Overview

ID MAG04239
Name WLSH3_bin.2
Sample SMP0111
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family Methanospirillaceae
Genus Methanoregula
Species
Assembly information
Completeness (%) 89.36
Contamination (%) 6.55
GC content (%) 50.0
N50 (bp) 11,432
Genome size (bp) 2,163,022

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2212

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH3_k127_10002177_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1407.0
WLSH3_k127_10002177_1 acid binding OB-fold tRNA helicase-type K07463 - - 0.0 1087.0
WLSH3_k127_10002177_10 adenyl ribonucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001922 252.0
WLSH3_k127_10002177_11 B-block binding subunit of TFIIIC - - - 0.000000000000000000000000000000000000000000000000000000000008578 208.0
WLSH3_k127_10002177_12 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000002117 205.0
WLSH3_k127_10002177_13 Family of unknown function (DUF5328) - - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
WLSH3_k127_10002177_14 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000252 180.0
WLSH3_k127_10002177_15 - - - - 0.00000000000000000000000000000000000000000001375 162.0
WLSH3_k127_10002177_16 - - - - 0.00000000000000000000000000000000000000006542 156.0
WLSH3_k127_10002177_17 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000000000000000000000909 149.0
WLSH3_k127_10002177_18 - - - - 0.000000000000000000000003928 104.0
WLSH3_k127_10002177_19 - - - - 0.000000000007808 70.0
WLSH3_k127_10002177_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.397e-257 797.0
WLSH3_k127_10002177_20 membrane K08978 - - 0.0001516 48.0
WLSH3_k127_10002177_3 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 2.321e-227 716.0
WLSH3_k127_10002177_4 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 1.73e-202 633.0
WLSH3_k127_10002177_5 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 3.128e-196 616.0
WLSH3_k127_10002177_6 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 514.0
WLSH3_k127_10002177_7 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 448.0
WLSH3_k127_10002177_8 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 409.0
WLSH3_k127_10002177_9 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
WLSH3_k127_10004446_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1106.0
WLSH3_k127_10004446_1 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 597.0
WLSH3_k127_10004446_10 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000003319 132.0
WLSH3_k127_10004446_11 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000000000000000000002445 124.0
WLSH3_k127_10004446_12 - - - - 0.000000000000000000000000007956 111.0
WLSH3_k127_10004446_13 DGC domain - - - 0.00000000000000000000000001122 113.0
WLSH3_k127_10004446_14 Cupin 2 conserved barrel domain - - - 0.00000000000000000000000001442 111.0
WLSH3_k127_10004446_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 561.0
WLSH3_k127_10004446_3 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 449.0
WLSH3_k127_10004446_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 378.0
WLSH3_k127_10004446_5 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 308.0
WLSH3_k127_10004446_6 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 304.0
WLSH3_k127_10004446_7 DGC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001028 242.0
WLSH3_k127_10004446_8 - - - - 0.00000000000000000000000000000000000000000000000000000000007039 207.0
WLSH3_k127_10004446_9 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000009567 144.0
WLSH3_k127_10031086_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 603.0
WLSH3_k127_10031086_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 349.0
WLSH3_k127_10031086_2 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000000000000000000000000000003279 236.0
WLSH3_k127_10031086_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000001632 158.0
WLSH3_k127_10031086_4 - - - - 0.00000000000000000000000000000000006783 140.0
WLSH3_k127_10031086_5 - - - - 0.000000000000009754 76.0
WLSH3_k127_10090378_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.219e-283 880.0
WLSH3_k127_10090378_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 1.642e-206 643.0
WLSH3_k127_10090378_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000000000000000000000000000003744 138.0
WLSH3_k127_10090378_11 - - - - 0.0000000000000000000001239 103.0
WLSH3_k127_10090378_12 COG1042 Acyl-CoA synthetase (NDP forming) K09181 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 - 0.0004488 47.0
WLSH3_k127_10090378_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 402.0
WLSH3_k127_10090378_3 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 365.0
WLSH3_k127_10090378_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001792 248.0
WLSH3_k127_10090378_5 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.000000000000000000000000000000000000000000000000000000000000000004251 228.0
WLSH3_k127_10090378_6 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000000000000000000000000004547 222.0
WLSH3_k127_10090378_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007974 234.0
WLSH3_k127_10090378_8 PFAM ribosomal protein S8E K02995 - - 0.0000000000000000000000000000000000000000000000000000000001974 205.0
WLSH3_k127_10090378_9 RNA-binding protein involved in rRNA processing K07569 - - 0.000000000000000000000000000000000000001829 147.0
WLSH3_k127_10252835_0 PFAM ABC-1 domain protein K03688 - - 1.147e-281 874.0
WLSH3_k127_10252835_1 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 584.0
WLSH3_k127_10252835_10 Acetyltransferase (GNAT) domain K03824 - - 0.000000000000000000000000000000000000000000000000000000000000000245 225.0
WLSH3_k127_10252835_11 transcription activator, effector binding - - - 0.000000000000000000000000000000000000000000000000000000002579 205.0
WLSH3_k127_10252835_12 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000002299 168.0
WLSH3_k127_10252835_13 PFAM Ribonuclease III K03685 - 3.1.26.3 0.000000000000000000000000000000000000000002037 164.0
WLSH3_k127_10252835_14 Uracil DNA glycosylase superfamily K03649 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097507,GO:0140097,GO:1901360 3.2.2.28 0.00000000000000000000000000000000000000003264 158.0
WLSH3_k127_10252835_15 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.000000000000000000000000000000000007625 139.0
WLSH3_k127_10252835_16 PAS domain - - - 0.000000000000000000000003383 116.0
WLSH3_k127_10252835_17 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000002 52.0
WLSH3_k127_10252835_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 533.0
WLSH3_k127_10252835_3 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 411.0
WLSH3_k127_10252835_4 TIGRFAM F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 392.0
WLSH3_k127_10252835_5 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 383.0
WLSH3_k127_10252835_6 MCP methyltransferase, CheR-type K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 369.0
WLSH3_k127_10252835_7 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 321.0
WLSH3_k127_10252835_8 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 310.0
WLSH3_k127_10252835_9 PAS domain K02030,K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000183 243.0
WLSH3_k127_10342923_0 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 3.776e-231 721.0
WLSH3_k127_10342923_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 344.0
WLSH3_k127_10342923_2 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
WLSH3_k127_10342923_3 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000007108 187.0
WLSH3_k127_10342923_4 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000002929 171.0
WLSH3_k127_10342923_5 - - - - 0.00000000000000000000000000000007862 126.0
WLSH3_k127_10342923_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000008894 112.0
WLSH3_k127_10379558_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1276.0
WLSH3_k127_10379558_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.0 1088.0
WLSH3_k127_10379558_10 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 484.0
WLSH3_k127_10379558_11 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 487.0
WLSH3_k127_10379558_12 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 449.0
WLSH3_k127_10379558_13 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 425.0
WLSH3_k127_10379558_14 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 381.0
WLSH3_k127_10379558_15 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 389.0
WLSH3_k127_10379558_16 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
WLSH3_k127_10379558_17 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 372.0
WLSH3_k127_10379558_18 COGs COG0614 ABC-type Fe3 -hydroxamate transport system periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 319.0
WLSH3_k127_10379558_19 PFAM ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 315.0
WLSH3_k127_10379558_2 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.0 1018.0
WLSH3_k127_10379558_20 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 295.0
WLSH3_k127_10379558_21 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003445 281.0
WLSH3_k127_10379558_22 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000007553 259.0
WLSH3_k127_10379558_23 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007209 256.0
WLSH3_k127_10379558_24 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000001736 228.0
WLSH3_k127_10379558_25 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001663 237.0
WLSH3_k127_10379558_26 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000001308 183.0
WLSH3_k127_10379558_27 Regulatory protein MarR - - - 0.0000000000000000000000000000000000000000000000002678 181.0
WLSH3_k127_10379558_28 COG1321 Mn-dependent transcriptional regulator K03709 - - 0.0000000000000000000000000000000000000000000007078 169.0
WLSH3_k127_10379558_29 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.0000000000000000000000000000000000000000004926 158.0
WLSH3_k127_10379558_3 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 1.18e-269 832.0
WLSH3_k127_10379558_30 Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000000000000000000000000000000004415 148.0
WLSH3_k127_10379558_31 Belongs to the UPF0251 family K06933 - - 0.000000000000000000000000000000005882 132.0
WLSH3_k127_10379558_32 methanogenesis marker protein 11 - - - 0.000000000000000000000000000003628 121.0
WLSH3_k127_10379558_34 PFAM FeoA family protein K04758 - - 0.0000000000002621 74.0
WLSH3_k127_10379558_4 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 5.907e-262 810.0
WLSH3_k127_10379558_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 3.766e-238 739.0
WLSH3_k127_10379558_6 Ferrous iron transport B domain protein K04759 - - 4.757e-237 745.0
WLSH3_k127_10379558_7 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 560.0
WLSH3_k127_10379558_8 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 544.0
WLSH3_k127_10379558_9 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 527.0
WLSH3_k127_10382702_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 384.0
WLSH3_k127_10382702_1 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000001592 204.0
WLSH3_k127_10382702_2 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000135 73.0
WLSH3_k127_10396516_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1294.0
WLSH3_k127_10396516_1 SMART Elongator protein 3 MiaB NifB K22227 - - 9.068e-195 611.0
WLSH3_k127_10396516_10 Protein of unknown function (DUF3795) - - - 0.00000000000000000664 86.0
WLSH3_k127_10396516_11 Zinc-binding dehydrogenase - - - 0.0000003248 52.0
WLSH3_k127_10396516_2 YoaP-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 420.0
WLSH3_k127_10396516_3 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 363.0
WLSH3_k127_10396516_4 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006091 253.0
WLSH3_k127_10396516_5 Flavodoxin - GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000004308 192.0
WLSH3_k127_10396516_6 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000000000000000000001009 168.0
WLSH3_k127_10396516_8 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000009582 111.0
WLSH3_k127_10396516_9 - - - - 0.000000000000000000353 88.0
WLSH3_k127_10447786_0 PFAM DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008215 268.0
WLSH3_k127_10447786_1 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008675 267.0
WLSH3_k127_10447786_2 CBS domain K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000002197 232.0
WLSH3_k127_10447786_3 Protein of unknown function (DUF2769) - - - 0.000000000000112 71.0
WLSH3_k127_10584633_0 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000001401 173.0
WLSH3_k127_10584633_1 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000003261 117.0
WLSH3_k127_10584633_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000002726 66.0
WLSH3_k127_10616310_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 2.866e-201 632.0
WLSH3_k127_10616310_1 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000009147 124.0
WLSH3_k127_10751328_0 PFAM major facilitator superfamily MFS_1 - - - 9.262e-200 631.0
WLSH3_k127_10751328_1 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 507.0
WLSH3_k127_10751328_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000187 258.0
WLSH3_k127_10775389_0 Shikimate kinase K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000008868 221.0
WLSH3_k127_10775389_1 Transglutaminase-like superfamily - - - 0.0000000000000009097 85.0
WLSH3_k127_10791860_0 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 487.0
WLSH3_k127_10791860_1 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006642 265.0
WLSH3_k127_10791860_2 Multicopper oxidase - - - 0.000000000000000000000009048 102.0
WLSH3_k127_10800131_0 PFAM glutamate--cysteine ligase, GCS2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 276.0
WLSH3_k127_10800131_1 Membrane - - - 0.00000000000000000000000000000000000000000003412 171.0
WLSH3_k127_10800131_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000832 164.0
WLSH3_k127_10830287_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 440.0
WLSH3_k127_10830287_1 PFAM formate nitrite transporter K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 422.0
WLSH3_k127_10830287_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
WLSH3_k127_1091757_0 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 335.0
WLSH3_k127_1091757_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
WLSH3_k127_1091757_2 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 293.0
WLSH3_k127_1091757_3 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005583 233.0
WLSH3_k127_1091757_4 - - - - 0.0000000000000000000000000000000000000000000000000000004374 209.0
WLSH3_k127_10948375_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 433.0
WLSH3_k127_10948375_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 392.0
WLSH3_k127_10948375_2 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 364.0
WLSH3_k127_10948375_3 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 311.0
WLSH3_k127_10948375_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 288.0
WLSH3_k127_10948375_5 TIR domain - - - 0.00000000000000000000000000000000000000000007109 165.0
WLSH3_k127_10948375_6 Sugar efflux transporter for intercellular exchange K15383 - - 0.000000000000000000000000000001446 122.0
WLSH3_k127_10963215_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1643.0
WLSH3_k127_10963215_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.255e-258 804.0
WLSH3_k127_10963215_10 PFAM RDD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000001739 214.0
WLSH3_k127_10963215_11 - - - - 0.000000000000000000000000000000000000000005133 157.0
WLSH3_k127_10963215_12 Belongs to the UPF0146 family K09713 - - 0.000000000000000000000000000000000000000006728 157.0
WLSH3_k127_10963215_13 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000001554 120.0
WLSH3_k127_10963215_14 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000006655 76.0
WLSH3_k127_10963215_15 - - - - 0.00000000005365 65.0
WLSH3_k127_10963215_16 PFAM blue (type 1) copper domain protein - - - 0.000005602 56.0
WLSH3_k127_10963215_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 8.926e-210 661.0
WLSH3_k127_10963215_3 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005856 572.0
WLSH3_k127_10963215_4 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 384.0
WLSH3_k127_10963215_5 PFAM TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 353.0
WLSH3_k127_10963215_6 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003273 280.0
WLSH3_k127_10963215_7 PFAM peptidase zinc-dependent K06974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005072 263.0
WLSH3_k127_10963215_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001249 249.0
WLSH3_k127_10963215_9 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000004629 239.0
WLSH3_k127_11018930_0 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 318.0
WLSH3_k127_11019654_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 481.0
WLSH3_k127_11019654_1 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 417.0
WLSH3_k127_11019654_2 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 389.0
WLSH3_k127_11019654_3 protein conserved in archaea - - - 0.00000000000000000000000000000000000000000000000000000000000000000001259 239.0
WLSH3_k127_11019654_4 - - - - 0.00000000000000000000000000000000000000000004188 165.0
WLSH3_k127_11044573_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1364.0
WLSH3_k127_11044573_1 PFAM Aminotransferase class I and II K05825 - - 1.135e-203 639.0
WLSH3_k127_11044573_10 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001604 245.0
WLSH3_k127_11044573_11 TIGRFAM Small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000001563 205.0
WLSH3_k127_11044573_12 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000003925 161.0
WLSH3_k127_11044573_2 PhoU domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 514.0
WLSH3_k127_11044573_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 389.0
WLSH3_k127_11044573_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 320.0
WLSH3_k127_11044573_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 321.0
WLSH3_k127_11044573_6 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 286.0
WLSH3_k127_11044573_7 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008898 276.0
WLSH3_k127_11044573_8 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005118 256.0
WLSH3_k127_11044573_9 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000001236 243.0
WLSH3_k127_11095863_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 9.914e-204 640.0
WLSH3_k127_11095863_1 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 574.0
WLSH3_k127_11095863_2 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 489.0
WLSH3_k127_11095863_3 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 339.0
WLSH3_k127_11095863_4 ribosomal protein S15 K02956 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000154 258.0
WLSH3_k127_11095863_5 - - - - 0.0000000000000000001005 93.0
WLSH3_k127_11110088_0 COG1668 ABC-type Na efflux pump, permease component - - - 5.935e-285 885.0
WLSH3_k127_11110088_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 1.464e-226 712.0
WLSH3_k127_11110088_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 545.0
WLSH3_k127_11110088_3 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 514.0
WLSH3_k127_11110088_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 293.0
WLSH3_k127_11110088_5 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000008565 177.0
WLSH3_k127_11110088_6 - - - - 0.000000000000000000000000000000000002812 141.0
WLSH3_k127_11110088_7 zinc finger - - - 0.0000000000000000000000000000001722 126.0
WLSH3_k127_11149381_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 1.049e-214 672.0
WLSH3_k127_11149381_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 4.724e-203 640.0
WLSH3_k127_11149381_10 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000002361 211.0
WLSH3_k127_11149381_11 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000000000003327 179.0
WLSH3_k127_11149381_12 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000699 140.0
WLSH3_k127_11149381_13 Protein of unknown function (DUF2769) - - - 0.000000000000000000000000000008252 120.0
WLSH3_k127_11149381_14 Phosphopantetheine attachment site - - - 0.00000000000000003234 83.0
WLSH3_k127_11149381_15 monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.000000000003282 73.0
WLSH3_k127_11149381_16 - K05570 - - 0.000001741 53.0
WLSH3_k127_11149381_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 507.0
WLSH3_k127_11149381_3 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 417.0
WLSH3_k127_11149381_4 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 396.0
WLSH3_k127_11149381_5 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 417.0
WLSH3_k127_11149381_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 341.0
WLSH3_k127_11149381_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 327.0
WLSH3_k127_11149381_8 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000001663 226.0
WLSH3_k127_11149381_9 Domain of unknown function (DUF1724) - - - 0.0000000000000000000000000000000000000000000000000000000001831 213.0
WLSH3_k127_11201038_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.137e-314 967.0
WLSH3_k127_11201038_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 399.0
WLSH3_k127_11213456_0 KH, type 1, domain K07041 - - 0.0 1232.0
WLSH3_k127_11213456_1 TIGRFAM 26S proteasome subunit P45 family K03420 - - 8.266e-215 670.0
WLSH3_k127_11213456_10 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 349.0
WLSH3_k127_11213456_11 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 325.0
WLSH3_k127_11213456_12 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 306.0
WLSH3_k127_11213456_13 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 300.0
WLSH3_k127_11213456_14 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006379 269.0
WLSH3_k127_11213456_15 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.0000000000000000000000000000000000000000000000000000000000000000000000001001 252.0
WLSH3_k127_11213456_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003622 239.0
WLSH3_k127_11213456_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
WLSH3_k127_11213456_18 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000001219 234.0
WLSH3_k127_11213456_19 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
WLSH3_k127_11213456_2 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 497.0
WLSH3_k127_11213456_20 COG0589 Universal stress protein UspA and related nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000006734 201.0
WLSH3_k127_11213456_21 - - - - 0.000000000000000000000000000000000000000000000000000005711 194.0
WLSH3_k127_11213456_22 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000000000000000007899 186.0
WLSH3_k127_11213456_24 - - - - 0.0000000000000000000000000000000000002929 144.0
WLSH3_k127_11213456_25 but it may be involved in stabilization of the trimeric complex - - - 0.00000000000000000000002057 100.0
WLSH3_k127_11213456_26 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.00000000000000000000245 93.0
WLSH3_k127_11213456_27 PFAM TPR repeat-containing protein - - - 0.000000000000000005761 87.0
WLSH3_k127_11213456_28 PFAM major facilitator superfamily MFS_1 - - - 0.000000001774 59.0
WLSH3_k127_11213456_3 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 486.0
WLSH3_k127_11213456_30 PFAM Major Facilitator Superfamily - - - 0.00000109 51.0
WLSH3_k127_11213456_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 464.0
WLSH3_k127_11213456_5 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 464.0
WLSH3_k127_11213456_6 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 403.0
WLSH3_k127_11213456_7 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 401.0
WLSH3_k127_11213456_8 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 378.0
WLSH3_k127_11213456_9 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 370.0
WLSH3_k127_11233786_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1206.0
WLSH3_k127_11233786_1 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 536.0
WLSH3_k127_11233786_2 TIGRFAM PAS sensor protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 468.0
WLSH3_k127_11233786_3 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 312.0
