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Overview

ID MAG04398
Name XH1_bin.47
Sample SMP0118
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family Methanospirillaceae
Genus MVRE01
Species
Assembly information
Completeness (%) 73.98
Contamination (%) 2.49
GC content (%) 54.0
N50 (bp) 40,674
Genome size (bp) 1,382,156

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1403

Gene name Description KEGG GOs EC E-value Score Sequence
XH1_k127_1136486_0 DEAD DEAH box helicase domain protein K03725 - - 0.0 1096.0
XH1_k127_1136486_1 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 462.0
XH1_k127_1136486_2 ArsR transcriptional regulator - - - 0.000000000000000000000001663 105.0
XH1_k127_1255536_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 587.0
XH1_k127_1255536_1 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 376.0
XH1_k127_1255536_2 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008434 279.0
XH1_k127_1259824_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1260.0
XH1_k127_1259824_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 8.415e-245 760.0
XH1_k127_1259824_10 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000001257 208.0
XH1_k127_1259824_11 - - - - 0.0000000000000000000000000000000000000000000000000002144 191.0
XH1_k127_1259824_12 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000008177 177.0
XH1_k127_1259824_13 - - - - 0.000000000000000000000000318 109.0
XH1_k127_1259824_14 - - - - 0.0000000000001404 72.0
XH1_k127_1259824_2 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 525.0
XH1_k127_1259824_3 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 436.0
XH1_k127_1259824_4 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 410.0
XH1_k127_1259824_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 399.0
XH1_k127_1259824_6 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 407.0
XH1_k127_1259824_7 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 293.0
XH1_k127_1259824_8 Domain of unknown function (DUF1724) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001582 251.0
XH1_k127_1259824_9 Protein of unknown function (DUF1648) - - - 0.0000000000000000000000000000000000000000000000000000000000001381 218.0
XH1_k127_1432219_0 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 491.0
XH1_k127_1432219_1 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 312.0
XH1_k127_1432219_2 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001002 259.0
XH1_k127_1432219_3 Belongs to the UPF0212 family K09731 - - 0.00000000000000000000000000000000000000000000000000005066 188.0
XH1_k127_1432219_4 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000002022 97.0
XH1_k127_1432219_5 Family of unknown function (DUF5350) - - - 0.0000000000339 65.0
XH1_k127_1432849_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 1.472e-207 650.0
XH1_k127_1432849_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 605.0
XH1_k127_1432849_10 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 295.0
XH1_k127_1432849_11 PFAM peptidase zinc-dependent K06974 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007197 274.0
XH1_k127_1432849_12 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003578 266.0
XH1_k127_1432849_13 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000000000002238 195.0
XH1_k127_1432849_14 Belongs to the UPF0146 family K09713 - - 0.00000000000000000000000000000000000000000000008899 171.0
XH1_k127_1432849_15 transcription factor (CBF NF-Y) - - - 0.00000000000000000000000000001049 121.0
XH1_k127_1432849_2 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 573.0
XH1_k127_1432849_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 450.0
XH1_k127_1432849_4 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 361.0
XH1_k127_1432849_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 351.0
XH1_k127_1432849_6 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 347.0
XH1_k127_1432849_7 secretion by the type IV secretion system K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 349.0
XH1_k127_1432849_8 PFAM TM2 domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 329.0
XH1_k127_1432849_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 325.0
XH1_k127_1549069_0 TIGRFAM acetate--CoA ligase K01895 - 6.2.1.1 0.0 1107.0
XH1_k127_1549069_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0 1055.0
XH1_k127_1549069_10 PFAM Aminotransferase class I and II K10907 - - 2.515e-202 634.0
XH1_k127_1549069_11 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 1.241e-198 624.0
XH1_k127_1549069_12 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 602.0
XH1_k127_1549069_13 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 595.0
XH1_k127_1549069_14 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 589.0
XH1_k127_1549069_15 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 597.0
XH1_k127_1549069_16 involved in cell wall biogenesis K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 556.0
XH1_k127_1549069_17 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 554.0
XH1_k127_1549069_18 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 518.0
XH1_k127_1549069_19 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 520.0
XH1_k127_1549069_2 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.079e-300 936.0
XH1_k127_1549069_20 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 514.0
XH1_k127_1549069_21 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007036 493.0
XH1_k127_1549069_22 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 484.0
XH1_k127_1549069_23 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 439.0
XH1_k127_1549069_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 438.0
XH1_k127_1549069_25 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 421.0
XH1_k127_1549069_26 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 402.0
XH1_k127_1549069_27 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 407.0
XH1_k127_1549069_28 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 397.0
XH1_k127_1549069_29 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 386.0
XH1_k127_1549069_3 SMART Elongator protein 3 MiaB NifB - - - 1.814e-296 919.0
XH1_k127_1549069_30 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 373.0
XH1_k127_1549069_31 nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 368.0
XH1_k127_1549069_32 PFAM DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 364.0
XH1_k127_1549069_33 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 344.0
XH1_k127_1549069_34 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 321.0
XH1_k127_1549069_35 Pas domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 346.0
XH1_k127_1549069_36 KH domain protein K06961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 306.0
XH1_k127_1549069_37 O-methyltransferase K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 309.0
XH1_k127_1549069_38 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 317.0
XH1_k127_1549069_39 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 297.0
XH1_k127_1549069_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 9.683e-275 848.0
XH1_k127_1549069_40 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 297.0
XH1_k127_1549069_41 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 296.0
XH1_k127_1549069_42 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 283.0
XH1_k127_1549069_43 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001596 284.0
XH1_k127_1549069_44 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
XH1_k127_1549069_45 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002897 275.0
XH1_k127_1549069_46 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005572 263.0
XH1_k127_1549069_47 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002279 257.0
XH1_k127_1549069_48 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000252 250.0
XH1_k127_1549069_49 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
XH1_k127_1549069_5 Involved in regulation of DNA replication K10725 - - 1.097e-253 787.0
XH1_k127_1549069_50 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
XH1_k127_1549069_51 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008048 231.0
XH1_k127_1549069_52 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000002697 224.0
XH1_k127_1549069_53 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
XH1_k127_1549069_54 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000001682 214.0
XH1_k127_1549069_55 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000001789 213.0
XH1_k127_1549069_56 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000004398 190.0
XH1_k127_1549069_57 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000005247 185.0
XH1_k127_1549069_58 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000000000000000000000000000000006464 166.0
XH1_k127_1549069_59 Zinc-ribbon containing domain - - - 0.000000000000000000000000000000000000000003097 154.0
XH1_k127_1549069_6 PFAM aminotransferase class V - - - 3.61e-208 651.0
XH1_k127_1549069_60 involved in cell wall biogenesis K00721 - 2.4.1.83 0.000000000000000000000000000000000000008204 154.0
XH1_k127_1549069_61 - - - - 0.0000000000000000000000000000006039 125.0
XH1_k127_1549069_62 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000000001438 123.0
XH1_k127_1549069_63 chorismate mutase K04093 - 5.4.99.5 0.000000000000000000000000001787 115.0
XH1_k127_1549069_64 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.00000000000000000000001098 109.0
XH1_k127_1549069_65 Belongs to the UPF0248 family K09715 - - 0.0000000000000000000004906 97.0
XH1_k127_1549069_66 - - - - 0.0000000000000000000006592 103.0
XH1_k127_1549069_67 Protein of unknown function (DUF3795) - - - 0.000000000000000000001683 95.0
XH1_k127_1549069_68 Belongs to the UPF0434 family - - - 0.0000000000000000001491 89.0
XH1_k127_1549069_69 Protein of unknown function (DUF2769) - - - 0.0000000000000000003272 91.0
XH1_k127_1549069_7 Predicted membrane protein (DUF2207) - - - 5.745e-207 660.0
XH1_k127_1549069_70 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.00000000000000002297 83.0
XH1_k127_1549069_71 PFAM YHS domain - - - 0.0000000000000002721 81.0
XH1_k127_1549069_72 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000000000089 85.0
XH1_k127_1549069_73 Belongs to the ompA family - - - 0.00000000000002319 88.0
XH1_k127_1549069_74 Protein of unknown function (DUF3795) - - - 0.00000000006204 63.0
XH1_k127_1549069_75 translation initiation factor activity - - - 0.0000000004761 74.0
XH1_k127_1549069_76 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000001656 56.0
XH1_k127_1549069_77 TIGRFAM lysine 2,3-aminomutase YodO family protein - - - 0.0002177 44.0
XH1_k127_1549069_8 COG0477 Permeases of the major facilitator superfamily K08177 - - 6.475e-207 650.0
XH1_k127_1549069_9 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 8.603e-203 633.0
XH1_k127_167050_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1652.0
XH1_k127_167050_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1132.0
XH1_k127_167050_10 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000005737 224.0
XH1_k127_167050_11 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000001159 161.0
XH1_k127_167050_13 - - - - 0.000000000000000000000000000002275 129.0
XH1_k127_167050_14 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000411 99.0
XH1_k127_167050_2 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 1.037e-257 798.0
XH1_k127_167050_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.176e-229 721.0
XH1_k127_167050_4 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 609.0
XH1_k127_167050_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 496.0
XH1_k127_167050_6 membrane-associated protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 305.0
XH1_k127_167050_7 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000972 286.0
XH1_k127_167050_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001555 246.0
XH1_k127_167050_9 PFAM RDD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 243.0
XH1_k127_1747829_0 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 594.0
XH1_k127_1747829_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 489.0
XH1_k127_1747829_10 peptidase activity, acting on L-amino acid peptides K07004,K09955,K12567,K21449 - 2.7.11.1 0.000003515 57.0
XH1_k127_1747829_2 Pas domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 427.0
XH1_k127_1747829_3 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 442.0
XH1_k127_1747829_4 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 363.0
XH1_k127_1747829_5 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 376.0
XH1_k127_1747829_6 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000002373 219.0
XH1_k127_1747829_7 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000000000000000009174 170.0
XH1_k127_1747829_8 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000000000000000000000000000000000005524 184.0
XH1_k127_1747829_9 small multi-drug export - - - 0.000000000000000008068 91.0
XH1_k127_1784622_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.103e-273 846.0
XH1_k127_1784622_1 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 2.177e-272 844.0
XH1_k127_1784622_10 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 497.0
XH1_k127_1784622_11 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 446.0
XH1_k127_1784622_12 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 440.0
XH1_k127_1784622_13 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 433.0
XH1_k127_1784622_14 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 427.0
XH1_k127_1784622_15 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 428.0
XH1_k127_1784622_16 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 424.0
XH1_k127_1784622_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 436.0
XH1_k127_1784622_18 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 400.0
XH1_k127_1784622_19 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 398.0
XH1_k127_1784622_2 Domain of unknown function (DUF3821) - - - 4.031e-263 846.0
XH1_k127_1784622_20 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 379.0
XH1_k127_1784622_21 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 368.0
XH1_k127_1784622_22 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 344.0
XH1_k127_1784622_23 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 320.0
XH1_k127_1784622_24 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 308.0
XH1_k127_1784622_25 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 296.0
XH1_k127_1784622_26 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 288.0
XH1_k127_1784622_27 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001616 279.0
XH1_k127_1784622_28 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005378 279.0
XH1_k127_1784622_29 amino acid K16263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001151 288.0
XH1_k127_1784622_3 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 1.09e-216 673.0
XH1_k127_1784622_30 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000383 275.0
XH1_k127_1784622_31 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002517 278.0
XH1_k127_1784622_32 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006357 273.0
XH1_k127_1784622_33 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009796 268.0
XH1_k127_1784622_34 Oxidoreductase, molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002789 261.0
