Overview

ID MAG04408
Name XH2_bin.19
Sample SMP0119
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus JAJYIS01
Species
Assembly information
Completeness (%) 80.55
Contamination (%) 5.83
GC content (%) 56.0
N50 (bp) 7,689
Genome size (bp) 1,696,465

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1549

Gene name Description KEGG GOs EC E-value Score Sequence
XH2_k127_10150250_0 PFAM SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000001426 222.0
XH2_k127_10150250_1 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000322 138.0
XH2_k127_10150250_2 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 0.0000000000000001134 80.0
XH2_k127_10150250_3 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000006756 61.0
XH2_k127_10152868_0 Belongs to the CarB family K01955 - 6.3.5.5 1.925e-235 747.0
XH2_k127_10152868_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 387.0
XH2_k127_10152868_2 - - - - 0.00000000000000000000000000000000000213 149.0
XH2_k127_10152868_3 EamA-like transporter family - - - 0.0000000000000000000001015 102.0
XH2_k127_10152868_4 YHS domain - - - 0.000000000000000002612 86.0
XH2_k127_10152868_5 COG1522 Transcriptional regulators - - - 0.0000000000000003218 88.0
XH2_k127_10259911_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1274.0
XH2_k127_10259911_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000003165 222.0
XH2_k127_10259911_2 - - - - 0.000000000000000000000000000000000005379 148.0
XH2_k127_10317607_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.425e-232 731.0
XH2_k127_1038370_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 449.0
XH2_k127_1038370_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000008467 236.0
XH2_k127_1038370_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000008844 213.0
XH2_k127_10584319_0 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 608.0
XH2_k127_10584319_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 409.0
XH2_k127_10584319_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001055 201.0
XH2_k127_10584319_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000001523 103.0
XH2_k127_10584319_4 PAS domain K02488 - 2.7.7.65 0.0000000000001507 83.0
XH2_k127_10586336_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 312.0
XH2_k127_10586336_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000003224 231.0
XH2_k127_10586336_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000002534 228.0
XH2_k127_10586336_3 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000003798 196.0
XH2_k127_10586336_4 Double zinc ribbon - - - 0.0000003439 63.0
XH2_k127_1085020_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 425.0
XH2_k127_1085020_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 353.0
XH2_k127_1085020_2 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 326.0
XH2_k127_1085020_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000004325 250.0
XH2_k127_1085020_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000001434 231.0
XH2_k127_1085020_5 Mechanosensitive ion channel K03442,K05802,K16052 - - 0.000000000000000000000000000000000000000000000000000000000008962 227.0
XH2_k127_1085020_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000004454 205.0
XH2_k127_1085020_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000002829 185.0
XH2_k127_1085020_8 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.0000000000000000000000000000005377 133.0
XH2_k127_1098568_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 310.0
XH2_k127_1098568_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000005386 145.0
XH2_k127_1112360_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.844e-215 688.0
XH2_k127_1112360_1 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 557.0
XH2_k127_1112360_2 Beta-lactamase enzyme family K01467,K17836 - 3.5.2.6 0.0000000000000000000000000000008091 136.0
XH2_k127_1112360_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.00000000000000003452 91.0
XH2_k127_1112360_4 meiotic spindle midzone assembly K18626,K20478 GO:0000003,GO:0000070,GO:0000212,GO:0000226,GO:0000278,GO:0000280,GO:0000775,GO:0000776,GO:0000777,GO:0000779,GO:0000793,GO:0000819,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005819,GO:0005856,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007059,GO:0008104,GO:0008150,GO:0008608,GO:0009987,GO:0015630,GO:0016043,GO:0022402,GO:0022414,GO:0022607,GO:0031134,GO:0032991,GO:0033036,GO:0034508,GO:0034622,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044430,GO:0044446,GO:0044464,GO:0045132,GO:0048285,GO:0051179,GO:0051225,GO:0051255,GO:0051257,GO:0051276,GO:0051304,GO:0051306,GO:0051307,GO:0051316,GO:0051321,GO:0051382,GO:0051383,GO:0065003,GO:0065004,GO:0070925,GO:0071824,GO:0071840,GO:0098687,GO:0098813,GO:0140013,GO:0140014,GO:1903046,GO:1903047 - 0.00000000005875 76.0
XH2_k127_1112360_5 DNA polymerase beta domain-containing protein region - - - 0.000008955 55.0
XH2_k127_1138921_0 amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000225 176.0
XH2_k127_1138921_1 nucleic-acid-binding protein containing a Zn-ribbon K00074,K07068 - 1.1.1.157 0.00001912 52.0
XH2_k127_1154263_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 415.0
XH2_k127_1154263_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 350.0
XH2_k127_1205804_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 533.0
XH2_k127_1205804_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 456.0
XH2_k127_1205804_10 - K01992 - - 0.0000003642 61.0
XH2_k127_1205804_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 335.0
XH2_k127_1205804_3 ATPase activity K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001412 277.0
XH2_k127_1205804_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000231 262.0
XH2_k127_1205804_5 PhoU domain - - - 0.000000000000000000000000000000000000000000000000000000000007411 220.0
XH2_k127_1205804_6 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000908 180.0
XH2_k127_1205804_7 ABC-2 family transporter protein K01992 - - 0.00000000001682 74.0
XH2_k127_1205804_8 COG0530 Ca2 Na antiporter K07301 - - 0.00000001332 57.0
XH2_k127_1205804_9 Uncharacterised ArCR, COG2043 - - - 0.0000001318 55.0
XH2_k127_1351207_0 acetyl-CoA hydrolase transferase - - - 4.889e-213 682.0
XH2_k127_1351207_1 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 622.0
XH2_k127_1351207_10 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000001629 191.0
XH2_k127_1351207_11 FeoA K03709 - - 0.000000000000000000000000000000000000000000005086 171.0
XH2_k127_1351207_12 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000001709 178.0
XH2_k127_1351207_13 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000004116 158.0
XH2_k127_1351207_14 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000008771 146.0
XH2_k127_1351207_15 Beta-lactamase enzyme family K07258,K17836 - 3.4.16.4,3.5.2.6 0.0000000000000000001837 100.0
XH2_k127_1351207_2 Citrate transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 458.0
XH2_k127_1351207_3 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 432.0
XH2_k127_1351207_4 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 431.0
XH2_k127_1351207_5 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 410.0
XH2_k127_1351207_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 361.0
XH2_k127_1351207_7 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001311 283.0
XH2_k127_1351207_8 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000001257 243.0
XH2_k127_1351207_9 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000004997 225.0
XH2_k127_1355551_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003862 275.0
XH2_k127_1365645_0 Sodium:solute symporter family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 464.0
XH2_k127_1365645_1 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 369.0
XH2_k127_1365645_2 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000000636 195.0
XH2_k127_1365645_3 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.00000000000000000000000000004567 137.0
XH2_k127_1386033_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 302.0
XH2_k127_1386033_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001602 251.0
XH2_k127_1386033_2 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000002341 136.0
XH2_k127_1386033_3 PKD domain - - - 0.0000000000000000000000000000001607 144.0
XH2_k127_1386033_4 COG1335 Amidases related to nicotinamidase - - - 0.0008562 43.0
XH2_k127_1417008_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000003656 211.0
XH2_k127_1417008_1 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000001332 122.0
XH2_k127_1426256_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000161 164.0
XH2_k127_1426256_1 RDD family - - - 0.00000009861 61.0
XH2_k127_1428923_0 PFAM Phosphoglycerate mutase K02226,K22305 - 3.1.3.3,3.1.3.73 0.0000000000000000000000005046 109.0
XH2_k127_1428923_2 - - - - 0.0007066 46.0
XH2_k127_147166_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.489e-195 622.0
XH2_k127_147166_1 Nickel-dependent hydrogenase K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 347.0
XH2_k127_147166_10 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000000007207 126.0
XH2_k127_147166_11 Stage II sporulation E family protein - - - 0.0000000000000000000000001774 125.0
XH2_k127_147166_12 maturation K03605 - - 0.0001383 51.0
XH2_k127_147166_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007124 271.0
XH2_k127_147166_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000000000299 233.0
XH2_k127_147166_4 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000000001762 224.0
XH2_k127_147166_5 hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000001866 212.0
XH2_k127_147166_6 Phenazine biosynthesis protein phzf family - - - 0.00000000000000000000000000000000000000000000000000000003735 207.0
XH2_k127_147166_7 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000321 183.0
XH2_k127_147166_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000004341 150.0
XH2_k127_147166_9 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000001691 144.0
XH2_k127_147466_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004914 273.0
XH2_k127_147466_1 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000001057 163.0
XH2_k127_147466_2 - - - - 0.000000000000000000000000000000000004345 141.0
XH2_k127_147466_3 PQ loop repeat K15383 - - 0.0000000000000004903 80.0
XH2_k127_147466_4 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000003227 80.0
XH2_k127_147466_5 Acetyltransferase (GNAT) family - - - 0.0000000000005332 81.0
XH2_k127_1500619_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01620 - 2.3.1.29,2.3.1.47,4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 426.0
XH2_k127_1500619_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008743,GO:0009066,GO:0009987,GO:0016043,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 320.0
XH2_k127_1500619_2 FMN binding K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000001461 181.0
XH2_k127_1500619_3 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000832 98.0
XH2_k127_1502830_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000008256 102.0
XH2_k127_1534328_0 nitrogen compound transport K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000001421 207.0
XH2_k127_1534328_1 PFAM peptidase M24 K01262,K01271,K01274 - 3.4.11.9,3.4.13.9 0.000000000007128 73.0
XH2_k127_1534328_2 Cellulose binding domain - - - 0.0000000907 65.0
XH2_k127_153675_0 AAA domain K01338 - 3.4.21.53 5.2e-200 634.0
XH2_k127_153675_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 489.0
XH2_k127_153675_10 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.000000000000000000000000000000000000000000005416 186.0
XH2_k127_153675_11 LysE type translocator - - - 0.000000000000000000000000000000000000000000031 168.0
XH2_k127_153675_12 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000609 106.0
XH2_k127_153675_13 EamA-like transporter family - - - 0.000000000000000009818 94.0
XH2_k127_153675_14 - - - - 0.000000000000008269 86.0
XH2_k127_153675_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000002536 76.0
XH2_k127_153675_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 495.0
XH2_k127_153675_3 Toprim domain K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 445.0
XH2_k127_153675_4 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 394.0
XH2_k127_153675_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 330.0
XH2_k127_153675_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000008074 243.0
XH2_k127_153675_7 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000002497 219.0
XH2_k127_153675_8 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000584 196.0
XH2_k127_153675_9 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000000000000000002828 184.0
XH2_k127_1561376_0 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000006914 177.0
XH2_k127_1561376_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000007286 163.0
XH2_k127_1561376_2 PRC-barrel domain protein - - - 0.00000000000006352 76.0
XH2_k127_1561376_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0004217 42.0
XH2_k127_1578_0 Iron permease FTR1 K07243 - - 0.0000000000000000000000000000000000000000000000000000007349 202.0
XH2_k127_1578_1 MFS/sugar transport protein - - - 0.00000000000000000000000000000002018 134.0
XH2_k127_1578_2 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000008735 89.0
XH2_k127_1578_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000003934 57.0
XH2_k127_1580136_0 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000297 150.0
XH2_k127_1580136_1 PFAM EamA-like transporter family - - - 0.0000000000008888 79.0
XH2_k127_1638042_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 568.0
XH2_k127_1638042_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 540.0
XH2_k127_1638042_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 521.0
XH2_k127_1638042_3 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000009412 263.0
XH2_k127_1638042_4 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000001347 262.0
XH2_k127_1638042_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000002793 187.0
XH2_k127_1699256_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1032.0
XH2_k127_1708333_0 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 362.0
XH2_k127_1708333_1 COG1994 Zn-dependent proteases - - - 0.000000000000000000000000000000000009297 144.0
XH2_k127_1721599_0 Type II/IV secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 426.0
XH2_k127_1721599_1 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000008089 228.0
XH2_k127_1727158_0 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 289.0
XH2_k127_1727158_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 291.0
XH2_k127_1727158_10 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000001308 78.0
XH2_k127_1727158_11 - - - - 0.00000002195 66.0
XH2_k127_1727158_12 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000001389 53.0
XH2_k127_1727158_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000007286 243.0
XH2_k127_1727158_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000006771 211.0
XH2_k127_1727158_4 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000002935 134.0
XH2_k127_1727158_5 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000003531 131.0
XH2_k127_1727158_6 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000008343 124.0
XH2_k127_1727158_7 RNA polymerase subunit 9 K03057 - - 0.000000000000000000000000000225 119.0
XH2_k127_1727158_8 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000001479 98.0
XH2_k127_1727158_9 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000138 91.0
XH2_k127_1731969_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 556.0
XH2_k127_1731969_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008189 278.0
XH2_k127_1731969_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000002967 186.0
XH2_k127_1734141_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000005784 215.0
XH2_k127_1734141_1 nitroreductase - - - 0.0000000000000000000000000000000000000000000002212 172.0
XH2_k127_1734141_2 - - - - 0.00000004199 57.0
XH2_k127_1741403_0 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000002575 179.0
XH2_k127_1741403_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000002828 191.0
XH2_k127_1741403_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000001072 67.0
XH2_k127_1805727_0 'glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 344.0
XH2_k127_1805727_1 PIN domain - - - 0.0000000000000000000000000000000000000000000000000005859 198.0
XH2_k127_1805727_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000002013 167.0
XH2_k127_1805727_4 - - - - 0.0000000000000000000000006456 111.0
