein K02390 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 443.0
WLSH3_k127_4019614_12 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 428.0
WLSH3_k127_4019614_13 flagellar basal-body rod protein FlgG K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 388.0
WLSH3_k127_4019614_14 Bacterial flagellin N-terminal helical region K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 387.0
WLSH3_k127_4019614_15 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 372.0
WLSH3_k127_4019614_16 Plays a role in the flagellum-specific transport system K02419 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 362.0
WLSH3_k127_4019614_17 Belongs to the flagella basal body rod proteins family K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 356.0
WLSH3_k127_4019614_18 PFAM MotA TolQ ExbB proton channel K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 349.0
WLSH3_k127_4019614_19 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 342.0
WLSH3_k127_4019614_2 Periplasmic binding protein domain - - - 9.942e-256 834.0
WLSH3_k127_4019614_20 Bacterial export proteins, family 1 K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 335.0
WLSH3_k127_4019614_21 Cellulose biosynthesis protein BcsQ K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 324.0
WLSH3_k127_4019614_22 response regulator K20977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 324.0
WLSH3_k127_4019614_23 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000011 287.0
WLSH3_k127_4019614_24 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002426 283.0
WLSH3_k127_4019614_25 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000004622 260.0
WLSH3_k127_4019614_26 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000000000000000001323 226.0
WLSH3_k127_4019614_27 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000007481 223.0
WLSH3_k127_4019614_28 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000000000000000000000000000000000000000000212 222.0
WLSH3_k127_4019614_29 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000000005849 207.0
WLSH3_k127_4019614_3 Belongs to the flagella basal body rod proteins family K02396 - - 2.736e-220 701.0
WLSH3_k127_4019614_30 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000007958 198.0
WLSH3_k127_4019614_31 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000001561 192.0
WLSH3_k127_4019614_32 Flagellar motor switch protein FliN K02417,K03225 - - 0.000000000000000000000000000000000000000000001891 169.0
WLSH3_k127_4019614_33 Flagellar hook-length control protein FliK K02414 - - 0.0000000000000000000000000000000000000000005436 164.0
WLSH3_k127_4019614_34 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000000000000000000000003276 141.0
WLSH3_k127_4019614_35 Addiction module toxin, RelE StbE family K07334 - - 0.0000000000000000000000000000000004113 132.0
WLSH3_k127_4019614_36 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000003884 136.0
WLSH3_k127_4019614_37 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000006554 129.0
WLSH3_k127_4019614_38 FlgN protein K02399 - - 0.0000000000000000000000000000001525 128.0
WLSH3_k127_4019614_39 STAS domain K20978 - - 0.0000000000000000000000000137 112.0
WLSH3_k127_4019614_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 3.456e-210 693.0
WLSH3_k127_4019614_40 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000001645 111.0
WLSH3_k127_4019614_41 PFAM Anti-sigma-28 factor FlgM family protein K02398 - - 0.000000000000000000000002609 105.0
WLSH3_k127_4019614_42 flagellar biosynthesis protein K02418 - - 0.0000000000000000000004898 103.0
WLSH3_k127_4019614_43 Flagellar L-ring protein K02393 - - 0.00000000000000000025 96.0
WLSH3_k127_4019614_44 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000003955 58.0
WLSH3_k127_4019614_5 SMART Signal transduction response regulator, receiver region K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 542.0
WLSH3_k127_4019614_6 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 529.0
WLSH3_k127_4019614_7 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 522.0
WLSH3_k127_4019614_8 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 530.0
WLSH3_k127_4019614_9 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 485.0
WLSH3_k127_4264774_0 Cadmium carbonic anhydrase repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 380.0
WLSH3_k127_4264774_1 - - - - 0.0000000000000000000000000000000000000000004294 161.0
WLSH3_k127_4264774_2 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000000000001051 148.0
WLSH3_k127_4264774_3 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000001385 145.0
WLSH3_k127_4264774_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000004065 87.0
WLSH3_k127_4290894_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.425e-316 983.0
WLSH3_k127_4290894_1 MgtE intracellular N domain K06213 - - 1.34e-245 765.0
WLSH3_k127_4290894_10 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 303.0
WLSH3_k127_4290894_11 PFAM ferric-uptake regulator K03711 - - 0.000000000000000000000000000000000000000000000000000000000000001696 222.0
WLSH3_k127_4290894_12 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000004745 183.0
WLSH3_k127_4290894_13 MazG-like family - - - 0.000000000000000000000000000000000000000009225 156.0
WLSH3_k127_4290894_14 PFAM Excinuclease ABC C subunit domain protein K07461 - - 0.00000000000000000000000000000003656 126.0
WLSH3_k127_4290894_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 3.055e-204 643.0
WLSH3_k127_4290894_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.012e-202 642.0
WLSH3_k127_4290894_4 Domain of unknown function DUF21 K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 598.0
WLSH3_k127_4290894_5 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 565.0
WLSH3_k127_4290894_6 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 439.0
WLSH3_k127_4290894_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
WLSH3_k127_4290894_8 Major Facilitator Superfamily K19577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 372.0
WLSH3_k127_4290894_9 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 310.0
WLSH3_k127_4357691_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.519e-295 925.0
WLSH3_k127_4357691_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 468.0
WLSH3_k127_4357691_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 369.0
WLSH3_k127_4357691_3 PFAM MgtC SapB transporter K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 342.0
WLSH3_k127_4357691_4 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 301.0
WLSH3_k127_4357691_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003048 278.0
WLSH3_k127_4357691_6 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000000000000000000000000000001598 169.0
WLSH3_k127_4357691_7 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000004891 138.0
WLSH3_k127_4522595_0 PFAM ABC transporter related - - - 7.758e-297 915.0
WLSH3_k127_4522595_1 Ammonium Transporter Family K03320 - - 7.478e-243 759.0
WLSH3_k127_4522595_10 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002815 267.0
WLSH3_k127_4522595_11 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000000003313 212.0
WLSH3_k127_4522595_12 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000003227 224.0
WLSH3_k127_4522595_13 Alkylphosphonate utilization operon protein PhnA K06193 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000001323 190.0
WLSH3_k127_4522595_15 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000003434 130.0
WLSH3_k127_4522595_16 DsrC like protein K11179 - - 0.0000000000000000000000000000005019 126.0
WLSH3_k127_4522595_17 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00001502 48.0
WLSH3_k127_4522595_2 Malate:quinone oxidoreductase (Mqo) K00116 - 1.1.5.4 2.671e-238 745.0
WLSH3_k127_4522595_3 - - - - 1.225e-236 736.0
WLSH3_k127_4522595_4 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 569.0
WLSH3_k127_4522595_5 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 522.0
WLSH3_k127_4522595_6 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 475.0
WLSH3_k127_4522595_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 353.0
WLSH3_k127_4522595_8 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 314.0
WLSH3_k127_4522595_9 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007262 277.0
WLSH3_k127_4624803_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 419.0
WLSH3_k127_4624803_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000498 284.0
WLSH3_k127_4624803_2 Protein of unknown function (DUF1653) - - - 0.00000000000000000000002276 100.0
WLSH3_k127_462925_0 TIGRFAM glycine oxidase ThiO K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 372.0
WLSH3_k127_462925_1 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 300.0
WLSH3_k127_462925_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000001231 145.0
WLSH3_k127_4745173_0 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 614.0
WLSH3_k127_4745173_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 539.0
WLSH3_k127_4745173_10 ABC transporter, permease protein K02034 - - 0.00000000000000000000000000000000000000000000000003784 189.0
WLSH3_k127_4745173_11 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000001396 179.0
WLSH3_k127_4745173_12 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000001364 149.0
WLSH3_k127_4745173_13 Putative quorum-sensing-regulated virulence factor K09954 - - 0.000000000000000000000000000000001357 130.0
WLSH3_k127_4745173_14 - - - - 0.00000000000000000000002754 103.0
WLSH3_k127_4745173_15 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000007686 96.0
WLSH3_k127_4745173_16 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 - 1.1.1.94 0.000003052 51.0
WLSH3_k127_4745173_17 cell adhesion involved in biofilm formation - - - 0.00003218 57.0
WLSH3_k127_4745173_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 536.0
WLSH3_k127_4745173_3 Belongs to the UPF0354 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 480.0
WLSH3_k127_4745173_4 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 389.0
WLSH3_k127_4745173_5 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 301.0
WLSH3_k127_4745173_6 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 293.0
WLSH3_k127_4745173_7 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 296.0
WLSH3_k127_4745173_8 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003646 277.0
WLSH3_k127_4745173_9 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000141 272.0
WLSH3_k127_4751808_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 4.498e-254 790.0
WLSH3_k127_4751808_1 Sugar (and other) transporter - - - 5.602e-242 757.0
WLSH3_k127_4751808_2 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 603.0
WLSH3_k127_4751808_3 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 458.0
WLSH3_k127_4751808_4 Ribosomal protein L9, N-terminal domain K02939 - - 0.00000000000000000000000000000000000000000000000000000000000000002805 226.0
WLSH3_k127_4751808_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000000000243 221.0
WLSH3_k127_4751808_6 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000003814 182.0
WLSH3_k127_4751808_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000003793 164.0
WLSH3_k127_4751808_8 DNA replication, synthesis of RNA primer K02686 - - 0.000000000000000000000000000002699 122.0
WLSH3_k127_4758579_0 Histidine kinase - - - 4.647e-241 780.0
WLSH3_k127_4758579_1 Glycosyl transferase family, helical bundle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 546.0
WLSH3_k127_4758579_2 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 481.0
WLSH3_k127_4758579_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 362.0
WLSH3_k127_4865395_0 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 592.0
WLSH3_k127_4865395_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 541.0
WLSH3_k127_4865395_2 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 362.0
WLSH3_k127_4865395_3 SOS response K07741,K14623 - - 0.000000000000000000000000000000000000000000000000000000000002881 211.0
WLSH3_k127_4865395_4 DNA-damage-inducible protein d K14623 - - 0.000000000000000000000000000002555 122.0
WLSH3_k127_4865395_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000002054 96.0
WLSH3_k127_4865395_6 SOS response K07741,K14623 - - 0.000000000000001616 78.0
WLSH3_k127_4865395_7 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000004394 53.0
WLSH3_k127_4890779_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 402.0
WLSH3_k127_4890779_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000003824 130.0
WLSH3_k127_4890779_2 Ribbon-helix-helix protein, copG family - - - 0.000000000000000000000001486 104.0
WLSH3_k127_4890779_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000009972 83.0
WLSH3_k127_4890779_4 Deoxynucleoside kinase - - - 0.000000003523 57.0
WLSH3_k127_4946014_0 AAA domain K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 451.0
WLSH3_k127_4946014_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 414.0
WLSH3_k127_4980878_0 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 457.0
WLSH3_k127_4980878_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 438.0
WLSH3_k127_4980878_10 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000002244 214.0
WLSH3_k127_4980878_11 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000006469 194.0
WLSH3_k127_4980878_12 - - - - 0.00000000000000000000000000000000000000000001653 169.0
WLSH3_k127_4980878_13 MerR, DNA binding K08365 - - 0.000000000000000000000000000000000000135 149.0
WLSH3_k127_4980878_14 MerT mercuric transport protein - - - 0.00000000000000000000000000000002584 128.0
WLSH3_k127_4980878_15 Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein K08364 - - 0.0000000000000000000000000007977 115.0
WLSH3_k127_4980878_16 Oxygen tolerance - - - 0.00000000000000000000000002024 124.0
WLSH3_k127_4980878_17 Cytochrome c K17223 - - 0.000000000000000000003175 98.0
WLSH3_k127_4980878_2 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 415.0
WLSH3_k127_4980878_3 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 364.0
WLSH3_k127_4980878_4 PFAM Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 310.0
WLSH3_k127_4980878_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 326.0
WLSH3_k127_4980878_6 von Willebrand factor, type A K07114,K16257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003141 255.0
WLSH3_k127_4980878_7 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002951 243.0
WLSH3_k127_4980878_8 DsrE family K06039 - - 0.00000000000000000000000000000000000000000000000000000000000001162 216.0
WLSH3_k127_4980878_9 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000101 218.0
WLSH3_k127_5089232_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 404.0
WLSH3_k127_5089232_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 286.0
WLSH3_k127_5089232_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000001793 258.0
WLSH3_k127_5089232_3 PFAM import inner membrane translocase subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006494 254.0
WLSH3_k127_5089232_4 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000005086 171.0
WLSH3_k127_5089232_5 Transglycosylase associated protein - - - 0.000000000000000000000000000000006326 128.0
WLSH3_k127_5089232_6 - - - - 0.000000000000000000005206 99.0
WLSH3_k127_5089232_7 - - - - 0.000000273 58.0
WLSH3_k127_5138739_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1202.0
WLSH3_k127_5138739_1 ABC transporter C-terminal domain K15738 - - 1.448e-318 984.0
WLSH3_k127_5138739_10 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000008912 261.0
WLSH3_k127_5138739_11 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002792 259.0
WLSH3_k127_5138739_12 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000003374 186.0
WLSH3_k127_5138739_13 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000000000000000005805 134.0
WLSH3_k127_5138739_14 Thioredoxin-like domain - - - 0.0000000000000000000000000001634 123.0
WLSH3_k127_5138739_15 - - - - 0.000000000000000000000000001641 117.0
WLSH3_k127_5138739_16 - - - - 0.0000000000000000000001052 101.0
WLSH3_k127_5138739_17 - - - - 0.000000000000000002196 86.0
WLSH3_k127_5138739_2 Belongs to the UPF0061 (SELO) family - - - 2.432e-237 741.0
WLSH3_k127_5138739_3 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 575.0
WLSH3_k127_5138739_4 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 548.0
WLSH3_k127_5138739_5 Ferric reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 529.0
WLSH3_k127_5138739_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 518.0
WLSH3_k127_5138739_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 325.0
WLSH3_k127_5138739_8 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 319.0
WLSH3_k127_5138739_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 314.0
WLSH3_k127_5153750_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.75e-310 970.0
WLSH3_k127_5153750_1 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000003072 188.0
WLSH3_k127_5153750_2 - - - - 0.000000000000000000000000000000000000001152 151.0
WLSH3_k127_5153750_3 CheC-like family K03409 - - 0.00000000000000000000000000000003431 133.0