XH1_k127_1784622_35 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006382 256.0
XH1_k127_1784622_36 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 249.0
XH1_k127_1784622_37 binds to the 23S rRNA K02885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002377 246.0
XH1_k127_1784622_38 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005579 244.0
XH1_k127_1784622_39 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000339 235.0
XH1_k127_1784622_4 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 6.282e-199 621.0
XH1_k127_1784622_40 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000000000000000000000000000000000000000000000000000004146 238.0
XH1_k127_1784622_41 PFAM sigma-70 region 4 domain protein K09714 - - 0.00000000000000000000000000000000000000000000000000000000000000000002087 233.0
XH1_k127_1784622_42 membrane - - - 0.0000000000000000000000000000000000000000000000000000000009996 209.0
XH1_k127_1784622_43 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000000000000000000000001166 202.0
XH1_k127_1784622_44 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000009984 192.0
XH1_k127_1784622_45 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000003681 190.0
XH1_k127_1784622_46 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000002044 183.0
XH1_k127_1784622_47 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.0000000000000000000000000000000000000000000000000304 183.0
XH1_k127_1784622_48 PFAM Ribosomal protein K02912 - - 0.000000000000000000000000000000000000005639 155.0
XH1_k127_1784622_49 metallopeptidase activity - - - 0.0000000000000000000000000000000000002932 149.0
XH1_k127_1784622_5 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 578.0
XH1_k127_1784622_50 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.00000000000000000000000000000000003125 135.0
XH1_k127_1784622_51 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000000000000103 122.0
XH1_k127_1784622_52 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000000000000000003081 114.0
XH1_k127_1784622_53 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.0000000000000000000000001351 106.0
XH1_k127_1784622_54 - - - - 0.000000002085 61.0
XH1_k127_1784622_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 572.0
XH1_k127_1784622_7 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 561.0
XH1_k127_1784622_8 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 568.0
XH1_k127_1784622_9 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 512.0
XH1_k127_1831347_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1170.0
XH1_k127_1831347_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07652 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 583.0
XH1_k127_1831347_2 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 463.0
XH1_k127_1831347_3 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 323.0
XH1_k127_1831347_4 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 312.0
XH1_k127_1831347_5 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000001378 188.0
XH1_k127_1831347_6 - - - - 0.0000000000000000000000000000000002082 133.0
XH1_k127_1831347_8 TIR domain - - - 0.0000000001306 69.0
XH1_k127_2211176_0 PFAM type II secretion system protein E K07332 - - 0.0 1041.0
XH1_k127_2211176_1 type II secretion system protein K07333 - - 2.117e-209 664.0
XH1_k127_2211176_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 511.0
XH1_k127_2211176_3 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 395.0
XH1_k127_2211176_4 in RNase L inhibitor, RLI K06174 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 325.0
XH1_k127_2211176_5 - - - - 0.0000000000000000000002819 110.0
XH1_k127_2211176_6 Archaeal flagellar protein F K07329 - - 0.00003094 54.0
XH1_k127_2231470_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1388.0
XH1_k127_2231470_1 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1345.0
XH1_k127_2231470_10 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 396.0
XH1_k127_2231470_11 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 371.0
XH1_k127_2231470_12 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 317.0
XH1_k127_2231470_13 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000000001467 176.0
XH1_k127_2231470_14 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000204 67.0
XH1_k127_2231470_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1095.0
XH1_k127_2231470_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.439e-262 814.0
XH1_k127_2231470_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.009e-244 759.0
XH1_k127_2231470_5 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 498.0
XH1_k127_2231470_6 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 488.0
XH1_k127_2231470_7 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 471.0
XH1_k127_2231470_8 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 405.0
XH1_k127_2231470_9 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 404.0
XH1_k127_2235031_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1189.0
XH1_k127_2235031_1 Conserved region in glutamate synthase - - - 2.532e-293 905.0
XH1_k127_2235031_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 567.0
XH1_k127_2235031_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 564.0
XH1_k127_2235031_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 534.0
XH1_k127_2235031_5 TIGRFAM PAS sensor protein K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 482.0
XH1_k127_2235031_6 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003254 263.0
XH1_k127_2235031_7 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000001301 96.0
XH1_k127_2279928_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.0 1104.0
XH1_k127_2279928_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1080.0
XH1_k127_2279928_10 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 387.0
XH1_k127_2279928_11 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 293.0
XH1_k127_2279928_12 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006125 267.0
XH1_k127_2279928_13 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000903 221.0
XH1_k127_2279928_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000001932 184.0
XH1_k127_2279928_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.0000000000000000000000000000000000000000366 153.0
XH1_k127_2279928_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 7.395e-269 829.0
XH1_k127_2279928_3 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 3.673e-235 730.0
XH1_k127_2279928_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 4.073e-234 726.0
XH1_k127_2279928_5 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 599.0
XH1_k127_2279928_6 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 534.0
XH1_k127_2279928_7 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 458.0
XH1_k127_2279928_8 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 436.0
XH1_k127_2279928_9 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 379.0
XH1_k127_2336985_0 Belongs to the MCM family K10726 - - 1.853e-266 824.0
XH1_k127_2336985_1 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 308.0
XH1_k127_2336985_2 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000001799 138.0
XH1_k127_2516734_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1199.0
XH1_k127_2516734_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 414.0
XH1_k127_2516734_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.00000000000000000000000000000000000000000000000000000000000000000002068 237.0
XH1_k127_2544230_0 Predicted membrane protein (DUF2070) K08979 - - 5.017e-208 656.0
XH1_k127_2544230_1 permease K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 363.0
XH1_k127_2544230_2 Putative transposase DNA-binding domain K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 285.0
XH1_k127_2544230_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000003515 221.0
XH1_k127_2556292_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0 1046.0
XH1_k127_2556292_1 COG1668 ABC-type Na efflux pump, permease component - - - 1.791e-270 843.0
XH1_k127_2556292_10 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 395.0
XH1_k127_2556292_11 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 339.0
XH1_k127_2556292_12 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007171 270.0
XH1_k127_2556292_13 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000004942 218.0
XH1_k127_2556292_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000001546 218.0
XH1_k127_2556292_15 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.0000000000000000000000000000000000000000000000000000000009688 204.0
XH1_k127_2556292_16 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000000000000000000000000000000004192 198.0
XH1_k127_2556292_17 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000000000000000002838 197.0
XH1_k127_2556292_18 - - - - 0.00000000000000000000000000000000000000000000002053 175.0
XH1_k127_2556292_19 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000005115 149.0
XH1_k127_2556292_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 2.293e-210 667.0
XH1_k127_2556292_20 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000000000000000000000006509 126.0
XH1_k127_2556292_21 Sugar efflux transporter for intercellular exchange K15383 - - 0.000000000000000000000000000008944 120.0
XH1_k127_2556292_22 RNA-binding protein involved in rRNA processing K07569 - - 0.00000000000000000000000000004411 118.0
XH1_k127_2556292_23 TIR domain - - - 0.000000000000000000000000000991 118.0
XH1_k127_2556292_24 Ion channel - - - 0.000000000000000002165 98.0
XH1_k127_2556292_25 - K16923 - - 0.000000000000000002884 98.0
XH1_k127_2556292_26 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000005531 71.0
XH1_k127_2556292_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 1.602e-209 652.0
XH1_k127_2556292_4 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 530.0
XH1_k127_2556292_5 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 499.0
XH1_k127_2556292_6 Radical SAM ThiC family K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007006 435.0
XH1_k127_2556292_7 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 431.0
XH1_k127_2556292_8 Type I restriction-modification system methyltransferase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 430.0
XH1_k127_2556292_9 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 405.0
XH1_k127_280050_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 604.0
XH1_k127_280050_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 353.0
XH1_k127_280050_2 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 338.0
XH1_k127_280050_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 289.0
XH1_k127_280050_4 membrane K09167 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001693 276.0
XH1_k127_280050_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.00000000003327 75.0
XH1_k127_280050_7 - - - - 0.0000004555 58.0
XH1_k127_3056892_0 Protein of unknown function (DUF460) K09150 - - 1.8e-306 950.0
XH1_k127_3056892_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 7.882e-261 811.0
XH1_k127_3056892_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 438.0
XH1_k127_3056892_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 409.0
XH1_k127_3056892_12 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 409.0
XH1_k127_3056892_13 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 396.0
XH1_k127_3056892_14 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 387.0
XH1_k127_3056892_15 WD-40 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 402.0
XH1_k127_3056892_16 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 374.0
XH1_k127_3056892_17 Rio2, N-terminal K07179 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 370.0
XH1_k127_3056892_18 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 341.0
XH1_k127_3056892_19 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 340.0
XH1_k127_3056892_2 ATPase family associated with various cellular activities (AAA) - - - 1.847e-242 757.0
XH1_k127_3056892_20 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 328.0
XH1_k127_3056892_21 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 315.0
XH1_k127_3056892_22 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000046 276.0
XH1_k127_3056892_23 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000004865 228.0
XH1_k127_3056892_24 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000005476 229.0
XH1_k127_3056892_25 PFAM transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000006861 219.0
XH1_k127_3056892_26 membrane - - - 0.00000000000000000000000000000000000000000000000000000000147 215.0
XH1_k127_3056892_27 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04068 - 1.97.1.4 0.00000000000000000000000000000000000000000000000003815 184.0
XH1_k127_3056892_28 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000003571 177.0
XH1_k127_3056892_29 - - - - 0.000000000000000000000000000000000000000005184 156.0
XH1_k127_3056892_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 3.615e-202 636.0
XH1_k127_3056892_31 - - - - 0.000000000000000000009227 93.0
XH1_k127_3056892_32 - - - - 0.00000000000001176 79.0
XH1_k127_3056892_33 Protein tyrosine kinase - - - 0.00000004875 66.0
XH1_k127_3056892_34 Protein of unknown function (DUF2997) - - - 0.00000007365 56.0
XH1_k127_3056892_4 PFAM TrkA-N domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 580.0
XH1_k127_3056892_5 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 529.0
XH1_k127_3056892_6 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 527.0
XH1_k127_3056892_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 511.0
XH1_k127_3056892_8 Radical SAM ThiC family K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005011 474.0
XH1_k127_3056892_9 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 481.0
XH1_k127_3156761_0 PFAM Cation K03498 - - 8.506e-217 683.0
XH1_k127_3156761_1 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 346.0
XH1_k127_3156761_10 Predicted membrane protein (DUF2109) K14094 - - 0.0000000000000000000008496 104.0
XH1_k127_3156761_11 NiFe -hydrogenase-3-type complex Eha, membrane protein EhaE K14096 - - 0.0000000000000000003791 93.0
XH1_k127_3156761_12 Histidine kinase - - - 0.000000000000000001759 93.0
XH1_k127_3156761_13 His Kinase A (phosphoacceptor) domain K02030 - - 0.00000000000004797 79.0
XH1_k127_3156761_14 Predicted membrane protein (DUF2108) K14095 - - 0.00000000000006698 75.0
XH1_k127_3156761_15 - - - - 0.00000006841 62.0
XH1_k127_3156761_2 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
XH1_k127_3156761_3 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000831 280.0
XH1_k127_3156761_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003964 243.0
XH1_k127_3156761_5 - K14093 - - 0.00000000000000000000000000000000000000000000000000000000000000001448 231.0
XH1_k127_3156761_6 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.000000000000000000000000000000000000000000000000000009785 196.0
XH1_k127_3156761_7 Predicted membrane protein (DUF2105) K14098 - - 0.0000000000000000000000000000000000000000000000000002672 198.0
XH1_k127_3156761_8 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.0000000000000000000000000000000000000000000000001576 181.0
XH1_k127_3156761_9 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.00000000000000000000003746 106.0