XH2_k127_1805727_5 PFAM glutaredoxin - - - 0.00000000000000000001614 94.0
XH2_k127_1835670_0 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000001731 227.0
XH2_k127_1835670_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000000001067 215.0
XH2_k127_1835670_2 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.0000000000000000000000000000000002246 145.0
XH2_k127_1835670_3 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000003716 78.0
XH2_k127_1851515_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000007204 111.0
XH2_k127_1851515_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000107 91.0
XH2_k127_1851515_2 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000004818 70.0
XH2_k127_185540_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002214 285.0
XH2_k127_185540_1 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008839 269.0
XH2_k127_185540_2 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000009972 238.0
XH2_k127_185540_3 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000001956 95.0
XH2_k127_1856066_0 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 349.0
XH2_k127_1856066_1 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000000000000007854 193.0
XH2_k127_1856066_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000006241 100.0
XH2_k127_1856066_3 Protein of unknown function (DUF835) - - - 0.0000000000002198 83.0
XH2_k127_1945882_0 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 349.0
XH2_k127_1945882_1 Spore germination protein K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006749 291.0
XH2_k127_1945882_10 GGDEF domain K02488 - 2.7.7.65 0.0006466 48.0
XH2_k127_1945882_2 VIT family - - - 0.00000000000000000000000000000000000000000000458 174.0
XH2_k127_1945882_3 Right handed beta helix region - - - 0.00000000000000000000000000000000000000003956 168.0
XH2_k127_1945882_4 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000002716 154.0
XH2_k127_1945882_6 Transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000001588 140.0
XH2_k127_1945882_7 Flavodoxin - - - 0.00000000000000000000000007559 114.0
XH2_k127_1945882_8 Transcriptional regulator - - - 0.0000000000000000000009231 106.0
XH2_k127_1945882_9 - - - - 0.00000000000000000009109 98.0
XH2_k127_196939_0 DNA polymerase type-B family K02319 - 2.7.7.7 9.685e-258 817.0
XH2_k127_196939_1 - - - - 0.0000000000008402 81.0
XH2_k127_199393_0 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.00000000000001822 87.0
XH2_k127_199393_1 Alpha-macro-globulin thiol-ester bond-forming region K03910 GO:0000003,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0007565,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0022414,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0032501,GO:0043086,GO:0044092,GO:0044703,GO:0044706,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0051704,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - 0.00000000009742 72.0
XH2_k127_199393_2 Diphthamide synthase K06927 - 6.3.1.14 0.0000001626 53.0
XH2_k127_2011070_0 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 548.0
XH2_k127_2011070_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 329.0
XH2_k127_2011070_10 Nitrous oxidase accessory protein - - - 0.0000000000000129 89.0
XH2_k127_2011070_11 COG1335 Amidases related to nicotinamidase - - - 0.00000000001027 66.0
XH2_k127_2011070_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000009902 64.0
XH2_k127_2011070_13 - - - - 0.0000005095 62.0
XH2_k127_2011070_2 Glycerol-3-phosphate acyltransferase K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 327.0
XH2_k127_2011070_3 myo-inosose-2 dehydratase activity K10709 - - 0.0000000000000000000000000000000000000000001888 170.0
XH2_k127_2011070_4 PFAM SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000003251 160.0
XH2_k127_2011070_5 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000007734 173.0
XH2_k127_2011070_6 - - - - 0.0000000000000000000000000000000000005576 142.0
XH2_k127_2011070_7 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000009202 124.0
XH2_k127_2011070_8 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000001147 101.0
XH2_k127_2011070_9 4Fe-4S binding domain - - - 0.000000000000000004832 91.0
XH2_k127_2024345_0 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 405.0
XH2_k127_2024345_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 353.0
XH2_k127_2024345_10 Protein of unknown function (DUF1614) - - - 0.00000000000000001401 93.0
XH2_k127_2024345_11 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000741 77.0
XH2_k127_2024345_12 COG0477 Permeases of the major facilitator superfamily - - - 0.00000005873 65.0
XH2_k127_2024345_13 deoxyhypusine monooxygenase activity - - - 0.00008467 50.0
XH2_k127_2024345_14 Double zinc ribbon - - - 0.0008092 49.0
XH2_k127_2024345_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001273 268.0
XH2_k127_2024345_3 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000008867 208.0
XH2_k127_2024345_4 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000009584 200.0
XH2_k127_2024345_5 Calcineurin-like phosphoesterase superfamily domain K06953 - - 0.000000000000000000000000000000000000000004502 164.0
XH2_k127_2024345_6 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000007056 154.0
XH2_k127_2024345_7 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000005646 126.0
XH2_k127_2024345_8 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000005619 129.0
XH2_k127_2024345_9 SMART Excinuclease ABC C subunit domain protein - - - 0.0000000000000000000000001296 111.0
XH2_k127_2040000_0 - - - - 0.000000000000000000000000000000000000000000000000000003021 197.0
XH2_k127_2040000_1 PFAM amino acid-binding ACT domain protein - - - 0.0000001614 58.0
XH2_k127_2040000_2 membrane - - - 0.0004079 51.0
XH2_k127_2087066_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 333.0
XH2_k127_2087066_1 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000003709 197.0
XH2_k127_2087066_2 Histone deacetylase domain - - - 0.00000000000000000000000000000002054 133.0
XH2_k127_2109030_0 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 355.0
XH2_k127_2109030_1 PFAM Peptidase family M20 M25 M40 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 312.0
XH2_k127_2109030_2 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000001647 201.0
XH2_k127_2109030_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000007866 116.0
XH2_k127_2109030_4 PKD domain - - - 0.0000000000000000000007126 113.0
XH2_k127_2109030_5 Domain of unknown function (DUF749) - - - 0.00000005233 59.0
XH2_k127_216698_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 420.0
XH2_k127_216698_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000107 157.0
XH2_k127_216698_2 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000000000000000007231 111.0
XH2_k127_216698_3 Pfam:DUF59 - - - 0.000000000000000000006486 95.0
XH2_k127_216698_4 Archaeal Nre, N-terminal - - - 0.0007619 44.0
XH2_k127_2190993_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 396.0
XH2_k127_2190993_1 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 295.0
XH2_k127_2190993_2 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000006014 66.0
XH2_k127_2190993_3 Belongs to the 'phage' integrase family - - - 0.00003051 52.0
XH2_k127_2233087_0 Helix-turn-helix domain - - - 0.00000000000005618 78.0
XH2_k127_2292331_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 316.0
XH2_k127_2292331_1 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 312.0
XH2_k127_2292331_2 molybdopterin synthase activity K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.0000000000000000000000000000009926 126.0
XH2_k127_2292331_3 AAA domain, putative AbiEii toxin, Type IV TA system K16963 - - 0.00000000000001848 79.0
XH2_k127_2292331_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000008203 51.0
XH2_k127_2355554_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 333.0
XH2_k127_2355554_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001255 269.0
XH2_k127_2355554_2 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000001671 208.0
XH2_k127_2355554_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000001365 198.0
XH2_k127_2355554_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000004945 194.0
XH2_k127_2355554_5 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000000007167 153.0
XH2_k127_2355554_6 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000002908 100.0
XH2_k127_2389624_0 GXGXG motif - - - 4.845e-297 936.0
XH2_k127_2389624_1 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 588.0
XH2_k127_2389624_2 Glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 542.0
XH2_k127_2389624_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 331.0
XH2_k127_2389624_4 GAF domain - - - 0.00000000000000000000000000000000000000001947 174.0
XH2_k127_2389624_5 PIN domain - - - 0.00000000000000000000000000000000000002257 153.0
XH2_k127_2389624_7 PFAM glutaredoxin - - - 0.00000000000000000001614 94.0
XH2_k127_2468163_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000001841 231.0
XH2_k127_2468163_1 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000006559 123.0
XH2_k127_2468163_2 - - - - 0.0000000000002422 83.0
XH2_k127_2468163_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001722 64.0
XH2_k127_2499147_0 MCM OB domain K10726 - - 5.287e-215 689.0
XH2_k127_2499147_1 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 527.0
XH2_k127_2499147_10 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000001846 171.0
XH2_k127_2499147_11 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000002785 156.0
XH2_k127_2499147_12 ABC-type cobalt transport system, permease K16785 - - 0.000000000000000000000000000000000001168 148.0
XH2_k127_2499147_13 ECF-type riboflavin transporter, S component - - - 0.000000000000000000000000003559 118.0
XH2_k127_2499147_14 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000007244 111.0
XH2_k127_2499147_15 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000006564 96.0
XH2_k127_2499147_16 RDD family - - - 0.00000000001076 70.0
XH2_k127_2499147_17 Pfam:DUF1628 - - - 0.000004121 55.0
XH2_k127_2499147_2 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 372.0
XH2_k127_2499147_3 Rad51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 324.0
XH2_k127_2499147_4 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 324.0
XH2_k127_2499147_5 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 289.0
XH2_k127_2499147_6 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002724 252.0
XH2_k127_2499147_7 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008959 246.0
XH2_k127_2499147_8 ATPases associated with a variety of cellular activities K16784,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000002473 243.0
XH2_k127_2499147_9 NMD3 family K07562 - - 0.000000000000000000000000000000000000000000000000009887 193.0
XH2_k127_2562883_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009106 514.0
XH2_k127_2562883_1 Ribbon-helix-helix protein, copG family K07722 - - 0.00002263 52.0
XH2_k127_2697314_0 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000002018 201.0
XH2_k127_2697314_1 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000006482 197.0
XH2_k127_2697314_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000004158 150.0
XH2_k127_2709905_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 392.0
XH2_k127_2709905_1 TIGRFAM indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000002927 151.0
XH2_k127_2715939_0 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000006634 267.0
XH2_k127_2715939_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007415 243.0
XH2_k127_2715939_2 Histidine kinase - - - 0.00006359 55.0
XH2_k127_2757951_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.971e-197 625.0
XH2_k127_2757951_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002891 270.0
XH2_k127_2757951_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000001944 235.0
XH2_k127_2757951_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000001249 216.0
XH2_k127_2757951_4 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000002301 227.0
XH2_k127_2757951_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000004424 184.0
XH2_k127_2757951_6 Transcriptional regulator K11924 - - 0.000000000000162 75.0
XH2_k127_2757951_7 - - - - 0.0006191 46.0
XH2_k127_276324_0 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000007128 270.0
XH2_k127_276324_1 - - - - 0.0000000000000000000000000000000000000000000000002659 195.0
XH2_k127_276324_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000002319 109.0
XH2_k127_2776429_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 475.0
XH2_k127_2776429_1 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001799 260.0
XH2_k127_2776429_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000001863 196.0
XH2_k127_2776429_3 - - - - 0.00000000000001057 80.0
XH2_k127_2785804_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 352.0
XH2_k127_2785804_1 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
XH2_k127_2851158_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000002229 236.0
XH2_k127_2851158_2 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000001803 223.0
XH2_k127_2851158_3 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000001664 222.0
XH2_k127_2851158_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000008667 194.0
XH2_k127_2851158_5 PFAM amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000006512 178.0
XH2_k127_2851158_6 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000001808 134.0
XH2_k127_2851158_7 Protein of unknown function (DUF3795) - - - 0.000001289 53.0
XH2_k127_2851288_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 307.0
XH2_k127_2851288_10 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.0000000000000003255 84.0
XH2_k127_2851288_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000005743 69.0
XH2_k127_2851288_12 Protein of unknown function (DUF3795) - - - 0.0000006825 53.0
XH2_k127_2851288_2 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004561 264.0
XH2_k127_2851288_3 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
XH2_k127_2851288_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000401 223.0
XH2_k127_2851288_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000009126 226.0
XH2_k127_2851288_6 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000001026 191.0
XH2_k127_2851288_7 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000004763 179.0
XH2_k127_2851288_8 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000211 156.0
XH2_k127_2851288_9 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000383 132.0
XH2_k127_291074_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 518.0
XH2_k127_291074_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 424.0
XH2_k127_291074_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000007583 229.0
XH2_k127_291074_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000007993 136.0
XH2_k127_291074_4 Protein of unknown function (DUF3795) - - - 0.0000127 51.0
XH2_k127_291074_5 COG0500 SAM-dependent methyltransferases - - - 0.00006563 53.0
XH2_k127_2911212_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 417.0
XH2_k127_2911212_1 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000005096 202.0
XH2_k127_2911212_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000002906 155.0
XH2_k127_2911212_3 Methyltransferase type 11 - - - 0.0000000000000000000000000001005 123.0
XH2_k127_2911212_4 Pfam:DUF59 - - - 0.00000000000005642 75.0
XH2_k127_2913270_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 400.0
XH2_k127_2913270_1 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004635 271.0
XH2_k127_2913270_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000005165 84.0
XH2_k127_2913270_3 - - - - 0.00001897 49.0
XH2_k127_2913285_0 Trehalose utilisation K09992 - - 0.00000004037 65.0
XH2_k127_298022_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001448 275.0
XH2_k127_298022_1 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000002327 217.0
XH2_k127_298022_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000164 190.0
XH2_k127_298022_3 protein conserved in archaea K09723 - - 0.000001126 57.0
XH2_k127_2983119_0 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000001827 207.0
XH2_k127_2983119_1 Right handed beta helix region - - - 0.000000007527 68.0
XH2_k127_2993365_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 362.0
XH2_k127_2993365_1 PFAM Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001087 258.0
XH2_k127_2993365_2 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000002963 182.0
XH2_k127_2994550_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.924e-228 733.0
