Overview

ID MAG04264
Name WLSH3_bin.50
Sample SMP0111
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species
Assembly information
Completeness (%) 89.35
Contamination (%) 2.21
GC content (%) 38.0
N50 (bp) 16,793
Genome size (bp) 1,540,131

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1334

Gene name Description KEGG GOs EC E-value Score Sequence
WLSH3_k127_10059270_0 Aromatic amino acid lyase K01745 - 4.3.1.3 3.23e-262 815.0
WLSH3_k127_10059270_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 8.046e-222 700.0
WLSH3_k127_10059270_10 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000232 254.0
WLSH3_k127_10059270_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001298 252.0
WLSH3_k127_10059270_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000003638 234.0
WLSH3_k127_10059270_13 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000002134 218.0
WLSH3_k127_10059270_14 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000001806 147.0
WLSH3_k127_10059270_15 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000003804 105.0
WLSH3_k127_10059270_16 Belongs to the peptidase M28 family - - - 0.0000000000000000000000273 114.0
WLSH3_k127_10059270_17 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000007367 91.0
WLSH3_k127_10059270_18 snRNP Sm proteins K04796 - - 0.0000000000000000369 83.0
WLSH3_k127_10059270_19 Peptidase family C25 - - - 0.00000001317 67.0
WLSH3_k127_10059270_2 Radical SAM domain protein K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 468.0
WLSH3_k127_10059270_3 TIGRFAM Small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 397.0
WLSH3_k127_10059270_4 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 394.0
WLSH3_k127_10059270_5 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 365.0
WLSH3_k127_10059270_6 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 338.0
WLSH3_k127_10059270_7 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 325.0
WLSH3_k127_10059270_8 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 296.0
WLSH3_k127_10059270_9 glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
WLSH3_k127_10081244_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.0000000000000000000000000000000000000000000000000000007485 197.0
WLSH3_k127_10081244_1 Archaeal holliday junction resolvase (hjc) - - - 0.000000000000000000000000000000000000000000004552 169.0
WLSH3_k127_10081244_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000001058 156.0
WLSH3_k127_10081244_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000003413 153.0
WLSH3_k127_10081244_4 signal transduction protein with CBS domains - - - 0.000000000000000000000000000392 120.0
WLSH3_k127_10081244_5 - - - - 0.00000000000000000000003937 103.0
WLSH3_k127_10081244_6 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.00000000000000000005573 94.0
WLSH3_k127_10081244_7 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000000000000002152 101.0
WLSH3_k127_10162167_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1103.0
WLSH3_k127_10162167_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.648e-238 749.0
WLSH3_k127_10162167_10 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 316.0
WLSH3_k127_10162167_11 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 306.0
WLSH3_k127_10162167_12 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003704 284.0
WLSH3_k127_10162167_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004776 250.0
WLSH3_k127_10162167_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000002538 233.0
WLSH3_k127_10162167_15 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.00000000000000000000000000000000000000000000000000000000002196 209.0
WLSH3_k127_10162167_16 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000001132 209.0
WLSH3_k127_10162167_17 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000009244 203.0
WLSH3_k127_10162167_18 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000005582 196.0
WLSH3_k127_10162167_19 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000004662 166.0
WLSH3_k127_10162167_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.843e-225 705.0
WLSH3_k127_10162167_20 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000006505 149.0
WLSH3_k127_10162167_21 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000001949 150.0
WLSH3_k127_10162167_22 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000003196 106.0
WLSH3_k127_10162167_23 NADH dehydrogenase (Ubiquinone), 30 kDa subunit K00332,K14089 - 1.6.5.3 0.000000000000000000000001081 108.0
WLSH3_k127_10162167_24 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000004719 101.0
WLSH3_k127_10162167_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000003352 103.0
WLSH3_k127_10162167_26 Uncharacterised protein family (UPF0147) K09721 - - 0.000000000000000000000468 97.0
WLSH3_k127_10162167_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000003003 97.0
WLSH3_k127_10162167_28 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000003222 91.0
WLSH3_k127_10162167_29 PFAM peptidase M52 hydrogen uptake protein K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.000000000000000001306 92.0
WLSH3_k127_10162167_3 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 5.44e-207 659.0
WLSH3_k127_10162167_30 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000002181 77.0
WLSH3_k127_10162167_31 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000004391 72.0
WLSH3_k127_10162167_32 Domain of unknown function (DUF4382) - - - 0.0000000000009634 75.0
WLSH3_k127_10162167_33 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.000000000009747 68.0
WLSH3_k127_10162167_34 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K00340 - 1.6.5.3 0.00000001143 61.0
WLSH3_k127_10162167_35 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000002305 59.0
WLSH3_k127_10162167_37 CAAX protease self-immunity - - - 0.000003793 57.0
WLSH3_k127_10162167_38 - - - - 0.000006897 51.0
WLSH3_k127_10162167_39 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00002496 49.0
WLSH3_k127_10162167_4 DEAD DEAH box helicase domain protein K10896 - - 4.745e-204 659.0
WLSH3_k127_10162167_40 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0001129 53.0
WLSH3_k127_10162167_41 Uncharacterised protein - - - 0.0001455 52.0
WLSH3_k127_10162167_5 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 465.0
WLSH3_k127_10162167_6 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 447.0
WLSH3_k127_10162167_7 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 340.0
WLSH3_k127_10162167_8 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 323.0
WLSH3_k127_10162167_9 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 323.0
WLSH3_k127_10493846_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 604.0
WLSH3_k127_10493846_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 477.0
WLSH3_k127_10493846_2 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001299 259.0
WLSH3_k127_10493846_3 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000002268 233.0
WLSH3_k127_10493846_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000543 164.0
WLSH3_k127_1053264_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000001883 135.0
WLSH3_k127_1053264_1 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000001649 131.0
WLSH3_k127_1053264_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000005246 72.0
WLSH3_k127_10613969_0 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000001372 94.0
WLSH3_k127_10613969_1 MarR family transcriptional regulator - - - 0.0000000003584 64.0
WLSH3_k127_10613969_2 helix_turn_helix ASNC type K03719 - - 0.0000002216 63.0
WLSH3_k127_10613969_3 COG1522 Transcriptional regulators - - - 0.0000006183 58.0
WLSH3_k127_10613969_4 PFAM TPR repeat-containing protein - - - 0.00001258 58.0
WLSH3_k127_10613969_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001051 55.0
WLSH3_k127_10613969_6 helix_turn_helix ASNC type K03719 - - 0.0001942 53.0
WLSH3_k127_10737891_0 Peptidase S8 K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000137 189.0
WLSH3_k127_10737891_1 Zn_pept K05996 - 3.4.17.18 0.000000000000000000000000000000000000000000005906 175.0
WLSH3_k127_10737891_2 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00002395 58.0
WLSH3_k127_10785724_0 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005614 282.0
WLSH3_k127_10785724_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000003254 186.0
WLSH3_k127_10785724_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000001925 143.0
WLSH3_k127_11078776_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000002772 139.0
WLSH3_k127_11078776_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000002156 117.0
WLSH3_k127_11078776_2 - K00960 - 2.7.7.6 0.0000000000000000003157 87.0
WLSH3_k127_11078776_3 - - - - 0.00001655 49.0
WLSH3_k127_11128300_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 550.0
WLSH3_k127_11128300_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 445.0
WLSH3_k127_11128300_10 PFAM TPR repeat-containing protein - - - 0.0000007762 61.0
WLSH3_k127_11128300_11 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00005159 46.0
WLSH3_k127_11128300_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000007601 258.0
WLSH3_k127_11128300_3 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000008245 230.0
WLSH3_k127_11128300_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000003735 199.0
WLSH3_k127_11128300_5 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000005721 148.0
WLSH3_k127_11128300_6 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000002973 147.0
WLSH3_k127_11128300_7 protein conserved in archaea - - - 0.000000000000000001267 89.0
WLSH3_k127_11128300_8 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000008044 78.0
WLSH3_k127_11128300_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000007303 68.0
WLSH3_k127_11212806_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 359.0
WLSH3_k127_11212806_1 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 349.0
WLSH3_k127_11212806_10 membrane-associated protein domain - - - 0.0000000605 65.0
WLSH3_k127_11212806_11 Monocarboxylate transporter - - - 0.0006876 51.0
WLSH3_k127_11212806_2 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 325.0
WLSH3_k127_11212806_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 309.0
WLSH3_k127_11212806_4 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005407 286.0
WLSH3_k127_11212806_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000001265 206.0
WLSH3_k127_11212806_6 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000003122 169.0
WLSH3_k127_11212806_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003274 139.0
WLSH3_k127_11212806_8 PFAM Fibronectin type III domain - - - 0.000000000000000000000006536 110.0
WLSH3_k127_11212806_9 Peptidase C10 family - - - 0.00000000000000000000001296 116.0
WLSH3_k127_11216367_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000005962 208.0
WLSH3_k127_11216367_1 - - - - 0.000000000000000000000000000000000000000000000000000005656 199.0
WLSH3_k127_11216367_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000001449 178.0
WLSH3_k127_11216367_3 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000002511 183.0
WLSH3_k127_11216367_4 glucosylceramidase activity - - - 0.00000000000000000000000000003356 120.0
WLSH3_k127_11216367_5 PFAM Nitroreductase - - - 0.0000000000000008322 90.0
WLSH3_k127_11216367_6 PFAM Nitroreductase - - - 0.000000002721 69.0
WLSH3_k127_11266000_0 double-strand break repair K01867,K09946 - 6.1.1.2 0.0000000000000002073 81.0
WLSH3_k127_11266000_1 helix_turn_helix ASNC type K03719 - - 0.0000004035 58.0
WLSH3_k127_11266840_0 - - - - 0.00000000000000000000000000000000000000002104 158.0
WLSH3_k127_11266840_1 Peptidase family C25 - - - 0.00000000229 70.0
WLSH3_k127_11266840_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002109 54.0
WLSH3_k127_1132420_0 Peptidase family C25 - - - 0.00000006537 64.0
WLSH3_k127_11389471_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 595.0
WLSH3_k127_11389471_1 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000004342 87.0
WLSH3_k127_11424949_0 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 576.0
WLSH3_k127_11424949_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 484.0
WLSH3_k127_11424949_10 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000003712 153.0
WLSH3_k127_11424949_11 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000008813 155.0
WLSH3_k127_11424949_12 Uncharacterised protein family (UPF0179) K09730 - - 0.000000000000000000000000000000007901 132.0
WLSH3_k127_11424949_13 - - - - 0.000000000000000000000001541 108.0
WLSH3_k127_11424949_14 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000001491 93.0
WLSH3_k127_11424949_15 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000000227 85.0
WLSH3_k127_11424949_16 Transglutaminase-like superfamily - - - 0.00000000000219 78.0
WLSH3_k127_11424949_17 Methionine biosynthesis protein MetW - - - 0.00000000001915 73.0
WLSH3_k127_11424949_18 Thioredoxin - - - 0.0000000001131 66.0
WLSH3_k127_11424949_19 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.0000000004722 64.0
WLSH3_k127_11424949_2 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 452.0
WLSH3_k127_11424949_20 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000004115 70.0
WLSH3_k127_11424949_21 Bacterial transferase hexapeptide - - - 0.000000005511 66.0
WLSH3_k127_11424949_22 - - - - 0.000005312 50.0
WLSH3_k127_11424949_24 PFAM transglutaminase domain protein - - - 0.000009661 58.0
WLSH3_k127_11424949_25 Uncharacterized protein conserved in bacteria (DUF2090) K03338 - 2.7.1.92 0.00004016 55.0
WLSH3_k127_11424949_26 lysyltransferase activity K07027 - - 0.00004593 55.0
WLSH3_k127_11424949_3 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 412.0
WLSH3_k127_11424949_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 360.0
WLSH3_k127_11424949_5 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 351.0
WLSH3_k127_11424949_6 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007797 278.0
WLSH3_k127_11424949_7 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000003076 262.0
WLSH3_k127_11424949_8 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000798 240.0
WLSH3_k127_11424949_9 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000000000000004056 184.0
WLSH3_k127_11454671_0 Thrombospondin type 3 repeat - - - 0.00001521 52.0
WLSH3_k127_11474165_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 544.0
WLSH3_k127_11474165_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 395.0
WLSH3_k127_11474165_10 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 297.0
WLSH3_k127_11474165_11 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 294.0
WLSH3_k127_11474165_12 Pheromone shutdown protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 301.0