XH1_k127_3405272_0 Belongs to the RtcB family K14415 - 6.5.1.3 2.21e-207 650.0
XH1_k127_3405272_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 282.0
XH1_k127_3429762_0 Uncharacterized membrane protein (DUF2298) - - - 7.549e-276 863.0
XH1_k127_3429762_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.179e-265 820.0
XH1_k127_3429762_10 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 480.0
XH1_k127_3429762_11 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 462.0
XH1_k127_3429762_12 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 454.0
XH1_k127_3429762_13 Belongs to the UPF0285 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 456.0
XH1_k127_3429762_14 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 455.0
XH1_k127_3429762_15 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 391.0
XH1_k127_3429762_16 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 326.0
XH1_k127_3429762_17 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 312.0
XH1_k127_3429762_18 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 311.0
XH1_k127_3429762_19 PFAM Glycosyl transferase family 2 K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 307.0
XH1_k127_3429762_2 PFAM glycosyl transferase family 39 - - - 2.639e-248 776.0
XH1_k127_3429762_20 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000408 281.0
XH1_k127_3429762_21 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009959 272.0
XH1_k127_3429762_22 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001031 270.0
XH1_k127_3429762_23 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001943 268.0
XH1_k127_3429762_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000105 259.0
XH1_k127_3429762_25 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000116 237.0
XH1_k127_3429762_26 PFAM Phosphatidylglycerophosphatase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000002467 234.0
XH1_k127_3429762_27 Domain of unknown function (DUF3821) - - - 0.0000000000000000000000000000000000000000000000000000000000000000249 236.0
XH1_k127_3429762_28 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000000000000000000001594 216.0
XH1_k127_3429762_29 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000000002575 208.0
XH1_k127_3429762_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 6.423e-233 723.0
XH1_k127_3429762_30 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000003334 172.0
XH1_k127_3429762_31 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000009304 177.0
XH1_k127_3429762_32 - - - - 0.0000000000000000000000000000000000000000001229 168.0
XH1_k127_3429762_33 - - - - 0.0000000000000000000000000000000000001706 143.0
XH1_k127_3429762_34 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000000000006455 139.0
XH1_k127_3429762_35 Binds to the 23S rRNA K02896 - - 0.00000000000000000000000000002761 117.0
XH1_k127_3429762_4 Involved in cell shape control K22222 - - 5.044e-230 715.0
XH1_k127_3429762_5 Involved in regulation of DNA replication K10725 - - 9.898e-194 610.0
XH1_k127_3429762_6 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 593.0
XH1_k127_3429762_7 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 584.0
XH1_k127_3429762_8 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 565.0
XH1_k127_3429762_9 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 534.0
XH1_k127_3548199_0 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 548.0
XH1_k127_3548199_1 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 348.0
XH1_k127_3548199_2 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000004732 134.0
XH1_k127_3548199_3 Small multi-drug export protein - - - 0.0005536 46.0
XH1_k127_3562150_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1391.0
XH1_k127_3562150_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1352.0
XH1_k127_3562150_10 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 2.004e-253 792.0
XH1_k127_3562150_11 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.579e-243 762.0
XH1_k127_3562150_12 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 9.168e-231 722.0
XH1_k127_3562150_13 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 5.666e-204 638.0
XH1_k127_3562150_14 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 5.611e-196 616.0
XH1_k127_3562150_15 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 583.0
XH1_k127_3562150_16 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 572.0
XH1_k127_3562150_17 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 562.0
XH1_k127_3562150_18 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 545.0
XH1_k127_3562150_19 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 490.0
XH1_k127_3562150_2 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.0 1314.0
XH1_k127_3562150_20 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 484.0
XH1_k127_3562150_21 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 469.0
XH1_k127_3562150_22 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 448.0
XH1_k127_3562150_23 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 438.0
XH1_k127_3562150_24 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 431.0
XH1_k127_3562150_25 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 407.0
XH1_k127_3562150_26 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 373.0
XH1_k127_3562150_27 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 372.0
XH1_k127_3562150_28 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 368.0
XH1_k127_3562150_29 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 369.0
XH1_k127_3562150_3 Tetratricopeptide repeat - - - 0.0 1288.0
XH1_k127_3562150_30 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 360.0
XH1_k127_3562150_31 Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor K00918 - 2.7.1.146,2.7.1.147 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 362.0
XH1_k127_3562150_32 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 327.0
XH1_k127_3562150_33 PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 319.0
XH1_k127_3562150_34 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 312.0
XH1_k127_3562150_35 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 302.0
XH1_k127_3562150_36 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005619 282.0
XH1_k127_3562150_37 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007863 264.0
XH1_k127_3562150_38 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002182 255.0
XH1_k127_3562150_39 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007996 254.0
XH1_k127_3562150_4 Belongs to the MCM family K10726 - - 0.0 1224.0
XH1_k127_3562150_40 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001131 233.0
XH1_k127_3562150_41 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000159 224.0
XH1_k127_3562150_42 Molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000001774 218.0
XH1_k127_3562150_43 B-block binding subunit of TFIIIC - - - 0.00000000000000000000000000000000000000000000000000000000001664 207.0
XH1_k127_3562150_44 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000000005464 179.0
XH1_k127_3562150_45 adenyl ribonucleotide binding - - - 0.0000000000000000000000000000000000000000000002652 173.0
XH1_k127_3562150_46 PFAM PEGA domain - - - 0.000000000000000000000000000000000000000000005438 177.0
XH1_k127_3562150_47 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000000000001415 164.0
XH1_k127_3562150_48 - - - - 0.0000000000000000000000000000000000000000001871 160.0
XH1_k127_3562150_49 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000000000000000000000616 149.0
XH1_k127_3562150_5 acid binding OB-fold tRNA helicase-type K07463 - - 0.0 1060.0
XH1_k127_3562150_50 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.0000000000000000000000000000000003545 134.0
XH1_k127_3562150_51 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000000000002201 130.0
XH1_k127_3562150_52 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000000007501 126.0
XH1_k127_3562150_53 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000002132 130.0
XH1_k127_3562150_54 - K00960 - 2.7.7.6 0.0000000000000000000000000000007419 121.0
XH1_k127_3562150_55 transcriptional K07729 - - 0.00000000000000000000000000005702 117.0
XH1_k127_3562150_56 - - - - 0.0000000000000000000000000002494 120.0
XH1_k127_3562150_57 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000002131 116.0
XH1_k127_3562150_58 - - - - 0.0000000000000000000000001738 106.0
XH1_k127_3562150_59 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000003924 98.0
XH1_k127_3562150_6 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 7.049e-301 938.0
XH1_k127_3562150_60 - - - - 0.00000000000000000008186 93.0
XH1_k127_3562150_61 - - - - 0.0000000000000000009225 92.0
XH1_k127_3562150_62 - - - - 0.0000000000000000142 85.0
XH1_k127_3562150_63 PFAM Tetratricopeptide repeat - - - 0.00000000000000001594 93.0
XH1_k127_3562150_64 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000002331 74.0
XH1_k127_3562150_7 Belongs to the glycosyl hydrolase 57 family - - - 1.288e-289 911.0
XH1_k127_3562150_8 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 1.656e-275 867.0
XH1_k127_3562150_9 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.92e-261 807.0
XH1_k127_3610404_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 604.0
XH1_k127_3610404_1 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002352 259.0
XH1_k127_3610404_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00005332 45.0
XH1_k127_3642237_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 4.822e-263 819.0
XH1_k127_3642237_1 PFAM type II secretion system protein E K07332 - - 1.661e-239 754.0
XH1_k127_3642237_10 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 391.0
XH1_k127_3642237_11 Membrane protein of unknown function DUF63 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 384.0
XH1_k127_3642237_12 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 370.0
XH1_k127_3642237_13 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 370.0
XH1_k127_3642237_14 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 352.0
XH1_k127_3642237_15 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 327.0
XH1_k127_3642237_16 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 322.0
XH1_k127_3642237_17 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 308.0
XH1_k127_3642237_18 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001249 273.0
XH1_k127_3642237_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004179 269.0
XH1_k127_3642237_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 8.113e-232 721.0
XH1_k127_3642237_20 Belongs to the UPF0179 family K09730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000209 243.0
XH1_k127_3642237_21 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000000000000000000000000000000000002086 232.0
XH1_k127_3642237_22 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000000000000000000000000000000000000003186 214.0
XH1_k127_3642237_23 Stage II sporulation protein M K06384 - - 0.000000000000000000000000000000000000000000000000000001759 197.0
XH1_k127_3642237_24 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000000000000001156 188.0
XH1_k127_3642237_25 Roadblock LC7 family protein K06945,K07131 - - 0.0000000000000000000000000000000000000000000001398 171.0
XH1_k127_3642237_26 metal-binding protein - - - 0.000000000000000000000000000007164 120.0
XH1_k127_3642237_27 PFAM Ribosomal protein S27E K02978 - - 0.000000000000000000000007162 105.0
XH1_k127_3642237_28 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000009891 98.0
XH1_k127_3642237_29 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000000000009363 87.0
XH1_k127_3642237_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 3.279e-206 647.0
XH1_k127_3642237_31 - - - - 0.0000000000007236 71.0
XH1_k127_3642237_4 PFAM peptidase M50 - - - 3.654e-200 631.0
XH1_k127_3642237_5 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 597.0
XH1_k127_3642237_6 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 554.0
XH1_k127_3642237_7 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 539.0
XH1_k127_3642237_8 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 538.0
XH1_k127_3642237_9 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 419.0
XH1_k127_3721063_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1737.0
XH1_k127_3721063_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.309e-306 944.0
XH1_k127_3721063_10 Major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 509.0
XH1_k127_3721063_11 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 499.0
XH1_k127_3721063_12 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 494.0
XH1_k127_3721063_13 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 470.0
XH1_k127_3721063_14 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 462.0
XH1_k127_3721063_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 477.0
XH1_k127_3721063_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 454.0
XH1_k127_3721063_17 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 452.0
XH1_k127_3721063_18 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008241 436.0
XH1_k127_3721063_19 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 404.0
XH1_k127_3721063_2 PFAM ABC-1 domain protein K03688 - - 1.04e-275 856.0
XH1_k127_3721063_20 PFAM GTP-binding protein HSR1-related K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 395.0
XH1_k127_3721063_21 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 391.0
XH1_k127_3721063_22 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 386.0
XH1_k127_3721063_23 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
XH1_k127_3721063_24 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 377.0
XH1_k127_3721063_25 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 371.0
XH1_k127_3721063_26 TIGRFAM F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 364.0
XH1_k127_3721063_27 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 365.0
XH1_k127_3721063_28 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 346.0
XH1_k127_3721063_29 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 336.0
XH1_k127_3721063_3 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 1.044e-264 818.0
XH1_k127_3721063_30 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 331.0
XH1_k127_3721063_31 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 317.0
XH1_k127_3721063_32 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 303.0
XH1_k127_3721063_33 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 292.0
XH1_k127_3721063_34 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 293.0
XH1_k127_3721063_35 Belongs to the UPF0305 family K07012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
XH1_k127_3721063_36 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002333 279.0
XH1_k127_3721063_37 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 271.0
XH1_k127_3721063_38 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000139 259.0
XH1_k127_3721063_39 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002452 276.0
XH1_k127_3721063_4 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.22e-261 815.0
XH1_k127_3721063_40 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008099 249.0
XH1_k127_3721063_41 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004378 244.0
XH1_k127_3721063_42 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000001126 235.0
XH1_k127_3721063_43 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001388 231.0