XH2_k127_2994550_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 467.0
XH2_k127_2994550_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 404.0
XH2_k127_2994550_3 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 313.0
XH2_k127_2994550_4 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000008319 271.0
XH2_k127_2994550_5 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000189 126.0
XH2_k127_2994550_6 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000000007643 78.0
XH2_k127_2994550_7 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000001463 59.0
XH2_k127_2994550_8 - - - - 0.000001368 59.0
XH2_k127_2997038_0 Required for chromosome condensation and partitioning K03529 - - 1.004e-259 843.0
XH2_k127_2997038_1 and related - - - 0.0000000000000000000000000000000000000000000000000000002146 205.0
XH2_k127_2997038_2 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000007296 181.0
XH2_k127_2997038_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000001331 164.0
XH2_k127_2999345_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 3.208e-236 747.0
XH2_k127_2999345_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000278 89.0
XH2_k127_3001934_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0000000000000000009682 101.0
XH2_k127_3008608_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0070011,GO:0070012,GO:0071704,GO:0140096,GO:1901564 3.4.21.83 1.611e-226 719.0
XH2_k127_3008608_1 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 556.0
XH2_k127_3008608_2 Group 1 family - - - 0.00000000000000000000000000000000000000005337 165.0
XH2_k127_3008608_3 membrane transporter protein K07090 - - 0.00000000000002842 84.0
XH2_k127_3013351_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000009874 219.0
XH2_k127_3013351_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.00000000000000000000000000000000000000000000000000000001179 207.0
XH2_k127_3013351_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000005977 197.0
XH2_k127_3013351_3 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000003877 166.0
XH2_k127_3013351_4 Belongs to the PDCD5 family K06875 - - 0.000000000000000000007077 95.0
XH2_k127_3013351_5 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000002666 90.0
XH2_k127_3013351_6 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000287 73.0
XH2_k127_3013351_7 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000001602 51.0
XH2_k127_3013351_8 cheY-homologous receiver domain - - - 0.0001842 54.0
XH2_k127_3062901_0 KH domain K07041 - - 3.651e-270 844.0
XH2_k127_3062901_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.356e-228 721.0
XH2_k127_3062901_2 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 362.0
XH2_k127_3062901_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 318.0
XH2_k127_3062901_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000008594 250.0
XH2_k127_3062901_5 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000001046 132.0
XH2_k127_3062901_6 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000000000000000000004184 108.0
XH2_k127_3065740_0 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 416.0
XH2_k127_3065740_1 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 346.0
XH2_k127_3065740_10 NAD-dependent epimerase dehydratase - - - 0.000000000000001077 86.0
XH2_k127_3065740_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000003979 75.0
XH2_k127_3065740_12 YoaP-like - - - 0.00000000000001288 85.0
XH2_k127_3065740_13 FMN binding - - - 0.000000000503 66.0
XH2_k127_3065740_14 acetyltransferase - - - 0.000000007524 66.0
XH2_k127_3065740_15 - - - - 0.00000002205 63.0
XH2_k127_3065740_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 297.0
XH2_k127_3065740_3 Cysteine desulfurase - - - 0.00000000000000000000000000000000000000000000000000000000003379 221.0
XH2_k127_3065740_4 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000001326 176.0
XH2_k127_3065740_5 - - - - 0.0000000000000000000000000000000000000000000002677 178.0
XH2_k127_3065740_6 Flavodoxin - - - 0.00000000000000000000000000000000003412 139.0
XH2_k127_3065740_7 PFAM Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000008764 119.0
XH2_k127_3065740_8 Mg2 and Co2 transporters K03284 - - 0.000000000000000000001595 106.0
XH2_k127_3065740_9 Winged helix-turn-helix DNA-binding K07730 - - 0.00000000000000000003806 100.0
XH2_k127_306817_0 DNA polymerase alpha chain like domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000101 234.0
XH2_k127_306817_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000001125 213.0
XH2_k127_306817_2 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000001229 195.0
XH2_k127_3100380_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 516.0
XH2_k127_3100380_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 293.0
XH2_k127_3100380_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000002985 165.0
XH2_k127_3115774_0 Type II/IV secretion system protein K07332 - - 6.749e-225 709.0
XH2_k127_3115774_1 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000002454 212.0
XH2_k127_3115774_2 Double zinc ribbon - - - 0.0000000000000000000000000008005 120.0
XH2_k127_3115774_3 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000005099 108.0
XH2_k127_312440_0 Radical SAM superfamily K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 358.0
XH2_k127_312440_1 glutathione-regulated potassium exporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 306.0
XH2_k127_312440_2 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
XH2_k127_312440_3 Lamin Tail Domain - - - 0.00000008596 66.0
XH2_k127_3204494_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 516.0
XH2_k127_3204494_1 - - - - 0.00000002463 58.0
XH2_k127_3204494_2 - - - - 0.00000003677 55.0
XH2_k127_3271680_0 Cobalamin B12-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 565.0
XH2_k127_3271680_1 glycerol-3-phosphate dehydrogenase [NAD(P)+] activity K04940 - 1.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 420.0
XH2_k127_3271680_2 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 298.0
XH2_k127_3271680_3 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001393 289.0
XH2_k127_3271680_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001892 258.0
XH2_k127_3271680_5 COG2335 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.000000000000000000000000000000000000000000006766 166.0
XH2_k127_3271680_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000002156 83.0
XH2_k127_3271680_7 Involved in the tonB-independent uptake of proteins - - - 0.000003054 61.0
XH2_k127_3271680_8 PRC-barrel domain K03886 - - 0.0002561 51.0
XH2_k127_3350621_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 503.0
XH2_k127_3350621_1 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001512 287.0
XH2_k127_3350621_2 Lamin Tail Domain - - - 0.000000000000000000000000000000000000001137 167.0
XH2_k127_3350871_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 567.0
XH2_k127_3350871_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 507.0
XH2_k127_3350871_2 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000855 74.0
XH2_k127_3352370_0 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 333.0
XH2_k127_3352370_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000141 265.0
XH2_k127_3352370_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000000000004406 187.0
XH2_k127_3352370_3 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000915 180.0
XH2_k127_3352370_4 PFAM Pyruvate K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000002201 176.0
XH2_k127_3352370_5 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000000003866 147.0
XH2_k127_3352370_6 Phosphatidylserine decarboxylase K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000007756 141.0
XH2_k127_3352370_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000005619 96.0
XH2_k127_3352662_0 MMPL family K06994 - - 0.0000009622 53.0
XH2_k127_3352662_1 membrane K08978 - - 0.0000293 53.0
XH2_k127_3352662_2 Transcriptional regulator K03718 - - 0.0002207 53.0
XH2_k127_3370431_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004427 260.0
XH2_k127_3370431_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000001804 190.0
XH2_k127_3370431_2 ABC-type dipeptide oligopeptide nickel transport K02034 - - 0.0000000000000000000000000001769 130.0
XH2_k127_3467356_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341,K22167 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 583.0
XH2_k127_3467356_1 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 413.0
XH2_k127_3467356_10 PIN domain of ribonuclease K07060 - - 0.00000000000000000000004835 104.0
XH2_k127_3467356_11 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000001081 95.0
XH2_k127_3467356_12 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000001094 80.0
XH2_k127_3467356_13 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0008033 50.0
XH2_k127_3467356_2 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 393.0
XH2_k127_3467356_3 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 337.0
XH2_k127_3467356_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 326.0
XH2_k127_3467356_5 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 301.0
XH2_k127_3467356_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000001494 235.0
XH2_k127_3467356_7 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000007869 219.0
XH2_k127_3467356_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000001221 119.0
XH2_k127_3467356_9 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.00000000000000000000000001695 118.0
XH2_k127_3557189_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000167 263.0
XH2_k127_3557189_1 indolepyruvate ferredoxin oxidoreductase activity K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000004052 177.0
XH2_k127_3557189_2 - K01992 - - 0.00001111 55.0
XH2_k127_3570754_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 5.568e-223 717.0
XH2_k127_3570754_1 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03768 - 5.2.1.8 0.000000007351 67.0
XH2_k127_3570754_2 ThiS family K03636 - - 0.000002145 53.0
XH2_k127_361388_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 443.0
XH2_k127_361388_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 365.0
XH2_k127_361388_10 - - - - 0.000000000004838 70.0
XH2_k127_361388_11 Protein of unknown function DUF131 - - - 0.0000000007614 65.0
XH2_k127_361388_12 Acetyltransferase (GNAT) domain - - - 0.00000003896 63.0
XH2_k127_361388_2 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001541 261.0
XH2_k127_361388_3 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000009019 247.0
XH2_k127_361388_4 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000000000000000000002144 203.0
XH2_k127_361388_5 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000000000000000000001655 197.0
XH2_k127_361388_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000004894 177.0
XH2_k127_361388_7 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000005552 138.0
XH2_k127_361388_8 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000001964 130.0
XH2_k127_361388_9 - - - - 0.000000000000000000000000007508 122.0
XH2_k127_3660111_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1043.0
XH2_k127_3660111_1 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001542 237.0
XH2_k127_3660111_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000374 242.0
XH2_k127_3690773_0 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 414.0
XH2_k127_3690773_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 312.0
XH2_k127_3690773_2 - - - - 0.0000000000000001579 81.0
XH2_k127_3721728_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 430.0
XH2_k127_3721728_1 Uncharacterized ArCR, COG1888 K09732 - - 0.000000000000000000000000000000009744 128.0
XH2_k127_3721728_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000007807 69.0
XH2_k127_372676_0 PHB de-polymerase C-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 433.0
XH2_k127_372676_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
XH2_k127_372676_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000001019 201.0
XH2_k127_372676_3 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000006543 131.0
XH2_k127_372676_4 - K00960 - 2.7.7.6 0.0000000000000002256 81.0
XH2_k127_372676_5 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000009323 74.0
XH2_k127_372676_6 virion core protein (lumpy skin disease virus) - - - 0.0000000001708 67.0
XH2_k127_372676_7 - - - - 0.000000001719 63.0
XH2_k127_372676_8 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000007037 61.0
XH2_k127_372676_9 SPFH domain-Band 7 family - - - 0.000001032 53.0
XH2_k127_4002385_0 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 431.0
XH2_k127_4002385_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 293.0
XH2_k127_4002385_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000005987 141.0
XH2_k127_4002385_3 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000006174 109.0
XH2_k127_4044947_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.0000000000000000000000000003464 133.0
XH2_k127_4071779_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 398.0
XH2_k127_4071779_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.00000000000000000000000000000000000000000000000000000007201 204.0
XH2_k127_4071779_2 Protein of unknown function (DUF531) K09725 - - 0.000000000000000000000000000000000000000000000000000313 190.0
XH2_k127_4071779_3 helicase superfamily c-terminal domain K03724 - - 0.0000000000000000000000000000000000001278 146.0
XH2_k127_4071779_4 Zinc-binding dehydrogenase - - - 0.00000000002128 65.0
XH2_k127_4074927_0 PFAM SMP-30 Gluconolaconase - - - 0.000000000002131 82.0
XH2_k127_4074927_1 pyrroloquinoline quinone binding - - - 0.00000005536 68.0
XH2_k127_4074927_2 domain protein - - - 0.0004177 51.0
XH2_k127_4085939_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001815 250.0
XH2_k127_4085939_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.000000000000000000000000000000000000000000002169 177.0
XH2_k127_4085939_2 VIT family - - - 0.0000000000000000000000000000000003082 139.0
XH2_k127_4085939_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000002049 128.0
XH2_k127_4085939_4 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000001552 114.0
XH2_k127_4085939_5 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000002569 76.0
XH2_k127_4107589_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 563.0
XH2_k127_4107589_1 PFAM HD domain K03698 - - 0.0000000000000000000000000000000000000000000000000003565 199.0
XH2_k127_4107589_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000001574 119.0
XH2_k127_4107589_4 Domain of unknown function (DUF4382) - - - 0.0001812 47.0
XH2_k127_4117737_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 439.0
XH2_k127_4117737_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000004145 141.0
XH2_k127_4121642_0 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000001926 239.0
XH2_k127_4121642_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000005771 196.0
XH2_k127_4121642_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000008084 177.0
XH2_k127_4121642_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000001378 147.0
XH2_k127_4121642_4 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000005429 93.0
XH2_k127_4121642_5 Domain of unknown function (DU1801) - - - 0.0000000000000000000477 95.0
XH2_k127_4124528_0 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 572.0
XH2_k127_4124528_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000002227 204.0
XH2_k127_4124528_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000006596 129.0
XH2_k127_4124528_3 Ion channel - - - 0.000000000000007556 78.0
XH2_k127_4124528_4 PFAM CBS domain containing protein - - - 0.000000000000243 78.0
XH2_k127_4124611_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 571.0
XH2_k127_4124611_1 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000001017 196.0
XH2_k127_4124611_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000001152 129.0
XH2_k127_4124611_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000004422 83.0
XH2_k127_4124611_4 Ion channel - - - 0.00000000000001036 78.0
XH2_k127_4124611_5 Flavodoxin - - - 0.0000000007749 64.0
XH2_k127_4132947_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008572 379.0
XH2_k127_4132947_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 305.0
XH2_k127_4132947_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000161 258.0
XH2_k127_4132947_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000001148 125.0
XH2_k127_4152400_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 330.0
XH2_k127_4152400_1 COG0604 NADPH quinone reductase and related Zn-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 319.0
