Overview

ID MAG04418
Name XH2_bin.38
Sample SMP0119
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Methanomethylicia
Order Methanomethylicales
Family Methanomethylicaceae
Genus JACTUC01
Species
Assembly information
Completeness (%) 90.26
Contamination (%) 1.27
GC content (%) 58.0
N50 (bp) 8,287
Genome size (bp) 1,137,678

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1211

Gene name Description KEGG GOs EC E-value Score Sequence
XH2_k127_10141344_0 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 434.0
XH2_k127_10141344_1 MlaA lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 294.0
XH2_k127_10141344_2 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001111 261.0
XH2_k127_10141344_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000001264 206.0
XH2_k127_10141344_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
XH2_k127_1030778_0 in RNase L inhibitor, RLI K06174 - - 1.046e-204 655.0
XH2_k127_1030778_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000001843 211.0
XH2_k127_1030778_2 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.0000000000000000000000000000000000000000000003633 177.0
XH2_k127_1030778_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.00000000000000000000000000000000000009681 151.0
XH2_k127_1030778_4 THUMP domain K06963 - - 0.000000000000000000000000000001772 126.0
XH2_k127_1030778_5 PFAM ParB domain protein nuclease - - - 0.00000000000000000000001272 108.0
XH2_k127_1030778_6 SMART DNA-directed RNA polymerase, M 15 kDa subunit K03057 - - 0.00000000000005313 75.0
XH2_k127_1030778_7 ThiS family K03636 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000002028 63.0
XH2_k127_1030778_8 KEOPS complex Cgi121-like subunit K09119 - - 0.00000002256 63.0
XH2_k127_10356366_0 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 311.0
XH2_k127_10356366_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000003827 252.0
XH2_k127_1037890_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 451.0
XH2_k127_1037890_1 PFAM isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 360.0
XH2_k127_1037890_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 319.0
XH2_k127_1037890_3 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
XH2_k127_10629055_0 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 374.0
XH2_k127_10629055_1 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000002713 162.0
XH2_k127_10629055_2 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000000000000000000001062 151.0
XH2_k127_10629055_3 PFAM glutaredoxin - - - 0.000000000000000007429 87.0
XH2_k127_10682683_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 289.0
XH2_k127_10682683_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001083 270.0
XH2_k127_10682683_10 PFAM regulatory protein AsnC Lrp family K03718 - - 0.00000000000000001153 88.0
XH2_k127_10682683_11 Sulfurtransferase TusA - - - 0.0000000000004377 75.0
XH2_k127_10682683_12 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000000003076 72.0
XH2_k127_10682683_13 PFAM DsrE family protein K07235 - - 0.00009831 53.0
XH2_k127_10682683_2 ERCC4 domain K10896 - - 0.000000000000000000000000000000000000000000000008766 181.0
XH2_k127_10682683_3 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000004265 172.0
XH2_k127_10682683_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000001497 163.0
XH2_k127_10682683_5 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000439 154.0
XH2_k127_10682683_6 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000127 153.0
XH2_k127_10682683_7 PFAM thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000003759 141.0
XH2_k127_10682683_8 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000008977 111.0
XH2_k127_10682683_9 Belongs to the UPF0147 family K09721 - - 0.000000000000000000007252 97.0
XH2_k127_1088015_0 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 405.0
XH2_k127_1088015_1 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 310.0
XH2_k127_1088015_10 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000902 158.0
XH2_k127_1088015_11 EamA-like transporter family - - - 0.00000000000000121 87.0
XH2_k127_1088015_12 Transcriptional regulator K07722 - - 0.0000000004025 65.0
XH2_k127_1088015_13 Psort location Cytoplasmic, score - - - 0.0000003706 56.0
XH2_k127_1088015_2 PFAM Phosphoribosyltransferase K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 304.0
XH2_k127_1088015_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 302.0
XH2_k127_1088015_4 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000001673 232.0
XH2_k127_1088015_5 SMART Elongator protein 3 MiaB NifB K06935 - - 0.00000000000000000000000000000000000000000000000000000000000002088 222.0
XH2_k127_1088015_6 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K01101 - 3.1.3.41 0.00000000000000000000000000000000000000000000000000000000002335 214.0
XH2_k127_1088015_7 Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000009331 215.0
XH2_k127_1088015_8 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000001723 186.0
XH2_k127_1088015_9 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000001196 166.0
XH2_k127_1244966_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.072e-308 975.0
XH2_k127_1244966_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.187e-245 788.0
XH2_k127_1244966_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000002477 115.0
XH2_k127_1244966_11 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000781 117.0
XH2_k127_1244966_12 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001326 106.0
XH2_k127_1244966_13 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000001937 58.0
XH2_k127_1244966_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0004845 45.0
XH2_k127_1244966_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.264e-214 680.0
XH2_k127_1244966_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 331.0
XH2_k127_1244966_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000003631 216.0
XH2_k127_1244966_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000006428 202.0
XH2_k127_1244966_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K00390,K14108 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000004058 200.0
XH2_k127_1244966_7 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001823 198.0
XH2_k127_1244966_8 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000008813 155.0
XH2_k127_1244966_9 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000001741 138.0
XH2_k127_1396947_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 407.0
XH2_k127_1396947_1 - - - - 0.0000000000000000002286 94.0
XH2_k127_1475492_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 326.0
XH2_k127_1475492_1 Radical SAM domain protein K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000003872 233.0
XH2_k127_1475492_2 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000001555 217.0
XH2_k127_1475492_3 - - - - 0.000000000004777 76.0
XH2_k127_1475492_4 COG1522 Transcriptional regulators - - - 0.00001145 50.0
XH2_k127_1475492_5 Lrp/AsnC ligand binding domain - - - 0.00002072 49.0
XH2_k127_1475492_6 Lipoate-protein ligase a K03800 - 6.3.1.20 0.00009892 51.0
XH2_k127_1476519_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.621e-222 703.0
XH2_k127_1476519_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.593e-203 642.0
XH2_k127_1476519_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14120 - - 0.00000000000000000000000000001472 126.0
XH2_k127_1476519_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000002817 110.0
XH2_k127_1476519_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K14114 - - 0.0000000000000000002932 96.0
XH2_k127_1476519_13 PFAM cation antiporter K14110 - - 0.00000000000000004614 84.0
XH2_k127_1476519_14 Putative Fe-S cluster K03616 - - 0.0000000000000004323 87.0
XH2_k127_1476519_15 Domain of unknown function (DUF4040) K14113 - - 0.0000000000001291 73.0
XH2_k127_1476519_16 PFAM Energy-converting hydrogenase B, subunit P K14125 - - 0.000000000002002 70.0
XH2_k127_1476519_17 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.000000000008962 70.0
XH2_k127_1476519_18 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000002801 65.0
XH2_k127_1476519_19 Archaeal vacuolar-type H -ATPase subunit F K02122 - - 0.00000000006788 66.0
XH2_k127_1476519_2 Hydrogenase K14123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 413.0
XH2_k127_1476519_20 Multisubunit Na H antiporter K14117 - - 0.000000001722 68.0
XH2_k127_1476519_21 ATP synthase (C/AC39) subunit K02119 - - 0.000000008733 66.0
XH2_k127_1476519_22 - K14116 - - 0.0002533 49.0
XH2_k127_1476519_23 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0006388 50.0
XH2_k127_1476519_24 monovalent cation:proton antiporter activity K14112 - - 0.0009782 49.0
XH2_k127_1476519_25 PFAM Multiple resistance and pH regulation protein F K14111 - - 0.0009868 47.0
XH2_k127_1476519_3 Proton-conducting membrane transporter K14115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004487 285.0
XH2_k127_1476519_4 NADH dehydrogenase K14124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001317 271.0
XH2_k127_1476519_5 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000003059 232.0
XH2_k127_1476519_6 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14122 - - 0.0000000000000000000000000000000000000000000000000000002239 198.0
XH2_k127_1476519_7 ATP hydrolysis coupled proton transport K02123 - - 0.00000000000000000000000000000000000000000008133 181.0
XH2_k127_1476519_8 4Fe-4S dicluster domain K14121 - - 0.00000000000000000000000000000000000004119 148.0
XH2_k127_1476519_9 4Fe-4S dicluster domain K14120 - - 0.0000000000000000000000000000001923 128.0
XH2_k127_154508_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 356.0
XH2_k127_154508_1 Serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001129 229.0
XH2_k127_154508_2 Pfam:KH_3 K06961 - - 0.0000000000000000000000000000000000000000000000003161 184.0
XH2_k127_154508_3 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000000000000000000111 193.0
XH2_k127_154508_4 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000006877 178.0
XH2_k127_154508_5 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000005094 115.0
XH2_k127_1555519_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 589.0
XH2_k127_1555519_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 550.0
XH2_k127_1555519_10 RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000002264 209.0
XH2_k127_1555519_11 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000006281 184.0
XH2_k127_1555519_12 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000166 182.0
XH2_k127_1555519_13 RIO1 family K08851 - 2.7.11.1 0.000000000000000000000000000000000000000000000004914 179.0
XH2_k127_1555519_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000001991 173.0
XH2_k127_1555519_15 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000008049 156.0
XH2_k127_1555519_16 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000001511 127.0
XH2_k127_1555519_17 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000003375 117.0
XH2_k127_1555519_18 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000003484 117.0
XH2_k127_1555519_19 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000001061 113.0
XH2_k127_1555519_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 531.0
XH2_k127_1555519_20 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000000004411 105.0
XH2_k127_1555519_21 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.00000000000000000001344 101.0
XH2_k127_1555519_22 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000005006 78.0
XH2_k127_1555519_23 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000007758 76.0
XH2_k127_1555519_24 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000002302 76.0
XH2_k127_1555519_25 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000002652 73.0
XH2_k127_1555519_26 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000006512 61.0
XH2_k127_1555519_27 Nucleotide binding protein, PINc K07158 GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0004237 48.0
XH2_k127_1555519_28 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.0008178 50.0
XH2_k127_1555519_29 - - - - 0.0008789 47.0
XH2_k127_1555519_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 516.0
XH2_k127_1555519_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 387.0
XH2_k127_1555519_5 COG0608 Single-stranded DNA-specific exonuclease K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 338.0
XH2_k127_1555519_6 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 326.0
XH2_k127_1555519_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000004433 263.0
XH2_k127_1555519_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001247 261.0
XH2_k127_1555519_9 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000009161 228.0
XH2_k127_1587446_0 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 603.0
XH2_k127_1587446_1 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001436 251.0
XH2_k127_1587446_2 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000001172 157.0
XH2_k127_1587446_3 Rubredoxin - - - 0.00000000000000000007141 89.0
XH2_k127_1587446_4 Amino acid synthesis - - - 0.000000000000001203 78.0
XH2_k127_1596657_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 423.0
XH2_k127_1596657_1 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 417.0
XH2_k127_1596657_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
XH2_k127_1596657_3 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001005 220.0