WLSH3_k127_5153750_4 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K00057 - 1.1.1.94 0.00004872 46.0
WLSH3_k127_5240390_0 synthase K01654,K15898 - 2.5.1.56,2.5.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 578.0
WLSH3_k127_5240390_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 557.0
WLSH3_k127_5240390_10 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001154 278.0
WLSH3_k127_5240390_11 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000003512 241.0
WLSH3_k127_5240390_12 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007469 238.0
WLSH3_k127_5240390_13 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.00000000000000000000000000000000000000000001088 173.0
WLSH3_k127_5240390_14 Caenorhabditis protein of unknown function, DUF268 - - - 0.000000000000000115 82.0
WLSH3_k127_5240390_15 Glycosyl transferase, family 2 K16555 - - 0.0000000000001278 81.0
WLSH3_k127_5240390_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 550.0
WLSH3_k127_5240390_3 PFAM ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 558.0
WLSH3_k127_5240390_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 432.0
WLSH3_k127_5240390_5 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 382.0
WLSH3_k127_5240390_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 334.0
WLSH3_k127_5240390_7 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 331.0
WLSH3_k127_5240390_8 Cytidylyltransferase K00983,K15899,K18431 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.43,2.7.7.81,2.7.7.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 295.0
WLSH3_k127_5240390_9 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003277 280.0
WLSH3_k127_5275956_0 Oxidoreductase FAD-binding domain protein K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 566.0
WLSH3_k127_5275956_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 566.0
WLSH3_k127_5275956_11 domain, Protein - - - 0.00000000000000000169 101.0
WLSH3_k127_5275956_2 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 554.0
WLSH3_k127_5275956_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 353.0
WLSH3_k127_5275956_4 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 355.0
WLSH3_k127_5275956_5 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 308.0
WLSH3_k127_5275956_6 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K20755 - 3.4.21.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 335.0
WLSH3_k127_5275956_7 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002368 271.0
WLSH3_k127_5275956_8 Domain of unknown function (DUF4279) - - - 0.00000000000000000000000000000000000000000000000000000000000000008155 224.0
WLSH3_k127_5275956_9 aspartic-type endopeptidase activity K06985 - - 0.000000000000000000000000000000000000000000000000002482 188.0
WLSH3_k127_5329413_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 491.0
WLSH3_k127_5329413_1 Domain of unknown function DUF302 - - - 0.00000000000000002839 82.0
WLSH3_k127_5378511_0 Metal-dependent hydrolase HDOD - - - 4.811e-218 700.0
WLSH3_k127_5378511_1 (ABC) transporter K02056 - 3.6.3.17 2.087e-217 689.0
WLSH3_k127_5378511_10 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 357.0
WLSH3_k127_5378511_11 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 366.0
WLSH3_k127_5378511_12 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009612 256.0
WLSH3_k127_5378511_13 GntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002182 255.0
WLSH3_k127_5378511_14 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001943 253.0
WLSH3_k127_5378511_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007549 232.0
WLSH3_k127_5378511_16 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000003364 220.0
WLSH3_k127_5378511_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000122 228.0
WLSH3_k127_5378511_18 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000000000000000000000000000000000000000000000000000001206 209.0
WLSH3_k127_5378511_19 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000001806 197.0
WLSH3_k127_5378511_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K19837 - 3.5.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 607.0
WLSH3_k127_5378511_20 small multidrug export protein - - - 0.000000000000000000000000000000000000000000000000004948 189.0
WLSH3_k127_5378511_21 Protein of unknown function (DUF3225) - - - 0.0000000000000000000000000000000000000001776 154.0
WLSH3_k127_5378511_22 COGs COG0628 permease - - - 0.00000000000000000009126 98.0
WLSH3_k127_5378511_23 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.000000000000000001084 88.0
WLSH3_k127_5378511_24 Protein of unknown function (DUF4089) - - - 0.000404 47.0
WLSH3_k127_5378511_3 Amidase K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 602.0
WLSH3_k127_5378511_4 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 473.0
WLSH3_k127_5378511_5 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 447.0
WLSH3_k127_5378511_6 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 419.0
WLSH3_k127_5378511_7 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 419.0
WLSH3_k127_5378511_8 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 379.0
WLSH3_k127_5378511_9 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 357.0
WLSH3_k127_5392021_0 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 306.0
WLSH3_k127_5392021_1 chemotaxis, protein K03406 - - 0.000000000000000000000000000000000000004668 149.0
WLSH3_k127_5392021_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000002805 84.0
WLSH3_k127_5392021_3 Alpha/beta hydrolase family - - - 0.000000000000000157 79.0
WLSH3_k127_5400781_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 2.574e-214 672.0
WLSH3_k127_5400781_1 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 4.037e-201 629.0
WLSH3_k127_5400781_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 392.0
WLSH3_k127_5400781_3 TIGRFAM HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 347.0
WLSH3_k127_5400781_4 Bacterial dnaA protein K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 294.0
WLSH3_k127_5400781_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 289.0
WLSH3_k127_5400781_6 PFAM PsiF repeat protein - - - 0.0000000000000000000005424 98.0
WLSH3_k127_5400781_7 Protein of unknown function (DUF3108) - - - 0.00000001195 59.0
WLSH3_k127_5483694_0 Putative diguanylate phosphodiesterase - - - 2.029e-215 681.0
WLSH3_k127_5483694_1 Major facilitator Superfamily K06902 - - 3.793e-209 658.0
WLSH3_k127_5483694_10 - - - - 0.000000000000000000000000000000001416 138.0
WLSH3_k127_5483694_11 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000001164 87.0
WLSH3_k127_5483694_12 Diguanylate cyclase K03320 - - 0.0000000001452 67.0
WLSH3_k127_5483694_13 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000005224 55.0
WLSH3_k127_5483694_2 CHASE2 K01768 - 4.6.1.1 2.371e-201 651.0
WLSH3_k127_5483694_3 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 606.0
WLSH3_k127_5483694_4 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 521.0
WLSH3_k127_5483694_5 Protein of unknown function (DUF1501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 449.0
WLSH3_k127_5483694_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002992 258.0
WLSH3_k127_5483694_7 Glutaredoxin - - - 0.0000000000000000000000000000000000000000000001399 171.0
WLSH3_k127_5483694_8 - - - - 0.0000000000000000000000000000000000000000000003268 175.0
WLSH3_k127_5545079_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1074.0
WLSH3_k127_5545079_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1056.0
WLSH3_k127_5545079_2 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 370.0
WLSH3_k127_5545079_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009255 245.0
WLSH3_k127_5545079_5 Plasmid stabilization system - - - 0.00000000000000000000000000000000000004909 144.0
WLSH3_k127_5545079_6 Putative addiction module component - - - 0.0000000000000000000022 96.0
WLSH3_k127_5545079_7 Domain of unknown function (DUF4160) - - - 0.0000000000000003875 80.0
WLSH3_k127_5545079_8 Post-segregation antitoxin CcdA K19164 - - 0.00001818 50.0
WLSH3_k127_5577064_0 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 302.0
WLSH3_k127_5577064_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 282.0
WLSH3_k127_5577064_2 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000000000000000000000000002613 197.0
WLSH3_k127_5577064_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000002883 158.0
WLSH3_k127_5577064_4 - - - - 0.00000000000000000000000000000000000000003415 160.0
WLSH3_k127_5577064_6 methyltransferase activity - - - 0.000000000000419 75.0
WLSH3_k127_5577064_7 - - - - 0.000000000001542 72.0
WLSH3_k127_5577064_9 - - - - 0.000000005384 58.0
WLSH3_k127_5594551_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.293e-247 767.0
WLSH3_k127_5594551_1 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 507.0
WLSH3_k127_5639291_0 repeat-containing protein - - - 7.504e-258 813.0
WLSH3_k127_5639291_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.915e-250 781.0
WLSH3_k127_5639291_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 418.0
WLSH3_k127_5639291_11 hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 402.0
WLSH3_k127_5639291_12 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 373.0
WLSH3_k127_5639291_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 362.0
WLSH3_k127_5639291_14 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 329.0
WLSH3_k127_5639291_15 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 316.0
WLSH3_k127_5639291_16 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 282.0
WLSH3_k127_5639291_17 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008835 276.0
WLSH3_k127_5639291_18 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000002229 199.0
WLSH3_k127_5639291_19 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000000000001291 180.0
WLSH3_k127_5639291_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.125e-215 670.0
WLSH3_k127_5639291_20 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000000006447 171.0
WLSH3_k127_5639291_21 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000002977 152.0
WLSH3_k127_5639291_22 DNA-binding protein VF530 - - - 0.00000000000000000000000000003435 117.0
WLSH3_k127_5639291_23 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000002344 114.0
WLSH3_k127_5639291_24 cytochrome - - - 0.00000000000000000000000006723 109.0
WLSH3_k127_5639291_25 COG2863 Cytochrome c553 - - - 0.0000000000000000000004512 109.0
WLSH3_k127_5639291_26 Protein of Unknown function (DUF2784) - - - 0.00000002157 56.0
WLSH3_k127_5639291_27 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000001226 64.0
WLSH3_k127_5639291_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 599.0
WLSH3_k127_5639291_4 Winged helix-turn-helix transcription repressor, HrcA DNA-binding K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 578.0
WLSH3_k127_5639291_5 Protein of unknown function (DUF560) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 462.0
WLSH3_k127_5639291_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 454.0
WLSH3_k127_5639291_7 PFAM FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 435.0
WLSH3_k127_5639291_8 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 425.0
WLSH3_k127_5639291_9 glycosyl - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 422.0
WLSH3_k127_5664607_0 type II secretion system protein E K02454,K02652,K12276 - - 6.938e-223 700.0
WLSH3_k127_5664607_1 general secretion pathway protein D K02453 - - 9.11e-215 688.0
WLSH3_k127_5664607_10 general secretion pathway protein K02246,K02247,K02456,K02457,K02458,K10924,K12285 - - 0.000000000000000000000001303 110.0
WLSH3_k127_5664607_11 Type II secretion system protein C K02452 - - 0.000000000001683 76.0
WLSH3_k127_5664607_2 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 460.0
WLSH3_k127_5664607_3 general secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 313.0
WLSH3_k127_5664607_4 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008898 287.0
WLSH3_k127_5664607_5 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000005567 228.0
WLSH3_k127_5664607_6 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000000000000000000000000000000000000000000000002337 181.0
WLSH3_k127_5664607_7 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000002156 141.0
WLSH3_k127_5664607_8 General secretion pathway K02462 - - 0.000000000000000000000000000000006453 134.0
WLSH3_k127_5664607_9 general secretion pathway protein K02463 - - 0.00000000000000000000000002309 118.0
WLSH3_k127_5669640_0 Hsp90 protein K04079 - - 0.0 1052.0
WLSH3_k127_5669640_1 PFAM tRNA synthetase class II (D K and N) K04567 - 6.1.1.6 2.858e-277 858.0
WLSH3_k127_5669640_10 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 322.0
WLSH3_k127_5669640_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000002932 169.0
WLSH3_k127_5669640_12 - - - - 0.000000000000000000000000000000000000000000575 166.0
WLSH3_k127_5669640_13 - - - - 0.0000000000000000000000000000000000000004017 153.0
WLSH3_k127_5669640_14 diguanylate cyclase - - - 0.0000000000000000000000000000000000002571 155.0
WLSH3_k127_5669640_15 PIN domain - - - 0.000000000000000000000000000000001193 134.0
WLSH3_k127_5669640_16 TIGRFAM looped-hinge helix DNA binding domain, AbrB family - - - 0.0000000007582 64.0
WLSH3_k127_5669640_17 membrane - - - 0.000004367 48.0
WLSH3_k127_5669640_18 - - - - 0.0002347 52.0
WLSH3_k127_5669640_2 aminoacyl-histidine dipeptidase K01270 - - 5.301e-230 720.0
WLSH3_k127_5669640_3 Major Facilitator Superfamily - - - 3.472e-217 679.0
WLSH3_k127_5669640_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 572.0
WLSH3_k127_5669640_5 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 483.0
WLSH3_k127_5669640_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 468.0
WLSH3_k127_5669640_7 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 439.0
WLSH3_k127_5669640_8 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 399.0
WLSH3_k127_5669640_9 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 346.0
WLSH3_k127_5687652_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K00533,K18006 - 1.12.1.2,1.12.7.2 0.0 1148.0
WLSH3_k127_5687652_1 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0 1123.0
WLSH3_k127_5687652_2 protein related to capsule biosynthesis enzymes K07154 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 531.0
WLSH3_k127_5687652_3 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003059 279.0
WLSH3_k127_5739280_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 484.0
WLSH3_k127_5739280_1 Flagellar protein YcgR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001789 273.0
WLSH3_k127_5823106_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 3.765e-270 847.0
WLSH3_k127_5823106_1 Diguanylate cyclase - - - 7.958e-243 772.0
WLSH3_k127_5823106_10 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 331.0
WLSH3_k127_5823106_11 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 311.0
WLSH3_k127_5823106_12 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 314.0
WLSH3_k127_5823106_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003074 300.0
WLSH3_k127_5823106_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003315 268.0
WLSH3_k127_5823106_15 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001218 268.0
WLSH3_k127_5823106_16 cell adhesion K02650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001729 265.0
WLSH3_k127_5823106_17 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000003357 252.0
WLSH3_k127_5823106_18 - K09004 - - 0.000000000000000000000000000000000000000000000000001241 186.0
WLSH3_k127_5823106_19 - K09004 - - 0.000000000000000000000000000000000000000000000000004382 185.0
WLSH3_k127_5823106_2 GGDEF domain - - - 3.659e-202 666.0
WLSH3_k127_5823106_20 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000006277 177.0
WLSH3_k127_5823106_21 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000000000000001678 171.0
WLSH3_k127_5823106_22 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.0000000000000000000000000000000000000000000002004 171.0
WLSH3_k127_5823106_23 MarR family - - - 0.0000000000000000000000000000000000000001475 154.0
WLSH3_k127_5823106_24 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.000000000000000000000000000000000000002692 151.0
WLSH3_k127_5823106_25 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000000000005071 118.0
WLSH3_k127_5823106_26 Peptidase family M48 - - - 0.00000000000000004417 84.0
WLSH3_k127_5823106_27 Domain of unknown function (DUF3330) - - - 0.00000000000003038 74.0
WLSH3_k127_5823106_29 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00002314 47.0
WLSH3_k127_5823106_3 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 511.0
WLSH3_k127_5823106_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 474.0
WLSH3_k127_5823106_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 469.0
WLSH3_k127_5823106_6 cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 454.0
WLSH3_k127_5823106_7 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 380.0
WLSH3_k127_5823106_8 SMART metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005604 371.0