WLSH3_k127_11233786_4 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003254 263.0
WLSH3_k127_11233786_5 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000205 208.0
WLSH3_k127_11233786_6 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000005694 194.0
WLSH3_k127_11233786_7 - - - - 0.00000000000000000000000000000000001413 137.0
WLSH3_k127_11233786_8 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000346 95.0
WLSH3_k127_11233786_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000003079 51.0
WLSH3_k127_11297461_0 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 308.0
WLSH3_k127_11297461_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000003533 245.0
WLSH3_k127_11297461_2 Tetratricopeptide repeat - - - 0.000000000000002593 79.0
WLSH3_k127_11342016_0 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 349.0
WLSH3_k127_11342016_1 integral membrane protein - - - 0.00000000000000000000000001753 117.0
WLSH3_k127_11342016_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000002512 63.0
WLSH3_k127_11368269_0 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 8.784e-234 725.0
WLSH3_k127_11368269_1 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 462.0
WLSH3_k127_11368269_2 - - - - 0.000000000000000000000000000000000000000000000000007922 188.0
WLSH3_k127_11368269_3 archaeal Zn-finger protein - - - 0.000000000000000000000000004393 110.0
WLSH3_k127_11368269_4 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000006995 109.0
WLSH3_k127_11368269_5 - - - - 0.0005693 43.0
WLSH3_k127_11394773_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.061e-233 732.0
WLSH3_k127_11394773_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 2.368e-229 722.0
WLSH3_k127_11394773_10 PAS domain K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 401.0
WLSH3_k127_11394773_11 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 340.0
WLSH3_k127_11394773_12 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 290.0
WLSH3_k127_11394773_13 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000204 269.0
WLSH3_k127_11394773_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001007 254.0
WLSH3_k127_11394773_15 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000002122 244.0
WLSH3_k127_11394773_16 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001312 246.0
WLSH3_k127_11394773_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000002912 239.0
WLSH3_k127_11394773_18 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000001897 232.0
WLSH3_k127_11394773_19 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000003356 215.0
WLSH3_k127_11394773_2 PFAM Cation K03498 - - 4.016e-229 717.0
WLSH3_k127_11394773_20 - - - - 0.000000000000000000000000000000000000000000000000000001255 201.0
WLSH3_k127_11394773_21 PFAM TspO MBR family K05770 - - 0.000000000000000000000000000000000000000000000000008478 185.0
WLSH3_k127_11394773_22 - - - - 0.00000000000000000000000000000000000000000004584 166.0
WLSH3_k127_11394773_23 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000003345 139.0
WLSH3_k127_11394773_24 Rubredoxin - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000001968 84.0
WLSH3_k127_11394773_3 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 1.743e-206 647.0
WLSH3_k127_11394773_4 PFAM beta-lactamase domain protein - - - 3.953e-197 621.0
WLSH3_k127_11394773_5 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 581.0
WLSH3_k127_11394773_6 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 515.0
WLSH3_k127_11394773_7 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 464.0
WLSH3_k127_11394773_8 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 462.0
WLSH3_k127_11394773_9 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 436.0
WLSH3_k127_11411566_0 Belongs to the glutamate synthase family - - - 2.384e-297 916.0
WLSH3_k127_11411566_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.789e-264 817.0
WLSH3_k127_11411566_2 PFAM glutamine amidotransferase, class-II - - - 3.845e-195 612.0
WLSH3_k127_11411566_3 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 497.0
WLSH3_k127_11411566_4 PFAM glutamate synthase alpha subunit domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 389.0
WLSH3_k127_11411566_5 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 285.0
WLSH3_k127_11424988_0 CHY zinc finger K16276 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0032446,GO:0036211,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0051603,GO:0061630,GO:0061659,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000004755 80.0
WLSH3_k127_11424988_1 Domain of unknown function (DU1801) - - - 0.000000000004607 66.0
WLSH3_k127_11433812_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 1.205e-262 815.0
WLSH3_k127_11433812_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.263e-254 789.0
WLSH3_k127_11433812_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000000004073 133.0
WLSH3_k127_11433812_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000000000004481 107.0
WLSH3_k127_11433812_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.828e-215 672.0
WLSH3_k127_11433812_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 594.0
WLSH3_k127_11433812_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 521.0
WLSH3_k127_11433812_5 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 500.0
WLSH3_k127_11433812_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 421.0
WLSH3_k127_11433812_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 385.0
WLSH3_k127_11433812_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000001006 228.0
WLSH3_k127_11433812_9 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000001486 192.0
WLSH3_k127_115480_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000217 291.0
WLSH3_k127_115480_1 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000000000000198 215.0
WLSH3_k127_115480_2 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000008071 189.0
WLSH3_k127_115480_3 - - - - 0.000000000000000000000000000003988 121.0
WLSH3_k127_115480_4 Ferredoxin K05337 - - 0.000000000000000002043 87.0
WLSH3_k127_115480_5 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07324,K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00002564 52.0
WLSH3_k127_11572626_0 PFAM formate nitrite transporter K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 464.0
WLSH3_k127_11572626_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 443.0
WLSH3_k127_11572626_2 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 320.0
WLSH3_k127_11572626_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.0000000000000000000000000000000000000000000000000004507 194.0
WLSH3_k127_11572626_4 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000006785 141.0
WLSH3_k127_11572626_5 - K06868 - 2.5.1.73 0.00000000000005198 73.0
WLSH3_k127_118285_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1392.0
WLSH3_k127_118285_1 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 614.0
WLSH3_k127_118285_10 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 399.0
WLSH3_k127_118285_11 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 374.0
WLSH3_k127_118285_12 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000005167 224.0
WLSH3_k127_118285_13 - - - - 0.0000000000000000000000000000000000000000000000002232 177.0
WLSH3_k127_118285_14 PDGLE domain K02009 - - 0.0000000000000000000000000000000000000000000000008017 176.0
WLSH3_k127_118285_15 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007,K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000001215 163.0
WLSH3_k127_118285_16 Belongs to the UPF0147 family K09721 - - 0.00000000000000001784 81.0
WLSH3_k127_118285_17 - - - - 0.0000000001332 65.0
WLSH3_k127_118285_18 - - - - 0.00000002458 59.0
WLSH3_k127_118285_19 - - - - 0.000001064 52.0
WLSH3_k127_118285_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 563.0
WLSH3_k127_118285_3 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 500.0
WLSH3_k127_118285_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 509.0
WLSH3_k127_118285_5 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 509.0
WLSH3_k127_118285_6 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 484.0
WLSH3_k127_118285_7 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 442.0
WLSH3_k127_118285_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 445.0
WLSH3_k127_118285_9 PFAM 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 406.0
WLSH3_k127_1217997_0 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 529.0
WLSH3_k127_1217997_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 420.0
WLSH3_k127_1217997_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 368.0
WLSH3_k127_1217997_3 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001767 271.0
WLSH3_k127_1217997_4 methanogenesis marker protein 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006113 269.0
WLSH3_k127_1217997_5 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000000000000000000000000684 226.0
WLSH3_k127_1296154_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.003e-215 674.0
WLSH3_k127_1296154_1 Domain of unknown function (DUF333) K14475 - - 0.000000000000000000009543 100.0
WLSH3_k127_1353544_0 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain K10947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 475.0
WLSH3_k127_1353544_1 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 422.0
WLSH3_k127_1353544_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000002878 94.0
WLSH3_k127_1353544_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000002612 64.0
WLSH3_k127_1402286_0 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 497.0
WLSH3_k127_1402286_1 Radical SAM ThiC family K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 374.0
WLSH3_k127_1402286_2 Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000002184 207.0
WLSH3_k127_1402286_3 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000002977 98.0
WLSH3_k127_1402286_4 HEAT repeats - - - 0.000000000001737 74.0
WLSH3_k127_1402286_5 TPR repeat - - - 0.00004968 51.0
WLSH3_k127_1415376_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1300.0
WLSH3_k127_1415376_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 529.0
WLSH3_k127_1415376_2 Mediates influx of magnesium ions K03284 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 470.0
WLSH3_k127_1415376_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 325.0
WLSH3_k127_1415376_4 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 300.0
WLSH3_k127_1415376_5 cation diffusion facilitator family transporter - - - 0.0000000000000001089 81.0
WLSH3_k127_1415376_6 Mechanosensitive ion channel K16052 - - 0.00008775 46.0
WLSH3_k127_147813_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000002997 168.0
WLSH3_k127_147813_1 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000001428 90.0
WLSH3_k127_149339_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 507.0
WLSH3_k127_149339_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000025 307.0
WLSH3_k127_149339_2 membrane-associated protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 288.0
WLSH3_k127_149339_3 - - - - 0.000000000000000000000000000000007993 138.0
WLSH3_k127_149339_4 - - - - 0.00000000000000002243 83.0
WLSH3_k127_1503245_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 1.274e-211 662.0
WLSH3_k127_1503245_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000009043 227.0
WLSH3_k127_1503245_2 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000003579 111.0
WLSH3_k127_1541801_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 590.0
WLSH3_k127_1541801_1 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 515.0
WLSH3_k127_1541801_2 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 408.0
WLSH3_k127_1541801_3 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 382.0
WLSH3_k127_1541801_4 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 381.0
WLSH3_k127_1541801_5 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 366.0
WLSH3_k127_1541801_6 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000002225 223.0
WLSH3_k127_1541801_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.00000000000000000000000000000000000000339 154.0
WLSH3_k127_1541801_8 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000000000000179 142.0
WLSH3_k127_1541801_9 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000000000000000001069 134.0
WLSH3_k127_1563082_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.883e-234 730.0
WLSH3_k127_1563082_1 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 322.0
WLSH3_k127_1563082_2 TIR domain - - - 0.0000000000000000000000000000000000001116 152.0
WLSH3_k127_1563082_3 - - - - 0.000000000000000000000006447 105.0
WLSH3_k127_1611846_0 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000001193 214.0
WLSH3_k127_1611846_1 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000116 206.0
WLSH3_k127_1611846_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000007152 94.0
WLSH3_k127_1611846_3 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000003966 71.0
WLSH3_k127_1674090_0 Uncharacterized membrane protein (DUF2298) - - - 2.899e-280 876.0
WLSH3_k127_1674090_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 6.836e-270 832.0
WLSH3_k127_1674090_10 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 466.0
WLSH3_k127_1674090_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 444.0
WLSH3_k127_1674090_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 380.0
WLSH3_k127_1674090_13 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 361.0
WLSH3_k127_1674090_14 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 329.0
WLSH3_k127_1674090_15 PFAM Glycosyl transferase family 2 K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 310.0
WLSH3_k127_1674090_16 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 294.0
WLSH3_k127_1674090_17 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001721 257.0
WLSH3_k127_1674090_18 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002853 257.0
WLSH3_k127_1674090_19 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001386 252.0
WLSH3_k127_1674090_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 2.99e-257 796.0
WLSH3_k127_1674090_20 Domain of unknown function (DUF3821) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001692 260.0
WLSH3_k127_1674090_21 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004717 235.0
WLSH3_k127_1674090_22 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000000000000000000000009284 219.0
WLSH3_k127_1674090_23 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000001152 206.0
WLSH3_k127_1674090_24 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000000000000004537 137.0
WLSH3_k127_1674090_25 - - - - 0.0000000000000000000000000000000002435 134.0
WLSH3_k127_1674090_26 Binds to the 23S rRNA K02896 - - 0.000000000000000000000000000003384 120.0
WLSH3_k127_1674090_27 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000001257 114.0
WLSH3_k127_1674090_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.234e-254 788.0
WLSH3_k127_1674090_4 PFAM glycosyl transferase family 39 - - - 1.84e-244 765.0
WLSH3_k127_1674090_5 Involved in cell shape control K22222 - - 1.436e-233 724.0
WLSH3_k127_1674090_6 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 4.851e-205 645.0
WLSH3_k127_1674090_7 PFAM amine oxidase - - - 4.196e-201 634.0
WLSH3_k127_1674090_8 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 492.0
WLSH3_k127_1674090_9 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 471.0
WLSH3_k127_1774286_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.317e-224 702.0
WLSH3_k127_1774286_1 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 2.461e-224 702.0
WLSH3_k127_1774286_10 UPF0391 membrane protein - - - 0.0000000000003798 70.0
WLSH3_k127_1774286_2 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 514.0
WLSH3_k127_1774286_3 Branched-chain amino acid transport system permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 484.0
WLSH3_k127_1774286_4 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005282 278.0
WLSH3_k127_1774286_5 PFAM Telomeric repeat-binding factor 2 - - - 0.0000000000000000000000000000000000000000000000000007839 191.0
WLSH3_k127_1774286_6 - - - - 0.000000000000000000000000662 108.0
WLSH3_k127_1774286_8 - - - - 0.00000000000000009318 83.0
WLSH3_k127_1774286_9 - - - - 0.0000000000000166 78.0
WLSH3_k127_177822_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 1.161e-217 679.0
WLSH3_k127_177822_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 535.0
WLSH3_k127_177822_2 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 361.0
WLSH3_k127_177822_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 325.0
WLSH3_k127_177822_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
WLSH3_k127_177822_5 - - - - 0.0000000001567 70.0
WLSH3_k127_1853416_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 1.902e-272 844.0
WLSH3_k127_1853416_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 1.865e-213 668.0
WLSH3_k127_1853416_10 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 385.0
WLSH3_k127_1853416_11 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 385.0
WLSH3_k127_1853416_12 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 372.0
WLSH3_k127_1853416_13 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 377.0
WLSH3_k127_1853416_14 PFAM TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 339.0
WLSH3_k127_1853416_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 315.0
WLSH3_k127_1853416_16 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 304.0
WLSH3_k127_1853416_17 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 285.0
WLSH3_k127_1853416_18 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
WLSH3_k127_1853416_19 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000000000000003907 188.0
WLSH3_k127_1853416_2 PFAM peptidase M50 - - - 1.831e-211 663.0
WLSH3_k127_1853416_20 metal-binding protein - - - 0.000000000000000000000000000000001604 131.0
WLSH3_k127_1853416_21 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000000001856 106.0
WLSH3_k127_1853416_22 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000001006 98.0
WLSH3_k127_1853416_23 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000000262 78.0
WLSH3_k127_1853416_3 PHP C-terminal domain protein - - - 7.551e-194 609.0
WLSH3_k127_1853416_4 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 592.0
WLSH3_k127_1853416_5 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 578.0
WLSH3_k127_1853416_6 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 509.0
WLSH3_k127_1853416_7 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 433.0
WLSH3_k127_1853416_8 Translation initiation factor 2 alpha subunit K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 423.0
WLSH3_k127_1853416_9 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 389.0
WLSH3_k127_1873654_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 289.0
WLSH3_k127_1873654_1 - - - - 0.000000000000000000000000000000000000000000000002968 177.0
WLSH3_k127_2096229_0 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 8.616e-234 732.0
WLSH3_k127_2096229_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 591.0
WLSH3_k127_2096229_2 PFAM glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 418.0
WLSH3_k127_2115033_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 479.0
WLSH3_k127_2115033_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 473.0
WLSH3_k127_2115033_2 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 419.0
WLSH3_k127_2115033_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 406.0
WLSH3_k127_2115033_4 CBS domain K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 337.0
WLSH3_k127_2115033_5 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 299.0
WLSH3_k127_2115033_6 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006165 276.0
WLSH3_k127_2115033_7 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002254 250.0
WLSH3_k127_2115033_8 Domain of unknown function DUF21 - - - 0.00001479 50.0
WLSH3_k127_2156297_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 355.0
WLSH3_k127_2156297_1 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 303.0
WLSH3_k127_2156297_10 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000007048 92.0
WLSH3_k127_2156297_11 protein conserved in archaea - - - 0.0007884 49.0
WLSH3_k127_2156297_2 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
WLSH3_k127_2156297_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 291.0
WLSH3_k127_2156297_4 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000000000000000000000000000000006304 179.0
WLSH3_k127_2156297_5 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000000000000000001996 168.0
WLSH3_k127_2156297_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000000000000000000000000009127 164.0
WLSH3_k127_2156297_7 CRS1_YhbY K07574 - - 0.00000000000000000000000000001577 119.0
WLSH3_k127_2156297_8 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000001351 106.0
WLSH3_k127_2156297_9 PFAM Ribosomal LX protein K02944 - - 0.00000000000000000000002857 106.0
WLSH3_k127_2186520_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1296.0
WLSH3_k127_2186520_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 8.14e-297 916.0
WLSH3_k127_2186520_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 409.0
WLSH3_k127_2186520_11 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 393.0
WLSH3_k127_2186520_12 PFAM major facilitator superfamily MFS_1 K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 389.0
WLSH3_k127_2186520_13 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 364.0
WLSH3_k127_2186520_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 336.0
WLSH3_k127_2186520_15 methyltransferase small K07579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 291.0
WLSH3_k127_2186520_16 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 287.0
WLSH3_k127_2186520_17 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000009975 249.0
WLSH3_k127_2186520_18 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000332 243.0
WLSH3_k127_2186520_19 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008874 254.0
WLSH3_k127_2186520_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 4.606e-285 884.0
WLSH3_k127_2186520_20 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000000000000000000000007404 173.0
WLSH3_k127_2186520_21 - - - - 0.0000000000000000000000000000000000000000004279 161.0
WLSH3_k127_2186520_22 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000881 158.0
WLSH3_k127_2186520_23 PFAM metallophosphoesterase - - - 0.0000000000000000000000000000000000000008199 162.0
WLSH3_k127_2186520_24 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 - - 0.0000000000000000000000000000000001142 140.0
WLSH3_k127_2186520_25 - - - - 0.00000000000000000000000000006053 118.0
WLSH3_k127_2186520_26 - - - - 0.00000000000000000000000001275 113.0
WLSH3_k127_2186520_27 - - - - 0.000000000000000000000006545 106.0
WLSH3_k127_2186520_28 PspC domain K03973 - - 0.00000000000000000005984 95.0
WLSH3_k127_2186520_29 - - - - 0.00000000000000000006254 101.0
WLSH3_k127_2186520_3 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 598.0
WLSH3_k127_2186520_30 - - - - 0.0000000000001284 72.0
WLSH3_k127_2186520_31 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 - - 0.00000001913 63.0
WLSH3_k127_2186520_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 540.0
WLSH3_k127_2186520_5 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 531.0
WLSH3_k127_2186520_6 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 520.0
WLSH3_k127_2186520_7 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 458.0
WLSH3_k127_2186520_8 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 459.0
WLSH3_k127_2186520_9 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 450.0
WLSH3_k127_2270998_0 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 328.0
WLSH3_k127_2270998_1 - K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 346.0
WLSH3_k127_2270998_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007459 263.0
WLSH3_k127_2270998_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000005822 174.0
WLSH3_k127_2270998_4 COG0681 Signal peptidase I K13280 - 3.4.21.89 0.0000000000000000000000008071 110.0
WLSH3_k127_2270998_5 Camelysin metallo-endopeptidase - - - 0.00000000000000000000001632 109.0