XH2_k127_1596657_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
XH2_k127_1596657_5 Universal stress protein - - - 0.00000000000003332 78.0
XH2_k127_1596657_6 COG1522 Transcriptional regulators - - - 0.0000000000007236 71.0
XH2_k127_1596657_7 - - - - 0.00000000000182 72.0
XH2_k127_1596657_8 Cytochrome c biogenesis protein K06196 - - 0.000000006457 64.0
XH2_k127_1596657_9 Thioredoxin-like - - - 0.0004983 49.0
XH2_k127_167781_0 Belongs to the glycosyl hydrolase 57 family K06044 - 5.4.99.15 6.689e-204 645.0
XH2_k127_167781_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 485.0
XH2_k127_167781_2 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008035 271.0
XH2_k127_167781_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000001041 130.0
XH2_k127_1683868_0 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000149 254.0
XH2_k127_17354_0 FeS assembly protein SUFB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 375.0
XH2_k127_17354_1 assembly ATPase K09013 - - 0.00000000000000000000000000000000000000000000000000000003543 205.0
XH2_k127_17354_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000003785 200.0
XH2_k127_17354_3 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000001087 192.0
XH2_k127_17354_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000005925 72.0
XH2_k127_1742031_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 2.732e-247 779.0
XH2_k127_1742031_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000001289 233.0
XH2_k127_1742031_2 - - - - 0.0000000000000000000000000000000000000000000000000000007735 202.0
XH2_k127_1742031_3 Methyltransferase type 11 - - - 0.0000000000000000000000006626 115.0
XH2_k127_1742031_4 GYD domain - - - 0.0004482 48.0
XH2_k127_1755327_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 512.0
XH2_k127_1755327_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 462.0
XH2_k127_1755327_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
XH2_k127_1755327_3 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006388 273.0
XH2_k127_1755327_4 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
XH2_k127_1755327_5 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001146 255.0
XH2_k127_1755327_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001276 256.0
XH2_k127_1755327_7 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000001295 168.0
XH2_k127_1755327_8 sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000003074 166.0
XH2_k127_1755327_9 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000004833 137.0
XH2_k127_1928183_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 309.0
XH2_k127_1928183_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 289.0
XH2_k127_1928183_2 PFAM phosphoribosyltransferase K07101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008923 246.0
XH2_k127_1928183_3 hydroxymethylpyrimidine transporter CytX - - - 0.000000000000000000000000000000000000000000000000000000000000000001443 243.0
XH2_k127_1928183_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000003831 227.0
XH2_k127_1928183_5 Major Facilitator Superfamily - - - 0.00000000000000000000000002629 123.0
XH2_k127_1960159_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 431.0
XH2_k127_1960159_1 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 316.0
XH2_k127_1960159_10 Signal recognition particle K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005786,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006617,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0022607,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0042886,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0065003,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:1901363,GO:1990904 - 0.00000000002681 72.0
XH2_k127_1960159_11 COG1522 Transcriptional regulators - - - 0.0000000009761 65.0
XH2_k127_1960159_12 Gar1/Naf1 RNA binding region K07569 - - 0.00000001654 61.0
XH2_k127_1960159_13 Belongs to the UPF0216 family K09737 - - 0.000001425 55.0
XH2_k127_1960159_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 293.0
XH2_k127_1960159_3 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001648 254.0
XH2_k127_1960159_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000006231 202.0
XH2_k127_1960159_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000001106 180.0
XH2_k127_1960159_6 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000002161 166.0
XH2_k127_1960159_7 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000002357 141.0
XH2_k127_1960159_8 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000001429 137.0
XH2_k127_1960159_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000009661 76.0
XH2_k127_1965757_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 428.0
XH2_k127_1965757_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
XH2_k127_1965757_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000003694 229.0
XH2_k127_1965757_3 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000001347 181.0
XH2_k127_1965757_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000006032 168.0
XH2_k127_1965757_5 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000005795 113.0
XH2_k127_1965757_6 Universal stress protein - - - 0.000000000000000000001336 100.0
XH2_k127_1965757_8 membrane K09167 - - 0.00000000000000000004248 98.0
XH2_k127_1974113_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 3.308e-202 640.0
XH2_k127_1974113_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 447.0
XH2_k127_1974113_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000000000009516 214.0
XH2_k127_1974113_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000002254 95.0
XH2_k127_1974113_4 Methionine sulfoxide reductase B3 K07305 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005783,GO:0005829,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0012505,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033743,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:1901564 1.8.4.12 0.00000000000002537 72.0
XH2_k127_1974113_5 EamA-like transporter family - - - 0.00000000002896 74.0
XH2_k127_2032251_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 538.0
XH2_k127_2032251_1 glycosyl transferase group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 414.0
XH2_k127_2032251_2 TIGRFAM TIGR00266 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 318.0
XH2_k127_2032251_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000001645 138.0
XH2_k127_2032251_4 Rieske 2Fe-2S K05710 - - 0.00000000000000000008144 92.0
XH2_k127_2032251_5 membrane - - - 0.00000000000004773 76.0
XH2_k127_2032251_6 Membrane-bound serine protease (ClpP class) K07403 - - 0.00000003242 60.0
XH2_k127_2032251_7 Glycosyltransferase - - - 0.000002697 53.0
XH2_k127_2048448_0 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009219 358.0
XH2_k127_2048448_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002569 262.0
XH2_k127_2048448_2 NADH ubiquinone oxidoreductase, 20 K00331,K14088 - 1.6.5.3 0.00000000000000000000000000000000000000000000006199 173.0
XH2_k127_2048448_3 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000006289 164.0
XH2_k127_2048448_4 CoB--CoM heterodisulfide reductase subunit B - - - 0.0000000000000000000000000000000002448 137.0
XH2_k127_2048448_5 4Fe-4S binding domain K12143 - - 0.00000000000000000000002932 107.0
XH2_k127_2075035_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 528.0
XH2_k127_2075035_1 - K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 377.0
XH2_k127_2075035_2 Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity K01611 - 4.1.1.50 0.000000000000000000000000000000000000000006433 157.0
XH2_k127_2075035_3 Winged helix-turn-helix - - - 0.0000000000000000000000224 107.0
XH2_k127_2075035_4 COGs COG3377 conserved - - - 0.00000000000000000003592 93.0
XH2_k127_2075035_5 - - - - 0.000000000000002671 83.0
XH2_k127_2075035_6 N2,N2-dimethylguanosine tRNA methyltransferase K00555 - 2.1.1.215,2.1.1.216 0.0000000000000906 76.0
XH2_k127_2075035_7 ribosomal protein S30 K02983 - - 0.000000000001275 68.0
XH2_k127_2113075_0 Uncharacterised nucleotidyltransferase - - - 0.000004261 58.0
XH2_k127_2113262_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.301e-202 647.0
XH2_k127_2113262_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 408.0
XH2_k127_2113262_2 riboflavin transmembrane transporter activity - - - 0.0006794 49.0
XH2_k127_2194195_0 Arginase family - - - 0.000000000000000000000000000000000000000000000000000000000000000004292 237.0
XH2_k127_2194195_1 methyltransferase - - - 0.00000000000000000000000004852 118.0
XH2_k127_2194195_2 Protein of unknown function (DUF4013) - - - 0.0000000001199 74.0
XH2_k127_2194195_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0001969 52.0
XH2_k127_228130_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 394.0
XH2_k127_228130_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 294.0
XH2_k127_228130_2 Multidrug MFS transporter K19576,K19578 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000006982 126.0
XH2_k127_228130_3 PFAM PspC domain K03973 - - 0.00000000000000001635 92.0
XH2_k127_2316928_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000001328 215.0
XH2_k127_2316928_1 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000000000000000003074 180.0
XH2_k127_2316928_2 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000005367 107.0
XH2_k127_2316928_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000003606 92.0
XH2_k127_2316928_4 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002268 68.0
XH2_k127_2316928_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000006415 70.0
XH2_k127_2316928_6 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00002192 53.0
XH2_k127_2316928_7 PFAM Ribosomal L18ae LX protein domain K02944 - - 0.00002387 48.0
XH2_k127_2327294_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 309.0
XH2_k127_2327294_1 Lysine biosynthesis K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000139 212.0
XH2_k127_2327294_2 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000000000000000004397 210.0
XH2_k127_2327294_3 helix_turn_helix ASNC type - - - 0.000000000000000000000000000002161 124.0
XH2_k127_2327294_4 Membrane protein of 12 TMs K01992,K07087 - - 0.000000000000004407 89.0
XH2_k127_2349585_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 407.0
XH2_k127_2349585_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 324.0
XH2_k127_2349585_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000001161 144.0
XH2_k127_2349585_11 Binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000001291 139.0
XH2_k127_2349585_12 Binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002427 139.0
XH2_k127_2349585_13 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000006109 133.0
XH2_k127_2349585_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000003737 120.0
XH2_k127_2349585_15 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000002008 121.0
XH2_k127_2349585_16 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000682 94.0
XH2_k127_2349585_17 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.000000000000000001918 85.0
XH2_k127_2349585_18 membrane - - - 0.00000000005773 70.0
XH2_k127_2349585_2 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005781 271.0
XH2_k127_2349585_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002384 199.0
XH2_k127_2349585_4 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001501 192.0
XH2_k127_2349585_5 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000003723 192.0
XH2_k127_2349585_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000006747 185.0
XH2_k127_2349585_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000003132 164.0
XH2_k127_2349585_8 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000003757 149.0
XH2_k127_2349585_9 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000005376 154.0
XH2_k127_2400079_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 344.0
XH2_k127_2400079_1 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000004829 237.0
XH2_k127_2400079_2 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.000000000000000000000000000000000000000000000001772 179.0
XH2_k127_2400079_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000002028 178.0
XH2_k127_2400079_4 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000005131 178.0
XH2_k127_2400079_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000004209 133.0
XH2_k127_2400079_6 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000004052 115.0
XH2_k127_2400079_7 Lrp/AsnC ligand binding domain - - - 0.000000000004423 69.0
XH2_k127_2400079_8 transglutaminase domain protein - - - 0.00000000002327 76.0
XH2_k127_2400079_9 PFAM CBS domain K04767 - - 0.0009869 50.0
XH2_k127_2424908_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 484.0
XH2_k127_2424908_1 Quinolinate phosphoribosyl transferase, N-terminal domain K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 436.0
XH2_k127_2424908_2 - - - - 0.000000000000000000000000000000000000000000000000001252 191.0
XH2_k127_2424908_3 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000006062 181.0
XH2_k127_2424908_4 Ser thr protein kinase K07176 - - 0.0000000000000000000000000000000000000004592 159.0
XH2_k127_2424908_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000006 153.0
XH2_k127_2424908_6 redox protein, regulator of disulfide bond formation K07397 - - 0.00000000000888 71.0
XH2_k127_2424908_7 Putative zinc- or iron-chelating domain K06940 - - 0.00000000003254 69.0
XH2_k127_2424908_8 acetyltransferase - - - 0.0001137 53.0