WLSH3_k127_11474165_13 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004145 276.0
WLSH3_k127_11474165_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001724 272.0
WLSH3_k127_11474165_15 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008475 262.0
WLSH3_k127_11474165_16 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001703 263.0
WLSH3_k127_11474165_17 Forms part of the polypeptide exit tunnel K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002046 258.0
WLSH3_k127_11474165_18 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000214 254.0
WLSH3_k127_11474165_19 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003247 257.0
WLSH3_k127_11474165_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 371.0
WLSH3_k127_11474165_20 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000004535 238.0
WLSH3_k127_11474165_21 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000005986 237.0
WLSH3_k127_11474165_22 BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000000000000000000004205 229.0
WLSH3_k127_11474165_23 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000000000003096 228.0
WLSH3_k127_11474165_24 PFAM LemA - - - 0.00000000000000000000000000000000000000000000000000000000000005432 218.0
WLSH3_k127_11474165_25 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
WLSH3_k127_11474165_26 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001322 203.0
WLSH3_k127_11474165_27 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000003722 187.0
WLSH3_k127_11474165_28 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000008947 183.0
WLSH3_k127_11474165_29 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000154 184.0
WLSH3_k127_11474165_3 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 346.0
WLSH3_k127_11474165_30 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000001173 176.0
WLSH3_k127_11474165_31 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000006572 181.0
WLSH3_k127_11474165_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000001166 171.0
WLSH3_k127_11474165_33 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000004948 168.0
WLSH3_k127_11474165_34 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000002547 163.0
WLSH3_k127_11474165_35 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000004732 159.0
WLSH3_k127_11474165_36 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000001646 149.0
WLSH3_k127_11474165_37 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000002211 154.0
WLSH3_k127_11474165_38 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000009242 143.0
WLSH3_k127_11474165_39 methyltransferase activity K00577 - 2.1.1.86 0.0000000000000000000000000000000000002891 147.0
WLSH3_k127_11474165_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 353.0
WLSH3_k127_11474165_40 - - - - 0.00000000000000000000000000000000002853 145.0
WLSH3_k127_11474165_41 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000006751 135.0
WLSH3_k127_11474165_42 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001477 138.0
WLSH3_k127_11474165_43 Lysine methyltransferase K02493 - 2.1.1.297 0.00000000000000000000000000000004209 133.0
WLSH3_k127_11474165_44 Peptidase family M50 - - - 0.000000000000000000000000003834 120.0
WLSH3_k127_11474165_45 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000047 116.0
WLSH3_k127_11474165_46 ribosomal protein L24 K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000004954 110.0
WLSH3_k127_11474165_47 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000000000007324 106.0
WLSH3_k127_11474165_48 OB-fold nucleic acid binding domain - - - 0.0000000000000000000002384 106.0
WLSH3_k127_11474165_49 PIN domain of ribonuclease K07060 - - 0.0000000000000000000009446 102.0
WLSH3_k127_11474165_5 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 340.0
WLSH3_k127_11474165_50 ribosomal protein S14 K02954 - - 0.000000000000000001918 85.0
WLSH3_k127_11474165_51 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000009446 85.0
WLSH3_k127_11474165_52 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000001926 80.0
WLSH3_k127_11474165_53 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000347 75.0
WLSH3_k127_11474165_54 COG2002 Regulators of stationary sporulation gene expression - - - 0.0000000003326 62.0
WLSH3_k127_11474165_55 Winged helix-turn-helix domain (DUF2582) - - - 0.000008665 53.0
WLSH3_k127_11474165_56 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00001376 51.0
WLSH3_k127_11474165_57 Winged helix-turn-helix domain (DUF2582) - - - 0.00005575 51.0
WLSH3_k127_11474165_58 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0001078 52.0
WLSH3_k127_11474165_59 Alternative locus ID - - - 0.0001746 48.0
WLSH3_k127_11474165_6 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 344.0
WLSH3_k127_11474165_7 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 324.0
WLSH3_k127_11474165_8 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 318.0
WLSH3_k127_11474165_9 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 309.0
WLSH3_k127_11500126_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 332.0
WLSH3_k127_11500126_1 PFAM membrane-flanked domain K09167 - - 0.0000000005936 68.0
WLSH3_k127_11500126_2 helix_turn_helix ASNC type K03719 - - 0.00000134 57.0
WLSH3_k127_11511932_1 Peptidase family C25 - - - 0.0000000000001653 84.0
WLSH3_k127_11511932_2 membrane-associated protein domain - - - 0.0000000001358 74.0
WLSH3_k127_11511932_3 helix_turn_helix ASNC type K03719 - - 0.0002432 50.0
WLSH3_k127_11554326_0 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.00000000000000000000000000000006508 130.0
WLSH3_k127_11554326_1 Peptidase C13 family - - - 0.00000000000000000000007367 115.0
WLSH3_k127_11554326_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000001167 99.0
WLSH3_k127_11554326_3 Vacuolar protein sorting-associated protein 62 - GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006605,GO:0006623,GO:0006810,GO:0006886,GO:0007034,GO:0008104,GO:0008150,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0031090,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072665,GO:0072666,GO:0098588,GO:0098805,GO:0098852 - 0.0000000000000004082 92.0
WLSH3_k127_11554326_4 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00000002479 57.0
WLSH3_k127_120328_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 329.0
WLSH3_k127_120328_1 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 281.0
WLSH3_k127_1269602_0 Papain family cysteine protease - - - 0.0000000000000000000000000000001799 139.0
WLSH3_k127_1269602_1 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000000000000000000001381 126.0
WLSH3_k127_1269602_2 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000007656 96.0
WLSH3_k127_1269602_3 lipolytic protein G-D-S-L family - - - 0.000000001916 66.0
WLSH3_k127_1290426_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000002307 213.0
WLSH3_k127_1290426_1 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000001205 128.0
WLSH3_k127_1290426_2 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.000001765 62.0
WLSH3_k127_1322891_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 598.0
WLSH3_k127_1322891_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 572.0
WLSH3_k127_1322891_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 385.0
WLSH3_k127_1322891_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000003236 238.0
WLSH3_k127_1322891_4 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000004352 199.0
WLSH3_k127_1322891_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000003343 146.0
WLSH3_k127_1322891_6 conserved protein, contains double-stranded beta-helix domain - - - 0.000000000000000000001319 98.0
WLSH3_k127_1322891_7 PFAM ABC transporter K02028 - 3.6.3.21 0.00000000000000000009917 90.0
WLSH3_k127_1322891_8 PFAM conserved K07027 - - 0.00000009559 63.0
WLSH3_k127_1326487_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000002495 196.0
WLSH3_k127_1326487_1 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000432 89.0
WLSH3_k127_1333615_0 parallel beta-helix repeat K03671 - - 0.000000000000006501 84.0
WLSH3_k127_1408887_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 8.677e-222 704.0
WLSH3_k127_1408887_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 400.0
WLSH3_k127_1408887_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000007492 183.0
WLSH3_k127_1408887_3 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000003942 166.0
WLSH3_k127_1408887_4 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.000000000726 69.0
WLSH3_k127_1408887_5 bacterial-type flagellum-dependent cell motility - - - 0.000000008952 68.0
WLSH3_k127_1408887_6 Nicotianamine synthase protein - - - 0.00000008695 61.0
WLSH3_k127_146692_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 509.0
WLSH3_k127_146692_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 500.0
WLSH3_k127_146692_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 496.0
WLSH3_k127_146692_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000001175 164.0
WLSH3_k127_146692_4 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000001133 149.0
WLSH3_k127_146692_5 PAS domain K09155 - - 0.0000000000000000000000000000004659 126.0
WLSH3_k127_146692_6 archaeal coiled-coil protein - - - 0.000000000000000000000000005365 122.0
WLSH3_k127_1485728_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 8.362e-239 745.0
WLSH3_k127_1485728_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 572.0
WLSH3_k127_1485728_10 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000004536 187.0
WLSH3_k127_1485728_11 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000003724 162.0
WLSH3_k127_1485728_12 TraB family - - - 0.0000000000000000000000000000000000565 143.0
WLSH3_k127_1485728_13 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000003505 139.0
WLSH3_k127_1485728_14 Peptidase family M28 - - - 0.000000000000000000000000004376 126.0
WLSH3_k127_1485728_15 Belongs to the universal stress protein A family - - - 0.000000000008134 70.0
WLSH3_k127_1485728_16 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.000000001397 69.0
WLSH3_k127_1485728_17 - - - - 0.000001553 52.0
WLSH3_k127_1485728_18 metallopeptidase activity - - - 0.000002453 53.0
WLSH3_k127_1485728_19 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000148 53.0
WLSH3_k127_1485728_2 Cysteinyl-tRNA synthetase K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 479.0
WLSH3_k127_1485728_20 ribosomal small subunit binding - - - 0.0001678 53.0
WLSH3_k127_1485728_3 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 464.0
WLSH3_k127_1485728_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 434.0
WLSH3_k127_1485728_5 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
WLSH3_k127_1485728_6 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000575 254.0
WLSH3_k127_1485728_7 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000007272 229.0
WLSH3_k127_1485728_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000002117 210.0
WLSH3_k127_1485728_9 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000001944 186.0
WLSH3_k127_1526391_0 K -dependent Na Ca exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000303 193.0
WLSH3_k127_1526391_1 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000001096 138.0
WLSH3_k127_1526391_2 Putative small multi-drug export protein - - - 0.000000000000000000000000000001094 128.0
WLSH3_k127_1526391_3 Putative Phosphatase K01079 - 3.1.3.3 0.00000000000000000000000002074 117.0
WLSH3_k127_1668918_0 Transcriptional regulator K07729 - - 0.000000007407 57.0
WLSH3_k127_1668918_1 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0006402 52.0
WLSH3_k127_1680086_0 PhoQ Sensor - - - 0.000000000000000000000000000000000002425 151.0
WLSH3_k127_1748014_0 PFAM type II secretion system K07333 - - 0.000000000000000000000007245 107.0
WLSH3_k127_1748014_1 PFAM PKD domain containing protein - - - 0.000000000000000002062 96.0
WLSH3_k127_1748014_2 metallopeptidase activity K01179 - 3.2.1.4 0.0000001691 64.0
WLSH3_k127_1872261_0 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
WLSH3_k127_1872261_1 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 291.0
WLSH3_k127_1872261_2 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000004876 197.0
WLSH3_k127_1872261_3 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000004108 104.0
WLSH3_k127_1872261_4 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000007043 57.0
WLSH3_k127_1872261_5 - - - - 0.0001721 50.0
WLSH3_k127_1872261_6 Transport permease protein K01992 - - 0.0006664 49.0
WLSH3_k127_1918465_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 372.0
WLSH3_k127_1918465_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 250.0
WLSH3_k127_1918465_2 Leucyl aminopeptidase K19701 - 3.4.11.10,3.4.11.6 0.00000000000000000001318 105.0
WLSH3_k127_1918465_3 Lrp/AsnC ligand binding domain - - - 0.000000001363 64.0
WLSH3_k127_1949993_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.498e-224 711.0
WLSH3_k127_1949993_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.144e-195 623.0
WLSH3_k127_1949993_10 GTP-binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 293.0
WLSH3_k127_1949993_11 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 298.0
WLSH3_k127_1949993_12 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004396 267.0
WLSH3_k127_1949993_13 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000000000000003706 262.0
WLSH3_k127_1949993_14 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000242 226.0
WLSH3_k127_1949993_15 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000001005 214.0
WLSH3_k127_1949993_16 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000001586 201.0
WLSH3_k127_1949993_17 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000001352 203.0
WLSH3_k127_1949993_18 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000002535 175.0
WLSH3_k127_1949993_19 PFAM PEGA domain - - - 0.0000000000000000000000000000000000003607 158.0
WLSH3_k127_1949993_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 602.0
WLSH3_k127_1949993_20 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000003394 138.0
WLSH3_k127_1949993_21 Membrane - - - 0.000000000000000000000000000001021 130.0
WLSH3_k127_1949993_22 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000008604 116.0
WLSH3_k127_1949993_23 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000001105 96.0
WLSH3_k127_1949993_24 Belongs to the UPF0235 family K09131 - - 0.000000000000000002002 89.0
WLSH3_k127_1949993_25 Zn-ribbon containing protein K07163 - - 0.000000000000000003363 91.0
WLSH3_k127_1949993_26 Cold shock protein domain K03704 - - 0.00000000000000001002 84.0
WLSH3_k127_1949993_27 Peptidase m28 - - - 0.0000000000000001559 93.0
