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Overview

ID MAG04422
Name XH2_bin.6
Sample SMP0119
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family UBA6910
Genus UBA6910
Species
Assembly information
Completeness (%) 81.68
Contamination (%) 5.62
GC content (%) 69.0
N50 (bp) 4,084
Genome size (bp) 2,035,967

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2264

Gene name Description KEGG GOs EC E-value Score Sequence
XH2_k127_10008876_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009104 480.0
XH2_k127_10008876_2 serine threonine protein kinase - - - 0.0000000000000000000000004184 106.0
XH2_k127_10008876_3 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000509 88.0
XH2_k127_10017394_0 protein synthesis factor, GTP-binding K06207 - - 2.741e-314 970.0
XH2_k127_10017394_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 591.0
XH2_k127_10017394_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 396.0
XH2_k127_10017394_3 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 364.0
XH2_k127_10017394_4 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000006599 231.0
XH2_k127_10017394_5 Acyl-ACP thioesterase - - - 0.0000000000000000000000000000000000000000000002125 183.0
XH2_k127_10022358_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 4.23e-272 846.0
XH2_k127_10022358_1 Cytochrome c bacterial - - - 0.00000000000000000000000000000003563 137.0
XH2_k127_10041690_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.106e-266 835.0
XH2_k127_10041690_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 298.0
XH2_k127_10041690_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000153 250.0
XH2_k127_10041690_3 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000001309 103.0
XH2_k127_10055811_0 ABC transporter - - - 3.553e-290 898.0
XH2_k127_10055811_1 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001369 269.0
XH2_k127_10055811_2 - - - - 0.000000000000000000000000000000000000000003362 170.0
XH2_k127_10055811_3 protein conserved in bacteria - - - 0.00000000000000000000000000001729 123.0
XH2_k127_10098624_0 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000002548 215.0
XH2_k127_10098624_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000005771 108.0
XH2_k127_10098624_2 - - - - 0.000000000000009139 81.0
XH2_k127_10098624_3 - - - - 0.0000000002147 65.0
XH2_k127_10102688_0 GMP synthase C terminal domain K01951 - 6.3.5.2 1.029e-266 825.0
XH2_k127_10102688_1 S23 ribosomal protein - - - 0.0000000000000000000004183 97.0
XH2_k127_1011010_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2058.0
XH2_k127_1011010_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000001089 154.0
XH2_k127_1011010_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000368 102.0
XH2_k127_10127032_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 553.0
XH2_k127_10127032_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 481.0
XH2_k127_10127032_2 PFAM peptidylprolyl isomerase FKBP-type K03772,K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000001048 198.0
XH2_k127_10127032_3 4-carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000009594 171.0
XH2_k127_10127032_4 PFAM Cupin 2 conserved barrel domain protein K11312 - - 0.0000000000000000000000000000000000000000292 156.0
XH2_k127_10127032_5 - - - - 0.0000000000000000000000000000000000001164 153.0
XH2_k127_10141069_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 1.109e-241 760.0
XH2_k127_10141069_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 571.0
XH2_k127_10141069_10 Protein of unknown function (DUF3313) - - - 0.00000005674 59.0
XH2_k127_10141069_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 546.0
XH2_k127_10141069_3 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 464.0
XH2_k127_10141069_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 439.0
XH2_k127_10141069_5 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000002286 206.0
XH2_k127_10141069_6 lipid catabolic process - - - 0.00000000000000000000000000000000000000000002558 180.0
XH2_k127_10141069_7 - - - - 0.00000000000000000000000003099 110.0
XH2_k127_10141069_8 - - - - 0.0000000001954 71.0
XH2_k127_10141069_9 - - - - 0.000000008634 58.0
XH2_k127_10150976_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000005237 267.0
XH2_k127_10150976_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001518 243.0
XH2_k127_10150976_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000000001125 177.0
XH2_k127_10170417_0 Domain of unknown function (DUF4396) - - - 0.000000000000000000000000000000000000000000000000000000000000539 216.0
XH2_k127_10170417_1 helix_turn_helix, mercury resistance K08365 - - 0.000000000000000000000000000000005637 132.0
XH2_k127_10170417_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000003078 74.0
XH2_k127_10170417_3 - - - - 0.0000000005304 61.0
XH2_k127_10179063_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 597.0
XH2_k127_10179063_1 EVE domain - - - 0.000000000000000000000000000000000000000005089 155.0
XH2_k127_10239976_0 Cytochrome b(N-terminal)/b6/petB - - - 2.145e-255 802.0
XH2_k127_10239976_1 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000005641 213.0
XH2_k127_10239976_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000003043 186.0
XH2_k127_10239976_3 - - - - 0.0000000000000000000000000000000000000001313 156.0
XH2_k127_10239976_4 Cytochrome b(N-terminal)/b6/petB - - - 0.000000000000000000000000000002824 123.0
XH2_k127_10261858_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.371e-249 783.0
XH2_k127_10261858_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 608.0
XH2_k127_10261858_2 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 556.0
XH2_k127_10261858_3 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 297.0
XH2_k127_10261858_4 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000000000006026 186.0
XH2_k127_10261858_5 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000002101 136.0
XH2_k127_10261858_6 - - - - 0.00000000000000000000000000004369 133.0
XH2_k127_10261858_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000608 61.0
XH2_k127_10264745_0 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 493.0
XH2_k127_10264745_1 - - - - 0.0000000000000002481 85.0
XH2_k127_10264745_2 - - - - 0.0000000002295 64.0
XH2_k127_10275096_0 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 5.837e-281 870.0
XH2_k127_10275096_1 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 578.0
XH2_k127_10275096_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002502 241.0
XH2_k127_10275096_3 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000001328 204.0
XH2_k127_10275096_4 thiolester hydrolase activity K17362 - - 0.00000000000000000000000000000000003362 138.0
XH2_k127_10275096_5 - - - - 0.00000000000000000000000000009257 120.0
XH2_k127_10278362_0 PFAM transposase IS116 IS110 IS902 family - - - 0.000000000000000000000000000000000000000002336 169.0
XH2_k127_10287167_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 5.738e-212 668.0
XH2_k127_10287167_1 Poly-beta-hydroxybutyrate K03821 - - 1.016e-203 649.0
XH2_k127_10287167_2 chemotaxis K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 553.0
XH2_k127_10287167_3 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000001463 222.0
XH2_k127_10287167_4 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000002076 195.0
XH2_k127_10287167_5 PFAM CheW domain protein K02659 - - 0.000000000000000000000000000000000000000000009889 169.0
XH2_k127_10287167_6 TrkA-N domain protein K03499 - - 0.0000000000000000000000000000006041 124.0
XH2_k127_10287167_7 Histidine kinase K02487,K06596 - - 0.000000000000000001402 89.0
XH2_k127_10287876_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.249e-200 634.0
XH2_k127_10287876_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005051 264.0
XH2_k127_10289980_0 Ammonium Transporter Family K03320,K06580 - - 9.619e-196 617.0
XH2_k127_10289980_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 591.0
XH2_k127_10291998_0 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 464.0
XH2_k127_10291998_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 346.0
XH2_k127_10291998_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004826 271.0
XH2_k127_10291998_3 PFAM Aminoacyl-tRNA synthetase, class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000007266 211.0
XH2_k127_10291998_4 MaoC like domain - - - 0.00000000000000000000000000000000000000001332 169.0
XH2_k127_10328528_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 548.0
XH2_k127_10328528_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 359.0
XH2_k127_10328528_2 SecretomeP prediction - - - 0.00000000000000000000000000000000000000000000000000000002847 199.0
XH2_k127_10333900_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 622.0
XH2_k127_10333900_1 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 475.0
XH2_k127_10333900_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002579 259.0
XH2_k127_10333900_3 response regulator - - - 0.00000000000000000000564 98.0
XH2_k127_10368543_0 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000002155 84.0
XH2_k127_10368543_1 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000009283 51.0
XH2_k127_10368543_2 - - - - 0.0004773 52.0
XH2_k127_10373716_0 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 378.0
XH2_k127_10373716_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 338.0
XH2_k127_10373716_2 FR47-like protein - - - 0.0000000000000000000000416 112.0
XH2_k127_10447296_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1731.0
XH2_k127_10447296_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 2.192e-297 921.0
XH2_k127_10447296_10 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000008545 210.0
XH2_k127_10447296_11 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000001107 215.0
XH2_k127_10447296_12 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000002694 218.0
XH2_k127_10447296_13 sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000000001054 200.0
XH2_k127_10447296_14 DsrE/DsrF-like family K07092 - - 0.000000000000000000000000000000000000000000000008346 178.0
XH2_k127_10447296_15 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000009973 150.0
XH2_k127_10447296_16 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000006993 138.0
XH2_k127_10447296_17 Rhodanese Homology Domain - - - 0.00000000000000000000000000001974 120.0
XH2_k127_10447296_18 Prokaryotic N-terminal methylation motif K02650 - - 0.000000000000000000000003004 108.0
XH2_k127_10447296_2 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 578.0
XH2_k127_10447296_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 509.0
XH2_k127_10447296_4 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 509.0
XH2_k127_10447296_5 SMART Elongator protein 3 MiaB NifB K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 474.0
XH2_k127_10447296_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 456.0
XH2_k127_10447296_7 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 416.0
XH2_k127_10447296_8 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 296.0
XH2_k127_10447296_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000009716 236.0
XH2_k127_10451146_0 cation diffusion facilitator family transporter - - - 0.000000000000000000000000001949 115.0
XH2_k127_10451146_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.0000000000001315 70.0
XH2_k127_10451146_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000608 67.0
XH2_k127_10451146_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0002794 47.0
XH2_k127_10480062_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 428.0
XH2_k127_10480062_1 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 312.0
XH2_k127_10480062_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 312.0
XH2_k127_10480062_3 Protein of unknown function (DUF3530) - - - 0.000000000000000000000000000000000000000000000000000000000000000007637 248.0
XH2_k127_10480062_4 haloacid dehalogenase K01560 - 3.8.1.2 0.000000003096 59.0
XH2_k127_10482189_0 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 492.0
XH2_k127_10482189_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000008442 244.0
XH2_k127_10482189_2 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000000000000000000000000000157 118.0
XH2_k127_10482189_3 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000002944 73.0
XH2_k127_1049663_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 408.0
XH2_k127_1049663_1 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000006398 248.0
XH2_k127_10502666_0 FAD binding domain K00394 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 380.0
XH2_k127_10502666_1 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 377.0
XH2_k127_10502666_2 PFAM AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 379.0
XH2_k127_10520670_0 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 587.0
XH2_k127_10520670_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 565.0
XH2_k127_10520670_2 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 467.0
XH2_k127_10520670_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 437.0
XH2_k127_10520670_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 408.0
XH2_k127_10520670_5 S4 RNA-binding domain K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000152 268.0
XH2_k127_10520670_6 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000009474 235.0
XH2_k127_10522815_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 546.0
XH2_k127_10522815_1 - - - - 0.000000000000000000000000000003437 127.0
XH2_k127_1058901_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 591.0
XH2_k127_1058901_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000003444 235.0
XH2_k127_1058901_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000001043 188.0
XH2_k127_1058901_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000001683 65.0
XH2_k127_10626582_0 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 375.0
XH2_k127_10626582_1 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008417 279.0
XH2_k127_10626582_2 pilus assembly protein PilZ K02676 - - 0.000000000000000000000000000000000000000000000005701 175.0
XH2_k127_10626582_3 Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000000000000001312 178.0
XH2_k127_10645810_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000962 508.0
XH2_k127_10645810_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 294.0
XH2_k127_10645810_2 - - - - 0.00000000000003127 76.0
XH2_k127_10653082_0 PFAM Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 444.0
XH2_k127_10653082_1 Cytochrome c - - - 0.00000000000000000000000001133 115.0
XH2_k127_10670453_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1103.0
XH2_k127_10670453_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 334.0
XH2_k127_10670453_2 Ribosomal protein L11 methyltransferase (PrmA) K05929 - 2.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000001603 262.0
XH2_k127_10670453_3 - - - - 0.0000000000000000000000000000001434 132.0
XH2_k127_10670453_4 Protein of unknown function (DUF2933) - - - 0.000000000000000002422 88.0
XH2_k127_10670453_5 Histidine kinase - - - 0.0005102 43.0
XH2_k127_10687500_0 TIGRFAM TIGR03032 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 465.0
XH2_k127_10703695_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 593.0
XH2_k127_10703695_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 427.0
XH2_k127_10703695_2 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.00000000000000000000000000000000000000000000000000000000000005621 218.0
XH2_k127_10703695_3 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000007604 192.0
XH2_k127_10703695_4 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000003937 153.0
XH2_k127_1082552_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.417e-296 918.0
XH2_k127_1082552_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 470.0
XH2_k127_1082552_2 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 319.0
XH2_k127_1082552_3 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 318.0
XH2_k127_1082552_4 Aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000000104 211.0
XH2_k127_1093442_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 7.259e-208 675.0
XH2_k127_1093442_1 ATP adenylyltransferase K00988 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001698 295.0
XH2_k127_1093442_2 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008383 283.0
XH2_k127_1093442_3 - - - - 0.000000000000001179 84.0
XH2_k127_1113006_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 512.0
XH2_k127_1113006_1 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000001885 121.0
XH2_k127_1113640_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.084e-287 887.0
XH2_k127_1113640_1 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003985 265.0
XH2_k127_1113640_2 Protein of unknown function (DUF3106) - - - 0.0000000000000000008618 96.0
XH2_k127_1113640_3 Protein of unknown function (DUF3619) - - - 0.000000000001664 72.0
XH2_k127_1162671_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 598.0
XH2_k127_1162671_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.0000000000000000000000000001474 119.0
XH2_k127_1175296_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 8.17e-253 799.0
XH2_k127_1175296_1 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000001917 138.0
XH2_k127_1175296_2 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000005351 113.0
XH2_k127_1175296_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000005826 93.0
XH2_k127_1221955_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.231e-271 841.0
XH2_k127_1221955_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 381.0
XH2_k127_1221955_2 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 331.0
XH2_k127_1221955_3 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000005804 180.0
XH2_k127_1221955_4 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000000314 82.0
XH2_k127_1221955_5 Cbb3-type cytochrome oxidase K00407 - - 0.0000000000001647 76.0
XH2_k127_1242745_0 Uncharacterized protein family UPF0004 K06168 - 2.8.4.3 3.945e-212 666.0
XH2_k127_1242745_1 phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001076 274.0
XH2_k127_1242745_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000006685 148.0
XH2_k127_1278333_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 518.0
XH2_k127_1278333_1 membrane protein, terc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008451 325.0
XH2_k127_1278333_2 Malic enzyme K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 308.0
XH2_k127_1278333_3 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
XH2_k127_1278333_4 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000001531 180.0
XH2_k127_1278333_5 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000003793 157.0
XH2_k127_1285407_0 FAD binding domain K00394 - 1.8.99.2 6.729e-317 973.0
XH2_k127_1285407_1 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000002092 49.0
XH2_k127_1299969_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2483.0
XH2_k127_1299969_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.651e-239 748.0
XH2_k127_1299969_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 537.0
XH2_k127_1299969_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 490.0
XH2_k127_1299969_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 287.0
XH2_k127_1333229_0 TIGRFAM type I secretion membrane fusion protein, HlyD family K02022,K12537 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 347.0
XH2_k127_1333229_1 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 306.0
XH2_k127_1333229_2 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006194 264.0
XH2_k127_1333229_3 - K09004 - - 0.000000000000000000000000000000000000000000000000000000000006989 212.0
XH2_k127_1333229_4 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000000000000752 155.0
XH2_k127_1338871_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 373.0
XH2_k127_1338871_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002137 273.0
XH2_k127_1338871_2 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000664 213.0
XH2_k127_1358062_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 522.0
XH2_k127_1358062_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000002847 222.0
XH2_k127_1359941_0 Protein export membrane protein K07239 - - 5.411e-237 741.0
XH2_k127_1359941_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 375.0
XH2_k127_1374297_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.787e-249 777.0
XH2_k127_1374297_1 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 286.0
XH2_k127_1374297_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000001714 142.0
XH2_k127_1374297_3 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000001349 113.0
XH2_k127_1385656_0 Homospermidine synthase K00808 - 2.5.1.44 8.668e-216 680.0
XH2_k127_1385656_1 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 589.0
XH2_k127_1385656_10 Protein of unknown function (DUF3567) - - - 0.0000000001082 65.0
XH2_k127_1385656_11 Cytochrome c - - - 0.0000000001766 65.0
XH2_k127_1385656_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 364.0
XH2_k127_1385656_3 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000881 211.0
XH2_k127_1385656_4 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.0000000000000000000000000000000000000000000000002094 186.0
XH2_k127_1385656_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000002941 179.0
XH2_k127_1385656_6 - - - - 0.0000000000000000000000000000000000000000000001514 177.0
XH2_k127_1385656_7 Belongs to the globin family - - - 0.00000000000000000000000006367 114.0
XH2_k127_1385656_8 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000002328 107.0
XH2_k127_1385656_9 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000001707 106.0
XH2_k127_1387431_0 CoA-binding domain protein K09181 - - 0.0 1081.0
XH2_k127_1387431_1 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 1.08e-222 696.0
XH2_k127_1387431_2 Aminotransferase K14261 - - 1.913e-201 654.0
XH2_k127_1387431_3 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 484.0
XH2_k127_1387431_4 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 435.0
