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Overview

ID MAG04247
Name WLSH3_bin.27
Sample SMP0111
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurovaceae
Genus BN30871
Species BN30871 sp001493195
Assembly information
Completeness (%) 59.87
Contamination (%) 0.69
GC content (%) 33.0
N50 (bp) 2,547
Genome size (bp) 964,197

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1220

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH3_k127_10018070_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.19e-202 634.0
WLSH3_k127_10018070_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 588.0
WLSH3_k127_10018070_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 481.0
WLSH3_k127_10018070_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008964 230.0
WLSH3_k127_10018070_4 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000004316 121.0
WLSH3_k127_10027652_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 390.0
WLSH3_k127_1009604_0 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 452.0
WLSH3_k127_1009604_1 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000000000000000000000000001922 209.0
WLSH3_k127_1009604_2 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000001161 162.0
WLSH3_k127_1011719_0 hydrolase, TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 394.0
WLSH3_k127_1011719_1 Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 350.0
WLSH3_k127_1011719_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000008209 231.0
WLSH3_k127_1011719_3 Receptor - - - 0.00000000001731 67.0
WLSH3_k127_10159354_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 472.0
WLSH3_k127_10159354_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 456.0
WLSH3_k127_10159354_2 Cytochrome c - - - 0.00000000000000000000000004503 111.0
WLSH3_k127_10169933_0 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000001324 72.0
WLSH3_k127_10169933_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000001324 69.0
WLSH3_k127_10194692_0 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 453.0
WLSH3_k127_10236970_0 2-hydroxyglutaryl-CoA dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 599.0
WLSH3_k127_10236970_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 434.0
WLSH3_k127_10260788_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 355.0
WLSH3_k127_10260788_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 346.0
WLSH3_k127_10299625_0 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 329.0
WLSH3_k127_10299625_1 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
WLSH3_k127_10299625_2 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000001033 74.0
WLSH3_k127_10338189_0 Tryptophan halogenase K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 609.0
WLSH3_k127_10338189_1 von willebrand factor, type A K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004679 485.0
WLSH3_k127_10338189_2 Domain of unknown function (DUF4347) - - - 0.0000000000000002844 92.0
WLSH3_k127_10338189_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K13735 - - 0.0000000000000008808 91.0
WLSH3_k127_10367001_0 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 544.0
WLSH3_k127_10367001_1 - - - - 0.0000000000000000000000000000000000000000000001669 171.0
WLSH3_k127_10367001_2 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000001541 148.0
WLSH3_k127_10424817_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 589.0
WLSH3_k127_10424817_1 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
WLSH3_k127_10424817_2 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009715 264.0
WLSH3_k127_10441255_0 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 347.0
WLSH3_k127_10441255_1 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000002014 130.0
WLSH3_k127_10441255_2 Belongs to the ATPase B chain family K02109 - - 0.0000000000000000008529 92.0
WLSH3_k127_10441255_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000009366 51.0
WLSH3_k127_10495650_0 DNA polymerase K02337 - 2.7.7.7 1.741e-201 632.0
WLSH3_k127_10578514_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 527.0
WLSH3_k127_10578514_1 Transcriptional regulator K03892 - - 0.00000000000000000000000000000000000000000000002174 172.0
WLSH3_k127_10613006_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 3.586e-207 648.0
WLSH3_k127_10613006_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000004085 55.0
WLSH3_k127_1061698_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 323.0
WLSH3_k127_1061698_1 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.00000000000004952 75.0
WLSH3_k127_10638013_0 Oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 430.0
WLSH3_k127_10638013_1 Oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 385.0
WLSH3_k127_10638013_2 oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000006711 232.0
WLSH3_k127_10638013_3 Oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000008876 117.0
WLSH3_k127_10705451_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 297.0
WLSH3_k127_10705451_1 Transcriptional regulator - - - 0.0000000000000000000000000005328 117.0
WLSH3_k127_10705451_2 o-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000004379 87.0
WLSH3_k127_1071237_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 377.0
WLSH3_k127_1071237_1 - - - - 0.00000009445 53.0
WLSH3_k127_1071248_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1159.0
WLSH3_k127_1071248_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 442.0
WLSH3_k127_10736214_0 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005445 248.0
WLSH3_k127_10736214_1 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000001107 182.0
WLSH3_k127_1077947_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.565e-194 612.0
WLSH3_k127_1077947_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000004103 243.0
WLSH3_k127_1077947_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000001455 233.0
WLSH3_k127_1077947_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
WLSH3_k127_10783467_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 574.0
WLSH3_k127_10786146_0 COG0841 Cation multidrug efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 436.0
WLSH3_k127_10786146_1 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000004144 216.0
WLSH3_k127_10797606_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 420.0
WLSH3_k127_10797606_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 340.0
WLSH3_k127_10797606_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007749 246.0
WLSH3_k127_10829282_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 542.0
WLSH3_k127_10829282_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004826 274.0
WLSH3_k127_1087399_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1216.0
WLSH3_k127_1087399_1 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000001752 173.0
WLSH3_k127_1087399_2 integral membrane protein - - - 0.0000000000000000000002097 102.0
WLSH3_k127_10890099_0 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 338.0
WLSH3_k127_10890099_1 Carboxylesterase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 305.0
WLSH3_k127_10890099_2 -acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
WLSH3_k127_10890099_3 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000492 93.0
WLSH3_k127_10903197_0 TaqI-like C-terminal specificity domain - - - 1.455e-247 786.0
WLSH3_k127_10915184_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.5e-323 995.0
WLSH3_k127_10915184_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 301.0
WLSH3_k127_10915184_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005772 265.0
WLSH3_k127_10915184_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000005053 102.0
WLSH3_k127_10917878_0 hmm pf04305 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 362.0
WLSH3_k127_10917878_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 310.0
WLSH3_k127_10917878_2 COGs COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000001544 188.0
WLSH3_k127_10941705_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 466.0
WLSH3_k127_11065247_0 Domain of unknown function DUF87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 575.0
WLSH3_k127_1107224_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002168 276.0
WLSH3_k127_1107224_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000001346 240.0
WLSH3_k127_11083235_0 DEAD DEAH box helicase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 375.0
WLSH3_k127_11083235_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000001104 244.0
WLSH3_k127_1112090_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.276e-222 704.0
WLSH3_k127_1112090_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000001478 64.0
WLSH3_k127_11124825_0 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 286.0
WLSH3_k127_11124825_1 Hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000002358 237.0
WLSH3_k127_11138947_0 4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 390.0
WLSH3_k127_11138947_1 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 383.0
WLSH3_k127_11138947_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
WLSH3_k127_11138947_3 uracil DNA glycosylase K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000004627 210.0
WLSH3_k127_11212512_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1014.0
WLSH3_k127_11212512_1 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000001026 216.0
WLSH3_k127_11290302_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 475.0
WLSH3_k127_11290302_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000006571 157.0
WLSH3_k127_11290302_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000000008638 153.0
WLSH3_k127_11344436_0 Belongs to the AAA ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 466.0
WLSH3_k127_11356377_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 317.0
WLSH3_k127_11356377_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004418 256.0
WLSH3_k127_11356377_2 - K08993 - - 0.000000000000000000000000000000000000000000000000000000004838 203.0
WLSH3_k127_11356377_3 TonB dependent receptor K16092 - - 0.00000000000000000000000000000000000000008388 156.0
WLSH3_k127_1136796_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 496.0
WLSH3_k127_1136796_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000005641 71.0
WLSH3_k127_11380796_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005167 261.0
WLSH3_k127_11380796_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000004874 148.0
WLSH3_k127_11471427_0 ATP-binding protein K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 425.0
WLSH3_k127_11471427_1 ABC transporter permease K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000001517 237.0
WLSH3_k127_11471427_2 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000003897 222.0
WLSH3_k127_11488719_0 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 287.0
WLSH3_k127_11488719_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000002187 165.0
WLSH3_k127_11529958_0 transporter - - - 7.752e-211 664.0
WLSH3_k127_11529958_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000003915 256.0
WLSH3_k127_11529958_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000006671 113.0
WLSH3_k127_11529958_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.0000000000000000000000004479 107.0
WLSH3_k127_11566497_0 Arginosuccinate synthase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 417.0
WLSH3_k127_11566497_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000006685 119.0
WLSH3_k127_1160536_0 RecO N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006566 271.0
WLSH3_k127_1160536_1 transcription regulator containing HTH domain K18831 - - 0.000000000000000000000000000000000000003108 149.0
WLSH3_k127_1160536_2 protein conserved in bacteria K19166 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043487,GO:0043488,GO:0044237,GO:0044238,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1903311,GO:2000112,GO:2000113 - 0.000001696 50.0
WLSH3_k127_1185032_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 305.0
WLSH3_k127_1185032_1 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000002807 234.0
WLSH3_k127_1185032_2 tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000007026 202.0
WLSH3_k127_1193856_0 protein involved in exopolysaccharide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 430.0
WLSH3_k127_1193856_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000004424 123.0
WLSH3_k127_1193856_2 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.000000002177 59.0
WLSH3_k127_1200107_0 Ribonuclease K12573 - - 5.518e-268 839.0
WLSH3_k127_1200107_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 304.0
WLSH3_k127_1200107_2 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000006671 113.0
WLSH3_k127_1206914_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 3.372e-232 736.0
WLSH3_k127_1206914_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 327.0
WLSH3_k127_1206914_2 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000001891 268.0
WLSH3_k127_1206914_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000003186 217.0
WLSH3_k127_1206914_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000003707 100.0
WLSH3_k127_1254001_0 UPF0313 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 391.0
WLSH3_k127_1254001_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000001238 117.0
WLSH3_k127_1295987_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.556e-273 854.0
WLSH3_k127_1295987_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 357.0
WLSH3_k127_1295987_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000008562 90.0
WLSH3_k127_1300282_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 589.0
