Overview

ID MAG04243
Name WLSH3_bin.23
Sample SMP0111
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus UBA9653
Species
Assembly information
Completeness (%) 94.5
Contamination (%) 5.41
GC content (%) 62.0
N50 (bp) 13,168
Genome size (bp) 1,692,646

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1537

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH3_k127_10041301_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 510.0
WLSH3_k127_10041301_1 Belongs to the UPF0434 family K09791 - - 0.0000000002353 61.0
WLSH3_k127_10041301_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000003909 60.0
WLSH3_k127_10049457_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 303.0
WLSH3_k127_10049457_1 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000002359 186.0
WLSH3_k127_10049457_2 Response regulator receiver domain - - - 0.0000000000000000001232 93.0
WLSH3_k127_10049457_3 Roadblock LC7 family protein K07131 - - 0.0000000000007358 74.0
WLSH3_k127_10049678_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1167.0
WLSH3_k127_10049678_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 6.013e-250 799.0
WLSH3_k127_10049678_10 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000004967 81.0
WLSH3_k127_10049678_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000001853 265.0
WLSH3_k127_10049678_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001155 244.0
WLSH3_k127_10049678_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000001809 213.0
WLSH3_k127_10049678_5 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003278 205.0
WLSH3_k127_10049678_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000001014 189.0
WLSH3_k127_10049678_7 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000001557 160.0
WLSH3_k127_10049678_8 VIT family - - - 0.0000000000000000000000000000000000001602 148.0
WLSH3_k127_10049678_9 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000004303 111.0
WLSH3_k127_10063183_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 400.0
WLSH3_k127_10063183_1 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000008756 233.0
WLSH3_k127_10063183_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000003858 181.0
WLSH3_k127_10063183_3 - - - - 0.000000000000000000000000000000001805 136.0
WLSH3_k127_10063183_4 - - - - 0.0000000000000000000000000001753 121.0
WLSH3_k127_10063968_0 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 400.0
WLSH3_k127_10063968_1 Domains REC, HisKA, HATPase_c - - - 0.0000000000000000000000000000000000000000000009968 186.0
WLSH3_k127_10063968_2 EamA-like transporter family K15268 - - 0.0008789 47.0
WLSH3_k127_10099350_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.189e-212 671.0
WLSH3_k127_10099350_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 325.0
WLSH3_k127_10099350_10 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000002341 202.0
WLSH3_k127_10099350_11 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000006547 183.0
WLSH3_k127_10099350_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001387 181.0
WLSH3_k127_10099350_13 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000005421 164.0
WLSH3_k127_10099350_14 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000007896 161.0
WLSH3_k127_10099350_15 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001164 166.0
WLSH3_k127_10099350_16 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000008747 154.0
WLSH3_k127_10099350_17 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001732 151.0
WLSH3_k127_10099350_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001146 150.0
WLSH3_k127_10099350_19 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000005996 139.0
WLSH3_k127_10099350_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 317.0
WLSH3_k127_10099350_20 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005627 102.0
WLSH3_k127_10099350_21 ribosomal protein S14 K02954 - - 0.00000000000000001162 91.0
WLSH3_k127_10099350_22 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000006403 72.0
WLSH3_k127_10099350_23 - - - - 0.0000000000008425 72.0
WLSH3_k127_10099350_3 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008308 295.0
WLSH3_k127_10099350_4 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
WLSH3_k127_10099350_5 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002202 229.0
WLSH3_k127_10099350_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000175 210.0
WLSH3_k127_10099350_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000513 204.0
WLSH3_k127_10099350_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002446 199.0
WLSH3_k127_10099350_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000005967 194.0
WLSH3_k127_10275287_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.219e-231 729.0
WLSH3_k127_10275287_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000001384 117.0
WLSH3_k127_10275287_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00006179 51.0
WLSH3_k127_10326435_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 612.0
WLSH3_k127_10326435_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002335 269.0
WLSH3_k127_10326435_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000007956 194.0
WLSH3_k127_10326435_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000006759 59.0
WLSH3_k127_10370587_0 Required for chromosome condensation and partitioning K03529 - - 1.809e-258 840.0
WLSH3_k127_10370587_1 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 480.0
WLSH3_k127_10370587_10 and related - - - 0.00000000000000000000000000000000000000000000000000005554 200.0
WLSH3_k127_10370587_11 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000000001967 191.0
WLSH3_k127_10370587_12 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000004446 195.0
WLSH3_k127_10370587_13 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000001002 183.0
WLSH3_k127_10370587_14 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.00000000000000000000000000000000000000000002385 167.0
WLSH3_k127_10370587_15 - - - - 0.000000000000000000000000000000000000000002581 160.0
WLSH3_k127_10370587_16 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000002762 163.0
WLSH3_k127_10370587_17 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000002441 157.0
WLSH3_k127_10370587_18 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000004418 159.0
WLSH3_k127_10370587_19 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000004618 151.0
WLSH3_k127_10370587_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 428.0
WLSH3_k127_10370587_20 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000001426 144.0
WLSH3_k127_10370587_21 Thiamine-binding protein - - - 0.00000000000000000000000001474 113.0
WLSH3_k127_10370587_22 Pkd domain containing protein - - - 0.000000000000000000000006578 118.0
WLSH3_k127_10370587_23 spore germination - - - 0.0000000000000000004382 98.0
WLSH3_k127_10370587_3 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 377.0
WLSH3_k127_10370587_4 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 368.0
WLSH3_k127_10370587_5 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 349.0
WLSH3_k127_10370587_6 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 361.0
WLSH3_k127_10370587_7 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 305.0
WLSH3_k127_10370587_8 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008602 264.0
WLSH3_k127_10370587_9 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000001 212.0
WLSH3_k127_10519833_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 462.0
WLSH3_k127_10519833_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 396.0
WLSH3_k127_10519833_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 343.0
WLSH3_k127_10519833_3 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 295.0
WLSH3_k127_10519833_4 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000009437 253.0
WLSH3_k127_10519833_5 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000001392 227.0
WLSH3_k127_10519833_6 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
WLSH3_k127_10519833_7 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000007842 180.0
WLSH3_k127_10685676_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 395.0
WLSH3_k127_10685676_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000002706 133.0
WLSH3_k127_10685676_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000004329 98.0
WLSH3_k127_10839490_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 552.0
WLSH3_k127_10839490_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 490.0
WLSH3_k127_10839490_2 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000001219 186.0
WLSH3_k127_10839490_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000004238 182.0
WLSH3_k127_10839490_4 PFAM PKD domain containing protein - - - 0.00000000000000000001109 109.0
WLSH3_k127_10919838_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008475 521.0
WLSH3_k127_10919838_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 466.0
WLSH3_k127_10919838_10 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000000000000000000000000000001103 167.0
WLSH3_k127_10919838_11 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000002972 145.0
WLSH3_k127_10919838_12 Bacterial PH domain - - - 0.00000000002118 74.0
WLSH3_k127_10919838_13 Protein of unknown function, DUF255 K06888 - - 0.0000000001619 71.0
WLSH3_k127_10919838_14 Rubrerythrin - - - 0.0000001961 63.0
WLSH3_k127_10919838_2 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 421.0
WLSH3_k127_10919838_3 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 401.0
WLSH3_k127_10919838_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 374.0
WLSH3_k127_10919838_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 337.0
WLSH3_k127_10919838_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000132 274.0
WLSH3_k127_10919838_7 isomerase activity K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000641 266.0
WLSH3_k127_10919838_8 conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003283 265.0
WLSH3_k127_10919838_9 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000001066 199.0
WLSH3_k127_10958650_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000003574 180.0
WLSH3_k127_11014153_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000001629 216.0
WLSH3_k127_11014153_1 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000325 83.0
WLSH3_k127_11014153_2 Major facilitator superfamily - - - 0.00000000005176 67.0
WLSH3_k127_11014153_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000003954 59.0
WLSH3_k127_11014153_4 40-residue YVTN family beta-propeller repeat - - - 0.000001242 62.0
WLSH3_k127_11065806_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 498.0
WLSH3_k127_11223123_0 AAA domain K01338 - 3.4.21.53 7.14e-201 637.0
WLSH3_k127_11223123_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 480.0
WLSH3_k127_11223123_10 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000004653 110.0
WLSH3_k127_11223123_11 Pfam:DUF59 - - - 0.0000000000000000157 85.0
WLSH3_k127_11223123_12 thiamineS protein K03154 - - 0.0000000002981 64.0
WLSH3_k127_11223123_2 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 484.0
WLSH3_k127_11223123_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 440.0
WLSH3_k127_11223123_4 Toprim domain K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 435.0
WLSH3_k127_11223123_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001257 251.0
WLSH3_k127_11223123_6 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000009328 203.0
WLSH3_k127_11223123_7 deoxyribonuclease I activity K06131,K06915 - - 0.000000000000000000000000000000000000000000000005858 195.0
WLSH3_k127_11223123_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000005665 169.0
WLSH3_k127_11223123_9 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000001165 114.0
WLSH3_k127_11236139_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 557.0
WLSH3_k127_11236139_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 386.0
WLSH3_k127_11236139_2 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 306.0
WLSH3_k127_11236139_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000006265 239.0
WLSH3_k127_11236139_4 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000008053 212.0
WLSH3_k127_11236139_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000001073 178.0
WLSH3_k127_11236139_6 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000002638 120.0
WLSH3_k127_11236139_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000007219 89.0
WLSH3_k127_11236139_8 ACT domain protein - - - 0.0000000002561 66.0
WLSH3_k127_11249974_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 322.0
WLSH3_k127_11249974_1 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004157 242.0
WLSH3_k127_11249974_2 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000001304 237.0
WLSH3_k127_11249974_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000000002071 114.0
WLSH3_k127_11249974_4 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000001858 79.0
WLSH3_k127_11333469_0 4Fe-4S single cluster domain K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 493.0
WLSH3_k127_11333469_1 glutathione-regulated potassium exporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003488 284.0
WLSH3_k127_11333469_2 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000005377 218.0
WLSH3_k127_11333469_3 Lamin Tail Domain - - - 0.0000000004493 74.0
WLSH3_k127_11417544_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.509e-262 835.0
WLSH3_k127_11417544_1 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 571.0
WLSH3_k127_11417544_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 372.0
WLSH3_k127_11417544_3 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000001091 246.0
WLSH3_k127_11417544_4 - - - - 0.00000000000000000000000000000000000000000000000002138 189.0
WLSH3_k127_11417544_5 COG0328 Ribonuclease HI K03469 - 3.1.26.4 0.0000000000000363 75.0
WLSH3_k127_11417544_6 acetyltransferase - - - 0.0005698 51.0
WLSH3_k127_1254859_0 helicase superfamily c-terminal domain K03724 - - 4.193e-302 953.0
WLSH3_k127_1254859_1 Cell division protein 48, CDC48, domain 2 K13525 - - 5.704e-274 861.0
WLSH3_k127_1254859_10 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 407.0
WLSH3_k127_1254859_11 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 399.0
WLSH3_k127_1254859_12 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 359.0
WLSH3_k127_1254859_13 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 342.0
WLSH3_k127_1254859_14 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 335.0
WLSH3_k127_1254859_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 327.0
WLSH3_k127_1254859_16 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 331.0
WLSH3_k127_1254859_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 351.0
WLSH3_k127_1254859_18 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 313.0
WLSH3_k127_1254859_19 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 309.0
WLSH3_k127_1254859_2 Type II/IV secretion system protein K07332 - - 2.724e-224 709.0
WLSH3_k127_1254859_20 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002211 280.0
WLSH3_k127_1254859_21 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001709 286.0
WLSH3_k127_1254859_22 HisG, C-terminal domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000008092 268.0
WLSH3_k127_1254859_23 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 256.0
WLSH3_k127_1254859_24 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000722 253.0
WLSH3_k127_1254859_25 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009377 242.0
WLSH3_k127_1254859_26 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000003605 240.0
WLSH3_k127_1254859_27 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001223 231.0
WLSH3_k127_1254859_28 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000203 215.0
WLSH3_k127_1254859_29 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000002639 213.0
WLSH3_k127_1254859_3 Type II/IV secretion system protein K07332 - - 4.927e-224 709.0
WLSH3_k127_1254859_30 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000003269 211.0
WLSH3_k127_1254859_31 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000004129 207.0
WLSH3_k127_1254859_32 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000003966 199.0
WLSH3_k127_1254859_33 Protein of unknown function (DUF531) K09725 - - 0.000000000000000000000000000000000000000000000000000001759 197.0
WLSH3_k127_1254859_34 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000901 203.0
WLSH3_k127_1254859_35 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000001557 206.0
WLSH3_k127_1254859_36 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000003098 208.0
WLSH3_k127_1254859_37 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000004958 197.0
WLSH3_k127_1254859_38 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000006259 193.0
WLSH3_k127_1254859_39 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000008624 181.0
WLSH3_k127_1254859_4 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 617.0
WLSH3_k127_1254859_40 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000001595 180.0
WLSH3_k127_1254859_41 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000002892 175.0
WLSH3_k127_1254859_42 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000003569 194.0
WLSH3_k127_1254859_43 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000006431 174.0
WLSH3_k127_1254859_44 Double zinc ribbon - - - 0.000000000000000000000000000000000000000000008212 188.0
WLSH3_k127_1254859_45 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000000000000008653 173.0
WLSH3_k127_1254859_46 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000007899 157.0