XH2_k127_4152400_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000001284 184.0
XH2_k127_4152400_3 - - - - 0.00000000000000000000000000003182 124.0
XH2_k127_4160085_0 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000004978 157.0
XH2_k127_4160085_1 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.000000000000000000000000000000000001347 153.0
XH2_k127_4160085_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000000008071 110.0
XH2_k127_4160085_3 KaiC K08482 - - 0.0000000000106 68.0
XH2_k127_4174746_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 491.0
XH2_k127_4174746_1 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 441.0
XH2_k127_4174746_10 PFAM Major Facilitator Superfamily K19576 - - 0.000000000000000000000000000000000000000000000000000000003963 214.0
XH2_k127_4174746_11 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000006611 189.0
XH2_k127_4174746_12 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000001148 194.0
XH2_k127_4174746_13 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000004097 91.0
XH2_k127_4174746_14 - - - - 0.0000000000005755 71.0
XH2_k127_4174746_2 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 381.0
XH2_k127_4174746_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 374.0
XH2_k127_4174746_4 ABC transporter K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 372.0
XH2_k127_4174746_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 374.0
XH2_k127_4174746_6 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 352.0
XH2_k127_4174746_7 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 290.0
XH2_k127_4174746_8 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002447 294.0
XH2_k127_4174746_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000002331 241.0
XH2_k127_4182789_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 392.0
XH2_k127_4182789_1 PFAM ATP-NAD AcoX kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 317.0
XH2_k127_4182789_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000003133 168.0
XH2_k127_4182789_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000001783 151.0
XH2_k127_4219074_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 503.0
XH2_k127_4219074_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000000000003904 211.0
XH2_k127_4219074_2 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000007853 184.0
XH2_k127_4219074_3 KaiC - - - 0.000000000000000000000000000000000000003412 158.0
XH2_k127_4219074_4 DnaB-like helicase C terminal domain K08482 - - 0.000000000000000000000000000006413 129.0
XH2_k127_4219074_5 - - - - 0.00000000002544 70.0
XH2_k127_4219074_6 EamA-like transporter family - - - 0.0000004328 61.0
XH2_k127_4219074_7 SnoaL-like polyketide cyclase - - - 0.00000108 58.0
XH2_k127_4256613_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000006082 276.0
XH2_k127_4256613_1 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000001476 211.0
XH2_k127_4256613_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000005974 200.0
XH2_k127_4256613_3 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000006745 139.0
XH2_k127_4256613_4 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000004504 96.0
XH2_k127_4277231_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002185 243.0
XH2_k127_4277231_1 - - - - 0.00000000000000000000000000000000004565 151.0
XH2_k127_4277231_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00002196 47.0
XH2_k127_4344577_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009717 341.0
XH2_k127_4344577_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 327.0
XH2_k127_4344577_10 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000003352 103.0
XH2_k127_4344577_11 LemA family K03744 - - 0.00000000000002722 80.0
XH2_k127_4344577_12 - - - - 0.000000000001494 70.0
XH2_k127_4344577_13 to Saccharomyces cerevisiae RPN11 (YFR004W) K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.00000000006987 71.0
XH2_k127_4344577_14 Ubiquitin-conjugating enzyme E2, catalytic domain homologues K13960 GO:0000209,GO:0003674,GO:0003682,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006464,GO:0006513,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0033554,GO:0034641,GO:0035519,GO:0036211,GO:0036297,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044314,GO:0044389,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0051865,GO:0061630,GO:0061631,GO:0061650,GO:0061659,GO:0070013,GO:0070534,GO:0070647,GO:0070936,GO:0070979,GO:0071704,GO:0085020,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.2.23 0.0000000002795 68.0
XH2_k127_4344577_15 tryptophanyl-tRNA aminoacylation K01867 - 6.1.1.2 0.0001032 45.0
XH2_k127_4344577_2 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000007818 229.0
XH2_k127_4344577_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000005685 175.0
XH2_k127_4344577_4 SIS domain K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000003555 176.0
XH2_k127_4344577_5 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000003034 151.0
XH2_k127_4344577_6 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000000000002505 145.0
XH2_k127_4344577_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000007456 128.0
XH2_k127_4344577_8 Methanol dehydrogenase K06872 - - 0.0000000000000000000000003027 114.0
XH2_k127_4344577_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000026 100.0
XH2_k127_4357379_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000003961 196.0
XH2_k127_4357379_1 Tubulin like - - - 0.0000000000000000000000006018 123.0
XH2_k127_4357379_2 modulator of DNA gyrase K03568 - - 0.00000000000000000002101 93.0
XH2_k127_4367077_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 4.46e-321 996.0
XH2_k127_4367077_1 Helix-turn-helix XRE-family like proteins K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 300.0
XH2_k127_4367077_2 - - - - 0.0000000000000000000003547 102.0
XH2_k127_4367077_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000006787 58.0
XH2_k127_4369479_0 CobW/HypB/UreG, nucleotide-binding domain - - - 4.275e-197 622.0
XH2_k127_4369479_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 465.0
XH2_k127_4369479_2 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 308.0
XH2_k127_4369479_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 274.0
XH2_k127_4369479_4 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000004071 221.0
XH2_k127_4369479_5 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.0000000000000000000000000000000000000000000000008012 187.0
XH2_k127_4369479_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000259 133.0
XH2_k127_4369479_7 - - - - 0.000000000000000000000002069 107.0
XH2_k127_4373187_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 409.0
XH2_k127_4373187_1 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000191 116.0
XH2_k127_4373187_2 prohibitin homologues - - - 0.000000000000000000000001478 111.0
XH2_k127_4397304_0 Uncharacterized protein family UPF0004 K15865 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 318.0
XH2_k127_4397304_1 TIGRFAM C_GCAxxG_C_C family protein - - - 0.000000000000000000000004445 106.0
XH2_k127_4397304_2 EamA-like transporter family - - - 0.000000001006 65.0
XH2_k127_4398494_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 300.0
XH2_k127_4398494_1 PAS domain K02488 - 2.7.7.65 0.000000000000000000000004705 109.0
XH2_k127_4398494_2 - - - - 0.0000000000000000003411 102.0
XH2_k127_4398494_3 Response regulator receiver domain K03413 - - 0.0000000000000002991 83.0
XH2_k127_4446711_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 314.0
XH2_k127_4446711_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 285.0
XH2_k127_4446711_2 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000714 289.0
XH2_k127_4446711_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000003965 160.0
XH2_k127_4446711_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000015 106.0
XH2_k127_4446711_5 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000008442 101.0
XH2_k127_4446711_6 - - - - 0.000000000005109 76.0
XH2_k127_4480063_0 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 457.0
XH2_k127_4480063_1 Involved in the catabolism of quinolinic acid (QA) K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002556 261.0
XH2_k127_4480063_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000003442 167.0
XH2_k127_4480063_3 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00000000000261 68.0
XH2_k127_4480063_4 Major facilitator superfamily K08222 - - 0.00003029 56.0
XH2_k127_4488427_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 312.0
XH2_k127_4488427_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0007442 43.0
XH2_k127_4533126_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.45e-303 962.0
XH2_k127_4533126_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 465.0
XH2_k127_4533126_2 Uncharacterised protein family (UPF0147) K09721 - - 0.000000000000000000000000001083 114.0
XH2_k127_4533126_3 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000009731 102.0
XH2_k127_4533126_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000002233 85.0
XH2_k127_4533126_5 - - - - 0.000000000000002312 76.0
XH2_k127_4533126_6 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0005401 43.0
XH2_k127_4561201_0 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 346.0
XH2_k127_4561201_1 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000002869 76.0
XH2_k127_4590658_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 630.0
XH2_k127_4590658_1 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 392.0
XH2_k127_4590658_2 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 361.0
XH2_k127_4590658_3 - - - - 0.0000000000000000000001078 102.0
XH2_k127_4590658_4 PFAM PKD domain containing protein - - - 0.00000000002805 75.0
XH2_k127_4624754_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000005378 142.0
XH2_k127_4624754_1 PFAM Peptidase C11, clostripain - - - 0.00000000000000000000000002195 123.0
XH2_k127_4624754_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000003915 55.0
XH2_k127_4645387_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 349.0
XH2_k127_4645387_1 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 299.0
XH2_k127_4645387_2 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000002161 246.0
XH2_k127_4645387_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000002104 199.0
XH2_k127_4645387_4 - - - - 0.0000000000000000000000000000000000001846 152.0
XH2_k127_4645387_5 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000001181 111.0
XH2_k127_4661217_0 UbiE COQ5 methyltransferase K07755 - 2.1.1.137 0.000000000000003461 85.0
XH2_k127_4661217_1 Iron-containing alcohol dehydrogenase K00005,K00096 - 1.1.1.261,1.1.1.6 0.0000000001911 65.0
XH2_k127_4661217_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000005762 70.0
XH2_k127_4662856_0 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000002666 237.0
XH2_k127_4662856_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000004022 225.0
XH2_k127_4662856_2 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000002218 182.0
XH2_k127_4662856_3 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000003206 130.0
XH2_k127_4662856_4 Cyclophilin-like K09143 - - 0.0000000000000000000000000006551 117.0
XH2_k127_4712283_0 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000000003462 173.0
XH2_k127_4712283_1 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000000000000002032 159.0
XH2_k127_4712283_2 Integral membrane protein DUF92 - - - 0.0000000000000000000000000001111 123.0
XH2_k127_484008_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000001126 274.0
XH2_k127_484008_1 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002648 262.0
XH2_k127_484008_2 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000009634 253.0
XH2_k127_484008_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000001014 242.0
XH2_k127_484008_4 transcription regulator activity - - - 0.00000000000000000000000000000000000000003394 156.0
XH2_k127_4894582_0 COG0531 Amino acid transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 397.0
XH2_k127_4894582_1 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000002003 142.0
XH2_k127_4894582_2 Peptidase family M28 K05994 - 3.4.11.10 0.00000000000000000000000001662 125.0
XH2_k127_4894582_3 nucleotide metabolic process - - - 0.00000000000000000000000004852 118.0
XH2_k127_4894582_4 Domain of unknown function DUF11 - - - 0.00000000000006073 87.0
XH2_k127_4894582_5 cell adhesion involved in biofilm formation - - - 0.0000000000007224 83.0
XH2_k127_4894582_6 OmpA family - - - 0.00000000004475 78.0
XH2_k127_4894628_0 COG0531 Amino acid transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 402.0
XH2_k127_4894628_1 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000001071 142.0
XH2_k127_4894628_2 nucleotide metabolic process - - - 0.0000000000000000000000000294 118.0
XH2_k127_4894628_3 Peptidase family M28 K05994 - 3.4.11.10 0.00000000000000000000000004277 121.0
XH2_k127_4894628_4 OmpA family - - - 0.000000000002669 76.0
XH2_k127_4956693_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1112.0
XH2_k127_4956693_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1077.0
XH2_k127_4956693_10 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000725 260.0
XH2_k127_4956693_11 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000006998 228.0
XH2_k127_4956693_12 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000007897 219.0
XH2_k127_4956693_13 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000007187 216.0
XH2_k127_4956693_14 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000001795 192.0
XH2_k127_4956693_15 - - - - 0.00000000000000000000000000004079 124.0
XH2_k127_4956693_16 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000001175 119.0
XH2_k127_4956693_17 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000001173 88.0
XH2_k127_4956693_18 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000003793 83.0
XH2_k127_4956693_19 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000004409 57.0
XH2_k127_4956693_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.637e-273 857.0
XH2_k127_4956693_3 Belongs to the carbamoyltransferase HypF family K04656 - - 8.031e-194 629.0
XH2_k127_4956693_4 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 488.0
XH2_k127_4956693_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 443.0
XH2_k127_4956693_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 394.0
XH2_k127_4956693_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 360.0
XH2_k127_4956693_8 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008973 347.0
XH2_k127_4956693_9 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 288.0
XH2_k127_497348_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 511.0
XH2_k127_497348_1 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000325 132.0
XH2_k127_497348_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000261 53.0
XH2_k127_507188_0 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 409.0
XH2_k127_507188_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 315.0
XH2_k127_507188_10 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000007398 147.0
XH2_k127_507188_11 molybdopterin synthase activity K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.0000000000000000000000000000005285 126.0
XH2_k127_507188_12 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.0000000000000000000009607 103.0
XH2_k127_507188_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000703 83.0
XH2_k127_507188_14 AAA domain, putative AbiEii toxin, Type IV TA system K16963 - - 0.00000000000008845 77.0
XH2_k127_507188_15 PFAM GGDEF domain containing protein - - - 0.00000000008355 75.0
XH2_k127_507188_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 308.0
XH2_k127_507188_3 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 308.0
XH2_k127_507188_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 299.0
XH2_k127_507188_5 PFAM Metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
XH2_k127_507188_6 oxidoreductase activity K03924,K04748,K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001561 279.0
XH2_k127_507188_7 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000003528 192.0
XH2_k127_507188_8 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000001435 175.0
XH2_k127_507188_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000006776 149.0
XH2_k127_51188_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.942e-275 871.0
XH2_k127_51188_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.098e-264 828.0
XH2_k127_51188_2 DnaB-like helicase C terminal domain - - - 0.0000000000000000000008018 104.0
XH2_k127_51188_3 virion core protein, lumpy skin disease virus - - - 0.0001108 53.0