WLSH3_k127_1300282_1 Peptidase, M16 - - - 0.00000000000000000000000000000007613 128.0
WLSH3_k127_1335748_0 Mg chelatase-related protein K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 596.0
WLSH3_k127_1335748_1 Belongs to the UPF0324 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 464.0
WLSH3_k127_1335748_2 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000001959 221.0
WLSH3_k127_1335748_3 Cytochrome c family protein - - - 0.000000000000000000000000000002564 127.0
WLSH3_k127_1342893_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 2.019e-207 650.0
WLSH3_k127_1342893_1 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 323.0
WLSH3_k127_1342893_2 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004827 252.0
WLSH3_k127_1342893_3 pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000001034 159.0
WLSH3_k127_1342893_4 Hydrolase K01091 - 3.1.3.18 0.000000004797 58.0
WLSH3_k127_1364679_0 homoserine dehydrogenase K00003 - 1.1.1.3 2.703e-195 616.0
WLSH3_k127_1364679_1 Aminotransferase K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006906 340.0
WLSH3_k127_1371156_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1911.0
WLSH3_k127_1371327_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 555.0
WLSH3_k127_1371327_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 0.00000000000000000000000000000000002512 135.0
WLSH3_k127_1384750_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 588.0
WLSH3_k127_1384750_1 Dipeptidase K01270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 420.0
WLSH3_k127_1384750_2 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 355.0
WLSH3_k127_1384750_3 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000113 186.0
WLSH3_k127_1384750_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000005761 162.0
WLSH3_k127_1384750_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000002363 94.0
WLSH3_k127_1395231_0 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 512.0
WLSH3_k127_1395231_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000002912 89.0
WLSH3_k127_1424765_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1864.0
WLSH3_k127_1424765_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.541e-265 823.0
WLSH3_k127_1424765_2 signal transduction sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008956 242.0
WLSH3_k127_1439578_0 COG1459 Type II secretory pathway, component PulF K02455,K02653 - - 0.00000000000000000000000000000000000000000000000001442 184.0
WLSH3_k127_1439578_1 Belongs to the ParB family K03497 - - 0.0000000000000000000000002643 116.0
WLSH3_k127_1439578_2 AAA domain K03496 - - 0.000000000000000000003687 97.0
WLSH3_k127_1500032_0 Hydrogenase, large subunit K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 455.0
WLSH3_k127_1500032_1 Small subunit K05927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 0.0000000000000000000000001296 108.0
WLSH3_k127_1530386_0 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 612.0
WLSH3_k127_1530386_1 PFAM Lytic transglycosylase catalytic K08307 - - 0.0001651 44.0
WLSH3_k127_1598413_0 Putative FMN-binding domain K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003444 243.0
WLSH3_k127_1598413_1 SAM-dependent methyltransferase - - - 0.000000000000000000000000000000000000000002584 163.0
WLSH3_k127_1598413_2 PIN domain - - - 0.0000000000000000000000000000000000000372 146.0
WLSH3_k127_1598413_3 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000007012 113.0
WLSH3_k127_1598413_4 DREV methyltransferase - - - 0.00000000000000000000492 93.0
WLSH3_k127_1655448_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000002464 241.0
WLSH3_k127_1655448_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000003273 215.0
WLSH3_k127_1668627_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 436.0
WLSH3_k127_1668627_1 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000001118 211.0
WLSH3_k127_168365_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 510.0
WLSH3_k127_168365_1 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 376.0
WLSH3_k127_169388_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000843 241.0
WLSH3_k127_169388_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000007509 216.0
WLSH3_k127_169388_2 - - - - 0.000003578 49.0
WLSH3_k127_169388_3 Tetratricopeptide repeat - - - 0.00003895 53.0
WLSH3_k127_1702529_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002117 243.0
WLSH3_k127_1702529_1 Zn-dependent protease with chaperone function K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000004605 236.0
WLSH3_k127_1758821_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 455.0
WLSH3_k127_176832_0 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 381.0
WLSH3_k127_176832_1 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000006091 253.0
WLSH3_k127_176832_3 Ferredoxin K05337 - - 0.00000000000000000000000000000000000000015 151.0
WLSH3_k127_1777322_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 9.368e-227 708.0
WLSH3_k127_1777322_1 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 381.0
WLSH3_k127_1777322_2 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 316.0
WLSH3_k127_1777322_4 Thioredoxin-like - - - 0.0001036 50.0
WLSH3_k127_1782907_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1064.0
WLSH3_k127_1782907_1 ATP-grasp domain - - - 1.064e-205 658.0
WLSH3_k127_1782907_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 425.0
WLSH3_k127_1782907_3 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
WLSH3_k127_1792693_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000006706 191.0
WLSH3_k127_1792693_1 Domain of unknown function (DUF1330) - - - 0.0000000000000000000006194 97.0
WLSH3_k127_1792693_2 Protein of unknown function (DUF3995) - - - 0.000000000002367 70.0
WLSH3_k127_1814249_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.471e-229 715.0
WLSH3_k127_1814249_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 397.0
WLSH3_k127_1814249_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000003966 239.0
WLSH3_k127_1829258_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 309.0
WLSH3_k127_1829258_1 - - - - 0.0000000000000000000000000000000000000000000362 162.0
WLSH3_k127_1851352_0 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000394 205.0
WLSH3_k127_1851352_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000002627 95.0
WLSH3_k127_1869346_0 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001811 241.0
WLSH3_k127_1869346_1 Metal-dependent hydrolase K07043 - - 0.000000000001102 68.0
WLSH3_k127_1884411_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 548.0
WLSH3_k127_1898616_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 535.0
WLSH3_k127_1904975_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.04e-321 990.0
WLSH3_k127_1904975_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 338.0
WLSH3_k127_1904975_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000006221 200.0
WLSH3_k127_1904975_3 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.0000000000000000000000000000000000000000000003812 175.0
WLSH3_k127_1904975_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000008485 104.0
WLSH3_k127_1935295_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K17050 - - 1.134e-293 907.0
WLSH3_k127_1935295_1 4Fe-4S dicluster domain K17051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 409.0
WLSH3_k127_1958826_0 Zeta toxin - - - 0.0000000000000000000000000000000000000000000002872 169.0
WLSH3_k127_1958826_1 PFAM peptidase M48 Ste24p K03799 - - 0.000000000000000000000000000000000768 141.0
WLSH3_k127_2010563_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000005408 235.0
WLSH3_k127_2010563_1 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000003397 229.0
WLSH3_k127_2029718_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1121.0
WLSH3_k127_2038608_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 469.0
WLSH3_k127_2038608_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 - 0.00000000000000000000000000004345 116.0
WLSH3_k127_2081608_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 4.199e-194 610.0
WLSH3_k127_2081608_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 539.0
WLSH3_k127_2081608_2 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 447.0
WLSH3_k127_2081608_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 437.0
WLSH3_k127_2081608_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 394.0
WLSH3_k127_2081608_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000893 250.0
WLSH3_k127_21018_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 2.535e-209 659.0
WLSH3_k127_21018_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000002721 211.0
WLSH3_k127_2103945_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.663e-202 635.0
WLSH3_k127_2103945_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000007272 229.0
WLSH3_k127_2103945_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000844 98.0
WLSH3_k127_2103945_3 - - - - 0.00002197 50.0
WLSH3_k127_2112309_0 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 432.0
WLSH3_k127_2112309_1 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000002535 198.0
WLSH3_k127_2112309_2 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 0.000000000002693 66.0
WLSH3_k127_211406_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 380.0
WLSH3_k127_211406_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007907 265.0
WLSH3_k127_211406_2 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.0000000000000000000000000000000005559 133.0
WLSH3_k127_2116023_0 Protein of unknown function (DUF819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 296.0
WLSH3_k127_2184674_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 5.359e-212 666.0
WLSH3_k127_2184674_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 374.0
WLSH3_k127_2184674_2 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002015 270.0
WLSH3_k127_2184674_3 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000005116 224.0
WLSH3_k127_2184674_4 PFAM S23 ribosomal protein - - - 0.0000000000000000000000000000000000000000006624 159.0
WLSH3_k127_2184691_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 426.0
WLSH3_k127_2184691_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 301.0
WLSH3_k127_2184691_2 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000005052 126.0
WLSH3_k127_2291936_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000004035 133.0
WLSH3_k127_2291936_1 GatB Yqey family protein K09117 - - 0.0000000000000000000000000000003863 124.0
WLSH3_k127_2291936_2 - - - - 0.000000000000000000005188 94.0
WLSH3_k127_2336522_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.569e-209 656.0
WLSH3_k127_2336522_1 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 508.0
WLSH3_k127_2336522_2 DNA replication regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009017 243.0
WLSH3_k127_2336522_3 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000009868 187.0
WLSH3_k127_2336522_4 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000005464 179.0
WLSH3_k127_2359076_0 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 484.0
WLSH3_k127_2359076_1 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine - - - 0.0000000000000000000000000000000000000000000000003366 177.0
WLSH3_k127_2395070_0 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000001212 208.0
WLSH3_k127_2395070_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000004606 188.0
WLSH3_k127_2395070_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000002629 177.0
WLSH3_k127_2395070_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000003156 57.0
WLSH3_k127_240791_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.213e-266 826.0
WLSH3_k127_2425203_0 Terminase RNAseH like domain K06909 - - 0.000000000000000000000000000000000000000172 152.0
WLSH3_k127_243412_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000804 600.0
WLSH3_k127_2446196_0 Belongs to the UbiD family K03182 - 4.1.1.98 6.057e-295 914.0
WLSH3_k127_2446196_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
WLSH3_k127_2467048_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.019e-221 694.0
WLSH3_k127_2467048_1 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000000106 163.0
WLSH3_k127_2467048_2 - - - - 0.000000000000000000001557 94.0
WLSH3_k127_2467048_3 TaqI-like C-terminal specificity domain - - - 0.000000000000000002551 85.0
WLSH3_k127_2467351_0 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 396.0
WLSH3_k127_2467351_1 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.0000000000000000000000000000000000002136 145.0
WLSH3_k127_2467351_2 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000000004782 63.0
WLSH3_k127_2473365_0 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 480.0
WLSH3_k127_2473365_1 molybdopterin converting factor K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000008865 236.0
WLSH3_k127_2473365_2 molybdopterin converting factor K03636 - - 0.0000000000000000000000000005816 114.0
WLSH3_k127_2473365_3 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000007888 96.0
WLSH3_k127_2473365_4 phage repressor - - - 0.00000001203 56.0
WLSH3_k127_2490810_0 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000001765 195.0
WLSH3_k127_2490810_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000008318 126.0
WLSH3_k127_2490810_2 twitching motility protein K02669 - - 0.00000000000000005929 81.0
WLSH3_k127_2490810_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000004629 49.0
WLSH3_k127_2570168_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.104e-250 777.0
WLSH3_k127_2570168_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 289.0