WLSH3_k127_1254859_47 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000005966 159.0
WLSH3_k127_1254859_48 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000000002195 149.0
WLSH3_k127_1254859_49 - - - - 0.0000000000000000000000000000000000004862 150.0
WLSH3_k127_1254859_5 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 566.0
WLSH3_k127_1254859_50 - - - - 0.000000000000000000000000000001264 138.0
WLSH3_k127_1254859_51 hmm pf03415 K08587 - 3.4.22.8 0.000000000000000000000000102 121.0
WLSH3_k127_1254859_52 PRC-barrel domain - - - 0.0000000000000000000000002149 107.0
WLSH3_k127_1254859_53 - - - - 0.000000000000000000000000374 110.0
WLSH3_k127_1254859_54 protein conserved in archaea - - - 0.000000000000000000000001316 106.0
WLSH3_k127_1254859_55 Nitroreductase family K19285,K19286 - 1.5.1.38,1.5.1.39 0.00000000000000000000004554 109.0
WLSH3_k127_1254859_56 toxin activity - - - 0.00000000000000000000006325 110.0
WLSH3_k127_1254859_57 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000001382 109.0
WLSH3_k127_1254859_58 PFAM Forkhead-associated protein - - - 0.0000000000000000000004058 109.0
WLSH3_k127_1254859_59 cheY-homologous receiver domain K03413 - - 0.00000000000000000004066 94.0
WLSH3_k127_1254859_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 535.0
WLSH3_k127_1254859_60 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000006401 85.0
WLSH3_k127_1254859_61 response to oxidative stress K04063 - - 0.0000000000000003983 85.0
WLSH3_k127_1254859_62 Tetratricopeptide repeat - - - 0.00000000000000356 89.0
WLSH3_k127_1254859_63 PRC-barrel domain protein - - - 0.00000000000008637 76.0
WLSH3_k127_1254859_64 Glutamine amidotransferases class-II - - - 0.0000000000003874 78.0
WLSH3_k127_1254859_65 Acetyltransferase, gnat family - - - 0.0000000000004585 79.0
WLSH3_k127_1254859_66 but it may be involved in stabilization of the trimeric complex - - - 0.0000000003326 62.0
WLSH3_k127_1254859_67 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000006067 65.0
WLSH3_k127_1254859_69 - - - - 0.000002384 55.0
WLSH3_k127_1254859_7 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 516.0
WLSH3_k127_1254859_70 - - - - 0.000002733 55.0
WLSH3_k127_1254859_72 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000005464 60.0
WLSH3_k127_1254859_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 472.0
WLSH3_k127_1254859_9 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 452.0
WLSH3_k127_1425344_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 521.0
WLSH3_k127_1425344_1 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000252 61.0
WLSH3_k127_1425344_2 Gcn5-related n-acetyltransferase - - - 0.0002214 49.0
WLSH3_k127_1528151_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.203e-240 756.0
WLSH3_k127_1528151_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 6.001e-221 708.0
WLSH3_k127_1528151_2 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 414.0
WLSH3_k127_1528151_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
WLSH3_k127_1671898_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 6.144e-273 861.0
WLSH3_k127_1671898_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.791e-211 671.0
WLSH3_k127_1671898_10 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000000000000001423 124.0
WLSH3_k127_1671898_11 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000001388 127.0
WLSH3_k127_1671898_12 Fcf1 K07158 - - 0.0000000000000000000000319 103.0
WLSH3_k127_1671898_13 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000006651 96.0
WLSH3_k127_1671898_14 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000174 93.0
WLSH3_k127_1671898_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 560.0
WLSH3_k127_1671898_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 461.0
WLSH3_k127_1671898_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
WLSH3_k127_1671898_5 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004856 272.0
WLSH3_k127_1671898_6 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000002092 223.0
WLSH3_k127_1671898_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000002393 207.0
WLSH3_k127_1671898_8 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000009612 170.0
WLSH3_k127_1671898_9 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000002994 161.0
WLSH3_k127_1673759_0 - - - - 0.000000000000000000933 94.0
WLSH3_k127_1673759_1 - - - - 0.000001849 57.0
WLSH3_k127_1673759_2 Tetratricopeptide repeat - - - 0.00005332 52.0
WLSH3_k127_1705131_0 KH domain K07041 - - 1.069e-264 829.0
WLSH3_k127_1705131_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 361.0
WLSH3_k127_1705131_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 325.0
WLSH3_k127_1705131_3 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 295.0
WLSH3_k127_1705131_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
WLSH3_k127_1705131_5 Belongs to the 'phage' integrase family K04763 - - 0.00000000000000000000000001652 118.0
WLSH3_k127_1705131_6 PAS domain K02488 - 2.7.7.65 0.000000000000000000000193 104.0
WLSH3_k127_1705131_7 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000006397 98.0
WLSH3_k127_1705131_8 - - - - 0.00000000000000001275 97.0
WLSH3_k127_1761098_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 463.0
WLSH3_k127_1761098_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000002724 230.0
WLSH3_k127_1761098_2 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000000000006646 102.0
WLSH3_k127_1761098_3 COG0784 FOG CheY-like receiver - - - 0.00000002735 61.0
WLSH3_k127_1821052_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 522.0
WLSH3_k127_1821052_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 445.0
WLSH3_k127_1821052_10 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001964 130.0
WLSH3_k127_1821052_11 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000008285 130.0
WLSH3_k127_1821052_12 - - - - 0.000000000000000000000000000003405 132.0
WLSH3_k127_1821052_13 - - - - 0.000000000000287 73.0
WLSH3_k127_1821052_14 Major Facilitator Superfamily - - - 0.000000000002159 79.0
WLSH3_k127_1821052_15 Protein of unknown function DUF131 - - - 0.0000001511 60.0
WLSH3_k127_1821052_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007497 286.0
WLSH3_k127_1821052_3 Pantothenate synthetase K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000002352 259.0
WLSH3_k127_1821052_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000009482 252.0
WLSH3_k127_1821052_5 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
WLSH3_k127_1821052_6 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000001392 243.0
WLSH3_k127_1821052_7 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000001602 215.0
WLSH3_k127_1821052_8 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000005143 194.0
WLSH3_k127_1821052_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000002003 181.0
WLSH3_k127_1867045_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 433.0
WLSH3_k127_1867045_1 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
WLSH3_k127_1867045_10 COG0500 SAM-dependent methyltransferases - - - 0.00000000000002583 83.0
WLSH3_k127_1867045_11 - - - - 0.0000000000004569 73.0
WLSH3_k127_1867045_12 PFAM Radical SAM domain protein K22227 - - 0.00001698 54.0
WLSH3_k127_1867045_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000126 261.0
WLSH3_k127_1867045_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000005122 239.0
WLSH3_k127_1867045_4 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000001482 205.0
WLSH3_k127_1867045_5 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001031 181.0
WLSH3_k127_1867045_6 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000001204 128.0
WLSH3_k127_1867045_7 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000001215 131.0
WLSH3_k127_1867045_8 - - - - 0.0000000000000000000000008213 110.0
WLSH3_k127_1867045_9 NUDIX domain K03574 - 3.6.1.55 0.000000000000000000000001599 116.0
WLSH3_k127_1876883_0 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002632 273.0
WLSH3_k127_1876883_1 PFAM Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000866 262.0
WLSH3_k127_1876883_2 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000329 231.0
WLSH3_k127_1876883_3 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000000003423 231.0
WLSH3_k127_1876883_4 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000005349 207.0
WLSH3_k127_1876883_5 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000002442 200.0
WLSH3_k127_1876883_6 Phosphohydrolase K09163 - - 0.000000000000000000000000002134 118.0
WLSH3_k127_1876883_7 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000001326 89.0
WLSH3_k127_2105325_0 Heat shock 70 kDa protein K04043 - - 9.761e-265 828.0
WLSH3_k127_2105325_1 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 414.0
WLSH3_k127_2105325_10 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002355 269.0
WLSH3_k127_2105325_11 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000009037 239.0
WLSH3_k127_2105325_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000007951 237.0
WLSH3_k127_2105325_13 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000006006 227.0
WLSH3_k127_2105325_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000004985 223.0
WLSH3_k127_2105325_15 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000003347 214.0
WLSH3_k127_2105325_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000003349 198.0
WLSH3_k127_2105325_17 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000008384 200.0
WLSH3_k127_2105325_18 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000001511 145.0
WLSH3_k127_2105325_19 - - - - 0.00000000000000000000000000000005811 136.0
WLSH3_k127_2105325_2 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 385.0
WLSH3_k127_2105325_20 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.00000000000000000000000000001573 130.0
WLSH3_k127_2105325_21 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000004167 108.0
WLSH3_k127_2105325_3 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 385.0
WLSH3_k127_2105325_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 376.0
WLSH3_k127_2105325_5 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 351.0
WLSH3_k127_2105325_6 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 324.0
WLSH3_k127_2105325_7 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006917 316.0
WLSH3_k127_2105325_8 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 293.0
WLSH3_k127_2105325_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000004659 268.0
WLSH3_k127_2110140_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 7.617e-194 615.0
WLSH3_k127_2110140_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000007653 196.0
WLSH3_k127_2110140_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000005965 120.0
WLSH3_k127_2110140_3 Transcriptional regulator K11924 - - 0.0000000000002749 73.0
WLSH3_k127_2110140_4 Aminotransferase class-III K00823 - 2.6.1.19 0.00003745 46.0
WLSH3_k127_2191594_0 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 542.0
WLSH3_k127_2191594_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001914 269.0
WLSH3_k127_2191594_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000001058 92.0
WLSH3_k127_2191594_3 NAD NADP octopine nopaline K04940 - 1.5.1.28 0.000000000000000015 85.0
WLSH3_k127_21955_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000001663 170.0
WLSH3_k127_21955_1 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000007989 149.0
WLSH3_k127_21955_2 Participates in both transcription termination and antitermination K02600 - - 0.0001367 54.0
WLSH3_k127_2353007_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.693e-243 756.0
WLSH3_k127_2353007_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002934 255.0
WLSH3_k127_2353007_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000003717 146.0
WLSH3_k127_2392053_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 612.0
WLSH3_k127_2392053_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000001574 251.0
WLSH3_k127_2392053_2 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000001479 218.0
WLSH3_k127_2392053_3 Listeria-Bacteroides repeat domain (List_Bact_rpt) - - - 0.00000000000001125 88.0
WLSH3_k127_2397109_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.78e-316 982.0
WLSH3_k127_2397109_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 412.0
WLSH3_k127_2397109_2 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001265 289.0
WLSH3_k127_2397109_3 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000441 285.0
WLSH3_k127_2397109_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000003031 98.0
WLSH3_k127_2397109_5 - - - - 0.00000000000000000000153 103.0
WLSH3_k127_2397109_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000002558 96.0
WLSH3_k127_2515041_0 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 619.0
WLSH3_k127_2515041_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 402.0
WLSH3_k127_2515041_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001145 262.0
WLSH3_k127_2515041_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000211 92.0
WLSH3_k127_2515041_4 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000003969 86.0
WLSH3_k127_253585_0 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000004025 164.0
WLSH3_k127_253585_1 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000000000000000183 162.0
WLSH3_k127_253585_2 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000001648 137.0
WLSH3_k127_253585_3 OmpA family K02557,K03286 - - 0.0000000008048 67.0
WLSH3_k127_2538970_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 4.485e-262 822.0
WLSH3_k127_2538970_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 484.0
WLSH3_k127_2538970_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
WLSH3_k127_2538970_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009396 314.0
WLSH3_k127_2538970_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000002758 198.0
WLSH3_k127_2538970_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000004289 170.0
WLSH3_k127_2538970_6 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.000000000000000000000005079 109.0
WLSH3_k127_2538970_7 exosome subunit K07581 - - 0.0000000000000000004639 92.0
WLSH3_k127_2541658_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 502.0
WLSH3_k127_2541658_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 424.0
WLSH3_k127_2541658_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000001656 222.0
WLSH3_k127_2541658_3 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000003188 223.0
WLSH3_k127_2541658_4 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000005205 186.0
WLSH3_k127_2541658_5 - - - - 0.000000000000000000000000000000000000004543 159.0
WLSH3_k127_2541658_6 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000006391 149.0
WLSH3_k127_2541658_7 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000000007154 110.0
WLSH3_k127_2566373_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 596.0
WLSH3_k127_2566373_1 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 547.0
WLSH3_k127_2566373_10 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001853 287.0
WLSH3_k127_2566373_11 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000002491 258.0
WLSH3_k127_2566373_12 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000003949 236.0
WLSH3_k127_2566373_13 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000000003464 195.0
WLSH3_k127_2566373_14 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000000000007893 186.0
WLSH3_k127_2566373_15 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000000000002769 190.0
WLSH3_k127_2566373_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000001766 184.0
WLSH3_k127_2566373_17 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000000000001706 147.0
WLSH3_k127_2566373_18 MFS/sugar transport protein - - - 0.000000000000000000000000000000000002803 153.0
WLSH3_k127_2566373_19 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000002979 142.0
WLSH3_k127_2566373_2 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 538.0
WLSH3_k127_2566373_20 Pfam:KaiC - - - 0.00000000000000000000000000000001745 139.0
WLSH3_k127_2566373_21 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000001923 128.0
WLSH3_k127_2566373_22 KaiC - - - 0.000000000000000000000000006299 121.0
WLSH3_k127_2566373_23 helix_turn_helix ASNC type K06154 - - 0.0000000000000000000000002577 109.0
WLSH3_k127_2566373_24 PFAM CBS domain containing protein - - - 0.00000000000000000001531 96.0
WLSH3_k127_2566373_25 Protein of unknown function (DUF835) - - - 0.00000000000209 82.0
WLSH3_k127_2566373_26 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00005936 47.0
WLSH3_k127_2566373_27 EamA-like transporter family K08978 - - 0.0007674 51.0
WLSH3_k127_2566373_3 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 510.0
WLSH3_k127_2566373_4 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 501.0
WLSH3_k127_2566373_5 Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 437.0
WLSH3_k127_2566373_6 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 384.0
WLSH3_k127_2566373_7 PFAM response regulator receiver K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 361.0
WLSH3_k127_2566373_8 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 311.0
WLSH3_k127_2566373_9 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 293.0
WLSH3_k127_261076_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 316.0
WLSH3_k127_261076_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000004068 270.0
WLSH3_k127_261076_10 FHA domain - - - 0.0000009457 60.0
WLSH3_k127_261076_2 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007773 260.0