WLSH3_k127_2270998_8 Pfam Kelch - - - 0.00000002033 66.0
WLSH3_k127_2270998_9 PFAM von Willebrand factor type A - - - 0.000000273 58.0
WLSH3_k127_2288866_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1215.0
WLSH3_k127_2288866_1 Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor K00918 - 2.7.1.146,2.7.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 403.0
WLSH3_k127_2303386_0 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002293 252.0
WLSH3_k127_2303386_1 Uncharacterized protein conserved in archaea (DUF2121) - - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
WLSH3_k127_2303386_2 - - - - 0.00000000000000000000000000000000000000004094 161.0
WLSH3_k127_2303386_3 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.0000000000000000000000000000001036 131.0
WLSH3_k127_2336165_0 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 337.0
WLSH3_k127_2336165_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006621 314.0
WLSH3_k127_2336165_2 META domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 273.0
WLSH3_k127_2336165_3 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000029 190.0
WLSH3_k127_2336165_4 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000000000000000000000003585 134.0
WLSH3_k127_2336165_5 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000001381 97.0
WLSH3_k127_2336165_6 Dodecin K09165 - - 0.00000000001318 67.0
WLSH3_k127_2339981_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 422.0
WLSH3_k127_2339981_1 ATPases associated with a variety of cellular activities K02049,K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 285.0
WLSH3_k127_2339981_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
WLSH3_k127_2339981_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000007546 161.0
WLSH3_k127_2339981_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000008373 158.0
WLSH3_k127_2339981_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000003216 149.0
WLSH3_k127_2339981_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000001888 139.0
WLSH3_k127_2433640_0 Ferrous iron transport B domain protein K04759 - - 1.565e-229 727.0
WLSH3_k127_2433640_1 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 290.0
WLSH3_k127_2433640_2 Mn-dependent transcriptional regulator K03709 - - 0.000000000000000000000000000000000000004332 154.0
WLSH3_k127_2433640_3 Phage plasmid primase, P4 K06919 - - 0.000000000001597 68.0
WLSH3_k127_2498872_0 PAS domain K00974,K02485 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 389.0
WLSH3_k127_2498872_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000004074 129.0
WLSH3_k127_2498872_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000003915 135.0
WLSH3_k127_2498872_3 Pas domain - - - 0.000000000000000000000000005484 129.0
WLSH3_k127_2498872_4 PAS domain - - - 0.00000000000000002399 87.0
WLSH3_k127_2511828_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000007747 238.0
WLSH3_k127_2511828_1 Shikimate kinase K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000005831 229.0
WLSH3_k127_2511828_2 Protein of unknown function (DUF2769) - - - 0.000000000000000000002852 99.0
WLSH3_k127_2511828_3 Uncharacterized conserved protein (DUF2164) - - - 0.00000000000000000004723 91.0
WLSH3_k127_2511828_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000006585 78.0
WLSH3_k127_2511828_5 PFAM YcfA-like protein - - - 0.000000000003697 68.0
WLSH3_k127_2596802_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 510.0
WLSH3_k127_2596802_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001879 265.0
WLSH3_k127_2596802_2 Rhodanese Homology Domain - - - 0.000000000000000000002201 94.0
WLSH3_k127_2596802_3 - - - - 0.000000000000000005701 84.0
WLSH3_k127_2596802_4 cellular manganese ion homeostasis - - - 0.00001975 55.0
WLSH3_k127_2633976_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 1.39e-278 871.0
WLSH3_k127_2633976_1 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 4.196e-211 664.0
WLSH3_k127_2633976_2 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 6.04e-209 654.0
WLSH3_k127_2633976_3 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 392.0
WLSH3_k127_2633976_4 Domain of unknown function (DUF3821) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 331.0
WLSH3_k127_2633976_5 ATPase activity K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002596 277.0
WLSH3_k127_2633976_6 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000001626 219.0
WLSH3_k127_2633976_7 Thioredoxin - - - 0.00000000000000000000000000000000000000000001915 171.0
WLSH3_k127_2633976_8 Protein of unknown function (DUF2769) - - - 0.000000000000000000000008089 104.0
WLSH3_k127_2633976_9 - - - - 0.000000000000000001737 89.0
WLSH3_k127_2663032_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1508.0
WLSH3_k127_2663032_1 Anion transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 447.0
WLSH3_k127_2663032_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 439.0
WLSH3_k127_2663032_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 361.0
WLSH3_k127_2663032_4 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000004129 211.0
WLSH3_k127_2717021_0 Transport of potassium into the cell K03549 - - 4.999e-307 949.0
WLSH3_k127_2717021_1 PFAM Cation K03498 - - 8.4e-228 715.0
WLSH3_k127_2717021_2 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 381.0
WLSH3_k127_2717021_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000001021 148.0
WLSH3_k127_280906_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 458.0
WLSH3_k127_280906_1 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000001748 196.0
WLSH3_k127_280906_2 Domain of unknown function (DUF3821) - - - 0.0000000000000000000003015 106.0
WLSH3_k127_280906_4 - - - - 0.00001965 48.0
WLSH3_k127_2826027_0 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 514.0
WLSH3_k127_2826027_1 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 375.0
WLSH3_k127_2826027_2 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 297.0
WLSH3_k127_2826027_3 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007589 277.0
WLSH3_k127_2826027_4 PBS lyase HEAT-like repeat - - - 0.00000000000003743 79.0
WLSH3_k127_2836628_0 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000000000000000000002783 132.0
WLSH3_k127_2836628_1 - K00960 - 2.7.7.6 0.0000000000000000000000000001342 114.0
WLSH3_k127_2836628_2 Domain of unknown function (DUF333) K09712 - - 0.000000000000005552 86.0
WLSH3_k127_2836628_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000004351 64.0
WLSH3_k127_2839129_0 PFAM Glycosyl transferase family 2 - - - 0.0 2447.0
WLSH3_k127_2873028_0 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 294.0
WLSH3_k127_2873028_1 Prokaryotic RING finger family 2 - - - 0.00000000000000000000000000002366 120.0
WLSH3_k127_2873028_2 - - - - 0.000000000000000007963 83.0
WLSH3_k127_2994152_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1182.0
WLSH3_k127_2994152_1 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 518.0
WLSH3_k127_2994152_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 313.0
WLSH3_k127_3003847_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 4.159e-222 698.0
WLSH3_k127_3003847_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000001703 218.0
WLSH3_k127_3032813_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 8.67e-262 811.0
WLSH3_k127_3032813_1 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 1.893e-239 745.0
WLSH3_k127_3032813_10 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001509 258.0
WLSH3_k127_3032813_11 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003478 244.0
WLSH3_k127_3032813_12 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000004224 226.0
WLSH3_k127_3032813_13 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000006373 220.0
WLSH3_k127_3032813_14 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K14091,K15831 - - 0.000000000000000000000000000000000000000000000000001409 185.0
WLSH3_k127_3032813_15 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000000000000000000000000476 168.0
WLSH3_k127_3032813_16 Domain of unknown function DUF123 - - - 0.00000000000000000000000000000000000000007279 155.0
WLSH3_k127_3032813_17 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000008598 71.0
WLSH3_k127_3032813_2 PFAM aminotransferase class V - - - 1.308e-205 643.0
WLSH3_k127_3032813_3 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 585.0
WLSH3_k127_3032813_4 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 520.0
WLSH3_k127_3032813_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 381.0
WLSH3_k127_3032813_6 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 324.0
WLSH3_k127_3032813_7 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 311.0
WLSH3_k127_3032813_8 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 280.0
WLSH3_k127_3032813_9 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
WLSH3_k127_3038078_0 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005887 286.0
WLSH3_k127_3038078_1 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000000000000000000000000000009855 211.0
WLSH3_k127_3038078_2 Protein of unknown function (DUF2769) - - - 0.000000000000000003852 86.0
WLSH3_k127_3110348_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 1.362e-316 975.0
WLSH3_k127_3110348_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 8.4e-282 871.0
WLSH3_k127_3110348_2 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 361.0
WLSH3_k127_3110348_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004699 232.0
WLSH3_k127_3162113_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.95e-205 644.0
WLSH3_k127_3162113_1 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 302.0
WLSH3_k127_3162113_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 288.0
WLSH3_k127_3162113_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001346 229.0
WLSH3_k127_3162113_4 Protein of unknown function (DUF2769) - - - 0.000000000000000000000000000000000000005771 149.0
WLSH3_k127_3162113_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535 - 3.6.3.6 0.000000000000000000001377 96.0
WLSH3_k127_3202892_0 PFAM ABC transporter K00400 - - 5.036e-303 934.0
WLSH3_k127_3202892_1 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 490.0
WLSH3_k127_3202892_10 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000001649 144.0
WLSH3_k127_3202892_11 - - - - 0.0000000000000000000000000000000001373 136.0
WLSH3_k127_3202892_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000003627 125.0
WLSH3_k127_3202892_13 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000676 93.0
WLSH3_k127_3202892_15 Family of unknown function (DUF5320) - - - 0.0005723 46.0
WLSH3_k127_3202892_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 491.0
WLSH3_k127_3202892_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 431.0
WLSH3_k127_3202892_4 to Modification methylase in Methanococcus jannaschii (Q58392) and Methanobacterium thermoformicicum (P29568) K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 418.0
WLSH3_k127_3202892_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 283.0
WLSH3_k127_3202892_6 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000825 272.0
WLSH3_k127_3202892_7 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000004547 211.0
WLSH3_k127_3202892_8 - - - - 0.000000000000000000000000000000000000000000000000000501 188.0
WLSH3_k127_3202892_9 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000019 145.0
WLSH3_k127_3257106_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 1.846e-250 794.0
WLSH3_k127_3257106_1 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 1.453e-244 762.0
WLSH3_k127_3257106_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 530.0
WLSH3_k127_3257106_3 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 489.0
WLSH3_k127_3257106_4 PFAM oxidoreductase domain protein K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 413.0
WLSH3_k127_3257106_5 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006462 263.0
WLSH3_k127_3305196_0 Heat shock 70 kDa protein K04043 - - 0.0 1050.0
WLSH3_k127_3305196_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 571.0
WLSH3_k127_3305196_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000036 222.0
WLSH3_k127_3305196_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000133 119.0
WLSH3_k127_3305196_4 PBS lyase HEAT-like repeat - - - 0.0000000000000000001688 93.0
WLSH3_k127_3356929_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 593.0
WLSH3_k127_3356929_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 486.0
WLSH3_k127_3356929_2 methylase K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 405.0
WLSH3_k127_3356929_3 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 381.0
WLSH3_k127_3356929_4 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 334.0
WLSH3_k127_3356929_5 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 314.0
WLSH3_k127_3356929_6 membrane - - - 0.000000000000002508 77.0
WLSH3_k127_3381613_0 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 450.0
WLSH3_k127_3381613_1 Domain of unknown function (DU1801) - - - 0.0000000000000000000001513 104.0
WLSH3_k127_3381613_2 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000002154 102.0
WLSH3_k127_3381613_3 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000001162 96.0
WLSH3_k127_3381613_4 - - - - 0.000000000000003681 85.0
WLSH3_k127_3381613_5 - - - - 0.00009527 48.0
WLSH3_k127_3407242_0 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007025 259.0
WLSH3_k127_3407242_1 - - - - 0.000000000000000000000000000000000000003839 148.0
WLSH3_k127_3407242_2 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000002518 127.0
WLSH3_k127_3427807_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 489.0
WLSH3_k127_3427807_1 response regulator, receiver - - - 0.00000000000000000000000004914 108.0
WLSH3_k127_3465901_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1039.0
WLSH3_k127_3465901_1 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.0 1020.0
WLSH3_k127_3465901_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 466.0
WLSH3_k127_3465901_11 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 411.0
WLSH3_k127_3465901_12 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 339.0
WLSH3_k127_3465901_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 297.0
WLSH3_k127_3465901_14 Belongs to the UPF0305 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 293.0
WLSH3_k127_3465901_15 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 290.0
WLSH3_k127_3465901_16 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004943 253.0
WLSH3_k127_3465901_17 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000000000000000000000002656 215.0
WLSH3_k127_3465901_18 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000000000000000001175 192.0
WLSH3_k127_3465901_19 transcription activator, effector binding - - - 0.000000000000000000000000000000004074 129.0
WLSH3_k127_3465901_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 2.472e-241 755.0
WLSH3_k127_3465901_20 Protein of unknown function (DUF1294) - - - 0.000000000000000001179 89.0
WLSH3_k127_3465901_21 CDGSH-type zinc finger. Function unknown. - - - 0.000000000000000151 89.0
WLSH3_k127_3465901_23 Cupin - - - 0.0007219 46.0
WLSH3_k127_3465901_3 - - - - 1.032e-215 678.0
WLSH3_k127_3465901_4 - - - - 4.935e-197 618.0
WLSH3_k127_3465901_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K00619 - 2.3.1.1 7.499e-197 631.0
WLSH3_k127_3465901_6 PFAM Archaeal protein of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 602.0
WLSH3_k127_3465901_7 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 592.0
WLSH3_k127_3465901_8 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 525.0
WLSH3_k127_3465901_9 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 478.0
WLSH3_k127_3481714_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1106.0
WLSH3_k127_3481714_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0 1032.0
WLSH3_k127_3481714_10 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 289.0
WLSH3_k127_3481714_11 Belongs to the UPF0305 family K07012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 284.0
WLSH3_k127_3481714_12 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005792 283.0
WLSH3_k127_3481714_13 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000005876 232.0
WLSH3_k127_3481714_14 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000001197 216.0
WLSH3_k127_3481714_15 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000001415 200.0
WLSH3_k127_3481714_16 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000004093 188.0
WLSH3_k127_3481714_17 protein possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000000000000000000000917 164.0
WLSH3_k127_3481714_18 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.0000000000000000000000000000000007615 134.0
WLSH3_k127_3481714_19 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000001392 70.0
WLSH3_k127_3481714_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 1.074e-274 850.0
WLSH3_k127_3481714_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 3.796e-256 798.0
WLSH3_k127_3481714_4 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 8.687e-229 719.0
WLSH3_k127_3481714_5 PFAM amine oxidase - - - 1.315e-219 687.0
WLSH3_k127_3481714_6 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 493.0
WLSH3_k127_3481714_7 CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 468.0
WLSH3_k127_3481714_8 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 402.0
WLSH3_k127_3481714_9 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 342.0
WLSH3_k127_3536154_0 PFAM Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 401.0
WLSH3_k127_3536154_1 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006667 269.0
WLSH3_k127_3538605_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 345.0
WLSH3_k127_3538605_1 Rubrerythrin - - - 0.0000000000000000000000000000000000519 138.0
WLSH3_k127_3538605_2 - - - - 0.0000000000000000000000000009153 118.0
WLSH3_k127_3538605_3 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.0002123 47.0
WLSH3_k127_3539754_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 5.985e-209 651.0
WLSH3_k127_3539754_1 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 544.0
WLSH3_k127_3539754_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000635 228.0
WLSH3_k127_3539754_3 PFAM TPR repeat-containing protein - - - 0.00000000000000000000001601 106.0
WLSH3_k127_3550275_0 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 509.0
WLSH3_k127_3550275_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 385.0
WLSH3_k127_3550275_2 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000000000000000000002835 234.0
WLSH3_k127_3550275_3 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000000000000000000008011 178.0
WLSH3_k127_3550275_4 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000007644 83.0
WLSH3_k127_3554057_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005936 259.0
WLSH3_k127_3554057_1 Conserved region in glutamate synthase - - - 0.000000000000000000002695 93.0
WLSH3_k127_3570429_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000004202 204.0
WLSH3_k127_3570429_1 - - - - 0.0000000000000000000000000000000001154 138.0
WLSH3_k127_3690968_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000002798 175.0
WLSH3_k127_3690968_1 PFAM Yip1 domain - - - 0.0000000000000000000000000001709 125.0
WLSH3_k127_3691533_0 Thioesterase superfamily K10806 - - 0.000000000000000000000000000000000000000000000000000000000105 206.0
WLSH3_k127_3691533_1 - - - - 0.000000000000000000000000000000000000000000000000002761 196.0
WLSH3_k127_3752500_0 Anion transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 544.0
WLSH3_k127_3752500_1 PD-(D/E)XK nuclease superfamily K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000033 209.0
WLSH3_k127_3752500_2 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000306 179.0
WLSH3_k127_3752500_3 metal-binding protein - - - 0.000000000000000002917 87.0
WLSH3_k127_3752500_5 HEPN domain - - - 0.00000002066 61.0
WLSH3_k127_3759532_0 - K08963 - 5.3.1.23 1.485e-307 951.0
WLSH3_k127_3759532_1 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 348.0
WLSH3_k127_3759532_10 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000000000000000000000000000000000000254 214.0
WLSH3_k127_3759532_11 iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000005075 193.0
WLSH3_k127_3759532_12 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000001522 198.0
WLSH3_k127_3759532_13 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000084 188.0
WLSH3_k127_3759532_14 PFAM histidine triad (HIT) protein - - - 0.00000000000000000000000000000000000000000838 156.0
WLSH3_k127_3759532_15 Methyltransferase domain - - - 0.00000000000000000000000000000000608 137.0
WLSH3_k127_3759532_16 Protein of unknown function DUF134 - - - 0.0000000000000000000000000004825 115.0
WLSH3_k127_3759532_17 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.0000000000000000000015 98.0
WLSH3_k127_3759532_19 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.0000000001089 66.0
WLSH3_k127_3759532_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 327.0
WLSH3_k127_3759532_3 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 327.0
WLSH3_k127_3759532_4 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 320.0
WLSH3_k127_3759532_5 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 311.0
WLSH3_k127_3759532_6 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 314.0
WLSH3_k127_3759532_7 CGGC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 295.0
WLSH3_k127_3759532_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000007321 237.0
WLSH3_k127_3759532_9 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
WLSH3_k127_3782559_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 492.0
WLSH3_k127_3782559_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 359.0
WLSH3_k127_3782559_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 258.0
WLSH3_k127_3795046_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1693.0
WLSH3_k127_3795046_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.801e-240 745.0
WLSH3_k127_3795046_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 435.0
WLSH3_k127_3795046_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002155 231.0
WLSH3_k127_3822523_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 2164.0
WLSH3_k127_3822523_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1011.0
WLSH3_k127_3822523_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 475.0
WLSH3_k127_3822523_11 Threonine dehydratase K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 443.0
WLSH3_k127_3822523_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 342.0
WLSH3_k127_3822523_13 - K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002002 283.0
WLSH3_k127_3822523_14 transcription activator, effector binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003142 240.0
WLSH3_k127_3822523_15 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000004625 240.0
WLSH3_k127_3822523_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000583 226.0
WLSH3_k127_3822523_17 - - - - 0.000000000000000000000000000000000000000000000000000000001433 205.0
WLSH3_k127_3822523_18 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000858 184.0
WLSH3_k127_3822523_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.292e-261 810.0
WLSH3_k127_3822523_20 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000001664 139.0
WLSH3_k127_3822523_21 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000004522 135.0
WLSH3_k127_3822523_22 ATP synthase subunit C K02124 - - 0.000000000000000000000000000006378 119.0
WLSH3_k127_3822523_23 - - - - 0.0000000000000000000000000000938 121.0
WLSH3_k127_3822523_26 - - - - 0.0000000000001759 73.0
WLSH3_k127_3822523_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00001355 51.0
WLSH3_k127_3822523_3 V-type ATPase 116kDa subunit family K02123 - - 3.204e-248 781.0
WLSH3_k127_3822523_4 TIGRFAM UbiD family - - - 2.075e-215 674.0
WLSH3_k127_3822523_5 Protein of unknown function (DUF521) K09123 - - 4.604e-194 612.0
WLSH3_k127_3822523_6 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 597.0
WLSH3_k127_3822523_7 PBS lyase K22221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 587.0
WLSH3_k127_3822523_8 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 503.0