XH2_k127_1387431_5 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 313.0
XH2_k127_1387431_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000001761 250.0
XH2_k127_1387431_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000003873 143.0
XH2_k127_1387431_8 Putative diguanylate phosphodiesterase - - - 0.000000000000000001636 101.0
XH2_k127_1387431_9 two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.0000000001362 75.0
XH2_k127_1393992_0 UvrD REP K03657 - 3.6.4.12 6.77e-321 998.0
XH2_k127_1393992_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 542.0
XH2_k127_1393992_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 471.0
XH2_k127_1393992_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000001074 240.0
XH2_k127_1393992_4 - - - - 0.00000000000000000000000000000000000000000007454 169.0
XH2_k127_1418495_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1354.0
XH2_k127_1418495_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 566.0
XH2_k127_1418495_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 462.0
XH2_k127_1418495_3 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 377.0
XH2_k127_1418495_4 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 365.0
XH2_k127_1418495_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000002569 143.0
XH2_k127_1418495_6 Protein of unknown function (DUF721) - - - 0.0000000000001196 83.0
XH2_k127_1418495_7 - - - - 0.0005343 46.0
XH2_k127_1436654_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 343.0
XH2_k127_1436654_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000007811 173.0
XH2_k127_1436654_2 DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000007324 148.0
XH2_k127_1456610_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 561.0
XH2_k127_1456610_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 434.0
XH2_k127_1456610_2 membrane - - - 0.00000000000000000000000000000000000000000000001283 174.0
XH2_k127_1456610_3 Bacterial protein of unknown function (DUF883) - - - 0.000000000000003949 80.0
XH2_k127_147930_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.84e-215 672.0
XH2_k127_147930_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 436.0
XH2_k127_147930_2 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 408.0
XH2_k127_1486229_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 428.0
XH2_k127_1486229_1 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000004539 237.0
XH2_k127_1486229_2 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000000000000000000001364 191.0
XH2_k127_1486229_3 DJ-1/PfpI family - - - 0.00000000000000000000000000008307 117.0
XH2_k127_1486229_4 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000002304 121.0
XH2_k127_1489008_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 488.0
XH2_k127_1489008_1 amino acid ABC transporter K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 484.0
XH2_k127_1489008_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 390.0
XH2_k127_1489008_3 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000007362 233.0
XH2_k127_1489008_4 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000007194 131.0
XH2_k127_1489008_5 Protein of unknown function, DUF255 K06888 - - 0.00000001079 58.0
XH2_k127_14935_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 499.0
XH2_k127_14935_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 492.0
XH2_k127_14935_2 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000534 110.0
XH2_k127_14935_3 competence protein - - - 0.00008328 46.0
XH2_k127_1497134_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 440.0
XH2_k127_1497134_1 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.000001016 61.0
XH2_k127_1508506_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.0 1007.0
XH2_k127_1508506_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 307.0
XH2_k127_1508506_2 oxidoreductase DsbE K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001636 278.0
XH2_k127_1508506_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
XH2_k127_1508506_4 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000000000001168 179.0
XH2_k127_1508506_5 Tetratricopeptide repeat K02200 - - 0.0000000000002571 79.0
XH2_k127_1508506_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000001609 68.0
XH2_k127_1509908_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 399.0
XH2_k127_1509908_1 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 299.0
XH2_k127_1509908_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 281.0
XH2_k127_1509908_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000001785 137.0
XH2_k127_152732_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1229.0
XH2_k127_1529616_0 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 554.0
XH2_k127_1529616_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007265 266.0
XH2_k127_1529616_2 Cytochrome c, class I - - - 0.0000000000000000000000000000000005513 134.0
XH2_k127_1542058_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 566.0
XH2_k127_1542058_1 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 356.0
XH2_k127_1542058_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 284.0
XH2_k127_1542058_3 Protein of unknown function (DUF3568) - - - 0.000000000000000000000617 101.0
XH2_k127_1550027_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 291.0
XH2_k127_1550027_1 transport-associated - - - 0.0000000000000000000000000000000000000000000000000004089 197.0
XH2_k127_1550027_2 SnoaL-like domain K01822 - 5.3.3.1 0.00000000000000000000000000000000001573 138.0
XH2_k127_1580843_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 441.0
XH2_k127_1580843_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 399.0
XH2_k127_1580843_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 352.0
XH2_k127_1580843_3 ThiS family K03154 - - 0.000000000000000000007998 93.0
XH2_k127_1592463_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.492e-203 638.0
XH2_k127_1592463_1 Translation-initiation factor 2 K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 344.0
XH2_k127_1592463_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 332.0
XH2_k127_1592463_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000004102 160.0
XH2_k127_1592463_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000009416 145.0
XH2_k127_1602404_0 type II secretion system protein K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 470.0
XH2_k127_1602404_1 type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000002007 211.0
XH2_k127_1604177_0 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 376.0
XH2_k127_1604177_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 288.0
XH2_k127_1604177_2 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001023 244.0
XH2_k127_1604177_3 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000001008 219.0
XH2_k127_1604177_4 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000002112 175.0
XH2_k127_161995_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 540.0
XH2_k127_161995_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 295.0
XH2_k127_161995_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000001497 143.0
XH2_k127_161995_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000001237 91.0
XH2_k127_1629672_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 476.0
XH2_k127_1629672_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 305.0
XH2_k127_1658686_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 578.0
XH2_k127_1658686_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000003115 104.0
XH2_k127_1660270_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 446.0
XH2_k127_1660270_1 PFAM transglutaminase domain protein - - - 0.0000000000000000000002688 113.0
XH2_k127_1669523_0 Sigma-54 interaction domain K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 599.0
XH2_k127_1669523_1 (ABC) transporter - - - 0.00000000002502 71.0
XH2_k127_1673307_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 567.0
XH2_k127_1673307_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 407.0
XH2_k127_1673307_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 376.0
XH2_k127_1673307_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 348.0
XH2_k127_1673307_4 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001497 269.0
XH2_k127_1673307_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000001216 217.0
XH2_k127_1673307_6 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000001751 134.0
XH2_k127_1676331_0 Von Willebrand factor A K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 586.0
XH2_k127_1676331_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 474.0
XH2_k127_1676331_2 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 475.0
XH2_k127_1676331_3 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 412.0
XH2_k127_1676331_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 326.0
XH2_k127_1676331_5 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006014 289.0
XH2_k127_1676331_6 FR47-like protein - - - 0.0000000000000000000000000000000003183 150.0
XH2_k127_1676331_7 TIR domain - - - 0.000000000000000000000000000005355 138.0
XH2_k127_1676331_8 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.0000000000000000000021 96.0
XH2_k127_1676331_9 c-di-gmp phosphodiesterase - - - 0.0000002088 55.0
XH2_k127_1710908_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1040.0
XH2_k127_1710908_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000002304 209.0
XH2_k127_1713250_0 argininosuccinate lyase K01755 - 4.3.2.1 2.629e-236 738.0
XH2_k127_1713250_1 PFAM Fructosamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 392.0
XH2_k127_1713250_2 Histidine kinase K08082 - 2.7.13.3 0.0000000007609 63.0
XH2_k127_1734925_0 Fumarase C C-terminus K01744 - 4.3.1.1 1.261e-270 843.0
XH2_k127_1734925_1 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 8.415e-245 760.0
XH2_k127_1734925_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 531.0
XH2_k127_1734925_3 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003598 271.0
XH2_k127_1734925_4 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000002455 198.0
XH2_k127_1734925_5 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000008257 160.0
XH2_k127_1759452_0 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 420.0
XH2_k127_1759452_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000009118 201.0
XH2_k127_1759452_2 glycosyl transferase family - - - 0.0000000000000000000000000000000000000000000000000004924 194.0
XH2_k127_1759452_3 Radical SAM - - - 0.00000000000000000000000000000000000000000000000006527 180.0
XH2_k127_1779004_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 291.0
XH2_k127_1779004_1 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000007947 190.0
XH2_k127_178671_0 Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 406.0
XH2_k127_178671_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 308.0
XH2_k127_178671_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000002162 185.0
XH2_k127_178671_3 Transglycosylase associated protein - - - 0.0000000000000000000000000000006098 124.0
XH2_k127_178671_4 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000001042 119.0
XH2_k127_1805365_0 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 539.0
XH2_k127_1805365_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 476.0
XH2_k127_1805365_2 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 303.0
XH2_k127_1805365_3 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000001094 131.0
XH2_k127_1805365_4 mechanosensitive ion channel - - - 0.000000000000000000000000000000004007 130.0
XH2_k127_1805365_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001906 91.0
XH2_k127_1809916_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 9.203e-201 630.0
XH2_k127_1809916_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000187 124.0
XH2_k127_1828234_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 452.0
XH2_k127_1828234_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 323.0
XH2_k127_1828234_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 311.0
XH2_k127_1828234_3 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
XH2_k127_1828234_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000002435 231.0
XH2_k127_1828234_5 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.00000000000000000000000000000000000005273 148.0
XH2_k127_1828234_6 rieske 2fe-2s - - - 0.0000000000000000000000000000000007966 142.0
XH2_k127_1828234_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000007202 98.0
XH2_k127_1847494_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 502.0
XH2_k127_1847494_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000001455 225.0
XH2_k127_1866878_0 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 438.0
XH2_k127_1866878_1 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 262.0
XH2_k127_1866878_2 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000007348 204.0
XH2_k127_1888619_0 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1053.0
XH2_k127_1888619_1 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000007155 183.0
XH2_k127_1891825_0 WD40 repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 408.0
XH2_k127_1907400_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 547.0
XH2_k127_1907400_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000001304 226.0
XH2_k127_1911830_0 Cache 3/Cache 2 fusion domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 454.0
XH2_k127_1935520_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 527.0
XH2_k127_1935520_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 460.0
XH2_k127_1935520_2 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003914 279.0
XH2_k127_1935520_3 - - - - 0.000000001946 61.0
XH2_k127_1946425_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 2.58e-245 769.0
XH2_k127_1946425_1 Oxaloacetate decarboxylase, gamma chain - - - 0.0006291 42.0
XH2_k127_1946425_2 Saccharopine dehydrogenase - - - 0.0007318 42.0
XH2_k127_1951599_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.289e-207 652.0
XH2_k127_1951599_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 445.0
XH2_k127_1951599_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 411.0
XH2_k127_1951599_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000001741 243.0
XH2_k127_1951599_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000008737 145.0
XH2_k127_1951599_5 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000053 124.0
XH2_k127_1976235_0 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 556.0
XH2_k127_1976235_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 433.0
XH2_k127_1999_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 2.265e-311 964.0
XH2_k127_2016069_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 2.068e-244 759.0
XH2_k127_2016069_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 6.395e-239 754.0
XH2_k127_2016069_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 563.0
XH2_k127_2016069_3 Transcriptional regulator K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 454.0
XH2_k127_2016069_4 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 375.0
XH2_k127_2016069_5 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000005643 126.0
XH2_k127_2016069_6 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000003826 106.0
XH2_k127_202775_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 1.266e-276 865.0
XH2_k127_202775_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001422 246.0
XH2_k127_202775_2 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000053 180.0
XH2_k127_202775_3 Belongs to the glycosyl hydrolase 57 family - - - 0.0006651 42.0
XH2_k127_2057181_0 Thioredoxin-like K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 340.0
XH2_k127_2057181_1 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000002929 144.0
XH2_k127_2057181_2 Peptidase S16, lon domain protein K07157 - - 0.00000000000000000000000001856 112.0
XH2_k127_2101369_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1570.0
XH2_k127_2101369_1 Sugar (and other) transporter - - - 1.932e-200 637.0
XH2_k127_2101369_2 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 369.0
XH2_k127_2101369_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000001465 214.0
XH2_k127_2101369_4 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000002606 212.0
XH2_k127_2101369_5 Hypoxia induced protein conserved region - - - 0.000006058 51.0
XH2_k127_2118009_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 5.571e-234 734.0
XH2_k127_2118009_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 4.032e-229 717.0
XH2_k127_2118009_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000004746 235.0
XH2_k127_2147832_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.828e-194 618.0
XH2_k127_2147832_1 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 565.0
XH2_k127_2147832_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 513.0
XH2_k127_2147832_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 450.0
XH2_k127_2147832_4 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 437.0
XH2_k127_2147832_5 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00001405 51.0
XH2_k127_2150226_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 608.0
XH2_k127_2150226_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 401.0
XH2_k127_2150226_2 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 349.0
XH2_k127_2187244_0 AAA domain - - - 2.263e-245 774.0
XH2_k127_2187562_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1240.0
XH2_k127_2187562_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 361.0
XH2_k127_2187562_2 regulatory protein Crp K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003473 273.0
XH2_k127_2187562_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004396 258.0
XH2_k127_2187562_4 Psort location Cytoplasmic, score 8.96 K03437 - - 0.0000002968 53.0
XH2_k127_2213627_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 484.0
XH2_k127_2213627_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 456.0
XH2_k127_2213627_2 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000007088 208.0
XH2_k127_2213627_3 Dihydrofolate reductase K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000001821 196.0
XH2_k127_2213627_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000005357 179.0
XH2_k127_2213627_5 - - - - 0.00000000003117 66.0
XH2_k127_223210_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 4.577e-214 668.0
XH2_k127_223210_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 405.0
XH2_k127_223210_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 400.0
XH2_k127_223210_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 293.0
XH2_k127_223210_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000001126 191.0
XH2_k127_223210_5 transcriptional regulators - - - 0.00000000000000000000000000000000003531 153.0
XH2_k127_2232710_0 Methionine synthase K00548 - 2.1.1.13 1.337e-282 875.0
XH2_k127_2232710_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 417.0
XH2_k127_2232710_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000006826 154.0
XH2_k127_2239655_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1247.0
XH2_k127_2239655_1 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1148.0
XH2_k127_2239655_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000009115 76.0
XH2_k127_2239655_11 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000003406 62.0
XH2_k127_2239655_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 7.793e-199 629.0
XH2_k127_2239655_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 490.0
XH2_k127_2239655_4 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 441.0
XH2_k127_2239655_5 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003347 244.0
XH2_k127_2239655_6 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000000000000000008739 201.0
XH2_k127_2239655_7 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000002659 136.0
XH2_k127_2239655_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000004553 111.0
XH2_k127_2239655_9 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000005421 75.0
XH2_k127_2244427_0 type I secretion outer membrane protein, TolC K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 431.0
XH2_k127_2244427_1 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 415.0
XH2_k127_2244427_2 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007908 277.0
XH2_k127_2244427_3 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000000002258 138.0
XH2_k127_2244427_4 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000002762 79.0
XH2_k127_225548_0 Putative amidoligase enzyme (DUF2126) - - - 8.955e-290 899.0
XH2_k127_225548_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 573.0
XH2_k127_225548_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 361.0
XH2_k127_225548_3 - - - - 0.000000000000000000000000000000000000000002155 165.0
XH2_k127_2295872_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 492.0
XH2_k127_2295872_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 491.0
XH2_k127_2295872_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 301.0
XH2_k127_2295872_3 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 297.0
XH2_k127_2295872_4 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 286.0
XH2_k127_2295872_5 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000000004579 218.0
XH2_k127_2295872_6 FOG HPt domain K20976 - - 0.00000001095 61.0
XH2_k127_2304442_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 7.899e-266 831.0
XH2_k127_2304442_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.927e-231 722.0
XH2_k127_2304442_2 Isocitrate lyase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 327.0
XH2_k127_2304442_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003476 243.0
XH2_k127_2310154_0 Domain of unknown function (DUF1993) K09983 - - 0.0000000000000000000000000000000000000000000000000000000000000000001996 233.0
XH2_k127_2310154_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000005593 233.0
XH2_k127_2310154_2 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000001562 191.0
XH2_k127_2310154_3 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000002773 166.0