WLSH3_k127_261076_3 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000001818 241.0
WLSH3_k127_261076_4 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000001846 215.0
WLSH3_k127_261076_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000194 212.0
WLSH3_k127_261076_6 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000003058 192.0
WLSH3_k127_261076_7 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000000000000000006556 174.0
WLSH3_k127_261076_8 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000007928 117.0
WLSH3_k127_2624271_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000007667 246.0
WLSH3_k127_2624271_1 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000008271 185.0
WLSH3_k127_2625464_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 488.0
WLSH3_k127_2653423_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006683 258.0
WLSH3_k127_2653423_1 - - - - 0.0000000000000000000000000000000000000000000000001458 183.0
WLSH3_k127_2653423_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000003251 117.0
WLSH3_k127_2653423_3 membrane - - - 0.00005061 52.0
WLSH3_k127_2708069_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1052.0
WLSH3_k127_2708069_1 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 302.0
WLSH3_k127_2708069_2 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000492 263.0
WLSH3_k127_2708069_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000001384 207.0
WLSH3_k127_2708069_4 Pfam:DUF59 - - - 0.00000000000000001196 85.0
WLSH3_k127_2729757_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 480.0
WLSH3_k127_2729757_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 478.0
WLSH3_k127_2729757_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002128 286.0
WLSH3_k127_2729757_3 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000006147 218.0
WLSH3_k127_2729757_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003656 192.0
WLSH3_k127_2729757_5 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000004336 100.0
WLSH3_k127_2729757_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000005172 77.0
WLSH3_k127_2729757_7 Major facilitator superfamily - - - 0.00001423 57.0
WLSH3_k127_2776326_0 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000429 261.0
WLSH3_k127_2776326_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000007955 133.0
WLSH3_k127_2776326_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000003436 104.0
WLSH3_k127_2785029_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008671 520.0
WLSH3_k127_2785029_1 HisG, C-terminal domain K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000009077 267.0
WLSH3_k127_2785029_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000003831 127.0
WLSH3_k127_2785029_3 Response regulator receiver domain - - - 0.000000000000000003423 91.0
WLSH3_k127_2785029_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000462 79.0
WLSH3_k127_2785029_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000001661 78.0
WLSH3_k127_2785029_6 but it may be involved in stabilization of the trimeric complex - - - 0.0000000001759 63.0
WLSH3_k127_280197_0 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 352.0
WLSH3_k127_280197_1 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 346.0
WLSH3_k127_280197_10 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000002571 174.0
WLSH3_k127_280197_11 PHP-associated - - - 0.0000000000000000000000000000000001373 140.0
WLSH3_k127_280197_12 PIN domain of ribonuclease K07060 GO:0000469,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0030490,GO:0030684,GO:0030688,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1990904 - 0.00000000000000000000000002125 114.0
WLSH3_k127_280197_13 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000001716 111.0
WLSH3_k127_280197_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000007266 89.0
WLSH3_k127_280197_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000006759 85.0
WLSH3_k127_280197_2 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 307.0
WLSH3_k127_280197_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 302.0
WLSH3_k127_280197_4 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005005 271.0
WLSH3_k127_280197_5 ABC-type dipeptide oligopeptide nickel transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003658 269.0
WLSH3_k127_280197_6 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000156 238.0
WLSH3_k127_280197_7 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000249 239.0
WLSH3_k127_280197_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000009078 217.0
WLSH3_k127_280197_9 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000000002161 196.0
WLSH3_k127_2854838_0 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000008057 173.0
WLSH3_k127_2854838_1 cytochrome c biogenesis protein, transmembrane region K06196 - - 0.0000002994 62.0
WLSH3_k127_2854838_2 PhoU domain - - - 0.0000893 47.0
WLSH3_k127_2956864_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 317.0
WLSH3_k127_2956864_1 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 297.0
WLSH3_k127_3035570_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 312.0
WLSH3_k127_3035570_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000002437 67.0
WLSH3_k127_3035664_0 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 515.0
WLSH3_k127_3035664_1 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 357.0
WLSH3_k127_3035664_10 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001588 258.0
WLSH3_k127_3035664_11 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001078 247.0
WLSH3_k127_3035664_12 ATP-binding protein K16786 - - 0.00000000000000000000000000000000000000000000000000000000000000003655 233.0
WLSH3_k127_3035664_13 Radical SAM domain protein K09711 - - 0.0000000000000000000000000000000000000000000000000000000001246 215.0
WLSH3_k127_3035664_14 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000002152 174.0
WLSH3_k127_3035664_15 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000007779 152.0
WLSH3_k127_3035664_16 OmpA family - - - 0.000000000000000000000000000001569 139.0
WLSH3_k127_3035664_17 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000001208 115.0
WLSH3_k127_3035664_18 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000003023 83.0
WLSH3_k127_3035664_19 PFAM PKD domain containing protein - - - 0.0000000002283 73.0
WLSH3_k127_3035664_2 Family 5 K02035,K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 370.0
WLSH3_k127_3035664_20 - - - - 0.0003691 51.0
WLSH3_k127_3035664_21 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.000455 49.0
WLSH3_k127_3035664_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 340.0
WLSH3_k127_3035664_4 Rad51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 327.0
WLSH3_k127_3035664_5 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 324.0
WLSH3_k127_3035664_6 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 311.0
WLSH3_k127_3035664_7 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 310.0
WLSH3_k127_3035664_8 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 306.0
WLSH3_k127_3035664_9 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004662 284.0
WLSH3_k127_3279078_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 495.0
WLSH3_k127_3279078_1 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 417.0
WLSH3_k127_3279078_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.0000000000000000000000000000000000000000000000001896 189.0
WLSH3_k127_3279078_3 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000008885 157.0
WLSH3_k127_3279078_4 - - - - 0.0000000000006781 78.0
WLSH3_k127_3279078_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000006781 78.0
WLSH3_k127_3330378_0 helicase superfamily c-terminal domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 527.0
WLSH3_k127_3330378_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 407.0
WLSH3_k127_3330378_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000000000876 83.0
WLSH3_k127_3333410_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 1.173e-200 635.0
WLSH3_k127_3333410_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
WLSH3_k127_3333410_2 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0000000000000000000000000000001248 143.0
WLSH3_k127_3366462_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 516.0
WLSH3_k127_3366462_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 475.0
WLSH3_k127_3366462_10 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00002435 51.0
WLSH3_k127_3366462_2 PFAM AIR synthase related protein K07123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001347 287.0
WLSH3_k127_3366462_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004414 258.0
WLSH3_k127_3366462_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000005735 260.0
WLSH3_k127_3366462_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000007153 243.0
WLSH3_k127_3366462_6 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
WLSH3_k127_3366462_7 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000002183 231.0
WLSH3_k127_3366462_8 - K00960 - 2.7.7.6 0.0000000000000006159 78.0
WLSH3_k127_3366462_9 transcriptional regulators - - - 0.00000000008601 69.0
WLSH3_k127_3397550_0 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 351.0
WLSH3_k127_3397550_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000003878 130.0
WLSH3_k127_3397550_2 CheC-like family K03410 - - 0.0000000000000000000000000000001272 131.0
WLSH3_k127_3478517_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000349 172.0
WLSH3_k127_3478517_1 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.00000000000000001245 95.0
WLSH3_k127_3499708_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1031.0
WLSH3_k127_3499708_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 595.0
WLSH3_k127_3499708_10 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000002801 94.0
WLSH3_k127_3499708_11 - - - - 0.000000001412 61.0
WLSH3_k127_3499708_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003297 248.0
WLSH3_k127_3499708_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002434 247.0
WLSH3_k127_3499708_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000002428 193.0
WLSH3_k127_3499708_5 nitroreductase - - - 0.0000000000000000000000000000000000000000000000001982 181.0
WLSH3_k127_3499708_6 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000001464 171.0
WLSH3_k127_3499708_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000001971 144.0
WLSH3_k127_3499708_8 DMT(Drug metabolite transporter) superfamily permease - - - 0.0000000000000000000000000005285 125.0
WLSH3_k127_3499708_9 Protein of unknown function (DUF1616) - - - 0.00000000000000000000003345 107.0
WLSH3_k127_3535485_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 472.0
WLSH3_k127_3535485_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 390.0
WLSH3_k127_3535485_2 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000004317 244.0
WLSH3_k127_3535485_3 Elongator protein 3 MiaB NifB - - - 0.000000000004507 72.0
WLSH3_k127_3536481_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 352.0
WLSH3_k127_3536481_1 TIGRFAM phosphate ABC transporter K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 304.0
WLSH3_k127_3536481_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008983 286.0
WLSH3_k127_3536481_3 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002748 258.0
WLSH3_k127_3536481_4 Phosphate uptake regulator, PhoU - - - 0.0000000000000000000000000000000000000000000000000000002385 205.0
WLSH3_k127_3536481_5 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000007209 191.0
WLSH3_k127_3536481_6 Transcriptional regulators - - - 0.0000647 52.0
WLSH3_k127_355369_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 519.0
WLSH3_k127_355369_1 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000004451 128.0
WLSH3_k127_355369_2 protein conserved in archaea - - - 0.0000000000000000002145 94.0
WLSH3_k127_355369_3 - - - - 0.0000000002361 63.0
WLSH3_k127_365012_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 414.0
WLSH3_k127_365012_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 324.0
WLSH3_k127_365012_2 Tetratricopeptide repeat K07452 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 311.0
WLSH3_k127_365012_3 - - - - 0.00000000000000000000000000000000000000000000000000001895 201.0
WLSH3_k127_365012_4 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000003251 171.0
WLSH3_k127_3665329_0 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 392.0
WLSH3_k127_3665329_1 Proton-conducting membrane transporter K05565,K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000007143 244.0
WLSH3_k127_3665329_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0002006 48.0
WLSH3_k127_3742591_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 599.0
WLSH3_k127_3742591_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 531.0
WLSH3_k127_3742591_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 389.0
WLSH3_k127_3742591_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 330.0
WLSH3_k127_3742591_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 321.0
WLSH3_k127_3742591_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 314.0
WLSH3_k127_3742591_6 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 271.0
WLSH3_k127_3742591_7 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000009659 161.0
WLSH3_k127_3742591_8 PAS domain K02488 - 2.7.7.65 0.0000000000003359 82.0
WLSH3_k127_3746892_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.05e-254 799.0
WLSH3_k127_3746892_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.62e-202 642.0
WLSH3_k127_3746892_10 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000001448 184.0
WLSH3_k127_3746892_11 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000006538 172.0
WLSH3_k127_3746892_12 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000009378 161.0
WLSH3_k127_3746892_13 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.000000000000000000000000722 123.0
WLSH3_k127_3746892_14 PFAM Formiminotransferase-cyclodeaminase - - - 0.000000000000000000487 96.0
WLSH3_k127_3746892_15 KEOPS complex Cgi121-like subunit K09119 - - 0.000000000005082 74.0
WLSH3_k127_3746892_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 620.0
WLSH3_k127_3746892_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 587.0
WLSH3_k127_3746892_4 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 451.0
WLSH3_k127_3746892_5 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 346.0
WLSH3_k127_3746892_6 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 351.0
WLSH3_k127_3746892_7 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 253.0
WLSH3_k127_3746892_8 PFAM Circadian clock protein KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
WLSH3_k127_3746892_9 Nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000004174 199.0
WLSH3_k127_3773394_0 CO-methylating acetyl-CoA synthase activity K00193,K14138 - 2.3.1.169 7.177e-228 756.0
WLSH3_k127_3773394_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 606.0
WLSH3_k127_3773394_10 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000005555 230.0
WLSH3_k127_3773394_11 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000006455 220.0
WLSH3_k127_3773394_12 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000003163 192.0
WLSH3_k127_3773394_13 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000005384 124.0
WLSH3_k127_3773394_14 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000006443 120.0
WLSH3_k127_3773394_15 PFAM Forkhead-associated protein - - - 0.00000000000000000000000006826 119.0
WLSH3_k127_3773394_16 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000006513 111.0
WLSH3_k127_3773394_17 Clostripain family - - - 0.000000000000000000005268 106.0
WLSH3_k127_3773394_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000002646 80.0
WLSH3_k127_3773394_19 COG1138 Cytochrome c biogenesis factor K02198 - - 0.0000002546 62.0
WLSH3_k127_3773394_2 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 487.0
WLSH3_k127_3773394_20 PFAM amino acid-binding ACT domain protein - - - 0.000004427 54.0
WLSH3_k127_3773394_3 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 422.0
WLSH3_k127_3773394_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 390.0
WLSH3_k127_3773394_5 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 316.0
WLSH3_k127_3773394_6 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 299.0
WLSH3_k127_3773394_7 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 308.0
WLSH3_k127_3773394_8 CO dehydrogenase acetyl-CoA synthase K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004965 274.0
WLSH3_k127_3773394_9 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000001786 235.0
WLSH3_k127_3799828_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 486.0
WLSH3_k127_3799828_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 332.0
WLSH3_k127_3799828_10 Protein of unknown function (DUF3198) - - - 0.0001335 49.0
WLSH3_k127_3799828_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000000000000002043 245.0
WLSH3_k127_3799828_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000005966 168.0
WLSH3_k127_3799828_4 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000002026 169.0
WLSH3_k127_3799828_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000006281 102.0
WLSH3_k127_3799828_6 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.0000000004971 62.0
WLSH3_k127_3799828_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000002931 52.0
WLSH3_k127_3799828_8 membrane-associated protein domain - - - 0.000002925 57.0
WLSH3_k127_3799828_9 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00007475 49.0