WLSH3_k127_5823106_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009254 359.0
WLSH3_k127_6001871_0 'signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 531.0
WLSH3_k127_6001871_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000001378 151.0
WLSH3_k127_6115266_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1321.0
WLSH3_k127_6115266_1 MgsA AAA+ ATPase C terminal K07478 - - 8.258e-243 754.0
WLSH3_k127_6115266_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.033e-209 656.0
WLSH3_k127_6115266_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 483.0
WLSH3_k127_6115266_4 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 483.0
WLSH3_k127_6115266_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 469.0
WLSH3_k127_6115266_6 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 374.0
WLSH3_k127_6115266_7 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 367.0
WLSH3_k127_6115266_8 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 288.0
WLSH3_k127_6115266_9 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000136 59.0
WLSH3_k127_6125724_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1008.0
WLSH3_k127_6125724_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 1.11e-256 794.0
WLSH3_k127_6125724_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 466.0
WLSH3_k127_6125724_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 422.0
WLSH3_k127_6125724_12 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 370.0
WLSH3_k127_6125724_13 6-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 342.0
WLSH3_k127_6125724_14 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
WLSH3_k127_6125724_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 317.0
WLSH3_k127_6125724_16 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 292.0
WLSH3_k127_6125724_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
WLSH3_k127_6125724_18 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007974 278.0
WLSH3_k127_6125724_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.488e-242 753.0
WLSH3_k127_6125724_20 general secretion pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003832 238.0
WLSH3_k127_6125724_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000005529 233.0
WLSH3_k127_6125724_22 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000000000000000000000000000000000000000000000006603 238.0
WLSH3_k127_6125724_23 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
WLSH3_k127_6125724_24 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000022 216.0
WLSH3_k127_6125724_25 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000006532 210.0
WLSH3_k127_6125724_26 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000006442 205.0
WLSH3_k127_6125724_27 - - - - 0.00000000000000000000000000000000000000000000000000001373 195.0
WLSH3_k127_6125724_28 - - - - 0.00000000000000000000000000000000000000000000000001525 196.0
WLSH3_k127_6125724_29 membrane - - - 0.00000000000000000000000000000000000000000000008354 170.0
WLSH3_k127_6125724_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.117e-240 749.0
WLSH3_k127_6125724_30 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000001806 156.0
WLSH3_k127_6125724_31 - - - - 0.00000000000000000000000000000000000000002586 163.0
WLSH3_k127_6125724_32 - - - - 0.00000000000000000000000003328 114.0
WLSH3_k127_6125724_33 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000001389 76.0
WLSH3_k127_6125724_4 PFAM Type II secretion system F domain K02653 - - 1.347e-202 636.0
WLSH3_k127_6125724_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 624.0
WLSH3_k127_6125724_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 563.0
WLSH3_k127_6125724_7 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 561.0
WLSH3_k127_6125724_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 523.0
WLSH3_k127_6125724_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 526.0
WLSH3_k127_6135848_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 402.0
WLSH3_k127_6135848_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000004798 141.0
WLSH3_k127_6135848_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000002264 88.0
WLSH3_k127_6226168_0 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 584.0
WLSH3_k127_6226168_1 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 539.0
WLSH3_k127_6226168_10 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 302.0
WLSH3_k127_6226168_11 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000519 261.0
WLSH3_k127_6226168_12 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000008326 222.0
WLSH3_k127_6226168_13 PFAM FMN-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000001501 203.0
WLSH3_k127_6226168_14 SpoIIAA-like - - - 0.0000000000000000000000000000000000000000000000000006657 185.0
WLSH3_k127_6226168_15 - - - - 0.000000000000000000000000000000000000000000000005932 176.0
WLSH3_k127_6226168_16 Protein of unknown function (DUF493) K09158 - - 0.000000000000000000000002184 107.0
WLSH3_k127_6226168_17 Hemin uptake protein - - - 0.000001696 52.0
WLSH3_k127_6226168_2 SMART Diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 550.0
WLSH3_k127_6226168_3 PFAM aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 440.0
WLSH3_k127_6226168_4 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 424.0
WLSH3_k127_6226168_5 PFAM peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 431.0
WLSH3_k127_6226168_6 EamA-like transporter family K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 376.0
WLSH3_k127_6226168_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 376.0
WLSH3_k127_6226168_8 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 350.0
WLSH3_k127_6226168_9 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 341.0
WLSH3_k127_6260449_0 PFAM nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 289.0
WLSH3_k127_6260449_1 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000002829 168.0
WLSH3_k127_6260449_2 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000004677 166.0
WLSH3_k127_6260449_3 Domain of unknown function (DUF1853) K09977 - - 0.000000000003115 70.0
WLSH3_k127_6322237_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0 1891.0
WLSH3_k127_6322237_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1476.0
WLSH3_k127_6322237_10 SMART PDZ DHR GLGF domain protein K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 612.0
WLSH3_k127_6322237_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 595.0
WLSH3_k127_6322237_12 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 589.0
WLSH3_k127_6322237_13 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 501.0
WLSH3_k127_6322237_14 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 467.0
WLSH3_k127_6322237_15 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 459.0
WLSH3_k127_6322237_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 449.0
WLSH3_k127_6322237_17 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 428.0
WLSH3_k127_6322237_18 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 407.0
WLSH3_k127_6322237_19 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 398.0
WLSH3_k127_6322237_2 Protein of unknown function - - - 0.0 1227.0
WLSH3_k127_6322237_20 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 396.0
WLSH3_k127_6322237_21 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 390.0
WLSH3_k127_6322237_22 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 358.0
WLSH3_k127_6322237_23 Ornithine-acyl acyl carrier protein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 345.0
WLSH3_k127_6322237_24 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 338.0
WLSH3_k127_6322237_25 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 299.0
WLSH3_k127_6322237_26 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 301.0
WLSH3_k127_6322237_27 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 288.0
WLSH3_k127_6322237_28 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003241 278.0
WLSH3_k127_6322237_29 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001894 274.0
WLSH3_k127_6322237_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1206.0
WLSH3_k127_6322237_30 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 267.0
WLSH3_k127_6322237_31 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007756 262.0
WLSH3_k127_6322237_32 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000002736 243.0
WLSH3_k127_6322237_33 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000001535 213.0
WLSH3_k127_6322237_34 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000001046 220.0
WLSH3_k127_6322237_35 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000000005907 205.0
WLSH3_k127_6322237_36 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.00000000000000000000000000000000000000000000000000000001576 201.0
WLSH3_k127_6322237_37 - - - - 0.00000000000000000000000000000000000000000000004104 169.0
WLSH3_k127_6322237_38 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000000000000005063 169.0
WLSH3_k127_6322237_39 CRS1_YhbY K07574 - - 0.0000000000000000000000000000000000000000002818 160.0
WLSH3_k127_6322237_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1022.0
WLSH3_k127_6322237_40 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000003966 128.0
WLSH3_k127_6322237_41 Tfp pilus assembly protein K02655 - - 0.00000000000000000000000000001081 124.0
WLSH3_k127_6322237_42 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000002559 87.0
WLSH3_k127_6322237_43 - - - - 0.00000000000000003176 85.0
WLSH3_k127_6322237_44 - - - - 0.00000004586 59.0
WLSH3_k127_6322237_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1016.0
WLSH3_k127_6322237_6 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 2.179e-225 705.0
WLSH3_k127_6322237_7 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 2.326e-213 672.0
WLSH3_k127_6322237_8 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 1.229e-202 636.0
WLSH3_k127_6322237_9 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 3.748e-196 616.0
WLSH3_k127_6328828_0 PFAM NnrS family protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 317.0
WLSH3_k127_6329121_0 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 9.393e-302 932.0
WLSH3_k127_6329121_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.345e-272 842.0
WLSH3_k127_6329121_10 - - - - 0.000000000000000000000000000000000000000000000000000000001219 224.0
WLSH3_k127_6329121_11 LVIVD repeat - - - 0.000000000000000000000000000000000001045 149.0
WLSH3_k127_6329121_12 Sporulation related domain - - - 0.000000000000000000000000000000000007169 143.0
WLSH3_k127_6329121_13 - - - - 0.000000000000000000000001739 106.0
WLSH3_k127_6329121_14 PFAM Fibronectin, type III domain - - - 0.0000000009569 71.0
WLSH3_k127_6329121_2 Soluble lytic murein transglycosylase L domain K08309 - - 1.228e-252 794.0
WLSH3_k127_6329121_3 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 3.493e-208 652.0
WLSH3_k127_6329121_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 565.0
WLSH3_k127_6329121_5 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 484.0
WLSH3_k127_6329121_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 372.0
WLSH3_k127_6329121_7 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 316.0
WLSH3_k127_6329121_8 DSBA-like thioredoxin domain K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001922 250.0
WLSH3_k127_6329121_9 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000001843 244.0
WLSH3_k127_6383839_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1219.0
WLSH3_k127_6383839_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 570.0
WLSH3_k127_6383839_2 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 512.0
WLSH3_k127_6383839_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 435.0
WLSH3_k127_6383839_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 314.0
WLSH3_k127_6383839_5 Thioredoxin-like K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000001892 234.0
WLSH3_k127_6383839_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000001519 232.0
WLSH3_k127_6383839_7 Domain of unknown function (DUF1956) - - - 0.000000000000000000000000000000000000000000000000000000000003715 214.0
WLSH3_k127_6383839_8 - - - - 0.00000000000000000000000000000000000000000000000000000000008741 214.0
WLSH3_k127_6497836_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.119e-282 891.0
WLSH3_k127_6497836_1 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000007437 239.0
WLSH3_k127_6524535_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 491.0
WLSH3_k127_6524535_1 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 297.0
WLSH3_k127_6678908_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 2139.0
WLSH3_k127_6678908_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1152.0
WLSH3_k127_6678908_10 PFAM sodium calcium exchanger membrane region K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 571.0
WLSH3_k127_6678908_11 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 558.0
WLSH3_k127_6678908_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 526.0
WLSH3_k127_6678908_13 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 519.0
WLSH3_k127_6678908_14 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 508.0
WLSH3_k127_6678908_15 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 507.0
WLSH3_k127_6678908_16 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 496.0
WLSH3_k127_6678908_17 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 491.0
WLSH3_k127_6678908_18 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 448.0
WLSH3_k127_6678908_19 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 445.0
WLSH3_k127_6678908_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 8.849e-270 839.0
WLSH3_k127_6678908_20 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 430.0
WLSH3_k127_6678908_21 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 396.0
WLSH3_k127_6678908_22 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 375.0
WLSH3_k127_6678908_23 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 324.0
WLSH3_k127_6678908_24 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 321.0
WLSH3_k127_6678908_25 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 317.0
WLSH3_k127_6678908_26 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 310.0
WLSH3_k127_6678908_27 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001059 282.0
WLSH3_k127_6678908_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002061 275.0
WLSH3_k127_6678908_29 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 273.0
WLSH3_k127_6678908_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 2.85e-256 811.0
WLSH3_k127_6678908_30 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001236 263.0
WLSH3_k127_6678908_31 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002314 243.0
WLSH3_k127_6678908_32 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001285 243.0
WLSH3_k127_6678908_33 Glyoxalase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000005219 230.0
WLSH3_k127_6678908_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000006702 231.0
WLSH3_k127_6678908_35 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000004242 227.0
WLSH3_k127_6678908_36 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008645 230.0
WLSH3_k127_6678908_37 Putative member of DMT superfamily (DUF486) K09922 - - 0.00000000000000000000000000000000000000000000000000000000003035 207.0
WLSH3_k127_6678908_38 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000001794 198.0
WLSH3_k127_6678908_39 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000005499 186.0
WLSH3_k127_6678908_4 PFAM type II and III secretion system protein K02666 - - 1.575e-247 782.0
WLSH3_k127_6678908_40 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000001488 186.0
WLSH3_k127_6678908_41 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000000000000001119 178.0
WLSH3_k127_6678908_42 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000001211 178.0
WLSH3_k127_6678908_43 Protein of unknown function (DUF805) - - - 0.0000000000000000000000000000000000000000007412 158.0
WLSH3_k127_6678908_44 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000002492 144.0
WLSH3_k127_6678908_45 - - - - 0.00000000000000000000000000000000008887 140.0
WLSH3_k127_6678908_46 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000005492 119.0
WLSH3_k127_6678908_47 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000002317 107.0
WLSH3_k127_6678908_5 Aminotransferase class-III K01845 - 5.4.3.8 1.55e-238 741.0
WLSH3_k127_6678908_6 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 7.24e-238 741.0
WLSH3_k127_6678908_7 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 7.175e-205 647.0
WLSH3_k127_6678908_8 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 606.0
WLSH3_k127_6678908_9 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 571.0
WLSH3_k127_6727332_0 TIGRFAM DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.821e-257 807.0
WLSH3_k127_6727332_1 ATPases involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004888 246.0
WLSH3_k127_6727332_2 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000005853 155.0