XH2_k127_2335471_0 type IV pilus secretin PilQ K02666 - - 2.22e-231 739.0
XH2_k127_2335471_1 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 1.804e-203 642.0
XH2_k127_2335471_2 Type IV pilus assembly protein PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 526.0
XH2_k127_2335471_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 309.0
XH2_k127_2335471_4 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000001007 246.0
XH2_k127_2335471_5 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000000000002153 213.0
XH2_k127_2335471_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000004425 218.0
XH2_k127_2335471_7 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000004529 171.0
XH2_k127_2353701_0 ABC transporter transmembrane region K06147 - - 2.3e-302 936.0
XH2_k127_2357661_0 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 554.0
XH2_k127_2361212_0 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001059 255.0
XH2_k127_2361212_1 SpoIIAA-like - - - 0.0000000000000000000000000000000000001377 144.0
XH2_k127_2361212_2 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000004404 60.0
XH2_k127_2390942_0 AAA domain, putative AbiEii toxin, Type IV TA system K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000007091 238.0
XH2_k127_2390942_1 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000004398 230.0
XH2_k127_2430425_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 561.0
XH2_k127_2430425_1 Histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 374.0
XH2_k127_2435563_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 522.0
XH2_k127_2435563_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 308.0
XH2_k127_2435563_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 265.0
XH2_k127_2435563_3 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.00000000000000000000003578 101.0
XH2_k127_2439955_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 452.0
XH2_k127_2470402_0 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 451.0
XH2_k127_2470402_1 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000009633 245.0
XH2_k127_24826_0 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 422.0
XH2_k127_24826_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001171 260.0
XH2_k127_24826_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000003235 253.0
XH2_k127_24826_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000003902 176.0
XH2_k127_2486095_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 9.732e-197 618.0
XH2_k127_2486095_1 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 542.0
XH2_k127_2486095_2 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 514.0
XH2_k127_2486095_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 304.0
XH2_k127_2486095_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000002468 123.0
XH2_k127_2486095_5 Polysaccharide deacetylase - - - 0.0000000000000000000000005968 116.0
XH2_k127_2498732_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 2.046e-271 840.0
XH2_k127_2498732_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.824e-253 794.0
XH2_k127_2498732_10 maturation - - - 0.00000000000000000000000000000000000000000000001654 175.0
XH2_k127_2498732_11 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000005371 156.0
XH2_k127_2498732_12 Protein of unknown function (DUF504) - - - 0.0000001901 57.0
XH2_k127_2498732_13 AAA domain K07028 - - 0.0001742 47.0
XH2_k127_2498732_2 PFAM ABC-1 domain protein K03688 - - 2.975e-246 773.0
XH2_k127_2498732_3 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 510.0
XH2_k127_2498732_4 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 364.0
XH2_k127_2498732_5 NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 335.0
XH2_k127_2498732_6 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007906 274.0
XH2_k127_2498732_7 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000001713 237.0
XH2_k127_2498732_8 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000781 191.0
XH2_k127_2498732_9 - - - - 0.0000000000000000000000000000000000000000000000029 192.0
XH2_k127_2539852_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 5.302e-234 728.0
XH2_k127_2539852_1 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
XH2_k127_2545268_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 512.0
XH2_k127_2545268_1 response regulator K02483,K07666,K07774 - - 0.0000000000000000000000000005751 115.0
XH2_k127_2562578_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 5.482e-270 842.0
XH2_k127_2562578_1 Competence protein ComEC Rec2 K02238 - - 9.224e-203 647.0
XH2_k127_2562578_2 Xylose isomerase-like TIM barrel K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 380.0
XH2_k127_2562578_3 Belongs to the pseudouridine synthase RsuA family K06178,K06181 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003584 291.0
XH2_k127_2562578_4 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000002898 246.0
XH2_k127_2562578_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000001022 203.0
XH2_k127_2562578_6 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000009684 203.0
XH2_k127_2562578_7 Acyltransferase family - - - 0.000000000000000000000000000000000001782 152.0
XH2_k127_2565994_0 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 376.0
XH2_k127_2565994_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000008263 186.0
XH2_k127_2565994_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000005015 141.0
XH2_k127_2573242_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 349.0
XH2_k127_2573242_1 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 290.0
XH2_k127_2573242_2 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000001416 183.0
XH2_k127_2650422_0 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 606.0
XH2_k127_2650422_1 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000001864 127.0
XH2_k127_2650422_2 diguanylate cyclase - - - 0.000000000000000000000000000005988 125.0
XH2_k127_2665676_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 415.0
XH2_k127_2665676_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 342.0
XH2_k127_2665676_2 Transcriptional regulatory protein, C terminal K02483,K07658 - - 0.00000000000000000000000000000000000000000000000000006393 197.0
XH2_k127_2665676_3 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.0000000000000000000000000000000000000000007153 168.0
XH2_k127_2665676_4 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.000000000000000000000000000000000000007146 164.0
XH2_k127_2665676_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000005707 57.0
XH2_k127_268888_0 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 514.0
XH2_k127_268888_1 Histidine kinase - - - 0.00000000000000000000000000005097 119.0
XH2_k127_2708732_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1054.0
XH2_k127_2708732_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 576.0
XH2_k127_2708732_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 316.0
XH2_k127_2708732_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009118 273.0
XH2_k127_2708732_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000201 228.0
XH2_k127_2708732_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000000001011 202.0
XH2_k127_2708732_6 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000009195 132.0
XH2_k127_2708732_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000001134 95.0
XH2_k127_2728272_0 Periplasmic binding protein domain K11959 - - 2.233e-204 637.0
XH2_k127_2728272_1 Branched-chain amino acid transport system / permease component K11960 - - 0.0000000000000000000000000000000000000000000000000000001504 205.0
XH2_k127_2733967_0 PFAM extracellular solute-binding protein family 1 K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 480.0
XH2_k127_2733967_1 phosphate transport system K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 459.0
XH2_k127_2733967_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 439.0
XH2_k127_2733967_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 425.0
XH2_k127_2734423_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 529.0
XH2_k127_2734423_1 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 481.0
XH2_k127_27406_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 8.388e-240 749.0
XH2_k127_27406_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000003507 121.0
XH2_k127_2758156_0 ribonuclease, Rne Rng family K08301 - - 3.939e-234 748.0
XH2_k127_2758156_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004604 271.0
XH2_k127_2758156_2 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000007218 203.0
XH2_k127_2758156_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000001836 134.0
XH2_k127_2758156_4 DUF167 K09131 - - 0.0000000000000000000000000002838 117.0
XH2_k127_2763547_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1201.0
XH2_k127_2796440_0 DNA polymerase X family K02347 - - 1.553e-251 792.0
XH2_k127_2796440_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000008443 231.0
XH2_k127_2796440_2 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000000958 148.0
XH2_k127_2796440_3 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000007478 58.0
XH2_k127_2797062_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 389.0
XH2_k127_2797062_1 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000001727 202.0
XH2_k127_2820557_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 3.989e-240 773.0
XH2_k127_2820557_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 590.0
XH2_k127_2820557_10 Resolvase, N terminal domain - - - 0.000000000003019 67.0
XH2_k127_2820557_11 - - - - 0.0000000004926 64.0
XH2_k127_2820557_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 468.0
XH2_k127_2820557_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 412.0
XH2_k127_2820557_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 344.0
XH2_k127_2820557_5 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008924 258.0
XH2_k127_2820557_6 Protein of unknown function (DUF1318) K09978 - - 0.000000000000000000000000000000000000000000000000000000018 199.0
XH2_k127_2820557_7 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000003542 196.0
XH2_k127_2820557_8 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000004641 189.0
XH2_k127_2820557_9 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000001981 167.0
XH2_k127_2836395_0 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 426.0
XH2_k127_2836395_1 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 0.0000000000000000000000000000000000000003196 153.0
XH2_k127_2836395_2 Fe-S protein K06938 - - 0.000000001233 61.0
XH2_k127_2839739_0 aminopeptidase N K01256 - 3.4.11.2 1.579e-287 902.0
XH2_k127_2839739_1 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003867 224.0
XH2_k127_2874953_0 type IV-A pilus assembly ATPase PilB K02652 - - 7.479e-250 783.0
XH2_k127_2874953_1 PFAM type II secretion system K02653 - - 8.821e-201 631.0
XH2_k127_2874953_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 420.0
XH2_k127_2874953_3 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 378.0
XH2_k127_2874953_4 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 342.0
XH2_k127_2874953_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000009652 214.0
XH2_k127_2874953_6 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000005524 91.0
XH2_k127_2874953_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000001125 66.0
XH2_k127_2884148_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 449.0
XH2_k127_2884148_1 PFAM LemA family K03744 - - 0.000000000000000000000000000002461 122.0
XH2_k127_2889252_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 374.0
XH2_k127_2889252_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000001409 202.0
XH2_k127_2889252_2 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000597 191.0
XH2_k127_2889252_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000003609 123.0
XH2_k127_2892341_0 PQQ-like domain K00114 - 1.1.2.8 5.149e-310 962.0
XH2_k127_2892341_1 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 381.0
XH2_k127_2892341_2 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 297.0
XH2_k127_2892341_3 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005534 263.0
XH2_k127_2892341_4 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000003346 188.0
XH2_k127_2892341_5 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.000000000000000000000000000000000000000000000000004129 195.0
XH2_k127_2905602_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
XH2_k127_2905602_1 peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005812 257.0
XH2_k127_2905602_2 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000003285 78.0
XH2_k127_2913972_0 TraB family K09973 - - 0.000000000000000000000000000000001366 138.0
XH2_k127_2913972_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000001708 61.0
XH2_k127_2924173_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.748e-201 633.0
XH2_k127_2924173_1 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000001574 204.0
XH2_k127_2924173_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0003284 46.0
XH2_k127_2924324_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.612e-247 772.0
XH2_k127_2924324_1 Belongs to the GARS family K01945 - 6.3.4.13 3.112e-206 649.0
XH2_k127_2924324_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 554.0
XH2_k127_2924324_3 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000000007653 116.0
XH2_k127_2924901_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 576.0
XH2_k127_2924901_1 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 541.0
XH2_k127_2924901_2 Low molecular weight phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009167 252.0
XH2_k127_2924901_3 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000002076 168.0
XH2_k127_2924901_4 transcriptional regulators K03892 - - 0.00000000000000000000000000006755 121.0
XH2_k127_2924901_5 Thioredoxin domain - - - 0.0000000000000000000002958 98.0
XH2_k127_2924901_6 4Fe-4S dicluster domain - - - 0.000000000004093 72.0
XH2_k127_2927812_0 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002297 270.0
XH2_k127_2927812_1 AsmA family K07289,K07290 - - 0.0000000000000000000000000000000000001519 151.0
XH2_k127_2927812_2 Acetyltransferase (GNAT) domain K02348 - - 0.0000001116 53.0
XH2_k127_2937465_0 Formyl transferase K19640 - - 3.323e-225 713.0
XH2_k127_2937465_1 Two component, sigma54 specific, transcriptional regulator, Fis family K19641 - - 4.322e-207 658.0
XH2_k127_2937465_2 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 580.0
XH2_k127_2937465_3 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 513.0
XH2_k127_2937465_4 NiFe/NiFeSe hydrogenase small subunit C-terminal K00534 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 506.0
XH2_k127_2962422_0 Malic enzyme K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 424.0
XH2_k127_2962422_1 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
XH2_k127_296307_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1045.0
XH2_k127_296307_1 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000004496 163.0
XH2_k127_2963702_0 Male sterility - - - 1.6e-270 846.0
XH2_k127_2963702_1 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 392.0
XH2_k127_2963702_2 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000000000000000000000009059 136.0
XH2_k127_2985414_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 429.0
XH2_k127_2985414_1 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 375.0
XH2_k127_2985414_2 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004284 280.0
XH2_k127_3019153_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 578.0
XH2_k127_3019153_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005278 271.0
XH2_k127_3019153_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000001748 214.0
XH2_k127_3019153_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000002293 140.0
XH2_k127_3020961_0 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008499 368.0
XH2_k127_3020961_1 - - - - 0.0000000000000000000000000000000000000000006578 165.0
XH2_k127_3020961_2 Glycogen debranching enzyme - - - 0.0000000000000000000000000000009209 121.0
XH2_k127_3020961_3 Ion channel - - - 0.000000000000000000000006964 113.0
XH2_k127_3044111_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1014.0
XH2_k127_3044111_1 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000006922 224.0
XH2_k127_3044111_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000002764 111.0
XH2_k127_3044111_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000004767 91.0
XH2_k127_3059524_0 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 5.116e-309 953.0
XH2_k127_3059524_1 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 455.0
XH2_k127_3059524_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 334.0
XH2_k127_3059524_3 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 282.0
XH2_k127_3059524_4 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004155 282.0
XH2_k127_3059524_5 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000001383 141.0
XH2_k127_3059524_6 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000002126 129.0
XH2_k127_3082391_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 545.0
XH2_k127_3082391_1 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 471.0
XH2_k127_3082391_2 Zinc-finger domain - - - 0.0000000000000000000000000002296 115.0
XH2_k127_3082391_3 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000008891 93.0
XH2_k127_3117447_0 COG0744 Membrane carboxypeptidase (penicillin-binding protein) - - - 1.5e-323 1020.0
XH2_k127_3117447_1 PFAM aspartate glutamate uridylate kinase - - - 0.00000000000000000001517 94.0
XH2_k127_3123823_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 505.0
XH2_k127_3123823_1 Phosphopantetheine attachment site - - - 0.000000000000007518 74.0
XH2_k127_3149571_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 596.0
XH2_k127_3149571_1 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000004487 224.0
XH2_k127_3149571_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000003951 71.0
XH2_k127_3165870_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 499.0
XH2_k127_3165870_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 381.0
XH2_k127_3165870_2 Soluble lytic murein transglycosylase L domain K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 322.0
XH2_k127_3196277_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.168e-274 854.0
XH2_k127_3196277_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000001872 165.0
XH2_k127_3196277_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000004407 140.0
XH2_k127_3250957_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 449.0
XH2_k127_3250957_1 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 298.0
XH2_k127_3250957_2 Type II secretion system protein B K02451 - - 0.00000000000000003609 85.0
XH2_k127_3287747_0 O-acetylhomoserine K01740 - 2.5.1.49 5.943e-199 630.0
XH2_k127_3287747_1 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 356.0
XH2_k127_329597_0 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 399.0
XH2_k127_329597_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009878 324.0
XH2_k127_329597_2 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000002031 229.0
XH2_k127_329597_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000001392 207.0
XH2_k127_329597_4 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.00000000000000000000000000000000000000000000000000004583 194.0
XH2_k127_329597_5 signal sequence binding - - - 0.000000000000000000000000000000002389 138.0
XH2_k127_3306417_0 Methyltransferase K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 357.0
XH2_k127_3306417_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 342.0
XH2_k127_3306417_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 308.0
XH2_k127_3306417_3 Beta-lactamase enzyme family K07262 - - 0.00000000000000000000000000485 111.0
XH2_k127_3306417_4 Domain of unknown function (DUF3390) K18929 - - 0.0000000000005159 70.0
XH2_k127_3343264_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 3.045e-210 662.0
XH2_k127_3343264_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000004862 226.0
XH2_k127_3343264_2 Pili and flagellar-assembly chaperone, PapD N-terminal domain K07346 - - 0.00000000000000000000000000000000000000002552 161.0
XH2_k127_3343264_3 Spore Coat Protein U domain - - - 0.00000000000000000000000000000008285 130.0
XH2_k127_3363626_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 552.0
XH2_k127_3363626_1 PFAM Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 332.0
XH2_k127_3363626_2 Dolichyl-phosphate-mannose-protein mannosyltransferase K00786 - - 0.0000000000000000000000000000000000001411 147.0
XH2_k127_3363626_3 PFAM GtrA family protein - - - 0.000000000000000000009422 103.0
XH2_k127_3464118_0 cytochrome d1 heme K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 576.0
XH2_k127_3464118_1 radical SAM protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 370.0
XH2_k127_3464118_2 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 352.0
XH2_k127_3464118_3 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 260.0
XH2_k127_3464118_4 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000006418 195.0
XH2_k127_3464118_5 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.000000000000000000000000054 108.0
XH2_k127_3467399_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 549.0
XH2_k127_3467399_1 Required for insertion of 4Fe-4S clusters K15724 - - 0.00000000000000000000000000000000000000000000000000000008026 201.0
XH2_k127_3467399_2 - - - - 0.00000000000000000000000000000000000000000000000000003935 196.0
XH2_k127_3467399_3 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000000000009522 185.0
XH2_k127_3467399_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000001933 79.0
XH2_k127_3467399_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000001115 62.0
XH2_k127_3467943_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 9.833e-246 771.0
XH2_k127_3467943_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 437.0
XH2_k127_3467943_2 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 357.0
XH2_k127_3467943_3 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 324.0