WLSH3_k127_3835499_0 Glutamate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 614.0
WLSH3_k127_3835499_1 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 528.0
WLSH3_k127_3835499_10 OsmC-like protein - - - 0.00000000000000000000000000000000058 136.0
WLSH3_k127_3835499_11 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000003075 131.0
WLSH3_k127_3835499_12 Major Facilitator - - - 0.00000000000000000000000000009115 130.0
WLSH3_k127_3835499_13 - - - - 0.0000000001754 65.0
WLSH3_k127_3835499_2 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 455.0
WLSH3_k127_3835499_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 436.0
WLSH3_k127_3835499_4 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 386.0
WLSH3_k127_3835499_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 354.0
WLSH3_k127_3835499_6 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005093 229.0
WLSH3_k127_3835499_7 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000001093 231.0
WLSH3_k127_3835499_8 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000001969 211.0
WLSH3_k127_3835499_9 GXGXG motif - - - 0.0000000000000000000000000000000000000000000000685 179.0
WLSH3_k127_3843375_0 Subtilase family K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000005783 261.0
WLSH3_k127_3843375_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000002604 183.0
WLSH3_k127_3843375_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000001513 71.0
WLSH3_k127_3843375_3 RHS Repeat - - - 0.0000009255 59.0
WLSH3_k127_3843375_4 exodeoxyribonuclease I activity - - - 0.0006832 51.0
WLSH3_k127_3851553_0 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 2.664e-270 837.0
WLSH3_k127_3851553_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000008957 255.0
WLSH3_k127_3854159_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 494.0
WLSH3_k127_3854159_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004983 276.0
WLSH3_k127_3854159_2 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007867 273.0
WLSH3_k127_3854159_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000008368 244.0
WLSH3_k127_3854159_4 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001217 200.0
WLSH3_k127_3854159_5 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000004497 178.0
WLSH3_k127_3854159_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000005608 150.0
WLSH3_k127_3854159_7 Lamin Tail Domain - - - 0.000000000000000000000000000000000004939 155.0
WLSH3_k127_3854159_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000001939 79.0
WLSH3_k127_3854159_9 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.00000000000000441 78.0
WLSH3_k127_3858494_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 393.0
WLSH3_k127_3858494_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 335.0
WLSH3_k127_3858494_10 Rubrerythrin - - - 0.0000000000000000000000000000000005569 134.0
WLSH3_k127_3858494_11 PFAM CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000007057 99.0
WLSH3_k127_3858494_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000001099 81.0
WLSH3_k127_3858494_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 324.0
WLSH3_k127_3858494_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000185 267.0
WLSH3_k127_3858494_4 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002331 245.0
WLSH3_k127_3858494_5 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000624 175.0
WLSH3_k127_3858494_6 LysE type translocator - - - 0.00000000000000000000000000000000000000000009324 168.0
WLSH3_k127_3858494_7 Oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000005644 155.0
WLSH3_k127_3858494_8 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000000001441 147.0
WLSH3_k127_3858494_9 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.00000000000000000000000000000000001782 142.0
WLSH3_k127_3859902_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 427.0
WLSH3_k127_3859902_1 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 407.0
WLSH3_k127_3859902_10 exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000001277 195.0
WLSH3_k127_3859902_11 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000006938 188.0
WLSH3_k127_3859902_12 Saccharopine dehydrogenase K00290,K19064 - 1.4.1.18,1.5.1.7 0.000000000000000000000000000000000000002839 161.0
WLSH3_k127_3859902_13 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000000000000000000000000000000001095 155.0
WLSH3_k127_3859902_14 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000004879 159.0
WLSH3_k127_3859902_15 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000004487 159.0
WLSH3_k127_3859902_16 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000558 146.0
WLSH3_k127_3859902_17 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000000861 146.0
WLSH3_k127_3859902_18 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000003901 130.0
WLSH3_k127_3859902_19 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000005572 124.0
WLSH3_k127_3859902_2 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 373.0
WLSH3_k127_3859902_20 Rubredoxin - - - 0.000000000000000000000439 97.0
WLSH3_k127_3859902_21 Protein of unknown function (DUF1614) - - - 0.000000000000000000001076 104.0
WLSH3_k127_3859902_22 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000001367 97.0
WLSH3_k127_3859902_23 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000001764 94.0
WLSH3_k127_3859902_24 Small-conductance mechanosensitive channel - - - 0.000000000000000005298 92.0
WLSH3_k127_3859902_25 PFAM CBS domain - - - 0.0000000000000008338 83.0
WLSH3_k127_3859902_26 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.000000000000003777 75.0
WLSH3_k127_3859902_27 Major facilitator Superfamily - - - 0.000000000000004539 87.0
WLSH3_k127_3859902_28 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000001879 70.0
WLSH3_k127_3859902_29 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000003037 76.0
WLSH3_k127_3859902_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 378.0
WLSH3_k127_3859902_30 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.0000000001138 72.0
WLSH3_k127_3859902_31 Rubrerythrin - - - 0.00000001124 63.0
WLSH3_k127_3859902_32 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000001571 55.0
WLSH3_k127_3859902_33 Zn-finger in Ran binding protein and others - - - 0.0002769 49.0
WLSH3_k127_3859902_4 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 373.0
WLSH3_k127_3859902_5 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 354.0
WLSH3_k127_3859902_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 354.0
WLSH3_k127_3859902_7 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 305.0
WLSH3_k127_3859902_8 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 291.0
WLSH3_k127_3859902_9 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006593 248.0
WLSH3_k127_39116_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.077e-281 899.0
WLSH3_k127_39116_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 468.0
WLSH3_k127_39116_10 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000001818 103.0
WLSH3_k127_39116_11 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000001091 102.0
WLSH3_k127_39116_12 Peptidase_C39 like family - - - 0.0000000000000001118 90.0
WLSH3_k127_39116_13 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000007041 80.0
WLSH3_k127_39116_14 - - - - 0.000000000000004366 76.0
WLSH3_k127_39116_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 329.0
WLSH3_k127_39116_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 307.0
WLSH3_k127_39116_4 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 295.0
WLSH3_k127_39116_5 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001228 286.0
WLSH3_k127_39116_6 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 261.0
WLSH3_k127_39116_7 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000001893 152.0
WLSH3_k127_39116_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003436 109.0
WLSH3_k127_39116_9 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000006995 107.0
WLSH3_k127_3946496_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
WLSH3_k127_3946496_1 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000008322 179.0
WLSH3_k127_3946496_2 PAC2 family K06869 - - 0.000000000000001483 81.0
WLSH3_k127_408968_0 PFAM Mechanosensitive ion channel K16052 - - 0.00000000000000000001157 106.0
WLSH3_k127_408968_1 DDE_Tnp_1-associated - - - 0.00000000007224 71.0
WLSH3_k127_408968_2 CarboxypepD_reg-like domain - - - 0.0009392 49.0
WLSH3_k127_4184660_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 574.0
WLSH3_k127_4184660_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 494.0
WLSH3_k127_4184660_10 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005768 250.0
WLSH3_k127_4184660_11 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000002828 198.0
WLSH3_k127_4184660_12 PFAM DoxX family protein K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000002936 195.0
WLSH3_k127_4184660_13 B12 binding domain K14084 - - 0.00000000000000000000000000000000000000000000000000009432 194.0
WLSH3_k127_4184660_14 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000007298 186.0
WLSH3_k127_4184660_15 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000001496 161.0
WLSH3_k127_4184660_16 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000001407 158.0
WLSH3_k127_4184660_17 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000001044 155.0
WLSH3_k127_4184660_18 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000002394 151.0
WLSH3_k127_4184660_19 flavin reductase - - - 0.000000000000000000000000000000000000659 146.0
WLSH3_k127_4184660_2 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 405.0
WLSH3_k127_4184660_20 PFAM NIL domain - - - 0.00000000000000000000000000000005272 128.0
WLSH3_k127_4184660_21 nucleotide metabolic process - - - 0.000000000000000000199 97.0
WLSH3_k127_4184660_22 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0008150,GO:0009987,GO:0051301 - 0.000000000000002207 87.0
WLSH3_k127_4184660_3 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 327.0
WLSH3_k127_4184660_4 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 311.0
WLSH3_k127_4184660_5 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008133 295.0
WLSH3_k127_4184660_6 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006021 279.0
WLSH3_k127_4184660_7 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004658 272.0
WLSH3_k127_4184660_8 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000001276 271.0
WLSH3_k127_4184660_9 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000000003931 258.0
WLSH3_k127_4196138_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1110.0
WLSH3_k127_4196138_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1080.0
WLSH3_k127_4196138_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 338.0
WLSH3_k127_4196138_11 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004662 282.0
WLSH3_k127_4196138_12 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
WLSH3_k127_4196138_13 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000002246 229.0
WLSH3_k127_4196138_14 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23,1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000002575 232.0
WLSH3_k127_4196138_15 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000005122 230.0
WLSH3_k127_4196138_16 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000003618 222.0
WLSH3_k127_4196138_17 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000004065 213.0
WLSH3_k127_4196138_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000002972 216.0
WLSH3_k127_4196138_19 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000001007 207.0
WLSH3_k127_4196138_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.193e-271 851.0
WLSH3_k127_4196138_20 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000002496 198.0
WLSH3_k127_4196138_21 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000015 198.0
WLSH3_k127_4196138_22 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000002503 197.0
WLSH3_k127_4196138_23 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000002345 194.0
WLSH3_k127_4196138_24 - - - - 0.0000000000000000000000000000000000186 145.0
WLSH3_k127_4196138_25 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000009399 121.0
WLSH3_k127_4196138_26 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000005226 113.0
WLSH3_k127_4196138_27 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000002534 113.0
WLSH3_k127_4196138_28 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000001051 115.0
WLSH3_k127_4196138_29 hmm pf03415 K08587 - 3.4.22.8 0.0000000000000000000005209 110.0
WLSH3_k127_4196138_3 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 600.0
WLSH3_k127_4196138_30 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000005529 86.0
WLSH3_k127_4196138_31 - - - - 0.0000000000005654 78.0
WLSH3_k127_4196138_32 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000003366 65.0
WLSH3_k127_4196138_4 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 492.0
WLSH3_k127_4196138_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 452.0
WLSH3_k127_4196138_6 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 394.0
WLSH3_k127_4196138_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 409.0
WLSH3_k127_4196138_8 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 359.0
WLSH3_k127_4196138_9 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 354.0
WLSH3_k127_4217082_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 589.0
WLSH3_k127_4217082_1 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004095 540.0
WLSH3_k127_4217082_10 metal ion binding - - - 0.00000000000000000003649 96.0
WLSH3_k127_4217082_11 protein conserved in archaea K09723 - - 0.0000000000001346 79.0
WLSH3_k127_4217082_12 Belongs to the UPF0235 family K09131 - - 0.000000000003827 70.0
WLSH3_k127_4217082_13 Lrp/AsnC ligand binding domain - - - 0.0000001766 56.0
WLSH3_k127_4217082_2 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 436.0
WLSH3_k127_4217082_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 389.0
WLSH3_k127_4217082_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 336.0
WLSH3_k127_4217082_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001204 259.0
WLSH3_k127_4217082_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000002651 182.0
WLSH3_k127_4217082_7 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000001679 173.0
WLSH3_k127_4217082_8 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000007525 152.0
WLSH3_k127_4217082_9 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000000000000008897 140.0
WLSH3_k127_4242805_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1067.0
WLSH3_k127_4242805_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 395.0
WLSH3_k127_4242805_10 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000538 177.0
WLSH3_k127_4242805_11 - - - - 0.000000000006979 68.0
WLSH3_k127_4242805_2 ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 362.0
WLSH3_k127_4242805_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 363.0
WLSH3_k127_4242805_4 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 352.0
WLSH3_k127_4242805_5 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 347.0
WLSH3_k127_4242805_6 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 344.0
WLSH3_k127_4242805_7 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002856 279.0
WLSH3_k127_4242805_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
WLSH3_k127_4242805_9 PFAM Major Facilitator Superfamily K19576 - - 0.000000000000000000000000000000000000000000000000000006049 204.0
WLSH3_k127_4324073_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 514.0
WLSH3_k127_4324073_1 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000002388 97.0
WLSH3_k127_4324073_2 binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002773 85.0
WLSH3_k127_4324073_3 - - - - 0.0000000000000325 83.0
WLSH3_k127_4344518_0 acetyl-CoA hydrolase transferase - - - 2.244e-216 690.0
WLSH3_k127_4344518_1 Citrate transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 481.0
WLSH3_k127_4344518_10 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000004223 222.0
WLSH3_k127_4344518_11 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000004033 179.0
WLSH3_k127_4344518_12 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.00000000000000000000000000000000000005085 145.0
WLSH3_k127_4344518_13 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000000000000000000000000003646 135.0
WLSH3_k127_4344518_14 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000002323 115.0
WLSH3_k127_4344518_15 NifU-like N terminal domain K04488 - - 0.0000000000000000000000016 113.0
WLSH3_k127_4344518_16 Protein of unknown function DUF134 - - - 0.0000000000000000000007736 98.0
WLSH3_k127_4344518_17 DsrE/DsrF-like family - - - 0.0000000000000000004409 94.0
WLSH3_k127_4344518_18 Aids in the defense against invading fungal pathogens by degrading their cell wall chitosan K01233 - 3.2.1.132 0.0000000000000002717 91.0
WLSH3_k127_4344518_19 Protein of unknown function DUF134 - - - 0.00000000239 62.0
WLSH3_k127_4344518_2 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 431.0
WLSH3_k127_4344518_21 Bacterio-opsin activator HTH domain-containing protein - - - 0.000001165 58.0
WLSH3_k127_4344518_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 420.0
WLSH3_k127_4344518_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 364.0
WLSH3_k127_4344518_5 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 371.0
WLSH3_k127_4344518_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
WLSH3_k127_4344518_7 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 280.0
WLSH3_k127_4344518_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000168 274.0