XH2_k127_515008_0 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000006569 248.0
XH2_k127_515008_1 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.000001345 58.0
XH2_k127_5185957_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 309.0
XH2_k127_5185957_1 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000002227 216.0
XH2_k127_5185957_2 hmm pf03415 K08587 - 3.4.22.8 0.00000000000000000000000000000001528 142.0
XH2_k127_5185957_3 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000007161 115.0
XH2_k127_5311987_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 606.0
XH2_k127_5311987_1 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000005728 97.0
XH2_k127_5311987_2 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000005415 51.0
XH2_k127_5311987_3 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00001187 53.0
XH2_k127_5389481_0 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000003183 210.0
XH2_k127_5389481_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001123 202.0
XH2_k127_5389481_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000173 196.0
XH2_k127_5389481_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000000003336 70.0
XH2_k127_5463763_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 589.0
XH2_k127_5463763_1 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.000000000004374 78.0
XH2_k127_5474028_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 613.0
XH2_k127_5474028_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 533.0
XH2_k127_5474028_2 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000006048 210.0
XH2_k127_5474028_3 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000004488 124.0
XH2_k127_5474028_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000002316 93.0
XH2_k127_5474028_5 4Fe-4S dicluster domain K00124 - - 0.0000000000000000002023 93.0
XH2_k127_5483723_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 342.0
XH2_k127_5483723_1 lactate oxidation K00782,K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001552 302.0
XH2_k127_5483723_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.0000000000000001575 83.0
XH2_k127_5483723_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000647 256.0
XH2_k127_5483723_3 COG0438 Glycosyltransferase K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000000000000000005552 251.0
XH2_k127_5483723_4 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000000000000000000000000000000000000000000000000000002114 220.0
XH2_k127_5483723_5 Membrane - - - 0.0000000000000000000000000000000000000001589 159.0
XH2_k127_5483723_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000003388 138.0
XH2_k127_5483723_7 Universal stress protein family - - - 0.00000000000000000000000000000006185 132.0
XH2_k127_5483723_8 - - - - 0.0000000000000000001179 94.0
XH2_k127_5483723_9 COG0671 Membrane-associated phospholipid phosphatase - - - 0.0000000000000000211 93.0
XH2_k127_5515822_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1748.0
XH2_k127_5515822_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1306.0
XH2_k127_5515822_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000007466 91.0
XH2_k127_5515822_11 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000003708 81.0
XH2_k127_5515822_12 FMN binding - - - 0.00002766 53.0
XH2_k127_5515822_13 CARDB - - - 0.00009504 53.0
XH2_k127_5515822_2 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 1.94e-240 818.0
XH2_k127_5515822_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 419.0
XH2_k127_5515822_4 4Fe-4S single cluster domain K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
XH2_k127_5515822_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000226 247.0
XH2_k127_5515822_6 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000887 209.0
XH2_k127_5515822_7 RNA-binding protein of the translin family K07477 - - 0.000000000000000000000000000000004112 132.0
XH2_k127_5515822_8 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000005323 128.0
XH2_k127_5515822_9 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001678 96.0
XH2_k127_5524004_0 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 364.0
XH2_k127_5524004_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 314.0
XH2_k127_5524004_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K13891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000937 270.0
XH2_k127_5524004_3 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000001886 68.0
XH2_k127_5526543_0 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009587 294.0
XH2_k127_5526543_1 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000214 125.0
XH2_k127_5526543_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000003789 113.0
XH2_k127_5526543_3 ABC transporter K02003 - - 0.0002416 44.0
XH2_k127_5538681_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 5.545e-201 640.0
XH2_k127_5538681_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005107 284.0
XH2_k127_5538681_2 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002375 269.0
XH2_k127_5538681_3 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.000000000000000000000000000000000000000000000000000000000005208 222.0
XH2_k127_5538681_4 Universal stress protein family - - - 0.0000000000000000000000000000007002 130.0
XH2_k127_5538681_5 Membrane - - - 0.0000000000000001034 84.0
XH2_k127_5538681_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000001898 84.0
XH2_k127_5544940_0 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 496.0
XH2_k127_5544940_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 488.0
XH2_k127_5544940_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 459.0
XH2_k127_5544940_3 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000002182 210.0
XH2_k127_5544940_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000007217 177.0
XH2_k127_5549062_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.184e-258 812.0
XH2_k127_5549062_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 5.903e-196 635.0
XH2_k127_5549062_10 Domain of unknown function (DUF4382) - - - 0.000005617 53.0
XH2_k127_5549062_11 KEOPS complex Cgi121-like subunit K09119 - - 0.00003848 52.0
XH2_k127_5549062_2 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 445.0
XH2_k127_5549062_3 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 358.0
XH2_k127_5549062_4 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 350.0
XH2_k127_5549062_5 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003164 261.0
XH2_k127_5549062_6 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000112 248.0
XH2_k127_5549062_7 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.00000000000000000000000000000000000000000000133 171.0
XH2_k127_5549062_8 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000009854 167.0
XH2_k127_5549062_9 Formiminotransferase-cyclodeaminase - - - 0.00000000000000006602 89.0
XH2_k127_5583921_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 1.409e-222 703.0
XH2_k127_5583921_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 1.801e-215 684.0
XH2_k127_5583921_10 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001493 280.0
XH2_k127_5583921_11 Major facilitator superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006888 279.0
XH2_k127_5583921_12 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004912 266.0
XH2_k127_5583921_13 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005637 246.0
XH2_k127_5583921_14 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000004933 243.0
XH2_k127_5583921_15 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000008912 232.0
XH2_k127_5583921_16 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000002655 220.0
XH2_k127_5583921_17 PFAM GvpD gas vesicle - - - 0.000000000000000000000000000000000000000000000001773 192.0
XH2_k127_5583921_18 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000000297 163.0
XH2_k127_5583921_19 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000004335 152.0
XH2_k127_5583921_2 MGS-like domain K00602,K01492 - 2.1.2.2,2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 559.0
XH2_k127_5583921_20 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000006502 126.0
XH2_k127_5583921_21 TIGRFAM molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000003741 125.0
XH2_k127_5583921_22 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000002648 122.0
XH2_k127_5583921_23 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000003385 121.0
XH2_k127_5583921_24 transcriptional regulators - - - 0.000000000000000006558 88.0
XH2_k127_5583921_25 Protein of unknown function (DUF2797) - - - 0.00000000000000002637 92.0
XH2_k127_5583921_26 Belongs to the UPF0273 family - - - 0.0009022 49.0
XH2_k127_5583921_3 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 528.0
XH2_k127_5583921_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 394.0
XH2_k127_5583921_5 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 390.0
XH2_k127_5583921_6 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 384.0
XH2_k127_5583921_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000795 374.0
XH2_k127_5583921_8 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 357.0
XH2_k127_5583921_9 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 357.0
XH2_k127_5588104_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 401.0
XH2_k127_5588104_1 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
XH2_k127_5588104_2 - K00390 - 1.8.4.10,1.8.4.8 0.00000000000000004095 85.0
XH2_k127_5607392_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 317.0
XH2_k127_5607392_1 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.0000000000000000000000000000000004707 139.0
XH2_k127_5607392_2 FecR protein - - - 0.0000002026 59.0
XH2_k127_5608455_0 Radical SAM domain protein K09711 - - 0.000000000000000000000000000000000000000000000000000000000002217 218.0
XH2_k127_5610191_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872,K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.574e-234 747.0
XH2_k127_5610191_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 310.0
XH2_k127_5610191_2 virion core protein (lumpy skin disease virus) - - - 0.0000607 53.0
XH2_k127_5612113_0 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 383.0
XH2_k127_5612113_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 342.0
XH2_k127_5612113_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000008009 87.0
XH2_k127_5612113_3 PFAM Ribosomal LX protein K02944 - - 0.000000006327 59.0
XH2_k127_5612113_4 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000009225 57.0
XH2_k127_5632027_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.917e-253 792.0
XH2_k127_5632027_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.177e-241 752.0
XH2_k127_5632027_10 PFAM 4-vinyl reductase, 4VR K07013 - - 0.00000000000000000008979 93.0
XH2_k127_5632027_11 PFAM Abortive infection protein K07052 - - 0.0006288 52.0
XH2_k127_5632027_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 415.0
XH2_k127_5632027_3 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 369.0
XH2_k127_5632027_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002054 258.0
XH2_k127_5632027_5 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000001275 171.0
XH2_k127_5632027_6 TIGRFAM adenylyl cyclase CyaB K05873 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 4.6.1.1 0.0000000000000000000000000003488 121.0
XH2_k127_5632027_7 RNA binding K09736 - - 0.000000000000000000000000005584 118.0
XH2_k127_5632027_8 GvpD gas vesicle protein - - - 0.0000000000000000000000009205 108.0
XH2_k127_5632027_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000002993 104.0
XH2_k127_5638596_0 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 416.0
XH2_k127_5638596_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 330.0
XH2_k127_5638596_10 - - - - 0.00000000000000000602 90.0
XH2_k127_5638596_11 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000004918 76.0
XH2_k127_5638596_12 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000003519 63.0
XH2_k127_5638596_13 Domain of unknown function (DU1801) - - - 0.00005329 50.0
XH2_k127_5638596_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001972 273.0
XH2_k127_5638596_3 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004236 273.0
XH2_k127_5638596_4 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000000008025 257.0
XH2_k127_5638596_5 peptide-methionine (S)-S-oxide reductase activity K07304,K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001328 233.0
XH2_k127_5638596_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000007336 198.0
XH2_k127_5638596_7 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000007977 181.0
XH2_k127_5638596_8 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000009963 163.0
XH2_k127_5638596_9 Clostripain family - - - 0.0000000000000000000000000009705 127.0
XH2_k127_5647484_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 440.0
XH2_k127_5647484_1 Phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 338.0
XH2_k127_5647484_2 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
XH2_k127_5647484_3 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000001009 219.0
XH2_k127_5647484_4 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000005576 208.0
XH2_k127_5647484_5 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000001757 145.0
XH2_k127_5647484_6 TIGRFAM segregation and condensation protein B K06024 - - 0.000000000000000000000000000000008485 134.0
XH2_k127_5647484_7 snRNP Sm proteins K04796 - - 0.000000000000000000007099 93.0
XH2_k127_5699037_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.318e-282 883.0
XH2_k127_5699037_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 393.0
XH2_k127_5699037_2 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000003155 177.0
XH2_k127_5699037_3 Uncharacterised protein family (UPF0179) K09730 - - 0.00000000000000000000000000000000000001304 148.0
XH2_k127_5699037_4 Response regulator receiver domain - - - 0.00000000000000000000000005289 111.0
XH2_k127_5699037_5 DNA-binding transcription factor activity K18297 - - 0.0000000000000000003328 98.0
XH2_k127_5699037_6 MoaE protein K21142 - 2.8.1.12 0.000000000000003877 79.0
XH2_k127_5699037_7 Contains one ATP-binding region, ATPase-like domain (IPR003594) K03406 - - 0.0000000002274 70.0
XH2_k127_5726678_0 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 338.0
XH2_k127_5726678_1 aminoglycoside K00662 - 2.3.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 296.0
XH2_k127_5726678_2 Immune inhibitor A peptidase M6 - - - 0.0000000000000000000000000000000000000000000002967 179.0
XH2_k127_5764060_0 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002313 252.0
XH2_k127_5764060_1 Fibronectin type III domain - - - 0.000000000000000000000000000000000009304 157.0
XH2_k127_5764060_2 - - - - 0.0000006672 60.0
XH2_k127_5764348_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 450.0
XH2_k127_5764348_1 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000008851 166.0
XH2_k127_5764348_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000003391 137.0
XH2_k127_5764348_3 Protein of unknown function (DUF1616) - - - 0.000000000000000000000004834 109.0
XH2_k127_5766598_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 8.171e-205 647.0
XH2_k127_5766598_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 356.0
XH2_k127_5766598_2 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000006465 171.0
XH2_k127_5766598_3 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.00000000000000000000000000000000028 154.0
XH2_k127_5766598_4 Pfam:DUF552 K09152 - - 0.0000000000000000000000000008992 117.0
XH2_k127_5766598_5 Tetratricopeptide repeat - - - 0.000000000000000000000001139 117.0
XH2_k127_5766598_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000004567 78.0
XH2_k127_5794488_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 483.0
XH2_k127_5794488_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 395.0
XH2_k127_5794488_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000001127 162.0
XH2_k127_5794488_3 Fe-S iron-sulfur cluster assembly protein, NifU family K04488 - - 0.00000000000000000000000001677 110.0
XH2_k127_5794488_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000009961 103.0
XH2_k127_5794488_5 - - - - 0.00000000000003012 79.0
XH2_k127_5794488_6 PRC-barrel domain protein - - - 0.0002612 52.0
XH2_k127_5795430_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 589.0
XH2_k127_5795430_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 480.0
XH2_k127_5795430_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 441.0
XH2_k127_5795430_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001449 250.0