WLSH3_k127_6846894_0 Luciferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 514.0
WLSH3_k127_6846894_1 CcdB protein K19163 - - 0.0000000000000000000000000000000000000226 146.0
WLSH3_k127_6846894_2 - - - - 0.000000004514 57.0
WLSH3_k127_6846894_3 Post-segregation antitoxin CcdA K19164 - - 0.0009222 42.0
WLSH3_k127_6874667_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 399.0
WLSH3_k127_6874667_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000004254 143.0
WLSH3_k127_6874667_2 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000000000006042 115.0
WLSH3_k127_6894739_0 KilA-N - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 452.0
WLSH3_k127_6894739_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 283.0
WLSH3_k127_6894739_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000004786 165.0
WLSH3_k127_6901036_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2695.0
WLSH3_k127_6901036_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1105.0
WLSH3_k127_6901036_10 PFAM Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 3.531e-214 671.0
WLSH3_k127_6901036_11 Cytochrome b(N-terminal)/b6/petB K00412 - - 6.872e-213 667.0
WLSH3_k127_6901036_12 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 7.263e-213 663.0
WLSH3_k127_6901036_13 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 1.12e-209 660.0
WLSH3_k127_6901036_14 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 2.367e-207 653.0
WLSH3_k127_6901036_15 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 1.086e-194 608.0
WLSH3_k127_6901036_16 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 591.0
WLSH3_k127_6901036_17 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 561.0
WLSH3_k127_6901036_18 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 556.0
WLSH3_k127_6901036_19 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 552.0
WLSH3_k127_6901036_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.6e-322 1001.0
WLSH3_k127_6901036_20 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 439.0
WLSH3_k127_6901036_21 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 418.0
WLSH3_k127_6901036_22 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 392.0
WLSH3_k127_6901036_23 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 386.0
WLSH3_k127_6901036_24 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 384.0
WLSH3_k127_6901036_25 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 376.0
WLSH3_k127_6901036_26 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 366.0
WLSH3_k127_6901036_27 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 357.0
WLSH3_k127_6901036_28 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 336.0
WLSH3_k127_6901036_29 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 331.0
WLSH3_k127_6901036_3 NADPH-dependent glutamate synthase beta - - - 1.81e-306 949.0
WLSH3_k127_6901036_30 molybdenum cofactor K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 292.0
WLSH3_k127_6901036_31 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000004206 246.0
WLSH3_k127_6901036_32 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000009222 235.0
WLSH3_k127_6901036_33 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000001273 233.0
WLSH3_k127_6901036_34 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
WLSH3_k127_6901036_35 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000001296 221.0
WLSH3_k127_6901036_36 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000001392 207.0
WLSH3_k127_6901036_37 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.0000000000000000000000000000000000000000000000000000002606 200.0
WLSH3_k127_6901036_38 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000002337 189.0
WLSH3_k127_6901036_39 molybdopterin synthase activity K03635 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.00000000000000000000000000000000000000000000000005226 183.0
WLSH3_k127_6901036_4 Cysteine-rich domain - - - 9.864e-285 879.0
WLSH3_k127_6901036_40 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000000000000001735 166.0
WLSH3_k127_6901036_41 Bacterial regulatory protein, Fis family K03557 - - 0.00000000000000000000000000000000000042 141.0
WLSH3_k127_6901036_42 SMART Cold shock protein K03704 - - 0.000000000000000000000000000000000002706 137.0
WLSH3_k127_6901036_43 - - - - 0.00000000000000000000000000000000004059 137.0
WLSH3_k127_6901036_44 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000001498 141.0
WLSH3_k127_6901036_45 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000205 84.0
WLSH3_k127_6901036_46 - - - - 0.00000000000000003095 84.0
WLSH3_k127_6901036_47 chemotaxis, protein K03406 - - 0.0000608 53.0
WLSH3_k127_6901036_5 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.955e-278 861.0
WLSH3_k127_6901036_6 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 2.901e-270 836.0
WLSH3_k127_6901036_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 6.167e-240 748.0
WLSH3_k127_6901036_8 Mo-co oxidoreductase dimerisation domain K17225 - - 1.571e-238 743.0
WLSH3_k127_6901036_9 AAA domain K02224 - 6.3.5.11,6.3.5.9 1.012e-221 695.0
WLSH3_k127_6905725_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.232e-289 899.0
WLSH3_k127_6905725_1 Putative diguanylate phosphodiesterase - - - 1.479e-285 889.0
WLSH3_k127_6905725_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 367.0
WLSH3_k127_6905725_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 321.0
WLSH3_k127_6905725_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 304.0
WLSH3_k127_6905725_13 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000002431 174.0
WLSH3_k127_6905725_14 - - - - 0.00000000000000000000000000000000000000000007008 166.0
WLSH3_k127_6905725_15 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000002493 155.0
WLSH3_k127_6905725_2 phosphate transport system permease K02038 - - 1.332e-250 784.0
WLSH3_k127_6905725_3 PFAM Binding-protein-dependent transport systems inner membrane component K02037 - - 3.307e-241 767.0
WLSH3_k127_6905725_4 Aminotransferase class-III K01845 - 5.4.3.8 2.041e-239 751.0
WLSH3_k127_6905725_5 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 504.0
WLSH3_k127_6905725_6 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 428.0
WLSH3_k127_6905725_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 416.0
WLSH3_k127_6905725_8 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 404.0
WLSH3_k127_6905725_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 391.0
WLSH3_k127_6990370_0 ABC transporter transmembrane region K06147 - - 1.291e-297 921.0
WLSH3_k127_6990370_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 405.0
WLSH3_k127_6990370_10 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.00000000000002057 73.0
WLSH3_k127_6990370_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 384.0
WLSH3_k127_6990370_3 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 285.0
WLSH3_k127_6990370_4 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006399 257.0
WLSH3_k127_6990370_5 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000002527 179.0
WLSH3_k127_6990370_6 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000001128 158.0
WLSH3_k127_6990370_7 YCII-related domain - - - 0.0000000000000000000000000000001195 126.0
WLSH3_k127_6990370_8 Integrase core domain K07482 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004803,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006310,GO:0006313,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0030983,GO:0032135,GO:0032196,GO:0032991,GO:0032993,GO:0034641,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000003363 98.0
WLSH3_k127_6992739_0 PFAM TrkA-N domain protein K03499 - - 2.131e-237 739.0
WLSH3_k127_6992739_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 6.199e-232 726.0
WLSH3_k127_6992739_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.313e-212 665.0
WLSH3_k127_6992739_3 Inositol monophosphatase family K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 387.0
WLSH3_k127_6992739_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 327.0
WLSH3_k127_6992739_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008748 322.0
WLSH3_k127_7099395_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1505.0
WLSH3_k127_7099395_1 AAA ATPase domain - - - 1.202e-310 982.0
WLSH3_k127_7099395_10 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 365.0
WLSH3_k127_7099395_11 protein-glutamate methylesterase activity K03412,K03413,K13924 - 2.1.1.80,3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 313.0
WLSH3_k127_7099395_12 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 307.0
WLSH3_k127_7099395_13 HTH-like domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 306.0
WLSH3_k127_7099395_14 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000737 253.0
WLSH3_k127_7099395_15 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000007405 194.0
WLSH3_k127_7099395_16 - - - - 0.000000000000000000000000000000000000000000000000000008685 193.0
WLSH3_k127_7099395_17 - - - - 0.0000000000000000000000000000000006925 134.0
WLSH3_k127_7099395_18 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000003062 124.0
WLSH3_k127_7099395_19 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000002834 119.0
WLSH3_k127_7099395_2 Belongs to the glutamate synthase family - - - 9.329e-237 740.0
WLSH3_k127_7099395_20 Helix-turn-helix domain K07483 - - 0.0000000000000000000000000008672 114.0
WLSH3_k127_7099395_21 - - - - 0.00000000000000000000000002172 111.0
WLSH3_k127_7099395_22 Predicted membrane protein (DUF2306) - - - 0.000000000000000000001665 98.0
WLSH3_k127_7099395_23 - - - - 0.0000000000000000008201 88.0
WLSH3_k127_7099395_24 Tfp pilus assembly protein FimV - - - 0.00000000000000246 81.0
WLSH3_k127_7099395_25 HTH-like domain K07497 - - 0.00000000000001207 74.0
WLSH3_k127_7099395_26 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000007315 63.0
WLSH3_k127_7099395_27 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00001661 47.0
WLSH3_k127_7099395_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 1.33e-228 717.0
WLSH3_k127_7099395_4 HELICc2 K03722 - 3.6.4.12 1.083e-199 629.0
WLSH3_k127_7099395_5 'signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 581.0
WLSH3_k127_7099395_6 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 462.0
WLSH3_k127_7099395_7 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 407.0
WLSH3_k127_7099395_8 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 404.0
WLSH3_k127_7099395_9 Domain of unknown function (DUF1794) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 372.0
WLSH3_k127_7165074_0 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 0.0 1312.0
WLSH3_k127_7165074_1 DHH family K07462 - - 6.322e-277 861.0
WLSH3_k127_7165074_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 509.0
WLSH3_k127_7165074_3 Histidine kinase K07675,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 454.0
WLSH3_k127_7165074_4 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003942 266.0
WLSH3_k127_7165074_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000001077 223.0
WLSH3_k127_7165074_6 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000000000000000004752 176.0
WLSH3_k127_7165074_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000003119 155.0
WLSH3_k127_7165074_9 - - - - 0.00000000000000718 76.0
WLSH3_k127_7194645_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1245.0
WLSH3_k127_7194645_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.24e-260 807.0
WLSH3_k127_7194645_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 346.0
WLSH3_k127_7194645_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 317.0
WLSH3_k127_7194645_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
WLSH3_k127_7194645_13 PFAM lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 307.0
WLSH3_k127_7194645_14 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 290.0
WLSH3_k127_7194645_16 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007849 268.0
WLSH3_k127_7194645_17 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000001009 270.0
WLSH3_k127_7194645_18 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001928 265.0
WLSH3_k127_7194645_19 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000002427 214.0
WLSH3_k127_7194645_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 2.464e-229 717.0
WLSH3_k127_7194645_20 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000000000000001233 202.0
WLSH3_k127_7194645_21 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000000000389 197.0
WLSH3_k127_7194645_22 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000000001964 192.0
WLSH3_k127_7194645_23 PFAM DNA-repair protein, UmuC-like K03502 - - 0.00000000000000000000000000000000000000000000006094 173.0
WLSH3_k127_7194645_24 Dual specificity phosphatase, catalytic domain - - - 0.0000000000000000000000000000000000000000002061 168.0
WLSH3_k127_7194645_25 positive regulation of growth - - - 0.000000000000000000000002993 104.0
WLSH3_k127_7194645_26 Protein of unknown function (DUF2798) - - - 0.000000000000000000000004156 103.0
WLSH3_k127_7194645_27 Nacht domain - - - 0.0000000000504 63.0
WLSH3_k127_7194645_28 Domain of unknown function (DUF4389) - - - 0.0000002924 53.0
WLSH3_k127_7194645_29 - - - - 0.0001416 53.0
WLSH3_k127_7194645_3 Starch synthase catalytic domain K00703 - 2.4.1.21 1.427e-200 634.0
WLSH3_k127_7194645_4 Belongs to the heat shock protein 70 family K04046 - - 4.171e-200 631.0
WLSH3_k127_7194645_5 leucine-rich repeat-containing protein typical subtype - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 563.0
WLSH3_k127_7194645_6 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 499.0
WLSH3_k127_7194645_7 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 441.0
WLSH3_k127_7194645_8 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 355.0
WLSH3_k127_7194645_9 PFAM DNA-repair protein, UmuC-like K03502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 347.0
WLSH3_k127_7196158_0 PhoQ Sensor - - - 9.559e-202 642.0
WLSH3_k127_7196158_1 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 566.0
WLSH3_k127_7196158_3 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 292.0
WLSH3_k127_7196158_4 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000004375 238.0
WLSH3_k127_7196158_5 Rhodanese domain protein - - - 0.000000000000000000000000000000000000004415 148.0
WLSH3_k127_7205629_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 5.423e-213 669.0
WLSH3_k127_7205629_1 restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 481.0
WLSH3_k127_7205629_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 400.0
WLSH3_k127_7205629_3 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 324.0
WLSH3_k127_7205629_4 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000004132 237.0
WLSH3_k127_7205629_5 PFAM NnrS family protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000001949 216.0
WLSH3_k127_7205629_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000003225 174.0
WLSH3_k127_7205629_7 PFAM PsiF repeat protein - - - 0.00000000000000000000007424 100.0
WLSH3_k127_7234249_0 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 445.0
WLSH3_k127_7234249_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 381.0
WLSH3_k127_7234249_10 - - - - 0.0000000000000000005084 91.0
WLSH3_k127_7234249_11 positive regulation of growth - - - 0.00000000005973 70.0
WLSH3_k127_7234249_2 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001795 276.0
WLSH3_k127_7234249_3 RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000003656 211.0
WLSH3_k127_7234249_5 LVIVD repeat - - - 0.000000000000000000000000000000000000000000000000001558 193.0
WLSH3_k127_7234249_6 TQO small subunit DoxD K15977 - - 0.00000000000000000000000000000000000000000000956 167.0
WLSH3_k127_7234249_7 PIN domain - - - 0.0000000000000000000000000000000000000000003586 161.0
WLSH3_k127_7234249_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000002291 154.0
WLSH3_k127_7234249_9 CAAX protease self-immunity K07052 - - 0.0000000000000000000000009832 110.0
WLSH3_k127_7261444_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 455.0
WLSH3_k127_7261444_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 322.0
WLSH3_k127_7261444_2 PFAM Integrase, catalytic core K07497 - - 0.0000598 46.0
WLSH3_k127_7343978_0 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 439.0
WLSH3_k127_7343978_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 414.0
WLSH3_k127_7343978_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 367.0
WLSH3_k127_7343978_3 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 336.0
WLSH3_k127_7343978_4 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001892 254.0
WLSH3_k127_7343978_5 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000000008729 200.0
WLSH3_k127_7343978_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000004166 104.0
WLSH3_k127_7343978_7 - - - - 0.0000000000000000005292 93.0
WLSH3_k127_7343978_8 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000003832 87.0
WLSH3_k127_7343978_9 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000008188 78.0
WLSH3_k127_7370058_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1338.0