WLSH3_k127_4344518_9 CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008053 276.0
WLSH3_k127_4515015_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 366.0
WLSH3_k127_4515015_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 303.0
WLSH3_k127_4515015_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001249 240.0
WLSH3_k127_4515015_3 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000001642 178.0
WLSH3_k127_4515015_4 Cache domain - - - 0.000000000000000000000000000000000000000000001202 188.0
WLSH3_k127_4515015_5 Chemotaxis protein cheW K03408 - - 0.0000000000000000000000000000000006907 135.0
WLSH3_k127_4515015_6 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000004636 131.0
WLSH3_k127_4515015_7 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000009016 124.0
WLSH3_k127_4515015_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 1.1.1.86 0.0000000000000007035 78.0
WLSH3_k127_4561382_0 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 567.0
WLSH3_k127_4561382_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 379.0
WLSH3_k127_4561382_10 myo-inosose-2 dehydratase activity K10709 - - 0.0000171 48.0
WLSH3_k127_4561382_11 COG1335 Amidases related to nicotinamidase - - - 0.00002201 54.0
WLSH3_k127_4561382_12 Serine threonine-protein kinase K04424 - 2.7.11.25 0.0009201 45.0
WLSH3_k127_4561382_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 365.0
WLSH3_k127_4561382_3 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000007068 258.0
WLSH3_k127_4561382_4 Flavodoxin - - - 0.00000000000000000000000000000000000000001623 157.0
WLSH3_k127_4561382_5 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000605 134.0
WLSH3_k127_4561382_6 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000004004 108.0
WLSH3_k127_4561382_7 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000005522 101.0
WLSH3_k127_4561382_8 acetyltransferase - - - 0.000000000000001386 88.0
WLSH3_k127_4561382_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000001188 70.0
WLSH3_k127_4562307_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000000000000000000000000000472 157.0
WLSH3_k127_4570008_0 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 370.0
WLSH3_k127_4570008_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
WLSH3_k127_4570008_2 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001066 261.0
WLSH3_k127_4570008_3 PFAM ABC transporter K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000003564 246.0
WLSH3_k127_4570008_4 ATP-binding protein K16786 - - 0.00000000000000000000000000000000000000000000000000000000000000001428 234.0
WLSH3_k127_4570008_5 ABC-type cobalt transport system, permease K16785 - - 0.0000000000000000000000000000000000000000002896 168.0
WLSH3_k127_4570008_6 ECF-type riboflavin transporter, S component - - - 0.000000000000000000000000000002451 128.0
WLSH3_k127_4641753_0 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 369.0
WLSH3_k127_4641753_1 aldo keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 346.0
WLSH3_k127_4758131_0 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000004458 172.0
WLSH3_k127_4758131_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000002674 164.0
WLSH3_k127_4758131_2 PRC-barrel domain - - - 0.00000000000000001685 87.0
WLSH3_k127_4758131_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.00000000000000008817 81.0
WLSH3_k127_4758131_4 Thioredoxin K03671 - - 0.000000000003843 70.0
WLSH3_k127_480473_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 461.0
WLSH3_k127_480473_1 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 354.0
WLSH3_k127_480473_10 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.0000000000000000000000000000000003805 152.0
WLSH3_k127_480473_11 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000004839 139.0
WLSH3_k127_480473_12 Methylase involved in ubiquinone menaquinone K07755 - 2.1.1.137 0.000000000000007198 83.0
WLSH3_k127_480473_13 serine-type endopeptidase activity - - - 0.0000000005198 74.0
WLSH3_k127_480473_14 diguanylate cyclase - - - 0.00000002363 67.0
WLSH3_k127_480473_15 Protein of unknown function (DUF1616) - - - 0.000001015 59.0
WLSH3_k127_480473_16 efflux transmembrane transporter activity K02004 - - 0.00002113 58.0
WLSH3_k127_480473_17 MacB-like periplasmic core domain K02004 - - 0.00004841 57.0
WLSH3_k127_480473_18 ABC transporter K02003,K02004 - - 0.00005524 55.0
WLSH3_k127_480473_19 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0001615 51.0
WLSH3_k127_480473_2 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 316.0
WLSH3_k127_480473_3 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003184 248.0
WLSH3_k127_480473_4 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000248 201.0
WLSH3_k127_480473_5 TIGRFAM PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000002073 205.0
WLSH3_k127_480473_6 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000005516 199.0
WLSH3_k127_480473_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000005328 192.0
WLSH3_k127_480473_8 Desulfoferrodoxin K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000001285 179.0
WLSH3_k127_480473_9 B12 binding domain K14084 - - 0.000000000000000000000000000000000000000002863 166.0
WLSH3_k127_4848867_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 359.0
WLSH3_k127_4848867_1 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
WLSH3_k127_4848867_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000001578 194.0
WLSH3_k127_4848867_3 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000004809 141.0
WLSH3_k127_493264_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 501.0
WLSH3_k127_493264_1 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 498.0
WLSH3_k127_493264_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 495.0
WLSH3_k127_493264_3 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000034 286.0
WLSH3_k127_493264_4 Helix-turn-helix XRE-family like proteins K07731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002276 271.0
WLSH3_k127_493264_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000003513 163.0
WLSH3_k127_5031823_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002058 297.0
WLSH3_k127_5031823_1 CHAT domain - - - 0.000000000000000000000000000000000000000000008041 183.0
WLSH3_k127_5031823_2 tripeptidyl-peptidase activity - - - 0.000000000000000001037 102.0
WLSH3_k127_5031823_3 Belongs to the peptidase S8 family - - - 0.0000000000009554 78.0
WLSH3_k127_5031823_4 amine dehydrogenase activity - - - 0.0000001924 65.0
WLSH3_k127_5039475_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 365.0
WLSH3_k127_5039475_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000259 164.0
WLSH3_k127_5039475_2 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.0000000000001162 72.0
WLSH3_k127_5039475_3 Fe-S oxidoreductase - - - 0.00000001074 66.0
WLSH3_k127_5039475_4 Major facilitator superfamily K08222 - - 0.00000004852 65.0
WLSH3_k127_5043004_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 436.0
WLSH3_k127_5043004_1 UDP binding domain K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000009076 265.0
WLSH3_k127_5043004_2 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000001051 147.0
WLSH3_k127_5043004_3 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.000000000000000000001589 97.0
WLSH3_k127_5043004_4 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000001898 78.0
WLSH3_k127_5115063_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000034 216.0
WLSH3_k127_5115063_1 AhpC/TSA family K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000002575 179.0
WLSH3_k127_5115063_2 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.000000000000000000000000000000000000001244 160.0
WLSH3_k127_5115063_3 Tetratricopeptide repeat - - - 0.0000000000000000000002589 114.0
WLSH3_k127_5115063_4 Transcriptional regulator K07730 - - 0.000000000000000001033 96.0
WLSH3_k127_5115063_5 - - - - 0.0000000000000006295 92.0
WLSH3_k127_5115063_6 ABC transporter related K02013 - 3.6.3.34 0.00004089 48.0
WLSH3_k127_5121566_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.781e-257 802.0
WLSH3_k127_5121566_1 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 312.0
WLSH3_k127_5121566_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 310.0
WLSH3_k127_5121566_3 PFAM Methyltransferase domain - - - 0.000000000001813 79.0
WLSH3_k127_5193510_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 404.0
WLSH3_k127_5193510_1 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001137 286.0
WLSH3_k127_5193510_10 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000004166 112.0
WLSH3_k127_5193510_11 4Fe-4S dicluster domain - - - 0.000000000000000004677 87.0
WLSH3_k127_5193510_12 ABC-2 family transporter protein K01992 - - 0.00000000000000005526 95.0
WLSH3_k127_5193510_13 protein involved in the oxidation of intracellular sulfur K07236 - - 0.0000000000000002096 83.0
WLSH3_k127_5193510_14 - K21029 - 2.7.7.80 0.00002823 53.0
WLSH3_k127_5193510_2 Patch-forming domain C2 of tRNA-guanine transglycosylase K07557 GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001293 296.0
WLSH3_k127_5193510_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000000023 200.0
WLSH3_k127_5193510_4 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000001113 168.0
WLSH3_k127_5193510_5 AAA domain - - - 0.000000000000000000000000000000000000000000005226 169.0
WLSH3_k127_5193510_6 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000575 166.0
WLSH3_k127_5193510_7 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000001678 130.0
WLSH3_k127_5193510_8 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000008242 116.0
WLSH3_k127_5193510_9 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000015 115.0
WLSH3_k127_5349083_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 586.0
WLSH3_k127_5349083_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 529.0
WLSH3_k127_5349083_10 Flavodoxin domain - - - 0.0000000001068 69.0
WLSH3_k127_5349083_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009507 278.0
WLSH3_k127_5349083_3 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000007812 193.0
WLSH3_k127_5349083_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000001767 193.0
WLSH3_k127_5349083_5 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000001187 150.0
WLSH3_k127_5349083_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000001831 98.0
WLSH3_k127_5349083_7 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000007155 90.0
WLSH3_k127_5349083_8 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000008188 86.0
WLSH3_k127_5349083_9 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000002416 74.0
WLSH3_k127_5400701_0 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 352.0
WLSH3_k127_5400701_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 341.0
WLSH3_k127_5400701_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000001445 243.0
WLSH3_k127_5400701_3 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000000000000000000001233 202.0
WLSH3_k127_5400701_4 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.0000000000000000000000000000000000003238 154.0
WLSH3_k127_5400701_5 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000004715 148.0
WLSH3_k127_5400701_6 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000000000000000000001391 110.0
WLSH3_k127_5400701_7 TIGRFAM small GTP-binding protein domain - - - 0.000000000000000000001534 104.0
WLSH3_k127_5400701_8 OmpA family - - - 0.00000000004401 71.0
WLSH3_k127_5468764_0 CobW/HypB/UreG, nucleotide-binding domain - - - 9.942e-194 618.0
WLSH3_k127_5468764_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 570.0
WLSH3_k127_5468764_10 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000001307 187.0
WLSH3_k127_5468764_12 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000001463 180.0
WLSH3_k127_5468764_13 4Fe-4S dicluster domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000001746 166.0
WLSH3_k127_5468764_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000000003424 165.0
WLSH3_k127_5468764_15 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000007456 128.0
WLSH3_k127_5468764_16 - - - - 0.0000000000000000000004586 100.0
WLSH3_k127_5468764_17 transcriptional regulators - - - 0.00000000000000156 81.0
WLSH3_k127_5468764_2 COGs COG1680 Beta-lactamase class C and other penicillin binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 391.0
WLSH3_k127_5468764_3 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 389.0
WLSH3_k127_5468764_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 313.0
WLSH3_k127_5468764_5 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001536 269.0
WLSH3_k127_5468764_6 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000001067 253.0
WLSH3_k127_5468764_7 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002497 244.0
WLSH3_k127_5468764_8 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000002195 227.0
WLSH3_k127_5468764_9 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000002803 181.0
WLSH3_k127_5469709_0 ABC transporter K00400,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 364.0
WLSH3_k127_5469709_1 Peptidase family S51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 326.0
WLSH3_k127_5469709_10 Fic/DOC family - - - 0.00000000000000000000000000000000001441 147.0
WLSH3_k127_5469709_11 Cobalt transport protein K16785 - - 0.00000000000000000000000000000000002251 149.0
WLSH3_k127_5469709_12 Flavodoxin - - - 0.000000000000000000000000000000002563 136.0
WLSH3_k127_5469709_14 - - - - 0.00000000000000000001015 99.0
WLSH3_k127_5469709_15 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000001168 93.0
WLSH3_k127_5469709_16 PFAM PKD domain containing protein K02016,K16925 - - 0.000000000000003148 90.0
WLSH3_k127_5469709_17 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.00000000000002803 81.0
WLSH3_k127_5469709_18 - - - - 0.0000000008817 66.0
WLSH3_k127_5469709_19 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00001507 58.0
WLSH3_k127_5469709_2 COG1064 Zn-dependent alcohol K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 297.0
WLSH3_k127_5469709_20 transcriptional - - - 0.0001027 53.0
WLSH3_k127_5469709_21 axonal fasciculation K06491 GO:0000003,GO:0000139,GO:0000165,GO:0000902,GO:0000904,GO:0001654,GO:0001746,GO:0001928,GO:0002009,GO:0002165,GO:0002237,GO:0002376,GO:0003006,GO:0003008,GO:0003674,GO:0005085,GO:0005088,GO:0005102,GO:0005104,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0005911,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0006950,GO:0006952,GO:0006955,GO:0007154,GO:0007155,GO:0007156,GO:0007158,GO:0007165,GO:0007166,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007413,GO:0007417,GO:0007420,GO:0007423,GO:0007424,GO:0007444,GO:0007483,GO:0007484,GO:0007485,GO:0007528,GO:0007548,GO:0007552,GO:0007560,GO:0007568,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007614,GO:0007635,GO:0008037,GO:0008038,GO:0008045,GO:0008092,GO:0008150,GO:0008152,GO:0008284,GO:0008306,GO:0008355,GO:0008360,GO:0008582,GO:0009410,GO:0009605,GO:0009607,GO:0009611,GO:0009617,GO:0009636,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010288,GO:0010646,GO:0010647,GO:0010648,GO:0010721,GO:0010941,GO:0012505,GO:0014012,GO:0014041,GO:0014043,GO:0014070,GO:0014823,GO:0016020,GO:0016021,GO:0016043,GO:0016202,GO:0016310,GO:0016319,GO:0016338,GO:0016604,GO:0017016,GO:0017157,GO:0019221,GO:0019538,GO:0019899,GO:0019902,GO:0019904,GO:0021536,GO:0021794,GO:0022008,GO:0022414,GO:0022603,GO:0022604,GO:0022610,GO:0023014,GO:0023051,GO:0023052,GO:0023056,GO:0023057,GO:0030030,GO:0030054,GO:0030154,GO:0030182,GO:0030275,GO:0030424,GO:0030426,GO:0030427,GO:0030534,GO:0030539,GO:0030900,GO:0031090,GO:0031099,GO:0031100,GO:0031102,GO:0031103,GO:0031175,GO:0031224,GO:0031267,GO:0031594,GO:0031644,GO:0031974,GO:0031981,GO:0031984,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0033267,GO:0033554,GO:0033555,GO:0034097,GO:0034109,GO:0034341,GO:0035112,GO:0035126,GO:0035150,GO:0035151,GO:0035152,GO:0035158,GO:0035159,GO:0035215,GO:0035239,GO:0035295,GO:0035296,GO:0035556,GO:0036062,GO:0036211,GO:0036477,GO:0040008,GO:0040011,GO:0042048,GO:0042058,GO:0042059,GO:0042127,GO:0042220,GO:0042221,GO:0042330,GO:0042493,GO:0042734,GO:0042802,GO:0042995,GO:0043005,GO:0043025,GO:0043170,GO:0043195,GO:0043207,GO:0043209,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043279,GO:0043412,GO:0043679,GO:0044057,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044431,GO:0044444,GO:0044446,GO:0044451,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045087,GO:0045202,GO:0045211,GO:0045471,GO:0045595,GO:0045596,GO:0045664,GO:0045665,GO:0045844,GO:0045927,GO:0046620,GO:0046622,GO:0046661,GO:0046677,GO:0048149,GO:0048167,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048563,GO:0048569,GO:0048583,GO:0048584,GO:0048585,GO:0048592,GO:0048608,GO:0048634,GO:0048636,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048678,GO:0048699,GO:0048707,GO:0048729,GO:0048731,GO:0048786,GO:0048803,GO:0048805,GO:0048806,GO:0048808,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050767,GO:0050768,GO:0050789,GO:0050793,GO:0050794,GO:0050803,GO:0050804,GO:0050807,GO:0050808,GO:0050848,GO:0050850,GO:0050877,GO:0050890,GO:0050896,GO:0051020,GO:0051046,GO:0051049,GO:0051093,GO:0051094,GO:0051128,GO:0051239,GO:0051240,GO:0051241,GO:0051704,GO:0051707,GO:0051716,GO:0051930,GO:0051931,GO:0051960,GO:0051961,GO:0051963,GO:0055021,GO:0055023,GO:0055024,GO:0055025,GO:0055034,GO:0060043,GO:0060045,GO:0060284,GO:0060322,GO:0060333,GO:0060341,GO:0060359,GO:0060420,GO:0060421,GO:0060429,GO:0060541,GO:0060548,GO:0060562,GO:0060627,GO:0061174,GO:0061458,GO:0061564,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070851,GO:0070887,GO:0071216,GO:0071219,GO:0071241,GO:0071310,GO:0071345,GO:0071346,GO:0071679,GO:0071704,GO:0071840,GO:0071944,GO:0072347,GO:0072499,GO:0072553,GO:0090066,GO:0090596,GO:0090598,GO:0097060,GO:0097305,GO:0097458,GO:0097482,GO:0097485,GO:0098552,GO:0098588,GO:0098590,GO:0098609,GO:0098742,GO:0098772,GO:0098791,GO:0098793,GO:0098794,GO:0098975,GO:0099172,GO:0099177,GO:0099572,GO:0106020,GO:0106030,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1901184,GO:1901185,GO:1901564,GO:1901698,GO:1901700,GO:1901861,GO:1901863,GO:1902531,GO:1902533,GO:1903429,GO:1903430,GO:1903530,GO:1904396,GO:1904799,GO:1904800,GO:2000026,GO:2001260 - 0.0001106 55.0