WLSH3_k127_2570168_2 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000003189 127.0
WLSH3_k127_2570168_3 oxidoreductase - - - 0.0000000000006915 71.0
WLSH3_k127_2594644_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 7.209e-234 727.0
WLSH3_k127_2594644_1 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 582.0
WLSH3_k127_2594644_2 membrane-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008209 226.0
WLSH3_k127_2594644_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000001716 192.0
WLSH3_k127_2602737_0 Pilus assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 330.0
WLSH3_k127_2602737_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000003625 54.0
WLSH3_k127_2619819_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 3.76e-211 662.0
WLSH3_k127_2619819_1 DNA polymerase K02337 - 2.7.7.7 0.000000000000000000001093 98.0
WLSH3_k127_2650090_0 phosphohydrolase (DHH superfamily) K07097 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 411.0
WLSH3_k127_2650090_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 297.0
WLSH3_k127_2650090_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000003536 166.0
WLSH3_k127_2705836_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 472.0
WLSH3_k127_2748051_0 receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 426.0
WLSH3_k127_2748051_1 4Fe-4S binding domain - - - 0.00000000003558 72.0
WLSH3_k127_277505_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000003193 135.0
WLSH3_k127_2806725_0 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 349.0
WLSH3_k127_2806725_1 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000006443 167.0
WLSH3_k127_2828748_0 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.666e-196 617.0
WLSH3_k127_2828748_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.00000000000000009143 80.0
WLSH3_k127_2850741_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1439.0
WLSH3_k127_2850741_1 Sodium hydrogen exchanger - - - 0.0000000000000000004558 89.0
WLSH3_k127_2854532_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 394.0
WLSH3_k127_2854532_1 esterase of the alpha beta hydrolase fold K07002 - - 0.00000000000000000000000001936 110.0
WLSH3_k127_2855433_0 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 340.0
WLSH3_k127_2855433_1 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000001292 181.0
WLSH3_k127_2870444_0 Major facilitator superfamily K03762 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 400.0
WLSH3_k127_2870444_1 - - - - 0.0000000000000000000000000001251 117.0
WLSH3_k127_2883856_0 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 394.0
WLSH3_k127_2883856_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000003596 124.0
WLSH3_k127_2883856_2 peptidase U32 family K08303 - - 0.000000000000000000000004578 102.0
WLSH3_k127_2888953_0 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 576.0
WLSH3_k127_2888953_1 hydrogenase expression formation protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 464.0
WLSH3_k127_2888953_2 Hydrogenase K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 391.0
WLSH3_k127_2888953_3 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.000000000000000000000000000000000000000000000000000000001086 210.0
WLSH3_k127_2888953_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000009999 147.0
WLSH3_k127_2888953_5 hydrogenase assembly chaperone HypC K04653 - - 0.000000000000000000000000000002438 122.0
WLSH3_k127_2888953_6 PDGLE domain K02009 - - 0.0000000000000000002532 91.0
WLSH3_k127_2888953_7 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000001752 59.0
WLSH3_k127_2888953_8 transmembrane transporter activity K02007,K02008 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000043 53.0
WLSH3_k127_2901467_0 o-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 499.0
WLSH3_k127_2901467_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003872 251.0
WLSH3_k127_2901467_2 - - - - 0.00000000000000000002477 100.0
WLSH3_k127_2902858_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 443.0
WLSH3_k127_2902858_2 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000002766 100.0
WLSH3_k127_2902858_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000001284 57.0
WLSH3_k127_2915586_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000003187 214.0
WLSH3_k127_2915586_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000001017 194.0
WLSH3_k127_292436_0 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 284.0
WLSH3_k127_292436_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000002127 227.0
WLSH3_k127_2939621_0 Hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 480.0
WLSH3_k127_2939621_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005097 253.0
WLSH3_k127_294747_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 468.0
WLSH3_k127_2950922_0 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000008661 167.0
WLSH3_k127_2950922_1 - - - - 0.00000000000000000000000003149 112.0
WLSH3_k127_2995593_0 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 1.426e-214 674.0
WLSH3_k127_2995593_1 SIR2-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 313.0
WLSH3_k127_2995593_2 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001781 269.0
WLSH3_k127_2995593_3 nitrogen fixation protein FixT K02593 - - 0.00000000000000000000000000000009927 125.0
WLSH3_k127_3031340_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.823e-194 611.0
WLSH3_k127_3031340_1 rod shape-determining protein mreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 433.0
WLSH3_k127_3031340_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 394.0
WLSH3_k127_3031340_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000002017 249.0
WLSH3_k127_3031340_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000004346 71.0
WLSH3_k127_3043079_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 329.0
WLSH3_k127_3043079_1 membrane - - - 0.000000000000000000000000000000000000000000000000002133 186.0
WLSH3_k127_3049591_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 2.332e-194 610.0
WLSH3_k127_3049591_1 - - - - 0.0000000000000000000000000000000000000000000000000000000005907 205.0
WLSH3_k127_3090353_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 424.0
WLSH3_k127_3090353_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000007481 217.0
WLSH3_k127_3130898_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1429.0
WLSH3_k127_3130898_1 COG0732 Restriction endonuclease S subunits K01154 - 3.1.21.3 0.00000000002939 65.0
WLSH3_k127_3147762_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 344.0
WLSH3_k127_3147762_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000004962 248.0
WLSH3_k127_3147762_2 type I restriction-modification system K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000001601 187.0
WLSH3_k127_3147762_3 Resolvase, N terminal domain - - - 0.0007745 42.0
WLSH3_k127_3152565_0 molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 361.0
WLSH3_k127_3152565_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 302.0
WLSH3_k127_3152565_2 Polysulphide reductase NrfD K00185 - - 0.00000000000000000000000000000000000000000000002741 172.0
WLSH3_k127_3207705_0 ABC transporter, ATP-binding protein K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 477.0
WLSH3_k127_3212374_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002721 277.0
WLSH3_k127_3212374_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000163 186.0
WLSH3_k127_3212374_2 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000004191 190.0
WLSH3_k127_3246834_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 589.0
WLSH3_k127_3246834_2 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000001127 185.0
WLSH3_k127_325073_0 Protein of unknown function (DUF808) K09781 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 357.0
WLSH3_k127_325073_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 337.0
WLSH3_k127_325073_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000001993 165.0
WLSH3_k127_325073_3 Sel1 domain protein repeat-containing protein K07126 GO:0002682,GO:0002683,GO:0002694,GO:0002695,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0019862,GO:0019865,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050794,GO:0050865,GO:0050866,GO:0065007,GO:1902563,GO:1902564 - 0.0000000000000000000000000000000000000000006114 164.0
WLSH3_k127_325073_4 - - - - 0.000000000000000001437 89.0
WLSH3_k127_325073_5 - - - - 0.0000000000000009024 81.0
WLSH3_k127_325073_6 CHAD - - - 0.00009044 53.0
WLSH3_k127_3264603_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 565.0
WLSH3_k127_3264603_1 metallophosphoesterase K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 362.0
WLSH3_k127_3264603_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 327.0
WLSH3_k127_3264603_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000005351 121.0
WLSH3_k127_3279532_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.5e-249 775.0
WLSH3_k127_3279532_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 362.0
WLSH3_k127_3279532_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000001146 201.0
WLSH3_k127_3338759_0 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 295.0
WLSH3_k127_3338759_1 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000002707 119.0
WLSH3_k127_3338759_2 Lipopolysaccharide-assembly - - - 0.0001104 48.0
WLSH3_k127_3354478_0 S1 domain K00243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 313.0
WLSH3_k127_3354478_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000003346 217.0
WLSH3_k127_3354478_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000004782 63.0
WLSH3_k127_337319_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 315.0
WLSH3_k127_337319_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000001324 192.0
WLSH3_k127_3452116_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000002114 237.0
WLSH3_k127_3452116_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000005066 188.0
WLSH3_k127_3452116_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000302 167.0
WLSH3_k127_3452116_3 RNA-binding protein - - - 0.00000000000000000000000000000000018 135.0
WLSH3_k127_3452116_4 metal-binding, possibly nucleic acid-binding protein - - - 0.000000000000000000000000000001792 124.0
WLSH3_k127_3452116_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000004755 101.0
WLSH3_k127_3465083_0 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000001646 197.0
WLSH3_k127_3465083_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000007686 155.0
WLSH3_k127_3509790_0 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000001069 237.0
WLSH3_k127_3509790_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000001795 178.0
WLSH3_k127_3509790_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000006668 57.0
WLSH3_k127_3538507_0 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 379.0
WLSH3_k127_3538507_1 Diguanylate cyclase - - - 0.00000000000000000000000000003608 121.0
WLSH3_k127_3538507_2 leucine binding - - - 0.00000217 51.0
WLSH3_k127_356523_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.898e-215 674.0
WLSH3_k127_356523_1 CYTH K01768 - 4.6.1.1 0.00000000009947 63.0
WLSH3_k127_3565894_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
WLSH3_k127_3565894_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000001745 140.0
WLSH3_k127_3565894_2 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000001156 109.0
WLSH3_k127_3598904_0 DEAD DEAH box helicase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 447.0
WLSH3_k127_3616197_0 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000006185 143.0
WLSH3_k127_3616197_1 repeat protein - - - 0.0000000000000000000000000000002867 131.0
WLSH3_k127_3616197_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000172 120.0
WLSH3_k127_362241_0 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005568 297.0
WLSH3_k127_362241_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000002568 130.0
WLSH3_k127_362241_2 - - - - 0.000000000000000000000000002125 115.0
WLSH3_k127_3638386_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 372.0
WLSH3_k127_3638386_1 Belongs to the bacterial histone-like protein family K03530 - - 0.00000001711 55.0
WLSH3_k127_3657214_0 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 305.0
WLSH3_k127_3657214_1 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000000000000000000000000000000000000000000945 192.0
WLSH3_k127_3657214_2 Endonuclease Exonuclease phosphatase - - - 0.0006651 42.0
WLSH3_k127_369541_0 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000005717 188.0
WLSH3_k127_369541_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000003468 141.0
WLSH3_k127_369541_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000001557 60.0
WLSH3_k127_3722018_0 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 292.0
WLSH3_k127_3722018_1 repeat protein - - - 0.000000000000000000000000000000000000000000001533 166.0
WLSH3_k127_3722018_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000003573 98.0
WLSH3_k127_3775625_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1105.0
WLSH3_k127_3775625_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.03e-222 695.0
WLSH3_k127_3775625_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 359.0
WLSH3_k127_3775625_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000007679 223.0
WLSH3_k127_3775625_4 - - - - 0.0000000005691 63.0
WLSH3_k127_3810888_0 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 511.0
WLSH3_k127_3810888_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 501.0
WLSH3_k127_3810888_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000154 258.0