XH1_k127_3721063_44 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.00000000000000000000000000000000000000000000000000000000002282 207.0
XH1_k127_3721063_45 Zn-ribbon containing protein K07163 - - 0.0000000000000000000000000000000000000000000000000000000187 199.0
XH1_k127_3721063_46 - - - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
XH1_k127_3721063_47 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000003871 202.0
XH1_k127_3721063_48 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000001293 192.0
XH1_k127_3721063_49 - - - - 0.000000000000000000000000000000000000000000000000001707 188.0
XH1_k127_3721063_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.287e-232 722.0
XH1_k127_3721063_50 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000007344 156.0
XH1_k127_3721063_51 Uracil DNA glycosylase superfamily K03649 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097507,GO:0140097,GO:1901360 3.2.2.28 0.0000000000000000000000000000000000000174 149.0
XH1_k127_3721063_52 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000000000000005991 155.0
XH1_k127_3721063_53 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000002156 117.0
XH1_k127_3721063_54 negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment - - - 0.000000000000000000000000001461 116.0
XH1_k127_3721063_55 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000000000007774 99.0
XH1_k127_3721063_57 - - - - 0.000000001559 64.0
XH1_k127_3721063_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 7.922e-209 654.0
XH1_k127_3721063_7 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 4.726e-197 621.0
XH1_k127_3721063_8 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 553.0
XH1_k127_3721063_9 DNA methylase K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 548.0
XH1_k127_3731230_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 2.352e-217 683.0
XH1_k127_3731230_1 2Fe-2S iron-sulfur cluster binding domain - - - 3.556e-210 671.0
XH1_k127_3731230_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 544.0
XH1_k127_3731230_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 347.0
XH1_k127_3731230_4 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000002642 233.0
XH1_k127_3731230_5 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000003857 193.0
XH1_k127_3731230_6 - - - - 0.0000000000000000000000000000000000000401 149.0
XH1_k127_3731230_7 PFAM Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000000006008 128.0
XH1_k127_3736810_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0 1107.0
XH1_k127_3736810_1 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 4.976e-319 979.0
XH1_k127_3736810_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 519.0
XH1_k127_3736810_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000000000000000000000008742 141.0
XH1_k127_401226_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 1.653e-246 764.0
XH1_k127_401226_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 370.0
XH1_k127_401226_2 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 346.0
XH1_k127_401226_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000002929 255.0
XH1_k127_401226_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000002201 225.0
XH1_k127_401226_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000126 103.0
XH1_k127_401226_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000008844 51.0
XH1_k127_4212974_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.261e-225 703.0
XH1_k127_4212974_1 Ferrous iron transport B domain protein K04759 - - 1.662e-223 709.0
XH1_k127_4212974_10 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 452.0
XH1_k127_4212974_11 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 427.0
XH1_k127_4212974_12 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 417.0
XH1_k127_4212974_13 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 402.0
XH1_k127_4212974_14 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 384.0
XH1_k127_4212974_15 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 401.0
XH1_k127_4212974_16 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 359.0
XH1_k127_4212974_17 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 353.0
XH1_k127_4212974_18 toxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 311.0
XH1_k127_4212974_19 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 291.0
XH1_k127_4212974_2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 4.064e-218 689.0
XH1_k127_4212974_20 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001421 284.0
XH1_k127_4212974_21 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007521 246.0
XH1_k127_4212974_22 PFAM oxidoreductase nitrogenase, component 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001211 254.0
XH1_k127_4212974_23 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000003986 241.0
XH1_k127_4212974_24 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000004313 227.0
XH1_k127_4212974_25 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000184 216.0
XH1_k127_4212974_26 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000000000000008523 192.0
XH1_k127_4212974_27 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000001634 179.0
XH1_k127_4212974_28 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000000000000000000000002026 176.0
XH1_k127_4212974_29 iron dependent repressor K03709,K04758 - - 0.0000000000000000000000000000000000000000001205 168.0
XH1_k127_4212974_3 PFAM Cation K03498 - - 1.085e-216 681.0
XH1_k127_4212974_30 response regulator, receiver K03413,K07662,K07667 - - 0.000000000000000000000000000000000000000002228 161.0
XH1_k127_4212974_31 metallopeptidase activity - - - 0.00000000000000000000000000000000000000001397 169.0
XH1_k127_4212974_32 - - - - 0.0000000000000000000000000000000000000004017 153.0
XH1_k127_4212974_33 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000001419 149.0
XH1_k127_4212974_34 Phage plasmid primase, P4 K06919 - - 0.0000000000000000000000000000005482 131.0
XH1_k127_4212974_35 Domain of unknown function (DUF1894) - - - 0.000000000000000000001105 94.0
XH1_k127_4212974_36 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000007963 83.0
XH1_k127_4212974_37 Archaeal Type IV pilin, N-terminal - - - 0.0000000000000005279 89.0
XH1_k127_4212974_38 COG1520 FOG WD40-like repeat - - - 0.0000000002373 74.0
XH1_k127_4212974_4 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 8.875e-207 647.0
XH1_k127_4212974_5 PFAM beta-lactamase domain protein - - - 2.018e-197 621.0
XH1_k127_4212974_6 PFAM Radical SAM domain protein K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 520.0
XH1_k127_4212974_7 PFAM oxidoreductase nitrogenase, component 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 511.0
XH1_k127_4212974_8 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 466.0
XH1_k127_4212974_9 ADP-ribosylation factor family K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 469.0
XH1_k127_431017_0 PFAM formate nitrite transporter K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 460.0
XH1_k127_431017_1 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 370.0
XH1_k127_431017_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 374.0
XH1_k127_431017_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002077 259.0
XH1_k127_431017_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000001922 194.0
XH1_k127_431017_5 - - - - 0.0000000000000000000000000000008382 128.0
XH1_k127_4499642_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 4.266e-239 745.0
XH1_k127_4499642_1 PFAM phosphoesterase, RecJ domain protein K07463 - - 9.702e-226 705.0
XH1_k127_4499642_10 PFAM oxidoreductase domain protein K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 420.0
XH1_k127_4499642_11 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 372.0
XH1_k127_4499642_12 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 364.0
XH1_k127_4499642_13 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 355.0
XH1_k127_4499642_14 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 353.0
XH1_k127_4499642_15 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 317.0
XH1_k127_4499642_16 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005881 260.0
XH1_k127_4499642_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
XH1_k127_4499642_18 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000006731 242.0
XH1_k127_4499642_19 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000004426 215.0
XH1_k127_4499642_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 9.04e-214 671.0
XH1_k127_4499642_20 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000698 218.0
XH1_k127_4499642_21 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000000000000000000000000000004819 179.0
XH1_k127_4499642_22 - - - - 0.00000000000000000000000000000000000003488 148.0
XH1_k127_4499642_23 - - - - 0.0000000000000000000000000000001063 125.0
XH1_k127_4499642_25 PFAM PUA domain K07398 - - 0.000000000000000001805 93.0
XH1_k127_4499642_26 Archaeal Type IV pilin, N-terminal - - - 0.000000000000149 76.0
XH1_k127_4499642_27 - - - - 0.00000001316 64.0
XH1_k127_4499642_3 TIGRFAM small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 600.0
XH1_k127_4499642_4 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 545.0
XH1_k127_4499642_5 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 514.0
XH1_k127_4499642_6 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 481.0
XH1_k127_4499642_7 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 466.0
XH1_k127_4499642_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 460.0
XH1_k127_4499642_9 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 457.0
XH1_k127_4542136_0 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 479.0
XH1_k127_4542136_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 415.0
XH1_k127_4542136_2 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 388.0
XH1_k127_4542136_3 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 342.0
XH1_k127_4542136_4 PFAM major facilitator superfamily MFS_1 - - - 0.0000000007791 61.0
XH1_k127_4713895_0 Domain of unknown function (DUF814) - - - 1.498e-274 857.0
XH1_k127_4713895_1 in RNase L inhibitor, RLI K06174 - - 1.455e-237 737.0
XH1_k127_4713895_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005571 514.0
XH1_k127_4713895_3 PFAM Kelch repeat type 1 K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009856 267.0
XH1_k127_4713895_4 RNase L inhibitor, RLI - - - 0.000000000000000000000000000000000000000000007733 166.0
XH1_k127_4713895_5 PFAM PKD domain containing protein - - - 0.0000000000003439 78.0
XH1_k127_4713895_6 Putative metal-binding motif - - - 0.0000000000004948 81.0
XH1_k127_4713895_7 cell adhesion K03117,K12684,K19231 - - 0.00000000007568 72.0
XH1_k127_4713895_8 PFAM PKD domain containing protein - - - 0.0000008627 62.0
XH1_k127_4713895_9 - - - - 0.000745 51.0
XH1_k127_479867_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1693.0
XH1_k127_479867_1 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.0 1161.0
XH1_k127_479867_10 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 504.0
XH1_k127_479867_11 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 497.0
XH1_k127_479867_12 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 465.0
XH1_k127_479867_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 469.0
XH1_k127_479867_14 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 440.0
XH1_k127_479867_15 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 411.0
XH1_k127_479867_16 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 390.0
XH1_k127_479867_17 tRNAHis guanylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 346.0
XH1_k127_479867_18 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 321.0
XH1_k127_479867_19 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001665 282.0
XH1_k127_479867_2 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1045.0
XH1_k127_479867_20 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004661 253.0
XH1_k127_479867_21 Type I restriction-modification system methyltransferase subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000002515 235.0
XH1_k127_479867_22 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000003496 226.0
XH1_k127_479867_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000001476 223.0
XH1_k127_479867_24 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000000000000003164 198.0
XH1_k127_479867_25 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000000000000000002271 165.0
XH1_k127_479867_26 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000000000000000001626 152.0
XH1_k127_479867_27 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000002798 148.0
XH1_k127_479867_28 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.00000000000000000000000000000000003884 139.0
XH1_k127_479867_29 Phage plasmid primase, P4 K06919 - - 0.0000000000000000000000000004068 120.0
XH1_k127_479867_3 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147,K11085 - - 6.112e-289 902.0
XH1_k127_479867_30 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000000000000192 106.0
XH1_k127_479867_31 - - - - 0.00000000000000000007383 96.0
XH1_k127_479867_32 - - - - 0.00000000000001689 74.0
XH1_k127_479867_33 - - - - 0.0000000000008824 78.0
XH1_k127_479867_4 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 8.729e-281 874.0
XH1_k127_479867_5 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147,K11085 - - 1.968e-268 838.0
XH1_k127_479867_6 SMART Elongator protein 3 MiaB NifB - - - 2.157e-267 831.0
XH1_k127_479867_7 phosphoesterase RecJ domain protein - - - 2.921e-256 796.0
XH1_k127_479867_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 9.521e-212 661.0
XH1_k127_479867_9 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 568.0
XH1_k127_486906_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1393.0
XH1_k127_486906_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1090.0
XH1_k127_486906_10 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 576.0
XH1_k127_486906_11 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 566.0
XH1_k127_486906_12 PFAM Beta propeller domain K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 520.0
XH1_k127_486906_13 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 489.0
XH1_k127_486906_14 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 474.0
XH1_k127_486906_15 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 469.0
XH1_k127_486906_16 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 442.0
XH1_k127_486906_17 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 415.0
XH1_k127_486906_18 4-Hydroxyphenylpyruvate dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 358.0
XH1_k127_486906_19 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 348.0
XH1_k127_486906_2 PFAM Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 3.658e-298 926.0
XH1_k127_486906_20 V-type ATP synthase, subunit I K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 351.0
XH1_k127_486906_21 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 316.0
XH1_k127_486906_22 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 294.0
XH1_k127_486906_23 - K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000004292 237.0
XH1_k127_486906_24 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000000000000004184 224.0
XH1_k127_486906_25 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000004727 234.0