WLSH3_k127_3822523_9 Protein of unknown function (DUF1646) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 477.0
WLSH3_k127_3838214_0 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 567.0
WLSH3_k127_3838214_1 LVIVD repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 336.0
WLSH3_k127_3838214_2 PFAM ABC transporter K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001758 277.0
WLSH3_k127_3838214_3 PFAM ABC transporter K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001099 269.0
WLSH3_k127_3838214_4 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003259 245.0
WLSH3_k127_3838214_5 PFAM BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000000000000000002573 224.0
WLSH3_k127_4007630_0 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 486.0
WLSH3_k127_404052_0 Glycosyltransferase 28 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 476.0
WLSH3_k127_404052_1 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 414.0
WLSH3_k127_404052_2 cheY-homologous receiver domain K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 407.0
WLSH3_k127_404052_3 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 293.0
WLSH3_k127_404052_4 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000495 250.0
WLSH3_k127_4074583_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1069.0
WLSH3_k127_4074583_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000003442 218.0
WLSH3_k127_4091530_0 Belongs to the TPP enzyme family K00158 - 1.2.3.3 1.915e-279 868.0
WLSH3_k127_4091530_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 521.0
WLSH3_k127_4091530_2 archaeosine synthase activity K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 334.0
WLSH3_k127_4091530_3 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009152 276.0
WLSH3_k127_4091530_4 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002024 235.0
WLSH3_k127_4091530_5 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000008171 214.0
WLSH3_k127_4091530_6 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000005286 201.0
WLSH3_k127_4091530_7 Belongs to the glutamate synthase family - - - 0.00000002837 57.0
WLSH3_k127_4091530_8 protein related to deoxyribodipyrimidine photolyase K06876 - - 0.000006704 49.0
WLSH3_k127_4111306_0 TIGRFAM PAS sensor protein - - - 2.418e-226 757.0
WLSH3_k127_4111306_1 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 354.0
WLSH3_k127_4111306_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000009355 213.0
WLSH3_k127_4111306_3 KaiB K08481 - - 0.000000000000000000000000000000000000000000000001508 175.0
WLSH3_k127_4111306_4 KaiB K08481 - - 0.0000000000000000000000001677 106.0
WLSH3_k127_4159175_0 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 506.0
WLSH3_k127_4159175_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 391.0
WLSH3_k127_4159175_2 - - - - 0.0000000000002522 73.0
WLSH3_k127_418060_0 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 438.0
WLSH3_k127_418060_1 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 410.0
WLSH3_k127_418060_2 Radical SAM ThiC family K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001172 271.0
WLSH3_k127_418060_3 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000018 251.0
WLSH3_k127_418060_4 - - - - 0.000000000000000000000000000000000000000000000000000005288 191.0
WLSH3_k127_418060_5 - - - - 0.00000000000000001503 83.0
WLSH3_k127_418060_6 COG1413 FOG HEAT repeat K22221 - - 0.0000000000003486 77.0
WLSH3_k127_4231567_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 339.0
WLSH3_k127_4231567_1 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 311.0
WLSH3_k127_4231567_2 TIGRFAM N-acetyl sugar amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000001458 210.0
WLSH3_k127_4231567_3 - - - - 0.00000000000000000000000000000000000000001738 163.0
WLSH3_k127_4231567_4 TIGRFAM N-acetyl sugar amidotransferase - - - 0.00000000000000000000000000000000000000003542 154.0
WLSH3_k127_4231567_5 Phosphopantetheine attachment site - - - 0.0000000000000000000174 93.0
WLSH3_k127_4231567_6 - - - - 0.00000000000006507 74.0
WLSH3_k127_4231567_7 Evidence 4 Homologs of previously reported genes of - - - 0.000000172 63.0
WLSH3_k127_4235030_0 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 552.0
WLSH3_k127_4235030_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 462.0
WLSH3_k127_4235030_2 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 388.0
WLSH3_k127_4235030_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000001366 156.0
WLSH3_k127_450759_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 505.0
WLSH3_k127_450759_1 PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000002195 157.0
WLSH3_k127_450759_2 Trypsin-like peptidase domain - - - 0.0002626 45.0
WLSH3_k127_4517015_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.54e-229 713.0
WLSH3_k127_4517015_1 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 603.0
WLSH3_k127_4517015_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 361.0
WLSH3_k127_4517015_11 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002624 238.0
WLSH3_k127_4517015_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000005558 216.0
WLSH3_k127_4517015_13 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.000000000000000000000000000000000000000000000000000000000796 208.0
WLSH3_k127_4517015_14 Transcriptional regulator K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000003458 193.0
WLSH3_k127_4517015_15 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000000000000000000000002177 171.0
WLSH3_k127_4517015_16 4Fe-4S dicluster domain - - - 0.00000000000000000000000000201 113.0
WLSH3_k127_4517015_17 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000000000000000533 98.0
WLSH3_k127_4517015_18 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000003186 96.0
WLSH3_k127_4517015_19 - - - - 0.0000000001854 70.0
WLSH3_k127_4517015_2 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 537.0
WLSH3_k127_4517015_20 - - - - 0.000000009164 60.0
WLSH3_k127_4517015_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 527.0
WLSH3_k127_4517015_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 525.0
WLSH3_k127_4517015_5 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 494.0
WLSH3_k127_4517015_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 444.0
WLSH3_k127_4517015_7 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 428.0
WLSH3_k127_4517015_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 416.0
WLSH3_k127_4517015_9 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 363.0
WLSH3_k127_4582892_0 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000004299 104.0
WLSH3_k127_4582892_1 PFAM plasmid stabilization system - - - 0.00000000000000000009013 91.0
WLSH3_k127_4582892_3 - - - - 0.000003052 51.0
WLSH3_k127_4582892_4 Phage-associated protein - - - 0.000005505 56.0
WLSH3_k127_4588485_0 Uncharacterized protein conserved in archaea (DUF2114) - - - 2.354e-296 913.0
WLSH3_k127_4588485_1 PFAM Radical SAM domain protein K06937 - - 1.416e-270 837.0
WLSH3_k127_4588485_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008124 243.0
WLSH3_k127_4588485_11 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000000000002255 231.0
WLSH3_k127_4588485_12 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000006542 227.0
WLSH3_k127_4588485_13 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000000000000000000000001545 185.0
WLSH3_k127_4588485_14 Uncharacterised protein family UPF0058 - - - 0.000000000000000000000000000000000000000009834 154.0
WLSH3_k127_4588485_15 PFAM response regulator receiver - - - 0.000000000000000000000000000001817 136.0
WLSH3_k127_4588485_16 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000005242 120.0
WLSH3_k127_4588485_17 - - - - 0.00000000000000000000000000361 112.0
WLSH3_k127_4588485_18 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000001193 96.0
WLSH3_k127_4588485_19 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000001022 59.0
WLSH3_k127_4588485_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.688e-229 713.0
WLSH3_k127_4588485_20 Belongs to the P-Pant transferase superfamily K06133 - - 0.00003864 50.0
WLSH3_k127_4588485_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.625e-208 655.0
WLSH3_k127_4588485_4 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 3.026e-199 629.0
WLSH3_k127_4588485_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 521.0
WLSH3_k127_4588485_6 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000914 507.0
WLSH3_k127_4588485_7 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 489.0
WLSH3_k127_4588485_8 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 408.0
WLSH3_k127_4588485_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000775 293.0
WLSH3_k127_4593481_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.482e-218 682.0
WLSH3_k127_4593481_1 PFAM Aminotransferase class I and II K10907 - - 9.746e-207 648.0
WLSH3_k127_4593481_10 - - - - 0.000000000000000000000000000000000004796 138.0
WLSH3_k127_4593481_11 Molybdopterin converting factor, small subunit K03636 - - 0.0000000000000000000000000000000001803 133.0
WLSH3_k127_4593481_12 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000001395 113.0
WLSH3_k127_4593481_13 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000001264 78.0
WLSH3_k127_4593481_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 461.0
WLSH3_k127_4593481_3 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 396.0
WLSH3_k127_4593481_4 PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 371.0
WLSH3_k127_4593481_5 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 357.0
WLSH3_k127_4593481_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 349.0
WLSH3_k127_4593481_7 Molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000001182 221.0
WLSH3_k127_4593481_8 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000000005673 208.0
WLSH3_k127_4593481_9 Transcriptional regulator K07108 - - 0.00000000000000000000000000000000000000001139 155.0
WLSH3_k127_4599220_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1581.0
WLSH3_k127_4599220_1 PFAM CBS domain - - - 1.031e-274 850.0
WLSH3_k127_4599220_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000602 214.0
WLSH3_k127_4599220_11 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000000000005386 168.0
WLSH3_k127_4599220_12 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000007688 156.0
WLSH3_k127_4599220_13 zinc finger, SWIM - - - 0.00000000000000000000000000000000000000009487 153.0
WLSH3_k127_4599220_14 - - - - 0.0000000000000000000000000000000000005802 143.0
WLSH3_k127_4599220_15 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000473 117.0
WLSH3_k127_4599220_16 cation diffusion facilitator family transporter - - - 0.0000000000000000000003442 98.0
WLSH3_k127_4599220_17 - - - - 0.000000000000000000001114 96.0
WLSH3_k127_4599220_18 cation diffusion facilitator family transporter - - - 0.0000000000000003562 80.0
WLSH3_k127_4599220_19 cation diffusion facilitator family transporter - - - 0.000000000001094 68.0
WLSH3_k127_4599220_2 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 485.0
WLSH3_k127_4599220_20 cation diffusion facilitator family transporter - - - 0.00004346 49.0
WLSH3_k127_4599220_3 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 362.0
WLSH3_k127_4599220_4 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007821 327.0
WLSH3_k127_4599220_5 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 301.0
WLSH3_k127_4599220_6 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 291.0
WLSH3_k127_4599220_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 287.0
WLSH3_k127_4599220_8 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007572 272.0
WLSH3_k127_4599220_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002124 223.0
WLSH3_k127_4650813_0 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 348.0
WLSH3_k127_4650813_1 CGGC - - - 0.00000000000000000000000000000000000000000000000000000001208 199.0
WLSH3_k127_4650813_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - 0.0000000000000000000000000000006359 125.0
WLSH3_k127_4650813_3 Psort location Cytoplasmic, score - - - 0.0007178 45.0
WLSH3_k127_46624_0 Pfam:KaiC K08482 - - 4.51e-274 852.0
WLSH3_k127_46624_1 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 541.0
WLSH3_k127_46624_10 - - - - 0.00000000000000000000000000002888 128.0
WLSH3_k127_46624_12 - - - - 0.000000000000001844 83.0
WLSH3_k127_46624_13 UPF0391 membrane protein - - - 0.000000000001224 68.0
WLSH3_k127_46624_14 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000464 61.0
WLSH3_k127_46624_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 431.0
WLSH3_k127_46624_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 408.0
WLSH3_k127_46624_4 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 319.0
WLSH3_k127_46624_5 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002327 234.0
WLSH3_k127_46624_6 COG2226 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000375 236.0
WLSH3_k127_46624_7 - - - - 0.00000000000000000000000000000000001408 146.0
WLSH3_k127_46624_9 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000009201 131.0
WLSH3_k127_4706845_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 334.0
WLSH3_k127_4706845_1 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 0.0000000000000000000000000000000001407 132.0
WLSH3_k127_4706845_2 Domain of unknown function (DUF3821) - - - 0.00000001008 62.0
WLSH3_k127_4735137_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1234.0
WLSH3_k127_4735137_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0 1123.0
WLSH3_k127_4735137_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 460.0
WLSH3_k127_4735137_11 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 430.0
WLSH3_k127_4735137_12 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 415.0
WLSH3_k127_4735137_13 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 419.0
WLSH3_k127_4735137_14 transcription activator, effector binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 414.0
WLSH3_k127_4735137_15 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 410.0
WLSH3_k127_4735137_16 PFAM DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 383.0
WLSH3_k127_4735137_17 KH domain protein K06961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 335.0
WLSH3_k127_4735137_18 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 287.0
WLSH3_k127_4735137_19 PFAM NADH ubiquinone oxidoreductase, 20 K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001248 264.0
WLSH3_k127_4735137_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 9.814e-276 857.0
WLSH3_k127_4735137_20 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000645 234.0
WLSH3_k127_4735137_21 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000001206 209.0
WLSH3_k127_4735137_22 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000000000000000000000000000000000001248 165.0
WLSH3_k127_4735137_23 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.0000000000000000000000000000000000000000001383 163.0
WLSH3_k127_4735137_24 PFAM YHS domain - - - 0.0000000000000000000006317 96.0
WLSH3_k127_4735137_25 Trm112p-like protein - - - 0.000000000000000001286 86.0
WLSH3_k127_4735137_27 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000003777 75.0
WLSH3_k127_4735137_28 PFAM YHS domain - - - 0.0006215 44.0
WLSH3_k127_4735137_3 PFAM NADH Ubiquinone plastoquinone (complex I) K14086 - - 2.523e-272 850.0
WLSH3_k127_4735137_4 Involved in regulation of DNA replication K10725 - - 6.482e-258 797.0
WLSH3_k127_4735137_5 PFAM Aminotransferase class I and II K10907 - - 1.058e-206 647.0
WLSH3_k127_4735137_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 7.163e-206 643.0
WLSH3_k127_4735137_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 7.746e-199 622.0
WLSH3_k127_4735137_8 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 558.0
WLSH3_k127_4735137_9 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 536.0
WLSH3_k127_4748472_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1382.0
WLSH3_k127_4748472_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1154.0
WLSH3_k127_4748472_2 Helix-hairpin-helix domain K02347 - - 4.504e-205 653.0
WLSH3_k127_4748472_3 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 339.0
WLSH3_k127_4748472_4 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001814 278.0
WLSH3_k127_4753536_0 DEAD DEAH box helicase K06877 - - 0.0 1208.0
WLSH3_k127_4753536_1 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0 1082.0
WLSH3_k127_4753536_10 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 5.108e-220 687.0
WLSH3_k127_4753536_100 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000002977 110.0
WLSH3_k127_4753536_101 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000000000002972 99.0
WLSH3_k127_4753536_102 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000004644 96.0
WLSH3_k127_4753536_103 - - - - 0.00000000000000003491 87.0
WLSH3_k127_4753536_104 - - - - 0.000000156 60.0
WLSH3_k127_4753536_105 - - - - 0.0000002026 59.0
WLSH3_k127_4753536_11 PFAM dihydropteroate synthase, DHPS - - - 1.634e-214 676.0
WLSH3_k127_4753536_12 PFAM SufBD protein K07033 - - 3.394e-211 660.0
WLSH3_k127_4753536_13 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 2.42e-209 654.0
WLSH3_k127_4753536_14 AMP-binding enzyme - - - 6.157e-209 658.0
WLSH3_k127_4753536_15 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.529e-207 650.0
WLSH3_k127_4753536_16 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 1.209e-205 645.0
WLSH3_k127_4753536_17 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 3.239e-200 630.0
WLSH3_k127_4753536_18 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 1.343e-199 625.0
WLSH3_k127_4753536_19 Belongs to the peptidase M24B family - - - 1.958e-199 628.0
WLSH3_k127_4753536_2 PFAM chaperonin Cpn60 TCP-1 K22447 - - 5.611e-315 969.0
WLSH3_k127_4753536_20 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 7.677e-196 617.0
WLSH3_k127_4753536_21 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 600.0
WLSH3_k127_4753536_22 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 590.0
WLSH3_k127_4753536_23 Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 595.0
WLSH3_k127_4753536_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 564.0
WLSH3_k127_4753536_25 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 550.0
WLSH3_k127_4753536_26 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 551.0
WLSH3_k127_4753536_27 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 537.0
WLSH3_k127_4753536_28 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 528.0
WLSH3_k127_4753536_29 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 526.0
WLSH3_k127_4753536_3 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 6.664e-290 896.0
WLSH3_k127_4753536_30 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 516.0
WLSH3_k127_4753536_31 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 497.0
WLSH3_k127_4753536_32 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 496.0
WLSH3_k127_4753536_33 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 494.0
WLSH3_k127_4753536_34 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 483.0
WLSH3_k127_4753536_35 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 492.0
WLSH3_k127_4753536_36 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 477.0
WLSH3_k127_4753536_37 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 475.0
WLSH3_k127_4753536_38 Cysteine-rich small domain K08260 - 3.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 422.0
WLSH3_k127_4753536_39 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 409.0
WLSH3_k127_4753536_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 5.049e-285 884.0
WLSH3_k127_4753536_40 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 400.0
WLSH3_k127_4753536_41 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 395.0
WLSH3_k127_4753536_42 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 375.0
WLSH3_k127_4753536_43 Type I restriction-modification system methyltransferase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 402.0
WLSH3_k127_4753536_44 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 376.0
WLSH3_k127_4753536_45 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 373.0
WLSH3_k127_4753536_46 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 362.0
WLSH3_k127_4753536_47 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 364.0
WLSH3_k127_4753536_48 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 360.0
WLSH3_k127_4753536_49 Domain of unknown function (DUF1917) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008256 355.0
WLSH3_k127_4753536_5 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.148e-277 863.0
WLSH3_k127_4753536_50 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 355.0
WLSH3_k127_4753536_51 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 327.0
WLSH3_k127_4753536_52 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 329.0
WLSH3_k127_4753536_53 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 311.0
WLSH3_k127_4753536_54 transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
WLSH3_k127_4753536_55 sugar phosphatases of the HAD superfamily K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 306.0
WLSH3_k127_4753536_56 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 291.0
WLSH3_k127_4753536_57 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 291.0
WLSH3_k127_4753536_58 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 291.0
WLSH3_k127_4753536_59 Exonuclease K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 297.0
WLSH3_k127_4753536_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 2.303e-264 821.0
WLSH3_k127_4753536_60 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009532 286.0
WLSH3_k127_4753536_61 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000003873 258.0
WLSH3_k127_4753536_62 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003221 259.0
WLSH3_k127_4753536_63 toxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005592 255.0
WLSH3_k127_4753536_64 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000541 234.0
WLSH3_k127_4753536_65 PFAM cyclase family protein K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001136 240.0
WLSH3_k127_4753536_66 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000001528 237.0
WLSH3_k127_4753536_67 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008763 235.0
WLSH3_k127_4753536_68 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000001973 232.0
WLSH3_k127_4753536_69 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
WLSH3_k127_4753536_7 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 1.178e-239 743.0
WLSH3_k127_4753536_70 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000001042 223.0
WLSH3_k127_4753536_71 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000000000000000000000009401 217.0
WLSH3_k127_4753536_72 - - - - 0.00000000000000000000000000000000000000000000000000000000003575 207.0
WLSH3_k127_4753536_73 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000000000000000000000000000000000272 199.0
WLSH3_k127_4753536_74 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000004432 198.0
WLSH3_k127_4753536_75 - - - - 0.00000000000000000000000000000000000000000000000000000452 196.0
WLSH3_k127_4753536_76 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000000000000000000000000000000000000002033 186.0
WLSH3_k127_4753536_77 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000004451 181.0
WLSH3_k127_4753536_78 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000001205 175.0
WLSH3_k127_4753536_79 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.000000000000000000000000000000000000000000000005149 174.0
WLSH3_k127_4753536_8 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 1.225e-231 722.0
WLSH3_k127_4753536_80 - - - - 0.00000000000000000000000000000000000000000000001715 176.0
WLSH3_k127_4753536_81 - - - - 0.00000000000000000000000000000000000000000000003149 183.0
WLSH3_k127_4753536_82 metal-dependent phosphoesterases (PHP family) - - - 0.0000000000000000000000000000000000000000000005448 174.0
WLSH3_k127_4753536_83 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000009207 171.0
WLSH3_k127_4753536_84 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000007733 166.0
WLSH3_k127_4753536_85 PFAM Transglutaminase-like - - - 0.00000000000000000000000000000000000000000006424 168.0