XH2_k127_2424908_9 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.0009008 48.0
XH2_k127_2576109_0 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13328 - 1.17.1.1,4.2.1.164 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 435.0
XH2_k127_2576109_1 epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000003237 167.0
XH2_k127_2746010_0 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000008933 231.0
XH2_k127_2746010_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.000000000000000000000000000000000000000000000000001678 200.0
XH2_k127_283365_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 473.0
XH2_k127_283365_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000000000000000000001699 158.0
XH2_k127_283365_2 GYD domain - - - 0.00000000000000000000000000000006063 127.0
XH2_k127_283365_3 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs - - - 0.00000000000000003334 89.0
XH2_k127_2897838_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.72e-213 686.0
XH2_k127_2897838_1 methylthiotransferase activity K15865 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 318.0
XH2_k127_2897838_10 ThiS family K03636 - - 0.000003005 54.0
XH2_k127_2897838_2 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003278 273.0
XH2_k127_2897838_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000003606 151.0
XH2_k127_2897838_4 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000001797 129.0
XH2_k127_2897838_5 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000001784 95.0
XH2_k127_2897838_6 Pfam:DUF59 - - - 0.00000000000000001965 85.0
XH2_k127_2897838_7 pfam nmd3 K07562 - - 0.0000000000000006909 90.0
XH2_k127_2897838_8 IMP dehydrogenase activity - - - 0.0000000000003626 76.0
XH2_k127_2897838_9 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000003092 56.0
XH2_k127_2961285_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 5.678e-211 682.0
XH2_k127_2961285_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 289.0
XH2_k127_2961285_2 Peptidase dimerisation domain K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000434 284.0
XH2_k127_2961285_3 PFAM Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000002026 171.0
XH2_k127_2961285_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000002928 156.0
XH2_k127_2961285_5 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000005019 141.0
XH2_k127_2961285_6 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000001676 102.0
XH2_k127_2961285_7 CoA binding domain K01905 - 6.2.1.13 0.00000000002354 65.0
XH2_k127_2961285_8 - - - - 0.00000002616 59.0
XH2_k127_2961285_9 cobalamin synthesis CobW domain protein K02234 - - 0.00001723 51.0
XH2_k127_301494_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 557.0
XH2_k127_301494_1 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 318.0
XH2_k127_301494_10 4Fe-4S dicluster domain - - - 0.000000000000000000000000000005656 126.0
XH2_k127_301494_11 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000001335 116.0
XH2_k127_301494_12 Uncharacterised ArCR, COG2043 - - - 0.000000000000000003197 93.0
XH2_k127_301494_13 Mo-molybdopterin cofactor metabolic process K03753 - - 0.0000103 53.0
XH2_k127_301494_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 306.0
XH2_k127_301494_3 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001072 272.0
XH2_k127_301494_4 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001973 299.0
XH2_k127_301494_5 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.000000000000000000000000000000000000000000000000000000000000000000002197 253.0
XH2_k127_301494_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000004803 242.0
XH2_k127_301494_7 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000001235 220.0
XH2_k127_301494_8 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000004251 211.0
XH2_k127_301494_9 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K14084 - - 0.0000000000000000000000000000000000000000000000000000257 195.0
XH2_k127_3050637_0 - - - - 0.0000000000000006601 84.0
XH2_k127_3050637_1 Tetratricopeptide repeat - - - 0.000006164 56.0
XH2_k127_3066694_0 AAA-like domain K06915 - - 0.0000000000000000000000000002489 130.0
XH2_k127_3068252_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
XH2_k127_3068252_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003939 258.0
XH2_k127_3068252_2 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000003753 209.0
XH2_k127_3068252_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000001043 199.0
XH2_k127_3068252_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K08698,K08699 - - 0.00000000000000000000000000000000000001043 156.0
XH2_k127_3068252_5 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000002613 136.0
XH2_k127_3093234_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000002493 224.0
XH2_k127_3093234_1 Methionine synthase B12-binding module cap domain protein K16179 - - 0.0000000000000000000000000000000000000000000000000000002626 201.0
XH2_k127_3093234_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000899 188.0
XH2_k127_3093234_3 LUD domain - - - 0.0000000000000000000000000000000000000000000000003006 183.0
XH2_k127_3093234_4 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000001649 163.0
XH2_k127_3093234_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000001456 167.0
XH2_k127_3093234_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000007625 139.0
XH2_k127_3093234_7 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000002543 146.0
XH2_k127_3093234_8 PIN domain of ribonuclease K07060 - - 0.0000000000000000000001186 104.0
XH2_k127_3093234_9 PFAM 4Fe-4S binding domain K00338 - 1.6.5.3 0.000005947 51.0
XH2_k127_3109846_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000449 244.0
XH2_k127_3109846_1 Peptide methionine sulfoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000155 219.0
XH2_k127_3109846_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000005295 202.0
XH2_k127_3109846_3 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000207 164.0
XH2_k127_3109846_5 Thermophilic metalloprotease (M29) - - - 0.00000000000000006849 93.0
XH2_k127_3122141_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 397.0
XH2_k127_3122141_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 391.0
XH2_k127_3201950_0 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 431.0
XH2_k127_3201950_1 COG0306 Phosphate sulphate permeases K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000511 278.0
XH2_k127_3201950_2 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000008474 214.0
XH2_k127_3201950_3 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000004529 192.0
XH2_k127_3201950_4 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000004317 148.0
XH2_k127_3201950_5 PFAM multiple antibiotic resistance (MarC)-related K05595 - - 0.0000000000000000000000000000000000006963 147.0
XH2_k127_3201950_6 PFAM Putitive phosphate transport regulator K07220 - - 0.0000000000000000000000000000006819 130.0
XH2_k127_3211054_0 NAD-dependent epimerase dehydratase K01784,K03274 - 5.1.3.2,5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001935 259.0
XH2_k127_3211054_1 PFAM NAD-dependent epimerase dehydratase K01784,K08678 - 4.1.1.35,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000008466 255.0
XH2_k127_3211054_2 oxidoreductase activity - - - 0.00000000000000000002342 106.0
XH2_k127_3212773_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 508.0
XH2_k127_3212773_1 ABC-type cobalt transport system ATPase component K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000659 271.0
XH2_k127_3212773_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
XH2_k127_3212773_3 ABC-type cobalt transport system, permease K16785 - - 0.000000000000000000000000000000004321 138.0
XH2_k127_3212773_4 ATP-binding protein K16786 - - 0.000000000005175 69.0
XH2_k127_3254023_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 359.0
XH2_k127_3254023_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000007634 64.0
XH2_k127_3254023_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.000000998 58.0
XH2_k127_3274041_0 Methyltransferase MtaA K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 337.0
XH2_k127_3274041_1 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 335.0
XH2_k127_3274041_2 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family - - - 0.0000000000000000000000000000000000000000000000000000000001546 210.0
XH2_k127_3274041_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000007289 117.0
XH2_k127_3274041_4 - - - - 0.00000000000002704 76.0
XH2_k127_3274041_5 pfam yhs - - - 0.0000000003577 60.0
XH2_k127_3274041_6 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000005698 59.0
XH2_k127_3297413_0 PFAM transposase mutator type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 559.0
XH2_k127_3297413_1 PFAM flavin reductase domain protein FMN-binding - - - 0.00000000000000000000000000000000000000000000647 166.0
XH2_k127_3297413_2 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000008566 63.0
XH2_k127_3431764_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 448.0
XH2_k127_3431764_1 Carbon-nitrogen hydrolase K11206 - - 0.000000000000000000000000000000000000000000000000000000007251 211.0
XH2_k127_3431764_2 Trm112p-like protein - - - 0.00000000000000000000004257 102.0
XH2_k127_3431764_3 chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils - - - 0.00000000002781 64.0
XH2_k127_3431764_4 Ferritin-like domain K03594 - 1.16.3.1 0.00002848 49.0
XH2_k127_3434421_0 helicase activity - - - 1.306e-288 906.0
XH2_k127_3434421_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 464.0
XH2_k127_3434421_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000003103 121.0
XH2_k127_3434421_12 Conserved protein implicated in secretion - - - 0.0000000000000000000000001932 113.0
XH2_k127_3434421_13 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000001411 69.0
XH2_k127_3434421_14 Belongs to the ompA family K20276 - - 0.00000000001871 78.0
XH2_k127_3434421_15 AMP binding K03499,K06149 - - 0.00000000011 68.0
XH2_k127_3434421_16 - - - - 0.00000003274 62.0
XH2_k127_3434421_17 domain, Protein K01200,K01226,K20276 - 3.2.1.41,3.2.1.93 0.000246 53.0
XH2_k127_3434421_18 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0005093 50.0
XH2_k127_3434421_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 331.0
XH2_k127_3434421_3 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000001009 204.0
XH2_k127_3434421_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000001689 199.0
XH2_k127_3434421_5 COG0306 Phosphate sulphate permeases K03306 - - 0.00000000000000000000000000000000000000000000000001219 188.0
XH2_k127_3434421_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000001481 166.0
XH2_k127_3434421_7 PFAM Radical SAM - - - 0.000000000000000000000000000000000003224 150.0
XH2_k127_3434421_8 - - - - 0.0000000000000000000000000000001748 142.0
XH2_k127_3434421_9 Transcriptional regulator K07722 - - 0.000000000000000000000000001112 116.0
XH2_k127_3445519_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000001719 216.0
XH2_k127_3445519_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000001738 104.0
XH2_k127_3445519_2 Subtilase family K13274,K14645 - - 0.000000004349 67.0
XH2_k127_3445519_3 Flavodoxin domain - - - 0.00001094 49.0
XH2_k127_3505425_0 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000003609 227.0
XH2_k127_3505425_1 - - - - 0.0000000000000000002854 100.0
XH2_k127_3505425_2 Phospholipid methyltransferase - - - 0.000000108 61.0
XH2_k127_3505425_3 Aldo/keto reductase family - - - 0.000002722 53.0
XH2_k127_3505425_4 Bacterial PH domain - - - 0.0004264 51.0
XH2_k127_3522884_0 PFAM ABC transporter related K03529,K06166,K16786,K16787 - 2.7.8.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000249 265.0
XH2_k127_3522884_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
XH2_k127_3522884_2 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000005636 137.0
XH2_k127_3522884_3 binds to the 23S rRNA K02921 - - 0.0000000000000000000002003 99.0
XH2_k127_3522884_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000004507 85.0
XH2_k127_3522884_5 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.0000000001636 63.0
XH2_k127_3522884_6 Probably involved in the biogenesis of the ribosome K14561 - - 0.0000000001653 69.0
XH2_k127_3522884_7 Transcription factor Pcc1 K09741 - - 0.0002708 49.0
XH2_k127_3524934_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 7.109e-198 631.0
XH2_k127_3524934_1 Belongs to the HMG-CoA reductase family K00021,K00054 - 1.1.1.34,1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 452.0
XH2_k127_3524934_10 PFAM metal-dependent phosphohydrolase HD sub domain K07023 - - 0.000000000000000000000169 105.0
XH2_k127_3524934_11 defense response to virus - - - 0.00000000000000000006548 91.0
XH2_k127_3524934_12 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.000000000000001094 88.0
XH2_k127_3524934_13 integral membrane protein K07027 - - 0.00000000000003349 84.0
XH2_k127_3524934_14 PFAM Putitive phosphate transport regulator K07220 - - 0.000000005107 66.0
XH2_k127_3524934_15 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.000000005908 64.0
XH2_k127_3524934_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000002746 56.0
XH2_k127_3524934_17 Methyl-coenzyme M reductase K03422 - - 0.00000509 53.0
XH2_k127_3524934_18 PFAM GCN5-related N-acetyltransferase - - - 0.0001562 45.0
XH2_k127_3524934_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 335.0