XH1_k127_486906_26 - - - - 0.000000000000000000000000000000000000000000000000000000445 196.0
XH1_k127_486906_27 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000001925 190.0
XH1_k127_486906_28 - - - - 0.00000000000000000000000000000000000000000000003015 176.0
XH1_k127_486906_29 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000001458 169.0
XH1_k127_486906_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 6.103e-246 771.0
XH1_k127_486906_30 ATP synthase subunit K K02124 - - 0.0000000000000000000000000000000000000000005761 162.0
XH1_k127_486906_32 - - - - 0.000000000000000000000000000000000001186 145.0
XH1_k127_486906_33 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000005402 151.0
XH1_k127_486906_34 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000009044 123.0
XH1_k127_486906_35 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000007452 111.0
XH1_k127_486906_36 ATP synthase subunit C K02124 - - 0.0000000000000000000001296 98.0
XH1_k127_486906_38 - - - - 0.000000000000002017 83.0
XH1_k127_486906_39 bacterial-type flagellum-dependent cell motility - - - 0.000000000000008682 87.0
XH1_k127_486906_4 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 1.232e-236 737.0
XH1_k127_486906_41 H subunit K02107 - - 0.0001872 48.0
XH1_k127_486906_42 Tetratricopeptide repeat - - - 0.0002547 45.0
XH1_k127_486906_5 V-type ATPase 116kDa subunit family K02123 - - 7.659e-225 713.0
XH1_k127_486906_6 TIGRFAM UbiD family - - - 2.744e-216 676.0
XH1_k127_486906_7 ATP synthase alpha/beta family, beta-barrel domain K02118 - - 5.24e-210 663.0
XH1_k127_486906_8 PBS lyase K22221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 592.0
XH1_k127_486906_9 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 602.0
XH1_k127_4893803_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 533.0
XH1_k127_4893803_1 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 478.0
XH1_k127_4893803_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 427.0
XH1_k127_4893803_3 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 368.0
XH1_k127_4893803_4 protein conserved in archaea - - - 0.00000000000000000000000000000000000005743 144.0
XH1_k127_4893803_6 - - - - 0.00004649 48.0
XH1_k127_5017560_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 601.0
XH1_k127_5017560_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 581.0
XH1_k127_5017560_10 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000004486 177.0
XH1_k127_5017560_2 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 505.0
XH1_k127_5017560_3 Glycosyltransferase 28 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 450.0
XH1_k127_5017560_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 406.0
XH1_k127_5017560_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 379.0
XH1_k127_5017560_6 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 347.0
XH1_k127_5017560_7 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 330.0
XH1_k127_5017560_8 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000003028 243.0
XH1_k127_5017560_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001407 237.0
XH1_k127_5226608_0 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 310.0
XH1_k127_5226608_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000144 275.0
XH1_k127_5226608_2 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000001944 185.0
XH1_k127_5226608_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000002008 181.0
XH1_k127_5226608_4 Zinc-ribbon containing domain - - - 0.000000000000000000000000000000000000000002257 155.0
XH1_k127_5226608_5 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.000000000000000003118 84.0
XH1_k127_5364357_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.564e-294 909.0
XH1_k127_5364357_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000003587 68.0
XH1_k127_5469497_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.311e-281 874.0
XH1_k127_5469497_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 1.007e-230 718.0
XH1_k127_5469497_10 - - - - 0.0000000000000000000000000002249 116.0
XH1_k127_5469497_11 - - - - 0.0000000000000000000000000002656 122.0
XH1_k127_5469497_12 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000004361 85.0
XH1_k127_5469497_14 Short repeat of unknown function (DUF308) - - - 0.0000002198 59.0
XH1_k127_5469497_15 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000003187 61.0
XH1_k127_5469497_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 1.522e-226 709.0
XH1_k127_5469497_3 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 436.0
XH1_k127_5469497_4 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 321.0
XH1_k127_5469497_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002129 282.0
XH1_k127_5469497_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000281 242.0
XH1_k127_5469497_7 DNA ligase D, 3-phosphoesterase domain - - - 0.0000000000000000000000000000000000000000000000007397 183.0
XH1_k127_5469497_8 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000003737 153.0
XH1_k127_5469497_9 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000005009 151.0
XH1_k127_5471808_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1062.0
XH1_k127_5471808_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1025.0
XH1_k127_5471808_10 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 3.76e-212 666.0
XH1_k127_5471808_11 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 2.629e-207 663.0
XH1_k127_5471808_12 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009598 531.0
XH1_k127_5471808_13 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 512.0
XH1_k127_5471808_14 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 500.0
XH1_k127_5471808_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 458.0
XH1_k127_5471808_16 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 422.0
XH1_k127_5471808_17 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 389.0
XH1_k127_5471808_18 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 367.0
XH1_k127_5471808_19 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 352.0
XH1_k127_5471808_2 type II secretion system protein K07333 - - 4.175e-271 847.0
XH1_k127_5471808_20 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 341.0
XH1_k127_5471808_21 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 329.0
XH1_k127_5471808_22 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 298.0
XH1_k127_5471808_23 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001541 276.0
XH1_k127_5471808_24 PFAM PUA domain containing protein K07575 - - 0.000000000000000000000000000000000000000000000000000000000000000000002163 241.0
XH1_k127_5471808_25 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000001662 240.0
XH1_k127_5471808_26 Pfam:DUF552 K09152 - - 0.0000000000000000000000000000000000000000000000000000000000000002549 221.0
XH1_k127_5471808_27 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000000000000000000000000002286 225.0
XH1_k127_5471808_28 ZPR1-related zinc finger protein K06874 - - 0.000000000000000000000000000000000000000000000000000000000000004767 221.0
XH1_k127_5471808_29 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000002216 179.0
XH1_k127_5471808_3 PFAM type II secretion system protein E K07332 - - 1.639e-268 836.0
XH1_k127_5471808_30 - - - - 0.00000000000000000000000000000000000000000000004694 175.0
XH1_k127_5471808_31 PIN domain of ribonuclease K07060 - - 0.00000000000000000000000000000000000000000000005639 173.0
XH1_k127_5471808_32 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.00000000000000000000000000000000000001372 147.0
XH1_k127_5471808_33 binds to the 23S rRNA K02922 - - 0.0000000000000000000000000000007518 121.0
XH1_k127_5471808_34 SigmaK-factor processing regulatory protein BofA K06317 - - 0.000000000000000000000000003035 112.0
XH1_k127_5471808_35 - - - - 0.0000000000000000000000001285 106.0
XH1_k127_5471808_36 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000006286 102.0
XH1_k127_5471808_37 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000007006 103.0
XH1_k127_5471808_39 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000002207 96.0
XH1_k127_5471808_4 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.785e-266 828.0
XH1_k127_5471808_40 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000005472 87.0
XH1_k127_5471808_41 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000008623 76.0
XH1_k127_5471808_5 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 2.93e-263 824.0
XH1_k127_5471808_6 DEAD DEAH box helicase K03724 - - 1.136e-255 807.0
XH1_k127_5471808_7 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 7.569e-252 783.0
XH1_k127_5471808_8 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.44e-245 766.0
XH1_k127_5471808_9 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.081e-236 742.0
XH1_k127_5682747_0 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 399.0
XH1_k127_5682747_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008712 238.0
XH1_k127_5682747_2 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000006281 231.0
XH1_k127_5696104_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1676.0
XH1_k127_5696104_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1591.0
XH1_k127_5696104_10 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001217 282.0
XH1_k127_5696104_11 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003728 258.0
XH1_k127_5696104_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004248 238.0
XH1_k127_5696104_13 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000000000000000000000000000000000000001385 201.0
XH1_k127_5696104_14 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000002917 198.0
XH1_k127_5696104_15 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000000000000000000000000000000001257 169.0
XH1_k127_5696104_16 Roadblock LC7 family protein K06945,K07131 - - 0.00000000000000000000000000000000000000000009652 163.0
XH1_k127_5696104_17 - - - - 0.00000000000000000000000000000000000007519 144.0
XH1_k127_5696104_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000000000000000005137 138.0
XH1_k127_5696104_19 - - - - 0.00000000000000001095 87.0
XH1_k127_5696104_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0 1105.0
XH1_k127_5696104_20 - - - - 0.00000000000002867 76.0
XH1_k127_5696104_21 histone H2A K63-linked ubiquitination - - - 0.00000007399 59.0
XH1_k127_5696104_3 PFAM PilT protein domain protein K06865 - - 0.0 1010.0
XH1_k127_5696104_4 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 2.134e-320 983.0
XH1_k127_5696104_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 5.521e-220 686.0
XH1_k127_5696104_6 TIGRFAM cell division ATPase MinD K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 426.0
XH1_k127_5696104_7 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 405.0
XH1_k127_5696104_8 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 376.0
XH1_k127_5696104_9 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 289.0
XH1_k127_5844310_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 2.267e-206 646.0
XH1_k127_5844310_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000005739 246.0
XH1_k127_5844310_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000141 167.0
XH1_k127_5993163_0 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 453.0
XH1_k127_5993163_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 342.0
XH1_k127_5993163_2 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000003578 158.0
XH1_k127_6075363_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 4.326e-218 691.0
XH1_k127_6075363_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 364.0
XH1_k127_6075363_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 336.0
XH1_k127_6075363_3 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000007649 244.0
XH1_k127_6075363_4 Transcriptional regulator K07108 - - 0.0000000000000000000000000000000000009765 145.0
XH1_k127_6075363_5 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000000000000000003153 130.0
XH1_k127_6075363_6 transcriptional regulators K03724 - - 0.0000000000000000000000000000146 119.0
XH1_k127_6075363_7 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000000000000002581 111.0
XH1_k127_6075363_8 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000001846 112.0
XH1_k127_6075363_9 nucleic acid binding OB-fold tRNA helicase-type - - - 0.00000000000000000000000244 107.0
XH1_k127_6266558_0 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 528.0
XH1_k127_6266558_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 409.0
XH1_k127_6266558_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 394.0
XH1_k127_6266558_3 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 364.0
XH1_k127_6266558_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 343.0
XH1_k127_6266558_5 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001633 263.0
XH1_k127_6266558_6 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000000000000000000000004213 224.0
XH1_k127_6266558_7 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000002938 221.0
XH1_k127_6266558_8 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.0000000000604 73.0
XH1_k127_6266558_9 PFAM PKD domain containing protein - - - 0.0002365 53.0
XH1_k127_6361434_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1286.0
XH1_k127_6361434_1 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 2.734e-278 860.0
XH1_k127_6361434_10 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 351.0
XH1_k127_6361434_11 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 343.0
XH1_k127_6361434_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 290.0
XH1_k127_6361434_13 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002459 287.0
XH1_k127_6361434_14 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003865 280.0
XH1_k127_6361434_15 COG1202 Superfamily II helicase, archaea-specific - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001754 249.0
XH1_k127_6361434_16 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000135 246.0
XH1_k127_6361434_17 Fe-S-cluster oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000004586 203.0
XH1_k127_6361434_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07652 - 2.7.13.3 0.000000000000000000000000000000000000000000000000018 194.0
XH1_k127_6361434_19 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000121 171.0
XH1_k127_6361434_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 1.172e-217 679.0
XH1_k127_6361434_20 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000005802 162.0
XH1_k127_6361434_21 PFAM PEGA domain - - - 0.00000000000000000000000000000000002519 151.0
XH1_k127_6361434_22 Thaumatin family - GO:0008150,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009723,GO:0009725,GO:0010033,GO:0042221,GO:0043207,GO:0050896,GO:0051704,GO:0051707 - 0.000000000000000000000000000000152 138.0
XH1_k127_6361434_23 PDGLE domain K02009 - - 0.000000000000000000000002239 112.0
XH1_k127_6361434_24 - K06868 - 2.5.1.73 0.000000000000000002806 87.0
XH1_k127_6361434_25 BON domain - - - 0.0000000003186 66.0
XH1_k127_6361434_26 Beta-L-arabinofuranosidase, GH127 - - - 0.000000001141 70.0
XH1_k127_6361434_27 Stigma-specific protein, Stig1 - GO:0000003,GO:0003006,GO:0005575,GO:0005576,GO:0007275,GO:0008150,GO:0009790,GO:0009791,GO:0009793,GO:0010154,GO:0022414,GO:0032501,GO:0032502,GO:0042335,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0061458 - 0.0000004569 61.0