XH2_k127_3467943_4 Putative regulatory protein - - - 0.000000000000000000000000000001357 123.0
XH2_k127_3484283_0 SMART CBS domain containing protein K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 614.0
XH2_k127_3484283_1 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 463.0
XH2_k127_3484283_2 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 388.0
XH2_k127_3484283_3 response regulator K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 340.0
XH2_k127_3484283_4 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000001012 160.0
XH2_k127_3484283_5 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000009215 107.0
XH2_k127_3485664_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.394e-206 662.0
XH2_k127_3485847_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1195.0
XH2_k127_3485847_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1126.0
XH2_k127_3485847_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008292 262.0
XH2_k127_3485847_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000009994 227.0
XH2_k127_3490075_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 493.0
XH2_k127_3490075_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 418.0
XH2_k127_3490075_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 323.0
XH2_k127_3490075_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000375 280.0
XH2_k127_3490075_4 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000000000002323 152.0
XH2_k127_3490777_0 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 454.0
XH2_k127_3490777_1 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 298.0
XH2_k127_3490777_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000006162 140.0
XH2_k127_3556812_0 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 376.0
XH2_k127_3556812_1 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000000000000006293 162.0
XH2_k127_3556812_2 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000001102 163.0
XH2_k127_3568984_0 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000000000000000000000000000000000000000169 213.0
XH2_k127_3568984_1 Type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000009813 171.0
XH2_k127_3568984_2 Type II secretory pathway, pseudopilin - - - 0.000000000000000000000000000000000000000005877 169.0
XH2_k127_3568984_3 Secretin and TonB N terminus short domain K02453 - - 0.00000001108 62.0
XH2_k127_3572892_0 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000003535 190.0
XH2_k127_3586250_0 Domain of unknown function (DUF3400) - - - 0.0 1319.0
XH2_k127_3586250_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 345.0
XH2_k127_3586250_2 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 286.0
XH2_k127_3586250_3 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000000004382 185.0
XH2_k127_3593293_0 response regulator receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 332.0
XH2_k127_3593293_1 Histidine kinase K07637 - 2.7.13.3 0.00000000000000000000000000000000000000000000001224 175.0
XH2_k127_3593293_2 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000008895 147.0
XH2_k127_3593293_3 - - - - 0.0000000004917 64.0
XH2_k127_3605348_0 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 384.0
XH2_k127_3605348_1 carboxylase K01965 - 6.4.1.3 0.000000000000000000000000000000000000003972 147.0
XH2_k127_3631780_0 FeS assembly protein SufB K09014 - - 1.927e-212 664.0
XH2_k127_3631780_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 326.0
XH2_k127_3631780_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002271 171.0
XH2_k127_3631780_3 NnrU protein - - - 0.0000002499 53.0
XH2_k127_3641938_0 twitching motility protein K02670 - - 3.258e-201 631.0
XH2_k127_3641938_1 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 424.0
XH2_k127_3641938_2 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 288.0
XH2_k127_3647291_0 Enoyl-(Acyl carrier protein) reductase K16066 - 1.1.1.381 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 319.0
XH2_k127_3647291_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 297.0
XH2_k127_3647291_2 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000006487 187.0
XH2_k127_3662299_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 6.785e-256 797.0
XH2_k127_3662299_1 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.719e-221 691.0
XH2_k127_3662299_2 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 330.0
XH2_k127_3662299_3 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000801 266.0
XH2_k127_367931_0 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 319.0
XH2_k127_367931_1 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000002615 161.0
XH2_k127_3680157_0 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 483.0
XH2_k127_3680157_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000005781 209.0
XH2_k127_3680157_2 Cytochrome C' - - - 0.00003745 46.0
XH2_k127_3686283_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.214e-247 769.0
XH2_k127_368879_0 SAF - - - 9.444e-215 675.0
XH2_k127_368879_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 507.0
XH2_k127_368879_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 502.0
XH2_k127_368879_3 1-deoxy-D-xylulose-5-phosphate synthase K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 469.0
XH2_k127_368879_5 - - - - 0.00000000000000000000000000000001687 143.0
XH2_k127_3692052_0 polyphosphate kinase - - - 6.562e-232 728.0
XH2_k127_3692052_1 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 403.0
XH2_k127_3692052_2 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000173 104.0
XH2_k127_3697270_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 578.0
XH2_k127_3697270_1 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000001293 153.0
XH2_k127_3697270_2 - - - - 0.0000000000000000002224 93.0
XH2_k127_3714752_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 324.0
XH2_k127_3714752_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000005267 222.0
XH2_k127_3714752_2 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000000000000000000001389 99.0
XH2_k127_3715439_0 Ammonium Transporter K03320 - - 1.246e-223 700.0
XH2_k127_3715439_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 5.545e-219 685.0
XH2_k127_3715439_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 430.0
XH2_k127_3715439_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 425.0
XH2_k127_3715439_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000006932 166.0
XH2_k127_3721751_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 9.394e-246 776.0
XH2_k127_3721751_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 306.0
XH2_k127_3721751_2 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000003987 147.0
XH2_k127_3762589_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 487.0
XH2_k127_3762589_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000007281 128.0
XH2_k127_3777840_0 Cytochrome c bacterial - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 506.0
XH2_k127_3777840_1 Protein of unknown function DUF72 - - - 0.00000000000000001758 87.0
XH2_k127_3791878_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 6.238e-246 765.0
XH2_k127_3791878_1 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 325.0
XH2_k127_3791878_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000001177 151.0
XH2_k127_3791878_3 TIGRFAM MJ0042 family finger-like protein - - - 0.000000001146 66.0
XH2_k127_3799579_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.084e-223 698.0
XH2_k127_3799579_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 402.0
XH2_k127_3799579_2 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 357.0
XH2_k127_3799579_3 Cytochrome C1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 286.0
XH2_k127_3799579_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003427 280.0
XH2_k127_3799579_5 stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000000000007396 163.0
XH2_k127_3799579_6 dinuclear metal center protein, YbgI - - - 0.0000000000000000000000000000000000000005579 149.0
XH2_k127_380290_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001176 234.0
XH2_k127_380290_1 - - - - 0.00000000001317 77.0
XH2_k127_380969_0 Outer membrane protein beta-barrel family - - - 3.381e-282 889.0
XH2_k127_380969_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000131 147.0
XH2_k127_381445_0 Diguanylate cyclase - - - 2.13e-197 646.0
XH2_k127_381445_1 Histidine kinase K10125,K19661 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 356.0
XH2_k127_3827807_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 437.0
XH2_k127_3827807_1 lipid catabolic process - - - 0.0000000000000000000000000000000000000000000001218 186.0
XH2_k127_3827807_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000001516 67.0
XH2_k127_3827807_3 Acetyltransferase (GNAT) domain - - - 0.0000003589 57.0
XH2_k127_3827807_4 - - - - 0.000003188 52.0
XH2_k127_3847038_0 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 432.0
XH2_k127_3847038_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 431.0
XH2_k127_3847038_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
XH2_k127_3847038_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000002996 211.0
XH2_k127_3847038_4 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000003388 181.0
XH2_k127_3847038_5 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000005041 153.0
XH2_k127_3847038_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000003118 121.0
XH2_k127_3847038_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000003989 106.0
XH2_k127_3847263_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 395.0
XH2_k127_3847263_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 355.0
XH2_k127_3847263_2 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 324.0
XH2_k127_3847263_3 - - - - 0.00000000000000000000000000000001946 134.0
XH2_k127_3847263_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) - - - 0.00000000000001899 75.0
XH2_k127_3859517_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 1.264e-267 831.0
XH2_k127_3859517_1 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 451.0
XH2_k127_3859517_2 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000001768 148.0
XH2_k127_3876321_0 associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 539.0
XH2_k127_3876321_1 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 285.0
XH2_k127_3876321_2 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000002803 182.0
XH2_k127_3876321_3 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000003074 146.0
XH2_k127_3876321_4 SCP-2 sterol transfer family - - - 0.000000001665 59.0
XH2_k127_3876321_5 - - - - 0.0000002405 55.0
XH2_k127_3882063_0 PFAM Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 430.0
XH2_k127_3882063_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 388.0
XH2_k127_3882063_2 Iron-sulfur cluster assembly transcription factor IscR K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000006622 222.0
XH2_k127_3882063_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000001817 161.0
XH2_k127_3891832_0 Enoyl-(Acyl carrier protein) reductase K00059,K00076 - 1.1.1.100,1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 310.0
XH2_k127_3891832_1 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001778 247.0
XH2_k127_3891832_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000005066 188.0
XH2_k127_3891832_3 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000002315 137.0
XH2_k127_3911305_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1589.0
XH2_k127_3913197_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
XH2_k127_3913197_1 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.00000000000000000000000000000000000000004899 154.0
XH2_k127_3913197_2 ABC transporter, ATP-binding protein K02028,K02029 - 3.6.3.21 0.0000000000000000000000000000000000004119 146.0
XH2_k127_3928055_0 peptidase U62, modulator of DNA gyrase K03568 - - 1.877e-209 657.0
XH2_k127_3928055_1 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 602.0
XH2_k127_3928055_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000001536 129.0
XH2_k127_3928055_3 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000001587 117.0
XH2_k127_3928055_4 Dodecin K09165 - - 0.00000000000000000000002427 103.0
XH2_k127_3931386_0 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 346.0
XH2_k127_3931386_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000003009 160.0
XH2_k127_3931386_2 SpoIIAA-like - - - 0.00000000000000000000000000000000000002146 152.0
XH2_k127_3931386_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000132 102.0
XH2_k127_3945054_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.378e-248 774.0
XH2_k127_3945054_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 561.0
XH2_k127_3945054_2 PFAM MgtC SapB transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 501.0
XH2_k127_3945054_3 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 398.0
XH2_k127_3945054_4 GIY-YIG catalytic domain - - - 0.00000000000000000000000000000002954 128.0
XH2_k127_3953696_0 TonB-dependent receptor K02014 - - 8.855e-216 700.0
XH2_k127_3953696_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 381.0
XH2_k127_3953696_2 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000677 270.0
XH2_k127_3953696_3 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000842 261.0
XH2_k127_3953696_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000004496 206.0
XH2_k127_3953696_5 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000000000000029 192.0
XH2_k127_3953696_6 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000004722 166.0
XH2_k127_3954137_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000091 455.0
XH2_k127_3954137_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003708 248.0
XH2_k127_3954137_2 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000007655 185.0
XH2_k127_3954137_3 - - - - 0.0000000000000000000000000000000000000000000001484 184.0
XH2_k127_3954137_4 Virulence factor membrane-bound polymerase, C-terminal - - - 0.00000004144 59.0
XH2_k127_3954240_0 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 528.0
XH2_k127_3954240_1 Periplasmic solute binding protein K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 383.0
XH2_k127_3954240_2 ABC 3 transport family - - - 0.00000000000000000141 93.0
XH2_k127_3976551_0 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 587.0
XH2_k127_3976551_1 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000000005499 186.0
XH2_k127_3976551_2 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001326 144.0
XH2_k127_3976551_3 Outer membrane lipoprotein K07285 - - 0.000002576 55.0
XH2_k127_3981238_0 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 484.0
XH2_k127_3981238_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 370.0
XH2_k127_4011138_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 337.0
XH2_k127_4011138_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 310.0
XH2_k127_4011138_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000001079 179.0
XH2_k127_4064717_0 AcrB/AcrD/AcrF family K03296 - - 4.906e-209 664.0
XH2_k127_4064717_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 322.0
XH2_k127_4064717_2 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 327.0
XH2_k127_4077259_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.038e-208 654.0
XH2_k127_4077259_1 - - - - 0.000000000000000000000000000000000009117 141.0
XH2_k127_4079063_0 Outer membrane usher protein K07347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 533.0
XH2_k127_4079063_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 364.0
XH2_k127_4079063_2 Spore Coat - - - 0.0000000000000001687 88.0
XH2_k127_4100827_0 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 443.0
XH2_k127_4100827_1 Universal stress protein family - - - 0.0000000000000000000000000000000007669 135.0
XH2_k127_4100827_2 - - - - 0.0000000000000000000000000000000008978 136.0
XH2_k127_4101731_0 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001473 245.0
XH2_k127_4101731_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000007861 233.0
XH2_k127_4101731_2 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000000000009283 169.0
XH2_k127_4101731_3 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000004694 87.0
XH2_k127_4103052_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 461.0
XH2_k127_4103052_1 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000000000000000000007566 219.0
XH2_k127_4106090_0 ribonuclease II K01147 - 3.1.13.1 5.261e-246 774.0
XH2_k127_4106090_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 2.235e-228 714.0
XH2_k127_4106090_2 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 317.0
XH2_k127_4106090_3 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 271.0
XH2_k127_4106090_4 esterase K07000 - - 0.00000000000000000000000000000000000000000000000000000000004496 211.0
XH2_k127_4106090_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000001811 145.0
XH2_k127_4106090_6 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000001359 121.0
XH2_k127_4150874_0 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.00000000000000000000000000000001095 139.0
XH2_k127_4150874_1 Cysteine-rich secretory protein family - - - 0.00000000001137 71.0
XH2_k127_4165919_0 serine threonine protein kinase K12132 - 2.7.11.1 1.145e-261 818.0
XH2_k127_4172132_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 529.0
XH2_k127_4172132_1 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 423.0
XH2_k127_4172132_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 289.0
XH2_k127_4172132_3 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000001817 261.0
XH2_k127_4172132_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000003081 234.0
XH2_k127_4172132_5 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000000000000001078 115.0
XH2_k127_4187718_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 547.0
XH2_k127_4187718_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 487.0
XH2_k127_4187718_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 373.0
XH2_k127_4187718_3 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 355.0
XH2_k127_4187718_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000005562 176.0
XH2_k127_4187718_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000001708 127.0
XH2_k127_4189170_0 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 505.0
XH2_k127_4189170_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 282.0
XH2_k127_4189170_2 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000003244 159.0
XH2_k127_4189170_3 e3 binding domain K00627 - 2.3.1.12 0.000000000000000000000000000000116 129.0
XH2_k127_4234809_0 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 563.0
XH2_k127_4234809_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 345.0
XH2_k127_4234809_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000002742 205.0
XH2_k127_4234809_3 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000008069 201.0
XH2_k127_4235306_0 Transmembrane secretion effector - - - 1.271e-237 749.0
XH2_k127_4235306_1 AsmA family K07289,K07290 - - 0.000000000000000000000003435 109.0
XH2_k127_4238460_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.035e-205 647.0
XH2_k127_4238460_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 327.0
XH2_k127_4238460_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000004398 190.0
XH2_k127_4238460_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000001638 184.0
XH2_k127_4243551_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 502.0
XH2_k127_4243551_1 Bacterial lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 321.0
XH2_k127_4243551_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000004381 236.0
XH2_k127_4243551_3 FR47-like protein - - - 0.0000000000000000000000000000000000000000000001758 180.0
XH2_k127_4243551_4 SMART CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000000003442 167.0
XH2_k127_4253703_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 345.0
XH2_k127_4253703_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 308.0
XH2_k127_4253703_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005905 269.0
XH2_k127_4253703_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000009654 236.0
XH2_k127_4253703_4 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000000008165 140.0
XH2_k127_4253703_5 Heavy metal-associated domain protein K07213 - - 0.00000000000000000009444 90.0
XH2_k127_4286509_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 520.0
XH2_k127_4286509_1 Selenocysteine lyase K04127 - 5.1.1.17 0.000000000000000000000000000002103 132.0
XH2_k127_4290629_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.032e-251 781.0
XH2_k127_4290629_1 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 421.0
XH2_k127_4290629_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 327.0
XH2_k127_4290629_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000009795 210.0
XH2_k127_4290629_4 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000004717 194.0
XH2_k127_4290629_5 membrane - - - 0.0000000000000000000000004427 108.0
XH2_k127_4294859_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.581e-272 848.0
XH2_k127_4294859_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 606.0
XH2_k127_4294859_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 463.0
XH2_k127_4294859_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 381.0
XH2_k127_4294859_4 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 301.0
XH2_k127_4294859_5 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000005323 134.0
XH2_k127_4294859_6 Thioredoxin K05838 - - 0.00000000000000000005697 91.0
XH2_k127_4295623_0 surface antigen variable number repeat protein K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 554.0
XH2_k127_4295623_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 336.0
XH2_k127_4296943_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 7.9e-272 867.0
XH2_k127_4296943_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 442.0
XH2_k127_4296943_2 Glutaredoxin - - - 0.000000000000000000000004397 108.0
XH2_k127_4299158_0 PFAM Peptidase M16 K07263 - - 2.965e-211 664.0