XH2_k127_3524934_3 methanogenesis marker protein 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 300.0
XH2_k127_3524934_4 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003999 292.0
XH2_k127_3524934_5 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000003354 248.0
XH2_k127_3524934_6 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.000000000000000000000000000000000000000000000000000000000000000000002512 242.0
XH2_k127_3524934_7 Methanogenesis marker protein 5 - - - 0.0000000000000000000000000000000000000000000000000000001206 198.0
XH2_k127_3524934_8 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000005542 163.0
XH2_k127_3524934_9 ATPases associated with a variety of cellular activities K00400 - - 0.0000000000000000000000000000000000002225 149.0
XH2_k127_3558980_0 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 419.0
XH2_k127_3558980_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000207 130.0
XH2_k127_3558980_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000001491 79.0
XH2_k127_360143_0 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 454.0
XH2_k127_360143_1 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 376.0
XH2_k127_360143_2 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000002472 145.0
XH2_k127_3636966_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 517.0
XH2_k127_3636966_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 471.0
XH2_k127_3636966_10 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000004714 186.0
XH2_k127_3636966_11 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000000001245 186.0
XH2_k127_3636966_12 conserved protein implicated in secretion - - - 0.00000000000000000157 95.0
XH2_k127_3636966_13 PFAM transcriptional regulator PadR family protein - - - 0.00000000000002181 80.0
XH2_k127_3636966_14 lysine biosynthesis protein LysW K05826 - - 0.00000000001245 66.0
XH2_k127_3636966_15 COGs COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase K05710 - - 0.0000000004605 66.0
XH2_k127_3636966_16 Transcriptional regulator - - - 0.000000002035 70.0
XH2_k127_3636966_17 - - - - 0.0008007 44.0
XH2_k127_3636966_2 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 447.0
XH2_k127_3636966_3 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 389.0
XH2_k127_3636966_4 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 376.0
XH2_k127_3636966_5 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 366.0
XH2_k127_3636966_6 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 333.0
XH2_k127_3636966_7 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 310.0
XH2_k127_3636966_8 phosphoesterase RecJ domain protein K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000001577 235.0
XH2_k127_3636966_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000006495 220.0
XH2_k127_3663829_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 359.0
XH2_k127_3663829_1 Pantothenate synthetase K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 293.0
XH2_k127_3663829_2 HELICc2 K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000006343 259.0
XH2_k127_3663829_3 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000002809 162.0
XH2_k127_3663829_4 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000001348 132.0
XH2_k127_3663829_5 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000004118 99.0
XH2_k127_3663829_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000004277 88.0
XH2_k127_3663829_7 - - - - 0.000002371 57.0
XH2_k127_3678001_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 501.0
XH2_k127_3678001_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 407.0
XH2_k127_3678001_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 344.0
XH2_k127_3678001_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000003431 169.0
XH2_k127_3678001_4 - - - - 0.0000000000000732 81.0
XH2_k127_3678001_5 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000001039 68.0
XH2_k127_3678101_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 344.0
XH2_k127_3678101_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001762 268.0
XH2_k127_3678101_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000003105 192.0
XH2_k127_3678101_3 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000005315 109.0
XH2_k127_3678101_4 DGC domain - - - 0.000000000000000005186 88.0
XH2_k127_3678101_5 - K00960 - 2.7.7.6 0.00000000000004329 74.0
XH2_k127_3678101_6 PFAM GCN5-related N-acetyltransferase - - - 0.000000000364 70.0
XH2_k127_3682476_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.379e-306 953.0
XH2_k127_3682476_1 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 6.793e-253 790.0
XH2_k127_3682476_10 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000706 270.0
XH2_k127_3682476_11 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003477 269.0
XH2_k127_3682476_12 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
XH2_k127_3682476_13 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000007332 222.0
XH2_k127_3682476_14 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000005842 193.0
XH2_k127_3682476_15 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000005046 177.0
XH2_k127_3682476_16 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.000000000000000000000000000000000000001053 160.0
XH2_k127_3682476_17 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000001106 148.0
XH2_k127_3682476_18 Protein of unknown function (DUF483) - - - 0.0000000000000000000000000000001156 133.0
XH2_k127_3682476_19 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000002205 106.0
XH2_k127_3682476_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 543.0
XH2_k127_3682476_20 transcriptional regulator, XRE family - - - 0.0000000000000000000000327 106.0
XH2_k127_3682476_21 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000001355 96.0
XH2_k127_3682476_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000003362 89.0
XH2_k127_3682476_23 - - - - 0.00000000000000007786 89.0
XH2_k127_3682476_24 PFAM Haloacid dehalogenase-like hydrolase K17686 - 3.6.3.54 0.0000000000000008227 85.0
XH2_k127_3682476_25 - - - - 0.000000195 59.0
XH2_k127_3682476_26 Peptidase S24-like K13280 - 3.4.21.89 0.000004273 57.0
XH2_k127_3682476_3 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 527.0
XH2_k127_3682476_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 529.0
XH2_k127_3682476_5 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 494.0
XH2_k127_3682476_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 467.0
XH2_k127_3682476_7 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 370.0
XH2_k127_3682476_8 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008706 367.0
XH2_k127_3682476_9 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 323.0
XH2_k127_3751261_0 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004022 265.0
XH2_k127_3751261_1 - - - - 0.00000000000000000006211 99.0
XH2_k127_3751261_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000003713 93.0
XH2_k127_3829621_0 PFAM beta-lactamase domain protein K07041 - - 7.856e-225 715.0
XH2_k127_3829621_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
XH2_k127_3829621_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000005087 192.0
XH2_k127_3829621_3 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002589 129.0
XH2_k127_3829621_4 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000001121 98.0
XH2_k127_3829621_5 Belongs to the UPF0179 family K09730 - - 0.00000000000000953 79.0
XH2_k127_3829621_6 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000004339 75.0
XH2_k127_3902525_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 527.0
XH2_k127_3902525_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 523.0
XH2_k127_3902525_2 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 521.0
XH2_k127_3902525_3 PFAM peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 334.0
XH2_k127_3902525_4 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008555 259.0
XH2_k127_3902525_5 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000002844 189.0
XH2_k127_3902525_6 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000008964 159.0
XH2_k127_3902525_7 Fumarase C C-terminus K01744 - 4.3.1.1 0.000000000000000000000000005716 115.0
XH2_k127_3902525_8 - - - - 0.00000000000000000001054 101.0
XH2_k127_3969638_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 400.0
XH2_k127_3969638_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
XH2_k127_3969638_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000003443 136.0
XH2_k127_3969638_3 Universal stress protein - - - 0.000000004898 63.0
XH2_k127_3990508_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 362.0
XH2_k127_3990508_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 343.0
XH2_k127_3990508_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000002181 55.0
XH2_k127_4006907_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001576 287.0
XH2_k127_4006907_1 PFAM metal-dependent phosphohydrolase, HD sub domain K17487 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.1.4.56 0.0000000000000000000000000000000000000000001083 167.0
XH2_k127_4051422_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 580.0
XH2_k127_4065081_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759,K22503 - 6.1.1.12,6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 513.0
XH2_k127_4065081_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000003069 245.0
XH2_k127_4065081_10 Cupin domain - - - 0.0000000000000001193 83.0
XH2_k127_4065081_11 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000004715 78.0
XH2_k127_4065081_12 - - - - 0.00000000000678 77.0
XH2_k127_4065081_13 PEP-utilising enzyme, mobile domain - - - 0.000000000007302 70.0
XH2_k127_4065081_14 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000003495 65.0
XH2_k127_4065081_15 - - - - 0.0000008948 51.0
XH2_k127_4065081_2 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000001138 187.0
XH2_k127_4065081_3 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000002237 163.0
XH2_k127_4065081_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000001999 156.0
XH2_k127_4065081_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000000226 141.0
XH2_k127_4065081_6 Transcription elongation factor - - - 0.0000000000000000000000000000005043 128.0
XH2_k127_4065081_7 - - - - 0.00000000000000000000000000000658 130.0
XH2_k127_4065081_8 OsmC-like protein - - - 0.0000000000000000000000001341 112.0
XH2_k127_4065081_9 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000001232 95.0
XH2_k127_4124989_0 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000006559 198.0
XH2_k127_4124989_1 - - - - 0.00000000000000000000000003061 116.0
XH2_k127_4137517_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 430.0
XH2_k127_4137517_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000003577 203.0
XH2_k127_4137517_2 TPP binding domain K01652 - 2.2.1.6 0.0003328 44.0
XH2_k127_4138450_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 307.0
XH2_k127_4138450_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005402 266.0
XH2_k127_4138450_10 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000009148 59.0
XH2_k127_4138450_2 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008726 253.0
XH2_k127_4138450_3 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000002671 161.0
XH2_k127_4138450_4 response regulator, receiver K07669 - - 0.00000000000000000000000000000001531 132.0
XH2_k127_4138450_5 - - - - 0.000000000000000000007243 93.0
XH2_k127_4138450_6 COG1522 Transcriptional regulators - - - 0.0000000000000000002417 89.0
XH2_k127_4138450_8 - - - - 0.0000000003455 64.0
XH2_k127_4209006_0 PFAM ABC transporter related K00400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 565.0
XH2_k127_4209006_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 505.0
XH2_k127_4209006_10 Transcriptional regulator K07108,K22206 - - 0.00000004452 61.0
XH2_k127_4209006_11 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.0000002242 56.0
XH2_k127_4209006_2 Phosphomethylpyrimidine kinase K00941,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
XH2_k127_4209006_3 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 387.0
XH2_k127_4209006_4 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 311.0
XH2_k127_4209006_5 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000004102 210.0
XH2_k127_4209006_6 PFAM TfuA domain protein, core - - - 0.0000000000000000000000000000000000000000000000000003058 192.0
XH2_k127_4209006_7 Transcriptional regulator K22206 - - 0.00000000000000000000000000000000000002453 156.0
XH2_k127_4209006_8 - K02339 - 2.7.7.7 0.00000000000686 72.0
XH2_k127_4209006_9 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000002709 57.0
XH2_k127_4390092_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 430.0
XH2_k127_4390092_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 413.0
XH2_k127_4390092_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 364.0
XH2_k127_4390092_3 Helix-turn-helix domain K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005236 264.0
XH2_k127_4390092_4 PFAM PUA domain containing protein K07398 - - 0.0000000000000000000000000000000000000009486 152.0
XH2_k127_4390092_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000004461 141.0
XH2_k127_4390092_6 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000002226 80.0
XH2_k127_4472256_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 550.0
XH2_k127_4472256_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 346.0
XH2_k127_4472256_10 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000004015 105.0