XH1_k127_6361434_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 7.605e-214 674.0
XH1_k127_6361434_4 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 8.754e-210 657.0
XH1_k127_6361434_5 Polyphosphate kinase 2 (PPK2) - - - 6.349e-200 634.0
XH1_k127_6361434_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 507.0
XH1_k127_6361434_7 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 462.0
XH1_k127_6361434_8 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 427.0
XH1_k127_6361434_9 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 424.0
XH1_k127_6510896_0 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 606.0
XH1_k127_6510896_1 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 578.0
XH1_k127_6510896_10 Domain of unknown function (DUF3821) - - - 0.000000000000000000000000000000000000000000000000000116 214.0
XH1_k127_6510896_11 - - - - 0.0000000000000000000000000000000000000000002608 159.0
XH1_k127_6510896_12 metallopeptidase activity - - - 0.0000000000000000000000000002895 134.0
XH1_k127_6510896_15 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.0000000000000002072 83.0
XH1_k127_6510896_16 WD-40 repeat protein - - - 0.0000000000002156 83.0
XH1_k127_6510896_17 - - - - 0.0000000000009754 74.0
XH1_k127_6510896_18 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000267 57.0
XH1_k127_6510896_19 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.0002316 45.0
XH1_k127_6510896_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 477.0
XH1_k127_6510896_3 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 446.0
XH1_k127_6510896_4 PFAM amino acid-binding ACT domain protein K06862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 372.0
XH1_k127_6510896_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 312.0
XH1_k127_6510896_6 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000001039 266.0
XH1_k127_6510896_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001837 249.0
XH1_k127_6510896_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002843 243.0
XH1_k127_6510896_9 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000008497 224.0
XH1_k127_679104_0 PFAM major facilitator superfamily MFS_1 - - - 1.314e-204 647.0
XH1_k127_679104_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 604.0
XH1_k127_679104_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 491.0
XH1_k127_679104_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 442.0
XH1_k127_679104_4 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 401.0
XH1_k127_679104_5 Oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005816 273.0
XH1_k127_679104_6 Fumarase C-terminus K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001967 275.0
XH1_k127_679104_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000005863 190.0
XH1_k127_6887074_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.0 1065.0
XH1_k127_6887074_1 PFAM Radical SAM domain protein K06871 - - 2.187e-196 617.0
XH1_k127_6887074_10 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000002439 204.0
XH1_k127_6887074_11 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.000000000000000000000000000000000000000001198 156.0
XH1_k127_6887074_12 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.000000000000000000000000000000000000000006433 157.0
XH1_k127_6887074_13 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000004633 86.0
XH1_k127_6887074_14 Belongs to the UPF0251 family K06933 - - 0.00000001436 58.0
XH1_k127_6887074_15 - - - - 0.00000214 54.0
XH1_k127_6887074_2 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00581 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 555.0
XH1_k127_6887074_3 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 506.0
XH1_k127_6887074_4 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 458.0
XH1_k127_6887074_5 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 449.0
XH1_k127_6887074_6 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 451.0
XH1_k127_6887074_7 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 394.0
XH1_k127_6887074_8 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 379.0
XH1_k127_6887074_9 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006207 262.0
XH1_k127_6904376_0 PFAM NAD(P) transhydrogenase, beta subunit K00325 - 1.6.1.2 6.979e-241 753.0
XH1_k127_6904376_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 1.593e-231 724.0
XH1_k127_6904376_2 PFAM PUA domain containing protein K07557 - 2.6.1.97 5.984e-230 723.0
XH1_k127_6904376_3 PFAM alanine dehydrogenase PNT domain protein K00259,K00324 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1,1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 586.0
XH1_k127_6904376_4 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000002573 177.0
XH1_k127_7063192_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.224e-221 692.0
XH1_k127_7063192_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 302.0
XH1_k127_7063192_2 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.3.3.14 0.00000000000000004007 83.0
XH1_k127_7114091_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 9.595e-246 771.0
XH1_k127_7114091_1 PFAM Radical SAM domain protein K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 564.0
XH1_k127_7114091_2 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 540.0
XH1_k127_7114091_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 329.0
XH1_k127_7114091_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000002934 231.0
XH1_k127_7114091_5 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000001188 168.0
XH1_k127_7299851_0 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008364 418.0
XH1_k127_7299851_1 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 313.0
XH1_k127_7299851_2 Pas domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 317.0
XH1_k127_737648_0 2Fe-2S iron-sulfur cluster binding domain - - - 1.122e-207 663.0
XH1_k127_737648_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 415.0
XH1_k127_737648_2 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000002084 67.0
XH1_k127_748386_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 9.585e-303 941.0
XH1_k127_748386_1 PFAM glutamate--cysteine ligase, GCS2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 475.0
XH1_k127_748386_2 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 401.0
XH1_k127_7718775_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1154.0
XH1_k127_7718775_1 PFAM type II secretion system protein E K07332 - - 0.0 1062.0
XH1_k127_7718775_10 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 552.0
XH1_k127_7718775_11 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 518.0
XH1_k127_7718775_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 508.0
XH1_k127_7718775_13 phosphohydrolase (DHH superfamily) K07097 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 490.0
XH1_k127_7718775_14 Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 471.0
XH1_k127_7718775_15 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 457.0
XH1_k127_7718775_16 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 461.0
XH1_k127_7718775_17 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 443.0
XH1_k127_7718775_18 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 438.0
XH1_k127_7718775_19 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 397.0
XH1_k127_7718775_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.034e-280 866.0
XH1_k127_7718775_20 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 397.0
XH1_k127_7718775_21 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
XH1_k127_7718775_22 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 373.0
XH1_k127_7718775_23 PFAM ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 369.0
XH1_k127_7718775_24 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 348.0
XH1_k127_7718775_25 Type II secretion system (T2SS), protein F K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 349.0
XH1_k127_7718775_26 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 354.0
XH1_k127_7718775_27 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 331.0
XH1_k127_7718775_28 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 331.0
XH1_k127_7718775_29 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 309.0
XH1_k127_7718775_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 4.53e-247 766.0
XH1_k127_7718775_30 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 303.0
XH1_k127_7718775_31 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 301.0
XH1_k127_7718775_32 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 291.0
XH1_k127_7718775_33 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 288.0
XH1_k127_7718775_34 archaeal Zn-finger protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006413 278.0
XH1_k127_7718775_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006456 280.0
XH1_k127_7718775_36 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002895 286.0
XH1_k127_7718775_37 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001557 269.0
XH1_k127_7718775_38 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000000000001407 243.0
XH1_k127_7718775_39 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000002529 243.0
XH1_k127_7718775_4 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.491e-220 689.0
XH1_k127_7718775_40 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
XH1_k127_7718775_41 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000000006929 231.0
XH1_k127_7718775_42 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000001701 219.0
XH1_k127_7718775_43 PFAM methyltransferase small K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000004168 218.0
XH1_k127_7718775_44 - - - - 0.0000000000000000000000000000000000000000000000000000000002005 219.0
XH1_k127_7718775_45 Belongs to the SUI1 family K03113 - - 0.0000000000000000000000000000000000000000000000000000000005163 202.0
XH1_k127_7718775_46 - - - - 0.00000000000000000000000000000000000000000000000000000001187 207.0
XH1_k127_7718775_47 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000000000000000000000000000000000000000006489 191.0
XH1_k127_7718775_48 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000000000005293 190.0
XH1_k127_7718775_49 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000000000000000000000000000004557 184.0
XH1_k127_7718775_5 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 7.918e-220 685.0
XH1_k127_7718775_50 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000000000000000000000000003488 181.0
XH1_k127_7718775_51 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0000000000000000000000000000000000000000000000001883 182.0
XH1_k127_7718775_52 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000000000000000000000000000000042 177.0
XH1_k127_7718775_53 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000000000000000000000000000000000002716 172.0
XH1_k127_7718775_54 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000003747 176.0
XH1_k127_7718775_55 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000000000000000000000000000000004297 155.0
XH1_k127_7718775_56 binds to the 23S rRNA K02921 - - 0.00000000000000000000000000000000000000001985 154.0
XH1_k127_7718775_57 - - - - 0.0000000000000000000000000000000000000002709 152.0
XH1_k127_7718775_58 - - - - 0.0000000000000000000000000000000000000003257 156.0
XH1_k127_7718775_59 - - - - 0.0000000000000000000000000000000000000012 150.0
XH1_k127_7718775_6 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.887e-215 680.0
XH1_k127_7718775_60 Roadblock LC7 - - - 0.000000000000000000000000000000000001277 140.0
XH1_k127_7718775_61 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000000000000371 125.0
XH1_k127_7718775_62 - - - - 0.000000000000000000000000000002771 121.0
XH1_k127_7718775_63 Armadillo/beta-catenin-like repeats - - - 0.000000000000000000000000374 110.0
XH1_k127_7718775_64 CRS1_YhbY K07574 - - 0.000000000000000000000004033 103.0
XH1_k127_7718775_65 PFAM Ribosomal LX protein K02944 - - 0.00000000000000000000001104 101.0
XH1_k127_7718775_66 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003541 98.0
XH1_k127_7718775_67 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000005779 100.0
XH1_k127_7718775_68 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000000006196 94.0
XH1_k127_7718775_69 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000001231 100.0
XH1_k127_7718775_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 5.08e-200 636.0
XH1_k127_7718775_70 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000001614 94.0
XH1_k127_7718775_71 - - - - 0.00000000000002527 73.0
XH1_k127_7718775_72 exodeoxyribonuclease VII activity K03602 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008855,GO:0009056,GO:0009057,GO:0009318,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575,GO:1902494 3.1.11.6 0.0001764 46.0
XH1_k127_7718775_8 CBS domain containing protein - - - 3.425e-195 617.0
XH1_k127_7718775_9 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 1.247e-194 614.0
XH1_k127_7739840_0 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 370.0
XH1_k127_7739840_1 DGC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002294 259.0
XH1_k127_7739840_2 - - - - 0.00000000000000000000000000000000000000000000000000000001578 200.0
XH1_k127_7739840_3 PFAM Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000000000622 186.0
XH1_k127_7739840_4 DGC domain - - - 0.00000000000000000000000000000000006097 136.0
XH1_k127_7739840_5 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000000000000000000002567 124.0
XH1_k127_7739840_6 protein conserved in archaea - - - 0.00000000000000000000001965 113.0
XH1_k127_7739840_7 Domain of unknown function - - - 0.000009475 49.0
XH1_k127_7876275_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1820.0
XH1_k127_7876275_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1308.0
XH1_k127_7876275_10 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006914 582.0
XH1_k127_7876275_11 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 563.0
XH1_k127_7876275_12 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 537.0
XH1_k127_7876275_13 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 530.0
XH1_k127_7876275_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 532.0
XH1_k127_7876275_15 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 526.0
XH1_k127_7876275_16 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 509.0
XH1_k127_7876275_17 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 459.0
XH1_k127_7876275_18 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 437.0
XH1_k127_7876275_19 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 421.0
XH1_k127_7876275_2 DEAD DEAH box helicase domain protein K10896 - - 0.0 1187.0
XH1_k127_7876275_20 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 423.0
XH1_k127_7876275_21 Metallo-beta-lactamase superfamily K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 426.0
XH1_k127_7876275_22 ATP-grasp domain K06914 - 6.3.4.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 409.0
XH1_k127_7876275_23 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 391.0
XH1_k127_7876275_24 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 376.0
XH1_k127_7876275_25 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 345.0
XH1_k127_7876275_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 345.0