WLSH3_k127_5469709_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000007138 237.0
WLSH3_k127_5469709_4 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000001252 221.0
WLSH3_k127_5469709_5 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000007246 220.0
WLSH3_k127_5469709_6 PFAM ABC-type thiamin-related transport system, permease component 1 K16925 - - 0.0000000000000000000000000000000000000000000000000000327 203.0
WLSH3_k127_5469709_7 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000001157 195.0
WLSH3_k127_5469709_9 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000004626 144.0
WLSH3_k127_5515163_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006661 296.0
WLSH3_k127_5515163_1 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002035 262.0
WLSH3_k127_5515163_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000007288 246.0
WLSH3_k127_5515163_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000207 207.0
WLSH3_k127_5515163_4 transcription regulator activity - - - 0.00000000000000000000000000000000000000002476 156.0
WLSH3_k127_5563492_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 486.0
WLSH3_k127_5563492_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 411.0
WLSH3_k127_5563492_2 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 342.0
WLSH3_k127_5563492_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000001223 238.0
WLSH3_k127_5563492_4 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
WLSH3_k127_5563492_5 - - - - 0.0000000000001769 77.0
WLSH3_k127_5563492_6 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000001946 61.0
WLSH3_k127_5580822_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1405.0
WLSH3_k127_5580822_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.438e-225 723.0
WLSH3_k127_5580822_10 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 314.0
WLSH3_k127_5580822_11 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 317.0
WLSH3_k127_5580822_12 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 290.0
WLSH3_k127_5580822_13 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000107 255.0
WLSH3_k127_5580822_14 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
WLSH3_k127_5580822_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000006982 218.0
WLSH3_k127_5580822_16 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000003971 224.0
WLSH3_k127_5580822_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000001878 178.0
WLSH3_k127_5580822_18 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000000000000002747 171.0
WLSH3_k127_5580822_19 - - - - 0.00000000000000000000000000000000000000001916 163.0
WLSH3_k127_5580822_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 595.0
WLSH3_k127_5580822_20 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000002137 152.0
WLSH3_k127_5580822_21 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000004346 143.0
WLSH3_k127_5580822_22 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000003467 78.0
WLSH3_k127_5580822_23 pfam yhs - - - 0.0000000000000003489 82.0
WLSH3_k127_5580822_24 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000001222 79.0
WLSH3_k127_5580822_25 COG1522 Transcriptional regulators - - - 0.000000000004719 77.0
WLSH3_k127_5580822_26 - - - - 0.000000009236 65.0
WLSH3_k127_5580822_27 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000006516 51.0
WLSH3_k127_5580822_28 Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase chloroplastic K13832 - 1.1.1.25,4.2.1.10 0.000004605 59.0
WLSH3_k127_5580822_3 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 503.0
WLSH3_k127_5580822_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 468.0
WLSH3_k127_5580822_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 404.0
WLSH3_k127_5580822_6 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 388.0
WLSH3_k127_5580822_7 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 388.0
WLSH3_k127_5580822_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 410.0
WLSH3_k127_5580822_9 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
WLSH3_k127_5583856_0 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 598.0
WLSH3_k127_5583856_1 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 412.0
WLSH3_k127_5583856_10 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000005064 118.0
WLSH3_k127_5583856_11 - - - - 0.000000000000000000000004865 108.0
WLSH3_k127_5583856_12 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000982 104.0
WLSH3_k127_5583856_13 PFAM glutaredoxin - - - 0.0000000000000000001405 91.0
WLSH3_k127_5583856_14 SpoVT / AbrB like domain - - - 0.00000000001037 68.0
WLSH3_k127_5583856_15 Tetratricopeptide TPR_2 repeat protein - - - 0.00004045 52.0
WLSH3_k127_5583856_2 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 378.0
WLSH3_k127_5583856_3 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 333.0
WLSH3_k127_5583856_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 328.0
WLSH3_k127_5583856_5 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 322.0
WLSH3_k127_5583856_6 PIN domain - - - 0.000000000000000000000000000000000000000000000003494 190.0
WLSH3_k127_5583856_7 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000001076 186.0
WLSH3_k127_5583856_8 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000000001798 164.0
WLSH3_k127_5634705_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 346.0
WLSH3_k127_5634705_1 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 334.0
WLSH3_k127_5634705_10 arginine catabolic process K02626 - 4.1.1.19 0.0000000000001284 74.0
WLSH3_k127_5634705_11 Acetyltransferase (GNAT) domain - - - 0.00000000204 69.0
WLSH3_k127_5634705_12 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.00000001015 64.0
WLSH3_k127_5634705_2 COG COG0714 MoxR-like ATPases General function prediction only - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001528 274.0
WLSH3_k127_5634705_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000006671 247.0
WLSH3_k127_5634705_4 Enoyl-(Acyl carrier protein) reductase K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000194 236.0
WLSH3_k127_5634705_5 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000002697 153.0
WLSH3_k127_5634705_6 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000003804 129.0
WLSH3_k127_5634705_7 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000007156 109.0
WLSH3_k127_5634705_8 COG0521 Molybdopterin biosynthesis enzymes K03638 - 2.7.7.75 0.000000000000000000001594 101.0
WLSH3_k127_5634705_9 Acetyltransferase (GNAT) domain - - - 0.000000000000006002 81.0
WLSH3_k127_5639724_0 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000005562 270.0
WLSH3_k127_5639724_1 - - - - 0.00001106 55.0
WLSH3_k127_5701533_0 GXGXG motif - - - 1.837e-248 786.0
WLSH3_k127_5701533_1 SpoVT / AbrB like domain - - - 0.0009163 43.0
WLSH3_k127_5782080_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 368.0
WLSH3_k127_5782080_1 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 358.0
WLSH3_k127_5782080_2 Uncharacterised ACR, YkgG family COG1556 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 312.0
WLSH3_k127_5782080_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008892 281.0
WLSH3_k127_5782080_4 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000007613 235.0
WLSH3_k127_5782080_5 Membrane - - - 0.0000000000000000000000000000000000000000003554 167.0
WLSH3_k127_5782080_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000002672 147.0
WLSH3_k127_5782080_7 Universal stress protein family - - - 0.000000000000000000000000000000003716 135.0
WLSH3_k127_5782080_8 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000005519 91.0
WLSH3_k127_5782080_9 - - - - 0.00000000000000000007318 94.0
WLSH3_k127_58413_0 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 525.0
WLSH3_k127_58413_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 475.0
WLSH3_k127_58413_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001011 258.0
WLSH3_k127_58413_3 PFAM Peptidase - - - 0.00000000000000000000000000000000000000888 153.0
WLSH3_k127_58413_4 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.00000000000000007213 83.0
WLSH3_k127_5843531_0 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 362.0
WLSH3_k127_5843531_1 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 331.0
WLSH3_k127_5843531_10 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000004695 67.0
WLSH3_k127_5843531_11 Domain of unknown function (DUF749) - - - 0.00000001601 61.0
WLSH3_k127_5843531_12 - - - - 0.000006622 55.0
WLSH3_k127_5843531_13 V4R K07013 - - 0.0003642 52.0
WLSH3_k127_5843531_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001317 286.0
WLSH3_k127_5843531_3 SMART ATPase, AAA type, core K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001885 271.0
WLSH3_k127_5843531_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000001219 197.0
WLSH3_k127_5843531_5 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000000152 133.0
WLSH3_k127_5843531_6 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000001111 125.0
WLSH3_k127_5843531_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000002419 113.0
WLSH3_k127_5843531_8 - - - - 0.000000000000000007876 93.0
WLSH3_k127_5843531_9 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000008499 93.0
WLSH3_k127_5857231_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001777 267.0
WLSH3_k127_5857231_1 ABC-type dipeptide oligopeptide nickel transport system, permease component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006346 258.0
WLSH3_k127_5857231_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000001527 252.0
WLSH3_k127_5857231_3 nitrogen compound transport K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000001987 248.0
WLSH3_k127_5857231_4 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000004231 198.0
WLSH3_k127_5857231_5 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.0000000000000000001373 102.0
WLSH3_k127_5884110_0 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 323.0
WLSH3_k127_5884110_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002057 290.0
WLSH3_k127_5884110_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000003816 207.0
WLSH3_k127_5884110_3 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000004518 197.0
WLSH3_k127_5884110_4 Sodium Bile acid symporter family K03453 - - 0.00000000000000000000000000000000006762 142.0
WLSH3_k127_5921496_0 Proton-conducting membrane transporter K05565,K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 405.0
WLSH3_k127_5921496_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 395.0
WLSH3_k127_5921496_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003295 279.0
WLSH3_k127_5921496_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000006926 228.0
WLSH3_k127_5921496_4 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.00000000000000000000000000000000001135 147.0
WLSH3_k127_5921496_5 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000001687 121.0
WLSH3_k127_5921496_6 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340,K22166 - 1.5.98.3,1.6.5.3 0.000000000000000000000000003207 116.0
WLSH3_k127_5921496_7 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.0000000000000000000000007529 108.0
WLSH3_k127_5921496_8 NADH ubiquinone oxidoreductase subunit 6 (chain J) K00339,K22165 - 1.5.98.3,1.6.5.3 0.000000000005588 72.0
WLSH3_k127_5959296_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 327.0
WLSH3_k127_5959296_1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000001723 228.0
WLSH3_k127_5959296_2 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000000005724 213.0
WLSH3_k127_5959296_3 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000001421 121.0
WLSH3_k127_5959296_4 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000009065 104.0
WLSH3_k127_5959296_5 EamA-like transporter family - - - 0.000000000000000001785 96.0
WLSH3_k127_5959296_6 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000006561 85.0
WLSH3_k127_5959296_7 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000001726 86.0
WLSH3_k127_5959296_8 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000002001 85.0
WLSH3_k127_5959296_9 Protein of unknown function (DUF835) - - - 0.00000000000007724 79.0
WLSH3_k127_6026285_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 473.0
WLSH3_k127_6026285_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 415.0
WLSH3_k127_6026285_2 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 341.0
WLSH3_k127_6026285_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000004962 194.0
WLSH3_k127_6026285_4 ACT domain protein - - - 0.0000000000000006848 82.0
WLSH3_k127_6026285_5 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000001071 60.0
WLSH3_k127_6026285_6 - - - - 0.00000004095 58.0
WLSH3_k127_6066038_0 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 415.0
WLSH3_k127_6066038_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 390.0
WLSH3_k127_6066038_10 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000002463 209.0
WLSH3_k127_6066038_11 PFAM glycosyl transferase group 1 K13677 - 2.4.1.208 0.0000000000000000000000000000000000000000000000544 183.0
WLSH3_k127_6066038_12 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000002514 170.0
WLSH3_k127_6066038_13 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000003268 169.0
WLSH3_k127_6066038_15 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000001528 132.0
WLSH3_k127_6066038_16 - - - - 0.0000000000000000000000001249 120.0
WLSH3_k127_6066038_17 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000001937 109.0
WLSH3_k127_6066038_18 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000000004668 96.0
WLSH3_k127_6066038_19 - - - - 0.000000000000000002329 89.0
WLSH3_k127_6066038_2 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 397.0
WLSH3_k127_6066038_20 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.000000000000000002877 88.0
WLSH3_k127_6066038_21 YjbR - - - 0.0000000000000007696 82.0
WLSH3_k127_6066038_22 - - - - 0.000000002929 60.0
WLSH3_k127_6066038_23 - - - - 0.0000004286 57.0
WLSH3_k127_6066038_24 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00006191 55.0
WLSH3_k127_6066038_25 Acetyltransferase (GNAT) domain - - - 0.0004263 51.0
WLSH3_k127_6066038_26 EamA-like transporter family - - - 0.0008695 50.0
WLSH3_k127_6066038_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 376.0
WLSH3_k127_6066038_4 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 339.0
WLSH3_k127_6066038_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 304.0
WLSH3_k127_6066038_6 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 295.0
WLSH3_k127_6066038_7 ATP-grasp in the biosynthetic pathway with Ter operon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 291.0
WLSH3_k127_6066038_8 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002212 280.0
WLSH3_k127_6066038_9 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000009469 235.0
WLSH3_k127_6108017_0 transcription regulator activity - - - 0.00000000000000000000000000000000004223 140.0
WLSH3_k127_6108017_1 Protein of unknown function (DUF835) - - - 0.00002439 57.0
WLSH3_k127_6312421_0 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004488 290.0
WLSH3_k127_6383606_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000000000000003282 138.0
WLSH3_k127_6648533_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 552.0
WLSH3_k127_6648533_1 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 377.0
WLSH3_k127_6648533_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000001804 138.0
WLSH3_k127_6655116_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000007163 231.0
WLSH3_k127_6655116_1 PFAM Mechanosensitive ion channel K16052 - - 0.000000000000000000004857 107.0
WLSH3_k127_6655116_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13889 - - 0.00000000000000002425 98.0
WLSH3_k127_6655116_3 PKD domain containing protein - - - 0.00000000000003085 88.0
WLSH3_k127_6655116_4 ABC-type multidrug transport system, permease component K01992 - - 0.0000000002273 69.0
WLSH3_k127_6666328_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 441.0
WLSH3_k127_6666328_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 334.0
WLSH3_k127_6666328_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 315.0
WLSH3_k127_6666328_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000001832 193.0
WLSH3_k127_6666328_4 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000000000006905 171.0
WLSH3_k127_6666328_5 SCP-2 sterol transfer family - - - 0.000000000001688 79.0