XH2_k127_4472256_11 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.00000000000000000004659 98.0
XH2_k127_4472256_13 Domain of unknown function (DUF296) K06934 - - 0.0000001206 59.0
XH2_k127_4472256_14 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0002294 44.0
XH2_k127_4472256_2 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002971 276.0
XH2_k127_4472256_3 glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000007808 241.0
XH2_k127_4472256_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000002965 211.0
XH2_k127_4472256_5 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000006534 198.0
XH2_k127_4472256_6 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000002183 192.0
XH2_k127_4472256_7 DNA polymerase beta domain protein region K07073 - - 0.0000000000000000000000000000000000000000000000007978 183.0
XH2_k127_4472256_8 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000000000000000000002519 144.0
XH2_k127_4472256_9 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000001201 112.0
XH2_k127_4532200_0 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000004495 254.0
XH2_k127_4532200_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000001928 242.0
XH2_k127_4532200_10 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0008163 48.0
XH2_k127_4532200_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000007906 229.0
XH2_k127_4532200_3 TIGRFAM arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000004229 215.0
XH2_k127_4532200_4 PFAM BioY protein K03523 - - 0.00000000000000000000000000002451 123.0
XH2_k127_4532200_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000001146 109.0
XH2_k127_4532200_6 Conserved protein implicated in secretion - - - 0.0000000000000001329 87.0
XH2_k127_4532200_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000006837 76.0
XH2_k127_4532200_8 Uncharacterized conserved protein (DUF2299) - - - 0.00000000000001908 79.0
XH2_k127_4539947_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.503e-202 646.0
XH2_k127_4576134_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 332.0
XH2_k127_4576134_1 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003791 269.0
XH2_k127_4576134_10 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000005845 66.0
XH2_k127_4576134_11 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00002134 51.0
XH2_k127_4576134_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0008562 43.0
XH2_k127_4576134_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006133 261.0
XH2_k127_4576134_3 Binds the lower part of the 30S subunit head K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004309 211.0
XH2_k127_4576134_4 Putative RNA methyltransferase K09142 - - 0.0000000000000000000000000000000000000000000000000003681 194.0
XH2_k127_4576134_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000001028 183.0
XH2_k127_4576134_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000005414 148.0
XH2_k127_4576134_7 - - - - 0.0000000000000000000000000000000001769 140.0
XH2_k127_4576134_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000004831 128.0
XH2_k127_4576134_9 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000222 70.0
XH2_k127_4583815_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000008809 196.0
XH2_k127_4583815_1 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000002462 177.0
XH2_k127_4687367_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 6.199e-245 781.0
XH2_k127_4687367_1 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000007664 59.0
XH2_k127_4713301_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 433.0
XH2_k127_4713301_1 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000002684 136.0
XH2_k127_4749669_0 4'-phosphopantetheinyl transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000001096 139.0
XH2_k127_4749669_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000001732 137.0
XH2_k127_4749669_2 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000004386 55.0
XH2_k127_4909577_0 GTPase of K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 381.0
XH2_k127_4909577_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000004563 160.0
XH2_k127_4909577_2 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.00000000000008035 75.0
XH2_k127_4970484_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 295.0
XH2_k127_4970484_1 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008811 202.0
XH2_k127_4970484_10 RNA polymerase Rpb3/Rpb11 dimerisation domain K03008 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0006139,GO:0006351,GO:0006353,GO:0006366,GO:0006369,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016591,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 - 0.000000000000008505 77.0
XH2_k127_4970484_11 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000001336 57.0
XH2_k127_4970484_2 Diphthamide K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000008556 205.0
XH2_k127_4970484_3 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000004808 196.0
XH2_k127_4970484_4 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000374 180.0
XH2_k127_4970484_5 Conserved hypothetical protein 95 K07579 - - 0.00000000000000000000000000000000000000000001592 169.0
XH2_k127_4970484_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000008649 125.0
XH2_k127_4970484_7 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001038 117.0
XH2_k127_4970484_8 Lysine methyltransferase K02493 - 2.1.1.297 0.0000000000000000000000000002926 124.0
XH2_k127_4970484_9 Ribonuclease III - - - 0.0000000000000000002714 93.0
XH2_k127_4999612_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 335.0
XH2_k127_4999612_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 327.0
XH2_k127_4999612_2 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 308.0
XH2_k127_4999612_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000006471 200.0
XH2_k127_4999612_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000001602 151.0
XH2_k127_4999612_5 orotidine-5'-phosphate decarboxylase activity K01591 - 4.1.1.23 0.000000000000000000000000002003 115.0
XH2_k127_5032284_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 556.0
XH2_k127_5032284_1 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.0000205 50.0
XH2_k127_5185027_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 385.0
XH2_k127_5185027_1 - - - - 0.000000000000000000000000000000000000006155 159.0
XH2_k127_5185027_2 - - - - 0.0000000000000000000000000000005555 129.0
XH2_k127_5185027_3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000009587 73.0
XH2_k127_5186493_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 581.0
XH2_k127_5186493_1 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 551.0
XH2_k127_5186493_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 327.0
XH2_k127_5186493_3 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 331.0
XH2_k127_5186493_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 298.0
XH2_k127_5186493_5 Transglutaminase-like superfamily - - - 0.00000000000008396 82.0
XH2_k127_5186493_6 - - - - 0.00006187 52.0
XH2_k127_5196541_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000527 143.0
XH2_k127_5196541_1 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000009727 132.0
XH2_k127_5196541_2 ECF-type riboflavin transporter, S component K16927 - - 0.0000000000000000000003424 104.0
XH2_k127_5196541_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000001081 74.0
XH2_k127_5238393_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 450.0
XH2_k127_5257092_0 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 4.937e-199 642.0
XH2_k127_5257092_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 466.0
XH2_k127_5257092_10 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
XH2_k127_5257092_11 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000394 234.0
XH2_k127_5257092_12 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000002556 184.0
XH2_k127_5257092_13 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0000000000000000000000000000000000000000000000002844 189.0
XH2_k127_5257092_14 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000001153 170.0
XH2_k127_5257092_15 membrane - - - 0.000000000000000000000000000000000000009305 155.0
XH2_k127_5257092_16 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000001172 148.0
XH2_k127_5257092_17 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000006367 143.0
XH2_k127_5257092_18 ECF-type riboflavin transporter, S component - - - 0.0000000000000000000000000000005783 136.0
XH2_k127_5257092_19 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000008546 109.0
XH2_k127_5257092_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 379.0
XH2_k127_5257092_20 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.00000000000000000000109 104.0
XH2_k127_5257092_21 Molybdopterin guanine dinucleotide synthesis protein B K03753 - - 0.00000000000000003792 87.0
XH2_k127_5257092_22 helicase superfamily c-terminal domain - - - 0.00000000000001764 85.0
XH2_k127_5257092_23 regulatory protein, arsR - - - 0.000000000001576 77.0
XH2_k127_5257092_24 THUMP K06963 - - 0.00000007123 61.0
XH2_k127_5257092_25 GINS complex protein K09723 - - 0.0000001223 60.0
XH2_k127_5257092_26 PFAM Major Facilitator Superfamily K08223 - - 0.0000002526 63.0
XH2_k127_5257092_27 DEAD DEAH box helicase domain protein K10896 - - 0.0000009142 56.0
XH2_k127_5257092_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 371.0
XH2_k127_5257092_4 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 351.0
XH2_k127_5257092_5 PFAM elongation factor Tu domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 333.0
XH2_k127_5257092_6 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 323.0
XH2_k127_5257092_7 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 306.0
XH2_k127_5257092_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
XH2_k127_5257092_9 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 271.0
XH2_k127_5319619_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 530.0
XH2_k127_5319619_1 deoxyhypusine monooxygenase activity - - - 0.000000000000000001267 89.0
XH2_k127_5319619_2 Phospholipid methyltransferase - - - 0.000000000007495 78.0
XH2_k127_5327210_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007476 258.0
XH2_k127_5327210_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000002884 194.0
XH2_k127_5327210_2 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000008627 176.0
XH2_k127_5327210_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000000115 118.0
XH2_k127_5374276_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 469.0
XH2_k127_5374276_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002011 211.0
XH2_k127_5374276_2 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.0000000000000000000000007126 112.0
XH2_k127_5374276_3 MFS_1 like family - - - 0.00000000000000006282 93.0
XH2_k127_5436257_0 Diaminopropionate ammonia-lyase K01751 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007497 284.0
XH2_k127_5436257_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000001673 137.0
XH2_k127_5436257_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000002116 110.0
XH2_k127_543781_0 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
XH2_k127_543781_1 Protein disulfide isomerase K01829,K09584 - 5.3.4.1 0.00000003705 60.0
XH2_k127_543781_2 SMART Elongator protein 3 MiaB NifB - - - 0.000003246 57.0
XH2_k127_543781_3 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.000003397 60.0
XH2_k127_5451848_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 444.0
XH2_k127_5451848_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 300.0
XH2_k127_5454673_0 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000006275 244.0
XH2_k127_5454673_1 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000267 209.0
XH2_k127_5454673_2 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000003047 182.0
XH2_k127_5457915_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 376.0
XH2_k127_5457915_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
XH2_k127_5457915_2 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000009122 158.0
XH2_k127_5561828_0 Sodium:neurotransmitter symporter family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 438.0
XH2_k127_5561828_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002179 271.0
XH2_k127_5561828_10 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000006447 105.0
XH2_k127_5561828_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000002207 96.0
XH2_k127_5561828_2 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000001182 235.0
XH2_k127_5561828_3 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000002857 216.0
XH2_k127_5561828_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000001861 212.0
XH2_k127_5561828_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000023 186.0
XH2_k127_5561828_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000002443 167.0
XH2_k127_5561828_7 PFAM methyltransferase small - - - 0.00000000000000000000000000000000001487 139.0
XH2_k127_5561828_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000008774 138.0
XH2_k127_5561828_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002894 124.0
XH2_k127_5646997_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.309e-204 646.0
XH2_k127_5646997_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 460.0
XH2_k127_5646997_2 DUF460 domain containing protein K09150 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001485 281.0