WLSH3_k127_7370058_1 Sulfate permease family K03321 - - 2.743e-278 860.0
WLSH3_k127_7370058_10 Phage derived protein Gp49-like (DUF891) - - - 0.000000000003364 66.0
WLSH3_k127_7370058_2 Chloride channel - - - 1.703e-213 669.0
WLSH3_k127_7370058_3 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 605.0
WLSH3_k127_7370058_4 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000003581 232.0
WLSH3_k127_7370058_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002386 225.0
WLSH3_k127_7370058_6 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000006516 217.0
WLSH3_k127_7370058_7 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001677 216.0
WLSH3_k127_7370058_8 Helix-turn-helix motif - - - 0.000000000000000000000000000004248 122.0
WLSH3_k127_7370058_9 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000003474 92.0
WLSH3_k127_7398362_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1570.0
WLSH3_k127_7398362_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1538.0
WLSH3_k127_7398362_10 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 3.041e-217 676.0
WLSH3_k127_7398362_11 DNA photolyase K01669 - 4.1.99.3 1.361e-215 677.0
WLSH3_k127_7398362_12 PFAM type II secretion system protein E K02670 - - 9.058e-205 641.0
WLSH3_k127_7398362_13 PFAM type II secretion system protein E K02669,K12203 - - 8.677e-203 633.0
WLSH3_k127_7398362_14 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 576.0
WLSH3_k127_7398362_15 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 571.0
WLSH3_k127_7398362_16 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
WLSH3_k127_7398362_17 THUMP K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 525.0
WLSH3_k127_7398362_18 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 526.0
WLSH3_k127_7398362_19 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007852 484.0
WLSH3_k127_7398362_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1401.0
WLSH3_k127_7398362_20 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 506.0
WLSH3_k127_7398362_21 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 473.0
WLSH3_k127_7398362_22 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 457.0
WLSH3_k127_7398362_23 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 466.0
WLSH3_k127_7398362_24 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 418.0
WLSH3_k127_7398362_25 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 400.0
WLSH3_k127_7398362_26 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 392.0
WLSH3_k127_7398362_27 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 389.0
WLSH3_k127_7398362_28 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 387.0
WLSH3_k127_7398362_29 Inner membrane protein CreD K06143 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 381.0
WLSH3_k127_7398362_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1364.0
WLSH3_k127_7398362_30 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 363.0
WLSH3_k127_7398362_31 VanZ like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 332.0
WLSH3_k127_7398362_32 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 323.0
WLSH3_k127_7398362_33 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 321.0
WLSH3_k127_7398362_34 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 327.0
WLSH3_k127_7398362_35 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 298.0
WLSH3_k127_7398362_36 Transcriptional regulatory protein, C terminal K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 287.0
WLSH3_k127_7398362_37 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 288.0
WLSH3_k127_7398362_38 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001434 280.0
WLSH3_k127_7398362_39 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009217 265.0
WLSH3_k127_7398362_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 3.8e-279 863.0
WLSH3_k127_7398362_40 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000007336 257.0
WLSH3_k127_7398362_41 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000003617 246.0
WLSH3_k127_7398362_42 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002354 247.0
WLSH3_k127_7398362_43 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000007377 231.0
WLSH3_k127_7398362_44 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000001232 222.0
WLSH3_k127_7398362_45 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000003227 223.0
WLSH3_k127_7398362_46 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000004432 221.0
WLSH3_k127_7398362_47 - - - - 0.000000000000000000000000000000000000000000000000000000000000003427 225.0
WLSH3_k127_7398362_48 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000001008 219.0
WLSH3_k127_7398362_49 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000000000000000263 214.0
WLSH3_k127_7398362_5 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 4.479e-266 822.0
WLSH3_k127_7398362_50 DsrE/DsrF-like family K07236 - - 0.00000000000000000000000000000000000000000000000000000000001692 207.0
WLSH3_k127_7398362_51 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000002166 205.0
WLSH3_k127_7398362_52 - - - - 0.000000000000000000000000000000000000000000000000000000001348 207.0
WLSH3_k127_7398362_53 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000003908 199.0
WLSH3_k127_7398362_54 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000007668 196.0
WLSH3_k127_7398362_55 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000000000000003874 199.0
WLSH3_k127_7398362_56 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000001223 186.0
WLSH3_k127_7398362_57 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000001072 181.0
WLSH3_k127_7398362_58 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000000000002632 181.0
WLSH3_k127_7398362_59 Cas6 Crispr - - - 0.00000000000000000000000000000000000000000000004088 177.0
WLSH3_k127_7398362_6 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 3.512e-261 811.0
WLSH3_k127_7398362_60 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000008037 171.0
WLSH3_k127_7398362_61 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000002736 159.0
WLSH3_k127_7398362_62 DsrH like protein K07237 - - 0.0000000000000000000000000000000000000004341 150.0
WLSH3_k127_7398362_63 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000298 152.0
WLSH3_k127_7398362_64 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000003253 149.0
WLSH3_k127_7398362_65 - - - - 0.000000000000000000000000000000000000004844 149.0
WLSH3_k127_7398362_66 toxin-antitoxin pair type II binding K18923,K19161 GO:0006355,GO:0006950,GO:0006974,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0044092,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000001675 145.0
WLSH3_k127_7398362_67 TfoX N-terminal domain K07343 - - 0.00000000000000000000000000000000000005833 145.0
WLSH3_k127_7398362_68 Domain of unknown function (DUF3817) - - - 0.00000000000000000000000000000000000057 141.0
WLSH3_k127_7398362_69 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000006373 142.0
WLSH3_k127_7398362_7 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 1.64e-244 759.0
WLSH3_k127_7398362_70 DUF167 K09131 - - 0.000000000000000000000000000000000004867 139.0
WLSH3_k127_7398362_71 Protein of unknown function (DUF2288) - - - 0.000000000000000000000000000002963 123.0
WLSH3_k127_7398362_72 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000000236 120.0
WLSH3_k127_7398362_73 - - - - 0.00000000000000000000000000005574 124.0
WLSH3_k127_7398362_74 - - - - 0.0000000000000000000000001372 110.0
WLSH3_k127_7398362_75 - - - - 0.00000000000000000000000153 104.0
WLSH3_k127_7398362_78 silverDB K06218 - - 0.0000000000000000282 84.0
WLSH3_k127_7398362_79 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000001861 77.0
WLSH3_k127_7398362_8 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 7.257e-236 746.0
WLSH3_k127_7398362_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 1.133e-232 725.0
WLSH3_k127_7499000_0 AcrB/AcrD/AcrF family - - - 0.0 1400.0
WLSH3_k127_7499000_1 Diguanylate cyclase - - - 0.0 1002.0
WLSH3_k127_7499000_11 LPP20 lipoprotein - - - 0.000000000000000000002517 100.0
WLSH3_k127_7499000_12 Multicopper oxidase - - - 0.000000001158 59.0
WLSH3_k127_7499000_13 Chemoreceptor zinc-binding domain - - - 0.000001851 52.0
WLSH3_k127_7499000_2 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 1.625e-208 655.0
WLSH3_k127_7499000_3 surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 603.0
WLSH3_k127_7499000_4 PFAM aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 479.0
WLSH3_k127_7499000_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 363.0
WLSH3_k127_7499000_6 PFAM multicopper oxidase type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 330.0
WLSH3_k127_7499000_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003153 284.0
WLSH3_k127_7499000_8 Flagellar protein YcgR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004302 256.0
WLSH3_k127_7499000_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000001074 181.0
WLSH3_k127_7619316_0 Sodium:solute symporter family K14393 - - 0.0 1092.0
WLSH3_k127_7619316_1 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 608.0
WLSH3_k127_7619316_10 - - - - 0.0000000000000000000001421 101.0
WLSH3_k127_7619316_2 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 467.0
WLSH3_k127_7619316_3 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 408.0
WLSH3_k127_7619316_4 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 370.0
WLSH3_k127_7619316_5 Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 336.0
WLSH3_k127_7619316_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 322.0
WLSH3_k127_7619316_7 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 300.0
WLSH3_k127_7619316_8 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000003273 161.0
WLSH3_k127_7619316_9 membrane - - - 0.0000000000000000000000000000000000003712 141.0
WLSH3_k127_7629999_0 diguanylate cyclase K13590 - 2.7.7.65 1.99e-218 690.0
WLSH3_k127_7629999_1 Belongs to the peptidase M16 family K07263 - - 1.572e-207 654.0
WLSH3_k127_7629999_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 514.0
WLSH3_k127_7629999_11 TIGRFAM flagellar motor switch protein FliG K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 487.0
WLSH3_k127_7629999_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 457.0
WLSH3_k127_7629999_13 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 449.0
WLSH3_k127_7629999_14 Ribosomal RNA adenine dimethylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 428.0
WLSH3_k127_7629999_15 Sigma-70 factor, region 1.2 K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 406.0
WLSH3_k127_7629999_16 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 394.0
WLSH3_k127_7629999_17 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 385.0
WLSH3_k127_7629999_18 Glutathione S-transferase, C-terminal domain K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 369.0
WLSH3_k127_7629999_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 367.0
WLSH3_k127_7629999_2 The M ring may be actively involved in energy transduction K02409 - - 2.448e-201 640.0
WLSH3_k127_7629999_20 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 349.0
WLSH3_k127_7629999_21 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 349.0
WLSH3_k127_7629999_22 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 347.0
WLSH3_k127_7629999_23 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 336.0
WLSH3_k127_7629999_24 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 326.0
WLSH3_k127_7629999_25 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 316.0
WLSH3_k127_7629999_26 PFAM Ankyrin K10799 - 2.4.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002248 280.0
WLSH3_k127_7629999_27 Scaffold protein Nfu/NifU N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 266.0
WLSH3_k127_7629999_28 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 258.0
WLSH3_k127_7629999_29 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000004029 247.0
WLSH3_k127_7629999_3 PFAM peptidase S1 and S6 chymotrypsin Hap K04691,K04772 - - 2.204e-197 620.0
WLSH3_k127_7629999_30 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000001483 246.0
WLSH3_k127_7629999_31 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000006526 239.0
WLSH3_k127_7629999_32 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000000000000000000000000000000000000000005579 222.0
WLSH3_k127_7629999_33 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000000002225 201.0
WLSH3_k127_7629999_34 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.000000000000000000000000000000000000000000000000000000005408 208.0
WLSH3_k127_7629999_35 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000006967 193.0
WLSH3_k127_7629999_36 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000001647 186.0
WLSH3_k127_7629999_37 HIT domain K02503 - - 0.000000000000000000000000000000000000000000000001635 175.0
WLSH3_k127_7629999_38 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000001568 160.0
WLSH3_k127_7629999_39 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.0000000000000000000000000000000000000000003157 159.0
WLSH3_k127_7629999_4 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 601.0
WLSH3_k127_7629999_40 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000004357 156.0
WLSH3_k127_7629999_41 PFAM Flagellar protein FliS K02422 - - 0.0000000000000000000000000000000000000009418 153.0
WLSH3_k127_7629999_42 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412 - 3.6.3.14 0.000000000000000000000000000000000000004061 149.0
WLSH3_k127_7629999_43 FlhB HrpN YscU SpaS Family K04061 - - 0.0000000000000000000000000000000000002425 142.0
WLSH3_k127_7629999_44 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000005501 143.0
WLSH3_k127_7629999_45 TIGRFAM flagellar hook-basal body complex subunit FliE K02408 - - 0.000000000000000000000000000000000009939 139.0
WLSH3_k127_7629999_46 Flagellar protein FliT K02423 - - 0.0000000000000000000000000001148 117.0
WLSH3_k127_7629999_47 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000001563 109.0
WLSH3_k127_7629999_48 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000553 110.0
WLSH3_k127_7629999_49 MltA-interacting protein MipA K07274 - - 0.0000000001344 72.0
WLSH3_k127_7629999_5 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 577.0
WLSH3_k127_7629999_50 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000001179 53.0
WLSH3_k127_7629999_51 FlaG protein - - - 0.0000006494 56.0
WLSH3_k127_7629999_52 DNA polymerase type-B family K02336 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00001434 48.0
WLSH3_k127_7629999_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 536.0
WLSH3_k127_7629999_7 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 544.0
WLSH3_k127_7629999_8 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 532.0
WLSH3_k127_7629999_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 523.0
WLSH3_k127_7723235_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1460.0
WLSH3_k127_7723235_1 Neisseria PilC beta-propeller domain K02674 - - 2.261e-240 770.0
WLSH3_k127_7723235_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 4.068e-208 649.0
WLSH3_k127_7723235_3 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 7.636e-195 613.0
WLSH3_k127_7723235_4 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 433.0
WLSH3_k127_7723235_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 405.0
WLSH3_k127_7723235_6 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 299.0
WLSH3_k127_7723235_7 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 282.0
WLSH3_k127_7723235_8 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000001026 179.0
WLSH3_k127_7945613_0 Chromate transporter K07240 - - 6.931e-238 741.0
WLSH3_k127_7945613_1 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 315.0
WLSH3_k127_7945613_2 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
WLSH3_k127_7945613_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000004272 228.0
WLSH3_k127_7945613_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000001098 199.0
WLSH3_k127_7945613_5 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000002078 141.0
WLSH3_k127_7945613_6 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000001395 136.0
WLSH3_k127_7945613_7 Rhodanese domain protein - - - 0.00000000000000000000000000001533 123.0
WLSH3_k127_7945613_8 and Ankyrin domain protein - - - 0.0000000000000000000000000001784 132.0
WLSH3_k127_7966203_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 7.398e-199 622.0
WLSH3_k127_7966203_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 9.369e-198 623.0
WLSH3_k127_7966203_2 AAA domain K07028 - - 4.779e-196 625.0
WLSH3_k127_7966203_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 584.0
WLSH3_k127_7966203_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 497.0
WLSH3_k127_7966203_5 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003852 247.0
WLSH3_k127_7966203_6 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000008791 137.0
WLSH3_k127_8002505_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1616.0
WLSH3_k127_8002505_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1116.0