WLSH3_k127_1949993_28 TOPRIM - - - 0.000000000000001032 83.0
WLSH3_k127_1949993_29 - - - - 0.0000000000005006 80.0
WLSH3_k127_1949993_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 468.0
WLSH3_k127_1949993_30 Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.00000006413 66.0
WLSH3_k127_1949993_31 Domain of unknown function (DUF4430) - - - 0.0000001141 63.0
WLSH3_k127_1949993_32 alpha-amylase - - - 0.0000005519 57.0
WLSH3_k127_1949993_33 - - - - 0.000003529 51.0
WLSH3_k127_1949993_34 PFAM PKD domain containing protein - - - 0.0007077 51.0
WLSH3_k127_1949993_4 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 475.0
WLSH3_k127_1949993_5 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 472.0
WLSH3_k127_1949993_6 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 428.0
WLSH3_k127_1949993_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 382.0
WLSH3_k127_1949993_8 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 368.0
WLSH3_k127_1949993_9 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 336.0
WLSH3_k127_2078375_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 312.0
WLSH3_k127_2078375_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000598 202.0
WLSH3_k127_2078375_2 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.0000000000000000000000000000000000000000000000000007627 199.0
WLSH3_k127_2078375_3 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.000000000000000000000000000000000000002862 151.0
WLSH3_k127_2078375_4 Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000004397 131.0
WLSH3_k127_2078375_5 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000007222 113.0
WLSH3_k127_2078375_6 PFAM FIST C domain - - - 0.0003471 53.0
WLSH3_k127_2198160_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 483.0
WLSH3_k127_2198160_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 373.0
WLSH3_k127_2198160_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 312.0
WLSH3_k127_2198160_3 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000001322 214.0
WLSH3_k127_2198160_4 Rhomboid family - - - 0.000000000000000000000003894 114.0
WLSH3_k127_2198160_5 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000003363 80.0
WLSH3_k127_2265473_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000002301 65.0
WLSH3_k127_2342796_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 310.0
WLSH3_k127_2342796_1 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
WLSH3_k127_2342796_10 cellulase activity - - - 0.000000001194 72.0
WLSH3_k127_2342796_11 Transcriptional - - - 0.00004571 52.0
WLSH3_k127_2342796_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000009507 245.0
WLSH3_k127_2342796_3 Psort location Cytoplasmic, score K06934 - - 0.00000000000000000000000000000000000000000002287 165.0
WLSH3_k127_2342796_4 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000006015 163.0
WLSH3_k127_2342796_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000001453 154.0
WLSH3_k127_2342796_6 coenzyme F390 K01912 - 6.2.1.30 0.0000000000000000000000000000009815 137.0
WLSH3_k127_2342796_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000006127 120.0
WLSH3_k127_2342796_8 PFAM Peptidase C1A, papain - - - 0.000000000000000000001043 111.0
WLSH3_k127_2342796_9 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain - - - 0.00000000000000000002278 92.0
WLSH3_k127_2384015_1 - - - - 0.0004055 49.0
WLSH3_k127_2575755_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 348.0
WLSH3_k127_2575755_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 309.0
WLSH3_k127_2575755_2 - K03741 - 1.20.4.1 0.000000000001378 72.0
WLSH3_k127_2622289_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004738 250.0
WLSH3_k127_2622289_1 Cupin domain - - - 0.00000000000000000000000000000000006663 136.0
WLSH3_k127_2814768_0 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 415.0
WLSH3_k127_2814768_1 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 314.0
WLSH3_k127_2814768_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 295.0
WLSH3_k127_2814768_3 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 293.0
WLSH3_k127_2814768_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002485 231.0
WLSH3_k127_2814768_5 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000004041 214.0
WLSH3_k127_2814768_6 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.000000000000000000000003463 108.0
WLSH3_k127_2814768_7 - - - - 0.0000000000000001787 80.0
WLSH3_k127_2814768_8 Uncharacterised protein family UPF0058 - - - 0.0000000004878 64.0
WLSH3_k127_2918038_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 554.0
WLSH3_k127_2918038_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 544.0
WLSH3_k127_2918038_10 ABC transporter, ATP-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002673 268.0
WLSH3_k127_2918038_11 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002722 255.0
WLSH3_k127_2918038_12 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000005796 258.0
WLSH3_k127_2918038_13 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000006594 230.0
WLSH3_k127_2918038_14 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000008473 226.0
WLSH3_k127_2918038_15 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
WLSH3_k127_2918038_16 methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000000000005598 214.0
WLSH3_k127_2918038_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000003086 199.0
WLSH3_k127_2918038_18 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000004026 194.0
WLSH3_k127_2918038_19 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000000000000001273 172.0
WLSH3_k127_2918038_2 P-type ATPase K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 539.0
WLSH3_k127_2918038_20 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000003117 147.0
WLSH3_k127_2918038_21 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000001248 117.0
WLSH3_k127_2918038_22 Transcriptional regulator, TrmB - - - 0.00000000000000000000000008463 111.0
WLSH3_k127_2918038_23 Predicted membrane protein (DUF2318) - - - 0.000000000000000000000003004 108.0
WLSH3_k127_2918038_24 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000427 74.0
WLSH3_k127_2918038_26 - - - - 0.00004901 49.0
WLSH3_k127_2918038_3 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 495.0
WLSH3_k127_2918038_4 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 492.0
WLSH3_k127_2918038_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 480.0
WLSH3_k127_2918038_6 resolution of meiotic recombination intermediates - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 474.0
WLSH3_k127_2918038_7 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 400.0
WLSH3_k127_2918038_8 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 349.0
WLSH3_k127_2918038_9 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 314.0
WLSH3_k127_2924443_0 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 429.0
WLSH3_k127_2924443_1 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003289 232.0
WLSH3_k127_2924443_2 membrane-associated protein domain - - - 0.00000001649 67.0
WLSH3_k127_2931194_0 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000001084 165.0
WLSH3_k127_3062982_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000003627 248.0
WLSH3_k127_3062982_1 Proline dehydrogenase transcriptional activator K03719 - - 0.00000001992 66.0
WLSH3_k127_3062982_2 COG1522 Transcriptional regulators K03719 - - 0.000007799 57.0
WLSH3_k127_3084531_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 2.593e-212 672.0
WLSH3_k127_3084531_1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 461.0
WLSH3_k127_3084531_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 293.0
WLSH3_k127_3084531_3 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004624 248.0
WLSH3_k127_3084531_4 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000002942 220.0
WLSH3_k127_3084531_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000001607 177.0
WLSH3_k127_3084531_6 HYR domain - - - 0.000000000000000000001936 100.0
WLSH3_k127_3084531_7 - - - - 0.00000000000000002792 87.0
WLSH3_k127_3139057_0 PFAM TPR repeat-containing protein - - - 0.0003654 53.0
WLSH3_k127_3266474_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.178e-201 638.0
WLSH3_k127_3266474_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 425.0
WLSH3_k127_3266474_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.00000000000000000000000000000000000000000000000000000000000000002029 232.0
WLSH3_k127_3266474_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00002597 51.0
WLSH3_k127_3367623_0 Belongs to the UPF0251 family - - - 0.00000000000000000000000000000003387 128.0
WLSH3_k127_3367623_1 nitrogen fixation - - - 0.0000000000000000000000009184 107.0
WLSH3_k127_3367623_2 protein conserved in archaea - - - 0.000000000001063 71.0
WLSH3_k127_3367623_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000002542 62.0
WLSH3_k127_3367623_4 PKD domain - - - 0.0000000294 63.0
WLSH3_k127_3452109_0 SPFH Band 7 PHB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 344.0
WLSH3_k127_3452109_1 Methyltransferase domain - - - 0.000000000000000000000188 108.0
WLSH3_k127_3452109_2 Radical SAM domain protein - - - 0.0000000001219 64.0
WLSH3_k127_3452109_3 Radical SAM domain protein - - - 0.00000009259 56.0
WLSH3_k127_3561985_0 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000005947 172.0
WLSH3_k127_3561985_1 Winged helix-turn-helix - - - 0.0000000000000000000000000005751 115.0
WLSH3_k127_3561985_2 - - - - 0.00000000000000003465 89.0
WLSH3_k127_3568911_0 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 610.0
WLSH3_k127_3568911_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 587.0
WLSH3_k127_3568911_10 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000005478 222.0
WLSH3_k127_3568911_11 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000002051 163.0
WLSH3_k127_3568911_12 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000004277 179.0
WLSH3_k127_3568911_13 NmrA-like family - - - 0.0000000000000000000000000000000000000001395 163.0
WLSH3_k127_3568911_14 metal ion transmembrane transporter activity - - - 0.00000000000000000000000000000000000008008 158.0
WLSH3_k127_3568911_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000002948 131.0
WLSH3_k127_3568911_16 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000006986 130.0
WLSH3_k127_3568911_17 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.0000000000000000000000000001192 124.0
WLSH3_k127_3568911_18 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000001351 127.0
WLSH3_k127_3568911_19 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000000000006425 109.0
WLSH3_k127_3568911_2 aminopeptidase K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 419.0
WLSH3_k127_3568911_20 Protein of unknown function (DUF998) - - - 0.000000000000000000000000123 111.0
WLSH3_k127_3568911_21 PFAM peptidase - - - 0.00000000000000000000008939 112.0
WLSH3_k127_3568911_22 Propeptide_C25 - - - 0.000000000000003639 89.0
WLSH3_k127_3568911_23 Propeptide_C25 - - - 0.0000000000001715 84.0
WLSH3_k127_3568911_24 Sugar (and other) transporter K08369 - - 0.000000000003245 79.0
WLSH3_k127_3568911_25 Sugar (and other) transporter K08369 - - 0.000000003282 69.0
WLSH3_k127_3568911_26 Transglutaminase-like superfamily - - - 0.00000004955 64.0
WLSH3_k127_3568911_27 Lrp/AsnC ligand binding domain - - - 0.0000001519 55.0
WLSH3_k127_3568911_28 PFAM response regulator receiver - - - 0.0000008686 56.0
WLSH3_k127_3568911_29 Domain of unknown function (DUF4082) - - - 0.000002304 60.0
WLSH3_k127_3568911_3 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 417.0
WLSH3_k127_3568911_30 Protein of unknown function (DUF998) - - - 0.00004269 48.0
WLSH3_k127_3568911_31 PFAM Transglutaminase-like - - - 0.0001173 53.0
WLSH3_k127_3568911_32 Esterase PHB depolymerase - - - 0.0002484 55.0
WLSH3_k127_3568911_33 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0008169 51.0
WLSH3_k127_3568911_4 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 412.0
WLSH3_k127_3568911_5 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 380.0
WLSH3_k127_3568911_6 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 363.0
WLSH3_k127_3568911_7 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 277.0
WLSH3_k127_3568911_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000002733 241.0
WLSH3_k127_3568911_9 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000004273 229.0
WLSH3_k127_3770205_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000005418 247.0
WLSH3_k127_3770205_1 CBS domain K03498 - - 0.0000000000000000000000000000000000000000000000003753 194.0
WLSH3_k127_3770205_2 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.000000000000000000000000001265 129.0
WLSH3_k127_3770205_3 COG0170 Dolichol kinase - - - 0.0002007 52.0
WLSH3_k127_3770572_0 Heat shock 70 kDa protein K04043 - - 5.655e-239 754.0
WLSH3_k127_3770572_1 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 9.426e-233 734.0
WLSH3_k127_3770572_10 Chlorophyllase enzyme - - - 0.00000000000001398 76.0
WLSH3_k127_3770572_2 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.8e-218 690.0
WLSH3_k127_3770572_3 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 501.0
WLSH3_k127_3770572_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 439.0
WLSH3_k127_3770572_5 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 408.0
WLSH3_k127_3770572_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000251 186.0
WLSH3_k127_3770572_7 Pfam:DUF552 K09152 - - 0.0000000000000000000000004361 108.0
WLSH3_k127_3770572_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000001557 97.0
WLSH3_k127_3770572_9 - - - - 0.00000000000000003919 88.0
WLSH3_k127_3905249_0 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 469.0
WLSH3_k127_3905249_1 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 451.0
WLSH3_k127_3905249_10 PFAM NAD dependent epimerase dehydratase family - - - 0.0000000000000000000000000000000000000000000001269 180.0
WLSH3_k127_3905249_11 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000388 153.0
WLSH3_k127_3905249_12 UbiA prenyltransferase family K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000000000000000000001422 157.0
WLSH3_k127_3905249_13 Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) - - - 0.000000000000001298 80.0
WLSH3_k127_3905249_14 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000001983 79.0
WLSH3_k127_3905249_15 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000002452 61.0
WLSH3_k127_3905249_16 Lipocalin-like domain - - - 0.000001581 60.0
WLSH3_k127_3905249_17 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0006909 51.0
WLSH3_k127_3905249_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 348.0
WLSH3_k127_3905249_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 294.0