WLSH3_k127_4753536_86 - - - - 0.00000000000000000000000000000000000000000615 157.0
WLSH3_k127_4753536_87 - - - - 0.00000000000000000000000000000000000000001365 157.0
WLSH3_k127_4753536_88 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171,K00188 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000001177 151.0
WLSH3_k127_4753536_89 Large family of predicted nucleotide-binding domains K07158 - - 0.0000000000000000000000000000000000000001224 155.0
WLSH3_k127_4753536_9 PFAM Thiolase K00626 - 2.3.1.9 5.628e-223 694.0
WLSH3_k127_4753536_90 - - - - 0.000000000000000000000000000000000000001354 147.0
WLSH3_k127_4753536_91 - K00960 - 2.7.7.6 0.0000000000000000000000000000000000006298 138.0
WLSH3_k127_4753536_92 Pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000003596 140.0
WLSH3_k127_4753536_93 - - - - 0.00000000000000000000000000000000009428 135.0
WLSH3_k127_4753536_94 SpoVT / AbrB like domain - - - 0.0000000000000000000000000000000004314 132.0
WLSH3_k127_4753536_95 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.000000000000000000000000000000005761 130.0
WLSH3_k127_4753536_96 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000000000000001314 116.0
WLSH3_k127_4753536_97 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000001503 122.0
WLSH3_k127_4753536_98 - - - - 0.0000000000000000000000000009823 121.0
WLSH3_k127_4753536_99 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000000000001092 111.0
WLSH3_k127_4766131_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.714e-276 855.0
WLSH3_k127_4766131_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 497.0
WLSH3_k127_4766131_2 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 334.0
WLSH3_k127_4766131_3 Integral membrane protein DUF106 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 306.0
WLSH3_k127_4766131_4 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 304.0
WLSH3_k127_4766131_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 295.0
WLSH3_k127_4766131_6 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002569 248.0
WLSH3_k127_4766131_7 amino acid K16263 - - 0.000000000000000000000000000000000000000000000000000004213 201.0
WLSH3_k127_4766131_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000002353 191.0
WLSH3_k127_4766131_9 binds to the 23S rRNA K02876 - - 0.00000005275 54.0
WLSH3_k127_4823881_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 7.255e-255 789.0
WLSH3_k127_4823881_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 8.251e-224 698.0
WLSH3_k127_4823881_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 516.0
WLSH3_k127_4823881_3 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 345.0
WLSH3_k127_4823881_4 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 333.0
WLSH3_k127_4823881_5 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000000000000000000001619 266.0
WLSH3_k127_4823881_6 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000000000000000000000000009566 233.0
WLSH3_k127_4823881_7 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000006568 189.0
WLSH3_k127_4823881_8 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000000001407 180.0
WLSH3_k127_4890812_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 8.9e-308 953.0
WLSH3_k127_4890812_1 Oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004722 276.0
WLSH3_k127_4890812_2 transcriptional K07729 - - 0.0000000000000000000001394 99.0
WLSH3_k127_4890812_3 Parallel beta-helix repeats - - - 0.00000000000000000007748 95.0
WLSH3_k127_4890812_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000002401 80.0
WLSH3_k127_4890812_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000001452 61.0
WLSH3_k127_4890812_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000004239 52.0
WLSH3_k127_4890826_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0 1062.0
WLSH3_k127_4890826_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.187e-291 902.0
WLSH3_k127_4890826_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 577.0
WLSH3_k127_4890826_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 569.0
WLSH3_k127_4890826_4 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 496.0
WLSH3_k127_4890826_5 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 399.0
WLSH3_k127_4890826_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 364.0
WLSH3_k127_4890826_7 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007,K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000001658 157.0
WLSH3_k127_4890826_8 - - - - 0.000000000000000001073 94.0
WLSH3_k127_4919666_0 CBS domain containing protein - - - 5.438e-212 664.0
WLSH3_k127_4919666_1 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 596.0
WLSH3_k127_4919666_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 379.0
WLSH3_k127_4919666_3 archaeal Zn-finger protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 320.0
WLSH3_k127_4919666_4 Domain of unknown function (DUF371) K09738 - - 0.0000000000000000000000000000000000000000000000000000000000000000004751 230.0
WLSH3_k127_4919666_5 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000007167 105.0
WLSH3_k127_4919666_6 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.000000000001678 69.0
WLSH3_k127_4919666_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0008007 44.0
WLSH3_k127_49623_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 2.73e-309 954.0
WLSH3_k127_49623_1 ATPase family associated with various cellular activities (AAA) - - - 1.97e-271 841.0
WLSH3_k127_49623_10 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 586.0
WLSH3_k127_49623_11 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 541.0
WLSH3_k127_49623_12 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 520.0
WLSH3_k127_49623_13 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 510.0
WLSH3_k127_49623_14 Belongs to the UPF0285 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 450.0
WLSH3_k127_49623_15 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 375.0
WLSH3_k127_49623_16 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 361.0
WLSH3_k127_49623_17 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 306.0
WLSH3_k127_49623_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 287.0
WLSH3_k127_49623_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 8.525e-260 806.0
WLSH3_k127_49623_20 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04068 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000004942 215.0
WLSH3_k127_49623_21 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000003418 196.0
WLSH3_k127_49623_22 - - - - 0.00000000000000000000000000000000000000000000000000009094 189.0
WLSH3_k127_49623_24 lycopene cyclase - - - 0.00000000000000000000000000000000000000000000002089 179.0
WLSH3_k127_49623_25 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000136 160.0
WLSH3_k127_49623_26 - - - - 0.00000000000000000000000000000000008774 138.0
WLSH3_k127_49623_27 - - - - 0.00000005064 59.0
WLSH3_k127_49623_3 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 1.022e-240 750.0
WLSH3_k127_49623_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.356e-229 715.0
WLSH3_k127_49623_5 SMART Elongator protein 3 MiaB NifB - - - 1.972e-211 665.0
WLSH3_k127_49623_6 FAD dependent oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 5.775e-210 662.0
WLSH3_k127_49623_7 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 1.183e-209 655.0
WLSH3_k127_49623_8 phosphoglycerate mutase K15635 - 5.4.2.12 1.331e-196 617.0
WLSH3_k127_49623_9 PFAM Radical SAM domain protein K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 579.0
WLSH3_k127_4981556_0 SMART Elongator protein 3 MiaB NifB K22226 - - 1.056e-215 674.0
WLSH3_k127_4981556_1 Pas domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 525.0
WLSH3_k127_4981556_2 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000506 250.0
WLSH3_k127_4981556_3 SMART regulatory protein AsnC Lrp family K22225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003644 241.0
WLSH3_k127_4981556_4 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000000000000000000000006846 169.0
WLSH3_k127_4981556_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000004207 49.0
WLSH3_k127_5041016_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 330.0
WLSH3_k127_5041016_1 DeoC/LacD family aldolase - - - 0.0000000000000000000000000000000000000000000000000007002 193.0
WLSH3_k127_5041016_2 PFAM Yip1 domain - - - 0.00000000000000000000000002583 116.0
WLSH3_k127_5041016_3 GYD domain - - - 0.00000000000000000000000101 106.0
WLSH3_k127_5041016_6 - - - - 0.00000000001688 68.0
WLSH3_k127_5041016_7 - - - - 0.0001479 46.0
WLSH3_k127_5122423_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 384.0
WLSH3_k127_5122423_1 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 315.0
WLSH3_k127_5122423_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002421 278.0
WLSH3_k127_5122423_3 Small multi-drug export protein - - - 0.000000000000000000000000000000000000000000009181 174.0
WLSH3_k127_5122423_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07324,K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000000000000002069 152.0
WLSH3_k127_5122423_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000002527 149.0
WLSH3_k127_5122423_6 - - - - 0.00000006912 61.0
WLSH3_k127_5154097_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.017e-230 721.0
WLSH3_k127_5154097_1 PFAM glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000002076 200.0
WLSH3_k127_5154097_2 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000007587 125.0
WLSH3_k127_5172750_0 COG0590 Cytosine adenosine deaminases K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000001079 243.0
WLSH3_k127_5172750_1 Flavodoxin K03839 - - 0.0000000000000000000000000000000001364 139.0
WLSH3_k127_5172750_2 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000001096 130.0
WLSH3_k127_5172750_3 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000004619 127.0
WLSH3_k127_5212730_0 COG0590 Cytosine adenosine deaminases K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
WLSH3_k127_5212730_1 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000000000000000000000000000000007969 206.0
WLSH3_k127_5212730_2 PFAM methyltransferase - - - 0.000000000000199 74.0
WLSH3_k127_5273482_0 associated with various cellular activities K03695,K03696 - - 0.0 1448.0
WLSH3_k127_5273482_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.794e-235 730.0
WLSH3_k127_5273482_10 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000001043 154.0
WLSH3_k127_5273482_11 - - - - 0.0000002204 58.0
WLSH3_k127_5273482_2 Involved in regulation of DNA replication K10725 - - 2.262e-212 662.0
WLSH3_k127_5273482_3 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 580.0
WLSH3_k127_5273482_4 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 503.0
WLSH3_k127_5273482_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 328.0
WLSH3_k127_5273482_6 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004871 279.0
WLSH3_k127_5273482_7 RuvA, C-terminal domain K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002221 246.0
WLSH3_k127_5273482_8 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000004602 220.0
WLSH3_k127_5273482_9 - - - - 0.000000000000000000000000000000000000000000000000000002496 198.0
WLSH3_k127_5274765_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0 1030.0
WLSH3_k127_5274765_1 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 479.0
WLSH3_k127_5274765_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 320.0
WLSH3_k127_5274765_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004171 241.0
WLSH3_k127_532424_0 in RNase L inhibitor, RLI K06174 - - 0.0 1060.0
WLSH3_k127_532424_1 SMART PAS domain containing protein K03406 - - 0.0 1028.0
WLSH3_k127_532424_10 TPR repeat - - - 0.00000000000000000000000000000000000000000000000001099 185.0
WLSH3_k127_532424_11 RNase L inhibitor, RLI - - - 0.0000000000000000000000000000000000000000000000004904 177.0
WLSH3_k127_532424_12 - - - - 0.0000000000000000000000000000000000000000000001173 177.0
WLSH3_k127_532424_13 - - - - 0.000000000000000000000001288 104.0
WLSH3_k127_532424_14 - - - - 0.0000000000000000000001358 98.0
WLSH3_k127_532424_15 - - - - 0.0000000000000000000003579 96.0
WLSH3_k127_532424_2 SMART PAS domain containing protein K03406 - - 4.781e-272 852.0
WLSH3_k127_532424_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 522.0
WLSH3_k127_532424_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 514.0
WLSH3_k127_532424_5 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 430.0
WLSH3_k127_532424_6 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 314.0
WLSH3_k127_532424_7 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000008859 263.0
WLSH3_k127_532424_8 CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004843 260.0
WLSH3_k127_532424_9 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000114 227.0
WLSH3_k127_5380440_0 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.000000000000000000000000000000002188 134.0
WLSH3_k127_5380440_1 Methyltransferase type 11 - - - 0.0000000004807 61.0
WLSH3_k127_542235_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 432.0
WLSH3_k127_542235_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 432.0
WLSH3_k127_5424976_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001895 280.0
WLSH3_k127_5424976_1 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000002304 209.0
WLSH3_k127_5424976_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000006302 176.0
WLSH3_k127_5424976_3 - - - - 0.000000000001611 74.0
WLSH3_k127_5447299_0 Collagenase K08303 - - 2.835e-261 831.0
WLSH3_k127_5447299_1 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 501.0
WLSH3_k127_5447299_2 PFAM glutamate--cysteine ligase, GCS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 377.0
WLSH3_k127_5447299_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 362.0
WLSH3_k127_5447299_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 340.0
WLSH3_k127_5447299_5 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004422 284.0
WLSH3_k127_5447299_6 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000000000000000000000000001191 196.0
WLSH3_k127_5447299_7 small multi-drug export - - - 0.0000000000000000000000000001152 123.0
WLSH3_k127_5447299_8 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000008931 52.0
WLSH3_k127_5531348_0 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 1.183e-288 892.0
WLSH3_k127_5531348_1 PFAM ribonuclease II K01147 - 3.1.13.1 2.487e-219 690.0
WLSH3_k127_5531348_10 Heat shock 70 kDa protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 353.0
WLSH3_k127_5531348_11 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 324.0
WLSH3_k127_5531348_12 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 319.0
WLSH3_k127_5531348_13 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000035 236.0
WLSH3_k127_5531348_14 related to archaeal Holliday junction resolvase - - - 0.00000000000000000000000000000000000000000000000000001905 193.0
WLSH3_k127_5531348_15 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000004358 188.0
WLSH3_k127_5531348_16 - - - - 0.0000000000000000000000000000000000000000000000002255 181.0
WLSH3_k127_5531348_17 TIR domain - - - 0.00000000000000000000000000000000000000000000002737 177.0
WLSH3_k127_5531348_19 - K00960 - 2.7.7.6 0.00000000000000000000000000000008519 126.0
WLSH3_k127_5531348_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 434.0
WLSH3_k127_5531348_20 transcription activator, effector binding - - - 0.000000000000000000000009563 104.0
WLSH3_k127_5531348_3 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 427.0
WLSH3_k127_5531348_4 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 371.0
WLSH3_k127_5531348_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 371.0
WLSH3_k127_5531348_6 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 369.0
WLSH3_k127_5531348_7 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
WLSH3_k127_5531348_8 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 364.0
WLSH3_k127_5531348_9 TIGRFAM MIP family channel K02440,K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 356.0
WLSH3_k127_5592084_0 TIGRFAM acetate--CoA ligase K01895 - 6.2.1.1 0.0 1137.0
WLSH3_k127_5592084_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.324e-277 855.0
WLSH3_k127_5592084_10 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 315.0
WLSH3_k127_5592084_11 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 285.0
WLSH3_k127_5592084_12 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001727 229.0
WLSH3_k127_5592084_13 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000001503 194.0
WLSH3_k127_5592084_14 Zinc-ribbon containing domain - - - 0.00000000000000000000000000000000000000005348 151.0
WLSH3_k127_5592084_15 - - - - 0.00000000000000000000000000000000338 132.0
WLSH3_k127_5592084_16 cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000008412 132.0
WLSH3_k127_5592084_17 chorismate mutase K04093 - 5.4.99.5 0.000000000000000000000000000001145 123.0
WLSH3_k127_5592084_18 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000007193 83.0
WLSH3_k127_5592084_19 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.0000000000000000161 82.0
WLSH3_k127_5592084_2 COG0477 Permeases of the major facilitator superfamily K08177 - - 5.582e-210 659.0
WLSH3_k127_5592084_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 1.579e-195 616.0
WLSH3_k127_5592084_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 592.0
WLSH3_k127_5592084_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 505.0
WLSH3_k127_5592084_6 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 502.0
WLSH3_k127_5592084_7 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 474.0
WLSH3_k127_5592084_8 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 338.0
WLSH3_k127_5592084_9 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 316.0
WLSH3_k127_5596119_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000001701 186.0
WLSH3_k127_5596119_1 glucosylceramidase activity - - - 0.0000000000000000000000000000000001801 135.0
WLSH3_k127_5596119_2 Belongs to the UPF0248 family K09715 - - 0.00000000000001839 74.0
WLSH3_k127_5596119_3 Protein of unknown function (DUF2877) - - - 0.0000000003595 71.0
WLSH3_k127_5656676_1 - - - - 0.00000000000479 67.0
WLSH3_k127_576990_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 7.364e-256 800.0
WLSH3_k127_576990_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 318.0
WLSH3_k127_5813202_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 2.162e-201 628.0
WLSH3_k127_5813202_1 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 595.0
WLSH3_k127_5813202_2 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 535.0
WLSH3_k127_5813202_3 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 504.0
WLSH3_k127_5813202_4 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 424.0
WLSH3_k127_5813202_5 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 411.0
WLSH3_k127_5813202_6 PFAM sigma-70 region 4 domain protein K09714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 252.0
WLSH3_k127_5813202_7 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000002203 222.0
WLSH3_k127_5815116_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 5.279e-233 727.0
WLSH3_k127_5815116_1 LOR SDH bifunctional enzyme conserved - - - 2.096e-221 691.0
WLSH3_k127_5815116_10 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000824 227.0
WLSH3_k127_5815116_11 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000000000000007892 184.0
WLSH3_k127_5815116_12 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000000000000000000001826 186.0
WLSH3_k127_5815116_13 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000000000000009601 139.0
WLSH3_k127_5815116_2 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 608.0
WLSH3_k127_5815116_3 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 606.0
WLSH3_k127_5815116_4 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 584.0
WLSH3_k127_5815116_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 526.0
WLSH3_k127_5815116_6 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 518.0
WLSH3_k127_5815116_7 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 484.0
WLSH3_k127_5815116_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 379.0
WLSH3_k127_5815116_9 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 355.0
WLSH3_k127_5867499_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 9.847e-228 710.0
WLSH3_k127_5867499_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 1.435e-209 657.0
WLSH3_k127_5867499_10 TIGRFAM formate dehydrogenase family accessory protein FdhD K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000155 250.0
WLSH3_k127_5867499_11 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000295 248.0
WLSH3_k127_5867499_12 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000003934 230.0
WLSH3_k127_5867499_13 TIGRFAM phosphohistidine phosphatase SixA K08296 - - 0.000000000000000000000000000000000000000000000000004321 186.0
WLSH3_k127_5867499_14 response regulator, receiver K03413,K07662,K07667 - - 0.000000000000000000000000000000000000000000000005449 175.0
WLSH3_k127_5867499_15 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000000000006368 146.0
WLSH3_k127_5867499_16 TfuA-like protein - - - 0.0000000000000000000000000000000000001041 145.0
WLSH3_k127_5867499_17 - - - - 0.0000000000000000000000000000000000007617 141.0
WLSH3_k127_5867499_18 - - - - 0.000000000000000000000000000000114 131.0
WLSH3_k127_5867499_19 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000004061 125.0
WLSH3_k127_5867499_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 1.541e-202 636.0
WLSH3_k127_5867499_20 transcription factor (CBF NF-Y) - - - 0.00000000000000000000000002192 109.0
WLSH3_k127_5867499_21 PFAM Uncharacterised conserved protein UCP006577 - - - 0.000000000000000000503 89.0
WLSH3_k127_5867499_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 603.0
WLSH3_k127_5867499_4 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 578.0
WLSH3_k127_5867499_5 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 549.0
WLSH3_k127_5867499_6 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 513.0
WLSH3_k127_5867499_7 signal transduction protein with CBS domains K07744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 468.0
WLSH3_k127_5867499_8 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 435.0
WLSH3_k127_5867499_9 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 252.0
WLSH3_k127_5894667_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 336.0
WLSH3_k127_5894667_1 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000002981 211.0
WLSH3_k127_5894667_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000000366 174.0
WLSH3_k127_5907267_0 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000004767 202.0
WLSH3_k127_5907267_1 - - - - 0.00000000000000000000000000000000000000001411 163.0
WLSH3_k127_5907267_2 - - - - 0.000601 43.0
WLSH3_k127_5933685_0 Amidinotransferase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 528.0
WLSH3_k127_5933685_1 Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 431.0
WLSH3_k127_5933685_2 MULE transposase domain - - - 0.0000000005974 62.0
WLSH3_k127_5934209_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1069.0
WLSH3_k127_5934209_1 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 3.45e-287 889.0
WLSH3_k127_5934209_10 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 5.331e-234 730.0
WLSH3_k127_5934209_11 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 559.0
WLSH3_k127_5934209_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 512.0
WLSH3_k127_5934209_13 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 468.0
WLSH3_k127_5934209_14 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 457.0
WLSH3_k127_5934209_15 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 460.0
WLSH3_k127_5934209_16 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 411.0
WLSH3_k127_5934209_17 O-methyltransferase K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 338.0
WLSH3_k127_5934209_18 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 335.0
WLSH3_k127_5934209_19 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 328.0
WLSH3_k127_5934209_2 Belongs to the TCP-1 chaperonin family K22447 - - 1.316e-285 884.0
WLSH3_k127_5934209_20 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 286.0