WLSH3_k127_8002505_10 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 506.0
WLSH3_k127_8002505_11 endonuclease III K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 503.0
WLSH3_k127_8002505_12 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 501.0
WLSH3_k127_8002505_13 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 493.0
WLSH3_k127_8002505_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 490.0
WLSH3_k127_8002505_15 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 464.0
WLSH3_k127_8002505_16 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 443.0
WLSH3_k127_8002505_17 P-loop ATPase protein family K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 426.0
WLSH3_k127_8002505_18 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 402.0
WLSH3_k127_8002505_19 Diguanylate cyclase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 395.0
WLSH3_k127_8002505_2 AsmA family K07289 - - 3.695e-255 807.0
WLSH3_k127_8002505_20 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 376.0
WLSH3_k127_8002505_21 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 371.0
WLSH3_k127_8002505_22 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 374.0
WLSH3_k127_8002505_23 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 334.0
WLSH3_k127_8002505_24 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 313.0
WLSH3_k127_8002505_25 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 308.0
WLSH3_k127_8002505_26 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 310.0
WLSH3_k127_8002505_27 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 304.0
WLSH3_k127_8002505_28 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 295.0
WLSH3_k127_8002505_29 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 283.0
WLSH3_k127_8002505_3 2-Nitropropane dioxygenase K00459 - 1.13.12.16 5.268e-229 713.0
WLSH3_k127_8002505_30 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 259.0
WLSH3_k127_8002505_31 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000002018 239.0
WLSH3_k127_8002505_32 SMART Signal transduction response regulator, receiver region - - - 0.00000000000000000000000000000000000000000000000000000000000000163 221.0
WLSH3_k127_8002505_33 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000000000000000000000000001646 203.0
WLSH3_k127_8002505_34 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000001883 182.0
WLSH3_k127_8002505_35 PFAM sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000000001935 177.0
WLSH3_k127_8002505_36 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000002632 187.0
WLSH3_k127_8002505_37 translation initiation factor activity - - - 0.0000000000000000000000000000000002406 136.0
WLSH3_k127_8002505_38 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000001048 121.0
WLSH3_k127_8002505_39 ThiS family K03154 - - 0.00000000000000000001551 92.0
WLSH3_k127_8002505_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 6.052e-222 691.0
WLSH3_k127_8002505_40 - K06950 - - 0.00000000000000008377 83.0
WLSH3_k127_8002505_41 NusG domain II - - - 0.0000000002611 69.0
WLSH3_k127_8002505_5 Diguanylate cyclase - - - 3.989e-217 688.0
WLSH3_k127_8002505_6 PFAM sigma-54 factor interaction domain-containing protein K02667 - - 7.437e-210 664.0
WLSH3_k127_8002505_7 Involved in the biosynthesis of porphyrin-containing compound - - - 1.638e-199 628.0
WLSH3_k127_8002505_8 Anthranilate synthase component I domain protein K01665,K13950 - 2.6.1.85 3.868e-195 618.0
WLSH3_k127_8002505_9 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 608.0
WLSH3_k127_8139948_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.784e-199 624.0
WLSH3_k127_8139948_1 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 460.0
WLSH3_k127_8139948_2 Phosphate ATP-binding cassette transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006709 285.0
WLSH3_k127_8139948_3 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000002892 241.0
WLSH3_k127_8139948_4 - - - - 0.0000007376 54.0
WLSH3_k127_8139948_5 phosphate transport system permease K02038 - - 0.000006696 52.0
WLSH3_k127_8143573_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.61e-291 906.0
WLSH3_k127_8143573_1 PFAM type II and III secretion system protein K02453,K12282 - - 3.937e-205 654.0
WLSH3_k127_8143573_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 333.0
WLSH3_k127_8143573_11 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 299.0
WLSH3_k127_8143573_12 rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006054 273.0
WLSH3_k127_8143573_13 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000007649 244.0
WLSH3_k127_8143573_14 pyrroloquinoline quinone binding K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001772 272.0
WLSH3_k127_8143573_15 carbon utilization K12280 - - 0.000000000000000000000000000000000000000000000000000000000005743 214.0
WLSH3_k127_8143573_16 Fimbrial assembly protein (PilN) - - - 0.0000000000000000000000000000000000000000000000000000000001331 211.0
WLSH3_k127_8143573_17 Tetratricopeptide repeat K12284 - - 0.000000000000000000000000000000000000000000000000000008235 207.0
WLSH3_k127_8143573_18 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000004856 185.0
WLSH3_k127_8143573_19 alginic acid biosynthetic process K12287 - - 0.000000000000000000000000000000000000000629 171.0
WLSH3_k127_8143573_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 8.715e-205 642.0
WLSH3_k127_8143573_20 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000007505 138.0
WLSH3_k127_8143573_21 - K12281 - - 0.0000009684 56.0
WLSH3_k127_8143573_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 548.0
WLSH3_k127_8143573_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 535.0
WLSH3_k127_8143573_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 536.0
WLSH3_k127_8143573_6 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 482.0
WLSH3_k127_8143573_7 AAA domain K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006581 471.0
WLSH3_k127_8143573_8 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 401.0
WLSH3_k127_8143573_9 Pilus assembly protein K12279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 353.0
WLSH3_k127_8165344_0 Belongs to the GPI family K01810 GO:0003674,GO:0003824,GO:0004347,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033554,GO:0034404,GO:0034599,GO:0034641,GO:0034654,GO:0034655,GO:0042221,GO:0042802,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0055086,GO:0070887,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.3.1.9 8.962e-254 792.0
WLSH3_k127_8165344_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 8.969e-199 627.0
WLSH3_k127_8165344_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 476.0
WLSH3_k127_8165344_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 362.0
WLSH3_k127_8165344_4 ATPases associated with a variety of cellular activities K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 319.0
WLSH3_k127_8165344_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000002468 250.0
WLSH3_k127_8165344_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000005742 188.0
WLSH3_k127_8165344_7 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000003322 87.0
WLSH3_k127_8166785_0 Major Facilitator - - - 1.682e-243 753.0
WLSH3_k127_8166785_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 465.0
WLSH3_k127_8166785_2 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 401.0
WLSH3_k127_8166785_3 PFAM Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 342.0
WLSH3_k127_8166785_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000002258 149.0
WLSH3_k127_8166785_5 Major Facilitator - - - 0.0000000000000000006021 89.0
WLSH3_k127_8177570_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1131.0
WLSH3_k127_8177570_1 TIGRFAM cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1096.0
WLSH3_k127_8177570_10 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 357.0
WLSH3_k127_8177570_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 342.0
WLSH3_k127_8177570_12 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 294.0
WLSH3_k127_8177570_13 TIGRFAM periplasmic protein thiol disulphide oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000514 279.0
WLSH3_k127_8177570_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
WLSH3_k127_8177570_15 Bacterial transferase hexapeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000003278 232.0
WLSH3_k127_8177570_16 Cytochrome C biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
WLSH3_k127_8177570_17 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000001632 192.0
WLSH3_k127_8177570_18 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000009907 190.0
WLSH3_k127_8177570_19 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000001198 169.0
WLSH3_k127_8177570_2 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1088.0
WLSH3_k127_8177570_20 PFAM SpoVT AbrB - - - 0.000000000000000000000000000000003882 129.0
WLSH3_k127_8177570_21 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.0000000000001305 71.0
WLSH3_k127_8177570_22 - - - - 0.00000000003442 63.0
WLSH3_k127_8177570_23 - - - - 0.0000000003885 65.0
WLSH3_k127_8177570_3 SurA N-terminal domain K03770 - 5.2.1.8 9.56e-242 763.0
WLSH3_k127_8177570_4 PFAM aminotransferase class I and II K00812 - 2.6.1.1 1.549e-230 716.0
WLSH3_k127_8177570_5 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 595.0
WLSH3_k127_8177570_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 484.0
WLSH3_k127_8177570_7 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 460.0
WLSH3_k127_8177570_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 434.0
WLSH3_k127_8177570_9 translation initiation factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 463.0
WLSH3_k127_8203063_0 Elements of external origin K07494 - - 1.279e-197 620.0
WLSH3_k127_8203063_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006718 415.0
WLSH3_k127_8203063_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000008686 141.0
WLSH3_k127_8336313_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.502e-243 757.0
WLSH3_k127_8336313_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 551.0
WLSH3_k127_8336313_2 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 539.0
WLSH3_k127_8336313_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 425.0
WLSH3_k127_8336313_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 381.0
WLSH3_k127_8336313_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 366.0
WLSH3_k127_8336313_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 305.0
WLSH3_k127_8336313_7 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004977 245.0
WLSH3_k127_8336313_8 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000000001071 194.0
WLSH3_k127_8336313_9 PFAM NHL repeat containing protein - - - 0.0000008881 55.0
WLSH3_k127_8404024_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1076.0
WLSH3_k127_8404024_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 485.0
WLSH3_k127_8404024_2 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 429.0
WLSH3_k127_8404024_3 PFAM Blue (type 1) copper domain - - - 0.000000000000000000000000000000000000000000000000000000001509 205.0
WLSH3_k127_8404024_4 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000004129 185.0
WLSH3_k127_8404024_5 Copper binding periplasmic protein CusF - - - 0.000000000000000000000000000008725 121.0
WLSH3_k127_8415855_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1688.0
WLSH3_k127_8415855_1 PFAM Orn Lys Arg decarboxylase major region K01584 - 4.1.1.19 0.0 1388.0
WLSH3_k127_8415855_10 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 391.0
WLSH3_k127_8415855_11 LytTr DNA-binding domain K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 369.0
WLSH3_k127_8415855_12 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 340.0
WLSH3_k127_8415855_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002601 261.0
WLSH3_k127_8415855_14 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000003956 181.0
WLSH3_k127_8415855_15 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000009522 158.0
WLSH3_k127_8415855_16 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000007282 156.0
WLSH3_k127_8415855_17 Addiction module toxin RelE StbE family - - - 0.0000000000000000000000000000000000003712 141.0
WLSH3_k127_8415855_18 sequence-specific DNA binding - - - 0.000000000000000000000000000000000002062 141.0
WLSH3_k127_8415855_19 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000007493 142.0
WLSH3_k127_8415855_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1087.0
WLSH3_k127_8415855_20 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000001983 119.0
WLSH3_k127_8415855_21 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000002108 113.0
WLSH3_k127_8415855_22 - - - - 0.000000000000000000000005213 107.0
WLSH3_k127_8415855_23 Domain of unknown function (DUF4105) - - - 0.000000000000253 72.0
WLSH3_k127_8415855_25 Restriction endonuclease - - - 0.00005684 46.0
WLSH3_k127_8415855_3 fibronectin type III domain protein K06882 - - 1.799e-311 969.0
WLSH3_k127_8415855_4 Putative diguanylate phosphodiesterase - - - 9.764e-310 975.0
WLSH3_k127_8415855_5 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 6.32e-252 783.0
WLSH3_k127_8415855_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 9.562e-225 701.0
WLSH3_k127_8415855_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 1.213e-196 617.0
WLSH3_k127_8415855_8 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 602.0
WLSH3_k127_8415855_9 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 383.0
WLSH3_k127_843160_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.468e-297 917.0
WLSH3_k127_843160_1 response regulator receiver - - - 1.164e-254 824.0
WLSH3_k127_843160_10 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 287.0
WLSH3_k127_843160_11 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004749 260.0
WLSH3_k127_843160_12 Response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000006504 188.0
WLSH3_k127_843160_13 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000009292 164.0
WLSH3_k127_843160_14 CheW-like domain - - - 0.0000000000000000000000000000000000002379 147.0
WLSH3_k127_843160_15 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000006978 151.0
WLSH3_k127_843160_16 - - - - 0.00000000000000000000000002296 113.0
WLSH3_k127_843160_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 9.935e-248 769.0
WLSH3_k127_843160_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 4.265e-239 745.0
WLSH3_k127_843160_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 9.296e-229 711.0
WLSH3_k127_843160_5 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 526.0
WLSH3_k127_843160_6 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 497.0
WLSH3_k127_843160_7 chemotaxis, protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 430.0
WLSH3_k127_843160_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 351.0
WLSH3_k127_843160_9 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 323.0
WLSH3_k127_8443679_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 563.0
WLSH3_k127_8443679_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 385.0
WLSH3_k127_8443679_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 362.0
WLSH3_k127_8443679_3 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
WLSH3_k127_8443679_4 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000000004114 107.0
WLSH3_k127_8443679_5 DNA polymerase type-B family K02336 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0001207 47.0
WLSH3_k127_8518623_0 Predicted membrane protein (DUF2339) - - - 5.228e-244 783.0
WLSH3_k127_8518623_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 529.0
WLSH3_k127_8518623_10 NMT1-like family - - - 0.00000000000000003784 93.0
WLSH3_k127_8518623_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 438.0
WLSH3_k127_8518623_3 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 370.0
WLSH3_k127_8518623_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 347.0
WLSH3_k127_8518623_5 Protein of unknown function (DUF3999) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 329.0
WLSH3_k127_8518623_6 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 288.0
WLSH3_k127_8518623_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000006577 220.0
WLSH3_k127_8518623_8 phosphinothricin N-acetyltransferase activity K03830 - - 0.00000000000000000000000000000000000000000001744 167.0
WLSH3_k127_852085_0 Enoyl-CoA hydratase/isomerase K07516 - 1.1.1.35 0.0 1350.0
WLSH3_k127_852085_1 AMP-binding enzyme K01897 - 6.2.1.3 2.156e-253 794.0
WLSH3_k127_852085_10 Antitoxin component of a toxin-antitoxin (TA) module K18923 - - 0.00000000000000000000000000000000006037 136.0
WLSH3_k127_852085_2 Thiolase, C-terminal domain K00632 - 2.3.1.16 5.733e-218 681.0
WLSH3_k127_852085_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 449.0
WLSH3_k127_852085_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 462.0
WLSH3_k127_852085_5 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 423.0
WLSH3_k127_852085_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 440.0
WLSH3_k127_852085_7 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001471 276.0