WLSH3_k127_3905249_4 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001069 284.0
WLSH3_k127_3905249_5 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000001188 277.0
WLSH3_k127_3905249_6 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000593 259.0
WLSH3_k127_3905249_7 GHMP kinases C terminal K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000007288 254.0
WLSH3_k127_3905249_8 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000163 221.0
WLSH3_k127_3905249_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000002429 178.0
WLSH3_k127_3946240_0 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 443.0
WLSH3_k127_4008793_0 NHL repeat - - - 0.0000000000000000000000000000000000000006289 166.0
WLSH3_k127_4008793_1 PhoU domain - - - 0.000001606 50.0
WLSH3_k127_4008793_2 Sugar-specific transcriptional regulator TrmB - - - 0.00004194 54.0
WLSH3_k127_4038810_0 Protein of unknown function, DUF599 - - - 0.00001596 55.0
WLSH3_k127_4038810_1 Sulfite exporter TauE/SafE K07090 - - 0.0004082 44.0
WLSH3_k127_4085263_0 Peptidase family C25 - - - 0.00002062 57.0
WLSH3_k127_4144060_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1125.0
WLSH3_k127_4144060_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 7.064e-290 918.0
WLSH3_k127_4144060_10 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 383.0
WLSH3_k127_4144060_11 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 309.0
WLSH3_k127_4144060_12 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 292.0
WLSH3_k127_4144060_13 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002057 292.0
WLSH3_k127_4144060_14 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003056 274.0
WLSH3_k127_4144060_15 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001437 274.0
WLSH3_k127_4144060_16 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000001614 263.0
WLSH3_k127_4144060_17 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000005778 246.0
WLSH3_k127_4144060_18 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000008564 231.0
WLSH3_k127_4144060_19 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000002113 222.0
WLSH3_k127_4144060_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.848e-278 867.0
WLSH3_k127_4144060_20 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000004788 208.0
WLSH3_k127_4144060_21 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000004083 206.0
WLSH3_k127_4144060_22 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000003464 195.0
WLSH3_k127_4144060_23 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000000005741 190.0
WLSH3_k127_4144060_24 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000003195 188.0
WLSH3_k127_4144060_25 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000001071 175.0
WLSH3_k127_4144060_26 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000003407 165.0
WLSH3_k127_4144060_27 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.0000000000000000000000000000000000003716 143.0
WLSH3_k127_4144060_28 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000001551 133.0
WLSH3_k127_4144060_29 Putative small multi-drug export protein - - - 0.0000000000000000000000000000001482 129.0
WLSH3_k127_4144060_3 Cell division protein 48 (CDC48) domain 2 K13525 - - 1.115e-275 872.0
WLSH3_k127_4144060_30 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000002858 121.0
WLSH3_k127_4144060_31 PRC-barrel domain - - - 0.00000000000002433 76.0
WLSH3_k127_4144060_32 Transposase IS4 family protein K07495 - - 0.0000000000002633 73.0
WLSH3_k127_4144060_33 - K00390 - 1.8.4.10,1.8.4.8 0.0000000003617 63.0
WLSH3_k127_4144060_34 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000002113 62.0
WLSH3_k127_4144060_35 - - - - 0.000001425 57.0
WLSH3_k127_4144060_36 Bacterial PH domain - - - 0.00001073 57.0
WLSH3_k127_4144060_37 - - - - 0.00001303 55.0
WLSH3_k127_4144060_38 Transposase - - - 0.0003146 50.0
WLSH3_k127_4144060_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 585.0
WLSH3_k127_4144060_5 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 494.0
WLSH3_k127_4144060_6 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 456.0
WLSH3_k127_4144060_7 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
WLSH3_k127_4144060_8 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 405.0
WLSH3_k127_4144060_9 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 362.0
WLSH3_k127_4198620_0 COG0058 Glucan phosphorylase - - - 4.209e-221 699.0
WLSH3_k127_4198620_1 Glycogen debranching enzyme N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 476.0
WLSH3_k127_4198620_2 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 458.0
WLSH3_k127_4198620_3 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 425.0
WLSH3_k127_4198620_4 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 317.0
WLSH3_k127_4198620_5 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 312.0
WLSH3_k127_4198620_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004155 282.0
WLSH3_k127_4198620_7 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000002014 177.0
WLSH3_k127_4375583_0 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 455.0
WLSH3_k127_449177_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 2.756e-226 707.0
WLSH3_k127_449177_1 glutamate dehydrogenase [NAD(P)+] activity K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 2.337e-200 632.0
WLSH3_k127_449177_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 413.0
WLSH3_k127_449177_3 Asparaginase, N-terminal K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000008114 234.0
WLSH3_k127_449177_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000004309 119.0
WLSH3_k127_449177_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000002825 59.0
WLSH3_k127_4543765_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1090.0
WLSH3_k127_4543765_1 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 467.0
WLSH3_k127_4543765_10 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000006811 188.0
WLSH3_k127_4543765_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000005343 176.0
WLSH3_k127_4543765_12 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000002023 145.0
WLSH3_k127_4543765_13 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000002471 124.0
WLSH3_k127_4543765_14 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000006341 110.0
WLSH3_k127_4543765_15 FlgD Ig-like domain - - - 0.0000000000000002155 93.0
WLSH3_k127_4543765_16 Methyltransferase - - - 0.00000000000008355 81.0
WLSH3_k127_4543765_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000003592 52.0
WLSH3_k127_4543765_18 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000007295 55.0
WLSH3_k127_4543765_19 HNH endonuclease - - - 0.0001859 46.0
WLSH3_k127_4543765_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 441.0
WLSH3_k127_4543765_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 344.0
WLSH3_k127_4543765_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 319.0
WLSH3_k127_4543765_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006362 276.0
WLSH3_k127_4543765_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000495 237.0
WLSH3_k127_4543765_7 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000001474 232.0
WLSH3_k127_4543765_8 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000122 221.0
WLSH3_k127_4543765_9 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000001292 218.0
WLSH3_k127_4595921_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 1.829e-208 662.0
WLSH3_k127_4595921_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 402.0
WLSH3_k127_4595921_2 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002608 235.0
WLSH3_k127_4595921_3 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000002011 89.0
WLSH3_k127_4595921_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000005558 97.0
WLSH3_k127_4595921_5 Calcineurin-like phosphoesterase - - - 0.000000000005178 67.0
WLSH3_k127_4595921_6 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000001354 68.0
WLSH3_k127_4595921_7 - - - - 0.00000001132 58.0
WLSH3_k127_4595921_8 - - - - 0.0004171 51.0
WLSH3_k127_4621161_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 306.0
WLSH3_k127_4621161_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 312.0
WLSH3_k127_4621161_2 ABC-type dipeptide transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001829 267.0
WLSH3_k127_4621161_3 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 267.0
WLSH3_k127_4621161_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000003428 236.0
WLSH3_k127_4621161_5 Glycogen recognition site of AMP-activated protein kinase K01442 - 3.5.1.24 0.000000000000000000000000000000000009691 150.0
WLSH3_k127_4621161_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000001529 102.0
WLSH3_k127_4621161_7 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.0000000001142 68.0
WLSH3_k127_4621161_8 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.000000000218 70.0
WLSH3_k127_4621161_9 - - - - 0.0000001059 57.0
WLSH3_k127_4624907_0 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000001476 176.0
WLSH3_k127_4624907_1 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.0000000000000000000000000000000000003521 155.0
WLSH3_k127_4624907_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000008114 141.0
WLSH3_k127_4624907_3 secreted hydrolase - - - 0.00000000000000000004959 102.0
WLSH3_k127_4624907_4 FR47-like protein - - - 0.000000000000000001448 92.0
WLSH3_k127_4624907_5 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.000004124 58.0
WLSH3_k127_4681875_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001525 297.0
WLSH3_k127_4681875_1 Protein of unknown function (DUF554) K07150 - - 0.00000000005507 66.0
WLSH3_k127_4681875_2 membrane-associated protein domain - - - 0.0000004574 60.0
WLSH3_k127_47017_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001213 290.0
WLSH3_k127_47017_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005543 284.0
WLSH3_k127_47017_10 Propeptide_C25 - - - 0.00000000009718 74.0
WLSH3_k127_47017_11 Peptidase family C25 - - - 0.0000000005761 72.0
WLSH3_k127_47017_12 MafB19-like deaminase K01485 - 3.5.4.1 0.0000002889 53.0
WLSH3_k127_47017_13 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0002579 52.0
WLSH3_k127_47017_14 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000945 43.0
WLSH3_k127_47017_2 Abc transporter K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005742 283.0
WLSH3_k127_47017_3 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000888 227.0
WLSH3_k127_47017_4 - - - - 0.000000000000000000000000000000000000000000000000000000001269 203.0
WLSH3_k127_47017_5 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000002377 127.0
WLSH3_k127_47017_6 cheY-homologous receiver domain K07668 - - 0.0000000000000000000005124 101.0
WLSH3_k127_47017_7 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000000000000001279 93.0
WLSH3_k127_47017_8 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000003007 83.0
WLSH3_k127_47017_9 membrane-associated protein domain - - - 0.00000000005518 75.0
WLSH3_k127_4702275_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 350.0
WLSH3_k127_4702275_1 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 340.0
WLSH3_k127_4702275_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000002779 77.0
WLSH3_k127_4928109_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 367.0
WLSH3_k127_4928109_1 Cupin 2, conserved barrel domain protein K09988 - 5.3.1.15 0.000000000000000000000000000000000000000000000000000006801 191.0
WLSH3_k127_4928109_2 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000004204 175.0
WLSH3_k127_4928109_3 Zn_pept - - - 0.00000000004947 66.0
WLSH3_k127_4928109_4 Peptidase family C25 - - - 0.0000007046 63.0
WLSH3_k127_4945492_0 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 380.0
WLSH3_k127_4945492_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000004296 232.0
WLSH3_k127_4945492_2 Flavodoxin - - - 0.00000000000000000000000000000000000000000000001654 175.0
WLSH3_k127_4945492_3 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000001787 117.0
WLSH3_k127_4945492_4 Domain of unknown function (DUF1805) - - - 0.0000000000000000000003445 99.0
WLSH3_k127_4945492_5 Papain family cysteine protease - - - 0.0000000002365 64.0
WLSH3_k127_4945492_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000103 64.0
WLSH3_k127_5006152_0 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000002872 209.0
WLSH3_k127_5035294_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 500.0
WLSH3_k127_5035294_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 473.0
WLSH3_k127_5035294_10 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000006358 220.0
WLSH3_k127_5035294_11 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000001343 212.0
WLSH3_k127_5035294_12 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000143 214.0
WLSH3_k127_5035294_13 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000007773 208.0
WLSH3_k127_5035294_14 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000003183 210.0
WLSH3_k127_5035294_15 - K07092 - - 0.0000000000000000000000000000000000000000000000000000004093 194.0
WLSH3_k127_5035294_16 Desulfoferrodoxin ferrous iron-binding domain K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000024 192.0
WLSH3_k127_5035294_17 Small conductance mechanosensitive ion channel, MscS family K03442,K16052,K22044 - - 0.00000000000000000000000000000000000000000000000000006723 200.0
WLSH3_k127_5035294_18 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000007011 179.0
WLSH3_k127_5035294_19 Platelet-activating factor acetylhydrolase, isoform II - - - 0.00000000000000000000000000000000000000000003905 179.0
WLSH3_k127_5035294_2 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 435.0
WLSH3_k127_5035294_20 Rubrerythrin - - - 0.0000000000000000000000000000000000003209 146.0
WLSH3_k127_5035294_21 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000004059 133.0
WLSH3_k127_5035294_22 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000001042 125.0
WLSH3_k127_5035294_23 AraC-like ligand binding domain - - - 0.0000000000000000000000000000001841 127.0
WLSH3_k127_5035294_24 NUDIX domain - - - 0.000000000000000000000000000001275 125.0
WLSH3_k127_5035294_25 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000005902 124.0
WLSH3_k127_5035294_26 - - - - 0.000000000000000000000001423 108.0
WLSH3_k127_5035294_27 protein conserved in archaea - - - 0.00000000000000000007688 93.0
WLSH3_k127_5035294_29 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000237 78.0
WLSH3_k127_5035294_3 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 397.0
WLSH3_k127_5035294_30 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000001214 72.0