WLSH3_k127_5934209_21 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000755 277.0
WLSH3_k127_5934209_22 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001229 263.0
WLSH3_k127_5934209_23 ZPR1-related zinc finger protein K06874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001712 248.0
WLSH3_k127_5934209_24 Pfam:DUF552 K09152 - - 0.00000000000000000000000000000000000000000000000000000000000000002036 224.0
WLSH3_k127_5934209_25 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000003285 233.0
WLSH3_k127_5934209_26 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000000000000000000000000000000000000003677 220.0
WLSH3_k127_5934209_27 - - - - 0.000000000000000000000000000000000000000000000000000004437 194.0
WLSH3_k127_5934209_28 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000001616 190.0
WLSH3_k127_5934209_29 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000001063 165.0
WLSH3_k127_5934209_3 DEAD DEAH box helicase K03724 - - 5.145e-276 867.0
WLSH3_k127_5934209_30 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000000000000002494 151.0
WLSH3_k127_5934209_31 binds to the 23S rRNA K02922 - - 0.000000000000000000000000000001417 120.0
WLSH3_k127_5934209_32 SigmaK-factor processing regulatory protein BofA K06317 - - 0.00000000000000000000000000005184 117.0
WLSH3_k127_5934209_33 - - - - 0.00000000000000000000000003467 107.0
WLSH3_k127_5934209_34 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000000009562 108.0
WLSH3_k127_5934209_35 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000002012 101.0
WLSH3_k127_5934209_37 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000004157 95.0
WLSH3_k127_5934209_38 - - - - 0.0002999 44.0
WLSH3_k127_5934209_4 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.284e-268 842.0
WLSH3_k127_5934209_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.324e-268 828.0
WLSH3_k127_5934209_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.593e-259 808.0
WLSH3_k127_5934209_7 Filamentation induced by cAMP protein fic - - - 2.908e-256 795.0
WLSH3_k127_5934209_8 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 9.893e-252 784.0
WLSH3_k127_5934209_9 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 6.845e-240 751.0
WLSH3_k127_5944873_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1202.0
WLSH3_k127_5944873_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.0 1069.0
WLSH3_k127_5944873_10 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 395.0
WLSH3_k127_5944873_11 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007078 339.0
WLSH3_k127_5944873_12 PFAM HhH-GPD family protein K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 346.0
WLSH3_k127_5944873_13 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 303.0
WLSH3_k127_5944873_14 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 293.0
WLSH3_k127_5944873_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002305 263.0
WLSH3_k127_5944873_16 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000001478 220.0
WLSH3_k127_5944873_17 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000003574 240.0
WLSH3_k127_5944873_18 PAS domain K02030 - - 0.00000000000000000000000000000000000000000000000000001407 218.0
WLSH3_k127_5944873_19 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000001429 136.0
WLSH3_k127_5944873_2 Protein of unknown function, DUF255 K06888 - - 4.841e-257 811.0
WLSH3_k127_5944873_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.087e-223 707.0
WLSH3_k127_5944873_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 3.117e-220 689.0
WLSH3_k127_5944873_5 Rhodanese-like domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 584.0
WLSH3_k127_5944873_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 527.0
WLSH3_k127_5944873_7 PFAM Metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 454.0
WLSH3_k127_5944873_8 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 404.0
WLSH3_k127_5944873_9 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 405.0
WLSH3_k127_5978823_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 531.0
WLSH3_k127_5978823_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005412 231.0
WLSH3_k127_5978823_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000002038 218.0
WLSH3_k127_5978823_3 - - - - 0.0000000000000000000000000000000000000000000000000000001136 202.0
WLSH3_k127_5978823_4 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000000125 124.0
WLSH3_k127_5978823_5 - - - - 0.0000000000000821 74.0
WLSH3_k127_6027459_0 DEAD DEAH box helicase domain protein K10896 - - 0.0 1148.0
WLSH3_k127_6027459_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.0 1005.0
WLSH3_k127_6027459_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 494.0
WLSH3_k127_6027459_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 279.0
WLSH3_k127_6027459_4 - - - - 0.00000000000000000000000000000000000000000000001696 172.0
WLSH3_k127_6027459_5 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000000000000000000000000004949 166.0
WLSH3_k127_6027459_6 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000000000000000000000000000000000000005371 157.0
WLSH3_k127_6041975_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 430.0
WLSH3_k127_6041975_1 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 433.0
WLSH3_k127_6041975_2 ATP-grasp domain K06914 - 6.3.4.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 428.0
WLSH3_k127_6041975_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 349.0
WLSH3_k127_6041975_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 338.0
WLSH3_k127_6041975_5 - - - - 0.00000000000000000000000000000000000000000000000000000000003656 211.0
WLSH3_k127_6041975_6 Transcriptional regulator, TrmB - - - 0.0000000000000000000002788 100.0
WLSH3_k127_6041975_7 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000001694 93.0
WLSH3_k127_6093958_0 Ammonium Transporter K03320 - - 1.209e-227 708.0
WLSH3_k127_6093958_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 3.894e-201 630.0
WLSH3_k127_6093958_2 - - - - 7.555e-199 626.0
WLSH3_k127_6093958_3 Conserved region in glutamate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 517.0
WLSH3_k127_6093958_4 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 453.0
WLSH3_k127_6093958_5 Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 393.0
WLSH3_k127_6093958_6 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000005494 176.0
WLSH3_k127_6093958_7 - - - - 0.00000000000006543 78.0
WLSH3_k127_6109421_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 8.185e-214 677.0
WLSH3_k127_6109421_1 PFAM AAA ATPase central domain protein - - - 7.647e-210 658.0
WLSH3_k127_6109421_10 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000000000000000001168 139.0
WLSH3_k127_6109421_11 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000000000000000003384 120.0
WLSH3_k127_6109421_12 - - - - 0.00000000000000004445 83.0
WLSH3_k127_6109421_14 Acetyltransferase (GNAT) domain - - - 0.00004934 48.0
WLSH3_k127_6109421_2 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 539.0
WLSH3_k127_6109421_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 535.0
WLSH3_k127_6109421_4 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 527.0
WLSH3_k127_6109421_5 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 448.0
WLSH3_k127_6109421_6 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 405.0
WLSH3_k127_6109421_7 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.000000000000000000000000000000000000000000000000000000000000000001338 233.0
WLSH3_k127_6109421_8 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000003678 158.0
WLSH3_k127_6109421_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000167 154.0
WLSH3_k127_6110358_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 1.035e-244 771.0
WLSH3_k127_6110358_1 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000002096 234.0
WLSH3_k127_6110514_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 2.393e-243 767.0
WLSH3_k127_6110514_1 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000004353 236.0
WLSH3_k127_6145320_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1859.0
WLSH3_k127_6145320_1 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 4.379e-247 767.0
WLSH3_k127_6145320_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 289.0
WLSH3_k127_6145320_11 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 256.0
WLSH3_k127_6145320_12 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000003564 166.0
WLSH3_k127_6145320_13 - - - - 0.0000000000000000000000000000000000000000009522 158.0
WLSH3_k127_6145320_14 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000001089 162.0
WLSH3_k127_6145320_15 Glutaredoxin - - - 0.0000000000000000000000000000000001136 135.0
WLSH3_k127_6145320_16 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000003979 139.0
WLSH3_k127_6145320_17 Domain of unknown function DUF11 - - - 0.00000001542 66.0
WLSH3_k127_6145320_18 type I site-specific deoxyribonuclease activity K01153 - 3.1.21.3 0.00001955 52.0
WLSH3_k127_6145320_2 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 589.0
WLSH3_k127_6145320_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 519.0
WLSH3_k127_6145320_4 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 482.0
WLSH3_k127_6145320_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 409.0
WLSH3_k127_6145320_6 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004445 346.0
WLSH3_k127_6145320_7 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 342.0
WLSH3_k127_6145320_8 COG2406 Protein distantly related to bacterial ferritins K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 296.0
WLSH3_k127_6145320_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 298.0
WLSH3_k127_6153464_0 Flavodoxin domain - - - 0.000000000000000000000000000000000000006765 150.0
WLSH3_k127_6153464_1 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000001472 126.0
WLSH3_k127_6153464_2 TfoX N-terminal domain - - - 0.0000000001218 66.0
WLSH3_k127_6168745_0 TIGRFAM small GTP-binding protein K06944 - - 3.372e-209 655.0
WLSH3_k127_6168745_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 528.0
WLSH3_k127_6168745_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 305.0
WLSH3_k127_6168745_3 - - - - 0.000000000000000000000000000000001112 130.0
WLSH3_k127_6187839_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 4.101e-211 661.0
WLSH3_k127_6187839_1 Polyphosphate kinase 2 (PPK2) - - - 3.424e-200 638.0
WLSH3_k127_6187839_2 - K06868 - 2.5.1.73 0.0000000000000000002959 88.0
WLSH3_k127_6188316_0 Alpha beta hydrolase K01066,K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 363.0
WLSH3_k127_6188316_1 - - - - 0.00000000000000000000000000000000000000000000000001655 186.0
WLSH3_k127_6188316_2 - - - - 0.0000000002625 72.0
WLSH3_k127_6200806_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.0 1344.0
WLSH3_k127_6200806_1 Sodium hydrogen exchanger K03455 - - 2.131e-304 945.0
WLSH3_k127_6200806_10 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 542.0
WLSH3_k127_6200806_11 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 493.0
WLSH3_k127_6200806_12 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 410.0
WLSH3_k127_6200806_13 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 393.0
WLSH3_k127_6200806_14 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 391.0
WLSH3_k127_6200806_15 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 359.0
WLSH3_k127_6200806_16 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 342.0
WLSH3_k127_6200806_17 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 344.0
WLSH3_k127_6200806_18 Sodium hydrogen exchanger K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 346.0
WLSH3_k127_6200806_19 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 312.0
WLSH3_k127_6200806_2 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 4.291e-291 901.0
WLSH3_k127_6200806_20 Acetyltransferase (GNAT) family K21935 - 2.3.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 307.0
WLSH3_k127_6200806_21 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 299.0
WLSH3_k127_6200806_22 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 293.0
WLSH3_k127_6200806_23 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002891 273.0
WLSH3_k127_6200806_24 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002176 267.0
WLSH3_k127_6200806_25 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001386 261.0
WLSH3_k127_6200806_26 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001775 249.0
WLSH3_k127_6200806_27 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000151 240.0
WLSH3_k127_6200806_28 - K14093 - - 0.00000000000000000000000000000000000000000000000000000000000000119 222.0
WLSH3_k127_6200806_29 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000208 219.0
WLSH3_k127_6200806_3 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 6.541e-271 857.0
WLSH3_k127_6200806_30 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000004023 224.0
WLSH3_k127_6200806_31 Predicted membrane protein (DUF2105) K14098 - - 0.00000000000000000000000000000000000000000000000000000001026 205.0
WLSH3_k127_6200806_32 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000000000000000002459 199.0
WLSH3_k127_6200806_33 Domain of unknown function (DUF389) - - - 0.000000000000000000000000000000000000000000000000000008238 203.0
WLSH3_k127_6200806_34 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.0000000000000000000000000000000000000000000000005325 180.0
WLSH3_k127_6200806_35 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07324,K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000000000000002246 181.0
WLSH3_k127_6200806_36 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000004681 166.0
WLSH3_k127_6200806_37 small multi-drug export - - - 0.00000000000000000000000002252 117.0
WLSH3_k127_6200806_38 Ferredoxin K05337 - - 0.000000000000000000000002885 103.0
WLSH3_k127_6200806_39 PFAM molydopterin dinucleotide-binding region K00201,K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.00000000000000000000002277 104.0
WLSH3_k127_6200806_4 Transport of potassium into the cell K03549 - - 1.685e-256 803.0
WLSH3_k127_6200806_40 - - - - 0.0000000000000000000001145 109.0
WLSH3_k127_6200806_41 Predicted membrane protein (DUF2109) K14094 - - 0.000000000000000000004666 94.0
WLSH3_k127_6200806_42 Predicted membrane protein (DUF2107) K14096 - - 0.00000000000000000005683 93.0
WLSH3_k127_6200806_43 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07324,K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000001816 85.0
WLSH3_k127_6200806_44 Predicted membrane protein (DUF2108) K14095 - - 0.0000000001219 64.0
WLSH3_k127_6200806_45 PFAM regulatory protein, ArsR K21903 - - 0.000002515 51.0
WLSH3_k127_6200806_46 flavodoxin nitric oxide synthase K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016661,GO:0016662,GO:0016966,GO:0022900,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050664,GO:0055114,GO:0072593,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.3.4 0.000002521 58.0
WLSH3_k127_6200806_47 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.000009185 54.0
WLSH3_k127_6200806_5 4Fe-4S single cluster domain K01843 - 5.4.3.2 1.597e-232 728.0
WLSH3_k127_6200806_6 PFAM sodium hydrogen exchanger - - - 2.024e-217 680.0
WLSH3_k127_6200806_7 TIGRFAM lysine 2,3-aminomutase YodO family protein - - - 6.228e-203 636.0
WLSH3_k127_6200806_8 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 6.641e-196 618.0
WLSH3_k127_6200806_9 CBS domain containing protein K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 578.0
WLSH3_k127_6236647_0 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 441.0
WLSH3_k127_6236647_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008385 275.0
WLSH3_k127_6236647_2 TIGRFAM methyltransferase FkbM family - - - 0.000000000000000000000000000000000000000000000000000000000000004026 220.0
WLSH3_k127_6240124_0 by modhmm - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 319.0
WLSH3_k127_6240124_1 PFAM PKD domain containing protein - - - 0.0000000000005736 83.0
WLSH3_k127_6245677_0 Pas domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006498 299.0
WLSH3_k127_6245677_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002899 248.0
WLSH3_k127_6423834_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 0.0 1019.0
WLSH3_k127_6423834_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 400.0
WLSH3_k127_6423834_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 294.0
WLSH3_k127_6423834_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000009977 158.0
WLSH3_k127_6423834_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000000000000000000018 143.0
WLSH3_k127_6423834_5 - - - - 0.00000000000004254 78.0
WLSH3_k127_6439482_0 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000000005595 169.0
WLSH3_k127_6439482_1 Belongs to the UPF0248 family K09715 - - 0.00000000000000000000818 94.0
WLSH3_k127_6449881_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1699.0
WLSH3_k127_6449881_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 5.155e-271 835.0
WLSH3_k127_6449881_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 6.72e-226 704.0
WLSH3_k127_6449881_3 transcription termination protein NusA K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001209 280.0
WLSH3_k127_6449881_4 - - - - 0.0000000000000000000000000000000000000000000000000005039 198.0
WLSH3_k127_6449881_5 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000000000000000000000000000000000009533 181.0
WLSH3_k127_6449881_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000001807 125.0
WLSH3_k127_6455453_0 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000000002244 198.0
WLSH3_k127_6455453_1 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000001071 150.0
WLSH3_k127_6455453_2 HEAT repeats - - - 0.00000000000000000000000000001166 126.0
WLSH3_k127_6455453_3 domain protein K01186 - 3.2.1.18 0.000000000006045 81.0
WLSH3_k127_6455453_4 Periplasmic copper-binding protein (NosD) - - - 0.00000006837 68.0
WLSH3_k127_6514710_1 Pas domain - - - 0.000000000000000000008059 102.0
WLSH3_k127_6520889_0 ABC transporter K06147 - - 1.158e-275 858.0
WLSH3_k127_6520889_1 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000000000001701 189.0
WLSH3_k127_6520889_2 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000002646 164.0
WLSH3_k127_6564169_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 614.0
WLSH3_k127_6564169_1 PFAM Radical SAM domain protein K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 553.0
WLSH3_k127_6564169_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003988 419.0
WLSH3_k127_6564169_3 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000004215 214.0
WLSH3_k127_6564169_4 Phage plasmid primase, P4 K06919 - - 0.0000000000000000000000000000000003443 140.0
WLSH3_k127_6570983_0 PFAM Radical SAM domain protein K06871 - - 1.827e-206 647.0
WLSH3_k127_6570983_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00581 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 550.0
WLSH3_k127_6570983_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 498.0
WLSH3_k127_6570983_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 461.0
WLSH3_k127_6570983_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 439.0
WLSH3_k127_6570983_5 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 424.0
WLSH3_k127_6570983_6 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000002035 218.0
WLSH3_k127_6570983_7 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.0000000000000000000000000000000000000000000002872 169.0
WLSH3_k127_6570983_8 TIGRFAM tetrahydromethanopterin S-methyltransferase, F subunit K00582 - 2.1.1.86 0.0000000000000000000000003863 106.0
WLSH3_k127_6570983_9 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000002017 102.0
WLSH3_k127_6631684_0 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 4.555e-219 709.0
WLSH3_k127_6631684_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 574.0
WLSH3_k127_6631684_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 450.0
WLSH3_k127_6631684_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711,K15856 - 1.1.1.281,4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 445.0
WLSH3_k127_6631684_4 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 339.0
WLSH3_k127_6631684_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 288.0
WLSH3_k127_6631684_6 synthetase K18688 - 6.2.1.42 0.000000000000000000000000000000000000000000000000000000000000003713 225.0
WLSH3_k127_6631684_7 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000002499 215.0
WLSH3_k127_6631684_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000004432 162.0
WLSH3_k127_6639512_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000001014 202.0
WLSH3_k127_6639512_1 - - - - 0.000000000000000000264 94.0
WLSH3_k127_665474_0 EB module - - - 0.00000000001503 76.0
WLSH3_k127_665474_2 - - - - 0.00001418 55.0
WLSH3_k127_665474_3 - - - - 0.00002599 56.0
WLSH3_k127_6673947_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 316.0
WLSH3_k127_6673947_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001065 261.0
WLSH3_k127_6673947_2 Matrixin - - - 0.00000000000000000000000000000009138 127.0
WLSH3_k127_6673947_3 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000002309 124.0
WLSH3_k127_6759984_0 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 400.0
WLSH3_k127_6759984_1 - - - - 0.0000000000000000000000000000000000000000000000000000000125 211.0
WLSH3_k127_6759984_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000002807 154.0
WLSH3_k127_6759984_3 CBS domain - - - 0.000000000000000000000000000000004761 139.0
WLSH3_k127_6759984_4 - K16923 - - 0.000000000000000000003713 107.0
WLSH3_k127_6759984_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K18979 - 1.17.99.6 0.0000000000000002388 85.0
WLSH3_k127_6759984_6 - - - - 0.00000000002128 65.0
WLSH3_k127_6759984_7 Ion channel - - - 0.000001003 61.0
WLSH3_k127_6774083_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 3.674e-312 964.0
WLSH3_k127_6774083_1 Predicted membrane protein (DUF2070) K08979 - - 2.775e-276 859.0
WLSH3_k127_6774083_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 482.0
WLSH3_k127_6774083_11 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 434.0
WLSH3_k127_6774083_12 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 425.0
WLSH3_k127_6774083_13 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 413.0
WLSH3_k127_6774083_14 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
WLSH3_k127_6774083_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 335.0
WLSH3_k127_6774083_16 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 325.0
WLSH3_k127_6774083_17 Putative transposase DNA-binding domain K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 305.0
WLSH3_k127_6774083_18 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 291.0
WLSH3_k127_6774083_19 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 283.0
WLSH3_k127_6774083_2 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 8.479e-228 716.0
WLSH3_k127_6774083_20 Fumarase C-terminus K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003262 276.0
WLSH3_k127_6774083_21 PFAM extracellular solute-binding protein family 1 K02020,K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006267 268.0
WLSH3_k127_6774083_22 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002616 260.0
WLSH3_k127_6774083_23 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000009856 215.0
WLSH3_k127_6774083_24 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000001685 213.0
WLSH3_k127_6774083_25 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000001429 201.0
WLSH3_k127_6774083_26 Belongs to the UPF0212 family K09731 - - 0.00000000000000000000000000000000000000000000000000000001244 198.0
WLSH3_k127_6774083_27 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000001887 197.0
WLSH3_k127_6774083_28 Family of unknown function (DUF5350) - - - 0.00000000000000000000000000000000000000000006597 162.0
WLSH3_k127_6774083_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.46e-209 654.0
WLSH3_k127_6774083_30 - - - - 0.0000000000000000000000000000000005595 135.0
WLSH3_k127_6774083_31 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.000000000000000000000000000003286 124.0
WLSH3_k127_6774083_32 TIR domain - - - 0.000000000000000000000000000009982 124.0