XH2_k127_5795430_4 Methyltransferase domain K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000005078 153.0
XH2_k127_5795430_5 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000006644 143.0
XH2_k127_5795430_6 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000001709 128.0
XH2_k127_5795430_7 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000001964 119.0
XH2_k127_5795430_8 Rhomboid family - - - 0.00000000000000001499 95.0
XH2_k127_5795430_9 ACT domain K01079 - 3.1.3.3 0.0000000000000001521 87.0
XH2_k127_5806470_0 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000001058 202.0
XH2_k127_5806470_1 helix_turn_helix ASNC type K06154 - - 0.00000000000000000000000002545 113.0
XH2_k127_5806470_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.00000000002901 78.0
XH2_k127_5806470_3 - - - - 0.000007108 60.0
XH2_k127_5807392_0 Belongs to the arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 357.0
XH2_k127_5807392_1 - - - - 0.0000000000000000000000000000000000000000001551 172.0
XH2_k127_5807392_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000721 160.0
XH2_k127_5807392_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000002636 128.0
XH2_k127_5807392_4 protein conserved in archaea - - - 0.00000000000000000000000008051 109.0
XH2_k127_5807392_5 PFAM ABC transporter K01990 - - 0.0000000000000000002698 89.0
XH2_k127_5807392_6 - K00960 - 2.7.7.6 0.0000000000000004405 79.0
XH2_k127_5809667_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 539.0
XH2_k127_5809667_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 476.0
XH2_k127_5809667_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 434.0
XH2_k127_5809667_3 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001804 258.0
XH2_k127_5809667_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000002492 186.0
XH2_k127_5809667_5 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000007784 154.0
XH2_k127_5809667_6 transcription activator, effector binding K13652 - - 0.0000000007375 66.0
XH2_k127_5826300_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 569.0
XH2_k127_5826300_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 347.0
XH2_k127_5826300_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 342.0
XH2_k127_5826300_3 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000005237 267.0
XH2_k127_5826300_4 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000000000002729 158.0
XH2_k127_5826300_5 Fcf1 K07158 - - 0.000000000000000000000005542 105.0
XH2_k127_5841871_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 394.0
XH2_k127_5841871_1 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 367.0
XH2_k127_5841871_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000001031 120.0
XH2_k127_5841871_3 PFAM CBS domain - - - 0.00000000000000004059 87.0
XH2_k127_5841871_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000004973 68.0
XH2_k127_5888204_0 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001084 259.0
XH2_k127_5888204_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000003091 124.0
XH2_k127_5916887_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 557.0
XH2_k127_5916887_1 binds to the 23S rRNA K02922 - - 0.0000000000000000007781 86.0
XH2_k127_5954815_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004002 268.0
XH2_k127_5954815_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000002383 206.0
XH2_k127_5954815_2 PKD domain - - - 0.00000000000001661 87.0
XH2_k127_6029342_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 321.0
XH2_k127_6029342_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000008016 261.0
XH2_k127_6029342_2 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000005985 213.0
XH2_k127_6029342_3 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000008714 194.0
XH2_k127_6029342_4 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000001062 173.0
XH2_k127_6029342_5 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000001225 95.0
XH2_k127_6051510_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 378.0
XH2_k127_6051510_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 379.0
XH2_k127_6051510_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 327.0
XH2_k127_6051510_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002 278.0
XH2_k127_6051510_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000529 228.0
XH2_k127_6051510_5 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.0000000000000001272 79.0
XH2_k127_6051510_6 - - - - 0.000000000000002389 79.0
XH2_k127_6064542_0 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 472.0
XH2_k127_6064542_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 336.0
XH2_k127_6064542_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 316.0
XH2_k127_6064542_3 Helix-hairpin-helix motif K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000004499 241.0
XH2_k127_6064542_4 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000509 237.0
XH2_k127_6064542_5 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000001316 117.0
XH2_k127_6064542_6 RNA polymerase K03051 - 2.7.7.6 0.0000000000000000000001523 100.0
XH2_k127_6103016_0 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002466 265.0
XH2_k127_6103016_1 - - - - 0.0000006633 59.0
XH2_k127_6149772_0 glycoside hydrolase, family - - - 5.549e-261 880.0
XH2_k127_6149772_1 - - - - 0.0000000000000000000000000000000000000000001446 172.0
XH2_k127_6149772_2 - - - - 0.000000000000000000000000000000000002082 161.0
XH2_k127_6149772_3 PFAM SMP-30 Gluconolaconase - - - 0.0000000000007469 83.0
XH2_k127_6149772_4 S53, subtilisin kexin sedolisin - - - 0.000003531 61.0
XH2_k127_6164860_0 HELICc2 K03722,K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 490.0
XH2_k127_6164860_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 314.0
XH2_k127_6164860_10 Clostripain family - - - 0.000000000000000000000000006257 128.0
XH2_k127_6164860_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007624 283.0
XH2_k127_6164860_3 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000005194 210.0
XH2_k127_6164860_4 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000001337 190.0
XH2_k127_6164860_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000008268 170.0
XH2_k127_6164860_6 - - - - 0.00000000000000000000000000000000000000000004913 164.0
XH2_k127_6164860_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000003921 165.0
XH2_k127_6164860_8 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000008873 139.0
XH2_k127_6164860_9 Thiamine-binding protein - - - 0.00000000000000000000000000001885 120.0
XH2_k127_6181050_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1049.0
XH2_k127_6181050_1 PFAM Peptidase family M20 M25 M40 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002637 246.0
XH2_k127_6181050_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000001458 206.0
XH2_k127_6181050_3 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000006587 103.0
XH2_k127_6193334_0 ABC transporter K02003 - - 0.00000000008849 63.0
XH2_k127_6193334_1 MacB-like periplasmic core domain K02004 - - 0.0000000006138 73.0
XH2_k127_6193334_2 Tetratricopeptide repeat - - - 0.00003892 55.0
XH2_k127_6236612_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 453.0
XH2_k127_6236612_1 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 419.0
XH2_k127_6236612_2 - - - - 0.000000000000000000000000000000007785 137.0
XH2_k127_6236612_3 spore germination K03605 - - 0.000000000000000000000000002568 118.0
XH2_k127_6236612_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000004761 109.0
XH2_k127_6236612_5 - - - - 0.00000000005273 71.0
XH2_k127_6243199_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 435.0
XH2_k127_6243199_1 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 420.0
XH2_k127_6243199_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 338.0
XH2_k127_6243199_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 296.0
XH2_k127_6243199_4 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000002374 113.0
XH2_k127_6243199_5 prohibitin homologues - - - 0.000000000000000000000001285 111.0
XH2_k127_6243199_6 ribosomal small subunit binding - - - 0.0000003882 60.0
XH2_k127_6275855_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 583.0
XH2_k127_6275855_1 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006164 244.0
XH2_k127_6275855_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000000004329 183.0
XH2_k127_6275855_3 4Fe-4S binding domain - - - 0.00000000000000000000000000003093 122.0
XH2_k127_6275855_4 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000005179 100.0
XH2_k127_6275855_5 Roadblock LC7 family protein K07131 - - 0.000000000000000000004211 96.0
XH2_k127_627706_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 332.0
XH2_k127_627706_1 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000004646 151.0
XH2_k127_628476_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 351.0
XH2_k127_628476_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008503 250.0
XH2_k127_628476_2 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000003026 174.0
XH2_k127_6308342_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 601.0
XH2_k127_6308342_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 357.0
XH2_k127_6308342_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000001446 181.0
XH2_k127_6387941_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 534.0
XH2_k127_6387941_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 328.0
XH2_k127_6387941_2 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003811 283.0
XH2_k127_6387941_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000003476 227.0
XH2_k127_6387941_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000001359 199.0
XH2_k127_6387941_5 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000001101 160.0
XH2_k127_6387941_6 Response regulator receiver domain K03413 - - 0.000000000000000000000279 104.0
XH2_k127_6387941_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000007635 68.0
XH2_k127_6387941_8 but it may be involved in stabilization of the trimeric complex - - - 0.00000000002542 65.0
XH2_k127_6539093_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 403.0
XH2_k127_6539093_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002711 275.0
XH2_k127_6539093_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001759 224.0
XH2_k127_6539093_3 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000002494 120.0
XH2_k127_6539093_4 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.00000000000000000000000000837 114.0
XH2_k127_6539093_5 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.000000003085 63.0
XH2_k127_6709239_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 441.0
XH2_k127_6709239_1 Phosphohydrolase K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004383 250.0
XH2_k127_6709239_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000003399 96.0
XH2_k127_6709239_3 Belongs to the UPF0248 family K09715 - - 0.000000000000000009972 85.0
XH2_k127_6709239_4 EamA-like transporter family - - - 0.000005826 57.0
XH2_k127_6709239_5 EamA-like transporter family - - - 0.00002471 55.0
XH2_k127_6749891_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 566.0
XH2_k127_6749891_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 368.0
XH2_k127_6749891_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 334.0
XH2_k127_6749891_3 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002923 254.0
XH2_k127_6749891_4 - - - - 0.0000000000000000000000000000000000000000000000716 183.0
XH2_k127_6749891_5 Acetyltransferase (GNAT) domain - - - 0.0003676 52.0
XH2_k127_6766490_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 533.0
XH2_k127_6766490_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 439.0
XH2_k127_6766490_10 Bacterial PH domain - - - 0.000000000007255 73.0
XH2_k127_6766490_11 Rubrerythrin - - - 0.0000000001709 68.0
XH2_k127_6766490_12 Pkd domain containing protein - - - 0.00000007786 65.0
XH2_k127_6766490_13 CarboxypepD_reg-like domain - - - 0.0000009876 63.0
XH2_k127_6766490_2 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008795 276.0
XH2_k127_6766490_3 isomerase activity K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006564 259.0
XH2_k127_6766490_4 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005787 263.0
XH2_k127_6766490_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000009129 225.0
XH2_k127_6766490_6 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000000002318 163.0
XH2_k127_6766490_7 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000002987 169.0
XH2_k127_6766490_8 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.000000000000000000000000000000000000004325 168.0
XH2_k127_6766490_9 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000002038 134.0
XH2_k127_6786103_0 PKD domain K08738 - - 0.0001143 55.0
XH2_k127_6790864_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 445.0
XH2_k127_6790864_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 432.0
XH2_k127_6790864_10 - - - - 0.000000000000000000000532 101.0
XH2_k127_6790864_11 - - - - 0.000000000001548 70.0
XH2_k127_6790864_12 Transcription factor zinc-finger - - - 0.00001948 55.0
XH2_k127_6790864_13 Double zinc ribbon - - - 0.0000747 47.0
XH2_k127_6790864_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 332.0
XH2_k127_6790864_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000001121 248.0
XH2_k127_6790864_4 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000000001173 210.0
XH2_k127_6790864_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000003602 169.0
XH2_k127_6790864_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000002556 157.0
XH2_k127_6790864_7 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000000000008016 148.0
XH2_k127_6790864_8 - - - - 0.00000000000000000000000205 103.0
XH2_k127_6790864_9 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000006199 104.0
XH2_k127_6803860_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000003638 213.0
XH2_k127_6803860_1 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000000000000000000000000000003906 209.0
XH2_k127_6803860_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000008195 91.0
XH2_k127_6803860_3 Roadblock/LC7 domain K07131 - - 0.00000001267 61.0
XH2_k127_6825134_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 569.0
XH2_k127_6825134_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004268 290.0
XH2_k127_6825134_2 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001679 267.0
XH2_k127_6825134_3 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000000002859 141.0
XH2_k127_6825134_4 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000003558 138.0
XH2_k127_6825134_5 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000001256 94.0
XH2_k127_6825134_6 - - - - 0.00000000000000003053 91.0
XH2_k127_6833763_0 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 375.0
XH2_k127_6833763_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000001125 212.0
XH2_k127_6833763_2 Conserved region in glutamate synthase - - - 0.00000000000000000000000000001791 124.0
XH2_k127_6876117_0 DEAD/H associated K03724 - - 1.691e-280 884.0
XH2_k127_6876117_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 536.0
XH2_k127_6876117_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 482.0
XH2_k127_6876117_3 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 480.0
XH2_k127_6876117_4 Thioredoxin domain K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 361.0
XH2_k127_6876117_5 PFAM Pyruvate carboxyltransferase K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
XH2_k127_6876117_6 Peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004009 274.0
XH2_k127_6876117_7 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000161 209.0
XH2_k127_6876117_8 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000155 164.0
XH2_k127_6876117_9 - - - - 0.00000000000000000000000000000000007478 143.0
XH2_k127_6910487_0 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 305.0
XH2_k127_6910487_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001461 261.0
XH2_k127_6920293_0 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 293.0
XH2_k127_6920293_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000003747 209.0
XH2_k127_6923885_0 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 377.0
XH2_k127_6923885_1 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
XH2_k127_6923885_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007102 254.0
XH2_k127_6923885_3 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000002564 228.0
XH2_k127_6931120_0 Iron-containing alcohol dehydrogenase K00005 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001551 272.0
XH2_k127_6931120_1 Protein of unknown function TPD sequence-motif - - - 0.000000000000000000000000000000000000000000000000000000000001503 218.0