WLSH3_k127_5035294_31 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000001421 61.0
WLSH3_k127_5035294_32 Transposase IS200 like K07491 - - 0.000009944 49.0
WLSH3_k127_5035294_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 346.0
WLSH3_k127_5035294_5 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 351.0
WLSH3_k127_5035294_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 333.0
WLSH3_k127_5035294_7 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 306.0
WLSH3_k127_5035294_8 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006884 280.0
WLSH3_k127_5035294_9 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000503 254.0
WLSH3_k127_5117754_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.436e-248 786.0
WLSH3_k127_5117754_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.441e-205 649.0
WLSH3_k127_5117754_10 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.000000000000000000000000000000000000000000000003333 179.0
WLSH3_k127_5117754_11 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000005825 128.0
WLSH3_k127_5117754_12 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000002946 84.0
WLSH3_k127_5117754_13 DNA replication initiation K02541 GO:0000082,GO:0000228,GO:0000278,GO:0000428,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005657,GO:0005658,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005856,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0007049,GO:0007275,GO:0007399,GO:0007405,GO:0007417,GO:0007420,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009059,GO:0009987,GO:0015630,GO:0016319,GO:0022008,GO:0022402,GO:0030154,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0042555,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045120,GO:0046483,GO:0048471,GO:0048513,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0055029,GO:0060322,GO:0061351,GO:0061695,GO:0070013,GO:0071704,GO:0072089,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1902494,GO:1903047,GO:1990234 3.6.4.12 0.0000000005432 72.0
WLSH3_k127_5117754_14 response regulator, receiver - - - 0.00000819 53.0
WLSH3_k127_5117754_2 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 466.0
WLSH3_k127_5117754_3 PFAM Acyl-CoA dehydrogenase K00248,K22430 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108,1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 436.0
WLSH3_k127_5117754_4 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 370.0
WLSH3_k127_5117754_5 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001932 299.0
WLSH3_k127_5117754_6 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000008019 275.0
WLSH3_k127_5117754_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000002348 235.0
WLSH3_k127_5117754_8 RIO1 family K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000004319 205.0
WLSH3_k127_5117754_9 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000001572 184.0
WLSH3_k127_5202748_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
WLSH3_k127_5202748_1 Belongs to the CinA family K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000003209 166.0
WLSH3_k127_5202748_2 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000463 139.0
WLSH3_k127_5202748_3 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000005067 120.0
WLSH3_k127_532159_0 Protein of unknown function, DUF255 K06888 - - 8.291e-234 743.0
WLSH3_k127_532159_1 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000007232 194.0
WLSH3_k127_532159_2 PFAM AhpC TSA family K03564 - 1.11.1.15 0.00000000000000000004218 91.0
WLSH3_k127_532159_3 Leucine-rich repeat (LRR) protein - - - 0.0001643 45.0
WLSH3_k127_5435744_0 Belongs to the peptidase M28 family - - - 0.000000000000000000008041 106.0
WLSH3_k127_5435744_1 - - - - 0.000000000000005181 85.0
WLSH3_k127_5435744_2 Belongs to the ParA family K04562 - - 0.0000003116 53.0
WLSH3_k127_5435744_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0001025 46.0
WLSH3_k127_5435744_4 Transposase IS200 like K07491 - - 0.0008836 48.0
WLSH3_k127_5455687_0 KH, type 1, domain K07041 - - 1.147e-260 816.0
WLSH3_k127_5455687_1 helicase superfamily c-terminal domain K03724 - - 8.773e-250 802.0
WLSH3_k127_5455687_10 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 321.0
WLSH3_k127_5455687_11 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001339 282.0
WLSH3_k127_5455687_12 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009377 274.0
WLSH3_k127_5455687_13 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
WLSH3_k127_5455687_14 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007294 249.0
WLSH3_k127_5455687_15 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000001216 244.0
WLSH3_k127_5455687_16 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000003462 203.0
WLSH3_k127_5455687_17 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000003966 199.0
WLSH3_k127_5455687_18 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000313 196.0
WLSH3_k127_5455687_19 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000006072 192.0
WLSH3_k127_5455687_2 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 571.0
WLSH3_k127_5455687_20 cyclohydrolase K01746 - 4.3.1.4 0.000000000000000000000000000000000000000000000000001324 189.0
WLSH3_k127_5455687_21 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000005464 159.0
WLSH3_k127_5455687_22 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000007826 152.0
WLSH3_k127_5455687_23 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000008911 145.0
WLSH3_k127_5455687_24 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000002078 106.0
WLSH3_k127_5455687_25 Helix-turn-helix domain K03627 - - 0.000000000000000002432 91.0
WLSH3_k127_5455687_26 PRC-barrel domain - - - 0.00000000000003115 76.0
WLSH3_k127_5455687_27 - - - - 0.0000000002409 65.0
WLSH3_k127_5455687_28 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000001232 54.0
WLSH3_k127_5455687_29 - - - - 0.000006353 50.0
WLSH3_k127_5455687_3 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 479.0
WLSH3_k127_5455687_30 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0003338 46.0
WLSH3_k127_5455687_31 zinc-ribbon domain - - - 0.0004501 51.0
WLSH3_k127_5455687_4 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 449.0
WLSH3_k127_5455687_5 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 440.0
WLSH3_k127_5455687_6 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 434.0
WLSH3_k127_5455687_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 421.0
WLSH3_k127_5455687_8 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 363.0
WLSH3_k127_5455687_9 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 330.0
WLSH3_k127_54667_0 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000001131 196.0
WLSH3_k127_54667_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000003714 145.0
WLSH3_k127_54667_2 PFAM Radical SAM domain protein - - - 0.000000000000000004303 92.0
WLSH3_k127_54667_3 PFAM Radical SAM domain protein - - - 0.00002367 46.0
WLSH3_k127_5531113_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 330.0
WLSH3_k127_5531113_1 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.000000000000000000000000000000000000000000000000000000000000002652 222.0
WLSH3_k127_5531113_2 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.0000000000000000000000000000000000000003408 152.0
WLSH3_k127_5531113_3 Zn_pept K05996 - 3.4.17.18 0.00000000000000000000000000000000000189 153.0
WLSH3_k127_5531113_4 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000004425 134.0
WLSH3_k127_5531113_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000001003 118.0
WLSH3_k127_5531113_6 Family of unknown function (DUF5320) - - - 0.000000000000000000005306 96.0
WLSH3_k127_5531113_7 nitrogen fixation - - - 0.0000000000000000009603 87.0
WLSH3_k127_5531113_8 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000004885 65.0
WLSH3_k127_5531113_9 - - - - 0.0000000001848 72.0
WLSH3_k127_5686811_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 1.148e-261 816.0
WLSH3_k127_5686811_1 Threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 409.0
WLSH3_k127_5686811_2 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.0000000000000000000000002089 122.0
WLSH3_k127_5686811_3 Domain of unknown function (DUF4870) - - - 0.00000000000000000000004937 101.0
WLSH3_k127_5686811_4 - - - - 0.00000000000000002437 82.0
WLSH3_k127_5686811_5 PFAM PKD domain containing protein - - - 0.00000000000008506 85.0
WLSH3_k127_5686811_6 EamA-like transporter family - - - 0.00001619 56.0
WLSH3_k127_5695586_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.185e-256 806.0
WLSH3_k127_5695586_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.6e-198 626.0
WLSH3_k127_5695586_10 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000003094 216.0
WLSH3_k127_5695586_11 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000003185 205.0
WLSH3_k127_5695586_12 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000001848 192.0
WLSH3_k127_5695586_13 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.000000000000000000000000000000000000000000000000004714 186.0
WLSH3_k127_5695586_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000002261 170.0
WLSH3_k127_5695586_15 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000003884 164.0
WLSH3_k127_5695586_16 regulator of amino acid metabolism K07103 - - 0.000000000000000000000000000000000001314 144.0
WLSH3_k127_5695586_17 Phosphoesterase PA-phosphatase - - - 0.00000000000000003223 91.0
WLSH3_k127_5695586_18 FAD dependent oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000003943 91.0
WLSH3_k127_5695586_19 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.000000000122 73.0
WLSH3_k127_5695586_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 551.0
WLSH3_k127_5695586_20 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000008575 63.0
WLSH3_k127_5695586_21 Chlorophyll synthase, ChlG K04040 - 2.5.1.133,2.5.1.62 0.0000009809 60.0
WLSH3_k127_5695586_3 RmlD substrate binding domain K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 503.0
WLSH3_k127_5695586_4 PFAM GTPase of K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 448.0
WLSH3_k127_5695586_5 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 431.0
WLSH3_k127_5695586_6 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 351.0
WLSH3_k127_5695586_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 317.0
WLSH3_k127_5695586_8 Patched family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000206 293.0
WLSH3_k127_5695586_9 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004985 252.0
WLSH3_k127_5726834_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 417.0
WLSH3_k127_5726834_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 387.0
WLSH3_k127_5726834_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 369.0
WLSH3_k127_5726834_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 329.0
WLSH3_k127_5726834_4 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000005194 148.0
WLSH3_k127_5726834_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000006687 147.0
WLSH3_k127_5726834_6 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000007024 91.0
WLSH3_k127_5726834_7 Binds to the 23S rRNA K02922 - - 0.0000000000002413 72.0
WLSH3_k127_5726834_8 esterase K07000 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000001406 57.0
WLSH3_k127_5775080_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.627e-312 980.0
WLSH3_k127_5775080_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.698e-266 850.0
WLSH3_k127_5775080_2 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 1.595e-255 796.0
WLSH3_k127_5775080_3 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 526.0
WLSH3_k127_5775080_4 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000002919 241.0
WLSH3_k127_5775080_5 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000001499 216.0
WLSH3_k127_5775080_6 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000002161 203.0
WLSH3_k127_5775080_7 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000003215 188.0
WLSH3_k127_5775080_8 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 0.00000000000002835 79.0
WLSH3_k127_5834563_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002592 271.0
WLSH3_k127_5834563_1 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000006728 157.0
WLSH3_k127_5834563_2 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000001618 163.0
WLSH3_k127_5834563_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000003846 153.0
WLSH3_k127_5834563_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001428 145.0
WLSH3_k127_5834563_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000001415 91.0
WLSH3_k127_5834563_6 Transcriptional regulator - - - 0.000000000000000006244 93.0
WLSH3_k127_5834563_7 B-1 B cell differentiation - - - 0.000000000000000008765 94.0
WLSH3_k127_5834563_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000001185 68.0
WLSH3_k127_5834563_9 HYR domain - - - 0.000000254 63.0
WLSH3_k127_5878419_0 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001933 308.0
WLSH3_k127_5878419_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000001652 258.0
WLSH3_k127_5878419_2 deoxyribonucleoside 5'-monophosphate N-glycosidase activity K09457 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 1.7.1.13 0.0000144 53.0
WLSH3_k127_5878419_3 2TM domain - - - 0.00005384 48.0
WLSH3_k127_6017693_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1171.0
WLSH3_k127_6017693_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1157.0
WLSH3_k127_6017693_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000186 213.0
WLSH3_k127_6017693_11 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000001574 140.0
WLSH3_k127_6017693_12 Participates in transcription termination K02600 - - 0.00000000000000000000000000002257 122.0
WLSH3_k127_6017693_13 binds to the 23S rRNA K02921 - - 0.00000000000000000000000008787 109.0
WLSH3_k127_6017693_14 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000006686 103.0
WLSH3_k127_6017693_15 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000002 100.0
WLSH3_k127_6017693_16 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000004408 87.0
WLSH3_k127_6017693_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000009192 57.0
WLSH3_k127_6017693_2 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 469.0
WLSH3_k127_6017693_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 403.0
WLSH3_k127_6017693_4 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 313.0
WLSH3_k127_6017693_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 300.0
WLSH3_k127_6017693_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
WLSH3_k127_6017693_7 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000002044 250.0
WLSH3_k127_6017693_8 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000001126 236.0