XH1_k127_7876275_27 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 346.0
XH1_k127_7876275_28 Alpha beta hydrolase K01066,K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
XH1_k127_7876275_29 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 343.0
XH1_k127_7876275_3 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 1.261e-314 973.0
XH1_k127_7876275_30 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 343.0
XH1_k127_7876275_31 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 340.0
XH1_k127_7876275_32 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 337.0
XH1_k127_7876275_33 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 329.0
XH1_k127_7876275_34 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 325.0
XH1_k127_7876275_35 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 329.0
XH1_k127_7876275_36 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 308.0
XH1_k127_7876275_37 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 304.0
XH1_k127_7876275_38 COG2406 Protein distantly related to bacterial ferritins K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 298.0
XH1_k127_7876275_39 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 296.0
XH1_k127_7876275_4 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 6.608e-257 808.0
XH1_k127_7876275_40 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008792 280.0
XH1_k127_7876275_41 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001105 289.0
XH1_k127_7876275_42 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005522 270.0
XH1_k127_7876275_43 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000297 265.0
XH1_k127_7876275_44 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003188 269.0
XH1_k127_7876275_45 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 262.0
XH1_k127_7876275_46 PFAM transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004145 262.0
XH1_k127_7876275_47 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002511 254.0
XH1_k127_7876275_48 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000001111 241.0
XH1_k127_7876275_49 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001173 244.0
XH1_k127_7876275_5 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 2.386e-211 661.0
XH1_k127_7876275_50 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000009191 240.0
XH1_k127_7876275_51 Pas domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001815 247.0
XH1_k127_7876275_52 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000002503 235.0
XH1_k127_7876275_53 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001588 233.0
XH1_k127_7876275_54 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004855 230.0
XH1_k127_7876275_55 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000104 220.0
XH1_k127_7876275_56 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000008201 214.0
XH1_k127_7876275_57 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000001494 235.0
XH1_k127_7876275_58 hydrolase K04794 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000005509 209.0
XH1_k127_7876275_59 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000000000000000000000000000000001919 200.0
XH1_k127_7876275_6 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.16e-205 660.0
XH1_k127_7876275_60 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
XH1_k127_7876275_61 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000007958 191.0
XH1_k127_7876275_62 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000000000000000000000000000000000000000009753 177.0
XH1_k127_7876275_63 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000001244 176.0
XH1_k127_7876275_64 Regulatory protein MarR - - - 0.00000000000000000000000000000000000000000002187 165.0
XH1_k127_7876275_65 - - - - 0.00000000000000000000000000000000000000000006424 162.0
XH1_k127_7876275_66 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000000000000000000001075 162.0
XH1_k127_7876275_67 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000006802 156.0
XH1_k127_7876275_68 - - - - 0.000000000000000000000000000000000001066 143.0
XH1_k127_7876275_69 PFAM Glutaredoxin - - - 0.000000000000000000000000000000003427 130.0
XH1_k127_7876275_7 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 1.052e-195 617.0
XH1_k127_7876275_70 ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000003258 138.0
XH1_k127_7876275_71 PFAM response regulator receiver - - - 0.00000000000000000000000000004098 121.0
XH1_k127_7876275_72 Archaeal Type IV pilin, N-terminal - - - 0.000000000000000000000000005956 115.0
XH1_k127_7876275_73 - - - - 0.00000000000000000001993 94.0
XH1_k127_7876275_74 - - - - 0.0000000000000000001297 89.0
XH1_k127_7876275_75 PBS lyase HEAT-like repeat - - - 0.000000000000000001993 90.0
XH1_k127_7876275_76 - - - - 0.000000000000000008964 86.0
XH1_k127_7876275_77 CBS domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000001008 91.0
XH1_k127_7876275_79 - - - - 0.000000000000003436 78.0
XH1_k127_7876275_8 PFAM aldo keto reductase K07079 - - 3.578e-195 617.0
XH1_k127_7876275_81 META domain - - - 0.00000000004359 70.0
XH1_k127_7876275_82 - K06193 - - 0.00000000004596 69.0
XH1_k127_7876275_83 serine-type endopeptidase activity K00505,K01342,K02035 - 1.14.18.1,3.4.21.62 0.000000001023 70.0
XH1_k127_7876275_84 TIR domain - - - 0.00000000216 66.0
XH1_k127_7876275_86 Protein of unknown function (DUF3006) - - - 0.00000004277 57.0
XH1_k127_7876275_87 Short repeat of unknown function (DUF308) - - - 0.000007085 55.0
XH1_k127_7876275_9 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 615.0
XH1_k127_8003181_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.141e-204 644.0
XH1_k127_8003181_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 338.0
XH1_k127_8003181_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000007026 175.0
XH1_k127_8003181_3 ATP synthase subunit K K02124 - - 0.0000000000000000000000000000000000000000000006439 170.0
XH1_k127_8003181_4 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000026 152.0
XH1_k127_8003181_5 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.00000000000000008761 80.0
XH1_k127_8068010_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.098e-306 942.0
XH1_k127_8068010_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.915e-279 868.0
XH1_k127_8068010_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 552.0
XH1_k127_8068010_11 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 541.0
XH1_k127_8068010_12 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 534.0
XH1_k127_8068010_13 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 522.0
XH1_k127_8068010_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 516.0
XH1_k127_8068010_15 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 493.0
XH1_k127_8068010_16 signal transduction protein with CBS domains K07744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 469.0
XH1_k127_8068010_17 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 453.0
XH1_k127_8068010_18 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 422.0
XH1_k127_8068010_19 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 376.0
XH1_k127_8068010_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 5.753e-223 696.0
XH1_k127_8068010_20 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 359.0
XH1_k127_8068010_21 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 357.0
XH1_k127_8068010_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 332.0
XH1_k127_8068010_23 PFAM Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 332.0
XH1_k127_8068010_24 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 320.0
XH1_k127_8068010_25 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 314.0
XH1_k127_8068010_26 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006603 248.0
XH1_k127_8068010_27 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000002918 256.0
XH1_k127_8068010_28 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000006588 241.0
XH1_k127_8068010_29 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000008792 233.0
XH1_k127_8068010_3 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 8.236e-223 697.0
XH1_k127_8068010_30 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000001432 199.0
XH1_k127_8068010_31 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000001904 198.0
XH1_k127_8068010_32 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000004799 183.0
XH1_k127_8068010_33 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000002502 169.0
XH1_k127_8068010_34 TfuA-like protein - - - 0.000000000000000000000000000000000000000000248 166.0
XH1_k127_8068010_35 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000000000002239 149.0
XH1_k127_8068010_36 - - - - 0.0000000000000000000000000000000000004065 143.0
XH1_k127_8068010_37 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000001573 138.0
XH1_k127_8068010_38 - - - - 0.000000000000000000000000000004527 121.0
XH1_k127_8068010_39 transcription factor (CBF NF-Y) - - - 0.000000000000000000000000003183 112.0
XH1_k127_8068010_4 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 6.986e-215 672.0
XH1_k127_8068010_40 PFAM Uncharacterised conserved protein UCP006577 - - - 0.00000000000000000009013 91.0
XH1_k127_8068010_41 - - - - 0.0000000000000000005563 96.0
XH1_k127_8068010_42 - - - - 0.000000000000000007103 85.0
XH1_k127_8068010_43 PFAM TPR repeat-containing protein - - - 0.000000000003535 76.0
XH1_k127_8068010_44 Anaphase-promoting complex, cyclosome, subunit 3 K03350 GO:0000070,GO:0000151,GO:0000152,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0022402,GO:0030071,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051276,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0090068,GO:0097159,GO:0098813,GO:0140014,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252 - 0.00004561 56.0
XH1_k127_8068010_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 2.952e-210 657.0
XH1_k127_8068010_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 9.867e-210 660.0
XH1_k127_8068010_7 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 2.759e-197 621.0
XH1_k127_8068010_8 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 589.0
XH1_k127_8068010_9 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 580.0
XH1_k127_8116607_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1115.0
XH1_k127_8116607_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 6.191e-258 797.0
XH1_k127_8183266_0 PFAM ABC transporter K00400 - - 1.132e-288 893.0
XH1_k127_8183266_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.253e-276 862.0
XH1_k127_8183266_10 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 587.0
XH1_k127_8183266_11 methanogenesis marker protein 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 501.0
XH1_k127_8183266_12 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008447 479.0
XH1_k127_8183266_13 PhoU domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 443.0
XH1_k127_8183266_14 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 437.0
XH1_k127_8183266_15 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 401.0
XH1_k127_8183266_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 398.0
XH1_k127_8183266_17 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 377.0
XH1_k127_8183266_18 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 364.0
XH1_k127_8183266_19 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 337.0
XH1_k127_8183266_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 3.337e-242 756.0
XH1_k127_8183266_20 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 311.0
XH1_k127_8183266_21 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 310.0
XH1_k127_8183266_22 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 298.0
XH1_k127_8183266_23 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 310.0
XH1_k127_8183266_24 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006574 267.0
XH1_k127_8183266_25 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006334 257.0
XH1_k127_8183266_26 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004869 255.0
XH1_k127_8183266_27 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003491 252.0
XH1_k127_8183266_28 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000000000000000000000000000000000000000001535 210.0
XH1_k127_8183266_29 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000002074 214.0
XH1_k127_8183266_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 5.423e-237 737.0
XH1_k127_8183266_30 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.00000000000000000000000000000000000000000000000000000000009073 209.0
XH1_k127_8183266_31 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000008856 207.0
XH1_k127_8183266_32 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000000000000000000000000002059 195.0
XH1_k127_8183266_33 Hydrogenase maturation protease K08315 - 3.4.23.51 0.00000000000000000000000000000000000000000008571 164.0
XH1_k127_8183266_34 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000000000002233 154.0
XH1_k127_8183266_35 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000000000000000001151 150.0
XH1_k127_8183266_36 - - - - 0.00000000000000000000000000000000000001151 147.0
XH1_k127_8183266_37 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000000008365 139.0
XH1_k127_8183266_38 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.00000000000000000000000000000000003083 139.0
XH1_k127_8183266_39 - - - - 0.00000000000000000000000000000000006425 138.0
XH1_k127_8183266_4 Proton-conducting membrane transporter K05568 - - 2.034e-224 706.0
XH1_k127_8183266_40 Multisubunit Na H antiporter, MnhF subunit K05570 - - 0.0000000000000000000000001449 108.0
XH1_k127_8183266_41 Domain of unknown function (DUF4040) - - - 0.000000000000000000000009178 102.0
XH1_k127_8183266_42 Membrane bound hydrogenase - - - 0.000000000000000004216 87.0
XH1_k127_8183266_43 - - - - 0.00000000000000003858 86.0
XH1_k127_8183266_46 - - - - 0.0001037 48.0
XH1_k127_8183266_5 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 2.197e-221 692.0
XH1_k127_8183266_6 Belongs to the UPF0288 family - - - 7.517e-214 677.0
XH1_k127_8183266_7 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 1.018e-209 661.0
XH1_k127_8183266_8 ABC-type transport system involved in lipoprotein release permease component K02004 - - 1.11e-200 636.0
XH1_k127_8183266_9 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 593.0
XH1_k127_8238069_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1996.0
XH1_k127_8238069_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1516.0
XH1_k127_8238069_10 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.522e-270 842.0
XH1_k127_8238069_100 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000008577 247.0
XH1_k127_8238069_101 toxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006186 245.0
XH1_k127_8238069_102 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008203 243.0
XH1_k127_8238069_103 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000000000000001179 237.0
XH1_k127_8238069_104 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000684 226.0
XH1_k127_8238069_105 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002715 230.0
XH1_k127_8238069_106 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000002654 222.0
XH1_k127_8238069_107 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.000000000000000000000000000000000000000000000000000000000000001422 224.0