XH2_k127_4299158_1 PFAM Peptidase M16 K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 535.0
XH2_k127_4299158_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000005181 240.0
XH2_k127_4299158_3 methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000003091 216.0
XH2_k127_4299158_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000005991 143.0
XH2_k127_4299158_5 protein kinase activity K08849 - 2.7.11.1 0.0008835 45.0
XH2_k127_4299698_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 1.52e-249 777.0
XH2_k127_4299698_1 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 368.0
XH2_k127_4321317_0 Heavy-metal-associated domain K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 485.0
XH2_k127_4321317_1 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005932 276.0
XH2_k127_4321317_2 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000004081 257.0
XH2_k127_4321317_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000005496 260.0
XH2_k127_4321317_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000002183 203.0
XH2_k127_4323407_0 Mechanosensitive ion channel K05802,K22051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 347.0
XH2_k127_4323407_1 PLD-like domain - - - 0.0000000000000000000000000000000000001253 144.0
XH2_k127_4325369_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 552.0
XH2_k127_4325369_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 386.0
XH2_k127_4325369_2 Integral membrane protein (DUF2244) - - - 0.000000000000000000000001715 109.0
XH2_k127_4338989_0 FAD binding domain K00394 - 1.8.99.2 4.033e-315 968.0
XH2_k127_4338989_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 8.082e-221 690.0
XH2_k127_4338989_2 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 301.0
XH2_k127_4338989_3 TPR repeat - - - 0.00000002354 62.0
XH2_k127_434212_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1650.0
XH2_k127_434212_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 538.0
XH2_k127_434212_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000001519 162.0
XH2_k127_4365019_0 radical SAM protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 494.0
XH2_k127_4365019_1 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
XH2_k127_4365019_2 AsnC-type helix-turn-helix domain - - - 0.000000000000000000151 88.0
XH2_k127_4373104_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1072.0
XH2_k127_4373104_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.016e-202 653.0
XH2_k127_4373104_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 353.0
XH2_k127_4373104_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
XH2_k127_4373104_4 RNA-binding protein K07574 - - 0.0000000000000000000000000001148 119.0
XH2_k127_4376341_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1250.0
XH2_k127_4376341_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 282.0
XH2_k127_4376341_2 Protein of unknown function (DUF2934) - - - 0.00000007044 56.0
XH2_k127_4390584_0 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 369.0
XH2_k127_4390584_1 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 335.0
XH2_k127_4390584_2 helix_turn_helix, Lux Regulon K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000872 272.0
XH2_k127_4390584_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009769 247.0
XH2_k127_4390584_4 - - - - 0.00000000000000009425 94.0
XH2_k127_4390584_5 Sulphur oxidation protein SoxZ K17226 - - 0.00000000002873 65.0
XH2_k127_4397838_0 Flavin reductase like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001502 274.0
XH2_k127_4397838_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000004934 182.0
XH2_k127_4397838_2 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000001838 139.0
XH2_k127_4397838_4 META domain - - - 0.0000000000000000000008909 106.0
XH2_k127_4397838_5 - - - - 0.0000003356 53.0
XH2_k127_4402669_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 383.0
XH2_k127_4402669_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 375.0
XH2_k127_4402669_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 331.0
XH2_k127_4402669_3 Glyoxalase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000007304 240.0
XH2_k127_4402669_4 Rubredoxin - - - 0.00000000000000000000000002807 122.0
XH2_k127_4402669_5 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000002397 63.0
XH2_k127_4402669_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000003775 54.0
XH2_k127_4414064_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 308.0
XH2_k127_4414064_1 Glycosyl transferase family 41 - - - 0.0000000000000003322 83.0
XH2_k127_4414064_2 Histone deacetylase domain - - - 0.000000006946 63.0
XH2_k127_4415985_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1016.0
XH2_k127_4415985_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 5.637e-202 638.0
XH2_k127_4415985_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 394.0
XH2_k127_4415985_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000003235 150.0
XH2_k127_4415985_4 Domain of unknown function (DUF4845) - - - 0.0000000000000000000001566 104.0
XH2_k127_4415985_5 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.0000000000000000000002858 98.0
XH2_k127_4419275_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 523.0
XH2_k127_4419275_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 464.0
XH2_k127_4419275_2 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001298 273.0
XH2_k127_4419275_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000334 252.0
XH2_k127_4419275_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000003284 246.0
XH2_k127_4419275_5 - - - - 0.0000000002389 66.0
XH2_k127_4420962_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 485.0
XH2_k127_4420962_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 402.0
XH2_k127_4420962_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003278 280.0
XH2_k127_4420962_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000003906 170.0
XH2_k127_4420962_4 Thioredoxin-like - - - 0.00000000000000000000000000000001055 143.0
XH2_k127_4420962_5 TCP-1/cpn60 chaperonin family K04077 - - 0.00000000000000000000006681 98.0
XH2_k127_4422387_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1030.0
XH2_k127_4422387_1 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004663 273.0
XH2_k127_4422387_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000003423 202.0
XH2_k127_4443312_0 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 350.0
XH2_k127_4443312_1 4Fe-4S dicluster domain K00124,K07307 - - 0.00000000000000000000000000000000000000000000001158 171.0
XH2_k127_4443312_2 - - - - 0.000000000000195 78.0
XH2_k127_4443312_3 - - - - 0.00000000007885 66.0
XH2_k127_4480574_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1068.0
XH2_k127_4488491_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1009.0
XH2_k127_4488491_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 414.0
XH2_k127_4488491_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 379.0
XH2_k127_4488491_3 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 387.0
XH2_k127_4488491_4 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 369.0
XH2_k127_4550525_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000008403 199.0
XH2_k127_4550525_1 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000001507 157.0
XH2_k127_4550525_2 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000005474 147.0
XH2_k127_4550525_3 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000008072 136.0
XH2_k127_4551533_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 303.0
XH2_k127_4551533_1 LemA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 289.0
XH2_k127_4551533_2 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003579 256.0
XH2_k127_4551533_3 Cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000001878 211.0
XH2_k127_4551533_4 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000008087 210.0
XH2_k127_4551533_5 17 kDa outer membrane surface antigen - - - 0.000001224 55.0
XH2_k127_4560867_0 His Kinase A (phosphoacceptor) domain K19661 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 459.0
XH2_k127_4560867_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 253.0
XH2_k127_4560867_2 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000000000000002105 209.0
XH2_k127_4562099_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 468.0
XH2_k127_4562099_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 331.0
XH2_k127_4562099_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 315.0
XH2_k127_4562099_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000009235 192.0
XH2_k127_4562099_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000226 155.0
XH2_k127_4562099_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000008997 112.0
XH2_k127_4569117_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 444.0
XH2_k127_4569117_1 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 411.0
XH2_k127_4569117_2 NapC/NirT cytochrome c family, N-terminal region K03532 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0020037,GO:0022900,GO:0031224,GO:0032991,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494,GO:1990204 - 0.000000000000000000000000000000000000001044 155.0
XH2_k127_4604781_0 Cysteine-rich domain - - - 1.625e-232 726.0
XH2_k127_4604781_1 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001514 260.0
XH2_k127_4604781_2 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001166 271.0
XH2_k127_4604781_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000613 218.0
XH2_k127_4611709_0 Belongs to the CarB family K01955 - 6.3.5.5 1.624e-271 839.0
XH2_k127_4611709_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 608.0
XH2_k127_4611709_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 404.0
XH2_k127_4611709_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000002186 238.0
XH2_k127_4611709_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000006896 222.0
XH2_k127_4611709_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000001303 140.0
XH2_k127_4624499_0 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
XH2_k127_4624499_1 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004431 250.0
XH2_k127_4624499_2 Phospholipid-binding protein K06910 - - 0.000000000000000000000202 96.0
XH2_k127_4624499_3 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000005654 78.0
XH2_k127_4624499_4 Lysin motif - - - 0.0002847 51.0
XH2_k127_4630216_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 437.0
XH2_k127_4630216_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 368.0
XH2_k127_4630216_2 (FHA) domain - - - 0.0000000000000000000000000000000000000000000000000518 180.0
XH2_k127_4651892_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.517e-254 786.0
XH2_k127_4651892_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.855e-239 755.0
XH2_k127_4651892_2 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 1.509e-221 708.0
XH2_k127_4651892_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
XH2_k127_4651892_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 289.0
XH2_k127_4651892_5 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001869 250.0
XH2_k127_4651892_6 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000006335 134.0
XH2_k127_4651892_7 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000000000000000001572 126.0
XH2_k127_4651892_8 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331,K03940 - 1.6.5.3,1.6.99.3 0.0000000000002312 73.0
XH2_k127_4656925_0 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 553.0
XH2_k127_4656925_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 344.0
XH2_k127_4656925_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090,K18916 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81,1.20.1.1 0.0000000000000000000000000000000000000000000003937 170.0
XH2_k127_4658551_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 4.042e-304 941.0
XH2_k127_4658551_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 306.0
XH2_k127_4658551_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000001045 179.0
XH2_k127_4665987_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.835e-198 628.0
XH2_k127_4665987_1 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 503.0
XH2_k127_4665987_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.0000000000000000000000000000000000000006862 150.0
XH2_k127_4665987_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000153 131.0
XH2_k127_4678919_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 533.0
XH2_k127_4678919_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 328.0
XH2_k127_4678919_2 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000002323 161.0
XH2_k127_4678919_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000007607 132.0
XH2_k127_4704578_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.0 1080.0
XH2_k127_4718466_0 FMN_bind - - - 2.324e-213 674.0
XH2_k127_4718466_1 Cytochrome C oxidase subunit II, periplasmic domain protein K00376 - 1.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000111 234.0
XH2_k127_4733325_0 Protein export membrane protein K07239 - - 5.964e-243 759.0
XH2_k127_4737229_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 468.0
XH2_k127_4737229_1 Divalent cation transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 465.0
XH2_k127_4737229_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000001679 187.0
XH2_k127_4737838_0 membrane protein, terc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 313.0
XH2_k127_4737838_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000005318 154.0
XH2_k127_4737838_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000003455 64.0
XH2_k127_4748284_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 524.0
XH2_k127_4748284_1 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000003048 109.0
XH2_k127_4748284_2 - - - - 0.0000000000000000000004027 104.0
XH2_k127_475327_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 509.0
XH2_k127_475327_1 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000002127 220.0
XH2_k127_475327_2 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000001677 66.0
XH2_k127_4770133_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 578.0
XH2_k127_4770133_1 glutamate synthase - - - 0.0000000000000000000000001048 106.0
XH2_k127_4770133_2 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 0.0000000000000000000001897 97.0
XH2_k127_4785299_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 586.0
XH2_k127_4785299_1 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 463.0
XH2_k127_4785299_2 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 389.0
XH2_k127_4785299_3 FeS assembly protein SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002523 274.0
XH2_k127_4785299_4 SUF system FeS assembly protein, NifU family K04488 - - 0.0000000000000000000000000000000000000000000000000000000004913 206.0
XH2_k127_4785299_5 Pfam:DUF59 - - - 0.000000000000000000000000000000000008359 146.0
XH2_k127_4845734_0 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 476.0
XH2_k127_4845734_1 Protein conserved in bacteria K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 433.0
XH2_k127_4845734_2 AMP-binding enzyme C-terminal domain K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 399.0
XH2_k127_4845734_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 388.0
XH2_k127_4845734_4 membrane transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 349.0
XH2_k127_4846874_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 460.0
XH2_k127_4846874_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 386.0
XH2_k127_4846874_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000001178 123.0
XH2_k127_4853514_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000006093 239.0
XH2_k127_4853514_1 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000004596 201.0
XH2_k127_4853514_2 Protein tyrosine kinase - - - 0.0000000000000000000000003768 109.0
XH2_k127_4862237_0 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 463.0
XH2_k127_4862237_1 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000001845 177.0
XH2_k127_4862237_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000006958 126.0
XH2_k127_4862237_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0001516 48.0
XH2_k127_4865836_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 515.0
XH2_k127_4865836_1 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 509.0
XH2_k127_4865836_2 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 393.0
XH2_k127_4865836_3 coenzyme F390 K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 349.0
XH2_k127_4865836_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 357.0
XH2_k127_4865836_5 PFAM FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000001159 238.0
XH2_k127_4865836_7 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000002195 143.0
XH2_k127_4894643_0 Two component regulator three Y domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005951 266.0
XH2_k127_4908686_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002178 257.0
XH2_k127_4908686_1 Peptidase S24-like - - - 0.0000000000000000000000000000000005805 134.0
XH2_k127_4908686_2 - - - - 0.000000000000000001499 92.0
XH2_k127_4908686_3 - - - - 0.00000000000001506 81.0
XH2_k127_4920113_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 492.0
XH2_k127_4920113_1 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 426.0
XH2_k127_4920113_2 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000012 246.0
XH2_k127_4920113_3 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000005027 184.0
XH2_k127_4934112_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 529.0
XH2_k127_4934112_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 294.0
XH2_k127_4934112_2 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000002209 239.0
XH2_k127_4934112_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000163 235.0
XH2_k127_4934112_4 PFAM thiamineS protein - - - 0.000000000000000000000002189 116.0
XH2_k127_4934112_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000007507 102.0
XH2_k127_4934213_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 578.0
XH2_k127_4934213_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003763 271.0
XH2_k127_4934213_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002417 276.0
XH2_k127_4934213_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002743 235.0
XH2_k127_4934213_4 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000001655 224.0
XH2_k127_4934213_5 Protein of unknown function (DUF2788) - - - 0.000000000000000000000006778 102.0
XH2_k127_4941677_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 538.0
XH2_k127_4941677_1 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 321.0
XH2_k127_4941677_2 branched-chain amino acid K01995 - - 0.00000000000000000000000000000000000000009687 151.0
XH2_k127_4941677_3 - - - - 0.000000003998 60.0
XH2_k127_4955546_0 Molecular chaperone. Has ATPase activity K04079 - - 9.47e-287 903.0
XH2_k127_4955546_1 GGDEF domain - - - 1.995e-215 685.0
XH2_k127_4955546_2 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 303.0
XH2_k127_4955546_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000003422 237.0
XH2_k127_4955546_4 - - - - 0.00000001803 58.0
XH2_k127_4957950_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 6.877e-194 609.0
XH2_k127_4957950_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 595.0
XH2_k127_4957950_2 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000293 261.0
XH2_k127_4957950_3 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000000005626 202.0
XH2_k127_4957950_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000012 110.0
XH2_k127_4986322_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 377.0
XH2_k127_4986322_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 252.0
XH2_k127_4986322_2 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000000000000000000000003173 165.0
XH2_k127_4986322_3 Protein of unknown function DUF86 - - - 0.0000000000000000000000001678 113.0
XH2_k127_502929_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 350.0
XH2_k127_502929_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000005089 185.0
XH2_k127_502929_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000005094 141.0
XH2_k127_5063971_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000001723 141.0
XH2_k127_5063971_1 Nitrate reductase delta subunit - - - 0.0000000000002254 79.0
XH2_k127_5063971_2 4Fe-4S dicluster domain - - - 0.0000000007258 65.0
XH2_k127_5078995_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1441.0
XH2_k127_5078995_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 9.18e-236 740.0
XH2_k127_5078995_2 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 400.0
XH2_k127_5078995_3 PFAM permease YjgP YjgQ family protein K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 379.0
XH2_k127_5078995_4 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000001564 202.0
XH2_k127_5078995_5 RDD family - - - 0.000000000000000000000000000000005825 130.0
XH2_k127_5078995_6 FecR protein - - - 0.00008138 53.0
XH2_k127_510567_0 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002329 283.0
XH2_k127_510567_1 - - - - 0.0000000000000000002358 99.0
XH2_k127_5147091_0 Sulfatase K01135 - 3.1.6.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001425 267.0
XH2_k127_5147091_1 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000003991 127.0
XH2_k127_5164147_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 608.0
XH2_k127_5164147_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 465.0
XH2_k127_5164147_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 479.0
XH2_k127_5164147_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002431 255.0
XH2_k127_5190262_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 367.0
XH2_k127_5190262_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
XH2_k127_5190262_2 - - - - 0.00000000000000000008286 94.0
XH2_k127_5195649_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 443.0
XH2_k127_5195649_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 288.0
XH2_k127_5195649_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000003669 65.0