WLSH3_k127_6017693_9 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000007445 226.0
WLSH3_k127_6137535_0 ABC transporter K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
WLSH3_k127_6137535_1 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.000000000000000000000000000000000000000000000000000000004645 207.0
WLSH3_k127_6137535_2 amino acid ABC transporter K02029 - - 0.00000000000000000000000000000000000000000000000000000000471 206.0
WLSH3_k127_6137535_3 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.000000000000000000000000000000000000000000000000000000008539 208.0
WLSH3_k127_6137535_4 Predicted SAM-dependent RNA methyltransferase - - - 0.00000000000000000000000000000000392 136.0
WLSH3_k127_6137535_5 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.00000000000000004837 83.0
WLSH3_k127_6137535_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000001953 83.0
WLSH3_k127_6137535_7 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000004933 49.0
WLSH3_k127_6373215_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.115e-222 710.0
WLSH3_k127_6373215_1 Asparaginase K01424 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 1.773e-215 677.0
WLSH3_k127_6373215_2 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 5.845e-196 622.0
WLSH3_k127_6373215_3 GatB/GatE catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 507.0
WLSH3_k127_6373215_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 356.0
WLSH3_k127_6373215_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000001207 206.0
WLSH3_k127_6373215_6 spore germination K03605 - - 0.00000000000000000000000036 110.0
WLSH3_k127_6373215_7 PFAM peptidylprolyl isomerase FKBP-type K01802 - 5.2.1.8 0.00000000000000000000006199 104.0
WLSH3_k127_6400232_0 Amino acid permease - - - 1.547e-268 841.0
WLSH3_k127_6400232_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 598.0
WLSH3_k127_6400232_10 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000006771 169.0
WLSH3_k127_6400232_11 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000002682 155.0
WLSH3_k127_6400232_12 - - - - 0.00000000000000000002889 93.0
WLSH3_k127_6400232_13 Protein of unknown function (DUF504) K09715 - - 0.000000005031 60.0
WLSH3_k127_6400232_14 C-terminal domain of CHU protein family - - - 0.0000002556 63.0
WLSH3_k127_6400232_15 bacterial-type flagellum-dependent cell motility - - - 0.00008502 54.0
WLSH3_k127_6400232_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 603.0
WLSH3_k127_6400232_3 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 505.0
WLSH3_k127_6400232_4 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 480.0
WLSH3_k127_6400232_5 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 436.0
WLSH3_k127_6400232_6 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 412.0
WLSH3_k127_6400232_7 Phosphopantothenate/pantothenate synthetase K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001054 284.0
WLSH3_k127_6400232_8 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000001528 224.0
WLSH3_k127_6400232_9 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000046 187.0
WLSH3_k127_6468101_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 310.0
WLSH3_k127_6468101_1 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001159 282.0
WLSH3_k127_6468101_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000000000000000003553 183.0
WLSH3_k127_6468101_3 cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000005377 163.0
WLSH3_k127_6468101_4 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000001519 59.0
WLSH3_k127_6491652_0 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.0000000000000000000000001737 123.0
WLSH3_k127_6491652_1 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000001106 102.0
WLSH3_k127_6491652_2 aminopeptidase activity - - - 0.00000000000000005448 92.0
WLSH3_k127_6491652_3 metallopeptidase activity - - - 0.0000000000003746 83.0
WLSH3_k127_6493740_0 protein conserved in archaea - - - 0.000000000000000000000000000001516 126.0
WLSH3_k127_6493740_1 META domain - - - 0.000351 53.0
WLSH3_k127_657896_0 Iron-containing alcohol dehydrogenase K19955 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 458.0
WLSH3_k127_657896_1 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000001109 173.0
WLSH3_k127_657896_2 Major facilitator superfamily - - - 0.00000000000000002503 94.0
WLSH3_k127_657896_3 parallel beta-helix repeat - - - 0.000000000000008579 85.0
WLSH3_k127_6713836_0 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000003255 147.0
WLSH3_k127_6713836_1 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000005305 121.0
WLSH3_k127_6713836_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.000000000001409 69.0
WLSH3_k127_6713836_3 Calcineurin-like phosphoesterase K01120,K03651 - 3.1.4.17,3.1.4.53 0.00000009232 64.0
WLSH3_k127_6721474_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 589.0
WLSH3_k127_6721474_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 368.0
WLSH3_k127_6721474_2 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000431 209.0
WLSH3_k127_6721474_3 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000002471 194.0
WLSH3_k127_6721474_4 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000000000000198 180.0
WLSH3_k127_6721474_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000004513 161.0
WLSH3_k127_6721474_6 binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006187 103.0
WLSH3_k127_6721474_7 Integral membrane protein DUF106 - - - 0.0000000000000000000002521 105.0
WLSH3_k127_6721474_8 - - - - 0.0004742 44.0
WLSH3_k127_6747969_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 8.95e-313 972.0
WLSH3_k127_6747969_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 6.244e-282 893.0
WLSH3_k127_6747969_10 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000009729 220.0
WLSH3_k127_6747969_11 HTH-type transcriptional regulatory protein K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000385 225.0
WLSH3_k127_6747969_12 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000006292 181.0
WLSH3_k127_6747969_13 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000006677 115.0
WLSH3_k127_6747969_14 - - - - 0.000000000000000000008631 93.0
WLSH3_k127_6747969_15 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000006474 81.0
WLSH3_k127_6747969_16 bacterial-type flagellum-dependent cell motility - - - 0.000000000003778 79.0
WLSH3_k127_6747969_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.466e-205 657.0
WLSH3_k127_6747969_3 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 4.176e-201 647.0
WLSH3_k127_6747969_4 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 548.0
WLSH3_k127_6747969_5 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 384.0
WLSH3_k127_6747969_6 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004152 269.0
WLSH3_k127_6747969_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006383 264.0
WLSH3_k127_6747969_8 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000004377 237.0
WLSH3_k127_6747969_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004986 228.0
WLSH3_k127_6782881_0 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 312.0
WLSH3_k127_6782881_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000694 187.0
WLSH3_k127_6782881_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000001052 180.0
WLSH3_k127_6782881_3 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001663 170.0
WLSH3_k127_6782881_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000001967 162.0
WLSH3_k127_6880808_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 608.0
WLSH3_k127_6880808_1 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 445.0
WLSH3_k127_6880808_10 Protein of unknown function (DUF996) - - - 0.00000000000002518 75.0
WLSH3_k127_6880808_11 - - - - 0.0000000002899 61.0
WLSH3_k127_6880808_12 transcriptional - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00008761 51.0
WLSH3_k127_6880808_13 Domain of unknown function (DU1801) - - - 0.0001238 49.0
WLSH3_k127_6880808_2 COG1131 ABC-type multidrug transport system ATPase component K16907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 358.0
WLSH3_k127_6880808_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001406 263.0
WLSH3_k127_6880808_4 HhH-GPD family K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000007213 241.0
WLSH3_k127_6880808_5 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000267 222.0
WLSH3_k127_6880808_6 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000004068 166.0
WLSH3_k127_6880808_7 ATPase, P-type transporting, HAD superfamily, subfamily IC K01531,K16905 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043492,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0099131,GO:0099132 3.6.3.2 0.00000000000000000000000007777 116.0
WLSH3_k127_6880808_8 transmembrane transport K01992 - - 0.000000000000000000000001223 112.0
WLSH3_k127_6880808_9 - - - - 0.00000000000000000000001055 104.0
WLSH3_k127_6899521_0 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000008672 129.0
WLSH3_k127_6899521_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000006731 79.0
WLSH3_k127_6899521_2 Starch synthase catalytic domain K13668 - 2.4.1.346 0.0000008322 52.0
WLSH3_k127_6951355_0 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000001458 168.0
WLSH3_k127_6951355_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000008014 65.0
WLSH3_k127_7140864_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 489.0
WLSH3_k127_7140864_1 Beta-Casp domain K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 461.0
WLSH3_k127_7140864_10 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
WLSH3_k127_7140864_11 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001711 266.0
WLSH3_k127_7140864_12 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000009993 235.0
WLSH3_k127_7140864_13 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000332 202.0
WLSH3_k127_7140864_14 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000007809 184.0
WLSH3_k127_7140864_15 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000000000001018 137.0
WLSH3_k127_7140864_16 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000002026 125.0
WLSH3_k127_7140864_17 Its proteolytic activity is a major factor in both periodontal tissue destruction and in evasion of host defense mechanisms K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.0000000000000002584 92.0
WLSH3_k127_7140864_18 secreted hydrolase - - - 0.000000000000002846 88.0
WLSH3_k127_7140864_19 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.0000000000003074 74.0
WLSH3_k127_7140864_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 456.0
WLSH3_k127_7140864_20 Clostripain family - - - 0.00003795 56.0
WLSH3_k127_7140864_21 NOG20192 non supervised orthologous group - - - 0.0009424 46.0
WLSH3_k127_7140864_3 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 445.0
WLSH3_k127_7140864_4 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 429.0
WLSH3_k127_7140864_5 Clp protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 348.0
WLSH3_k127_7140864_6 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 315.0
WLSH3_k127_7140864_7 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 297.0
WLSH3_k127_7140864_8 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 293.0
WLSH3_k127_7140864_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001104 267.0
WLSH3_k127_7175568_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1434.0
WLSH3_k127_7175568_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.322e-300 931.0
WLSH3_k127_7175568_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000001275 238.0
WLSH3_k127_7175568_11 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000003585 228.0
WLSH3_k127_7175568_12 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000004408 230.0
WLSH3_k127_7175568_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000002743 216.0
WLSH3_k127_7175568_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000001643 211.0
WLSH3_k127_7175568_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000001201 197.0
WLSH3_k127_7175568_16 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000007611 187.0
WLSH3_k127_7175568_17 - - - - 0.00000000000000000000000000000000000000001158 160.0
WLSH3_k127_7175568_18 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000006729 142.0
WLSH3_k127_7175568_19 Zinc transporter ZupT K07238 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0006826,GO:0006828,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015086,GO:0015087,GO:0015093,GO:0015318,GO:0015684,GO:0015691,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0034755,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070574,GO:0070838,GO:0071421,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903874 - 0.000000000000000000000000000006602 128.0
WLSH3_k127_7175568_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 612.0
WLSH3_k127_7175568_20 Matrixin - - - 0.00000000000000000006313 98.0
WLSH3_k127_7175568_21 Major Facilitator Superfamily - - - 0.00000000000007666 83.0
WLSH3_k127_7175568_22 Peptidase family C25 - - - 0.00000000947 67.0
WLSH3_k127_7175568_23 RHS Repeat - - - 0.000451 53.0
WLSH3_k127_7175568_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 426.0
WLSH3_k127_7175568_4 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 392.0
WLSH3_k127_7175568_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
WLSH3_k127_7175568_6 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003213 295.0
WLSH3_k127_7175568_7 calcium proton exchanger K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003296 280.0
WLSH3_k127_7175568_8 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003709 270.0
WLSH3_k127_7175568_9 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002807 236.0
WLSH3_k127_7277826_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000002413 191.0
WLSH3_k127_7277826_1 cell wall organization K01448 - 3.5.1.28 0.0000000000003468 84.0
WLSH3_k127_7277826_2 Pentaxin family K12287 - - 0.00000000004979 77.0
WLSH3_k127_7277826_3 Lamin Tail Domain - - - 0.0000007751 63.0
WLSH3_k127_7277826_5 Radical SAM - - - 0.0002488 47.0
WLSH3_k127_7290449_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 486.0
WLSH3_k127_7290449_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000001703 234.0
WLSH3_k127_7290449_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000003913 168.0
WLSH3_k127_7290449_3 transcriptional - - - 0.0000000000000000000000001641 108.0
WLSH3_k127_7290449_4 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.000000000000000000002437 97.0
WLSH3_k127_7335400_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0002161,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.356e-210 684.0
WLSH3_k127_7335400_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 501.0