XH1_k127_8238069_108 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000001381 218.0
XH1_k127_8238069_109 - - - - 0.000000000000000000000000000000000000000000000000000000000002045 214.0
XH1_k127_8238069_11 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.167e-263 821.0
XH1_k127_8238069_110 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000001281 210.0
XH1_k127_8238069_111 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000003258 207.0
XH1_k127_8238069_112 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000005815 206.0
XH1_k127_8238069_113 - - - - 0.000000000000000000000000000000000000000000000000000000001911 207.0
XH1_k127_8238069_114 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000000000000000005516 200.0
XH1_k127_8238069_115 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000001393 201.0
XH1_k127_8238069_116 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000000000000000000000000000000000001496 194.0
XH1_k127_8238069_117 - - - - 0.00000000000000000000000000000000000000000000000000001182 193.0
XH1_k127_8238069_118 - - - - 0.0000000000000000000000000000000000000000000000000005083 192.0
XH1_k127_8238069_119 - - - - 0.000000000000000000000000000000000000000000000000003526 197.0
XH1_k127_8238069_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.425e-261 809.0
XH1_k127_8238069_120 - - - - 0.000000000000000000000000000000000000000000000000008947 183.0
XH1_k127_8238069_121 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000001529 200.0
XH1_k127_8238069_122 coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.0000000000000000000000000000000000000000000000001463 182.0
XH1_k127_8238069_123 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000003795 182.0
XH1_k127_8238069_124 - - - - 0.000000000000000000000000000000000000000000000009136 183.0
XH1_k127_8238069_125 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000002886 173.0
XH1_k127_8238069_126 Flavodoxin - - - 0.00000000000000000000000000000000000000000000003067 175.0
XH1_k127_8238069_127 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000001758 180.0
XH1_k127_8238069_128 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000215 176.0
XH1_k127_8238069_129 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000000000000000000000000000000004833 168.0
XH1_k127_8238069_13 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 5.238e-249 771.0
XH1_k127_8238069_130 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000006974 167.0
XH1_k127_8238069_131 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.000000000000000000000000000000000000000000007414 166.0
XH1_k127_8238069_132 PFAM Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000001061 164.0
XH1_k127_8238069_133 conserved protein (DUF2075) K09384 - - 0.0000000000000000000000000000000000000000002113 165.0
XH1_k127_8238069_134 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000002336 163.0
XH1_k127_8238069_135 - - - - 0.0000000000000000000000000000000000000000002839 162.0
XH1_k127_8238069_136 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000000000000000000000002179 158.0
XH1_k127_8238069_137 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000000000000002349 160.0
XH1_k127_8238069_138 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000003548 152.0
XH1_k127_8238069_139 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171,K00188 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000132 145.0
XH1_k127_8238069_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 2.03e-247 772.0
XH1_k127_8238069_140 - - - - 0.00000000000000000000000000000000000007927 159.0
XH1_k127_8238069_141 Small multi-drug export protein - - - 0.0000000000000000000000000000000000001869 154.0
XH1_k127_8238069_142 - K00960 - 2.7.7.6 0.00000000000000000000000000000000004732 134.0
XH1_k127_8238069_143 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000007299 136.0
XH1_k127_8238069_144 - - - - 0.0000000000000000000000000000000003063 135.0
XH1_k127_8238069_145 - - - - 0.0000000000000000000000000000000003131 131.0
XH1_k127_8238069_146 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000000000000000004524 132.0
XH1_k127_8238069_147 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000000000005627 133.0
XH1_k127_8238069_148 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.0000000000000000000000000000000142 128.0
XH1_k127_8238069_149 PFAM metallophosphoesterase - - - 0.00000000000000000000000000004497 129.0
XH1_k127_8238069_15 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 2.279e-226 705.0
XH1_k127_8238069_150 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000005341 123.0
XH1_k127_8238069_151 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000000704 115.0
XH1_k127_8238069_152 - - - - 0.0000000000000000000000000005464 123.0
XH1_k127_8238069_153 - - - - 0.000000000000000000000000002195 120.0
XH1_k127_8238069_154 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000000000004045 114.0
XH1_k127_8238069_155 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000000000000003826 109.0
XH1_k127_8238069_156 Domain of unknown function (DUF333) K09712 - - 0.0000000000000000000000001104 109.0
XH1_k127_8238069_157 DGC domain - - - 0.000000000000000000000001013 108.0
XH1_k127_8238069_158 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000000000002796 102.0
XH1_k127_8238069_159 DGC domain - - - 0.000000000000000000000005181 106.0
XH1_k127_8238069_16 PFAM dihydropteroate synthase, DHPS - - - 4.493e-225 707.0
XH1_k127_8238069_160 ATP synthase subunit C K02124 - - 0.0000000000000000000001296 98.0
XH1_k127_8238069_162 Protein of unknown function (DUF1294) - - - 0.00000000000000009898 83.0
XH1_k127_8238069_163 - - - - 0.000000000000007718 83.0
XH1_k127_8238069_164 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000000003026 70.0
XH1_k127_8238069_165 - - - - 0.00000000001872 67.0
XH1_k127_8238069_166 PFAM PEGA domain - - - 0.00000000005596 66.0
XH1_k127_8238069_167 - - - - 0.00000000005673 72.0
XH1_k127_8238069_168 - - - - 0.000002515 53.0
XH1_k127_8238069_169 - - - - 0.00000272 54.0
XH1_k127_8238069_17 PFAM Thiolase K00626 - 2.3.1.9 4.415e-220 686.0
XH1_k127_8238069_18 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 1.336e-211 663.0
XH1_k127_8238069_19 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 2.178e-211 661.0
XH1_k127_8238069_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1337.0
XH1_k127_8238069_20 PFAM AAA ATPase central domain protein - - - 1.156e-210 661.0
XH1_k127_8238069_21 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.888e-210 658.0
XH1_k127_8238069_22 PFAM ribonuclease II K01147 - 3.1.13.1 4.645e-210 662.0
XH1_k127_8238069_23 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.296e-209 664.0
XH1_k127_8238069_24 AMP-binding enzyme - - - 3.881e-204 644.0
XH1_k127_8238069_25 PFAM SufBD protein K07033 - - 9.31e-203 635.0
XH1_k127_8238069_26 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 1.764e-202 636.0
XH1_k127_8238069_27 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 1.001e-197 619.0
XH1_k127_8238069_28 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 3.45e-197 621.0
XH1_k127_8238069_29 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 5.415e-197 620.0
XH1_k127_8238069_3 DEAD DEAH box helicase K06877 - - 0.0 1168.0
XH1_k127_8238069_30 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 606.0
XH1_k127_8238069_31 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 603.0
XH1_k127_8238069_32 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 587.0
XH1_k127_8238069_33 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 565.0
XH1_k127_8238069_34 Uncharacterised conserved protein UCP033563 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 566.0
XH1_k127_8238069_35 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 560.0
XH1_k127_8238069_36 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 557.0
XH1_k127_8238069_37 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 555.0
XH1_k127_8238069_38 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 528.0
XH1_k127_8238069_39 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 521.0
XH1_k127_8238069_4 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 5e-324 1013.0
XH1_k127_8238069_40 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 524.0
XH1_k127_8238069_41 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 511.0
XH1_k127_8238069_42 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 511.0
XH1_k127_8238069_43 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 497.0
XH1_k127_8238069_44 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 497.0
XH1_k127_8238069_45 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 488.0
XH1_k127_8238069_46 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 480.0
XH1_k127_8238069_47 COG0863 DNA modification methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 480.0
XH1_k127_8238069_48 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 476.0
XH1_k127_8238069_49 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 455.0
XH1_k127_8238069_5 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.872e-305 942.0
XH1_k127_8238069_50 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 446.0
XH1_k127_8238069_51 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 445.0
XH1_k127_8238069_52 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000522 444.0
XH1_k127_8238069_53 DNA methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 441.0
XH1_k127_8238069_54 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 436.0
XH1_k127_8238069_55 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 424.0
XH1_k127_8238069_56 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 396.0
XH1_k127_8238069_57 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 394.0
XH1_k127_8238069_58 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 386.0
XH1_k127_8238069_59 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000828 376.0
XH1_k127_8238069_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.262e-299 925.0
XH1_k127_8238069_60 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 367.0
XH1_k127_8238069_61 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 374.0
XH1_k127_8238069_62 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 368.0
XH1_k127_8238069_63 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 361.0
XH1_k127_8238069_64 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 364.0
XH1_k127_8238069_65 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 358.0
XH1_k127_8238069_66 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 353.0
XH1_k127_8238069_67 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 351.0
XH1_k127_8238069_68 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 341.0
XH1_k127_8238069_69 archaeosine synthase activity K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 345.0
XH1_k127_8238069_7 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 3.866e-293 910.0
XH1_k127_8238069_70 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 337.0
XH1_k127_8238069_71 Domain of unknown function (DUF1917) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 342.0
XH1_k127_8238069_72 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 342.0
XH1_k127_8238069_73 Cysteine-rich small domain K08260 - 3.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 340.0
XH1_k127_8238069_74 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 335.0
XH1_k127_8238069_75 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 325.0
XH1_k127_8238069_76 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 315.0
XH1_k127_8238069_77 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 316.0
XH1_k127_8238069_78 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 309.0
XH1_k127_8238069_79 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 307.0
XH1_k127_8238069_8 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 1.008e-290 899.0
XH1_k127_8238069_80 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
XH1_k127_8238069_81 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 303.0
XH1_k127_8238069_82 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 306.0
XH1_k127_8238069_83 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 299.0
XH1_k127_8238069_84 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 298.0
XH1_k127_8238069_85 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 312.0
XH1_k127_8238069_87 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 297.0
XH1_k127_8238069_88 transferase hexapeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 287.0
XH1_k127_8238069_89 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 283.0
XH1_k127_8238069_9 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 - 1.12.98.1 1.679e-280 865.0
XH1_k127_8238069_90 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 284.0
XH1_k127_8238069_91 Belongs to the UPF0305 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001489 276.0
XH1_k127_8238069_92 Helix-turn-helix domain protein K07731 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000736 272.0
XH1_k127_8238069_93 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003613 276.0
XH1_k127_8238069_94 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001102 276.0
XH1_k127_8238069_95 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005881 260.0
XH1_k127_8238069_96 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 263.0
XH1_k127_8238069_97 PFAM cyclase family protein K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000005012 259.0
XH1_k127_8238069_98 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000001767 254.0
XH1_k127_8238069_99 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000303 249.0
XH1_k127_86429_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000396 280.0
XH1_k127_86429_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006323 242.0
XH1_k127_894309_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 361.0
XH1_k127_894309_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 301.0
XH1_k127_894309_2 RimK-like ATPgrasp N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 299.0
XH1_k127_894309_3 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000004452 244.0
XH1_k127_894309_4 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.00000000000000000000000000000000000000000002516 162.0
XH1_k127_904110_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1065.0
XH1_k127_921373_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1027.0
XH1_k127_921373_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 1.599e-227 721.0
XH1_k127_921373_2 Helix-turn-helix domain protein K03627 - - 0.0000000000000000000000000000000000000000000000000000000000000005069 223.0
XH1_k127_952956_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1327.0
XH1_k127_952956_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 1.067e-203 644.0
XH1_k127_952956_2 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 554.0
XH1_k127_952956_3 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 481.0
XH1_k127_952956_4 PFAM glutamate synthase alpha subunit domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 374.0
XH1_k127_952956_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000005353 158.0
XH1_k127_952956_6 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.000000000000000000000000000000003595 130.0
XH1_k127_952956_7 PFAM Telomeric repeat-binding factor 2 - - - 0.0000872 50.0