XH2_k127_5215399_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.642e-205 665.0
XH2_k127_5215399_1 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007963 371.0
XH2_k127_5215399_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000005133 215.0
XH2_k127_5215399_3 PFAM Cytochrome C - - - 0.00000000000000000000000115 105.0
XH2_k127_5220127_0 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 406.0
XH2_k127_5220127_1 S4 RNA-binding domain K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 377.0
XH2_k127_5220127_2 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 400.0
XH2_k127_5220127_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000004706 145.0
XH2_k127_5222437_0 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 541.0
XH2_k127_5222437_1 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 360.0
XH2_k127_5222437_2 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 328.0
XH2_k127_5222437_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000002927 64.0
XH2_k127_5248095_0 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000004613 247.0
XH2_k127_5248095_1 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000002167 231.0
XH2_k127_5248095_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000586 141.0
XH2_k127_5258630_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.551e-234 744.0
XH2_k127_5258630_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 517.0
XH2_k127_5258630_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 349.0
XH2_k127_5258630_3 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003499 268.0
XH2_k127_5258630_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000006231 202.0
XH2_k127_5258630_5 Protein of unknown function DUF45 K07043 - - 0.0000000000006261 70.0
XH2_k127_5265227_0 PFAM Alanine dehydrogenase PNT, C-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000127 244.0
XH2_k127_5265227_1 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000002354 224.0
XH2_k127_5265227_2 His Kinase A (phosphoacceptor) domain K11527 - 2.7.13.3 0.000000000000000000000000000000000000000001728 173.0
XH2_k127_5265227_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000462 79.0
XH2_k127_5265227_4 YMGG-like Gly-zipper - - - 0.0000000003442 63.0
XH2_k127_5289807_0 Pfam Fatty acid - - - 0.0 1037.0
XH2_k127_5289807_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000001271 196.0
XH2_k127_5301487_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 596.0
XH2_k127_5301487_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 554.0
XH2_k127_5301487_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 385.0
XH2_k127_5301487_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 295.0
XH2_k127_5301487_4 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000009049 217.0
XH2_k127_5322450_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.0 1028.0
XH2_k127_5322450_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001172 261.0
XH2_k127_5322450_2 - - - - 0.0000000000000000000000000007722 120.0
XH2_k127_5322450_3 YMGG-like Gly-zipper - - - 0.00000000000000001933 83.0
XH2_k127_5322450_4 Outer membrane lipoprotein Blc K03098 - - 0.00000000003873 72.0
XH2_k127_5323127_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1135.0
XH2_k127_5323127_1 - - - - 0.0000000000000003815 79.0
XH2_k127_5325778_0 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 414.0
XH2_k127_5325778_1 squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 365.0
XH2_k127_5325778_2 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000006952 158.0
XH2_k127_5325778_3 - - - - 0.000002042 53.0
XH2_k127_5336309_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 464.0
XH2_k127_5336309_1 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 321.0
XH2_k127_5336309_2 Recombinase zinc beta ribbon domain - - - 0.0000000000284 66.0
XH2_k127_5414715_0 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 343.0
XH2_k127_5414715_1 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000008666 179.0
XH2_k127_5414715_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000001063 145.0
XH2_k127_5414715_3 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000005097 146.0
XH2_k127_5414715_4 - - - - 0.00001909 53.0
XH2_k127_5437556_0 small subunit K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 455.0
XH2_k127_5437556_1 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 377.0
XH2_k127_5437556_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001203 230.0
XH2_k127_5437556_3 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000000000000000008691 170.0
XH2_k127_5437556_4 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000000000000000001512 153.0
XH2_k127_5458089_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 609.0
XH2_k127_5458089_1 Divalent cation transporter - - - 0.0000000000002633 70.0
XH2_k127_5483669_0 Sigma-54 interaction domain - - - 2.2e-200 634.0
XH2_k127_5483669_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 363.0
XH2_k127_5483669_2 Protein of unknown function DUF72 - - - 0.000000002844 70.0
XH2_k127_5493957_0 NADPH-dependent glutamate synthase beta - - - 4.456e-308 955.0
XH2_k127_5493957_1 Fe-S oxidoreductase K21834 - - 9.408e-244 756.0
XH2_k127_5495769_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.908e-306 951.0
XH2_k127_5495769_1 DNA polymerase III K02342 - 2.7.7.7 3.586e-238 756.0
XH2_k127_5495769_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 2.235e-218 695.0
XH2_k127_5495769_3 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
XH2_k127_5495769_4 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000001231 177.0
XH2_k127_5495769_5 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000667 168.0
XH2_k127_5495769_6 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000009364 132.0
XH2_k127_5495769_7 - - - - 0.0000000000000000001967 92.0
XH2_k127_5556225_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1294.0
XH2_k127_5556225_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 367.0
XH2_k127_5556225_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000007778 143.0
XH2_k127_5556225_3 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000008708 116.0
XH2_k127_5556225_4 Permease MlaE K02066 - - 0.0000000000000000003389 93.0
XH2_k127_5606825_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 471.0
XH2_k127_5606825_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00003438 51.0
XH2_k127_5608983_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 3.687e-204 641.0
XH2_k127_5608983_1 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000001669 168.0
XH2_k127_5608983_2 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000002536 78.0
XH2_k127_5676919_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.563e-209 666.0
XH2_k127_5676919_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 449.0
XH2_k127_5676919_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 287.0
XH2_k127_5676919_3 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000003646 199.0
XH2_k127_5676919_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000007553 124.0
XH2_k127_5676919_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000034 115.0
XH2_k127_5676919_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000004937 101.0
XH2_k127_5680861_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001017 278.0
XH2_k127_5680861_1 - - - - 0.0000000000000000000000000000000000000000000000000002609 192.0
XH2_k127_5680861_2 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000001325 140.0
XH2_k127_5686047_0 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 509.0
XH2_k127_5686047_1 Peptidase family M28 - - - 0.000000004361 60.0
XH2_k127_5695214_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.723e-318 989.0
XH2_k127_5695214_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 5.815e-242 757.0
XH2_k127_5695214_10 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000000000003961 215.0
XH2_k127_5695214_11 Small MutS-related domain - - - 0.00000000000000000000000000000000000000000000000000001205 194.0
XH2_k127_5695214_12 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000007322 173.0
XH2_k127_5695214_13 Prokaryotic N-terminal methylation motif K10925 - - 0.0000000001662 70.0
XH2_k127_5695214_2 AAA ATPase central domain protein K07478 - - 5.855e-220 688.0
XH2_k127_5695214_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.333e-213 669.0
XH2_k127_5695214_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 530.0
XH2_k127_5695214_5 Helix-turn-helix type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 349.0
XH2_k127_5695214_6 Methyltransferase FkbM family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 321.0
XH2_k127_5695214_7 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 248.0
XH2_k127_5695214_8 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000008837 235.0
XH2_k127_5695214_9 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000003982 203.0
XH2_k127_5707871_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 4.65e-284 890.0
XH2_k127_5707871_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 509.0
XH2_k127_5707871_2 - - - - 0.00000000000000000000000000000000000000000000000000002488 196.0
XH2_k127_5707871_3 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000003232 145.0
XH2_k127_5738418_0 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 323.0
XH2_k127_575787_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 532.0
XH2_k127_575787_1 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 354.0
XH2_k127_575787_2 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000005126 59.0
XH2_k127_5769774_0 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 335.0
XH2_k127_5769774_1 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 319.0
XH2_k127_5769774_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001018 264.0
XH2_k127_5769774_3 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000009793 213.0
XH2_k127_5769774_4 Rhodanese-like domain - - - 0.000000000000000000000000005969 124.0
XH2_k127_5769774_5 Bacterial SH3 domain - - - 0.00000000000000001253 93.0
XH2_k127_5798855_0 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 304.0
XH2_k127_5798855_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000001236 194.0
XH2_k127_5800408_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 456.0
XH2_k127_5800408_1 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 341.0
XH2_k127_5800408_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000001616 151.0
XH2_k127_5914030_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 301.0
XH2_k127_5916856_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.687e-207 651.0
XH2_k127_5916856_1 PFAM multicopper oxidase type 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 598.0
XH2_k127_5916856_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 529.0
XH2_k127_5916856_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 319.0
XH2_k127_5916856_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000524 174.0
XH2_k127_5932952_0 Participates in both transcription termination and antitermination K02600 - - 1.63e-233 730.0
XH2_k127_5932952_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000005971 161.0
XH2_k127_5975557_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.397e-264 819.0
XH2_k127_5975557_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 426.0
XH2_k127_5975557_2 Major facilitator Superfamily - - - 0.0000000000942 70.0
XH2_k127_5990838_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 570.0
XH2_k127_5990838_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00001747 57.0
XH2_k127_5998180_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.587e-317 987.0
XH2_k127_5998180_1 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 371.0
XH2_k127_5998180_2 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002349 272.0
XH2_k127_5998180_3 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000001744 190.0
XH2_k127_6047462_0 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003253 267.0
XH2_k127_6047462_1 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
XH2_k127_6047462_2 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000001428 189.0
XH2_k127_6047462_3 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000005834 197.0
XH2_k127_6047462_4 Rubredoxin - - - 0.00000000000000000000000004721 118.0
XH2_k127_6047735_0 Malic enzyme K00029 - 1.1.1.40 0.0 1012.0
XH2_k127_6047735_1 His Kinase A (phosphoacceptor) domain K11711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 463.0
XH2_k127_6047735_2 response regulator K11712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002032 258.0
XH2_k127_6047735_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000001143 99.0
XH2_k127_6072330_1 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000009031 184.0
XH2_k127_6102625_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 1.633e-201 640.0
XH2_k127_6102625_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 601.0
XH2_k127_6102625_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 425.0
XH2_k127_6102625_3 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 253.0
XH2_k127_6102625_4 Phasin protein - - - 0.00000000000000000000000000000000000000002618 158.0
XH2_k127_6116511_0 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 503.0
XH2_k127_6116511_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 362.0
XH2_k127_6116511_2 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000000000000001017 206.0
XH2_k127_6116511_3 - - - - 0.0000000000000000000000000000000000000000000000000000008119 201.0
XH2_k127_6116511_4 Cas6 Crispr - - - 0.000000000000000000000000000000000000000000000003394 183.0
XH2_k127_6116511_5 DsrC like protein - - - 0.000000000000000000000000000000000000000000003835 165.0
XH2_k127_6116511_6 - - - - 0.0000000000000000000008502 97.0
XH2_k127_6116511_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000618 63.0
XH2_k127_611812_0 - - - - 0.0000001677 64.0
XH2_k127_6119343_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.783e-208 654.0
XH2_k127_6119343_1 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000696 389.0
XH2_k127_6119343_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000009527 51.0
XH2_k127_6137735_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 577.0
XH2_k127_6137735_1 TIGRFAM TonB family protein K03646 - - 0.0000000000000000000000000000000000275 141.0
XH2_k127_613797_0 TIGRFAM ATP-dependent Clp protease, ATP-binding subunit clpA K03694 - - 0.0 1187.0
XH2_k127_613797_1 sulfide dehydrogenase K05301 - 1.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 408.0
XH2_k127_613797_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 324.0
XH2_k127_613797_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000009197 225.0
XH2_k127_613797_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000582 159.0
XH2_k127_613797_5 cytochrome - - - 0.00000000000000009872 84.0
XH2_k127_6167393_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.768e-306 944.0
XH2_k127_6169553_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 438.0
XH2_k127_6169553_1 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 427.0
XH2_k127_6169553_2 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 407.0
XH2_k127_6169553_3 NosL K19342 - - 0.0000000000000000000000000000000000000000000000000000000000001212 229.0
XH2_k127_6169553_4 - - - - 0.0000000000000000000000000000001841 130.0
XH2_k127_6169553_5 - - - - 0.000000000000000000000007601 104.0
XH2_k127_6169553_6 - - - - 0.0000000000000000000005942 98.0
XH2_k127_6178791_0 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 538.0
XH2_k127_6178791_1 TIGRFAM TIGR03032 family protein - - - 0.000000000002371 76.0
XH2_k127_6222036_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 425.0
XH2_k127_6222036_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000003116 110.0
XH2_k127_6240493_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 5.005e-209 665.0
XH2_k127_6240493_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 2.612e-195 618.0
XH2_k127_6240493_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 577.0
XH2_k127_6240493_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000001443 163.0
XH2_k127_6253300_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1373.0
XH2_k127_6253300_1 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000001518 232.0
XH2_k127_6253300_2 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000000000002047 221.0
XH2_k127_6260340_0 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.881e-257 801.0
XH2_k127_6260340_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 2.596e-209 660.0
XH2_k127_6260340_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 424.0
XH2_k127_6260340_3 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 356.0
XH2_k127_6260340_4 Belongs to the enoyl-CoA hydratase isomerase family K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000492 263.0
XH2_k127_6260340_5 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000009345 244.0
XH2_k127_6281023_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.707e-227 708.0
XH2_k127_6281023_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 567.0
XH2_k127_6281023_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 344.0
XH2_k127_6281023_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000006419 229.0
XH2_k127_6281023_4 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000002801 207.0
XH2_k127_6281023_5 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000005787 206.0
XH2_k127_6281023_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000006174 145.0
XH2_k127_6281023_7 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.0000000000000000000000000000000000003604 141.0
XH2_k127_6281023_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000006109 71.0
XH2_k127_630293_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.252e-194 612.0
XH2_k127_630293_1 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 372.0
XH2_k127_630293_2 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 297.0
XH2_k127_6381164_0 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 559.0
XH2_k127_6381164_1 Sulfate ABC transporter inner membrane subunit CysW K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 466.0
XH2_k127_6381164_2 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 468.0
XH2_k127_6381164_3 esterase of the alpha beta hydrolase fold K07002 - - 0.000000000000000000000000000000000000000000000000000000000000000000007987 244.0
XH2_k127_6381164_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000003156 186.0
XH2_k127_6381164_5 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000001226 125.0
XH2_k127_6391352_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 396.0
XH2_k127_6391352_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 367.0
XH2_k127_6391352_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 341.0
XH2_k127_6391352_3 plastoquinol--plastocyanin reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
XH2_k127_6455369_0 ABC transporter K15738 - - 4.536e-229 718.0
XH2_k127_6455369_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
XH2_k127_6455369_2 Bile acid K03453 - - 0.0000000000001549 73.0
XH2_k127_6467119_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.501e-235 737.0
XH2_k127_6467119_1 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000006104 212.0
XH2_k127_6467119_2 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000008492 157.0
XH2_k127_6467119_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000003305 77.0
XH2_k127_646937_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 472.0
XH2_k127_646937_1 - - - - 0.000000000000000000000009603 110.0
XH2_k127_649576_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 383.0
XH2_k127_649576_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 311.0
XH2_k127_649576_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000002705 141.0
XH2_k127_649576_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000001779 107.0
XH2_k127_649576_12 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000002795 94.0
XH2_k127_649576_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002987 257.0
XH2_k127_649576_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000007658 226.0
XH2_k127_649576_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000000002281 222.0
XH2_k127_649576_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000003055 218.0
XH2_k127_649576_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000003957 173.0
XH2_k127_649576_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000005666 169.0
XH2_k127_649576_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000001972 141.0
XH2_k127_649576_9 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000002162 144.0
XH2_k127_6539124_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 353.0
XH2_k127_6539124_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
XH2_k127_6539124_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 290.0
XH2_k127_6539124_3 - - - - 0.00000000000000000000000000000000000000024 154.0
XH2_k127_6539124_4 - - - - 0.000000000000000000002762 96.0
XH2_k127_6539124_5 - - - - 0.000000000000000000003344 102.0
XH2_k127_6543919_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000003105 235.0
XH2_k127_6543919_1 Protein of unknown function (DUF3301) - - - 0.00000000000000000001188 100.0
XH2_k127_6546553_0 HD domain K07814,K13815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 405.0
XH2_k127_6546553_1 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.0000000000000000000000000000000000008373 142.0
XH2_k127_6550123_0 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007802 343.0
XH2_k127_6550123_1 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 317.0
XH2_k127_6550123_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 303.0
XH2_k127_6550123_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000002464 224.0
XH2_k127_6550123_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000001919 158.0
XH2_k127_6616081_0 Animal haem peroxidase - - - 0.00000000000000000000000000000000000000000000000123 177.0
XH2_k127_6616081_1 SdpI/YhfL protein family - - - 0.0000000000000003432 87.0
XH2_k127_6616081_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03789,K03790,K03896 - 2.3.1.102,2.3.1.128 0.0000003719 60.0