WLSH3_k127_7335400_10 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000007074 176.0
WLSH3_k127_7335400_11 GHMP kinases N terminal domain K06982 - 2.7.1.169 0.0000000000000000000000000000000001025 144.0
WLSH3_k127_7335400_12 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000003515 115.0
WLSH3_k127_7335400_13 AMP binding - - - 0.00000000000007685 77.0
WLSH3_k127_7335400_14 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00000009838 55.0
WLSH3_k127_7335400_15 but it may be involved in stabilization of the trimeric complex - - - 0.0000006355 52.0
WLSH3_k127_7335400_2 tRNA binding K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 484.0
WLSH3_k127_7335400_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 428.0
WLSH3_k127_7335400_4 Pyruvate:ferredoxin oxidoreductase core domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 364.0
WLSH3_k127_7335400_5 methylthiotransferase activity K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 342.0
WLSH3_k127_7335400_6 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 312.0
WLSH3_k127_7335400_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 316.0
WLSH3_k127_7335400_8 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000009042 238.0
WLSH3_k127_7335400_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000006899 205.0
WLSH3_k127_7407064_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 296.0
WLSH3_k127_7407064_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007691 256.0
WLSH3_k127_7407064_2 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000000009978 157.0
WLSH3_k127_7407064_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000004401 149.0
WLSH3_k127_74560_0 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 524.0
WLSH3_k127_74560_1 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 423.0
WLSH3_k127_74560_2 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000009787 233.0
WLSH3_k127_74560_3 PFAM sodium hydrogen exchanger - - - 0.0000000000000007538 78.0
WLSH3_k127_7568944_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 4.643e-217 682.0
WLSH3_k127_7568944_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 596.0
WLSH3_k127_7568944_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000005719 178.0
WLSH3_k127_7568944_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000003706 178.0
WLSH3_k127_7568944_12 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000004487 166.0
WLSH3_k127_7568944_13 SMART Excinuclease ABC, C subunit - - - 0.00000000000000000000000000000000001602 139.0
WLSH3_k127_7568944_14 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000002576 103.0
WLSH3_k127_7568944_15 - - - - 0.0000000000000000000008936 104.0
WLSH3_k127_7568944_16 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000001587 90.0
WLSH3_k127_7568944_17 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.000000000000000004791 88.0
WLSH3_k127_7568944_18 metallopeptidase activity - - - 0.000262 54.0
WLSH3_k127_7568944_2 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 495.0
WLSH3_k127_7568944_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 474.0
WLSH3_k127_7568944_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 370.0
WLSH3_k127_7568944_5 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 322.0
WLSH3_k127_7568944_6 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 306.0
WLSH3_k127_7568944_7 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 291.0
WLSH3_k127_7568944_8 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001083 293.0
WLSH3_k127_7568944_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000006981 199.0
WLSH3_k127_7685248_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000005563 246.0
WLSH3_k127_7685248_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000003231 221.0
WLSH3_k127_7685248_2 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000007464 132.0
WLSH3_k127_7685248_3 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000000199 126.0
WLSH3_k127_7685248_4 Pfam:DUF1628 - - - 0.000000000000006928 85.0
WLSH3_k127_7685248_5 - - - - 0.00000000000001263 77.0
WLSH3_k127_7685248_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000003965 63.0
WLSH3_k127_7685248_7 DNA polymerase K02320 - 2.7.7.7 0.000009352 59.0
WLSH3_k127_7700865_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.062e-294 929.0
WLSH3_k127_7700865_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 6.019e-273 859.0
WLSH3_k127_7700865_10 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000002053 128.0
WLSH3_k127_7700865_11 GPR1/FUN34/yaaH family K07034 - - 0.0000000000000000000000000006774 121.0
WLSH3_k127_7700865_12 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000005076 109.0
WLSH3_k127_7700865_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 1.26e-206 661.0
WLSH3_k127_7700865_3 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009205 520.0
WLSH3_k127_7700865_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 509.0
WLSH3_k127_7700865_5 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 368.0
WLSH3_k127_7700865_6 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000003661 203.0
WLSH3_k127_7700865_7 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000009453 192.0
WLSH3_k127_7700865_8 Belongs to the UPF0178 family - - - 0.000000000000000000000000000000000000000000000004119 175.0
WLSH3_k127_7700865_9 Zn_pept K05996 - 3.4.17.18 0.00000000000000000000000000000000000000008558 165.0
WLSH3_k127_7708218_0 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 365.0
WLSH3_k127_7708218_1 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 299.0
WLSH3_k127_7708218_2 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.000000000000000000000000000000000000000000000000000000000000000002182 236.0
WLSH3_k127_7708218_3 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000001273 167.0
WLSH3_k127_7708218_4 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000004626 144.0
WLSH3_k127_7708218_5 ArsR transcriptional regulator - - - 0.0000000000000000000000000000001328 130.0
WLSH3_k127_7733277_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 471.0
WLSH3_k127_7733277_1 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 344.0
WLSH3_k127_7733277_2 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000000000000000000003934 134.0
WLSH3_k127_7733277_3 PQQ-like domain - - - 0.0000000000000000000000699 117.0
WLSH3_k127_7733277_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000003711 76.0
WLSH3_k127_7782317_0 PhoU domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 341.0
WLSH3_k127_7782317_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
WLSH3_k127_7782317_2 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000001336 154.0
WLSH3_k127_7879521_0 UDP binding domain K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008844 449.0
WLSH3_k127_7879521_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 434.0
WLSH3_k127_7879521_2 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 261.0
WLSH3_k127_7879521_3 - - - - 0.000000000000000000000000000000000000000439 154.0
WLSH3_k127_7897935_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 1.633e-272 861.0
WLSH3_k127_7897935_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 360.0
WLSH3_k127_7897935_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 299.0
WLSH3_k127_7897935_3 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 297.0
WLSH3_k127_7897935_4 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000002892 108.0
WLSH3_k127_7897935_5 acetyltransferase K03789 - 2.3.1.128 0.0000000000000000002524 93.0
WLSH3_k127_7897935_6 YHS domain - - - 0.0000000000000000005712 86.0
WLSH3_k127_7951479_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1585.0
WLSH3_k127_7951479_1 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 338.0
WLSH3_k127_7951479_10 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000001651 214.0
WLSH3_k127_7951479_11 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000001537 149.0
WLSH3_k127_7951479_12 PFAM NADH ubiquinone oxidoreductase, 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000001494 132.0
WLSH3_k127_7951479_13 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000001224 114.0
WLSH3_k127_7951479_14 membrane - - - 0.00000000000000000005933 103.0
WLSH3_k127_7951479_15 PFAM response regulator receiver - - - 0.00000000000000000006552 94.0
WLSH3_k127_7951479_16 - - - - 0.0000000000003683 70.0
WLSH3_k127_7951479_17 - - - - 0.00000000001081 65.0
WLSH3_k127_7951479_18 PFAM biotin lipoate A B protein ligase - - - 0.0000000002642 66.0
WLSH3_k127_7951479_19 Psort location Periplasmic, score 9.44 K07218 - - 0.0000002589 60.0
WLSH3_k127_7951479_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 333.0
WLSH3_k127_7951479_20 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000009296 57.0
WLSH3_k127_7951479_3 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 321.0
WLSH3_k127_7951479_4 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 318.0
WLSH3_k127_7951479_5 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 287.0
WLSH3_k127_7951479_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003373 273.0
WLSH3_k127_7951479_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002885 260.0
WLSH3_k127_7951479_8 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003626 273.0
WLSH3_k127_7951479_9 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000005279 238.0
WLSH3_k127_8013857_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 493.0
WLSH3_k127_8013857_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000006112 116.0
WLSH3_k127_8013857_2 GyrI-like small molecule binding domain - - - 0.000000000000000001048 89.0
WLSH3_k127_8013857_3 Protein of unknown function (DUF3795) - - - 0.000000000267 62.0
WLSH3_k127_8013857_4 Uncharacterised protein - - - 0.0000000007955 69.0
WLSH3_k127_8013857_5 Mo-molybdopterin cofactor metabolic process K03753 - - 0.00004046 47.0
WLSH3_k127_8047146_0 Phosphate uptake regulator, PhoU - - - 0.0000000000000000000000000000000000000000000000000000000001355 216.0
WLSH3_k127_8047146_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000006739 81.0
WLSH3_k127_8047146_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000004904 51.0
WLSH3_k127_806058_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 429.0
WLSH3_k127_806058_1 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 361.0
WLSH3_k127_806058_2 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 337.0
WLSH3_k127_806058_3 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000000000001741 226.0
WLSH3_k127_806058_4 Pfam:KaiC - - - 0.000000000000000000000000000002616 130.0
WLSH3_k127_806058_5 Rad51 - - - 0.000000000000000004556 85.0
WLSH3_k127_806058_6 Cold shock K03704 - - 0.0000000000000002401 80.0
WLSH3_k127_806058_7 - - - - 0.000000000000000434 81.0
WLSH3_k127_806058_8 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000003205 56.0
WLSH3_k127_806058_9 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.000008507 58.0
WLSH3_k127_812522_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001142 285.0
WLSH3_k127_812522_1 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000471 239.0
WLSH3_k127_812522_2 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000003578 160.0
WLSH3_k127_812522_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000002509 149.0
WLSH3_k127_812522_4 Acyl-protein synthetase, LuxE - - - 0.0000000000000000000003775 110.0
WLSH3_k127_812522_5 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000007772 87.0
WLSH3_k127_8156920_0 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004585 303.0
WLSH3_k127_8156920_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 309.0
WLSH3_k127_8156920_2 metallocarboxypeptidase activity K05996 - 3.4.17.18 0.0000000000000000000000000000000000000000000002165 181.0
WLSH3_k127_8156920_3 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000001269 164.0
WLSH3_k127_8156920_4 Papain family cysteine protease - - - 0.0000000000000000000000000000000000001331 155.0
WLSH3_k127_8156920_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000001005 145.0
WLSH3_k127_8156920_6 parallel beta-helix repeat K03671 - - 0.0000000002189 71.0
WLSH3_k127_8156920_7 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000799 49.0
WLSH3_k127_8284008_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 372.0
WLSH3_k127_8284008_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
WLSH3_k127_8284008_10 Protein of unknown function, DUF488 - - - 0.0008285 47.0
WLSH3_k127_8284008_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000001319 254.0
WLSH3_k127_8284008_3 COG1321 Mn-dependent transcriptional regulator K03709 - - 0.000000000000000000000000000000000000004454 151.0
WLSH3_k127_8284008_4 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000142 128.0
WLSH3_k127_8284008_5 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000007885 124.0
WLSH3_k127_8284008_6 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000007381 120.0
WLSH3_k127_8284008_7 4Fe-4S dicluster domain K03390,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000939 106.0
WLSH3_k127_8284008_8 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000974 83.0
WLSH3_k127_8284008_9 PFAM Papain family cysteine protease - - - 0.0005502 47.0
WLSH3_k127_8354001_0 PQ loop repeat K15383 - - 0.000000000000000002238 87.0
WLSH3_k127_8354001_1 - - - - 0.0000001917 56.0
WLSH3_k127_8354001_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000355 51.0
WLSH3_k127_8354001_3 - - - - 0.0005067 45.0
WLSH3_k127_8393397_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 402.0
WLSH3_k127_8393397_1 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000003204 135.0
WLSH3_k127_8456866_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.456e-268 847.0
WLSH3_k127_8456866_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 7.277e-196 629.0
WLSH3_k127_8456866_2 ATP citrate lyase, subunit 1 K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 484.0
WLSH3_k127_8456866_3 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 331.0
WLSH3_k127_8456866_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000003611 159.0
WLSH3_k127_8456866_5 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000007973 160.0
WLSH3_k127_8456866_6 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000304 126.0
WLSH3_k127_8456866_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000002257 122.0
WLSH3_k127_8456866_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000001188 88.0
WLSH3_k127_8740085_0 PQQ-like domain - - - 0.0000000000000000000000000008023 130.0
WLSH3_k127_8740085_1 Glycogen recognition site of AMP-activated protein kinase K01442 - 3.5.1.24 0.000000000000000000000000004083 124.0
WLSH3_k127_8740085_2 transcription regulator activity - - - 0.0000000000002595 70.0