XH2_k127_6931120_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00003331 46.0
XH2_k127_6936514_0 Heat shock 70 kDa protein K04043 - - 1.502e-269 845.0
XH2_k127_6936514_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 7.207e-233 732.0
XH2_k127_6936514_10 Iron-sulphur cluster biosynthesis K15724 - - 0.0000000000000000383 85.0
XH2_k127_6936514_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000001036 78.0
XH2_k127_6936514_12 - - - - 0.000000001176 61.0
XH2_k127_6936514_13 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000002359 57.0
XH2_k127_6936514_2 helicase superfamily c-terminal domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 587.0
XH2_k127_6936514_3 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 527.0
XH2_k127_6936514_4 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 434.0
XH2_k127_6936514_5 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 402.0
XH2_k127_6936514_6 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000000003124 134.0
XH2_k127_6936514_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000006109 124.0
XH2_k127_6936514_8 protein conserved in archaea - - - 0.000000000000000000009832 99.0
XH2_k127_6936514_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000001973 91.0
XH2_k127_7000739_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 479.0
XH2_k127_7000739_1 Semialdehyde dehydrogenase, NAD binding domain K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 374.0
XH2_k127_7000739_10 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000004896 168.0
XH2_k127_7000739_11 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000000002859 152.0
XH2_k127_7000739_12 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000008475 149.0
XH2_k127_7000739_13 PFAM NIL domain - - - 0.0000000000000000000000000000000001857 136.0
XH2_k127_7000739_14 EamA-like transporter family - - - 0.0000000000000000000000000000000008649 138.0
XH2_k127_7000739_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 373.0
XH2_k127_7000739_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 357.0
XH2_k127_7000739_4 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 343.0
XH2_k127_7000739_5 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 336.0
XH2_k127_7000739_6 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 321.0
XH2_k127_7000739_7 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 316.0
XH2_k127_7000739_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0005488,GO:0036094,GO:0048037,GO:0050661,GO:0050662,GO:0097159,GO:1901265,GO:1901363 1.1.1.25 0.0000000000000000000000000000000000000000000000243 188.0
XH2_k127_7000739_9 prephenate dehydrogenase K04517,K14170,K14187 - 1.3.1.12,4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000002934 179.0
XH2_k127_7024439_0 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000001648 160.0
XH2_k127_7024439_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000449 151.0
XH2_k127_7024439_2 Methyltransferase type 11 - - - 0.0000000000000001309 84.0
XH2_k127_7035173_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 553.0
XH2_k127_7035173_1 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000008399 180.0
XH2_k127_7035173_2 PKD domain - - - 0.000001017 63.0
XH2_k127_7037849_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 411.0
XH2_k127_7037849_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 400.0
XH2_k127_7037849_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 377.0
XH2_k127_7037849_3 ICC-like phosphoesterases K06953 - - 0.00000000000000000000000000000000000000000000000000001887 197.0
XH2_k127_7037849_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000004663 190.0
XH2_k127_7037849_5 Calcineurin-like phosphoesterase superfamily domain K01090 - 3.1.3.16 0.000000000000000000000000000000000000000000000001577 181.0
XH2_k127_7037849_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000001948 139.0
XH2_k127_7037849_7 Double zinc ribbon - - - 0.00001629 57.0
XH2_k127_7037849_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0005539 47.0
XH2_k127_7047876_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000004405 216.0
XH2_k127_7047876_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000002187 195.0
XH2_k127_7047876_2 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000115 189.0
XH2_k127_7047876_3 PBP superfamily domain K05772 - - 0.0000000000000000001977 93.0
XH2_k127_7047876_4 - - - - 0.0000000000000000883 85.0
XH2_k127_7047876_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000002326 87.0
XH2_k127_7047876_6 SPFH domain-Band 7 family - - - 0.00002086 53.0
XH2_k127_7047876_8 - - - - 0.0005941 48.0
XH2_k127_7065702_0 PFAM Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000003093 126.0
XH2_k127_7065702_1 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000247 127.0
XH2_k127_7065702_2 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000001897 97.0
XH2_k127_7065702_3 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000107 95.0
XH2_k127_7065702_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000003174 85.0
XH2_k127_7065702_5 family 5 K02035 - - 0.000000000001752 81.0
XH2_k127_7065702_6 membrane K08978 - - 0.0000000002654 71.0
XH2_k127_7065702_7 DNA-directed RNA polymerase, subunit E K03049 - 2.7.7.6 0.00000005275 54.0
XH2_k127_7090188_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 392.0
XH2_k127_7103918_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 439.0
XH2_k127_7103918_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000000000000000000000009809 200.0
XH2_k127_7103918_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000001018 188.0
XH2_k127_7103918_3 Transcriptional regulator, ArsR family - - - 0.00000000000000000000000000000004403 132.0
XH2_k127_7103918_4 membrane K08971 - - 0.000000000000000000000000001239 128.0
XH2_k127_7103918_5 Belongs to the UPF0248 family K09715 - - 0.000000000000000003852 86.0
XH2_k127_7103918_6 membrane K08978 - - 0.00001187 54.0
XH2_k127_7131184_0 Aminopeptidase Iap family-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002309 291.0
XH2_k127_7131184_1 helix_turn_helix ASNC type - - - 0.000000000007754 76.0
XH2_k127_7147684_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 460.0
XH2_k127_7147684_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006459 280.0
XH2_k127_7210519_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.128e-249 779.0
XH2_k127_7210519_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 584.0
XH2_k127_7210519_2 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 306.0
XH2_k127_7210519_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 291.0
XH2_k127_7210519_4 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000006077 248.0
XH2_k127_7210519_5 - - - - 0.00000000000000000000000000000000000000001511 161.0
XH2_k127_7237655_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 435.0
XH2_k127_7237655_1 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 362.0
XH2_k127_7237655_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003973 274.0
XH2_k127_7237655_3 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000001529 203.0
XH2_k127_7237655_4 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000003067 197.0
XH2_k127_7237655_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000008584 90.0
XH2_k127_7237655_6 protein conserved in archaea - - - 0.000000001569 66.0
XH2_k127_7249843_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 319.0
XH2_k127_7249843_1 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 296.0
XH2_k127_7249843_10 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001613 177.0
XH2_k127_7249843_11 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000002291 154.0
XH2_k127_7249843_12 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002442 145.0
XH2_k127_7249843_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000101 145.0
XH2_k127_7249843_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000001884 135.0
XH2_k127_7249843_15 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000004697 111.0
XH2_k127_7249843_16 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000004361 108.0
XH2_k127_7249843_17 ribosomal protein S14 K02954 - - 0.0000000000000000006866 90.0
XH2_k127_7249843_18 Ribosomal L29 protein K02904 - - 0.000000000000006149 79.0
XH2_k127_7249843_19 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000002643 75.0
XH2_k127_7249843_2 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001306 226.0
XH2_k127_7249843_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000003089 211.0
XH2_k127_7249843_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001185 199.0
XH2_k127_7249843_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000006231 202.0
XH2_k127_7249843_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000007101 201.0
XH2_k127_7249843_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000001926 190.0
XH2_k127_7249843_8 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000002484 191.0
XH2_k127_7249843_9 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000005545 189.0
XH2_k127_729235_0 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000001671 215.0
XH2_k127_729235_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000004082 104.0
XH2_k127_7449695_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 572.0
XH2_k127_7449695_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 300.0
XH2_k127_7449695_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000001139 81.0
XH2_k127_7449695_11 CRS1_YhbY K07574 - - 0.00000001257 60.0
XH2_k127_7449695_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000959 47.0
XH2_k127_7449695_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
XH2_k127_7449695_3 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000499 272.0
XH2_k127_7449695_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000003745 235.0
XH2_k127_7449695_5 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000009977 200.0
XH2_k127_7449695_6 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000005767 173.0
XH2_k127_7449695_7 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000001273 141.0
XH2_k127_7449695_8 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000001797 119.0
XH2_k127_7449695_9 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000003849 91.0
XH2_k127_7493884_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 519.0
XH2_k127_7493884_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 473.0
XH2_k127_7493884_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.00000000000000000000000000000000000000000000000000000000000000000004829 237.0
XH2_k127_7493884_3 transcriptional regulators - - - 0.00000000001986 69.0
XH2_k127_7522739_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 474.0
XH2_k127_7522739_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000009621 196.0
XH2_k127_7522739_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000001009 141.0
XH2_k127_7522739_3 PFAM SMP-30 Gluconolaconase - - - 0.00000009263 66.0
XH2_k127_7522739_4 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00005738 49.0
XH2_k127_7578309_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 336.0
XH2_k127_7578309_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 322.0
XH2_k127_7578309_2 dTDP metabolic process K00943 - 2.7.4.9 0.000000000000000000000000000000000005067 148.0
XH2_k127_7578309_3 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.00000000000000000000000005941 115.0
XH2_k127_7578309_4 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000009209 103.0
XH2_k127_7578309_5 Lrp/AsnC ligand binding domain - - - 0.00000000000008934 74.0
XH2_k127_7599042_0 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000000000000000000000000000001181 248.0
XH2_k127_7599042_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000139 198.0
XH2_k127_7599042_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000000000000000000000000000000000414 177.0
XH2_k127_7599042_3 Putative diguanylate phosphodiesterase - - - 0.000004986 60.0
XH2_k127_7625759_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 372.0
XH2_k127_7625759_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000008223 201.0
XH2_k127_7625759_2 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.0000000000000000000000000406 109.0
XH2_k127_7625759_3 exosome subunit K07581 - - 0.000000000000000000005338 98.0
XH2_k127_766034_0 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002939 272.0
XH2_k127_766034_1 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000001643 76.0
XH2_k127_7666445_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 260.0
XH2_k127_7666445_1 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000001305 232.0
XH2_k127_7769823_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 291.0
XH2_k127_7769823_1 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007986 248.0
XH2_k127_7769823_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000006772 159.0
XH2_k127_7769823_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000002249 154.0
XH2_k127_7769823_4 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000001079 97.0
XH2_k127_7769823_5 - - - - 0.00000000000001464 77.0
XH2_k127_7769823_6 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000166 76.0
XH2_k127_7769823_7 Rubrerythrin - - - 0.000000000005863 74.0
XH2_k127_7769823_8 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.00000000009106 72.0
XH2_k127_7844827_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 306.0
XH2_k127_7844827_1 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000009955 223.0
XH2_k127_7844827_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000003119 87.0
XH2_k127_7854886_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 1.004e-269 855.0
XH2_k127_7854886_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 574.0
XH2_k127_7854886_2 PFAM 4Fe-4S binding domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007804 251.0
XH2_k127_7854886_3 FdhD/NarQ family K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003702 249.0
XH2_k127_7854886_4 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000002248 116.0
XH2_k127_7854886_5 DMSO reductase anchor subunit (DmsC) - - - 0.000000000000000000000002253 115.0
XH2_k127_7854886_6 extracellular matrix structural constituent K02035 - - 0.0000006433 60.0
XH2_k127_7854886_7 Rubrerythrin - - - 0.00000122 57.0
XH2_k127_7854886_8 Acetyltransferase (GNAT) domain - - - 0.000004393 57.0
XH2_k127_7967734_0 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 416.0
XH2_k127_7967734_1 COG COG0714 MoxR-like ATPases General function prediction only - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001394 271.0
XH2_k127_7967734_2 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000002581 192.0
XH2_k127_7967734_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000003015 176.0
XH2_k127_7967734_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000002677 138.0
XH2_k127_7967734_5 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000000000005654 150.0
XH2_k127_7967734_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000001077 86.0
XH2_k127_7967734_7 Bacterio-opsin activator HTH K06930 - - 0.000000000000003438 84.0
XH2_k127_7967734_8 PFAM GGDEF domain containing protein - - - 0.0000000001456 74.0
XH2_k127_8053093_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 567.0
XH2_k127_8053093_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000001707 106.0
XH2_k127_8053093_2 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000007233 68.0
XH2_k127_8122426_0 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000001224 94.0
XH2_k127_8122426_1 Rubrerythrin - - - 0.000000001651 66.0
XH2_k127_8133526_0 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007389 377.0
XH2_k127_8133526_1 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001086 208.0
XH2_k127_8133526_2 Fibronectin type III domain - - - 0.000000000000003195 88.0
XH2_k127_8158652_0 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000007749 195.0
XH2_k127_8158652_1 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000008991 176.0
XH2_k127_8158652_2 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000008357 164.0
XH2_k127_8158652_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000007042 98.0
XH2_k127_8158652_4 Bacterial Ig-like domain (group 3) - - - 0.00000001721 65.0
XH2_k127_8158652_5 - - - - 0.000004138 57.0
XH2_k127_8158652_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0004252 49.0
XH2_k127_8227286_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 505.0
XH2_k127_8227286_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 477.0
XH2_k127_8227286_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000002278 189.0