XH2_k127_6616081_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00007062 45.0
XH2_k127_6630044_0 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001861 248.0
XH2_k127_6630044_1 - - - - 0.0000000000000000000000000000000000000000000000000000003611 207.0
XH2_k127_6630044_2 Cytochrome c mono- and diheme variants - - - 0.00000001305 59.0
XH2_k127_6630044_3 GXGXG motif K00202 - 1.2.7.12 0.00000006915 55.0
XH2_k127_6633142_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 1.343e-221 698.0
XH2_k127_6646438_0 acyl-CoA dehydrogenase K06445 - - 0.0 1065.0
XH2_k127_6646438_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000003719 229.0
XH2_k127_6646438_2 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 0.000000000000000815 78.0
XH2_k127_6646438_3 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000002037 66.0
XH2_k127_666065_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 5.216e-284 884.0
XH2_k127_6665069_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 596.0
XH2_k127_6665069_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 550.0
XH2_k127_6665069_2 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 304.0
XH2_k127_6675529_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.078e-253 788.0
XH2_k127_6675529_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 5.327e-195 613.0
XH2_k127_6675529_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 530.0
XH2_k127_6675529_3 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 470.0
XH2_k127_6675529_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 361.0
XH2_k127_6675529_5 pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000415 154.0
XH2_k127_6731176_0 ABC transporter K01999 - - 8.814e-201 631.0
XH2_k127_6731176_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 406.0
XH2_k127_6731176_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 403.0
XH2_k127_6731176_3 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008185 394.0
XH2_k127_6731176_4 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.00000000000000000000000000000000000000000000000002891 183.0
XH2_k127_6731176_5 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000003546 79.0
XH2_k127_6763012_0 Multicopper oxidase K22349 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 386.0
XH2_k127_6763012_1 Signal transduction histidine kinase K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
XH2_k127_6763012_2 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000001962 183.0
XH2_k127_6763012_3 FIST N domain - - - 0.000000000000000000000000000000819 123.0
XH2_k127_6775065_0 Mechanosensitive ion channel K05802,K22051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 385.0
XH2_k127_6775065_1 PLD-like domain - - - 0.000000000000000000000000000000000005823 139.0
XH2_k127_6821690_0 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 429.0
XH2_k127_6821690_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 368.0
XH2_k127_6844830_0 Malic enzyme K00029 - 1.1.1.40 2.97e-303 941.0
XH2_k127_6852599_0 extracellular solute-binding protein - - - 0.0 1034.0
XH2_k127_6852599_1 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 598.0
XH2_k127_6852599_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 426.0
XH2_k127_6852599_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000001168 120.0
XH2_k127_688085_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 474.0
XH2_k127_688085_1 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000005618 182.0
XH2_k127_6891861_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1007.0
XH2_k127_6891861_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 389.0
XH2_k127_6891861_2 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000000008644 199.0
XH2_k127_6891861_3 - - - - 0.00000000000000000000000000000000000000000000000006242 182.0
XH2_k127_6891861_4 - - - - 0.00000000000001763 79.0
XH2_k127_7005580_0 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.0 1165.0
XH2_k127_7005580_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 552.0
XH2_k127_7005580_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 327.0
XH2_k127_7005580_3 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000205 282.0
XH2_k127_7016107_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 519.0
XH2_k127_7016107_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 519.0
XH2_k127_7016107_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 357.0
XH2_k127_7016107_3 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000003748 238.0
XH2_k127_7016107_4 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000003138 167.0
XH2_k127_701795_0 cytochrome - - - 1.859e-255 798.0
XH2_k127_701795_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 591.0
XH2_k127_701795_2 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 316.0
XH2_k127_701795_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 302.0
XH2_k127_7040136_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 572.0
XH2_k127_7040136_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 332.0
XH2_k127_7069694_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005778 248.0
XH2_k127_7114531_0 Tripartite tricarboxylate transporter family receptor K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 522.0
XH2_k127_7114531_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 298.0
XH2_k127_7114531_2 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002137 237.0
XH2_k127_7114531_3 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000007836 148.0
XH2_k127_7147418_0 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 346.0
XH2_k127_7147418_1 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000001227 216.0
XH2_k127_7147418_2 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000004618 53.0
XH2_k127_7150140_0 PFAM FMN-binding domain protein K19339 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 570.0
XH2_k127_7150140_1 - - - - 0.00000000000000000000000000000000000000000000277 173.0
XH2_k127_7150140_2 - - - - 0.000000000000001715 83.0
XH2_k127_7150140_3 GumN family K09973 - - 0.000000002223 60.0
XH2_k127_7161248_0 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 306.0
XH2_k127_7161248_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000001055 216.0
XH2_k127_7168439_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 577.0
XH2_k127_7168439_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000002494 253.0
XH2_k127_7168439_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000002101 182.0
XH2_k127_7168439_3 Trypsin - - - 0.0000000000000000000000000000000000000000000000407 186.0
XH2_k127_7168439_4 - - - - 0.00000000000000000000000000000000000000000000007892 173.0
XH2_k127_7168439_5 DsrC like protein - - - 0.00000000000000000000000000000000000001723 152.0
XH2_k127_7168439_6 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000003929 143.0
XH2_k127_7168439_7 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000003708 119.0
XH2_k127_7168439_8 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000488 106.0
XH2_k127_7168439_9 Bacterial protein of unknown function (DUF853) K06915 - - 0.00000006579 54.0
XH2_k127_7181013_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.957e-217 679.0
XH2_k127_7181013_1 modulator of DNA gyrase K03592 - - 2.294e-199 629.0
XH2_k127_7181013_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 607.0
XH2_k127_7181013_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 503.0
XH2_k127_7181013_4 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 338.0
XH2_k127_7181013_5 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 302.0
XH2_k127_7181013_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
XH2_k127_7181013_7 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000006035 218.0
XH2_k127_7181013_8 - - - - 0.00000000000000000000000000000000000000000000002497 179.0
XH2_k127_7181013_9 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000001006 166.0
XH2_k127_7200509_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 586.0
XH2_k127_7200509_1 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000001377 150.0
XH2_k127_7221017_0 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 539.0
XH2_k127_7221017_1 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 520.0
XH2_k127_7221017_2 - - - - 0.0000000000000000000000000000000002899 136.0
XH2_k127_7221017_3 - - - - 0.00000000000000000381 84.0
XH2_k127_7234730_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 561.0
XH2_k127_7234730_1 lipopolysaccharide heptosyltransferase I K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000001909 239.0
XH2_k127_7234730_2 PIN domain - - - 0.0000000000000000000000000000000000000000000001277 171.0
XH2_k127_7234730_3 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000003831 128.0
XH2_k127_7234730_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000001767 119.0
XH2_k127_7234730_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000002949 107.0
XH2_k127_7283381_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.505e-196 620.0
XH2_k127_7283381_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 435.0
XH2_k127_7283381_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 424.0
XH2_k127_7283381_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 402.0
XH2_k127_7283381_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 372.0
XH2_k127_7283381_5 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001387 247.0
XH2_k127_7283381_6 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000002797 220.0
XH2_k127_7283381_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000005336 134.0
XH2_k127_7283381_8 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000002243 121.0
XH2_k127_7283381_9 response to antibiotic K07122 - - 0.0000000000000001374 82.0
XH2_k127_7287864_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 9.555e-270 840.0
XH2_k127_7287864_1 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 330.0
XH2_k127_7287864_2 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.0000000000000000002808 92.0
XH2_k127_7287864_3 - K19168 - - 0.0000001493 54.0
XH2_k127_7308844_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.746e-198 630.0
XH2_k127_7308844_1 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 431.0
XH2_k127_7308844_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 421.0
XH2_k127_7308844_3 PFAM AFG1-family ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 396.0
XH2_k127_7308844_4 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000006311 257.0
XH2_k127_7319857_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000005435 243.0
XH2_k127_7319857_1 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003356 243.0
XH2_k127_7319857_2 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000006862 146.0
XH2_k127_7362953_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 425.0
XH2_k127_7362953_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000009025 235.0
XH2_k127_7362953_2 QueF-like protein - - - 0.0000000000000331 86.0
XH2_k127_7362953_3 of the drug metabolite transporter (DMT) superfamily - - - 0.00008235 46.0
XH2_k127_7368689_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 6.45e-301 931.0
XH2_k127_7368689_1 homoserine dehydrogenase K00003 - 1.1.1.3 5.815e-229 714.0
XH2_k127_7368689_2 Threonine synthase K01733 - 4.2.3.1 8.124e-220 691.0
XH2_k127_7368689_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 369.0
XH2_k127_7368689_4 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000001948 239.0
XH2_k127_739369_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 338.0
XH2_k127_739369_1 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 345.0
XH2_k127_739369_2 24 kD subunit K00122 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000005681 224.0
XH2_k127_739369_3 - - - - 0.00000000000000000000000005695 116.0
XH2_k127_739369_4 PFAM Outer membrane efflux protein - - - 0.00000000000000001383 94.0
XH2_k127_7399579_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 322.0
XH2_k127_7399579_1 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000005541 195.0
XH2_k127_7399579_2 - - - - 0.000000000000000000000000000002563 134.0
XH2_k127_7414123_0 Peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 541.0
XH2_k127_7414123_1 Peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 399.0
XH2_k127_7414123_2 lipid carrier protein - - - 0.0005209 51.0
XH2_k127_7415478_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 2.572e-254 797.0
XH2_k127_7415478_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000001149 50.0
XH2_k127_7431346_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 351.0
XH2_k127_7431346_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 334.0
XH2_k127_7431346_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 329.0
XH2_k127_7431346_3 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000001369 141.0
XH2_k127_7431346_4 - - - - 0.0000000000000000000001118 103.0
XH2_k127_7460799_0 DNA polymerase K02337 - 2.7.7.7 2.879e-217 684.0
XH2_k127_7474389_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922,K06281 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 399.0
XH2_k127_7474389_1 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 356.0
XH2_k127_7474389_2 PFAM HupH hydrogenase expression protein, C-terminal conserved region K03618 - - 0.0000000000000001689 85.0
XH2_k127_7482_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 454.0
XH2_k127_7482_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 315.0
XH2_k127_7482_2 SAF K00003 - 1.1.1.3 0.00000000000000336 77.0
XH2_k127_7482_3 PFAM cytochrome c, class I K08738 - - 0.000000000003972 76.0
XH2_k127_7482_4 PFAM cytochrome c, class I K08738 - - 0.00000007309 63.0
XH2_k127_7490481_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000005521 180.0
XH2_k127_7506214_0 4Fe-4S double cluster binding domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 335.0
XH2_k127_7506214_1 COG0695 Glutaredoxin and related proteins - - - 0.00000000000000000000000000001321 125.0
XH2_k127_7506214_2 SdpI/YhfL protein family - - - 0.00000000000000000383 96.0
XH2_k127_7506214_3 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03789,K03790,K03896 - 2.3.1.102,2.3.1.128 0.00000001338 64.0
XH2_k127_7515631_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 463.0
XH2_k127_7515631_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 376.0
XH2_k127_7515631_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 357.0
XH2_k127_7515631_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000009326 252.0
XH2_k127_7515631_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000002191 201.0
XH2_k127_7515631_5 Copper resistance protein D - - - 0.000000000000000000000000000000000000000000000000000002063 194.0
XH2_k127_7542142_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 4.602e-252 785.0
XH2_k127_7542142_1 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 486.0
XH2_k127_7542142_2 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000000000000002608 235.0
XH2_k127_7542142_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000001656 126.0
XH2_k127_7542142_4 Saccharopine dehydrogenase - - - 0.000000003315 59.0
XH2_k127_7543730_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1e-321 992.0
XH2_k127_7543730_1 ATP synthase (C/AC39) subunit K02119 - - 0.000000000000000000000000000000465 128.0
XH2_k127_7543730_2 - - - - 0.0000000000000000001575 92.0
XH2_k127_755512_0 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 433.0
XH2_k127_755512_1 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000002208 226.0
XH2_k127_755512_2 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000000000402 165.0
XH2_k127_7567360_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.56e-241 757.0
XH2_k127_7567360_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 406.0
XH2_k127_7567360_2 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 354.0
XH2_k127_7567360_3 4Fe-4S ferredoxin K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 287.0
XH2_k127_7567360_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002137 273.0
XH2_k127_7567360_5 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000002247 252.0
XH2_k127_7567360_6 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000001718 222.0
XH2_k127_7593704_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1019.0
XH2_k127_7593704_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 9.971e-292 938.0
XH2_k127_7593704_2 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 2.765e-217 681.0
XH2_k127_7593704_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 577.0
XH2_k127_7593704_4 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 295.0
XH2_k127_7596048_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.172e-295 918.0
XH2_k127_7596048_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 512.0
XH2_k127_7596048_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 321.0
XH2_k127_7596048_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 315.0
XH2_k127_7596048_4 Rod shape-determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 291.0
XH2_k127_7596048_5 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000005052 163.0
XH2_k127_7596048_6 Biopolymer transport protein K03559 - - 0.00000000002665 64.0
XH2_k127_7605225_0 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002548 244.0
XH2_k127_7605225_1 PFAM transcription elongation factor GreA GreB - - - 0.00000000000000000000000000000000000000000000000003195 188.0
XH2_k127_7605225_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000004408 87.0
XH2_k127_7605225_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000001181 54.0
XH2_k127_772410_0 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
XH2_k127_772410_1 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 412.0
XH2_k127_772410_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000003311 159.0
XH2_k127_772410_3 protein conserved in bacteria K09937 - - 0.0000000000000000849 89.0
XH2_k127_7732328_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 400.0
XH2_k127_7732328_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 288.0
XH2_k127_7732328_2 ApaG domain - - - 0.000000000000000000000000000000000000000000000000001546 205.0
XH2_k127_7732328_3 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.0000004364 58.0
XH2_k127_7761368_0 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 422.0
XH2_k127_7761368_1 - - - - 0.000000000000000000000002283 105.0
XH2_k127_7761368_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000007115 102.0
XH2_k127_7761368_3 - - - - 0.000000000000000000273 95.0
XH2_k127_7775902_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 526.0
XH2_k127_7775902_1 N-acetylmuramoyl-L-alanine amidase (Family 2) K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000001841 212.0
XH2_k127_7791816_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1407.0
XH2_k127_7791816_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 403.0
XH2_k127_7791816_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000002442 200.0
XH2_k127_7791816_3 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03774 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000012 125.0
XH2_k127_7791816_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000002197 76.0
XH2_k127_7792725_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 6.845e-242 755.0
XH2_k127_7792725_1 (GGDEF) domain K21024 - 3.1.4.52 5.123e-207 677.0
XH2_k127_7792725_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000001919 227.0
XH2_k127_7792725_3 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000003505 144.0
XH2_k127_7792725_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000001822 114.0
XH2_k127_7792725_5 protein conserved in bacteria K09806 - - 0.00000000000000000000003104 102.0
XH2_k127_7794818_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.45e-300 930.0
XH2_k127_7794818_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.805e-229 714.0
XH2_k127_7794818_2 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 440.0
XH2_k127_7794818_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 351.0
XH2_k127_7794818_4 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 265.0
XH2_k127_7794818_5 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000009751 171.0
XH2_k127_7794818_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000000008613 130.0
XH2_k127_7794818_7 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000001579 78.0
XH2_k127_7807275_0 RNA polymerase sigma factor K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 430.0
XH2_k127_7807275_1 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000001152 214.0
XH2_k127_7807733_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1166.0
XH2_k127_7807733_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 531.0
XH2_k127_7807733_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 387.0
XH2_k127_7831300_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 466.0
XH2_k127_7831300_1 Resolvase, N terminal domain - - - 0.000003517 51.0
XH2_k127_7850134_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 295.0
XH2_k127_7850134_1 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009878 277.0
XH2_k127_7850134_2 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000519 49.0
XH2_k127_7851077_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.653e-304 945.0
XH2_k127_7859501_0 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 346.0
XH2_k127_7859501_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 332.0
XH2_k127_7859501_2 4-hydroxybenzoyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000000009968 169.0
XH2_k127_7859501_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000005733 59.0
XH2_k127_7861477_0 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000003391 140.0
XH2_k127_7861477_1 - - - - 0.00000000000001215 76.0
XH2_k127_7861477_2 Protein of unknown function (DUF3313) - - - 0.0000006073 56.0
XH2_k127_7864221_0 GAF domain K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 373.0
XH2_k127_7864221_1 Flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009966 253.0
XH2_k127_7864221_2 Belongs to the peptidase S8 family - - - 0.0000000004035 64.0
XH2_k127_7868237_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 435.0