WLSH3_k127_852085_8 PFAM thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000000000000000000000000001322 214.0
WLSH3_k127_852085_9 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000003631 173.0
WLSH3_k127_8525233_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 564.0
WLSH3_k127_8525233_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 524.0
WLSH3_k127_8525233_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 412.0
WLSH3_k127_8525233_3 signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008328 281.0
WLSH3_k127_8525233_4 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000005393 248.0
WLSH3_k127_8525233_5 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000001035 224.0
WLSH3_k127_8525233_6 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000001921 176.0
WLSH3_k127_8525233_7 - - - - 0.00000000000000000000000000000000000000001586 156.0
WLSH3_k127_8525233_8 - - - - 0.00000000000000000000000000000000000000002564 156.0
WLSH3_k127_8525233_9 Belongs to the 'phage' integrase family - - - 0.00000001568 56.0
WLSH3_k127_8576315_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 6.144e-249 774.0
WLSH3_k127_8576315_1 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 1.111e-241 755.0
WLSH3_k127_8576315_2 PIN domain - - - 0.00000000000000000000000000000000000000000000000000000004393 198.0
WLSH3_k127_8576315_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000006408 114.0
WLSH3_k127_8713400_0 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 599.0
WLSH3_k127_8713400_1 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 527.0
WLSH3_k127_8713400_2 Peptidase family M48 - - - 0.00000000000000000000000000001298 119.0
WLSH3_k127_8713400_3 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000005591 99.0
WLSH3_k127_8770721_0 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 475.0
WLSH3_k127_8770721_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000002697 134.0
WLSH3_k127_8770721_2 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000005776 96.0
WLSH3_k127_879577_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1539.0
WLSH3_k127_879577_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 458.0
WLSH3_k127_879577_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 426.0
WLSH3_k127_879577_3 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 322.0
WLSH3_k127_879577_4 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000000000000476 140.0
WLSH3_k127_879577_5 - - - - 0.00000000000000000000000000004841 118.0
WLSH3_k127_879577_6 - - - - 0.0000000000000002992 79.0
WLSH3_k127_879577_7 - - - - 0.000006165 53.0
WLSH3_k127_8913412_0 RNB K01147 - 3.1.13.1 2.328e-299 928.0
WLSH3_k127_8913412_1 FeS assembly protein SufB K09014 - - 1.839e-286 882.0
WLSH3_k127_8913412_10 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 340.0
WLSH3_k127_8913412_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 302.0
WLSH3_k127_8913412_12 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 298.0
WLSH3_k127_8913412_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001727 278.0
WLSH3_k127_8913412_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004431 276.0
WLSH3_k127_8913412_15 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000000000263 214.0
WLSH3_k127_8913412_16 Transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000002111 212.0
WLSH3_k127_8913412_17 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000001592 162.0
WLSH3_k127_8913412_18 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000005151 158.0
WLSH3_k127_8913412_19 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000000002833 154.0
WLSH3_k127_8913412_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 1.251e-195 614.0
WLSH3_k127_8913412_20 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000295 151.0
WLSH3_k127_8913412_21 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000001144 124.0
WLSH3_k127_8913412_3 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 535.0
WLSH3_k127_8913412_4 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 411.0
WLSH3_k127_8913412_5 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 393.0
WLSH3_k127_8913412_6 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 394.0
WLSH3_k127_8913412_7 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 374.0
WLSH3_k127_8913412_8 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 364.0
WLSH3_k127_8913412_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 351.0
WLSH3_k127_8973018_0 Binding-protein-dependent transport system inner membrane component K02011 - - 4.506e-296 914.0
WLSH3_k127_8973018_1 Pfam:HipA_N K07154 - 2.7.11.1 1.608e-234 735.0
WLSH3_k127_8973018_10 Binding-protein-dependent transport system inner membrane component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 440.0
WLSH3_k127_8973018_11 ABC transporter K02049,K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 431.0
WLSH3_k127_8973018_12 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 381.0
WLSH3_k127_8973018_13 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 319.0
WLSH3_k127_8973018_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 310.0
WLSH3_k127_8973018_15 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 304.0
WLSH3_k127_8973018_16 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 291.0
WLSH3_k127_8973018_17 Uncharacterized conserved protein (DUF2075) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001124 256.0
WLSH3_k127_8973018_18 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009092 246.0
WLSH3_k127_8973018_19 ANTAR K07183 - - 0.000000000000000000000000000000000000000000000000000000000000000004418 230.0
WLSH3_k127_8973018_2 NMT1-like family K02051,K15576,K22067 - - 2.148e-233 728.0
WLSH3_k127_8973018_20 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000007374 209.0
WLSH3_k127_8973018_22 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000002323 210.0
WLSH3_k127_8973018_23 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000009056 200.0
WLSH3_k127_8973018_24 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.00000000000000000000000000000000000000000000000000000002489 200.0
WLSH3_k127_8973018_25 Eukaryotic integral membrane protein (DUF1751) - - - 0.00000000000000000000000000000000000000000000000000000002745 202.0
WLSH3_k127_8973018_27 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000009801 161.0
WLSH3_k127_8973018_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000001151 151.0
WLSH3_k127_8973018_29 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000002085 139.0
WLSH3_k127_8973018_3 Diguanylate cyclase - - - 7.78e-217 700.0
WLSH3_k127_8973018_30 Transcriptional regulator - - - 0.000000000000000000000000000000004933 129.0
WLSH3_k127_8973018_31 - - - - 0.00000000000000000000000004553 114.0
WLSH3_k127_8973018_32 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000003126 99.0
WLSH3_k127_8973018_33 - - - - 0.00000000000000000006485 93.0
WLSH3_k127_8973018_34 - - - - 0.0000000000000001511 83.0
WLSH3_k127_8973018_35 - - - - 0.0000000000000005161 83.0
WLSH3_k127_8973018_4 Dehydrogenase - - - 1.078e-194 615.0
WLSH3_k127_8973018_5 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 587.0
WLSH3_k127_8973018_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 537.0
WLSH3_k127_8973018_7 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 518.0
WLSH3_k127_8973018_8 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 504.0
WLSH3_k127_8973018_9 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 478.0
WLSH3_k127_8997957_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1588.0
WLSH3_k127_8997957_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1336.0
WLSH3_k127_8997957_10 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 595.0
WLSH3_k127_8997957_11 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 534.0
WLSH3_k127_8997957_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 520.0
WLSH3_k127_8997957_13 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 507.0
WLSH3_k127_8997957_14 PFAM permease YjgP YjgQ family protein K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 484.0
WLSH3_k127_8997957_15 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 479.0
WLSH3_k127_8997957_16 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 408.0
WLSH3_k127_8997957_17 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 386.0
WLSH3_k127_8997957_18 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 383.0
WLSH3_k127_8997957_19 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008651 355.0
WLSH3_k127_8997957_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1213.0
WLSH3_k127_8997957_20 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 351.0
WLSH3_k127_8997957_21 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002008 291.0
WLSH3_k127_8997957_22 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 271.0
WLSH3_k127_8997957_23 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000003656 244.0
WLSH3_k127_8997957_24 PFAM DNA polymerase III chi subunit HolC K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000002441 218.0
WLSH3_k127_8997957_25 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000009479 215.0
WLSH3_k127_8997957_26 OmpA family K03640 - - 0.0000000000000000000000000000000000000000000000000001769 190.0
WLSH3_k127_8997957_27 TolA C-terminal K03646 - - 0.000000000000000000000000000000001566 135.0
WLSH3_k127_8997957_28 Prokaryotic N-terminal methylation motif K02650 - - 0.00000000000000000000000000007199 124.0
WLSH3_k127_8997957_29 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000251 105.0
WLSH3_k127_8997957_3 PFAM thiamine pyrophosphate K01652 - 2.2.1.6 8.74e-322 991.0
WLSH3_k127_8997957_4 metal-dependent phosphohydrolase HD sub domain - - - 3.018e-251 786.0
WLSH3_k127_8997957_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.185e-208 648.0
WLSH3_k127_8997957_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 1.097e-207 656.0
WLSH3_k127_8997957_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.33e-201 632.0
WLSH3_k127_8997957_8 serine threonine protein kinase K12132 - 2.7.11.1 1.413e-199 629.0
WLSH3_k127_8997957_9 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 599.0
WLSH3_k127_9029002_0 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 0.0 1102.0
WLSH3_k127_9029002_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1060.0
WLSH3_k127_9029002_10 Highly conserved protein containing a thioredoxin domain K06888 - - 5.819e-201 643.0
WLSH3_k127_9029002_11 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 577.0
WLSH3_k127_9029002_12 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 555.0
WLSH3_k127_9029002_13 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 542.0
WLSH3_k127_9029002_14 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 523.0
WLSH3_k127_9029002_15 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 482.0
WLSH3_k127_9029002_16 LysM domain K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 494.0
WLSH3_k127_9029002_17 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 478.0
WLSH3_k127_9029002_18 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 466.0
WLSH3_k127_9029002_19 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 472.0
WLSH3_k127_9029002_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031,K02032 - - 5e-290 904.0
WLSH3_k127_9029002_20 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 448.0
WLSH3_k127_9029002_21 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 446.0
WLSH3_k127_9029002_22 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 431.0
WLSH3_k127_9029002_23 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 428.0
WLSH3_k127_9029002_24 PFAM glycine cleavage T protein (aminomethyl transferase) K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 427.0
WLSH3_k127_9029002_25 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 406.0
WLSH3_k127_9029002_26 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 407.0
WLSH3_k127_9029002_27 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 414.0
WLSH3_k127_9029002_28 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 390.0
WLSH3_k127_9029002_29 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 380.0
WLSH3_k127_9029002_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.191e-263 824.0
WLSH3_k127_9029002_30 LysR substrate binding domain K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 378.0
WLSH3_k127_9029002_31 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 364.0
WLSH3_k127_9029002_32 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 361.0
WLSH3_k127_9029002_33 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 356.0
WLSH3_k127_9029002_34 SpoU rRNA Methylase family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 338.0
WLSH3_k127_9029002_35 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 332.0
WLSH3_k127_9029002_36 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 328.0
WLSH3_k127_9029002_37 TIGRFAM Sua5 YciO YrdC YwlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 325.0
WLSH3_k127_9029002_38 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 327.0
WLSH3_k127_9029002_39 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 323.0
WLSH3_k127_9029002_4 May be involved in recombinational repair of damaged DNA K03631 - - 3.098e-259 808.0
WLSH3_k127_9029002_40 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 318.0
WLSH3_k127_9029002_41 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 315.0
WLSH3_k127_9029002_42 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003201 272.0
WLSH3_k127_9029002_43 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002728 264.0
WLSH3_k127_9029002_44 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003 251.0
WLSH3_k127_9029002_45 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004135 256.0
WLSH3_k127_9029002_46 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000001757 239.0
WLSH3_k127_9029002_47 Segregation and condensation complex subunit ScpB K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000001402 240.0
WLSH3_k127_9029002_48 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001507 235.0
WLSH3_k127_9029002_49 protein domain (DUF2202) - - - 0.000000000000000000000000000000000000000000000000000000000000000005278 231.0
WLSH3_k127_9029002_5 Sulfatase - - - 3.637e-238 753.0
WLSH3_k127_9029002_50 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000000000000000000001889 222.0
WLSH3_k127_9029002_51 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000002629 219.0
WLSH3_k127_9029002_52 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000003511 218.0
WLSH3_k127_9029002_53 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000004264 201.0
WLSH3_k127_9029002_54 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000002344 199.0
WLSH3_k127_9029002_55 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000001317 193.0
WLSH3_k127_9029002_56 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000003208 193.0
WLSH3_k127_9029002_57 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000004336 183.0
WLSH3_k127_9029002_58 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000000000000006147 181.0
WLSH3_k127_9029002_59 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000001351 176.0
WLSH3_k127_9029002_6 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 8.661e-237 734.0
WLSH3_k127_9029002_60 - - - - 0.00000000000000000000000000000008238 128.0
WLSH3_k127_9029002_61 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000001719 126.0
WLSH3_k127_9029002_62 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000001508 117.0
WLSH3_k127_9029002_63 Trm112p-like protein K09791 - - 0.000000000000000000000000002716 111.0
WLSH3_k127_9029002_64 Cysteine-rich domain - - - 0.000000000001103 68.0
WLSH3_k127_9029002_7 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.141e-234 730.0
WLSH3_k127_9029002_8 Cysteine-rich domain - - - 5.452e-222 694.0
WLSH3_k127_9029002_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 1.399e-201 637.0
WLSH3_k127_9099754_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 0.0 1212.0
WLSH3_k127_9099754_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1048.0
WLSH3_k127_9099754_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 315.0
WLSH3_k127_9099754_11 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 300.0
WLSH3_k127_9099754_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 297.0
WLSH3_k127_9099754_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 293.0
WLSH3_k127_9099754_14 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 285.0
WLSH3_k127_9099754_15 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000001438 251.0
WLSH3_k127_9099754_16 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000008577 247.0
WLSH3_k127_9099754_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001451 239.0
WLSH3_k127_9099754_18 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000002403 204.0
WLSH3_k127_9099754_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000001977 171.0
WLSH3_k127_9099754_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.063e-268 832.0
WLSH3_k127_9099754_20 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000000001145 136.0