XH2_k127_8227286_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000008568 97.0
XH2_k127_8227286_4 Tetratricopeptide repeat - - - 0.0000000000000000002613 104.0
XH2_k127_8227286_5 RNA secondary structure unwinding K03724 - - 0.0000000682 66.0
XH2_k127_8227387_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 257.0
XH2_k127_8227387_1 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000002447 160.0
XH2_k127_8227387_2 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000001287 159.0
XH2_k127_8227387_3 flavin reductase - - - 0.00000000000000000000000000000001274 134.0
XH2_k127_8232920_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 584.0
XH2_k127_8232920_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 410.0
XH2_k127_8232920_2 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 297.0
XH2_k127_8232920_3 protein conserved in archaea K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000001122 184.0
XH2_k127_8232920_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000001084 89.0
XH2_k127_8232920_5 Gar1/Naf1 RNA binding region K07569 - - 0.000004529 52.0
XH2_k127_8248775_0 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000003774 139.0
XH2_k127_8248775_1 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000003735 100.0
XH2_k127_8290050_0 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000000000000000000001184 195.0
XH2_k127_8290050_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000005349 139.0
XH2_k127_8290050_2 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000002626 118.0
XH2_k127_8308721_0 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 428.0
XH2_k127_8308721_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007922 276.0
XH2_k127_833832_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 309.0
XH2_k127_833832_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 321.0
XH2_k127_833832_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003964 257.0
XH2_k127_833832_3 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000002578 205.0
XH2_k127_833832_4 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000001623 153.0
XH2_k127_833832_5 - - - - 0.0000000003181 67.0
XH2_k127_8347121_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1247.0
XH2_k127_8347121_1 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000005449 175.0
XH2_k127_8347121_2 the major facilitator superfamily - - - 0.00000004911 66.0
XH2_k127_8418617_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 307.0
XH2_k127_8418617_1 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001766 263.0
XH2_k127_8418617_2 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000003153 143.0
XH2_k127_8418617_3 - - - - 0.0005921 45.0
XH2_k127_8437723_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 599.0
XH2_k127_8437723_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 385.0
XH2_k127_8437723_2 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 349.0
XH2_k127_8437723_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004455 256.0
XH2_k127_8437723_4 SMART MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000002772 188.0
XH2_k127_8437723_5 chemotaxis protein K03406 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000002526 183.0
XH2_k127_8437723_6 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000194 136.0
XH2_k127_8437723_7 PFAM CheW domain protein K03408 - - 0.000000000000000000000000000002905 127.0
XH2_k127_8437723_8 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000001255 112.0
XH2_k127_8514534_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 379.0
XH2_k127_8514534_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000003538 119.0
XH2_k127_8514534_2 repeat-containing protein - - - 0.0000881 54.0
XH2_k127_85264_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 382.0
XH2_k127_85264_1 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.000000000000000000000000000000000000000000000003864 178.0
XH2_k127_854892_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000001668 197.0
XH2_k127_854892_1 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000003216 177.0
XH2_k127_854892_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000002502 131.0
XH2_k127_8603549_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007822 274.0
XH2_k127_8603549_1 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004963 286.0
XH2_k127_8603549_2 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000002026 205.0
XH2_k127_8603549_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000009283 172.0
XH2_k127_8607793_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 495.0
XH2_k127_8656447_0 ABC-type antimicrobial peptide transport system, permease component - - - 0.000000000000000000000107 114.0
XH2_k127_8656447_1 MacB-like periplasmic core domain K02004 - - 0.00009002 54.0
XH2_k127_8701164_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 588.0
XH2_k127_8701164_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 314.0
XH2_k127_8701164_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000001043 207.0
XH2_k127_8701164_3 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000002553 192.0
XH2_k127_8701164_4 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000573 160.0
XH2_k127_8701164_5 NMT1-like family K02051 - - 0.000000000000000000000000000000000000003762 160.0
XH2_k127_8701164_6 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000000000006378 141.0
XH2_k127_8701164_7 - - - - 0.0000000001098 68.0
XH2_k127_8701164_8 redox protein, regulator of disulfide bond formation - - - 0.0000001825 58.0
XH2_k127_8701164_9 Glutamine amidotransferases class-II - - - 0.000002203 59.0
XH2_k127_8724592_0 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001904 235.0
XH2_k127_8724592_1 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000001478 183.0
XH2_k127_8724592_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000002064 73.0
XH2_k127_8784462_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 350.0
XH2_k127_8784462_1 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 299.0
XH2_k127_8784462_2 - - - - 0.00000000000000000000000000000000000002104 154.0
XH2_k127_8784462_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000002967 66.0
XH2_k127_8937584_0 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000003771 237.0
XH2_k127_8937584_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000002207 222.0
XH2_k127_8937584_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.0000000000000000000000000000000000000000000000000000004136 199.0
XH2_k127_8937584_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000011 168.0
XH2_k127_8937584_4 - - - - 0.00000000000000000000000000000000006134 151.0
XH2_k127_8937584_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000006845 58.0
XH2_k127_8952061_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 452.0
XH2_k127_8952061_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 442.0
XH2_k127_8952061_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 338.0
XH2_k127_8952061_3 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 303.0
XH2_k127_8952061_4 Zn-dependent protease with chaperone function K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000003091 244.0
XH2_k127_8952061_5 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000002332 186.0
XH2_k127_8952061_6 Papain family cysteine protease - - - 0.00000000000000005556 94.0
XH2_k127_8952061_7 Histidine kinase-like ATPases - - - 0.000000000000001989 91.0
XH2_k127_8995372_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 5e-324 1016.0
XH2_k127_9234849_0 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000006897 173.0
XH2_k127_9234849_1 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000002185 166.0
XH2_k127_9234849_2 AAA domain, putative AbiEii toxin, Type IV TA system K02193 - 3.6.3.41 0.0000000000000000000000002427 110.0
XH2_k127_9259010_0 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 382.0
XH2_k127_9259010_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 304.0
XH2_k127_9259010_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 288.0
XH2_k127_9259010_3 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001765 276.0
XH2_k127_9259010_4 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000001303 274.0
XH2_k127_9259010_5 Kef-type K transport K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000811 280.0
XH2_k127_9259010_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004671 254.0
XH2_k127_9259010_7 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000001104 179.0
XH2_k127_9259010_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000001554 132.0
XH2_k127_9437041_0 5'-3' exoribonuclease activity K12574 - - 0.000000000000000000000000000000000008338 143.0
XH2_k127_9437041_1 haloacid dehalogenase-like hydrolase K07025 - - 0.000001603 57.0
XH2_k127_9447647_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 479.0
XH2_k127_9447647_1 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 328.0
XH2_k127_9447647_2 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000001115 177.0
XH2_k127_9447647_3 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000003767 169.0
XH2_k127_9447647_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000009353 147.0
XH2_k127_9447647_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000001603 101.0
XH2_k127_9447647_6 PFAM ATP synthase subunit C K02124 - - 0.00000000000005451 74.0
XH2_k127_9447647_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.000000004104 62.0
XH2_k127_9447647_8 membrane-associated protein domain - - - 0.000005306 55.0
XH2_k127_9451342_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 8.92e-282 878.0
XH2_k127_9463642_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 476.0
XH2_k127_9463642_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 401.0
XH2_k127_9463642_2 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 385.0
XH2_k127_9463642_3 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000001063 243.0
XH2_k127_9463642_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000001041 220.0
XH2_k127_9463642_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000005405 112.0
XH2_k127_9463642_6 Transcriptional regulator K07108 - - 0.000006591 53.0
XH2_k127_9469606_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002635 254.0
XH2_k127_9469606_1 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001032 248.0
XH2_k127_9469606_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000006332 169.0
XH2_k127_9469606_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000000000000000000006695 161.0
XH2_k127_9469606_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000001253 131.0
XH2_k127_9487189_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000004218 259.0
XH2_k127_9487189_1 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000001146 127.0
XH2_k127_9487189_2 PFAM DsrE family protein K06039,K07235 - - 0.0006682 47.0
XH2_k127_9494532_0 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 523.0
XH2_k127_9494532_1 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000144 204.0
XH2_k127_9497580_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009704 282.0
XH2_k127_9497580_1 Family 5 K02035,K13889 - - 0.0000000000000000000000000000000000000000000000000000000005015 223.0
XH2_k127_9497580_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000000000009912 203.0
XH2_k127_9497580_3 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.0000000000000000000000000000000000000000000006026 172.0
XH2_k127_9497580_4 PHP-associated - - - 0.00000000000000000000000000000003222 134.0
XH2_k127_9497580_5 COG1100 GTPase SAR1 and related small G - - - 0.000000000000000000000000006128 121.0
XH2_k127_9497580_6 Right handed beta helix region - - - 0.0000000000000001283 89.0
XH2_k127_9540226_0 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 398.0
XH2_k127_9540226_1 FMN binding K03809 - 1.6.5.2 0.00000000000000000000000000000000000000004228 156.0
XH2_k127_9540226_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.0000000000000002054 81.0
XH2_k127_9540226_3 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000273 67.0
XH2_k127_9589251_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 471.0
XH2_k127_9589251_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 469.0
XH2_k127_9589251_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004597 273.0
XH2_k127_9589251_3 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 277.0
XH2_k127_9589251_4 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000001004 98.0
XH2_k127_9589251_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000000009318 70.0
XH2_k127_9596450_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 321.0
XH2_k127_9596450_1 ABC-type Na efflux pump, permease K01992 - - 0.000000000000000000000000000002214 135.0
XH2_k127_9596450_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000123 111.0
XH2_k127_9604878_0 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000009013 241.0
XH2_k127_9604878_1 Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position K01271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.13.9 0.000000000000000000000000000000000000000000000009209 179.0
XH2_k127_9615965_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 555.0
XH2_k127_9615965_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 437.0
XH2_k127_9615965_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 316.0
XH2_k127_9615965_3 PFAM isocitrate isopropylmalate dehydrogenase K10978 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 301.0
XH2_k127_9615965_4 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000335 289.0
XH2_k127_9615965_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000002147 199.0
XH2_k127_9615965_6 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000391 150.0
XH2_k127_9615965_7 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000001486 142.0
XH2_k127_9615965_8 PFAM CBS domain containing protein - - - 0.000000000000000000000000007939 115.0
XH2_k127_9624596_0 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000000004132 136.0
XH2_k127_9624596_1 cell adhesion involved in biofilm formation - - - 0.00000000006815 76.0
XH2_k127_9624596_2 Domain of unknown function DUF11 - - - 0.000001058 63.0
XH2_k127_9639680_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 347.0
XH2_k127_9639680_1 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000001972 173.0
XH2_k127_9639680_2 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000245 168.0
XH2_k127_9639680_3 - - - - 0.000000000000000000000005633 107.0
XH2_k127_9646863_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 411.0
XH2_k127_9646863_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000005178 178.0
XH2_k127_9675444_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000008395 186.0
XH2_k127_9675444_1 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00000000006578 66.0
XH2_k127_9730769_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 7.367e-279 876.0
XH2_k127_9730769_1 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 363.0
XH2_k127_9730769_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004225 270.0
XH2_k127_9730769_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000002409 255.0
XH2_k127_9730769_4 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000005654 199.0
XH2_k127_9730769_5 PFAM Thiamine pyrophosphate enzyme, C-terminal K00170 - 1.2.7.1 0.000000000000000000000000000001811 130.0
XH2_k127_9730769_6 PRC-barrel domain - - - 0.000000000000000000000000004636 112.0
XH2_k127_9730769_7 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000001116 103.0
XH2_k127_9730769_8 SMART Tetratricopeptide repeat - - - 0.00000000000000000001222 106.0
XH2_k127_9730769_9 Glycosyl transferase family 41 - - - 0.0000009822 61.0
XH2_k127_977442_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 529.0
XH2_k127_977442_1 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 516.0
XH2_k127_977442_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 454.0
XH2_k127_977442_3 OsmC-like protein - - - 0.000000000000000000000000000000267 128.0
XH2_k127_977442_4 - - - - 0.00000000000000000000000002959 116.0
XH2_k127_977442_5 alginic acid biosynthetic process K07218 - - 0.0003204 50.0
XH2_k127_9871469_0 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 346.0
XH2_k127_9871469_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 303.0
XH2_k127_9871469_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 289.0
XH2_k127_9871469_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000004614 84.0
XH2_k127_99381_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000002282 218.0
XH2_k127_99381_1 SCP-2 sterol transfer family - - - 0.000000000000000141 83.0
XH2_k127_99381_2 virion core protein (lumpy skin disease virus) - - - 0.00000009592 61.0