WLSH3_k127_382730_0 peptidase U32 family K08303 - - 4.784e-199 624.0
WLSH3_k127_3835091_0 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 479.0
WLSH3_k127_3835091_1 cytochrome - - - 0.000000000001358 70.0
WLSH3_k127_3842770_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 7.078e-241 755.0
WLSH3_k127_3842770_1 Na H antiporter - - - 0.0000000000000000000000000000000000002425 142.0
WLSH3_k127_3842770_2 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000002803 126.0
WLSH3_k127_3883043_0 ABC transporter, transmembrane region K12541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 578.0
WLSH3_k127_3883043_1 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 524.0
WLSH3_k127_3883043_2 Outer membrane efflux protein K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000002163 250.0
WLSH3_k127_3892373_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 505.0
WLSH3_k127_3892373_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002426 241.0
WLSH3_k127_3905026_0 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 416.0
WLSH3_k127_3905026_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005646 413.0
WLSH3_k127_3905026_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 308.0
WLSH3_k127_3905026_3 PhoU family K02039 - - 0.0000000000000000000000000000000000000001195 158.0
WLSH3_k127_3905026_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000003467 78.0
WLSH3_k127_394109_0 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 297.0
WLSH3_k127_394109_1 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008158 254.0
WLSH3_k127_394109_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000003131 155.0
WLSH3_k127_394109_3 - - - - 0.000000000000000003866 85.0
WLSH3_k127_3941544_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 482.0
WLSH3_k127_3972448_0 Na H antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 490.0
WLSH3_k127_3984798_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 587.0
WLSH3_k127_3990027_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 497.0
WLSH3_k127_3990027_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 386.0
WLSH3_k127_3990027_2 protein conserved in bacteria K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 314.0
WLSH3_k127_3990027_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000005401 205.0
WLSH3_k127_3994168_0 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 9.54e-257 794.0
WLSH3_k127_3994168_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 1.502e-219 686.0
WLSH3_k127_3994168_2 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 589.0
WLSH3_k127_3994168_3 lipopolysaccharide biosynthesis protein K13016 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 549.0
WLSH3_k127_3994168_4 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 338.0
WLSH3_k127_3994168_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
WLSH3_k127_3994168_6 TOBE domain K02019 - - 0.00000000000000000000000000000000000000000000000003598 183.0
WLSH3_k127_4024538_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1012.0
WLSH3_k127_4024538_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001143 273.0
WLSH3_k127_4024538_2 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000007055 160.0
WLSH3_k127_4024538_3 - - - - 0.000008518 51.0
WLSH3_k127_4075371_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 357.0
WLSH3_k127_4075371_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000001908 70.0
WLSH3_k127_4075371_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0002999 44.0
WLSH3_k127_4077864_0 integral membrane protein (DUF6 domain protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 391.0
WLSH3_k127_4077864_1 UDP-glucoronosyl and UDP-glucosyl transferase K16444 - 2.4.1.310 0.000000000000000000000000000000000000000009158 160.0
WLSH3_k127_4077864_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000001471 122.0
WLSH3_k127_41550_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 580.0
WLSH3_k127_41550_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000001241 229.0
WLSH3_k127_41550_2 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000006514 214.0
WLSH3_k127_4158907_0 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 338.0
WLSH3_k127_4158907_1 PFAM outer membrane porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 320.0
WLSH3_k127_4180235_0 TIGRFAM YD repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002601 232.0
WLSH3_k127_4180235_1 RHS Repeat - - - 0.0000000000000000000000000000007146 127.0
WLSH3_k127_420917_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 572.0
WLSH3_k127_420917_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 428.0
WLSH3_k127_420917_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000006063 228.0
WLSH3_k127_420917_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000002005 210.0
WLSH3_k127_4234992_0 molybdopterin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 442.0
WLSH3_k127_4234992_1 nuclease activity K06218 - - 0.00000000000000000000000003399 110.0
WLSH3_k127_4248547_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.898e-198 619.0
WLSH3_k127_4250522_0 Protein kinase, ABC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 370.0
WLSH3_k127_4250522_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000007941 139.0
WLSH3_k127_427632_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 503.0
WLSH3_k127_427632_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000009848 197.0
WLSH3_k127_4321214_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.73e-235 736.0
WLSH3_k127_4321214_1 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007083 246.0
WLSH3_k127_4321214_2 Rhodanese Homology Domain - - - 0.0000000000000000000000000000001463 128.0
WLSH3_k127_4321214_3 - - - - 0.000000000000000000000000000000854 125.0
WLSH3_k127_4325417_0 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 482.0
WLSH3_k127_432565_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 594.0
WLSH3_k127_432565_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 299.0
WLSH3_k127_432565_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001242 253.0
WLSH3_k127_432565_3 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000591 234.0
WLSH3_k127_432565_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000002748 116.0
WLSH3_k127_4370209_0 acid membrane antigen A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 358.0
WLSH3_k127_4370209_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000004001 141.0
WLSH3_k127_4375139_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 520.0
WLSH3_k127_4375139_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 464.0
WLSH3_k127_4375139_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000007101 201.0
WLSH3_k127_4375139_3 - - - - 0.000000000000000000000000000000000000000000000000001033 189.0
WLSH3_k127_4375139_4 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000002154 88.0
WLSH3_k127_4383845_0 potassium channel protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 376.0
WLSH3_k127_4383845_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 350.0
WLSH3_k127_4383845_2 TrkA-N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002499 228.0
WLSH3_k127_4425615_0 Belongs to the GARS family K01945 - 6.3.4.13 1.242e-194 611.0
WLSH3_k127_4474944_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 389.0
WLSH3_k127_4474944_1 Transcriptional regulator, ModE family K02019 - - 0.0000000000000000000000000000006457 123.0
WLSH3_k127_4503408_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000003523 168.0
WLSH3_k127_4503408_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000007826 117.0
WLSH3_k127_4503408_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000001335 81.0
WLSH3_k127_4503408_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000005154 62.0
WLSH3_k127_4505638_0 SNF2 family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 305.0
WLSH3_k127_4527674_0 Ribbon-helix-helix domain - - - 0.000000000000000000000002671 104.0
WLSH3_k127_4527674_1 nuclease activity K06218 - - 0.000000000000000001956 87.0
WLSH3_k127_4527674_2 - - - - 0.0001754 45.0
WLSH3_k127_4532935_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.701e-221 689.0
WLSH3_k127_4532935_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000872 512.0
WLSH3_k127_4532935_2 Heavy-metal-associated domain - - - 0.0000000000000000000000000000007299 124.0
WLSH3_k127_4532935_3 2-oxoglutarate acceptor oxidoreductase K00176 - 1.2.7.3 0.000000000000000001267 85.0
WLSH3_k127_4639157_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 514.0
WLSH3_k127_4641999_0 DEAD DEAH box helicase K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 559.0
WLSH3_k127_4641999_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 303.0
WLSH3_k127_4701262_0 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 449.0
WLSH3_k127_4732806_0 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 450.0
WLSH3_k127_4732806_1 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002574 282.0
WLSH3_k127_4732806_2 - - - - 0.000000000000000000000000000000000000000172 152.0
WLSH3_k127_4732806_3 Tetratricopeptide repeat - - - 0.00003204 55.0
WLSH3_k127_4733366_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1204.0
WLSH3_k127_4733366_1 (EAL) domain protein - - - 0.0000000000000000004866 91.0
WLSH3_k127_4768950_0 arginine decarboxylase K01585 - 4.1.1.19 3.685e-308 949.0
WLSH3_k127_4768950_1 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 319.0
WLSH3_k127_4772357_0 MORN repeat variant - - - 0.000000000000000000000000000000000000000000000000000000002067 211.0
WLSH3_k127_4772357_1 ORF6N domain - - - 0.000000000000000000000000000000000000000000000000000000005758 203.0
WLSH3_k127_4772357_2 Abi-like protein - - - 0.000000000000000000000000000000004189 134.0
WLSH3_k127_4772357_3 - - - - 0.00000000000000001916 91.0
WLSH3_k127_4772357_4 HTH domain - - - 0.00000003111 57.0
WLSH3_k127_4809338_0 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 319.0
WLSH3_k127_4809338_1 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000002178 169.0
WLSH3_k127_4809338_2 hydrolase K01501 - 3.5.5.1 0.000000000000000000000000000000000000000000003489 165.0
WLSH3_k127_4809338_3 - - - - 0.000000000000000000000000000000000000000001266 159.0
WLSH3_k127_4813979_0 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 390.0
WLSH3_k127_4813979_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000006808 210.0
WLSH3_k127_483641_0 Efflux transporter, outer membrane factor lipoprotein, NodT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003216 263.0
WLSH3_k127_4861824_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.43e-320 989.0
WLSH3_k127_4861824_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 531.0
WLSH3_k127_4861824_2 riboflavin synthase alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 312.0
WLSH3_k127_4861824_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002601 261.0
WLSH3_k127_4861824_4 DUF218 domain K03748 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000001686 205.0
WLSH3_k127_4861824_5 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000008855 165.0
WLSH3_k127_4861824_6 Cupin domain K11312 - - 0.000000000000000000000000002974 113.0
WLSH3_k127_4861824_7 - - - - 0.00000000000000000000002706 109.0
WLSH3_k127_4869502_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 5.612e-247 772.0
WLSH3_k127_4869502_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 565.0
WLSH3_k127_4869502_2 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 479.0
WLSH3_k127_4869502_3 COG0841 Cation multidrug efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 386.0
WLSH3_k127_4869502_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001525 274.0
WLSH3_k127_4915029_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 335.0
WLSH3_k127_4915029_1 COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000007096 100.0
WLSH3_k127_4957281_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000003433 108.0
WLSH3_k127_4957281_1 Domain of unknown function (DUF4116) - - - 0.0000000000000008141 87.0
WLSH3_k127_4958322_0 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000000006124 165.0
WLSH3_k127_4969327_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 488.0
WLSH3_k127_4969327_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 320.0
WLSH3_k127_4973750_0 threonine synthase K01733 - 4.2.3.1 1.562e-199 628.0
WLSH3_k127_4973750_1 ABC transporter, ATP-binding protein K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 379.0
WLSH3_k127_4973750_2 Lysin motif - - - 0.00000000000000000000000000000000000000000000001101 181.0
WLSH3_k127_5006735_0 TonB dependent receptor K02014 - - 1.117e-259 807.0
WLSH3_k127_5006735_1 PBP superfamily domain K05772 - - 0.00000000000000000000001325 107.0
WLSH3_k127_5056071_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 392.0
WLSH3_k127_5056071_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
WLSH3_k127_5056071_2 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000004406 187.0
WLSH3_k127_5056071_3 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000972 80.0
WLSH3_k127_5079512_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 308.0
WLSH3_k127_5079512_1 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000469 258.0
WLSH3_k127_5105857_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 555.0
WLSH3_k127_5105857_1 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000001984 109.0
WLSH3_k127_5105857_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000002616 78.0
WLSH3_k127_5120178_0 Glycosyl hydrolase family 3 K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 432.0
WLSH3_k127_5120178_1 DNA processing protein K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002603 261.0