WLSH3_k127_8740085_3 Laminin G domain - - - 0.000000004347 66.0
WLSH3_k127_8787678_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 507.0
WLSH3_k127_8787678_1 Oxidoreductase family, C-terminal alpha beta domain K13016 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 441.0
WLSH3_k127_8787678_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008057 369.0
WLSH3_k127_8787678_3 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 368.0
WLSH3_k127_8787678_4 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 362.0
WLSH3_k127_8787678_5 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000001676 233.0
WLSH3_k127_8787678_6 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001864 223.0
WLSH3_k127_8787678_7 Succinoglycan biosynthesis protein exoa - - - 0.0000000000000000000000000002218 123.0
WLSH3_k127_8787678_8 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000001567 81.0
WLSH3_k127_8955643_0 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 620.0
WLSH3_k127_8955643_1 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 400.0
WLSH3_k127_8955643_2 PFAM zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002435 251.0
WLSH3_k127_8955643_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002883 246.0
WLSH3_k127_8955643_4 FeoA K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000000944 237.0
WLSH3_k127_8955643_5 transcriptional regulator, AsnC family - - - 0.000000000000000000000000000000000000000000000000008973 186.0
WLSH3_k127_8955643_6 Belongs to the Fur family K03711 - - 0.000000003617 63.0
WLSH3_k127_8955643_7 Transglutaminase-like superfamily - - - 0.000449 52.0
WLSH3_k127_8999904_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 564.0
WLSH3_k127_8999904_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 379.0
WLSH3_k127_8999904_2 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 362.0
WLSH3_k127_8999904_3 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 342.0
WLSH3_k127_8999904_4 lycopene cyclase - - - 0.000000000000000000000000000000000000000000000000000007674 198.0
WLSH3_k127_8999904_5 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.00000000000000000002646 93.0
WLSH3_k127_9018263_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 477.0
WLSH3_k127_9018263_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 292.0
WLSH3_k127_9018263_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000361 215.0
WLSH3_k127_9018263_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000002097 207.0
WLSH3_k127_9018263_4 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.0000000000000000000000000000000000000000000000000000001069 203.0
WLSH3_k127_9018263_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000001047 126.0
WLSH3_k127_9018263_6 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000002349 104.0
WLSH3_k127_9018263_7 reductase - - - 0.00000000000000000031 100.0
WLSH3_k127_9018263_8 Radical SAM - - - 0.0001514 48.0
WLSH3_k127_9018263_9 chitin catabolic process K01183 - 3.2.1.14 0.0009541 50.0
WLSH3_k127_9132688_0 Thioredoxin domain K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000001766 216.0
WLSH3_k127_9132688_1 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000005141 186.0
WLSH3_k127_9132688_2 Sulphur oxygenase reductase K03151,K16952 - 1.13.11.55,2.8.1.4 0.0000000000000000000000000000000001078 137.0
WLSH3_k127_9132688_3 Glutaredoxin - - - 0.0000000000000000000009342 97.0
WLSH3_k127_9177214_0 amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 518.0
WLSH3_k127_9177214_1 Flavodoxin K03839 - - 0.0000000000000000000000000000000001285 138.0
WLSH3_k127_9177214_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000001021 76.0
WLSH3_k127_9177214_3 Protein of unknown function (DUF1624) - - - 0.000000001422 62.0
WLSH3_k127_9177214_4 Flavodoxin K03809 - 1.6.5.2 0.0009458 48.0
WLSH3_k127_9183338_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 529.0
WLSH3_k127_9183338_1 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000001281 218.0
WLSH3_k127_9183338_3 membrane-associated protein domain - - - 0.00000000004317 76.0
WLSH3_k127_9183338_4 membrane-associated protein domain - - - 0.000000008703 68.0
WLSH3_k127_9183338_5 deoxyhypusine monooxygenase activity - - - 0.000001509 54.0
WLSH3_k127_9294243_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009346 548.0
WLSH3_k127_9294243_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 481.0
WLSH3_k127_9294243_10 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000002564 123.0
WLSH3_k127_9294243_11 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000002222 109.0
WLSH3_k127_9294243_12 Circadian clock protein KaiC - - - 0.00000000000000000000006801 108.0
WLSH3_k127_9294243_13 structural constituent of ribosome K02974 - - 0.000000000000000000001229 99.0
WLSH3_k127_9294243_14 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000002762 79.0
WLSH3_k127_9294243_15 proteins of PilT N-term. Vapc superfamily K07158 - - 0.0000000000000006306 82.0
WLSH3_k127_9294243_16 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000002151 71.0
WLSH3_k127_9294243_17 Histidine kinase - - - 0.000000000003399 79.0
WLSH3_k127_9294243_18 methyltransferase activity - - - 0.000000000004225 72.0
WLSH3_k127_9294243_2 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 315.0
WLSH3_k127_9294243_3 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 277.0
WLSH3_k127_9294243_4 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000001805 206.0
WLSH3_k127_9294243_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000002322 217.0
WLSH3_k127_9294243_6 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000005019 163.0
WLSH3_k127_9294243_7 Radical SAM - - - 0.00000000000000000000000000000000000000000101 166.0
WLSH3_k127_9294243_8 Diguanylate cyclase - - - 0.0000000000000000000000000000001509 142.0
WLSH3_k127_9294243_9 KaiC - - - 0.000000000000000000000000000001665 130.0
WLSH3_k127_9302213_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 474.0
WLSH3_k127_9302213_1 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 431.0
WLSH3_k127_9302213_10 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000005567 228.0
WLSH3_k127_9302213_11 - - - - 0.00000000000000000000000000000000000000000000000000000000001846 215.0
WLSH3_k127_9302213_12 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000002045 196.0
WLSH3_k127_9302213_13 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000000002854 189.0
WLSH3_k127_9302213_14 membrane K09133 - - 0.0000000000000000000000000000000000001698 156.0
WLSH3_k127_9302213_15 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000004651 140.0
WLSH3_k127_9302213_16 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000008909 126.0
WLSH3_k127_9302213_17 nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module K07060 - - 0.000000000000000000000364 101.0
WLSH3_k127_9302213_18 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000008331 78.0
WLSH3_k127_9302213_19 cell adhesion involved in biofilm formation - - - 0.00000000003243 75.0
WLSH3_k127_9302213_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 404.0
WLSH3_k127_9302213_20 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000152 60.0
WLSH3_k127_9302213_21 protein conserved in archaea K09723 - - 0.0000001527 60.0
WLSH3_k127_9302213_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 367.0
WLSH3_k127_9302213_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 336.0
WLSH3_k127_9302213_5 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 295.0
WLSH3_k127_9302213_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 284.0
WLSH3_k127_9302213_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007767 272.0
WLSH3_k127_9302213_8 Diphthamide K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000001084 274.0
WLSH3_k127_9302213_9 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006772 253.0
WLSH3_k127_9369091_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 545.0
WLSH3_k127_9369091_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 385.0
WLSH3_k127_9369091_10 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.00000000000000000000135 95.0
WLSH3_k127_9369091_11 PFAM regulatory protein, ArsR K03892,K21903 - - 0.0000000000000005364 80.0
WLSH3_k127_9369091_12 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000001825 83.0
WLSH3_k127_9369091_14 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000005847 61.0
WLSH3_k127_9369091_15 Winged helix-turn-helix domain (DUF2582) - - - 0.0000002494 57.0
WLSH3_k127_9369091_16 Winged helix-turn-helix domain (DUF2582) - - - 0.000003021 54.0
WLSH3_k127_9369091_17 Biotin-protein ligase, N terminal - - - 0.00001282 57.0
WLSH3_k127_9369091_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 330.0
WLSH3_k127_9369091_3 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001028 265.0
WLSH3_k127_9369091_4 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000009987 238.0
WLSH3_k127_9369091_5 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000003931 169.0
WLSH3_k127_9369091_6 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000007102 164.0
WLSH3_k127_9369091_7 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000003821 166.0
WLSH3_k127_9369091_8 TIGRFAM segregation and condensation protein B K06024 - - 0.000000000000000000000000000000001691 136.0
WLSH3_k127_9369091_9 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000001027 126.0
WLSH3_k127_9406571_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000009174 192.0
WLSH3_k127_9406571_1 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000467 164.0
WLSH3_k127_9406571_10 Winged helix-turn-helix domain (DUF2582) - - - 0.0000002339 57.0
WLSH3_k127_9406571_11 Major Facilitator Superfamily - - - 0.000004709 59.0
WLSH3_k127_9406571_12 Phage integrase family - - - 0.0005953 46.0
WLSH3_k127_9406571_2 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000001764 150.0
WLSH3_k127_9406571_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.0000000000000000000000000002161 117.0
WLSH3_k127_9406571_4 serine threonine protein kinase - - - 0.00000000000000000000001815 110.0
WLSH3_k127_9406571_5 Fibronectin type III domain - - - 0.00000000000000000002591 104.0
WLSH3_k127_9406571_6 - - - - 0.0000000000005427 75.0
WLSH3_k127_9406571_7 TIGRFAM molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000002229 72.0
WLSH3_k127_9406571_8 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000000002665 73.0
WLSH3_k127_9406571_9 Winged helix-turn-helix domain (DUF2582) - - - 0.0000001711 58.0
WLSH3_k127_943871_0 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 347.0
WLSH3_k127_943871_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002942 266.0
WLSH3_k127_943871_2 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000002864 181.0
WLSH3_k127_943871_3 Iron-sulfur cluster-binding domain - - - 0.0000008843 53.0
WLSH3_k127_9471012_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 471.0
WLSH3_k127_9471012_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 398.0
WLSH3_k127_9471012_10 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001214 274.0
WLSH3_k127_9471012_11 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000789 262.0
WLSH3_k127_9471012_12 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000009027 255.0
WLSH3_k127_9471012_13 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002508 255.0
WLSH3_k127_9471012_14 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002917 222.0
WLSH3_k127_9471012_15 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000005707 218.0
WLSH3_k127_9471012_16 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000000001013 218.0
WLSH3_k127_9471012_17 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000124 190.0
WLSH3_k127_9471012_18 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000002037 177.0
WLSH3_k127_9471012_19 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001257 163.0
WLSH3_k127_9471012_2 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 372.0
WLSH3_k127_9471012_20 Phosphoglycolate phosphatase K01091 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.00000000000000000002748 98.0
WLSH3_k127_9471012_21 Lrp/AsnC ligand binding domain - - - 0.00000000000000000005725 92.0
WLSH3_k127_9471012_22 PFAM regulatory protein, ArsR - - - 0.000000000000000433 87.0
WLSH3_k127_9471012_23 Domain of unknown function (DUF1610) K07580 - - 0.000000000000001956 77.0
WLSH3_k127_9471012_24 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000005704 75.0
WLSH3_k127_9471012_25 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000001336 62.0
WLSH3_k127_9471012_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 373.0
WLSH3_k127_9471012_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 363.0
WLSH3_k127_9471012_5 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 362.0
WLSH3_k127_9471012_6 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 313.0
WLSH3_k127_9471012_7 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 308.0
WLSH3_k127_9471012_8 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 297.0
WLSH3_k127_9471012_9 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007853 285.0
WLSH3_k127_9655536_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 374.0
WLSH3_k127_9655536_1 L-ribulose-5-phosphate 4-epimerase K01628 - 4.1.2.17 0.000004003 56.0
WLSH3_k127_9655536_2 GvpD gas vesicle protein - - - 0.00000819 53.0
WLSH3_k127_9666171_0 helix_turn_helix ASNC type - - - 0.00003237 53.0
WLSH3_k127_9666171_1 Laminin G domain - - - 0.0002881 46.0
WLSH3_k127_9666171_2 cell wall organization - - - 0.0005295 51.0
WLSH3_k127_9852905_0 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000005436 180.0
WLSH3_k127_9852905_1 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000004112 102.0
WLSH3_k127_9852905_2 PFAM Fibronectin type III domain - - - 0.0006186 52.0
WLSH3_k127_9963892_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 561.0
WLSH3_k127_9963892_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 305.0
WLSH3_k127_9963892_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000002356 223.0
WLSH3_k127_9963892_3 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000006197 108.0
WLSH3_k127_9963892_4 - - - - 0.00000000000000007637 82.0
WLSH3_k127_9963892_5 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000001953 73.0
WLSH3_k127_9963892_6 - - - - 0.00000000000004919 81.0
WLSH3_k127_9963892_7 PFAM PKD domain - - - 0.000123 48.0
WLSH3_k127_9980591_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 593.0
WLSH3_k127_9980591_1 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009674 530.0
WLSH3_k127_9980591_2 PFAM type II secretion system protein E K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 501.0
WLSH3_k127_9980591_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 405.0
WLSH3_k127_9994863_0 PFAM Integrase, catalytic core - - - 0.000000000000008348 85.0