WLSH3_k127_6666328_6 Homodimerisation domain of SGTA K16365 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0007029,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0010033,GO:0010243,GO:0010256,GO:0010498,GO:0010604,GO:0010605,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0019941,GO:0030162,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031330,GO:0031331,GO:0031333,GO:0032268,GO:0032269,GO:0032270,GO:0032434,GO:0032435,GO:0032436,GO:0032459,GO:0032460,GO:0033036,GO:0033365,GO:0033554,GO:0034613,GO:0034976,GO:0036503,GO:0042176,GO:0042177,GO:0042221,GO:0042802,GO:0042803,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043621,GO:0043632,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045048,GO:0045184,GO:0045732,GO:0045861,GO:0045862,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051205,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051603,GO:0051641,GO:0051716,GO:0060255,GO:0061024,GO:0061136,GO:0065007,GO:0070727,GO:0071704,GO:0071816,GO:0071840,GO:0072657,GO:0080090,GO:0080134,GO:0080135,GO:0090150,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901799,GO:1901800,GO:1903050,GO:1903051,GO:1903052,GO:1903069,GO:1903070,GO:1903071,GO:1903332,GO:1903334,GO:1903362,GO:1903363,GO:1903364,GO:1903573,GO:1903644,GO:1903646,GO:1904288,GO:1904292,GO:1904293,GO:1904294,GO:1905897,GO:1905898,GO:2000058,GO:2000059,GO:2000060 - 0.000001929 56.0
WLSH3_k127_6666328_7 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00001771 48.0
WLSH3_k127_6666328_8 PRC-barrel domain protein - - - 0.0009656 49.0
WLSH3_k127_6674172_0 DNA polymerase type-B family K02319 - 2.7.7.7 1.265e-260 835.0
WLSH3_k127_6674172_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 460.0
WLSH3_k127_6674172_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000126 179.0
WLSH3_k127_6674172_3 Homeodomain-like domain K06933 - - 0.00000000000000000000000006946 110.0
WLSH3_k127_6674172_4 Family of unknown function (DUF5320) - - - 0.000000000000000000797 90.0
WLSH3_k127_6724323_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.252e-253 793.0
WLSH3_k127_6724323_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.966e-243 757.0
WLSH3_k127_6724323_10 CAAX protease self-immunity - - - 0.00000000000000000000000000000005879 141.0
WLSH3_k127_6724323_11 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000002426 130.0
WLSH3_k127_6724323_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000007696 106.0
WLSH3_k127_6724323_13 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000004776 100.0
WLSH3_k127_6724323_14 cheY-homologous receiver domain - - - 0.0000000000000000005785 95.0
WLSH3_k127_6724323_15 RNA binding K09736 - - 0.00000000000000001013 87.0
WLSH3_k127_6724323_16 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000001347 72.0
WLSH3_k127_6724323_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 446.0
WLSH3_k127_6724323_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 371.0
WLSH3_k127_6724323_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008832 275.0
WLSH3_k127_6724323_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002934 255.0
WLSH3_k127_6724323_6 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000001764 162.0
WLSH3_k127_6724323_7 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000000003096 157.0
WLSH3_k127_6724323_8 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000000000000000000000000000000000005593 164.0
WLSH3_k127_6724323_9 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000002978 153.0
WLSH3_k127_6727921_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 5.332e-249 786.0
WLSH3_k127_6727921_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 4.083e-217 706.0
WLSH3_k127_6727921_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000006059 250.0
WLSH3_k127_6727921_11 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000001072 229.0
WLSH3_k127_6727921_12 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000008483 193.0
WLSH3_k127_6727921_13 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000002859 161.0
WLSH3_k127_6727921_14 lactate oxidation K16950 - - 0.0000000000000000000000000000000000000004098 160.0
WLSH3_k127_6727921_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000002309 122.0
WLSH3_k127_6727921_16 Protein of unknown function (DUF2797) - - - 0.00000000000002018 83.0
WLSH3_k127_6727921_17 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000003541 76.0
WLSH3_k127_6727921_2 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 1.314e-212 675.0
WLSH3_k127_6727921_3 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 495.0
WLSH3_k127_6727921_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 439.0
WLSH3_k127_6727921_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 377.0
WLSH3_k127_6727921_6 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 348.0
WLSH3_k127_6727921_7 methanogenesis marker protein 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 344.0
WLSH3_k127_6727921_8 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 307.0
WLSH3_k127_6727921_9 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001 248.0
WLSH3_k127_6744380_0 Type II/IV secretion system protein K07332 - - 3.616e-222 702.0
WLSH3_k127_6744380_1 Type II secretion system K07333 - - 0.00000000000000009318 83.0
WLSH3_k127_6744380_2 Double zinc ribbon - - - 0.0000127 51.0
WLSH3_k127_6749510_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 432.0
WLSH3_k127_6749510_1 Isocitrate isopropylmalate dehydrogenase K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 293.0
WLSH3_k127_6749510_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000004812 259.0
WLSH3_k127_6749510_3 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000003108 190.0
WLSH3_k127_6749510_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000001345 195.0
WLSH3_k127_6749510_5 PFAM CBS domain - - - 0.0000002157 54.0
WLSH3_k127_6750422_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.983e-197 629.0
WLSH3_k127_6750422_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 417.0
WLSH3_k127_6750422_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000242 262.0
WLSH3_k127_6750422_11 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000046 222.0
WLSH3_k127_6750422_12 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000003988 213.0
WLSH3_k127_6750422_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000002856 194.0
WLSH3_k127_6750422_14 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.00000000000000000000000000000000000000000000000003926 190.0
WLSH3_k127_6750422_15 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000001285 197.0
WLSH3_k127_6750422_16 Phenazine biosynthesis protein phzf family - - - 0.0000000000000000000000000000000000000000000005801 178.0
WLSH3_k127_6750422_17 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000003159 173.0
WLSH3_k127_6750422_18 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000004431 147.0
WLSH3_k127_6750422_19 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000000000000000000000001476 134.0
WLSH3_k127_6750422_2 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 408.0
WLSH3_k127_6750422_20 Uncharacterized ArCR, COG1888 K09732 - - 0.0000000000000000000000000004604 115.0
WLSH3_k127_6750422_21 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000001223 132.0
WLSH3_k127_6750422_22 binds to the 23S rRNA K02921 - - 0.00000000000000033 82.0
WLSH3_k127_6750422_23 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000002485 71.0
WLSH3_k127_6750422_24 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.000000000005709 66.0
WLSH3_k127_6750422_25 Bacterial regulatory protein, Fis family K02584 - - 0.000007191 60.0
WLSH3_k127_6750422_26 Transcription factor Pcc1 K09741 - - 0.00001345 52.0
WLSH3_k127_6750422_27 diguanylate cyclase - - - 0.00001642 59.0
WLSH3_k127_6750422_28 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0001622 48.0
WLSH3_k127_6750422_29 exodeoxyribonuclease I activity - - - 0.000316 52.0
WLSH3_k127_6750422_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 398.0
WLSH3_k127_6750422_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 392.0
WLSH3_k127_6750422_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 328.0
WLSH3_k127_6750422_6 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 328.0
WLSH3_k127_6750422_7 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 304.0
WLSH3_k127_6750422_8 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 299.0
WLSH3_k127_6750422_9 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 301.0
WLSH3_k127_6824589_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007856 266.0
WLSH3_k127_6824589_1 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
WLSH3_k127_6824589_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008743,GO:0009066,GO:0009987,GO:0016043,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.1.1.103 0.0000000000001451 72.0
WLSH3_k127_6824589_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.0001416 53.0
WLSH3_k127_6825268_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 3.03e-302 949.0
WLSH3_k127_6825268_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 309.0
WLSH3_k127_6897444_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 303.0
WLSH3_k127_6897444_1 PFAM amidinotransferase K01478,K01482 - 3.5.3.18,3.5.3.6 0.0000000000000000000000000000000000000000000000002459 185.0
WLSH3_k127_6897444_2 Major Facilitator Superfamily - - - 0.0000000000000000000000002958 120.0
WLSH3_k127_6897444_3 PFAM Forkhead-associated protein - - - 0.0000000000000000000000003657 119.0
WLSH3_k127_7056957_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 554.0
WLSH3_k127_7056957_1 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 380.0
WLSH3_k127_7056957_10 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000004419 219.0
WLSH3_k127_7056957_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000245 194.0
WLSH3_k127_7056957_12 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000258 138.0
WLSH3_k127_7056957_13 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000042 135.0
WLSH3_k127_7056957_14 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000004435 125.0
WLSH3_k127_7056957_15 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000001329 117.0
WLSH3_k127_7056957_16 - - - - 0.0000000000000000183 94.0
WLSH3_k127_7056957_17 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000003197 92.0
WLSH3_k127_7056957_18 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001181 85.0
WLSH3_k127_7056957_19 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000002033 72.0
WLSH3_k127_7056957_2 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005586 382.0
WLSH3_k127_7056957_20 - - - - 0.0000000007928 71.0
WLSH3_k127_7056957_21 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000004704 52.0
WLSH3_k127_7056957_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 324.0
WLSH3_k127_7056957_4 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 294.0
WLSH3_k127_7056957_5 translation initiation factor 2 subunit alpha K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 290.0
WLSH3_k127_7056957_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000189 272.0
WLSH3_k127_7056957_7 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000002095 236.0
WLSH3_k127_7056957_8 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001507 224.0
WLSH3_k127_7056957_9 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000001626 222.0
WLSH3_k127_7095879_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000003338 230.0
WLSH3_k127_7095879_1 domain protein K14194 - - 0.0003578 52.0
WLSH3_k127_7146393_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 483.0
WLSH3_k127_7146393_1 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 364.0
WLSH3_k127_7146393_10 Efflux ABC transporter, permease protein K02004 - - 0.000000000000000000000000000000004 149.0
WLSH3_k127_7146393_11 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000001373 149.0
WLSH3_k127_7146393_12 - - - - 0.0000000000000000000009246 105.0
WLSH3_k127_7146393_13 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000014 93.0
WLSH3_k127_7146393_14 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00004603 55.0
WLSH3_k127_7146393_2 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 357.0
WLSH3_k127_7146393_3 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
WLSH3_k127_7146393_4 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 312.0
WLSH3_k127_7146393_5 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000208 263.0
WLSH3_k127_7146393_6 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000009745 246.0
WLSH3_k127_7146393_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
WLSH3_k127_7146393_8 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000004575 222.0
WLSH3_k127_7146393_9 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000007129 181.0
WLSH3_k127_7457274_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 415.0
WLSH3_k127_7457274_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003053 283.0
WLSH3_k127_7457274_10 MoaE protein K21142 - 2.8.1.12 0.00000000000000001251 85.0
WLSH3_k127_7457274_11 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000002594 82.0
WLSH3_k127_7457274_12 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000002433 77.0
WLSH3_k127_7457274_2 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000000000000000000000000003078 251.0
WLSH3_k127_7457274_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000004801 215.0
WLSH3_k127_7457274_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001765 168.0
WLSH3_k127_7457274_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000004432 177.0
WLSH3_k127_7457274_6 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000000963 128.0
WLSH3_k127_7457274_7 Pfam:DUF552 K09152 - - 0.00000000000000000000000000004946 120.0
WLSH3_k127_7457274_8 Response regulator receiver domain - - - 0.000000000000000000000000003764 115.0
WLSH3_k127_7457274_9 DNA-binding transcription factor activity K18297 - - 0.0000000000000000000001949 107.0
WLSH3_k127_7471323_0 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 373.0
WLSH3_k127_7471323_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000001292 170.0
WLSH3_k127_7471323_2 - - - - 0.00000001266 61.0
WLSH3_k127_7486840_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 548.0
WLSH3_k127_7486840_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 479.0
WLSH3_k127_7486840_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 422.0
WLSH3_k127_7486840_3 dyslexia-associated protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0031410,GO:0031982,GO:0043226,GO:0043227,GO:0043229,GO:0044424,GO:0044444,GO:0044464,GO:0097708 - 0.000000144 64.0
WLSH3_k127_7486840_4 Dinitrogenase iron-molybdenum cofactor - - - 0.00005527 51.0
WLSH3_k127_7538274_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 308.0
WLSH3_k127_7538274_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002667 287.0
WLSH3_k127_7538274_3 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.0008753 49.0
WLSH3_k127_7593703_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004584 270.0
WLSH3_k127_7593703_1 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 259.0
WLSH3_k127_7593703_2 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000000005824 106.0
WLSH3_k127_7593703_3 Clostripain family - - - 0.00005419 51.0
WLSH3_k127_7635622_0 COG0531 Amino acid transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 411.0
WLSH3_k127_7635622_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 315.0
WLSH3_k127_7635622_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001143 261.0
WLSH3_k127_7635622_3 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000299 142.0
WLSH3_k127_7635622_4 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000003011 127.0
WLSH3_k127_7635622_5 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000005115 123.0
WLSH3_k127_7635622_6 Peptidase S8 K08651 - 3.4.21.66 0.00000000000000000000000149 122.0
WLSH3_k127_7635622_7 OmpA family - - - 0.000000000001324 83.0
WLSH3_k127_7726713_0 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 395.0
WLSH3_k127_7726713_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 382.0
WLSH3_k127_7726713_3 Fibronectin type III domain - - - 0.000000000001014 80.0
WLSH3_k127_7895862_0 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 387.0
WLSH3_k127_7895862_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 374.0
WLSH3_k127_7895862_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000001617 70.0
WLSH3_k127_7898325_0 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000001433 195.0
WLSH3_k127_7936022_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 1.65e-288 932.0
WLSH3_k127_7936022_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.955e-269 854.0
WLSH3_k127_7936022_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.773e-263 828.0
WLSH3_k127_7936022_3 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 490.0
WLSH3_k127_7936022_4 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000004009 228.0
WLSH3_k127_7936022_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000001409 213.0
WLSH3_k127_7936022_6 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000006233 185.0
WLSH3_k127_7936022_7 DnaB-like helicase C terminal domain - - - 0.0000000000000000000007757 108.0
WLSH3_k127_7936022_8 Double zinc ribbon - - - 0.00001104 58.0
WLSH3_k127_7955525_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 519.0
WLSH3_k127_7955525_1 - - - - 0.000000000000000000000001148 108.0
WLSH3_k127_8026980_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 417.0
WLSH3_k127_8026980_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 388.0
WLSH3_k127_8026980_10 - - - - 0.00003284 48.0
WLSH3_k127_8026980_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
WLSH3_k127_8026980_3 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004821 280.0
WLSH3_k127_8026980_4 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 263.0
WLSH3_k127_8026980_5 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001402 240.0
WLSH3_k127_8026980_6 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000000095 123.0
WLSH3_k127_8026980_7 lipase activity K01083,K11018,K12686,K15349,K21831 GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 3.1.3.8 0.00000000000000000000003652 115.0