WLSH3_k127_5120178_2 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000006193 182.0
WLSH3_k127_5128215_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1083.0
WLSH3_k127_5128215_1 integral membrane protein - - - 0.0000000000061 68.0
WLSH3_k127_5132371_0 PFAM NADH ubiquinone oxidoreductase, 20 Kd subunit K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 399.0
WLSH3_k127_5132371_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 270.0
WLSH3_k127_5132371_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000009856 216.0
WLSH3_k127_5132371_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000001738 130.0
WLSH3_k127_5167795_0 HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 308.0
WLSH3_k127_5167795_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001288 244.0
WLSH3_k127_5167795_2 HI0933 family K07007 - - 0.000000000000000000000000000000000004019 142.0
WLSH3_k127_5169071_0 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 470.0
WLSH3_k127_5169071_1 integral membrane protein (DUF6 domain protein) - - - 0.0000000000000000000000000001001 115.0
WLSH3_k127_5169071_2 - - - - 0.00000007305 55.0
WLSH3_k127_5185472_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 548.0
WLSH3_k127_5315836_0 ABC-type multidrug transport system ATPase and permease K06148 - - 5e-222 702.0
WLSH3_k127_5315836_1 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 306.0
WLSH3_k127_5315836_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000009195 90.0
WLSH3_k127_5315836_3 Methylenetetrahydrofolate reductase - - - 0.00000003488 55.0
WLSH3_k127_536167_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 574.0
WLSH3_k127_536167_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 539.0
WLSH3_k127_536167_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 299.0
WLSH3_k127_536167_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000003211 188.0
WLSH3_k127_537859_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 578.0
WLSH3_k127_537859_1 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000006244 150.0
WLSH3_k127_5390032_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 2.2e-213 666.0
WLSH3_k127_5390032_1 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 578.0
WLSH3_k127_5390032_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 556.0
WLSH3_k127_5390032_3 fumarate reductase, iron-sulfur protein K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000008963 246.0
WLSH3_k127_5390032_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000001276 122.0
WLSH3_k127_5390032_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000003295 63.0
WLSH3_k127_5407562_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 396.0
WLSH3_k127_5407562_1 Belongs to the TtcA family K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009097 267.0
WLSH3_k127_5407562_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000007656 263.0
WLSH3_k127_5469881_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1708.0
WLSH3_k127_5469881_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000001363 226.0
WLSH3_k127_5470862_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 407.0
WLSH3_k127_5470862_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 340.0
WLSH3_k127_5470862_2 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
WLSH3_k127_5470862_3 lipid a biosynthesis K02517 - 2.3.1.241 0.00000000000002366 77.0
WLSH3_k127_5499633_0 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 390.0
WLSH3_k127_5499633_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000001347 152.0
WLSH3_k127_5499633_2 - - - - 0.0005303 44.0
WLSH3_k127_551397_0 Belongs to the ClpA ClpB family K03694,K03695 - - 1.609e-315 975.0
WLSH3_k127_551397_1 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 403.0
WLSH3_k127_551397_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
WLSH3_k127_5524559_0 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 578.0
WLSH3_k127_5524559_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000006418 195.0
WLSH3_k127_5529233_0 amino acid carrier protein K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 592.0
WLSH3_k127_556564_0 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 437.0
WLSH3_k127_556564_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 318.0
WLSH3_k127_556564_2 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000005078 129.0
WLSH3_k127_5566859_0 ABC transporter, ATP-binding protein K01990,K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 389.0
WLSH3_k127_5566859_1 tigr02757 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 300.0
WLSH3_k127_5566859_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005118 256.0
WLSH3_k127_5566859_3 ATPase or kinase K06925 - - 0.000000000000000000000000000000000000005326 149.0
WLSH3_k127_5566859_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000258 138.0
WLSH3_k127_5566859_5 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000006283 134.0
WLSH3_k127_5585992_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 586.0
WLSH3_k127_5585992_1 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000001596 109.0
WLSH3_k127_5648375_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 522.0
WLSH3_k127_5648375_1 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000001047 143.0
WLSH3_k127_5785287_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 303.0
WLSH3_k127_5785287_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 287.0
WLSH3_k127_5799103_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.177e-224 708.0
WLSH3_k127_5821533_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 9.625e-219 688.0
WLSH3_k127_5857295_0 argininosuccinate lyase K01755 - 4.3.2.1 3.189e-232 725.0
WLSH3_k127_5910934_0 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 351.0
WLSH3_k127_5910934_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 339.0
WLSH3_k127_5910934_2 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000008283 134.0
WLSH3_k127_5910934_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000003234 83.0
WLSH3_k127_5978171_0 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001871 271.0
WLSH3_k127_5978171_2 Prepilin-type N-terminal cleavage methylation domain - - - 0.00000000002167 68.0
WLSH3_k127_5978447_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 458.0
WLSH3_k127_5978447_1 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000007457 211.0
WLSH3_k127_5978447_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000004924 205.0
WLSH3_k127_5978447_3 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000102 172.0
WLSH3_k127_5978447_4 S4 domain protein - - - 0.0000000000000000000000000000006324 123.0
WLSH3_k127_5978447_5 Sel1-like repeats. - - - 0.0000001558 56.0
WLSH3_k127_597944_0 hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000004995 214.0
WLSH3_k127_597944_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000001454 190.0
WLSH3_k127_597944_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000007913 76.0
WLSH3_k127_5991200_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 376.0
WLSH3_k127_5991200_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000005406 223.0
WLSH3_k127_5991200_2 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000001095 132.0
WLSH3_k127_5991200_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000009808 116.0
WLSH3_k127_601678_0 Long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 464.0
WLSH3_k127_601678_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 455.0
WLSH3_k127_601678_2 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 444.0
WLSH3_k127_601678_3 phosphoenolpyruvate-dependent sugar phosphotransferase system K02777,K02802,K02803,K02804,K20107,K20108 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006950,GO:0006974,GO:0008150,GO:0008643,GO:0009401,GO:0009987,GO:0015144,GO:0015764,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0033554,GO:0034219,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0071702,GO:0090563,GO:0090586,GO:1901264 2.7.1.193,2.7.1.208 0.000000000000000000000000000000000000000000004663 168.0
WLSH3_k127_6016927_0 TIGRFAM RHS repeat-associated core domain-containing protein, YD repeat protein - - - 0.0000000000000000000000000000000000000000000000004017 189.0
WLSH3_k127_6048915_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000271 191.0
WLSH3_k127_6048915_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000003275 76.0
WLSH3_k127_6048915_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000001299 70.0
WLSH3_k127_6152606_0 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 298.0
WLSH3_k127_6152606_1 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000378 156.0
WLSH3_k127_6152606_2 thioesterase K07107 - - 0.00000000000000000000000000000003709 128.0
WLSH3_k127_6157920_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.36e-200 628.0
WLSH3_k127_6196713_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 5.664e-203 642.0
WLSH3_k127_6196713_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000008185 71.0
WLSH3_k127_6199798_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 482.0
WLSH3_k127_6199798_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 354.0
WLSH3_k127_6199798_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000009667 78.0
WLSH3_k127_6199798_3 AcrB/AcrD/AcrF family - - - 0.00000000003951 64.0
WLSH3_k127_620991_0 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000005167 197.0
WLSH3_k127_620991_1 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000013 193.0
WLSH3_k127_620991_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000001335 161.0
WLSH3_k127_620991_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000002898 143.0
WLSH3_k127_620991_4 RHS Repeat - - - 0.0002017 51.0
WLSH3_k127_6238367_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 482.0
WLSH3_k127_6238367_1 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000002667 189.0
WLSH3_k127_6238367_2 flagellar biosynthesis K02404 - - 0.000000000000000000000000000000000000000000000000003413 196.0
WLSH3_k127_6246791_0 Cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 325.0
WLSH3_k127_6246791_1 Dihaem cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000002936 204.0
WLSH3_k127_6246791_2 Cytochrome C protein - - - 0.000000000000000000000000000000000000000000002482 168.0
WLSH3_k127_6246791_3 - - - - 0.000000000000000000008475 96.0
WLSH3_k127_6246791_4 Chemotaxis protein CheY K02483 - - 0.0000000000001138 72.0
WLSH3_k127_6265448_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 501.0
WLSH3_k127_6265448_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 366.0
WLSH3_k127_6265448_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000002188 233.0
WLSH3_k127_6265448_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000004136 223.0
WLSH3_k127_6265448_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000008257 214.0
WLSH3_k127_6265448_5 ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000001564 204.0
WLSH3_k127_6265448_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000000009893 151.0
WLSH3_k127_6265448_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002944 73.0
WLSH3_k127_6265448_8 Rhodanese Homology Domain - - - 0.00000000002354 65.0
WLSH3_k127_6291529_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 346.0
WLSH3_k127_6291529_1 WYL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006579 273.0
WLSH3_k127_6294743_0 anthranilate synthase component K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 574.0
WLSH3_k127_6294743_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 343.0
WLSH3_k127_6294743_2 response regulator K02483 - - 0.00000000000000000000000000000005394 125.0
WLSH3_k127_6294743_3 peptidoglycan binding K02343,K03642,K03749 - 2.7.7.7 0.0000000000002365 78.0
WLSH3_k127_6329011_0 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 374.0
WLSH3_k127_6329011_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000006249 125.0
WLSH3_k127_6329011_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000397 49.0
WLSH3_k127_6399191_0 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 289.0
WLSH3_k127_6399191_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000002431 255.0
WLSH3_k127_6399191_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000009631 201.0
WLSH3_k127_6400018_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 458.0
WLSH3_k127_6400018_1 Sel1-like repeats. - - - 0.0000000002287 63.0
WLSH3_k127_6406522_0 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000005707 138.0
WLSH3_k127_6414473_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.096e-218 681.0
WLSH3_k127_6414473_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005248 244.0
WLSH3_k127_6445528_0 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 522.0
WLSH3_k127_6445528_1 of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001058 251.0
WLSH3_k127_6462648_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 421.0
WLSH3_k127_6462648_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001141 274.0
WLSH3_k127_6462648_2 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000003209 248.0
WLSH3_k127_6470884_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 3.207e-194 610.0
WLSH3_k127_6470884_1 TPM domain K08988 - - 0.000000000000000000000000000000000000000000000000000000000006245 213.0
WLSH3_k127_6479540_0 ATP citrate synthase K15230 - 2.3.3.8 0.0 1047.0
WLSH3_k127_6479540_1 ATP citrate lyase citrate-binding - - - 5.837e-255 790.0
WLSH3_k127_6479540_2 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000001216 237.0
WLSH3_k127_6479540_3 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001149 246.0