WLSH3_k127_6774083_33 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0000000000000000000000000001327 115.0
WLSH3_k127_6774083_35 deoxyhypusine monooxygenase activity - - - 0.0000000000000007366 79.0
WLSH3_k127_6774083_36 - - - - 0.000000000192 67.0
WLSH3_k127_6774083_37 Nitrite and sulphite reductase 4Fe-4S - - - 0.0001643 45.0
WLSH3_k127_6774083_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 613.0
WLSH3_k127_6774083_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 533.0
WLSH3_k127_6774083_6 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 527.0
WLSH3_k127_6774083_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 516.0
WLSH3_k127_6774083_8 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 505.0
WLSH3_k127_6774083_9 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 481.0
WLSH3_k127_683196_0 Domain of unknown function (DUF814) - - - 1.776e-286 890.0
WLSH3_k127_683196_1 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 1.032e-264 834.0
WLSH3_k127_683196_10 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000005063 142.0
WLSH3_k127_683196_2 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 549.0
WLSH3_k127_683196_3 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 413.0
WLSH3_k127_683196_4 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 375.0
WLSH3_k127_683196_5 ISXO2-like transposase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 373.0
WLSH3_k127_683196_6 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006042 261.0
WLSH3_k127_683196_7 metallopeptidase activity - - - 0.000000000000000000000000000000000000002207 161.0
WLSH3_k127_683196_8 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000000000000102 151.0
WLSH3_k127_683196_9 TIR domain - - - 0.0000000000000000000000000000000000001084 147.0
WLSH3_k127_6834320_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 8.79e-277 857.0
WLSH3_k127_6834320_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 549.0
WLSH3_k127_6834320_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 507.0
WLSH3_k127_6834320_3 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 434.0
WLSH3_k127_6834320_4 Domain of unknown function DUF128 K21640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 383.0
WLSH3_k127_6834320_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 377.0
WLSH3_k127_6834320_6 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 288.0
WLSH3_k127_6834320_7 PFAM transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000007778 204.0
WLSH3_k127_6834320_8 PFAM TrkA-N domain protein K10716 - - 0.0000000000000008718 79.0
WLSH3_k127_684251_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 497.0
WLSH3_k127_684251_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 389.0
WLSH3_k127_684251_2 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 357.0
WLSH3_k127_684251_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 297.0
WLSH3_k127_684251_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002515 226.0
WLSH3_k127_684251_7 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000002244 153.0
WLSH3_k127_684251_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000003214 102.0
WLSH3_k127_684251_9 Putative DNA-binding domain - - - 0.000000000000000008576 95.0
WLSH3_k127_6848777_0 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 412.0
WLSH3_k127_6848777_1 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 429.0
WLSH3_k127_6848777_2 endopeptidase activity - - - 0.0000000000000001419 94.0
WLSH3_k127_6887319_0 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 3.655e-218 695.0
WLSH3_k127_6887319_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 493.0
WLSH3_k127_6887319_2 Chemotaxis signal transduction system protein F from archaea K09156 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 467.0
WLSH3_k127_6887319_3 CheC inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009541 262.0
WLSH3_k127_6887319_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001417 270.0
WLSH3_k127_6887319_5 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000004115 226.0
WLSH3_k127_6887319_6 type II secretion system protein K07333 - - 0.00000000000000000000000000000000000000000000000000000003119 200.0
WLSH3_k127_6992091_0 serine threonine protein kinase K12132 - 2.7.11.1 1.837e-201 649.0
WLSH3_k127_6992091_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 6.079e-195 614.0
WLSH3_k127_6992091_11 CYTH - - - 0.000000000001128 71.0
WLSH3_k127_6992091_12 PFAM Uncharacterised protein family UPF0066 - - - 0.000000000006779 67.0
WLSH3_k127_6992091_13 Protein of unknown function (DUF3795) - - - 0.00000000008382 65.0
WLSH3_k127_6992091_2 DNA polymerase beta domain protein region K09717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 499.0
WLSH3_k127_6992091_3 FHA domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 410.0
WLSH3_k127_6992091_4 PFAM amino acid-binding ACT domain protein K06862 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 393.0
WLSH3_k127_6992091_5 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 288.0
WLSH3_k127_6992091_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005726 288.0
WLSH3_k127_6992091_7 COG1881 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000006431 231.0
WLSH3_k127_6992091_8 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000001705 203.0
WLSH3_k127_6992091_9 - - - - 0.00000000000000000000000000000000000000000004971 165.0
WLSH3_k127_7054312_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 354.0
WLSH3_k127_7054312_1 integral membrane protein - - - 0.00000000000000000000000000000007751 134.0
WLSH3_k127_7070684_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1130.0
WLSH3_k127_7070684_1 AAA-like domain K06915 - - 7.626e-263 814.0
WLSH3_k127_7070684_2 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 5.407e-260 803.0
WLSH3_k127_7070684_3 PFAM formate nitrite transporter K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 501.0
WLSH3_k127_7070684_4 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000189 256.0
WLSH3_k127_7070684_5 - - - - 0.00000000000000000000000000000685 130.0
WLSH3_k127_7070684_6 - - - - 0.000000000000000000000000000128 120.0
WLSH3_k127_7098606_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 4.59e-298 926.0
WLSH3_k127_7098606_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 473.0
WLSH3_k127_7098606_2 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 447.0
WLSH3_k127_7098606_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 287.0
WLSH3_k127_711753_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 435.0
WLSH3_k127_711753_1 Uncharacterized protein domain (DUF2202) - - - 0.0000000000000000000000000000000000000000000000008417 183.0
WLSH3_k127_711753_2 - - - - 0.00000000000000000000000308 106.0
WLSH3_k127_711753_3 - - - - 0.00000000000000000008818 99.0
WLSH3_k127_711753_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000003906 80.0
WLSH3_k127_711753_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000002219 76.0
WLSH3_k127_711753_6 - K06198 - - 0.000000000000935 71.0
WLSH3_k127_711753_7 Protein conserved in bacteria - - - 0.00000000467 66.0
WLSH3_k127_7163721_0 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 329.0
WLSH3_k127_7163721_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 286.0
WLSH3_k127_7163721_10 peptidyl-tyrosine sulfation - - - 0.000002517 60.0
WLSH3_k127_7163721_11 - - - - 0.0001075 47.0
WLSH3_k127_7163721_2 PFAM Cache, type 2 domain protein - - - 0.000000000000000000000000000000001018 136.0
WLSH3_k127_7163721_3 acetyl-CoA hydrolase K18118,K18288 - 2.8.3.18 0.000000000000000000000000000000001865 133.0
WLSH3_k127_7163721_4 GYD domain - - - 0.000000000000000000000004867 105.0
WLSH3_k127_7163721_6 sh3 domain protein K12132,K15539 - 2.7.11.1 0.0000000000000006717 91.0
WLSH3_k127_7163721_7 PFAM TM2 domain containing protein - - - 0.00000000000000632 88.0
WLSH3_k127_7163721_9 - - - - 0.0000000001177 65.0
WLSH3_k127_7164374_0 Domain of unknown function (DUF3821) - - - 9.008e-281 891.0
WLSH3_k127_7164374_1 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 1.635e-275 853.0
WLSH3_k127_7164374_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 480.0
WLSH3_k127_7164374_3 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 424.0
WLSH3_k127_7180379_0 PFAM type II secretion system protein E K07332 - - 5e-324 997.0
WLSH3_k127_7180379_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.017e-235 736.0
WLSH3_k127_7180379_10 - - - - 0.00000000000000000000000000001209 128.0
WLSH3_k127_7180379_11 - - - - 0.0000000000000001329 87.0
WLSH3_k127_7180379_2 PFAM 4-vinyl reductase, 4VR K07013 - - 5.661e-203 635.0
WLSH3_k127_7180379_3 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 483.0
WLSH3_k127_7180379_4 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 416.0
WLSH3_k127_7180379_5 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 350.0
WLSH3_k127_7180379_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001197 235.0
WLSH3_k127_7180379_7 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000000000000001337 209.0
WLSH3_k127_7180379_8 Roadblock LC7 K07131 - - 0.0000000000000000000000000000000000000000000000000000000001421 204.0
WLSH3_k127_7180379_9 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000008749 183.0
WLSH3_k127_7243253_0 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 310.0
WLSH3_k127_7243253_1 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000004205 194.0
WLSH3_k127_7243253_2 Rubrerythrin - - - 0.0000000000000003609 79.0
WLSH3_k127_7243253_3 transcriptional regulators K03724 - - 0.0000000006801 60.0
WLSH3_k127_7312795_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 2.914e-198 623.0
WLSH3_k127_7312795_1 PFAM Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000004554 109.0
WLSH3_k127_7314000_0 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 365.0
WLSH3_k127_7314000_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 327.0
WLSH3_k127_7314000_2 membrane - - - 0.000000000000000163 90.0
WLSH3_k127_7332527_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 567.0
WLSH3_k127_7332527_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 369.0
WLSH3_k127_7343478_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 265.0
WLSH3_k127_7343478_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000005254 136.0
WLSH3_k127_7343478_2 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000002971 127.0
WLSH3_k127_7343478_3 - - - - 0.000000000000000000000000007609 113.0
WLSH3_k127_7343478_4 Winged helix-turn-helix - - - 0.00000000000000000000000005572 109.0
WLSH3_k127_7343478_5 GH3 auxin-responsive promoter - - - 0.00000000000000001308 85.0
WLSH3_k127_7343478_6 - - - - 0.00000000000008317 76.0
WLSH3_k127_7352294_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 332.0
WLSH3_k127_7352294_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000749 203.0
WLSH3_k127_7352294_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000002796 96.0
WLSH3_k127_7352294_3 - - - - 0.000000000000000000363 90.0
WLSH3_k127_7352294_4 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000006205 83.0
WLSH3_k127_7366620_0 AMP-binding enzyme - - - 1.761e-197 621.0
WLSH3_k127_7419314_0 transposase K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 416.0
WLSH3_k127_7419314_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000002973 165.0
WLSH3_k127_7419314_2 Subtilase family - - - 0.000000000000000000000000000006128 134.0
WLSH3_k127_747409_0 Nitrogenase component 1 type Oxidoreductase K02587 - - 0.0000000000000000000000000000000001769 140.0
WLSH3_k127_747409_1 membrane transporter protein K07090 - - 0.00000000000000001368 86.0
WLSH3_k127_747409_2 - - - - 0.0000000000000001351 87.0
WLSH3_k127_7506495_0 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000000008111 166.0
WLSH3_k127_7506495_1 - - - - 0.000000000000000000000000001353 113.0
WLSH3_k127_7506495_2 PFAM TPR repeat-containing protein - - - 0.000000000000000000001285 99.0
WLSH3_k127_7506495_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000007168 48.0
WLSH3_k127_7506577_0 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000001636 127.0
WLSH3_k127_7506577_1 - - - - 0.00000000000000000000000001242 111.0
WLSH3_k127_7506577_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000007168 48.0
WLSH3_k127_7511877_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 477.0
WLSH3_k127_7511877_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 309.0
WLSH3_k127_7511877_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 271.0
WLSH3_k127_7511877_3 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003017 259.0
WLSH3_k127_7511877_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000136 248.0
WLSH3_k127_7511877_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000003711 234.0
WLSH3_k127_7511877_6 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000000000000000000000000000000000000000000000000006769 220.0
WLSH3_k127_7511877_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000000001744 134.0
WLSH3_k127_7511877_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000000000000116 106.0
WLSH3_k127_7511877_9 metallopeptidase activity - - - 0.00000000001584 69.0
WLSH3_k127_7586674_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 5.057e-209 655.0
WLSH3_k127_7586674_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 6.016e-194 612.0
WLSH3_k127_7586674_2 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 531.0
WLSH3_k127_7586674_3 Domain of unknown function (DUF1743) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 488.0
WLSH3_k127_7586674_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 415.0
WLSH3_k127_7586674_5 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 383.0
WLSH3_k127_7586674_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 303.0
WLSH3_k127_7586674_7 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
WLSH3_k127_7586674_8 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000001692 255.0
WLSH3_k127_7586674_9 Domain of unknown function (DUF4142) - - - 0.000000003417 59.0
WLSH3_k127_7671877_0 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000001475 142.0
WLSH3_k127_7685040_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 7.318e-265 825.0
WLSH3_k127_7685040_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 2.236e-238 745.0
WLSH3_k127_7685040_2 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.462e-201 637.0
WLSH3_k127_7685040_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 447.0
WLSH3_k127_7685040_4 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 397.0
WLSH3_k127_7685040_5 COG3547 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 327.0
WLSH3_k127_7685040_6 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002714 279.0
WLSH3_k127_7711721_0 PFAM Radical SAM domain protein K06937 - - 1.595e-211 662.0
WLSH3_k127_7711721_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000005917 63.0
WLSH3_k127_77400_0 permease K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 552.0
WLSH3_k127_77400_1 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein K07485 - - 0.00000000000000000000000000000000000000000000000000000000000000009644 234.0
WLSH3_k127_77400_2 - - - - 0.0000000000005997 70.0
WLSH3_k127_77400_3 peptidyl-tyrosine sulfation - - - 0.000002478 59.0
WLSH3_k127_7785862_0 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 372.0
WLSH3_k127_7785862_1 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000001007 134.0
WLSH3_k127_7816539_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1780.0
WLSH3_k127_7816539_1 SMART Elongator protein 3 MiaB NifB - - - 2.369e-290 897.0
WLSH3_k127_7816539_10 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 314.0
WLSH3_k127_7816539_11 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 319.0
WLSH3_k127_7816539_12 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 289.0
WLSH3_k127_7816539_13 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000000000000000003199 164.0
WLSH3_k127_7816539_14 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000001019 138.0
WLSH3_k127_7816539_15 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000008366 111.0
WLSH3_k127_7816539_16 - - - - 0.000000000000000000000001384 105.0
WLSH3_k127_7816539_17 - - - - 0.00000000000000007607 81.0
WLSH3_k127_7816539_2 phosphoesterase RecJ domain protein - - - 1.435e-271 841.0
WLSH3_k127_7816539_21 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0004889 52.0
WLSH3_k127_7816539_3 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 2.478e-264 833.0
WLSH3_k127_7816539_4 PFAM Aldehyde dehydrogenase - - - 6.946e-230 720.0
WLSH3_k127_7816539_5 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 586.0
WLSH3_k127_7816539_6 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 567.0
WLSH3_k127_7816539_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 587.0
WLSH3_k127_7816539_8 tRNAHis guanylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 358.0
WLSH3_k127_7816539_9 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 341.0
WLSH3_k127_7840827_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 5.457e-246 766.0
WLSH3_k127_7840827_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000008577 149.0
WLSH3_k127_7995430_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.193e-213 669.0
WLSH3_k127_7995430_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 476.0
WLSH3_k127_7995430_2 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 372.0
WLSH3_k127_7995430_3 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001282 239.0
WLSH3_k127_7995430_4 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000002167 237.0
WLSH3_k127_7995430_5 PFAM SOUL heme-binding protein - - - 0.00000000000006281 72.0
WLSH3_k127_8014762_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 418.0
WLSH3_k127_8014762_1 transposase K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 352.0
WLSH3_k127_8014762_2 - - - - 0.0000000000000000000000000002706 116.0
WLSH3_k127_8014762_3 Protein of unknown function (DUF1566) - - - 0.00000000000001042 85.0
WLSH3_k127_8038878_0 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008044 280.0
WLSH3_k127_8038878_1 - - - - 0.0000000000000000000000000000003087 125.0
WLSH3_k127_8038878_2 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000284 124.0
WLSH3_k127_8065728_0 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 479.0
WLSH3_k127_8065728_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 393.0
WLSH3_k127_8065728_2 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 360.0
WLSH3_k127_8065728_3 DNA polymerase LigD, polymerase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000002921 242.0
WLSH3_k127_8065728_4 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000147 223.0
WLSH3_k127_8065728_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000002742 192.0
WLSH3_k127_8065728_6 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000001094 175.0
WLSH3_k127_8065728_7 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000004386 66.0
WLSH3_k127_8154845_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 366.0
WLSH3_k127_8154845_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000002597 102.0
WLSH3_k127_8180864_0 Heat shock 70 kDa protein K04043 - - 0.0 1062.0
WLSH3_k127_8180864_1 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 2.215e-260 808.0
WLSH3_k127_8180864_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 3.518e-204 640.0
WLSH3_k127_8180864_3 RNA methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 481.0
WLSH3_k127_8180864_4 PFAM regulatory protein, ArsR K07721 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 293.0
WLSH3_k127_8180864_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000001799 208.0
WLSH3_k127_8180864_6 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000000000000000000000000000000000005262 212.0
WLSH3_k127_8180864_7 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000001591 96.0
WLSH3_k127_8180864_8 KTSC domain - - - 0.0000000000000000696 82.0
WLSH3_k127_8180864_9 PFAM binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000653 63.0
WLSH3_k127_8188153_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 9.55e-211 665.0
WLSH3_k127_8188153_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 553.0
WLSH3_k127_8188153_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 509.0
WLSH3_k127_8188153_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009312 268.0
WLSH3_k127_8188153_4 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002985 259.0
WLSH3_k127_8188153_5 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000001353 104.0
WLSH3_k127_8188153_6 small multi-drug export - - - 0.00000000002654 68.0
WLSH3_k127_8291044_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1404.0
WLSH3_k127_8291044_1 PFAM ABC transporter K00400 - - 3.907e-310 955.0
WLSH3_k127_8291044_10 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 556.0
WLSH3_k127_8291044_11 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 507.0
WLSH3_k127_8291044_12 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 496.0
WLSH3_k127_8291044_13 PFAM Beta propeller domain K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 501.0
WLSH3_k127_8291044_14 glycosyl transferase, family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 470.0
WLSH3_k127_8291044_15 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 461.0
WLSH3_k127_8291044_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 443.0
WLSH3_k127_8291044_17 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 443.0
WLSH3_k127_8291044_18 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 386.0
WLSH3_k127_8291044_19 4-Hydroxyphenylpyruvate dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 376.0
WLSH3_k127_8291044_2 SMART Elongator protein 3 MiaB NifB - - - 3.837e-304 942.0
WLSH3_k127_8291044_20 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 327.0
WLSH3_k127_8291044_21 Pas domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 361.0
WLSH3_k127_8291044_22 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 318.0
WLSH3_k127_8291044_23 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 305.0
WLSH3_k127_8291044_24 involved in cell wall biogenesis K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 297.0
WLSH3_k127_8291044_25 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002607 272.0
WLSH3_k127_8291044_26 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000819 264.0
WLSH3_k127_8291044_27 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000218 261.0
WLSH3_k127_8291044_28 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005547 249.0
WLSH3_k127_8291044_29 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000004685 244.0
WLSH3_k127_8291044_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.77e-273 847.0
WLSH3_k127_8291044_30 involved in cell wall biogenesis K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000002142 202.0
WLSH3_k127_8291044_31 Histidine kinase A domain protein - - - 0.000000000000000000000000000009836 139.0
WLSH3_k127_8291044_32 Putative diguanylate phosphodiesterase - - - 0.0000006687 64.0
WLSH3_k127_8291044_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 9.046e-239 742.0
WLSH3_k127_8291044_5 PFAM ATPase, BadF BadG BcrA BcrD type - - - 1.07e-232 724.0
WLSH3_k127_8291044_6 Belongs to the UPF0288 family - - - 8.617e-231 724.0
WLSH3_k127_8291044_7 Predicted membrane protein (DUF2207) - - - 7.194e-230 726.0
WLSH3_k127_8291044_8 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 1.007e-229 718.0
WLSH3_k127_8291044_9 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 555.0
WLSH3_k127_8328538_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1351.0
WLSH3_k127_8328538_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 1.612e-204 644.0
WLSH3_k127_8328538_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000004718 149.0
WLSH3_k127_8328538_3 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.00000000000000000000000000000000001655 136.0
WLSH3_k127_8328538_4 zinc-ribbon domain - - - 0.0001491 49.0
WLSH3_k127_8418093_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 8.315e-238 747.0
WLSH3_k127_8418093_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.212e-213 666.0
WLSH3_k127_8418093_2 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 294.0
WLSH3_k127_8418093_3 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000001042 119.0
WLSH3_k127_8418093_4 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000000000000001474 100.0