WLSH3_k127_8026980_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000009482 102.0
WLSH3_k127_8026980_9 - - - - 0.0000000004084 66.0
WLSH3_k127_8307965_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 338.0
WLSH3_k127_8307965_1 SIS domain K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000001527 183.0
WLSH3_k127_8307965_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000714 175.0
WLSH3_k127_8307965_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000002396 149.0
WLSH3_k127_8307965_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000007847 133.0
WLSH3_k127_8307965_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000008492 100.0
WLSH3_k127_830813_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
WLSH3_k127_830813_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K08323 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000109 252.0
WLSH3_k127_830813_2 Uridine phosphorylase - - - 0.0000000000000000000000000000000000009993 149.0
WLSH3_k127_830813_3 archaeal coiled-coil protein - - - 0.00000000000000000000000000000002103 137.0
WLSH3_k127_830813_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000006216 145.0
WLSH3_k127_830813_5 Tetratricopeptide repeat - - - 0.00000000000000007012 95.0
WLSH3_k127_830813_6 Protein of unknown function DUF89 K09116 - - 0.0000000006455 60.0
WLSH3_k127_830813_7 helix_turn_helix ASNC type K03718 - - 0.00004848 55.0
WLSH3_k127_831843_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.00000000000003519 74.0
WLSH3_k127_831843_1 serine threonine protein kinase - - - 0.00006142 47.0
WLSH3_k127_8329595_0 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001094 286.0
WLSH3_k127_8329595_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000007251 234.0
WLSH3_k127_8329595_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000009519 213.0
WLSH3_k127_8329595_3 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000001234 73.0
WLSH3_k127_8337737_0 Helix-turn-helix domain - - - 0.0000000000002041 78.0
WLSH3_k127_8337737_1 Lrp/AsnC ligand binding domain - - - 0.0001765 46.0
WLSH3_k127_834776_0 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 306.0
WLSH3_k127_834776_1 Fe-S cluster domain protein K03753 - - 0.0000000000000001583 86.0
WLSH3_k127_8426437_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 474.0
WLSH3_k127_8426437_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 385.0
WLSH3_k127_8426437_2 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000548 152.0
WLSH3_k127_8497187_0 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 316.0
WLSH3_k127_8497187_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000006085 225.0
WLSH3_k127_8497187_2 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000005301 211.0
WLSH3_k127_8543235_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 464.0
WLSH3_k127_8543235_1 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 461.0
WLSH3_k127_8543235_10 ribosomal small subunit binding - - - 0.000000002686 68.0
WLSH3_k127_8543235_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 452.0
WLSH3_k127_8543235_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 411.0
WLSH3_k127_8543235_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 353.0
WLSH3_k127_8543235_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 305.0
WLSH3_k127_8543235_6 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000004953 263.0
WLSH3_k127_8543235_7 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000002864 181.0
WLSH3_k127_8543235_8 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.0000000000000000000000000000000000000000000004938 179.0
WLSH3_k127_8543235_9 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000002138 115.0
WLSH3_k127_8782214_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 551.0
WLSH3_k127_8782214_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000000000000002755 204.0
WLSH3_k127_8782214_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000005496 175.0
WLSH3_k127_8782214_3 - - - - 0.00000000000000000000009266 110.0
WLSH3_k127_8782214_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone - - - 0.000000000009935 73.0
WLSH3_k127_8782214_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000001839 71.0
WLSH3_k127_885917_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000001301 207.0
WLSH3_k127_885917_1 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000008371 170.0
WLSH3_k127_885917_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000001655 136.0
WLSH3_k127_885917_3 Methyltransferase domain - - - 0.00000000000000000000000002697 119.0
WLSH3_k127_885917_4 EamA-like transporter family - - - 0.0000007089 60.0
WLSH3_k127_8887491_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1746.0
WLSH3_k127_8887491_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1297.0
WLSH3_k127_8887491_10 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 288.0
WLSH3_k127_8887491_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
WLSH3_k127_8887491_12 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000002433 247.0
WLSH3_k127_8887491_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000007208 235.0
WLSH3_k127_8887491_14 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000000000000000000000000011 203.0
WLSH3_k127_8887491_15 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000000003938 177.0
WLSH3_k127_8887491_16 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000000006191 161.0
WLSH3_k127_8887491_17 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.000000000000000000000000000000000000000188 156.0
WLSH3_k127_8887491_18 COG5598 Trimethylamine corrinoid methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000002071 164.0
WLSH3_k127_8887491_19 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000001552 155.0
WLSH3_k127_8887491_2 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 4.974e-257 869.0
WLSH3_k127_8887491_20 homolog of PrgY (pheromone shutdown protein) - - - 0.000000000000000000000000000000000139 142.0
WLSH3_k127_8887491_21 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000001722 123.0
WLSH3_k127_8887491_22 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000001263 126.0
WLSH3_k127_8887491_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000006356 100.0
WLSH3_k127_8887491_24 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000172 94.0
WLSH3_k127_8887491_25 PFAM Rhomboid family protein K07059 - - 0.00000000000000000004704 102.0
WLSH3_k127_8887491_26 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.00000000000000001959 94.0
WLSH3_k127_8887491_27 Belongs to the eIF-2B alpha beta delta subunits family - - - 0.000000004858 67.0
WLSH3_k127_8887491_28 - - - - 0.0000001907 63.0
WLSH3_k127_8887491_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 604.0
WLSH3_k127_8887491_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 479.0
WLSH3_k127_8887491_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 434.0
WLSH3_k127_8887491_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 418.0
WLSH3_k127_8887491_7 4Fe-4S single cluster domain K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 374.0
WLSH3_k127_8887491_8 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 353.0
WLSH3_k127_8887491_9 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 314.0
WLSH3_k127_8924530_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 610.0
WLSH3_k127_8924530_1 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000004018 143.0
WLSH3_k127_8924530_2 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000002714 144.0
WLSH3_k127_8924530_3 Calcineurin-like phosphoesterase - - - 0.000000000000005108 79.0
WLSH3_k127_8958969_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 263.0
WLSH3_k127_8958969_1 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001281 243.0
WLSH3_k127_8958969_2 - - - - 0.000005306 55.0
WLSH3_k127_9145389_0 leucyl-tRNA aminoacylation K01869 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000258 285.0
WLSH3_k127_9145389_1 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000006128 217.0
WLSH3_k127_9145389_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000000001374 206.0
WLSH3_k127_9145389_3 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.00000000000000000000000000000000000000000000000000004225 194.0
WLSH3_k127_9145389_4 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000004066 162.0
WLSH3_k127_9145389_5 Belongs to the PDCD5 family K06875 - - 0.000000000000000000001061 98.0
WLSH3_k127_9145389_6 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000004171 93.0
WLSH3_k127_9145389_7 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002129 70.0
WLSH3_k127_9210088_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 509.0
WLSH3_k127_9210088_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 324.0
WLSH3_k127_9210088_10 - - - - 0.000000000000000000000000000000006487 140.0
WLSH3_k127_9210088_11 - - - - 0.00000000000000000001554 95.0
WLSH3_k127_9210088_12 - - - - 0.0000007441 61.0
WLSH3_k127_9210088_13 Acetyltransferase (GNAT) domain - - - 0.0001343 50.0
WLSH3_k127_9210088_14 transcriptional - - - 0.0003696 50.0
WLSH3_k127_9210088_2 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 326.0
WLSH3_k127_9210088_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 289.0
WLSH3_k127_9210088_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001548 286.0
WLSH3_k127_9210088_5 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002023 272.0
WLSH3_k127_9210088_6 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006561 284.0
WLSH3_k127_9210088_7 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000003968 242.0
WLSH3_k127_9210088_8 - - - - 0.000000000000000000000000000000000000000005877 168.0
WLSH3_k127_9210088_9 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000001047 167.0
WLSH3_k127_9302164_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.1e-234 755.0
WLSH3_k127_9356478_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008235 261.0
WLSH3_k127_9356478_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000002235 241.0
WLSH3_k127_9356478_2 structural constituent of ribosome K02984 - - 0.000000000000000000000000000000000000000000000000000000000000002948 227.0
WLSH3_k127_9356478_3 PKD domain - - - 0.000000001454 72.0
WLSH3_k127_9356478_4 peptidase M36 K01417 - - 0.00001323 59.0
WLSH3_k127_9357188_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 6.638e-234 745.0
WLSH3_k127_9357188_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 538.0
WLSH3_k127_9357188_2 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 452.0
WLSH3_k127_9357188_3 TIGRFAM Small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006113 417.0
WLSH3_k127_9357188_4 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 307.0
WLSH3_k127_9357188_5 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005149 283.0
WLSH3_k127_9357188_6 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001125 273.0
WLSH3_k127_9357188_7 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000004633 105.0
WLSH3_k127_9357188_8 - - - - 0.000000000000004677 78.0
WLSH3_k127_9373687_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 5.259e-218 702.0
WLSH3_k127_9373687_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.057e-207 666.0
WLSH3_k127_9373687_10 Glycosyl transferase family 2 - - - 0.000000000000002392 85.0
WLSH3_k127_9373687_11 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.00000003539 65.0
WLSH3_k127_9373687_12 Rubrerythrin - - - 0.000009837 56.0
WLSH3_k127_9373687_13 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00004243 57.0
WLSH3_k127_9373687_14 DNA polymerase beta domain-containing protein region - - - 0.00005027 53.0
WLSH3_k127_9373687_15 Phosphomethylpyrimidine kinase type-1 K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00005127 46.0
WLSH3_k127_9373687_2 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 571.0
WLSH3_k127_9373687_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000001429 239.0
WLSH3_k127_9373687_4 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000008784 213.0
WLSH3_k127_9373687_5 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000002202 171.0
WLSH3_k127_9373687_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.000000000000000000009441 101.0
WLSH3_k127_9373687_7 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000051 96.0
WLSH3_k127_9373687_8 PAP2 superfamily - - - 0.000000000000000008072 94.0
WLSH3_k127_9373687_9 Molybdopterin converting factor, small subunit K03636,K21029 - 2.7.7.80 0.0000000000000004051 81.0
WLSH3_k127_9400347_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.146e-201 643.0
WLSH3_k127_9400347_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 442.0
WLSH3_k127_9400347_2 Iron-sulphur cluster biosynthesis K15724 - - 0.00000000000000001388 87.0
WLSH3_k127_959074_0 Nickel-dependent hydrogenase K17993 - 1.12.1.3,1.12.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 340.0
WLSH3_k127_959074_1 Oxidoreductase NAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009669 288.0
WLSH3_k127_959074_2 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001439 282.0
WLSH3_k127_959074_3 hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000008832 201.0
WLSH3_k127_959074_4 PFAM Kelch motif - - - 0.00000000000000000000007972 113.0
WLSH3_k127_959074_6 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.000000004819 68.0
WLSH3_k127_959074_9 - - - - 0.0001668 44.0
WLSH3_k127_9650056_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 327.0
WLSH3_k127_9650056_1 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000006707 228.0
WLSH3_k127_9650056_2 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000002025 163.0
WLSH3_k127_9650056_3 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000000000001962 147.0
WLSH3_k127_9650056_4 histone ubiquitination K10573 GO:0000151,GO:0000209,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006325,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016567,GO:0016569,GO:0016570,GO:0016574,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0031371,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0032991,GO:0033503,GO:0033554,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051603,GO:0051716,GO:0061630,GO:0061659,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 2.3.2.23 0.000000000005979 73.0
WLSH3_k127_9650056_5 to Saccharomyces cerevisiae RPN11 (YFR004W) K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.00000000003558 72.0
WLSH3_k127_9682173_0 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 333.0
WLSH3_k127_9682173_1 Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta K08718,K13756 GO:0001654,GO:0001750,GO:0003008,GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0005575,GO:0005623,GO:0005886,GO:0005929,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0007154,GO:0007165,GO:0007186,GO:0007275,GO:0007423,GO:0007600,GO:0007601,GO:0007602,GO:0007603,GO:0008081,GO:0008150,GO:0008152,GO:0008277,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009150,GO:0009161,GO:0009167,GO:0009259,GO:0009314,GO:0009416,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009605,GO:0009628,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016056,GO:0016787,GO:0016788,GO:0019637,GO:0019693,GO:0019725,GO:0022400,GO:0023051,GO:0023052,GO:0030003,GO:0031090,GO:0031253,GO:0032101,GO:0032501,GO:0032502,GO:0034641,GO:0042278,GO:0042578,GO:0042592,GO:0042622,GO:0042995,GO:0043005,GO:0043010,GO:0043226,GO:0043227,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044425,GO:0044441,GO:0044459,GO:0044463,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0047555,GO:0048513,GO:0048583,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050877,GO:0050896,GO:0050953,GO:0051480,GO:0051606,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060041,GO:0060170,GO:0065007,GO:0065008,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0071944,GO:0072503,GO:0072507,GO:0072521,GO:0097381,GO:0097458,GO:0097730,GO:0097731,GO:0097733,GO:0098588,GO:0098590,GO:0098771,GO:0104004,GO:0120025,GO:0120038,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 3.1.4.35 0.000006652 59.0
WLSH3_k127_974111_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 548.0
WLSH3_k127_974111_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001888 289.0
WLSH3_k127_974111_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007543 278.0
WLSH3_k127_974111_3 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000001742 124.0
WLSH3_k127_9966592_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 436.0
WLSH3_k127_9966592_1 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003997 294.0
WLSH3_k127_9966592_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000104 203.0
WLSH3_k127_9966592_3 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000001106 194.0
WLSH3_k127_9966592_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000001501 192.0
WLSH3_k127_9966592_5 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000002068 143.0
WLSH3_k127_9966592_6 Belongs to the UPF0248 family K09715 - - 0.00000000000000000001014 93.0
WLSH3_k127_9966592_7 Arginase family - - - 0.00000004088 55.0
WLSH3_k127_9992909_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 369.0
WLSH3_k127_9992909_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 362.0
WLSH3_k127_9992909_2 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000005275 237.0
WLSH3_k127_9992909_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.000000000000000000000000000000000000000000000000001275 197.0
WLSH3_k127_9992909_4 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000000000000000000000000000000000000000002375 197.0
WLSH3_k127_9992909_5 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000002614 173.0