XH2_k127_5646997_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000009296 100.0
XH2_k127_5646997_4 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000007397 77.0
XH2_k127_5646997_5 Methyltransferase type 11 - - - 0.00000000000107 75.0
XH2_k127_5646997_6 ThiS family K03636 - - 0.000000001551 61.0
XH2_k127_5705485_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.612e-201 641.0
XH2_k127_5705485_1 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 539.0
XH2_k127_5705485_10 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000006801 224.0
XH2_k127_5705485_11 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000971 225.0
XH2_k127_5705485_12 with the TIM-barrel fold K07051 - - 0.000000000000000000000000000000000000000001125 167.0
XH2_k127_5705485_13 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.00000000000000000000000000000000000000005088 156.0
XH2_k127_5705485_14 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000186 148.0
XH2_k127_5705485_15 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000004328 119.0
XH2_k127_5705485_16 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091,K06019 - 3.1.3.18,3.6.1.1 0.00000000000000000000000001941 117.0
XH2_k127_5705485_17 Methionine synthase B12-binding module cap domain protein K00548,K14081,K16179 - 2.1.1.13 0.000000000000000000000000505 112.0
XH2_k127_5705485_18 Cyclophilin-like K09143 - - 0.00000000000000000000002326 103.0
XH2_k127_5705485_19 - - - - 0.00000000000000001083 87.0
XH2_k127_5705485_2 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 441.0
XH2_k127_5705485_20 DNA-directed RNA polymerases I, II, and III subunit K03014 GO:0000003,GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0005666,GO:0005730,GO:0005736,GO:0008150,GO:0016591,GO:0030880,GO:0031974,GO:0031981,GO:0032502,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0055029,GO:0061695,GO:0070013,GO:1902494,GO:1990234 - 0.0000000000002439 77.0
XH2_k127_5705485_21 Transcriptional regulator, TrmB - - - 0.0000000000002449 79.0
XH2_k127_5705485_22 Mannose-6-phosphate isomerase K01485 - 3.5.4.1 0.0000000003705 66.0
XH2_k127_5705485_23 S25 ribosomal protein K02975 - - 0.00000009437 57.0
XH2_k127_5705485_24 Belongs to the UPF0237 family K07166 - - 0.000001625 53.0
XH2_k127_5705485_3 PFAM amidohydrolase K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 449.0
XH2_k127_5705485_4 TIGRFAM dihydroorotate dehydrogenase family protein K17723 - 1.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 421.0
XH2_k127_5705485_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 377.0
XH2_k127_5705485_6 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 354.0
XH2_k127_5705485_7 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 327.0
XH2_k127_5705485_8 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001724 260.0
XH2_k127_5705485_9 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000008709 229.0
XH2_k127_5733065_0 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 9.443e-199 630.0
XH2_k127_5733065_1 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000001232 168.0
XH2_k127_5733065_2 beta-lactamase domain protein - - - 0.000000000000000000000000005006 120.0
XH2_k127_5733065_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000006492 109.0
XH2_k127_5739211_0 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001878 244.0
XH2_k127_5739211_1 PFAM 4-vinyl reductase, 4VR K07013 - - 0.00000001559 65.0
XH2_k127_5852024_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 386.0
XH2_k127_5852024_1 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000000000000000000000000000000000000000000000000000006061 194.0
XH2_k127_5852024_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000003848 107.0
XH2_k127_5852024_3 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 0.0000000000000000000009614 98.0
XH2_k127_5956496_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 627.0
XH2_k127_5956496_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000002154 231.0
XH2_k127_5956496_2 GPR1 FUN34 yaaH family protein K07034 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006835,GO:0006846,GO:0006855,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015123,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015355,GO:0015360,GO:0015672,GO:0015711,GO:0015718,GO:0015740,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034220,GO:0035433,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0043893,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071422,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000002749 168.0
XH2_k127_5956496_3 Phosphate uptake regulator - - - 0.00000000000000000000000000000000001009 149.0
XH2_k127_597530_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 445.0
XH2_k127_597530_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 339.0
XH2_k127_597530_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 341.0
XH2_k127_597530_3 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000342 289.0
XH2_k127_597530_4 PUCC protein - - - 0.0000000000000000000000000000000000000000000000000000000003908 217.0
XH2_k127_597530_5 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000000004495 165.0
XH2_k127_597530_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000001172 141.0
XH2_k127_597530_7 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000331 109.0
XH2_k127_597530_8 Putative Phosphatase - - - 0.00000000000000000000003074 107.0
XH2_k127_5994185_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 583.0
XH2_k127_5994185_1 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000003038 241.0
XH2_k127_5994185_2 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000013 218.0
XH2_k127_5994185_3 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000004889 187.0
XH2_k127_6006417_0 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 402.0
XH2_k127_6006417_1 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.00000000000000000000000000000000000003123 156.0
XH2_k127_6006417_2 - - - - 0.000000000000000000000002111 108.0
XH2_k127_6006417_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.0000000000000000008532 95.0
XH2_k127_6044221_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 379.0
XH2_k127_6044221_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K00806,K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 289.0
XH2_k127_6044221_10 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000000000000000000000000000000000000000003887 180.0
XH2_k127_6044221_11 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000009653 160.0
XH2_k127_6044221_12 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000001019 160.0
XH2_k127_6044221_13 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000009505 154.0
XH2_k127_6044221_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000009498 120.0
XH2_k127_6044221_15 Belongs to the UPF0201 family K09736 - - 0.00000000000000000000001013 105.0
XH2_k127_6044221_16 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000008315 98.0
XH2_k127_6044221_17 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000005166 83.0
XH2_k127_6044221_18 archaeal coiled-coil protein - - - 0.000000000000008989 85.0
XH2_k127_6044221_19 - - - - 0.0000000000000256 74.0
XH2_k127_6044221_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000003472 262.0
XH2_k127_6044221_3 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000004126 256.0
XH2_k127_6044221_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000198 242.0
XH2_k127_6044221_5 ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000003698 216.0
XH2_k127_6044221_6 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000009122 220.0
XH2_k127_6044221_7 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000005314 199.0
XH2_k127_6044221_8 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000121 199.0
XH2_k127_6044221_9 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000006345 193.0
XH2_k127_6052240_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 398.0
XH2_k127_6052240_1 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 316.0
XH2_k127_6052240_2 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 308.0
XH2_k127_6052240_3 COG1100 GTPase SAR1 and related small G K06883 - - 0.0000000000000000000000000000000000000000000001068 178.0
XH2_k127_6052240_4 ferric iron binding K02380 - - 0.000729 44.0
XH2_k127_6068168_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1014.0
XH2_k127_6068168_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 388.0
XH2_k127_6068168_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
XH2_k127_6068168_3 N2,N2-dimethylguanosine tRNA methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000003723 227.0
XH2_k127_6068168_4 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000002146 106.0
XH2_k127_6068168_5 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000001964 59.0
XH2_k127_6095868_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.17e-281 884.0
XH2_k127_6095868_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000003212 199.0
XH2_k127_6095868_2 membrane - - - 0.000000000000000000000000000008599 128.0
XH2_k127_6095868_3 PFAM GH3 auxin-responsive promoter - - - 0.00000000000000000001255 104.0
XH2_k127_6095868_4 Hemerythrin HHE cation binding domain - - - 0.0000000023 65.0
XH2_k127_6124208_0 ABC-type tungstate transport system, permease component K05772 - - 0.000000000000000000000000000000000000000000000000000000000000003928 228.0
XH2_k127_6124208_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000009651 202.0
XH2_k127_6124208_2 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000001343 196.0
XH2_k127_6124208_3 transcriptional regulator, ModE family K02019 - - 0.0000000000002009 81.0
XH2_k127_619955_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 382.0
XH2_k127_619955_1 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000001084 229.0
XH2_k127_619955_2 HELICc2 K10844 - 3.6.4.12 0.0000000000000000000000000000000000002672 147.0
XH2_k127_6205140_0 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000001316 158.0
XH2_k127_6205140_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000005006 78.0
XH2_k127_6205140_3 PFAM major facilitator superfamily MFS_1 - - - 0.0000001244 54.0
XH2_k127_6239517_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 571.0
XH2_k127_624644_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 493.0
XH2_k127_624644_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000001732 207.0
XH2_k127_624644_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000004473 207.0
XH2_k127_624644_3 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.00000000000001561 82.0
XH2_k127_6474621_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008263 279.0
XH2_k127_6474621_1 hydrogenase maturation protease K03605 - - 0.0000000000000000000001355 104.0
XH2_k127_6474621_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000001549 65.0
XH2_k127_6518523_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 402.0
XH2_k127_6518523_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000001461 220.0
XH2_k127_6518523_10 PhoPQ-activated pathogenicity-related protein - - - 0.00005395 55.0
XH2_k127_6518523_2 Fe-S cluster K04488 - - 0.0000000000000000000000000000000000000000000000000000000001733 205.0
XH2_k127_6518523_3 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000003359 199.0
XH2_k127_6518523_4 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000004045 179.0
XH2_k127_6518523_5 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000000000000000000000000000000008486 166.0
XH2_k127_6518523_6 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000002626 92.0
XH2_k127_6518523_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000007971 100.0
XH2_k127_6518523_8 Transcriptional regulator K07332 - - 0.00000000000000001474 93.0
XH2_k127_6518523_9 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000001041 89.0
XH2_k127_6561178_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000506 191.0
XH2_k127_6561178_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000004045 179.0
XH2_k127_6694276_0 Homocitrate synthase K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 481.0
XH2_k127_6694276_1 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000002009 217.0
XH2_k127_6694276_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000000000001618 173.0
XH2_k127_6724357_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 327.0
XH2_k127_6724357_1 Amino acid synthesis - - - 0.000000000000000000000000000000000002276 142.0
XH2_k127_6724357_2 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000001163 141.0
XH2_k127_6724357_3 QueT transporter - - - 0.000000000000003763 82.0
XH2_k127_6724357_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000227 58.0
XH2_k127_7024942_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1407.0
XH2_k127_7024942_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1137.0
XH2_k127_7024942_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 589.0
XH2_k127_7024942_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 411.0
XH2_k127_7024942_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004048 250.0
XH2_k127_7024942_5 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002419 222.0
XH2_k127_7024942_6 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000001751 168.0
XH2_k127_7024942_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000001801 152.0
XH2_k127_7024942_8 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000007153 94.0