WLSH3_k127_6479540_4 Tfp pilus assembly protein FimT - - - 0.00000000000000000000000000000000000000000000000000000493 197.0
WLSH3_k127_6482816_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 304.0
WLSH3_k127_6482816_1 Ankyrin repeat K06867 - - 0.000000000000000000000000000000000000009521 151.0
WLSH3_k127_6483259_0 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
WLSH3_k127_6483259_1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000000000002815 125.0
WLSH3_k127_6483259_2 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000004942 117.0
WLSH3_k127_6483259_3 - - - - 0.0000000000000000000008998 102.0
WLSH3_k127_6483259_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000006931 63.0
WLSH3_k127_6539128_0 Protein of unknown function (DUF2628) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002003 121.0
WLSH3_k127_6573116_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000004382 228.0
WLSH3_k127_6573116_1 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000007629 206.0
WLSH3_k127_6573116_2 dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000003285 181.0
WLSH3_k127_6573116_3 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000008825 117.0
WLSH3_k127_6573116_4 Belongs to the UPF0251 family - - - 0.000000000000000009357 86.0
WLSH3_k127_6573116_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000001449 50.0
WLSH3_k127_6587954_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 360.0
WLSH3_k127_6587954_1 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000756 108.0
WLSH3_k127_6591911_0 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000006436 157.0
WLSH3_k127_6591911_1 - - - - 0.0000000000000000000000000000000007108 136.0
WLSH3_k127_6591911_2 - - - - 0.000000000000000000009099 98.0
WLSH3_k127_6591911_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000002917 86.0
WLSH3_k127_6591911_4 carboxylic ester hydrolase activity - - - 0.00000000003419 66.0
WLSH3_k127_6591911_5 COG1943 Transposase and inactivated derivatives - - - 0.0000005859 51.0
WLSH3_k127_6602487_0 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 476.0
WLSH3_k127_6602487_1 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 440.0
WLSH3_k127_6602487_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000007104 180.0
WLSH3_k127_6602487_3 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000000000002777 179.0
WLSH3_k127_6612764_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 309.0
WLSH3_k127_6612764_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000008208 205.0
WLSH3_k127_6635208_0 TonB-dependent copper receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
WLSH3_k127_6635208_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000092 77.0
WLSH3_k127_6638162_0 Aminotransferase K14261 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 333.0
WLSH3_k127_6638162_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 311.0
WLSH3_k127_6638162_2 Protein conserved in bacteria - - - 0.000000000000000243 89.0
WLSH3_k127_6638162_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000006654 79.0
WLSH3_k127_6690942_0 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 417.0
WLSH3_k127_6690942_1 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.00000000000000000000000000000000001438 138.0
WLSH3_k127_6705329_0 Peptidase, M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 387.0
WLSH3_k127_6705329_1 ATP-dependent DNA helicase K03655 - 3.6.4.12 0.00000001143 59.0
WLSH3_k127_6742241_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 619.0
WLSH3_k127_6742241_1 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 476.0
WLSH3_k127_6742241_10 TIGRFAM YD repeat protein - - - 0.00000000003951 64.0
WLSH3_k127_6742241_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 376.0
WLSH3_k127_6742241_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 351.0
WLSH3_k127_6742241_4 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001891 268.0
WLSH3_k127_6742241_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000002477 203.0
WLSH3_k127_6742241_6 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000000000000000000003516 181.0
WLSH3_k127_6742241_7 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000000000119 167.0
WLSH3_k127_6742241_8 Helix-turn-helix domain - - - 0.00000000000000000000000000000000005967 135.0
WLSH3_k127_6742241_9 Sel1-like repeats. - - - 0.0000000000000001112 91.0
WLSH3_k127_6778108_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 341.0
WLSH3_k127_6778108_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 330.0
WLSH3_k127_6778108_2 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000002368 229.0
WLSH3_k127_6778108_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000004051 158.0
WLSH3_k127_678067_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005396 252.0
WLSH3_k127_678067_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003042 229.0
WLSH3_k127_678067_2 TonB-dependent copper receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000005021 219.0
WLSH3_k127_678067_3 reductase K00059 - 1.1.1.100 0.0000000000000000007449 86.0
WLSH3_k127_678261_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.566e-258 801.0
WLSH3_k127_678261_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000887 278.0
WLSH3_k127_6784249_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 559.0
WLSH3_k127_6784249_1 Heterodisulfide reductase subunit B K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 496.0
WLSH3_k127_6784249_2 McrBC 5-methylcytosine restriction system component K19147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 421.0
WLSH3_k127_6784249_3 - - - - 0.000000000000000000000000000000000000000000000851 169.0
WLSH3_k127_6835220_0 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 492.0
WLSH3_k127_6835220_1 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005993 271.0
WLSH3_k127_6835220_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002598 220.0
WLSH3_k127_68678_0 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 461.0
WLSH3_k127_68678_1 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 333.0
WLSH3_k127_68678_2 Sulfate permease K03321 - - 0.000000000000000000000000000000000000000000000000007092 183.0
WLSH3_k127_6883780_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 5.191e-203 636.0
WLSH3_k127_6889982_0 Oligosaccharide transferase K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 621.0
WLSH3_k127_6889982_1 Polysaccharide biosynthesis protein K15912 - 4.2.1.135 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 305.0
WLSH3_k127_6891758_0 - - - - 0.0000000000000000000000000000000000000000000000000000003325 195.0
WLSH3_k127_6891758_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000007793 105.0
WLSH3_k127_6921931_0 Cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 607.0
WLSH3_k127_6921931_1 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 557.0
WLSH3_k127_6921931_2 Polysulphide reductase NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
WLSH3_k127_6921931_3 - - - - 0.0000000000000000002499 89.0
WLSH3_k127_6926591_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.114e-201 633.0
WLSH3_k127_6926591_1 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 348.0
WLSH3_k127_6926591_2 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000000000007006 159.0
WLSH3_k127_6970113_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 556.0
WLSH3_k127_6970113_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000293 242.0
WLSH3_k127_6970113_2 Tetratricopeptide repeat - - - 0.000000000000000007927 89.0
WLSH3_k127_6970113_3 Tetratricopeptide repeat - - - 0.0000000000000001791 84.0
WLSH3_k127_6970113_4 tetratricopeptide repeat - - - 0.000000000004276 71.0
WLSH3_k127_6970284_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 330.0
WLSH3_k127_6970284_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000001464 212.0
WLSH3_k127_699671_0 Protein of unknown function (DUF1566) - - - 0.0001023 50.0
WLSH3_k127_7006678_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 4.058e-200 628.0
WLSH3_k127_7006678_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000000000000000000000001375 200.0
WLSH3_k127_7006678_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000009789 161.0
WLSH3_k127_7006678_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000004873 79.0
WLSH3_k127_7022215_0 4Fe-4S ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
WLSH3_k127_7022215_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000002808 158.0
WLSH3_k127_704345_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.0 1064.0
WLSH3_k127_704345_1 Polysulphide reductase NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000005845 220.0
WLSH3_k127_704345_2 molybdopterin oxidoreductase - - - 0.0000000000000000000000000000000000003458 141.0
WLSH3_k127_704345_3 molybdopterin oxidoreductase - - - 0.0000000000000000000000000000000000213 139.0
WLSH3_k127_7055718_0 lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 359.0
WLSH3_k127_7083682_0 AAA domain K07133 - - 3.004e-216 676.0
WLSH3_k127_7087853_0 nuclease activity K06218 - - 0.0000000000000000000000000001252 116.0
WLSH3_k127_7087853_1 - - - - 0.00000000000000000000000000449 119.0
WLSH3_k127_7147065_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 408.0
WLSH3_k127_7147065_1 permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000201 223.0
WLSH3_k127_7150032_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - 0.0000000000000000000000000000000000000000000000003128 190.0
WLSH3_k127_7150402_0 PFAM Cytochrome c, class I - - - 1.319e-207 654.0
WLSH3_k127_7150402_1 Belongs to the UPF0246 family K09861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006281 265.0
WLSH3_k127_7150402_2 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000000000000007755 168.0
WLSH3_k127_7150402_3 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000608 136.0
WLSH3_k127_7150402_4 - - - - 0.00000000000000000000000000000001547 131.0
WLSH3_k127_7150402_5 phage repressor - - - 0.00000000002754 63.0
WLSH3_k127_7152728_0 Belongs to the CarB family K01955 - 6.3.5.5 1.57e-272 842.0
WLSH3_k127_7155948_0 Cytochrome c oxidase accessory protein - - - 4.63e-219 686.0
WLSH3_k127_7155948_1 PFAM Resolvase, N terminal domain - - - 0.00000000000000000000000000000000000000000000000001169 187.0
WLSH3_k127_7160781_0 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 308.0
WLSH3_k127_7160781_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000165 197.0
WLSH3_k127_7162371_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 546.0
WLSH3_k127_7162371_1 Radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 442.0
WLSH3_k127_7162371_2 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 331.0
WLSH3_k127_7162371_3 Belongs to the aldehyde dehydrogenase family - - - 0.000000000000000000000000000000006662 130.0
WLSH3_k127_7162371_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000001711 55.0
WLSH3_k127_71803_0 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 1.78e-214 670.0
WLSH3_k127_71803_1 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001427 274.0
WLSH3_k127_7237030_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007549 254.0
WLSH3_k127_7237030_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000005274 207.0
WLSH3_k127_7238967_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 5.341e-220 689.0
WLSH3_k127_7240026_0 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 443.0
WLSH3_k127_7240026_1 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 441.0
WLSH3_k127_7240026_2 - - - - 0.000000000000000000000000000000000000000352 151.0
WLSH3_k127_7249829_0 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004232 276.0
WLSH3_k127_7249829_1 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000001737 198.0
WLSH3_k127_7249829_2 Heavy-metal-associated domain K08364 - - 0.0000000000000000000004238 99.0
WLSH3_k127_7276206_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 5.375e-213 664.0
WLSH3_k127_7276206_1 domain protein K09944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006108 462.0
WLSH3_k127_7276206_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 318.0
WLSH3_k127_7276206_3 Domain of unknown function (DUF386) - - - 0.000000000000000000000000000000000000000000000000000002063 194.0
WLSH3_k127_7276206_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000001312 120.0
WLSH3_k127_7276206_5 - - - - 0.00000000004237 65.0
WLSH3_k127_7276206_6 Pfam:Pyridox_oxidase - - - 0.0001847 45.0
WLSH3_k127_7287027_0 Membrane protease subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 416.0
WLSH3_k127_7287027_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000004755 200.0
WLSH3_k127_7287027_2 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000000000000000000004156 176.0
WLSH3_k127_7340746_0 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 436.0
WLSH3_k127_7340746_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000006897 112.0
WLSH3_k127_7345010_0 TIGRFAM YD repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000002738 210.0
WLSH3_k127_7389918_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 615.0
WLSH3_k127_7389918_1 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000000000000000009412 180.0
WLSH3_k127_7389918_2 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.0000000000000000000001078 110.0
WLSH3_k127_7395629_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 5.157e-198 620.0
WLSH3_k127_7395629_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006452 281.0
WLSH3_k127_7395629_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000003195 222.0
WLSH3_k127_7397993_0 ribosomal protein S1 K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 557.0
WLSH3_k127_7399054_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 342.0