WLSH3_k127_8509525_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 5.019e-287 884.0
WLSH3_k127_8509525_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 3.713e-215 672.0
WLSH3_k127_8509525_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 348.0
WLSH3_k127_8509525_3 - - - - 0.000000000000000000000000000000000000000000000000922 175.0
WLSH3_k127_8509525_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000001451 175.0
WLSH3_k127_8509525_5 - - - - 0.00000000000000000000000000000000000000001741 158.0
WLSH3_k127_8509525_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000003561 126.0
WLSH3_k127_8563482_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.797e-286 884.0
WLSH3_k127_8563482_1 PFAM phosphoesterase, RecJ domain protein K07463 - - 7.763e-266 822.0
WLSH3_k127_8563482_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.000000000000000000000000000000000000000000000000000000000000259 218.0
WLSH3_k127_8563482_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000000000000000000000000000000000000006469 194.0
WLSH3_k127_8563482_12 binds to the 23S rRNA K02921 - - 0.000000000000000000000000000000000000000000000001327 175.0
WLSH3_k127_8563482_13 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000000000000000000000000004653 171.0
WLSH3_k127_8563482_14 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000009526 110.0
WLSH3_k127_8563482_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000000002477 96.0
WLSH3_k127_8563482_16 PFAM PUA domain K07398 - - 0.00000000000000000001465 100.0
WLSH3_k127_8563482_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 9.873e-211 663.0
WLSH3_k127_8563482_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 467.0
WLSH3_k127_8563482_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 459.0
WLSH3_k127_8563482_5 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 422.0
WLSH3_k127_8563482_6 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 407.0
WLSH3_k127_8563482_7 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 339.0
WLSH3_k127_8563482_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002279 274.0
WLSH3_k127_8563482_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000011 235.0
WLSH3_k127_861834_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
WLSH3_k127_861834_1 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000001872 241.0
WLSH3_k127_861834_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004448 226.0
WLSH3_k127_861834_3 - - - - 0.00000000000000000000000004675 110.0
WLSH3_k127_861834_4 - - - - 0.000000000000000000000794 99.0
WLSH3_k127_861834_5 - - - - 0.0000000000001314 79.0
WLSH3_k127_861834_6 - - - - 0.000000000004788 72.0
WLSH3_k127_8621506_0 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 393.0
WLSH3_k127_8621506_1 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000245 247.0
WLSH3_k127_8621506_2 - - - - 0.0000000000000000000000000000000000000000000000000002055 199.0
WLSH3_k127_8621506_3 Roadblock LC7 - - - 0.000000000000000000006658 105.0
WLSH3_k127_8621506_4 Roadblock LC7 K07131 - - 0.00000000009943 68.0
WLSH3_k127_8621506_5 Histidine kinase K07651 - 2.7.13.3 0.000004795 54.0
WLSH3_k127_866326_0 Alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 352.0
WLSH3_k127_866326_1 CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005941 288.0
WLSH3_k127_866326_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001285 230.0
WLSH3_k127_866326_3 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000001898 203.0
WLSH3_k127_866326_4 META domain - - - 0.0000000000000000000000000000000000002518 151.0
WLSH3_k127_8697531_0 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 468.0
WLSH3_k127_8697531_1 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
WLSH3_k127_8697531_2 by modhmm - - - 0.000000000000000000000000000000000005636 153.0
WLSH3_k127_8697531_3 - - - - 0.000000000000000000000000000001446 122.0
WLSH3_k127_8740055_0 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 287.0
WLSH3_k127_8740055_1 Domain of unknown function (DUF1724) - - - 0.000000000000000000000000000000000000000000000000000000000000000000008265 242.0
WLSH3_k127_8740055_2 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000003864 178.0
WLSH3_k127_8740055_3 Belongs to the UPF0216 family K09737 - - 0.0000000000000000000000000000000000000000001829 164.0
WLSH3_k127_8740055_4 Serine protease with a broad substrate specificity K13276,K17734 - - 0.000000000000000000000000000000000000000002796 170.0
WLSH3_k127_8740055_5 PFAM transposase, IS4 family protein - - - 0.000000000000001143 81.0
WLSH3_k127_8740055_6 - - - - 0.000000000597 64.0
WLSH3_k127_8746237_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 587.0
WLSH3_k127_8746237_1 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 402.0
WLSH3_k127_8746237_2 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 333.0
WLSH3_k127_8746237_3 COG1202 Superfamily II helicase, archaea-specific - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002795 263.0
WLSH3_k127_8746237_4 Short repeat of unknown function (DUF308) - - - 0.000000000000000000000000000001388 127.0
WLSH3_k127_8746237_5 - - - - 0.00000000000000000001348 94.0
WLSH3_k127_875378_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1252.0
WLSH3_k127_875378_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 602.0
WLSH3_k127_875378_10 deoxyhypusine monooxygenase activity - - - 0.000001205 60.0
WLSH3_k127_875378_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 364.0
WLSH3_k127_875378_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000482 278.0
WLSH3_k127_875378_4 phosphoribosyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000013 271.0
WLSH3_k127_875378_5 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001455 255.0
WLSH3_k127_875378_6 AN1-like Zinc finger - - - 0.00000000000000000000000000000000000000000000000000000000000000002968 237.0
WLSH3_k127_875378_7 LamG domain protein jellyroll fold domain protein K01190,K22278 - 3.2.1.23,3.5.1.104 0.00000000000000000000000000000000000000000001937 184.0
WLSH3_k127_875378_8 - - - - 0.000000000000000000000000000000000000000001629 163.0
WLSH3_k127_875378_9 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000003992 125.0
WLSH3_k127_8762506_0 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000001062 239.0
WLSH3_k127_8762506_1 COG0471 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000004497 199.0
WLSH3_k127_8762506_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000007156 62.0
WLSH3_k127_8791523_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000001479 179.0
WLSH3_k127_8791523_1 PFAM NHL repeat containing protein - - - 0.000001563 54.0
WLSH3_k127_8814861_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.533e-270 836.0
WLSH3_k127_8814861_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 600.0
WLSH3_k127_8814861_2 Membrane protein of unknown function DUF63 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 442.0
WLSH3_k127_8814861_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000727 259.0
WLSH3_k127_8814861_4 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000000000000000000000000000000001166 237.0
WLSH3_k127_8814861_5 Stage II sporulation protein M K06384 - - 0.000000000000000000000000000000000000000000000000000000000001011 214.0
WLSH3_k127_8872381_0 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 2.427e-270 837.0
WLSH3_k127_8872381_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 1.126e-217 680.0
WLSH3_k127_8872381_2 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 1.642e-217 688.0
WLSH3_k127_8872381_3 Fe-S-cluster oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000006385 196.0
WLSH3_k127_8894609_0 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 606.0
WLSH3_k127_8894609_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 388.0
WLSH3_k127_8894609_2 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000000000000000000004949 239.0
WLSH3_k127_8894609_3 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000005778 156.0
WLSH3_k127_8894609_4 - - - - 0.0000000000000000000000000000000002778 138.0
WLSH3_k127_8894609_5 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000002232 118.0
WLSH3_k127_8894609_6 - - - - 0.00000000000008987 74.0
WLSH3_k127_8914905_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000863 105.0
WLSH3_k127_8983064_0 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 567.0
WLSH3_k127_8983064_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000002948 125.0
WLSH3_k127_8983064_2 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.000000000000000000000000204 109.0
WLSH3_k127_8983064_3 TPR repeat - - - 0.0000000000000000002618 102.0
WLSH3_k127_8983064_4 - - - - 0.000000000000004932 78.0
WLSH3_k127_900629_0 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 512.0
WLSH3_k127_900629_1 Permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 372.0
WLSH3_k127_900629_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001 240.0
WLSH3_k127_900629_3 Belongs to the UPF0248 family K09715 - - 0.00000000000000000000000000000000000009242 143.0
WLSH3_k127_900629_4 - - - - 0.00000000000000000000000000000000001996 141.0
WLSH3_k127_9053157_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 344.0
WLSH3_k127_9053157_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 322.0
WLSH3_k127_9053157_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000004333 241.0
WLSH3_k127_9053157_4 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000021 184.0
WLSH3_k127_9053157_5 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000001454 150.0
WLSH3_k127_9053157_6 Protein of unknown function (DUF1059) - - - 0.00005303 47.0
WLSH3_k127_9155983_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1488.0
WLSH3_k127_9155983_1 Belongs to the MCM family K10726 - - 0.0 1238.0
WLSH3_k127_9155983_10 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 564.0
WLSH3_k127_9155983_11 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 501.0
WLSH3_k127_9155983_12 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 497.0
WLSH3_k127_9155983_13 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 477.0
WLSH3_k127_9155983_14 Replication factor C K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 470.0
WLSH3_k127_9155983_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
WLSH3_k127_9155983_16 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 443.0
WLSH3_k127_9155983_17 Involved in protein export K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 407.0
WLSH3_k127_9155983_18 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 406.0
WLSH3_k127_9155983_19 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 365.0
WLSH3_k127_9155983_2 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.0 1085.0
WLSH3_k127_9155983_20 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 351.0
WLSH3_k127_9155983_21 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 344.0
WLSH3_k127_9155983_22 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 342.0
WLSH3_k127_9155983_23 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 339.0
WLSH3_k127_9155983_24 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 300.0
WLSH3_k127_9155983_25 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001042 272.0
WLSH3_k127_9155983_26 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000000009852 256.0
WLSH3_k127_9155983_27 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000004235 250.0
WLSH3_k127_9155983_28 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001503 250.0
WLSH3_k127_9155983_29 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003883 245.0
WLSH3_k127_9155983_3 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 6.23e-322 989.0
WLSH3_k127_9155983_30 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000001924 204.0
WLSH3_k127_9155983_31 - - - - 0.00000000000000000000000000000000000000000000002405 179.0
WLSH3_k127_9155983_32 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000122 171.0
WLSH3_k127_9155983_33 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000001224 171.0
WLSH3_k127_9155983_34 Protein of unknown function (DUF2551) - - - 0.000000000000000000000000000000000000000000006058 165.0
WLSH3_k127_9155983_35 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.0000000000000000000000000000000000003546 143.0
WLSH3_k127_9155983_36 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000000000000001878 140.0
WLSH3_k127_9155983_37 - - - - 0.000000000000000000000000000000000002576 140.0
WLSH3_k127_9155983_38 - - - - 0.00000000000000000000000000000000004583 140.0
WLSH3_k127_9155983_39 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000001229 116.0
WLSH3_k127_9155983_4 beta-lactamase domain protein - - - 1.408e-229 720.0
WLSH3_k127_9155983_40 - - - - 0.00004465 50.0
WLSH3_k127_9155983_41 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.0001193 46.0
WLSH3_k127_9155983_5 Protein-export membrane protein SecD K03072 - - 6.555e-227 713.0
WLSH3_k127_9155983_6 PFAM AIR synthase related protein K07388 - - 2.207e-217 681.0
WLSH3_k127_9155983_7 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 589.0
WLSH3_k127_9155983_8 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 588.0
WLSH3_k127_9155983_9 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 570.0
WLSH3_k127_9165403_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 6.078e-272 845.0
WLSH3_k127_9165403_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 477.0
WLSH3_k127_9165403_10 response regulator, receiver K09760 - - 0.0000000000000000000000000000000001646 140.0
WLSH3_k127_9165403_11 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000009207 125.0
WLSH3_k127_9165403_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 413.0
WLSH3_k127_9165403_3 PFAM GTP-binding protein HSR1-related K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 406.0
WLSH3_k127_9165403_4 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 334.0
WLSH3_k127_9165403_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 329.0
WLSH3_k127_9165403_6 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 321.0
WLSH3_k127_9165403_7 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 286.0
WLSH3_k127_9165403_8 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000000000000000000000000000001806 219.0
WLSH3_k127_9165403_9 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000008662 190.0
WLSH3_k127_9192479_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1663.0
WLSH3_k127_9192479_1 PFAM PilT protein domain protein K06865 - - 0.0 1076.0
WLSH3_k127_9192479_10 Ferredoxin K05337 - - 0.0000000000000000001745 91.0
WLSH3_k127_9192479_12 TIR domain - - - 0.0002292 53.0
WLSH3_k127_9192479_2 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 548.0
WLSH3_k127_9192479_3 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 400.0
WLSH3_k127_9192479_4 LVIVD repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 402.0
WLSH3_k127_9192479_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000000000000002199 224.0
WLSH3_k127_9192479_6 WD-40 repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000002487 238.0
WLSH3_k127_9192479_7 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000000000000000000000000000000000000006979 198.0
WLSH3_k127_9192479_8 - - - - 0.00000000000000000000000000000000000000000006496 161.0
WLSH3_k127_9192479_9 - - - - 0.0000000000000000000000000000000000357 150.0
WLSH3_k127_9204991_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.0 1195.0
WLSH3_k127_9204991_1 DEAD DEAH box helicase domain protein K03725 - - 0.0 1163.0
WLSH3_k127_9204991_10 - - - - 0.000000000000000002918 85.0
WLSH3_k127_9204991_11 Domain of unknown function (DUF4405) - - - 0.00000294 52.0
WLSH3_k127_9204991_2 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 543.0
WLSH3_k127_9204991_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 482.0
WLSH3_k127_9204991_4 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 477.0
WLSH3_k127_9204991_5 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 392.0
WLSH3_k127_9204991_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 297.0
WLSH3_k127_9204991_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000000000000000008674 150.0
WLSH3_k127_9204991_8 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000008664 151.0
WLSH3_k127_9204991_9 Phage plasmid primase, P4 K06919 - - 0.0000000000000000000000000000000000002434 145.0
WLSH3_k127_9222683_0 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 325.0
WLSH3_k127_9222683_1 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00000000000000000000000000000000000000004613 156.0
WLSH3_k127_9222683_2 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000001383 72.0
WLSH3_k127_9289144_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 6.219e-212 664.0
WLSH3_k127_9289144_1 PFAM metallophosphoesterase - - - 0.000000000000000000000000000282 128.0
WLSH3_k127_9289144_2 PFAM HEAT repeat - - - 0.0004414 48.0
WLSH3_k127_9378667_0 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.00000000000000000000000001321 119.0
WLSH3_k127_9378667_1 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000000000000000001252 95.0
WLSH3_k127_9378667_2 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000001387 93.0
WLSH3_k127_9409558_0 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 571.0
WLSH3_k127_9409558_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 361.0
WLSH3_k127_9409558_2 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001678 264.0
WLSH3_k127_9409558_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001506 255.0
WLSH3_k127_9450422_0 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000112 192.0
WLSH3_k127_9450422_1 - - - - 0.00000000000000000000000000000000000000000000000000002693 189.0
WLSH3_k127_9450422_2 - - - - 0.0000000000000000000000000000000000000003738 157.0
WLSH3_k127_9450422_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000001602 61.0
WLSH3_k127_9540482_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.861e-230 719.0
WLSH3_k127_9540482_1 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 609.0
WLSH3_k127_9540482_2 PFAM glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000119 167.0
WLSH3_k127_9540482_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000006851 158.0
WLSH3_k127_9540482_4 - - - - 0.00000000000000000000000000000000001564 141.0
WLSH3_k127_9540482_5 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000005312 127.0
WLSH3_k127_9552174_0 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 578.0
WLSH3_k127_9552174_1 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 526.0
WLSH3_k127_9552174_2 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003613 257.0
WLSH3_k127_9552174_3 Short repeat of unknown function (DUF308) - - - 0.000000000000001895 78.0
WLSH3_k127_9552174_4 - - - - 0.000000000000169 74.0
WLSH3_k127_956640_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 314.0
WLSH3_k127_9620532_0 Protein of unknown function (DUF460) K09150 - - 0.0 1009.0
WLSH3_k127_9620532_1 PFAM TrkA-N domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 556.0
WLSH3_k127_9620532_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 439.0
WLSH3_k127_9620532_3 Rio2, N-terminal K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 297.0
WLSH3_k127_9620532_4 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
WLSH3_k127_9620532_5 - - - - 0.0000000000000005506 84.0
WLSH3_k127_9620532_6 metallopeptidase activity - - - 0.00000002984 65.0
WLSH3_k127_9645177_0 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008824 248.0
WLSH3_k127_9645177_1 glucosylceramidase activity - - - 0.000000000000000000000000000000001345 134.0
WLSH3_k127_9645177_2 - - - - 0.00000000000000000000000000000005079 128.0
WLSH3_k127_9645177_3 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000000002812 116.0
WLSH3_k127_9645177_4 Belongs to the UPF0248 family K09715 - - 0.0000000000182 64.0
WLSH3_k127_9648670_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 2.381e-251 779.0
WLSH3_k127_9648670_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
WLSH3_k127_9648670_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 384.0
WLSH3_k127_9648670_3 Helix-turn-helix domain protein K03627 - - 0.000000000000000000000000000000000000000000000000000000000000000000007115 237.0
WLSH3_k127_9648670_4 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.000000000000000000000000000000000000000000000000000000000000002949 218.0
WLSH3_k127_9648670_5 - - - - 0.00000000000000000000000000000000000000000000002892 175.0
WLSH3_k127_9648670_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000000000000002576 141.0
WLSH3_k127_9648670_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000001272 107.0
WLSH3_k127_9683176_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000004658 126.0
WLSH3_k127_9683176_1 transposase K07497 - - 0.00000000000000000000000006876 108.0
WLSH3_k127_9683176_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.0000000000000000000000003417 107.0
WLSH3_k127_9683176_3 amino acid K03294 - - 0.000002197 54.0
WLSH3_k127_9683176_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000462 48.0
WLSH3_k127_9703400_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 455.0
WLSH3_k127_9703400_1 lyase activity - - - 0.0000000000000000000000000000000000000000000000000001543 197.0
WLSH3_k127_9703400_2 Regulatory protein, FmdB family - - - 0.0000000000000001753 83.0
WLSH3_k127_9727786_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1580.0
WLSH3_k127_9727786_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.399e-264 820.0
WLSH3_k127_9727786_10 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 381.0
WLSH3_k127_9727786_11 PFAM thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 347.0
WLSH3_k127_9727786_12 cytidyltransferase-related domain K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 292.0
WLSH3_k127_9727786_13 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 287.0
WLSH3_k127_9727786_14 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008746 280.0
WLSH3_k127_9727786_15 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000005586 236.0
WLSH3_k127_9727786_16 - - - - 0.00000000000000000000000000000000000000000000000000000006927 200.0
WLSH3_k127_9727786_17 - - - - 0.0000000000000000000000000000000000000000000000000006516 186.0
WLSH3_k127_9727786_18 - - - - 0.0000000000000000000000000000002815 125.0
WLSH3_k127_9727786_19 - - - - 0.0000000000000000000000000002408 115.0
WLSH3_k127_9727786_2 TGS domain protein K06942 - - 1.075e-213 667.0
WLSH3_k127_9727786_20 Possibly the antitoxin component of a - - - 0.00000000000000000000000007792 107.0
WLSH3_k127_9727786_21 Protein of unknown function DUF58 - - - 0.000000000000000001691 91.0
WLSH3_k127_9727786_3 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 3.766e-210 662.0
WLSH3_k127_9727786_4 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 546.0
WLSH3_k127_9727786_5 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 485.0
WLSH3_k127_9727786_6 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 412.0
WLSH3_k127_9727786_7 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 390.0
WLSH3_k127_9727786_8 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 384.0
WLSH3_k127_9727786_9 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 379.0
WLSH3_k127_9800239_0 PFAM type II secretion system protein E K07332 - - 0.0 1146.0
WLSH3_k127_9800239_1 type II secretion system protein K07333 - - 4.282e-247 772.0
WLSH3_k127_9800239_2 KaiC K07331 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 459.0
WLSH3_k127_9800239_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 361.0
WLSH3_k127_9800239_4 photosystem II stabilization K02237 - - 0.000000000000000000000000000000000000000000000000001808 195.0
WLSH3_k127_9800239_5 Archaebacterial flagellin K07330 - - 0.0000000000000000000000000000000000000000000198 167.0
WLSH3_k127_9800239_6 Archaeal flagellar protein F K07329 - - 0.00000000000000000000000000000003199 131.0
WLSH3_k127_9857965_0 Belongs to the peptidase S16 family - - - 1.587e-253 805.0
WLSH3_k127_9857965_1 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000000000001006 159.0
WLSH3_k127_9857965_2 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000001201 115.0
WLSH3_k127_9857965_3 - - - - 0.0000000000005114 78.0
WLSH3_k127_999080_0 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000731 153.0
WLSH3_k127_999080_1 Phosphoribosyl transferase domain K07101 - - 0.00000000001306 66.0