XH2_k127_7024942_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000001238 84.0
XH2_k127_708822_0 ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 472.0
XH2_k127_708822_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one- carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 397.0
XH2_k127_708822_2 PFAM beta-lactamase domain protein K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 353.0
XH2_k127_708822_3 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000004689 213.0
XH2_k127_708822_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000005908 199.0
XH2_k127_708822_5 PFAM PAC2 family K06869 - - 0.0000000000000000000000000000000002168 141.0
XH2_k127_708822_6 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000001012 117.0
XH2_k127_708822_7 - - - - 0.000002304 49.0
XH2_k127_708822_8 zinc-ribbon domain - - - 0.00001578 52.0
XH2_k127_708822_9 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0006363 46.0
XH2_k127_7108468_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 8.019e-218 687.0
XH2_k127_7108468_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 591.0
XH2_k127_7108468_10 - - - - 0.000000197 64.0
XH2_k127_7108468_2 III protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 416.0
XH2_k127_7108468_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 358.0
XH2_k127_7108468_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000002038 208.0
XH2_k127_7108468_5 TIGRFAM F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000008297 204.0
XH2_k127_7108468_6 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000007518 169.0
XH2_k127_7108468_7 ASNC family K03718 - - 0.00000000000000000000000000000000000000123 152.0
XH2_k127_7108468_8 Biotin-requiring enzyme - - - 0.000000000000001783 81.0
XH2_k127_7108468_9 type II secretion system K07333 - - 0.0000000008766 63.0
XH2_k127_7118797_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1035.0
XH2_k127_7118797_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 501.0
XH2_k127_7118797_10 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000002376 79.0
XH2_k127_7118797_11 DNA topoisomerase, type IA, central domain protein K03168,K03169 - 5.99.1.2 0.00000000000003169 75.0
XH2_k127_7118797_12 protein conserved in archaea K09723 - - 0.0000979 51.0
XH2_k127_7118797_2 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 331.0
XH2_k127_7118797_3 Oligosaccharyl transferase, STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001105 273.0
XH2_k127_7118797_4 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000004573 222.0
XH2_k127_7118797_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000002452 138.0
XH2_k127_7118797_6 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000003812 115.0
XH2_k127_7118797_7 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000004705 109.0
XH2_k127_7118797_8 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000006384 83.0
XH2_k127_7118797_9 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000008583 81.0
XH2_k127_7292662_0 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000002142 122.0
XH2_k127_7292662_1 - - - - 0.00000000000001408 83.0
XH2_k127_7345757_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002921 276.0
XH2_k127_7345757_1 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000002184 213.0
XH2_k127_7345757_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000001552 156.0
XH2_k127_7345757_3 Winged helix-turn-helix - - - 0.0000000000001459 74.0
XH2_k127_7386763_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 426.0
XH2_k127_7386763_1 PFAM multiple antibiotic resistance (MarC)-related K05595 - - 0.000000000000000000000000000000000000000006342 164.0
XH2_k127_7386763_2 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000000001939 137.0
XH2_k127_7386763_3 NMT1-like family - - - 0.000000000002958 74.0
XH2_k127_7386763_4 HTH DNA binding domain - - - 0.00003153 47.0
XH2_k127_764905_0 - - - - 0.00000000000000000000000000000009136 132.0
XH2_k127_764905_1 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.000000000000000000000000002727 116.0
XH2_k127_7778153_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 5.566e-219 691.0
XH2_k127_7778153_1 PFAM Transcription factor CBF NF-Y - - - 0.0000000000000004671 80.0
XH2_k127_7778153_2 ParB-like nuclease domain - - - 0.0000000000007919 71.0
XH2_k127_7778153_3 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000005337 72.0
XH2_k127_7804919_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 5.26e-223 707.0
XH2_k127_7804919_1 Cupin domain - - - 0.000000000000000000000000000000000006298 140.0
XH2_k127_7941761_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 451.0
XH2_k127_7941761_1 DNA primase K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 413.0
XH2_k127_7941761_10 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 298.0
XH2_k127_7941761_11 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000004656 224.0
XH2_k127_7941761_12 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000001235 193.0
XH2_k127_7941761_13 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000001247 149.0
XH2_k127_7941761_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 2.7.7.3 0.000000000000000000000000000001562 126.0
XH2_k127_7941761_15 PFAM helix-turn-helix domain protein K03627 - - 0.000000000000000000000000005539 116.0
XH2_k127_7941761_16 CBS domain - - - 0.000000000000000000000001839 113.0
XH2_k127_7941761_17 PFAM CBS domain containing protein - - - 0.00000000000000000000002234 105.0
XH2_k127_7941761_18 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000002871 102.0
XH2_k127_7941761_19 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000006689 102.0
XH2_k127_7941761_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 412.0
XH2_k127_7941761_20 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000009096 85.0
XH2_k127_7941761_21 metalloendopeptidase activity - - - 0.000000008064 61.0
XH2_k127_7941761_22 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000007305 55.0
XH2_k127_7941761_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 392.0
XH2_k127_7941761_4 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 380.0
XH2_k127_7941761_5 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 368.0
XH2_k127_7941761_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
XH2_k127_7941761_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 329.0
XH2_k127_7941761_8 DUF1512 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 314.0
XH2_k127_7941761_9 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 308.0
XH2_k127_7987283_0 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 275.0
XH2_k127_7987283_1 - - - - 0.000000002387 62.0
XH2_k127_7987283_2 Protein of unknown function (DUF3795) - - - 0.0001823 50.0
XH2_k127_8122670_0 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 445.0
XH2_k127_8122670_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 413.0
XH2_k127_8132475_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 GO:0003674,GO:0005488,GO:0005515,GO:0042802 6.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 440.0
XH2_k127_8132475_1 hydrogenase expression formation protein K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 355.0
XH2_k127_8132475_10 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000004541 192.0
XH2_k127_8132475_11 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000001095 173.0
XH2_k127_8132475_12 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000004005 149.0
XH2_k127_8132475_13 PFAM Translin K07477 - - 0.00000000000000000000000000000000003265 142.0
XH2_k127_8132475_14 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000004542 138.0
XH2_k127_8132475_15 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000000000000747 134.0
XH2_k127_8132475_16 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.00000000000000000000000000003634 124.0
XH2_k127_8132475_17 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000003777 115.0
XH2_k127_8132475_18 HupF/HypC family K04653 - - 0.00000000000000002025 83.0
XH2_k127_8132475_19 methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000004419 85.0
XH2_k127_8132475_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 346.0
XH2_k127_8132475_20 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.0000000001368 67.0
XH2_k127_8132475_21 Belongs to the UPF0248 family K09715 - - 0.000004447 55.0
XH2_k127_8132475_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 339.0
XH2_k127_8132475_4 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 307.0
XH2_k127_8132475_5 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001433 276.0
XH2_k127_8132475_6 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000007707 231.0
XH2_k127_8132475_7 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000001609 220.0
XH2_k127_8132475_8 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.00000000000000000000000000000000000000000000000000000000002667 218.0
XH2_k127_8132475_9 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000006334 217.0
XH2_k127_8147099_0 PFAM Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006865 283.0
XH2_k127_8147099_2 Trehalose-phosphatase K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000003472 174.0
XH2_k127_8147099_3 PFAM zinc iron permease K07238 - - 0.0000000000000000000000000000000000000005491 157.0
XH2_k127_8147099_4 Glycosyltransferase - - - 0.0000000000000000000000000000000000005209 146.0
XH2_k127_8147099_5 RNA-binding protein contains TRAM domain - - - 0.000000000000000003367 87.0
XH2_k127_8147099_6 chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils - - - 0.00000001832 56.0
XH2_k127_8147099_7 - - - - 0.0000009654 59.0
XH2_k127_8147099_8 Transporter, small conductance mechanosensitive ion channel MscS family protein K03442 - - 0.0000111 56.0
XH2_k127_8147099_9 Domain of unknown function (DUF4184) - - - 0.00004373 53.0
XH2_k127_8178004_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 449.0
XH2_k127_8178004_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000001073 191.0
XH2_k127_8178004_2 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000007809 151.0
XH2_k127_8178004_3 PFAM UDP-glucuronosyl UDP-glucosyltransferase - - - 0.0000000000000000000000007342 117.0
XH2_k127_8178004_4 Permeases of the major facilitator superfamily K08153 - - 0.000000000000000007676 95.0
XH2_k127_8291873_0 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 492.0
XH2_k127_8322199_0 radical SAM domain protein K09711 - - 0.000000000000000000000000000000000000000000000003762 182.0
XH2_k127_8322199_1 TIGRFAM Glutaredoxin-like domain protein - - - 0.00000000000000000000000000000000000151 146.0
XH2_k127_8322199_2 - - - - 0.0000000000000000000000000000000001647 139.0
XH2_k127_8322199_3 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000026 86.0
XH2_k127_8322199_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0002703 51.0
XH2_k127_8434409_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 298.0
XH2_k127_8434409_1 AAA domain, putative AbiEii toxin, Type IV TA system K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000609 274.0
XH2_k127_8434409_2 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000001781 207.0
XH2_k127_8434409_3 - - - - 0.000000000000000000000000000000000001629 145.0
XH2_k127_8434409_4 - - - - 0.000000000000000000000000000001906 128.0
XH2_k127_8434409_5 Belongs to the phosphohexose mutase family - - - 0.00000000000479 67.0
XH2_k127_8508411_0 SMART Elongator protein 3 MiaB NifB K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 485.0
XH2_k127_8508411_1 PFAM Type II IV secretion system protein K06865 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 454.0
XH2_k127_8508411_2 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 343.0
XH2_k127_8508411_3 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000003134 206.0
XH2_k127_8508411_4 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000006294 205.0
XH2_k127_8508411_5 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000000000000000003196 153.0
XH2_k127_8508411_6 acetyl coenzyme A synthetase K01905,K22224 - 6.2.1.13 0.000000000000000003949 85.0
XH2_k127_8508411_7 Belongs to the thioredoxin family K03671 - - 0.0000000000000001592 83.0
XH2_k127_8508411_8 Methyltransferase activity. It is involved in the biological process described with metabolic process K15444 GO:0000049,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051213,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.229 0.00000000000003868 83.0
XH2_k127_8530409_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 437.0
XH2_k127_8530409_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006408 264.0
XH2_k127_8530409_2 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000503 157.0
XH2_k127_8530409_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000001177 144.0
XH2_k127_8530409_4 Permease for cytosine/purines, uracil, thiamine, allantoin K10974 - - 0.00000000000002973 83.0
XH2_k127_8530409_5 heterodisulfide reductase K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0002615 48.0
XH2_k127_8550595_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 353.0
XH2_k127_8550595_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000005427 175.0
XH2_k127_8550595_2 Belongs to the peptidase M48B family K03799 - - 0.000000009225 57.0
XH2_k127_8634438_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 497.0
XH2_k127_8634438_1 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004268 259.0
XH2_k127_8634438_2 PFAM permease K07089 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000004358 188.0