WLSH3_k127_7399054_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000001708 127.0
WLSH3_k127_7399054_2 lytic transglycosylase activity - - - 0.000000000000000000000000006894 117.0
WLSH3_k127_7399054_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.0000000000004662 70.0
WLSH3_k127_7404732_0 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 445.0
WLSH3_k127_7425713_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 570.0
WLSH3_k127_7425713_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 376.0
WLSH3_k127_7425713_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000244 269.0
WLSH3_k127_7425713_3 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000236 128.0
WLSH3_k127_7425713_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000002911 108.0
WLSH3_k127_7426856_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 404.0
WLSH3_k127_7426856_1 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 375.0
WLSH3_k127_7426856_2 Peptidase family M48 - - - 0.000000000000000000000000000000000005541 145.0
WLSH3_k127_7435376_0 Low-potential electron donor to a number of redox enzymes K03839 - - 0.00000000000000000000000000000000000000000000000000000000000000000002629 235.0
WLSH3_k127_7435376_1 Nitrogen fixation protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003048 231.0
WLSH3_k127_7435376_2 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000009098 198.0
WLSH3_k127_7435376_3 peptidyl-prolyl cis-trans isomerase activity K02597,K07533 - 5.2.1.8 0.0000000000000000000000000000000000000000000003609 169.0
WLSH3_k127_7435376_4 Ferredoxin - - - 0.000000000000000000000000000000000000000000002966 166.0
WLSH3_k127_7435376_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000004809 132.0
WLSH3_k127_7435376_6 Nitrogen fixation protein NifW K02595 - - 0.00000000000000000000000000000006671 127.0
WLSH3_k127_7435376_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000009689 103.0
WLSH3_k127_7435376_8 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.0000000000000003869 78.0
WLSH3_k127_7489953_0 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000917 243.0
WLSH3_k127_7489953_1 ATP-dependent CLP protease ATP-binding subunit K03694 - - 0.000000000000000000000000000000000000000000000004029 178.0
WLSH3_k127_7489953_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000003342 127.0
WLSH3_k127_7493837_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 7.049e-194 607.0
WLSH3_k127_7493837_1 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 318.0
WLSH3_k127_7493837_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
WLSH3_k127_749732_0 potassium channel protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 438.0
WLSH3_k127_7520957_0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000002803 176.0
WLSH3_k127_7520957_1 Protein of unknown function (DUF493) - - - 0.0000000000000000000000000009088 114.0
WLSH3_k127_7520957_2 bacterial-type proximal promoter sequence-specific DNA binding K07473 - - 0.000000000000000000000000005796 112.0
WLSH3_k127_7520957_3 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034655,GO:0042221,GO:0042710,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043565,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044010,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044764,GO:0044877,GO:0046483,GO:0046677,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - 0.0000000000000005323 81.0
WLSH3_k127_7520957_4 AAA domain, putative AbiEii toxin, Type IV TA system K06926,K07459 - - 0.000007389 48.0
WLSH3_k127_7537768_0 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 302.0
WLSH3_k127_7537768_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 293.0
WLSH3_k127_7537768_2 acetyltransferase K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001215 236.0
WLSH3_k127_7537768_3 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000001896 207.0
WLSH3_k127_7537768_4 lipopolysaccharide binding K09774 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0009279,GO:0010876,GO:0015920,GO:0016020,GO:0017089,GO:0019867,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044462,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.00000000000000000000000000001787 123.0
WLSH3_k127_7537768_5 - - - - 0.000000000001068 74.0
WLSH3_k127_7537768_6 penicillin-binding protein K05515 - 3.4.16.4 0.00000113 52.0
WLSH3_k127_7537768_7 hmm pf06835 - - - 0.00001639 54.0
WLSH3_k127_7537768_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0006343 43.0
WLSH3_k127_7547173_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 297.0
WLSH3_k127_7547173_1 Phosphotransferase enzyme family K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000001068 89.0
WLSH3_k127_75534_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.774e-288 892.0
WLSH3_k127_75534_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000006807 128.0
WLSH3_k127_7610085_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004458 277.0
WLSH3_k127_7610085_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001325 278.0
WLSH3_k127_7610085_2 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000002761 123.0
WLSH3_k127_7644482_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 342.0
WLSH3_k127_7644482_1 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 340.0
WLSH3_k127_7644482_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 331.0
WLSH3_k127_7644482_3 PFAM NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000001745 171.0
WLSH3_k127_7644482_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000008765 145.0
WLSH3_k127_7653042_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.389e-245 769.0
WLSH3_k127_7653042_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 377.0
WLSH3_k127_7653042_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002908 255.0
WLSH3_k127_7653042_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000005569 128.0
WLSH3_k127_7653042_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000002489 86.0
WLSH3_k127_7653042_5 PFAM Resolvase, N-terminal - - - 0.000001086 50.0
WLSH3_k127_7763148_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 411.0
WLSH3_k127_7763148_2 toxin-antitoxin pair type II binding K06218,K18923 - - 0.00000000000000004771 82.0
WLSH3_k127_7833969_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 420.0
WLSH3_k127_7833969_1 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000002929 129.0
WLSH3_k127_7848330_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1049.0
WLSH3_k127_7848330_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 459.0
WLSH3_k127_7848330_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 357.0
WLSH3_k127_7848330_3 COG1214 Inactive homolog of metal-dependent proteases - - - 0.0000000000000000000000000000000002413 137.0
WLSH3_k127_7848330_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000001546 85.0
WLSH3_k127_7848330_5 nucleic-acid-binding protein implicated in transcription termination - - - 0.0000000000000002594 81.0
WLSH3_k127_7884028_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.098e-257 796.0
WLSH3_k127_7884028_1 Pseudouridine synthase K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
WLSH3_k127_7884028_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000002936 207.0
WLSH3_k127_7884257_0 Lysozyme inhibitor LprI - - - 0.0000000000000000000000000000000000003225 144.0
WLSH3_k127_7916171_0 Histidine kinase - - - 6.007e-197 633.0
WLSH3_k127_7916171_1 Histidine kinase K07676,K10715,K20976 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009927,GO:0009987,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0031224,GO:0031226,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000008503 117.0
WLSH3_k127_7947241_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.278e-207 649.0
WLSH3_k127_7947241_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 450.0
WLSH3_k127_7947241_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 409.0
WLSH3_k127_7947241_3 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000006212 151.0
WLSH3_k127_7947241_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000003253 59.0
WLSH3_k127_7957664_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 537.0
WLSH3_k127_7957664_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 317.0
WLSH3_k127_7965515_0 DNA mismatch repair enzyme MutH - - - 0.000000000000000000000000002066 112.0
WLSH3_k127_7965515_1 conserved protein (DUF2196) - - - 0.0000000000000000000001995 97.0
WLSH3_k127_7965515_2 peptidyl-tyrosine sulfation - - - 0.00000000000004164 79.0
WLSH3_k127_7970667_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 412.0
WLSH3_k127_7970667_1 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000001883 117.0
WLSH3_k127_8036886_0 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 321.0
WLSH3_k127_8036886_1 - - - - 0.000000000000000000000000000000000000000000000000000001482 205.0
WLSH3_k127_8118969_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.386e-220 689.0
WLSH3_k127_8118969_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 601.0
WLSH3_k127_8118969_2 protein conserved in bacteria K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 291.0
WLSH3_k127_8118969_3 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine - - - 0.000000000000000000000000000000000000000000000000000000000000002236 222.0
WLSH3_k127_8118969_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000005968 123.0
WLSH3_k127_8121756_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 568.0
WLSH3_k127_8121756_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 332.0
WLSH3_k127_8149567_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 592.0
WLSH3_k127_8149567_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 554.0
WLSH3_k127_8155655_0 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001999 263.0
WLSH3_k127_8161409_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 372.0
WLSH3_k127_8161409_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000009891 98.0
WLSH3_k127_8161409_2 PFAM TPR repeat-containing protein - - - 0.000000000000000000001091 102.0
WLSH3_k127_8163024_0 Prepilin-type N-terminal cleavage methylation domain - - - 0.0000000000000000000000000000001179 133.0
WLSH3_k127_8163024_1 general secretion pathway protein K02456,K02457,K02458,K10926,K10930,K10931 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840 - 0.00009637 49.0
WLSH3_k127_8192005_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000001213 257.0
WLSH3_k127_8206431_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 1.869e-267 841.0
WLSH3_k127_8206431_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.282e-226 707.0
WLSH3_k127_8223713_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 404.0
WLSH3_k127_8223713_1 ArsC family - - - 0.00000000000000000000000000000000000002067 147.0
WLSH3_k127_8228952_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 511.0
WLSH3_k127_8228952_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 308.0
WLSH3_k127_8228952_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001152 268.0
WLSH3_k127_8253613_0 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009228 259.0
WLSH3_k127_8253613_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000005066 227.0
WLSH3_k127_8253613_2 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000009699 71.0
WLSH3_k127_825785_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 516.0
WLSH3_k127_8273501_0 ATPase (AAA K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
WLSH3_k127_8307940_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0000000000000000000000000000000000000344 162.0
WLSH3_k127_8382249_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 421.0
WLSH3_k127_8382339_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 376.0
WLSH3_k127_8382339_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000005089 198.0
WLSH3_k127_8387776_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 495.0
WLSH3_k127_8387776_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 392.0
WLSH3_k127_8387776_10 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000000000006321 164.0
WLSH3_k127_8387776_11 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000001755 147.0
WLSH3_k127_8387776_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000001909 124.0
WLSH3_k127_8387776_13 ATPase (AAA K07133 - - 0.000000002091 60.0
WLSH3_k127_8387776_2 ribosomal protein L3 K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 324.0
WLSH3_k127_8387776_3 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 291.0
WLSH3_k127_8387776_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000001495 233.0
WLSH3_k127_8387776_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000003709 231.0
WLSH3_k127_8387776_6 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000004242 193.0
WLSH3_k127_8387776_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000001678 186.0
WLSH3_k127_8387776_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000003566 184.0
WLSH3_k127_8387776_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000001223 177.0
WLSH3_k127_8398080_0 oxidase subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 534.0
WLSH3_k127_8417667_0 Molecular chaperone. Has ATPase activity K04079 - - 3.152e-255 795.0
WLSH3_k127_8417667_1 Transglutaminase-like - - - 0.000000000005953 66.0
WLSH3_k127_8521819_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 539.0
WLSH3_k127_8521819_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 510.0
WLSH3_k127_8661232_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 399.0
WLSH3_k127_8661232_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000009399 175.0
WLSH3_k127_8687074_0 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 336.0