WLSH3_k127_9099754_21 PFAM glycosyl transferase group 1 - - - 0.00004346 49.0
WLSH3_k127_9099754_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.44e-255 790.0
WLSH3_k127_9099754_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.307e-248 769.0
WLSH3_k127_9099754_5 Ammonium Transporter Family K03320,K06580 - - 1.028e-235 731.0
WLSH3_k127_9099754_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.822e-225 706.0
WLSH3_k127_9099754_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 583.0
WLSH3_k127_9099754_8 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 393.0
WLSH3_k127_9099754_9 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 376.0
WLSH3_k127_9161623_0 Sucrose synthase K00696 - 2.4.1.14 0.0 1055.0
WLSH3_k127_9161623_1 PFAM Alpha amylase, catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 1.679e-207 649.0
WLSH3_k127_9161623_2 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 565.0
WLSH3_k127_9161623_3 TIGRFAM TIGR03790 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 430.0
WLSH3_k127_9161623_4 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 392.0
WLSH3_k127_9161623_5 PfkB domain protein K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 356.0
WLSH3_k127_9161623_6 HAD-superfamily hydrolase, subfamily IIB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 329.0
WLSH3_k127_9161623_7 response regulator K02479,K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000006666 225.0
WLSH3_k127_9161623_8 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000001128 216.0
WLSH3_k127_9161623_9 Protein of unknown function (DUF642) - - - 0.00000009266 61.0
WLSH3_k127_9172077_0 ABC transporter transmembrane region K06147 - - 8.247e-231 724.0
WLSH3_k127_9172077_1 PFAM glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 329.0
WLSH3_k127_9172077_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 297.0
WLSH3_k127_9172077_3 Protein of unknown function (DUF3530) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001815 277.0
WLSH3_k127_9172077_4 MltA-interacting protein MipA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001047 258.0
WLSH3_k127_9172077_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000000000000002953 144.0
WLSH3_k127_9172077_6 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000003624 106.0
WLSH3_k127_9179385_0 Citrate transporter - - - 3.462e-243 762.0
WLSH3_k127_9179385_1 Von Willebrand factor type A K07114 - - 5.95e-204 651.0
WLSH3_k127_9179385_10 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000000000000000000000000000000000008902 169.0
WLSH3_k127_9179385_11 Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein K07213,K08364 - - 0.000000000000000000000000000002362 123.0
WLSH3_k127_9179385_12 - - - - 0.00000000000000000000000000002521 121.0
WLSH3_k127_9179385_13 Immunity protein 53 - - - 0.0000000000000000000000003725 107.0
WLSH3_k127_9179385_14 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000008142 98.0
WLSH3_k127_9179385_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000009756 84.0
WLSH3_k127_9179385_16 DnaJ molecular chaperone homology domain - - - 0.00000000000000005919 90.0
WLSH3_k127_9179385_17 Sel1-like repeats. K07126 - - 0.0000000000000001981 84.0
WLSH3_k127_9179385_2 PFAM ABC transporter related K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 408.0
WLSH3_k127_9179385_3 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 398.0
WLSH3_k127_9179385_4 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 337.0
WLSH3_k127_9179385_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003706 267.0
WLSH3_k127_9179385_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004729 238.0
WLSH3_k127_9179385_7 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000005498 246.0
WLSH3_k127_9179385_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000001329 175.0
WLSH3_k127_9179385_9 mercuric transport protein K08363 - - 0.00000000000000000000000000000000000000000000002886 173.0
WLSH3_k127_9215140_0 heat shock protein binding - - - 1.575e-287 893.0
WLSH3_k127_9215140_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 5.814e-205 644.0
WLSH3_k127_9215140_10 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000000000007569 186.0
WLSH3_k127_9215140_11 - - - - 0.00000000000000000000006694 104.0
WLSH3_k127_9215140_12 - - - - 0.000000000001736 78.0
WLSH3_k127_9215140_13 Transposase (IS116 IS110 IS902 family) - - - 0.000000291 52.0
WLSH3_k127_9215140_14 addiction module toxin, RelE StbE family - - - 0.000001063 55.0
WLSH3_k127_9215140_2 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 597.0
WLSH3_k127_9215140_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 454.0
WLSH3_k127_9215140_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 398.0
WLSH3_k127_9215140_5 ferredoxin-NADP+ reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 327.0
WLSH3_k127_9215140_6 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 309.0
WLSH3_k127_9215140_7 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 302.0
WLSH3_k127_9215140_8 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000004516 241.0
WLSH3_k127_9215140_9 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000001176 229.0
WLSH3_k127_9276876_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1247.0
WLSH3_k127_9276876_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 5.645e-275 855.0
WLSH3_k127_9276876_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 551.0
WLSH3_k127_9276876_11 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 535.0
WLSH3_k127_9276876_12 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 531.0
WLSH3_k127_9276876_13 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 524.0
WLSH3_k127_9276876_14 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 511.0
WLSH3_k127_9276876_15 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 471.0
WLSH3_k127_9276876_16 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 465.0
WLSH3_k127_9276876_17 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 450.0
WLSH3_k127_9276876_18 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 428.0
WLSH3_k127_9276876_19 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 412.0
WLSH3_k127_9276876_2 Mur ligase family, catalytic domain K01924 - 6.3.2.8 1.243e-235 738.0
WLSH3_k127_9276876_20 receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 426.0
WLSH3_k127_9276876_21 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 395.0
WLSH3_k127_9276876_22 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 379.0
WLSH3_k127_9276876_23 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 291.0
WLSH3_k127_9276876_24 MraZ protein, putative antitoxin-like K03925 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003538 242.0
WLSH3_k127_9276876_25 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000714 240.0
WLSH3_k127_9276876_26 regulator K18831 - - 0.0000000000000000000000000000000000000000000000000000000000000009162 220.0
WLSH3_k127_9276876_27 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000002077 227.0
WLSH3_k127_9276876_28 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.000000000000000000000000000000000000000000000000002564 182.0
WLSH3_k127_9276876_29 - - - - 0.00000000000000000000000000000000000000000000009371 174.0
WLSH3_k127_9276876_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 1.881e-221 697.0
WLSH3_k127_9276876_30 Cell division protein ZapA K09888 - - 0.0000000000000000000000000000000000000000000005143 167.0
WLSH3_k127_9276876_31 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000002261 132.0
WLSH3_k127_9276876_32 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000000000003093 119.0
WLSH3_k127_9276876_33 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000005501 85.0
WLSH3_k127_9276876_34 - - - - 0.000000000000005922 77.0
WLSH3_k127_9276876_35 - - - - 0.0000000000006878 70.0
WLSH3_k127_9276876_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.222e-216 677.0
WLSH3_k127_9276876_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.343e-200 633.0
WLSH3_k127_9276876_6 PFAM Type II secretion system F domain K02653 - - 6.613e-199 625.0
WLSH3_k127_9276876_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 3.048e-198 624.0
WLSH3_k127_9276876_8 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 605.0
WLSH3_k127_9276876_9 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 554.0
WLSH3_k127_933945_0 Acyl-CoA dehydrogenase, N-terminal domain K06445 - - 0.0 1210.0
WLSH3_k127_933945_1 associated with various cellular activities - - - 1.328e-210 656.0
WLSH3_k127_933945_10 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000001145 78.0
WLSH3_k127_933945_2 Putative metallopeptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 603.0
WLSH3_k127_933945_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006343 518.0
WLSH3_k127_933945_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 497.0
WLSH3_k127_933945_5 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 453.0
WLSH3_k127_933945_6 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 384.0
WLSH3_k127_933945_7 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 390.0
WLSH3_k127_933945_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 351.0
WLSH3_k127_933945_9 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000005045 143.0
WLSH3_k127_9423188_0 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 587.0
WLSH3_k127_9423188_1 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 538.0
WLSH3_k127_9423188_10 GlcNAc-PI de-N-acetylase - - - 0.0000001464 64.0
WLSH3_k127_9423188_11 peptidyl-tyrosine sulfation - - - 0.00006684 55.0
WLSH3_k127_9423188_2 histidine kinase A domain protein K07679 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 461.0
WLSH3_k127_9423188_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 409.0
WLSH3_k127_9423188_4 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 390.0
WLSH3_k127_9423188_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 306.0
WLSH3_k127_9423188_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003497 270.0
WLSH3_k127_9423188_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000003982 203.0
WLSH3_k127_9423188_8 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000000000000000007445 207.0
WLSH3_k127_9423188_9 peptidyl-tyrosine sulfation - - - 0.0000000005357 72.0
WLSH3_k127_9489008_0 Histidine kinase K20974 - 2.7.13.3 0.0 1176.0
WLSH3_k127_9489008_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 1.057e-226 714.0
WLSH3_k127_9489008_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 8.736e-201 629.0
WLSH3_k127_9489008_3 Urea ABC transporter, urea binding protein K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
WLSH3_k127_9489008_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008633 456.0
WLSH3_k127_9489008_5 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001559 279.0
WLSH3_k127_9489008_6 Histidine kinase K07679 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000508 309.0
WLSH3_k127_9489008_7 Sigma factor PP2C-like phosphatases K20977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001406 271.0
WLSH3_k127_9489008_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000001781 157.0
WLSH3_k127_9489008_9 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000002683 123.0
WLSH3_k127_952404_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 539.0
WLSH3_k127_952404_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 340.0
WLSH3_k127_952404_2 - - - - 0.0000000000000000000000000000000000000000000000000000000005578 207.0
WLSH3_k127_9580830_0 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
WLSH3_k127_9580830_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001923 264.0
WLSH3_k127_9580830_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004261 256.0
WLSH3_k127_9672500_0 Respiratory nitrate reductase alpha N-terminal K00370 - 1.7.5.1 0.0 2256.0
WLSH3_k127_9672500_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1851.0
WLSH3_k127_9672500_10 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 370.0
WLSH3_k127_9672500_11 PFAM HPP family protein K07168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 364.0
WLSH3_k127_9672500_12 Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 340.0
WLSH3_k127_9672500_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 290.0
WLSH3_k127_9672500_14 helix_turn_helix, Lux Regulon K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 288.0
WLSH3_k127_9672500_15 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002118 284.0
WLSH3_k127_9672500_16 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004169 265.0
WLSH3_k127_9672500_17 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005327 252.0
WLSH3_k127_9672500_18 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007656 241.0
WLSH3_k127_9672500_19 Regulatory protein MarR - - - 0.00000000000000000000000000000000000000000000000000000000000000000002857 235.0
WLSH3_k127_9672500_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 1.25e-304 938.0
WLSH3_k127_9672500_20 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002543 235.0
WLSH3_k127_9672500_21 COG1226 Kef-type K transport systems K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
WLSH3_k127_9672500_22 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000269 207.0
WLSH3_k127_9672500_23 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000000000000000002466 204.0
WLSH3_k127_9672500_24 - - - - 0.000000000000000000000000000000000000000000000000000000207 197.0
WLSH3_k127_9672500_25 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001364 182.0
WLSH3_k127_9672500_26 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000003618 171.0
WLSH3_k127_9672500_27 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000000000000000000003586 161.0
WLSH3_k127_9672500_28 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.000000000000000000000000000000000003874 139.0
WLSH3_k127_9672500_29 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000001095 136.0
WLSH3_k127_9672500_3 nitrate nitrite transporter K02575 - - 5.004e-257 796.0
WLSH3_k127_9672500_31 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000006282 102.0
WLSH3_k127_9672500_32 PFAM Plasmid maintenance system killer K07334 - - 0.000000000000000009543 84.0
WLSH3_k127_9672500_33 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000001624 87.0
WLSH3_k127_9672500_34 Putative addiction module component - - - 0.00000000001954 67.0
WLSH3_k127_9672500_35 Protein of unknown function (DUF2934) - - - 0.0000000003601 67.0
WLSH3_k127_9672500_4 Major Facilitator Superfamily K02575 - - 1.38e-229 717.0
WLSH3_k127_9672500_5 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 588.0
WLSH3_k127_9672500_6 GAF domain K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 589.0
WLSH3_k127_9672500_7 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 463.0
WLSH3_k127_9672500_8 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 425.0
WLSH3_k127_9672500_9 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 426.0
WLSH3_k127_9719866_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1199.0
WLSH3_k127_9719866_1 SMART GGDEF domain containing protein - - - 4.033e-204 655.0
WLSH3_k127_9719866_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 498.0
WLSH3_k127_9719866_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 419.0
WLSH3_k127_9719866_4 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 306.0
WLSH3_k127_9719866_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 302.0
WLSH3_k127_9855163_0 TonB dependent receptor K02014 - - 4.055e-254 803.0
WLSH3_k127_9855163_1 Peptidase M14, carboxypeptidase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 582.0
WLSH3_k127_9855163_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 447.0
WLSH3_k127_9855163_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 359.0
WLSH3_k127_9855163_4 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 331.0
WLSH3_k127_9855163_5 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001276 253.0
WLSH3_k127_9855163_6 Acyltransferase - - - 0.000000000000000000000000000000000000000005059 161.0
WLSH3_k127_9855163_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000007214 150.0
WLSH3_k127_9855163_8 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000002064 146.0
WLSH3_k127_9855163_9 BNR repeat-like domain - - - 0.0005081 44.0
WLSH3_k127_9965829_0 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 317.0
WLSH3_k127_9965829_1 - - - - 0.000000000000000000000001388 107.0
WLSH3_k127_9965829_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000001062 64.0
WLSH3_k127_9965829_3 phosphoserine phosphatase - - - 0.00000000267 57.0
WLSH3_k127_9977277_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 2.137e-291 904.0
WLSH3_k127_9977277_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 4.15e-217 679.0
WLSH3_k127_9977277_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000004806 233.0
WLSH3_k127_9977277_3 Indole-3-glycerol phosphate synthase K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000001568 219.0
WLSH3_k127_9977277_4 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000002411 187.0
WLSH3_k127_9977277_5 PFAM porin Gram-negative type - - - 0.000000000000009219 80.0