XH2_k127_8634438_4 redox-active disulfide protein 2 - - - 0.0000000003321 64.0
XH2_k127_8634438_5 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0055114 - 0.000000000433 63.0
XH2_k127_8648945_0 protein synthesis factor GTP-binding K03231 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 486.0
XH2_k127_8648945_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000001368 210.0
XH2_k127_8648945_2 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000001391 187.0
XH2_k127_8648945_3 - - - - 0.0000000000000000000000000004576 117.0
XH2_k127_867505_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 347.0
XH2_k127_867505_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000002823 228.0
XH2_k127_867505_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000285 177.0
XH2_k127_867505_3 Belongs to the imidazoleglycerol-phosphate dehydratase family K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000003084 173.0
XH2_k127_867505_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000004879 118.0
XH2_k127_867505_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000002166 103.0
XH2_k127_8687965_0 PFAM ABC transporter related K00400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 308.0
XH2_k127_8687965_1 Domain of unknown function (DUF4445) - - - 0.0000000000000000001051 94.0
XH2_k127_8691914_0 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000003704 254.0
XH2_k127_8691914_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000008106 211.0
XH2_k127_8691914_2 GHMP kinases N terminal domain - - - 0.00000000000000000000000000000000000000000000000000000004981 207.0
XH2_k127_8691914_3 SMART zinc finger, RanBP2-type - - - 0.0000000000000000000000000000000000000000000000000003643 198.0
XH2_k127_8691914_4 Double zinc ribbon - - - 0.0000004588 55.0
XH2_k127_8691914_5 - - - - 0.00000116 61.0
XH2_k127_8691914_6 - - - - 0.00004476 52.0
XH2_k127_8900276_0 symporter activity K11928,K14392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 349.0
XH2_k127_8900276_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002097 224.0
XH2_k127_8900276_2 hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000003255 149.0
XH2_k127_8900276_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000854 153.0
XH2_k127_8900276_4 Nickel-dependent hydrogenase K17993 - 1.12.1.3,1.12.1.5 0.000000000000000000002161 102.0
XH2_k127_8929858_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 462.0
XH2_k127_8929858_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000002953 255.0
XH2_k127_8929858_2 PFAM phosphatidate cytidylyltransferase - - - 0.0000000000000000000007461 102.0
XH2_k127_8929858_3 PFAM Transcription elongation factor Elf1 like - - - 0.000000000000004601 78.0
XH2_k127_8929858_4 regulation of nucleic acid-templated transcription - - - 0.00000000000002494 83.0
XH2_k127_8990506_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 538.0
XH2_k127_8990506_1 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 426.0
XH2_k127_8990506_10 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000004843 70.0
XH2_k127_8990506_11 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000644 49.0
XH2_k127_8990506_12 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0002999 44.0
XH2_k127_8990506_2 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 400.0
XH2_k127_8990506_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 280.0
XH2_k127_8990506_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000002225 255.0
XH2_k127_8990506_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000007594 200.0
XH2_k127_8990506_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000002584 112.0
XH2_k127_8990506_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14091 - - 0.00000000000000000003746 94.0
XH2_k127_8990506_8 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000001389 92.0
XH2_k127_8990506_9 electron transfer activity K05337 - - 0.0000000000002022 72.0
XH2_k127_9035264_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 1.684e-253 810.0
XH2_k127_9035264_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 607.0
XH2_k127_9035264_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 518.0
XH2_k127_9035264_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 489.0
XH2_k127_9035264_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 419.0
XH2_k127_9035264_5 Uncharacterized protein conserved in archaea (DUF2286) - - - 0.0000000000000001112 85.0
XH2_k127_9035264_6 - - - - 0.000000000000002168 88.0
XH2_k127_9035264_7 - - - - 0.00000000000002145 76.0
XH2_k127_9035264_8 - - - - 0.000007298 50.0
XH2_k127_9098730_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 513.0
XH2_k127_9098730_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008997 262.0
XH2_k127_9098730_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000004786 211.0
XH2_k127_9098730_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000002875 190.0
XH2_k127_9098730_4 PFAM UspA domain protein - - - 0.0000000000000106 79.0
XH2_k127_9098730_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000001558 56.0
XH2_k127_9098730_6 - - - - 0.0003014 47.0
XH2_k127_9106644_0 Zn-dependent hydrolases of the - - - 0.0000000000000000000000000000000000002216 151.0
XH2_k127_9106644_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000007816 101.0
XH2_k127_9106644_2 glucosylceramidase activity - - - 0.000000000000001269 82.0
XH2_k127_9106644_3 Subtilase family K13277 GO:0005575,GO:0005576 - 0.0003514 53.0
XH2_k127_915376_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
XH2_k127_915376_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
XH2_k127_9241220_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 422.0
XH2_k127_9241220_1 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 411.0
XH2_k127_9241220_2 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001945 260.0
XH2_k127_9241220_3 Belongs to the RimK family K05827 - 6.3.2.43 0.00000000000000000000002082 100.0
XH2_k127_9266244_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 600.0
XH2_k127_9266244_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 414.0
XH2_k127_9266244_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000398 171.0
XH2_k127_9266244_3 Thiamine biosynthesis protein (ThiI) K06920 - 6.3.4.20 0.0000000000000000000000000000000000004726 147.0
XH2_k127_9266244_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000004979 105.0
XH2_k127_9266244_5 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0007833 48.0
XH2_k127_9291167_0 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 310.0
XH2_k127_9291167_1 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000000000000000000001515 156.0
XH2_k127_9291167_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000000000003847 141.0
XH2_k127_9291167_3 Ribosomal protein S26e K02976 - - 0.0000000000000000000000001206 108.0
XH2_k127_9291167_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000001266 109.0
XH2_k127_9294865_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 398.0
XH2_k127_9294865_1 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
XH2_k127_9294865_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000002862 128.0
XH2_k127_9326476_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 380.0
XH2_k127_9326476_1 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002579 272.0
XH2_k127_9326476_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000002227 233.0
XH2_k127_9326476_3 TIGRFAM methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.000000000000000000000000000000001092 143.0
XH2_k127_9326476_4 EamA-like transporter family - - - 0.000000000000000000001499 105.0
XH2_k127_9326476_5 COG1977 Molybdopterin converting factor, small subunit K03636 - - 0.00003046 49.0
XH2_k127_9424136_0 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009113 254.0
XH2_k127_9424136_1 DNA polymerase beta domain protein region K07073 - - 0.000000000000000000000000031 111.0
XH2_k127_9480117_0 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000001497 127.0
XH2_k127_9591007_0 Heat shock 70 kDa protein K04043 - - 2.824e-236 757.0
XH2_k127_9591007_1 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 483.0
XH2_k127_9591007_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 353.0
XH2_k127_9591007_3 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 295.0
XH2_k127_9591007_4 metal ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000004545 226.0
XH2_k127_9591007_5 PFAM Creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000003464 190.0
XH2_k127_9591007_6 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000003865 159.0
XH2_k127_9591007_7 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000004617 160.0
XH2_k127_9591007_8 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products - - - 0.00000000000000000000006694 104.0
XH2_k127_9591007_9 - - - - 0.0000000000000000189 87.0
XH2_k127_9597789_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 344.0
XH2_k127_9597789_1 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000003846 183.0
XH2_k127_9597789_2 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000003158 154.0
XH2_k127_9597789_3 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000009521 79.0
XH2_k127_9611500_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000006261 171.0
XH2_k127_9611500_1 - - - - 0.00000000000000000000000000000000001222 141.0
XH2_k127_9623692_0 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000002166 152.0
XH2_k127_9623692_1 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000004202 101.0
XH2_k127_9623692_2 - - - - 0.000000000000001101 87.0
XH2_k127_9658296_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 407.0
XH2_k127_9658296_1 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000002909 237.0
XH2_k127_9658296_10 NUDIX domain - - - 0.0000000000000000000005382 101.0
XH2_k127_9658296_11 Domain of unknown function (DUF1874) - - - 0.0000000004533 64.0
XH2_k127_9658296_12 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0007178 45.0
XH2_k127_9658296_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000005288 221.0
XH2_k127_9658296_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000008488 224.0
XH2_k127_9658296_4 Reversibly glycosylated polypeptide - - - 0.000000000000000000000000000000000000000000000000003002 201.0
XH2_k127_9658296_5 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000001724 179.0
XH2_k127_9658296_6 methyltransferase activity - - - 0.0000000000000000000000000000000000000003926 158.0
XH2_k127_9658296_7 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000005833 145.0
XH2_k127_9658296_8 small multi-drug export - - - 0.00000000000000000000000000001729 123.0
XH2_k127_9658296_9 PFAM peptidase M50 - - - 0.0000000000000000000000000001722 126.0
XH2_k127_9687318_0 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 361.0
XH2_k127_9687318_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 317.0
XH2_k127_9687318_2 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000006478 175.0
XH2_k127_9687318_3 Starch synthase catalytic domain - - - 0.00000000000002068 81.0
XH2_k127_9810524_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000004975 272.0
XH2_k127_9810524_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003916 203.0
XH2_k127_9823261_0 Domain of unknown function (DUF1297) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 456.0
XH2_k127_9823261_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 352.0
XH2_k127_9823261_2 Iron-containing alcohol dehydrogenase K19954 - - 0.00000000000000000000000000000000000000000000000000000000000000002227 238.0
XH2_k127_9823261_3 PFAM purine or other phosphorylase, family 1 K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000001269 188.0
XH2_k127_9823261_4 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000005627 133.0
XH2_k127_9823261_5 UPF0292 protein - - - 0.0000002806 58.0
XH2_k127_9867116_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.759e-227 726.0
XH2_k127_9867116_1 Secreted protein with C-terminal beta-propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 363.0
XH2_k127_9867116_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000001086 173.0
XH2_k127_9867116_3 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000007554 168.0
XH2_k127_9867116_4 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000001606 100.0
XH2_k127_9882397_0 PFAM pyruvate carboxyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 594.0
XH2_k127_9882397_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001463 280.0
XH2_k127_9882397_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005709 280.0
XH2_k127_9882397_3 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004314 269.0
XH2_k127_9882397_4 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000001714 228.0
XH2_k127_9882397_5 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000001039 228.0
XH2_k127_9882397_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
XH2_k127_9882397_7 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001597 205.0
XH2_k127_9882397_8 NADPH-dependent glutamate synthase beta chain and related K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000001789 134.0
XH2_k127_9882397_9 RNA binding K07581 - - 0.00000000005943 69.0
XH2_k127_9896829_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 405.0
XH2_k127_9896829_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 341.0
XH2_k127_9896829_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 304.0
XH2_k127_9896829_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002467 282.0
XH2_k127_9896829_4 - - - - 0.000000000000000000001733 104.0