WLSH3_k127_8687074_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000001141 126.0
WLSH3_k127_8688637_0 ATPase (AAA - - - 3.556e-286 887.0
WLSH3_k127_8688637_1 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 401.0
WLSH3_k127_8688637_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000001554 120.0
WLSH3_k127_8692103_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 347.0
WLSH3_k127_8692103_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000003045 139.0
WLSH3_k127_8709372_0 type I restriction-modification system K03427 - 2.1.1.72 1.191e-291 899.0
WLSH3_k127_8709372_1 Virulence protein RhuM family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 447.0
WLSH3_k127_8709372_2 Type I restriction modification DNA specificity domain K01154,K03709 - 3.1.21.3 0.0000000000002911 72.0
WLSH3_k127_8710133_0 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 1.844e-219 691.0
WLSH3_k127_8710133_1 UPF0313 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 483.0
WLSH3_k127_8710133_2 Virulence protein RhuM family - - - 0.000000000000000000000000000000000005791 139.0
WLSH3_k127_8715321_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 574.0
WLSH3_k127_8715321_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 494.0
WLSH3_k127_8715321_2 COGs COG3786 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000004082 239.0
WLSH3_k127_8715321_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000315 161.0
WLSH3_k127_8715321_4 Protein of unknown function (DUF2892) - - - 0.000000000008874 66.0
WLSH3_k127_8727944_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 8.733e-195 612.0
WLSH3_k127_8733429_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.376e-302 936.0
WLSH3_k127_8734771_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 589.0
WLSH3_k127_8734771_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 508.0
WLSH3_k127_8734771_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 328.0
WLSH3_k127_8734771_3 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
WLSH3_k127_8734771_4 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000001812 226.0
WLSH3_k127_8758062_0 Potassium uptake protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 583.0
WLSH3_k127_8758062_1 uptake protein K03499 - - 0.00000000001471 65.0
WLSH3_k127_8782380_0 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 444.0
WLSH3_k127_8794079_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 424.0
WLSH3_k127_8794079_1 uracil phosphoribosyltransferase K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008205 268.0
WLSH3_k127_8794079_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000112 210.0
WLSH3_k127_8797666_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 464.0
WLSH3_k127_8797666_1 Lipopolysaccharide-assembly - - - 0.000000000000005392 77.0
WLSH3_k127_8800960_0 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000009791 241.0
WLSH3_k127_8800960_1 Nudix domain K08077 - 3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000006896 222.0
WLSH3_k127_8827458_0 phosphoribosyltransferase K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000002958 194.0
WLSH3_k127_8827458_1 - - - - 0.0000000000000000000000000009476 119.0
WLSH3_k127_8827458_2 Anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000005443 109.0
WLSH3_k127_8827458_3 Haloacid dehalogenase-like hydrolase - - - 0.00003679 52.0
WLSH3_k127_8855236_0 PFAM TrkA-N domain protein - - - 1.103e-194 621.0
WLSH3_k127_8855236_1 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 472.0
WLSH3_k127_8855236_2 Redox-active disulfide protein - - - 0.000000000000000000000000000009214 119.0
WLSH3_k127_8887078_0 Ethylbenzene dehydrogenase K17052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 334.0
WLSH3_k127_8887078_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005096 259.0
WLSH3_k127_8887078_2 Predicted nucleotidyltransferase K07074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004011 243.0
WLSH3_k127_8887078_3 4Fe-4S dicluster domain K17051 - - 0.00000000000000000000000000000000000000000000000000000000000000006294 224.0
WLSH3_k127_8887078_4 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000007623 212.0
WLSH3_k127_8887078_5 - - - - 0.00000000000000000000000000000002948 131.0
WLSH3_k127_8890800_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 460.0
WLSH3_k127_8890800_1 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 436.0
WLSH3_k127_8890800_2 Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000322 170.0
WLSH3_k127_8890800_3 chaperone-mediated protein folding - - - 0.000000000000000000006029 101.0
WLSH3_k127_8905316_0 Belongs to the DegT DnrJ EryC1 family K15910 - 2.6.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 589.0
WLSH3_k127_8905316_1 sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K15913 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.3.1.203 0.00000000000000000000000000000002324 128.0
WLSH3_k127_8918339_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 435.0
WLSH3_k127_8918339_1 acetolactate synthase K01653 - 2.2.1.6 0.000000000000000000000000000000000000000002888 156.0
WLSH3_k127_8918339_2 - - - - 0.0000000000000000003021 89.0
WLSH3_k127_8928668_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 391.0
WLSH3_k127_8928668_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000134 284.0
WLSH3_k127_894307_0 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 521.0
WLSH3_k127_894307_1 MORN repeat variant - - - 0.000000000000000000000000004393 115.0
WLSH3_k127_894307_2 Pfam:DUF1311 - - - 0.0000006146 59.0
WLSH3_k127_8962965_0 Initiator Replication protein - - - 0.00000000000000006876 92.0
WLSH3_k127_8963337_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 572.0
WLSH3_k127_8977640_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 617.0
WLSH3_k127_8981934_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 5.074e-312 958.0
WLSH3_k127_8981934_1 Nitrogenase protein alpha chain K02586 - 1.18.6.1 7.994e-279 858.0
WLSH3_k127_8981934_2 Abc transporter K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 325.0
WLSH3_k127_8985551_0 Belongs to the NifD NifK NifE NifN family K02592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 475.0
WLSH3_k127_8985551_1 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000000006521 179.0
WLSH3_k127_8992296_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 4.137e-233 724.0
WLSH3_k127_8992296_1 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000004017 190.0
WLSH3_k127_9047824_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.064e-288 890.0
WLSH3_k127_9047824_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 422.0
WLSH3_k127_9047824_2 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 376.0
WLSH3_k127_9047824_4 cytochrome c oxidase K00407 - - 0.000000000000000000000009307 102.0
WLSH3_k127_9047824_6 FixH - - - 0.00000006091 59.0
WLSH3_k127_9055527_0 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 406.0
WLSH3_k127_9055527_1 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000003881 187.0
WLSH3_k127_9055527_2 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000001486 166.0
WLSH3_k127_9058896_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 426.0
WLSH3_k127_9058896_1 PFAM dUTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006812 272.0
WLSH3_k127_9058896_2 - - - - 0.00000000000000000000000366 109.0
WLSH3_k127_9074774_0 Mur ligase middle domain K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 395.0
WLSH3_k127_9074774_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000105 164.0
WLSH3_k127_909098_0 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000001583 175.0
WLSH3_k127_909098_1 Addiction module toxin RelE StbE family - - - 0.0000000000000000000000000000006457 123.0
WLSH3_k127_909098_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000003413 110.0
WLSH3_k127_909098_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000004537 81.0
WLSH3_k127_9098790_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 488.0
WLSH3_k127_9098790_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000008733 115.0
WLSH3_k127_9129006_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 369.0
WLSH3_k127_9129006_1 dna polymerase iii K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 367.0
WLSH3_k127_9129006_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000003318 130.0
WLSH3_k127_9129006_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000008898 110.0
WLSH3_k127_9129006_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000004976 106.0
WLSH3_k127_9134533_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 314.0
WLSH3_k127_9134533_1 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000006178 207.0
WLSH3_k127_9186407_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 287.0
WLSH3_k127_9186407_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000005669 104.0
WLSH3_k127_9186407_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000002054 81.0
WLSH3_k127_9188816_0 Belongs to the peptidase M16 family - - - 2.836e-194 615.0
WLSH3_k127_9188816_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007558 487.0
WLSH3_k127_9188816_2 dehydrogenase K00076 - 1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 466.0
WLSH3_k127_9188816_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 447.0
WLSH3_k127_9188816_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 312.0
WLSH3_k127_9188816_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 286.0
WLSH3_k127_9188816_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000024 192.0
WLSH3_k127_9278519_0 glutamine synthetase K01915 - 6.3.1.2 8.82e-227 706.0
WLSH3_k127_9278519_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 322.0
WLSH3_k127_9410117_0 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004028 258.0
WLSH3_k127_9410117_1 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000003993 222.0
WLSH3_k127_9410117_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000004588 162.0
WLSH3_k127_9410117_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000001488 109.0
WLSH3_k127_9449205_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 470.0
WLSH3_k127_9449205_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 320.0
WLSH3_k127_9468316_0 COG2067 Long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000001357 123.0
WLSH3_k127_9501301_0 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 345.0
WLSH3_k127_9501301_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000003518 193.0
WLSH3_k127_9507846_0 Glycerol-3-phosphate dehydrogenase K11473 - - 3.754e-236 734.0
WLSH3_k127_9507846_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 391.0
WLSH3_k127_9512985_0 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009154 278.0
WLSH3_k127_9533486_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 466.0
WLSH3_k127_9533486_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000152 60.0
WLSH3_k127_9589908_0 uptake protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
WLSH3_k127_9589908_1 Rhodanese-like domain - - - 0.000000000000000000000000000000142 127.0
WLSH3_k127_9589908_2 Thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.0000001454 55.0
WLSH3_k127_9610627_0 Glycolate oxidase subunit K00104 - 1.1.3.15 2.138e-252 783.0
WLSH3_k127_9610627_1 peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 299.0
WLSH3_k127_9610627_2 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 261.0
WLSH3_k127_9610627_3 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000009255 220.0
WLSH3_k127_9611564_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 391.0
WLSH3_k127_9611564_1 Belongs to the 'phage' integrase family K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 372.0
WLSH3_k127_9611564_2 protein conserved in bacteria K09778 - - 0.00000000000000000000000000000000000000000000000000000000000002675 220.0
WLSH3_k127_9647302_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 449.0
WLSH3_k127_9647302_1 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000171 225.0
WLSH3_k127_9647302_2 - - - - 0.0000000000009558 73.0
WLSH3_k127_9669959_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 5.57e-200 628.0
WLSH3_k127_9689164_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 585.0
WLSH3_k127_9689164_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000007312 79.0
WLSH3_k127_9736874_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 496.0
WLSH3_k127_9736874_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 261.0
WLSH3_k127_9736874_2 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000002135 214.0
WLSH3_k127_9736874_3 of the HAD superfamily - - - 0.00004851 46.0
WLSH3_k127_9746397_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 1.149e-298 933.0
WLSH3_k127_9746397_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 1.246e-272 850.0
WLSH3_k127_9746397_2 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 1.07e-217 679.0
WLSH3_k127_9746397_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 504.0
WLSH3_k127_9746397_4 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 482.0
WLSH3_k127_9746397_5 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.00000000000000000000000000000001445 128.0
WLSH3_k127_9771970_0 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 319.0
WLSH3_k127_9771970_1 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000009014 220.0
WLSH3_k127_9771970_3 Protein of unknown function (DUF3995) - - - 0.000000000000002162 77.0
WLSH3_k127_9899839_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 477.0
WLSH3_k127_9899839_1 Chemoreceptor zinc-binding domain - - - 0.00000000000000000000000000000006436 130.0
WLSH3_k127_997591_0 COG3209 Rhs family protein - - - 0.00000000007993 73.0