XH2_k127_7868237_1 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 368.0
XH2_k127_7868237_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 288.0
XH2_k127_7868237_3 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000000000000000000000000000000000000000000000000000102 217.0
XH2_k127_7868237_4 Cytochrome c K08738 - - 0.0000000000000000000000000000001841 127.0
XH2_k127_7868237_5 Cytochrome c K08738 - - 0.00000000000000000000000000009509 124.0
XH2_k127_7911068_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001191 259.0
XH2_k127_7911068_1 META domain - - - 0.0000000000000000000000000000000000000000000000000000000000008578 226.0
XH2_k127_791187_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 426.0
XH2_k127_791187_1 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 291.0
XH2_k127_791187_2 Protein of unknown function (DUF3617) - - - 0.000000000000000000005146 98.0
XH2_k127_791187_3 - - - - 0.000000000000001988 81.0
XH2_k127_791187_4 Protein of unknown function (DUF2934) - - - 0.000000001 63.0
XH2_k127_7963333_0 Glycosyltransferase WbsX - - - 1.146e-194 629.0
XH2_k127_7970366_0 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 523.0
XH2_k127_7970366_1 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 336.0
XH2_k127_7975683_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000005802 195.0
XH2_k127_7975683_1 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000000000000000004573 189.0
XH2_k127_7975683_2 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000000002485 153.0
XH2_k127_8035235_0 Sulfate transporter antisigma-factor antagonist STAS - - - 5.24e-298 929.0
XH2_k127_8035235_1 Sulfate permease family K03321 - - 6.124e-233 737.0
XH2_k127_8035235_2 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 349.0
XH2_k127_8035235_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 333.0
XH2_k127_8062861_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1405.0
XH2_k127_8062861_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004293 263.0
XH2_k127_8062861_2 Domain of unknown function (DUF4149) - - - 0.00000000000000000000000000000000000007222 148.0
XH2_k127_8083951_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 518.0
XH2_k127_8083951_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 443.0
XH2_k127_8083951_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 295.0
XH2_k127_8083951_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 299.0
XH2_k127_8083951_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000003845 152.0
XH2_k127_8083951_5 Protein of unknown function (DUF493) K09158 - - 0.000000000000000000000000005407 124.0
XH2_k127_8089767_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008636 286.0
XH2_k127_8089767_1 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000009194 254.0
XH2_k127_8089767_2 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000000000000000007536 212.0
XH2_k127_8089767_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000121 207.0
XH2_k127_8099094_0 Belongs to the GMC oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 632.0
XH2_k127_8099094_1 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 561.0
XH2_k127_8099094_2 - - - - 0.00000000000000000000000000000000000000000000000000000009785 204.0
XH2_k127_8099094_3 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000001081 183.0
XH2_k127_81264_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 531.0
XH2_k127_81264_1 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 424.0
XH2_k127_81264_2 Domain of unknown function (DUF4124) - - - 0.000008409 48.0
XH2_k127_8185139_0 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 453.0
XH2_k127_8185139_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 424.0
XH2_k127_8185139_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 316.0
XH2_k127_8185139_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 312.0
XH2_k127_8185139_4 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000006546 178.0
XH2_k127_8190823_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 456.0
XH2_k127_8190823_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000001448 122.0
XH2_k127_8190823_2 ATP-grasp domain - - - 0.00000004596 56.0
XH2_k127_8191524_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 2.063e-222 698.0
XH2_k127_8191524_1 Thioesterase superfamily K10806 - - 0.000000000000000000000000008291 110.0
XH2_k127_8200529_0 Circularly permuted ATP-grasp type 2 - - - 1.616e-230 723.0
XH2_k127_8200529_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 377.0
XH2_k127_8200529_2 Putative amidoligase enzyme (DUF2126) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 322.0
XH2_k127_8200529_3 PFAM 20S proteasome A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 313.0
XH2_k127_8200529_4 glycosyl transferase family - - - 0.0000000001061 62.0
XH2_k127_8207860_0 Multi-copper K06324,K22350 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 458.0
XH2_k127_8207860_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 346.0
XH2_k127_8209380_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 2.535e-320 992.0
XH2_k127_8209380_1 Dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000007572 173.0
XH2_k127_8209380_2 Pfam Glutaredoxin - - - 0.00000000000000000000000000000000002183 146.0
XH2_k127_8220570_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 396.0
XH2_k127_8220570_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 342.0
XH2_k127_8220570_2 dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000001664 63.0
XH2_k127_8220570_3 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00007901 46.0
XH2_k127_8225534_0 von Willebrand factor (vWF) type A domain - - - 0.0 1201.0
XH2_k127_8225534_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 492.0
XH2_k127_8225534_2 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 488.0
XH2_k127_8225534_3 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000002264 220.0
XH2_k127_8225534_4 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000000000001241 71.0
XH2_k127_8255512_0 AMP-binding enzyme K01897 - 6.2.1.3 9.465e-238 747.0
XH2_k127_8255512_1 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 435.0
XH2_k127_8255512_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003871 261.0
XH2_k127_8255512_3 Bacterial transcriptional activator domain - - - 0.00000000002939 65.0
XH2_k127_8265484_0 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 317.0
XH2_k127_8265484_1 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000002628 151.0
XH2_k127_8265484_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000001991 145.0
XH2_k127_8265484_3 - - - - 0.00000000000000000000000000000003845 127.0
XH2_k127_8280245_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 379.0
XH2_k127_8280245_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000186 195.0
XH2_k127_8280693_0 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 447.0
XH2_k127_8280693_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000000003778 170.0
XH2_k127_8280693_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000004856 130.0
XH2_k127_8280693_3 Ni,Fe-hydrogenase I large subunit - - - 0.000000000000000000007743 94.0
XH2_k127_8311351_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 335.0
XH2_k127_8311351_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 329.0
XH2_k127_8311351_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 0.00000000000000000000000000006888 117.0
XH2_k127_8311351_3 - - - - 0.0006473 47.0
XH2_k127_8341929_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.601e-212 666.0
XH2_k127_8341929_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 370.0
XH2_k127_8341929_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000001833 236.0
XH2_k127_8345939_0 Acyl-CoA dehydrogenase N terminal K20035 - - 1.04e-226 711.0
XH2_k127_8345939_1 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 421.0
XH2_k127_8370941_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 1.938e-250 783.0
XH2_k127_8370941_1 PFAM Aminotransferase, class V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 310.0
XH2_k127_8370941_2 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001698 270.0
XH2_k127_8370941_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000003084 163.0
XH2_k127_8370941_4 - - - - 0.000000000000000000000000000000000001337 148.0
XH2_k127_8370941_5 - - - - 0.000000146 55.0
XH2_k127_8370941_6 - - - - 0.0001815 45.0
XH2_k127_8371552_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 391.0
XH2_k127_8371552_1 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000001026 127.0
XH2_k127_8371552_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000003473 93.0
XH2_k127_8399812_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.394e-221 721.0
XH2_k127_8399812_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 455.0
XH2_k127_8399812_2 Glycosyl transferase family 2 - - - 0.000000000000000000000009413 104.0
XH2_k127_8417447_0 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 596.0
XH2_k127_8417447_1 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 567.0
XH2_k127_8417447_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 562.0
XH2_k127_8417447_3 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000944 436.0
XH2_k127_8440793_0 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 501.0
XH2_k127_8440793_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001452 235.0
XH2_k127_8446255_0 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000001152 211.0
XH2_k127_8446255_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001877 216.0
XH2_k127_8446255_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000205 202.0
XH2_k127_8455656_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.77e-208 649.0
XH2_k127_8455656_1 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000001144 77.0
XH2_k127_8455656_2 Bacterial protein of unknown function (DUF883) - - - 0.000000000003503 66.0
XH2_k127_8464957_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 605.0
XH2_k127_8464957_1 synthetase, class II (G H P K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 507.0
XH2_k127_8464957_2 Transcriptional regulator K15539 - - 0.000000000000000000000000208 108.0
XH2_k127_8469570_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.253e-218 689.0
XH2_k127_8469570_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 306.0
XH2_k127_8469570_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000001461 181.0
XH2_k127_8471498_0 Large family of predicted nucleotide-binding domains K07175 - - 3.617e-232 722.0
XH2_k127_8471498_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 599.0
XH2_k127_8471498_2 CHAT domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 364.0
XH2_k127_8471498_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 295.0
XH2_k127_851082_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 556.0
XH2_k127_851082_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 508.0
XH2_k127_851082_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 395.0
XH2_k127_8512869_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.515e-282 877.0
XH2_k127_8516303_0 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 411.0
XH2_k127_8516303_1 Binding-protein-dependent transport system inner membrane component K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 319.0
XH2_k127_8516303_2 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 299.0
XH2_k127_8516303_3 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000002378 166.0
XH2_k127_8516303_4 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000001503 94.0
XH2_k127_8518233_0 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 406.0
XH2_k127_8518233_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000003022 219.0
XH2_k127_8518233_2 Universal stress protein - - - 0.0000000000000000000000000000000000000007447 153.0
XH2_k127_8518233_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000005567 130.0
XH2_k127_851971_0 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 457.0
XH2_k127_851971_1 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000000000000000000001132 236.0
XH2_k127_851971_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000001491 86.0
XH2_k127_8534876_0 Transport of potassium into the cell K03549 - - 3.434e-273 853.0
XH2_k127_8534876_1 Thioredoxin-like domain - - - 0.00000000000000000002421 93.0
XH2_k127_8534876_2 LytTr DNA-binding domain K08083 - - 0.000007112 48.0
XH2_k127_8534946_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 0.00000000000000000000000000000000000000000000000001338 184.0
XH2_k127_8534946_1 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000000000000000001666 179.0
XH2_k127_8534946_2 chain release factor K15034 - - 0.0000000000000000000000000000000000000000000588 169.0
XH2_k127_8585706_0 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 377.0
XH2_k127_8585706_1 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 391.0
XH2_k127_8585706_2 Transcriptional regulator - - - 0.000000000000000000003485 97.0
XH2_k127_8589254_0 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000743 279.0
XH2_k127_8589254_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000006879 186.0
XH2_k127_8589254_2 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000003 133.0
XH2_k127_868201_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 474.0
XH2_k127_868201_1 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003182 259.0
XH2_k127_868201_2 Glycine zipper 2TM domain - - - 0.00000007876 59.0
XH2_k127_8700010_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1178.0
XH2_k127_8700010_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000001072 124.0
XH2_k127_8701211_0 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000006149 201.0
XH2_k127_8701211_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000001231 194.0
XH2_k127_8701211_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000002904 180.0
XH2_k127_8701211_3 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000001127 166.0
XH2_k127_8701211_4 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000001469 156.0
XH2_k127_8701211_5 psiF repeat - - - 0.000000000000000000000000000000000000003606 151.0
XH2_k127_8701211_6 KTSC domain - - - 0.00000000000000002815 83.0
XH2_k127_8716190_0 Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 597.0
XH2_k127_8716190_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 480.0
XH2_k127_8716190_2 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 327.0
XH2_k127_8716190_3 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000000000000000000000007528 227.0
XH2_k127_8722403_0 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007954 251.0
XH2_k127_8722403_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000002288 204.0
XH2_k127_8722403_2 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000001029 178.0
XH2_k127_8722403_3 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 0.0000000000000000000000000000000000000000002925 171.0
XH2_k127_8727796_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 3.442e-274 852.0
XH2_k127_8727796_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000004672 113.0
XH2_k127_8753134_0 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 591.0
XH2_k127_8795640_0 Glycosyl transferases group 1 K12989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 459.0
XH2_k127_8795640_1 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 352.0
XH2_k127_8795640_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003484 271.0
XH2_k127_8795640_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000007435 216.0
XH2_k127_8824328_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 436.0
XH2_k127_8824328_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 326.0
XH2_k127_8824328_2 electron transfer activity K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.0000000000004708 69.0
XH2_k127_8829345_0 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 562.0
XH2_k127_8829345_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 535.0
XH2_k127_8834461_0 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 437.0
XH2_k127_8834461_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 441.0
XH2_k127_8834461_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 391.0
XH2_k127_8834461_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000006334 257.0
XH2_k127_8954088_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000001399 149.0
XH2_k127_8954088_1 PFAM Glycosyl transferase family 2 K12990 - - 0.0000000000000000000000000001753 121.0
XH2_k127_8954088_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000003781 108.0
XH2_k127_8954088_3 - K21495 - - 0.00000000000000000001208 93.0
XH2_k127_8967677_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 427.0
XH2_k127_8967677_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 406.0
XH2_k127_8967677_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 353.0
XH2_k127_8967677_3 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 355.0
XH2_k127_8967677_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000002468 233.0
XH2_k127_8967677_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000000000000000000000000002881 211.0
XH2_k127_8967677_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000203 202.0
XH2_k127_8967677_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000142 199.0
XH2_k127_8967677_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000009252 138.0
XH2_k127_9012070_0 Response regulator receiver K07714,K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 599.0
XH2_k127_9012070_1 PFAM Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 531.0
XH2_k127_9012070_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000001299 108.0
XH2_k127_9012070_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000001426 81.0
XH2_k127_9012070_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000009607 71.0
XH2_k127_9067018_0 MMPL family - - - 7.682e-305 951.0
XH2_k127_9067018_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 331.0
XH2_k127_9069931_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 598.0
XH2_k127_9069931_1 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 286.0
XH2_k127_9101376_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 541.0
XH2_k127_9101376_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006864 265.0
XH2_k127_913487_0 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 304.0
XH2_k127_913487_1 methyltransferase - - - 0.0000000000000000000001958 98.0
XH2_k127_9144254_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 6.011e-270 843.0
XH2_k127_9144254_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 612.0
XH2_k127_9144254_2 dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 293.0
XH2_k127_9144254_3 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000004807 149.0
XH2_k127_9144254_4 periplasmic protein - - - 0.00000000000000000001424 103.0
XH2_k127_9189994_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1144.0
XH2_k127_9189994_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.034e-294 921.0
XH2_k127_9189994_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 3.126e-228 722.0
XH2_k127_9189994_3 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 385.0
XH2_k127_9189994_4 (FHA) domain - - - 0.000000000000000000000000000000000000000001877 156.0
XH2_k127_9194869_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.6e-322 998.0
XH2_k127_9194869_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 251.0
XH2_k127_9195265_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 6.499e-204 667.0
XH2_k127_9195265_1 cytochrome c biogenesis protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 358.0
XH2_k127_9195265_2 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 362.0
XH2_k127_9195265_3 amine dehydrogenase activity K08282,K08884 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009405,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010565,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031667,GO:0031668,GO:0031669,GO:0032091,GO:0033554,GO:0036211,GO:0042304,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043393,GO:0043412,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051100,GO:0051704,GO:0051716,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000009033 88.0
XH2_k127_9201729_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1571.0
XH2_k127_9201729_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 6.15e-212 668.0
XH2_k127_9201729_10 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000003803 162.0
XH2_k127_9201729_11 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000007137 132.0
XH2_k127_9201729_12 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000858 108.0
XH2_k127_9201729_14 - - - - 0.0000000000007676 80.0
XH2_k127_9201729_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 409.0
XH2_k127_9201729_3 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 402.0
XH2_k127_9201729_4 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 371.0
XH2_k127_9201729_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 366.0
XH2_k127_9201729_6 Esterase, phb depolymerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005395 289.0
XH2_k127_9201729_7 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000000129 193.0
XH2_k127_9201729_8 TIGRFAM Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000001567 188.0
XH2_k127_9201729_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000001835 173.0
XH2_k127_9211013_0 PFAM Alanine dehydrogenase PNT, C-terminal domain K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 347.0
XH2_k127_9211013_1 NAD(P) transhydrogenase beta subunit K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000004201 178.0
XH2_k127_9211013_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000764 99.0
XH2_k127_9211264_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 460.0
XH2_k127_9211264_1 - - - - 0.000000000000000000000000000000000001967 143.0
XH2_k127_9215419_0 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 520.0
XH2_k127_9215419_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 345.0
XH2_k127_9215419_2 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
XH2_k127_9215419_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester - - - 0.000000000000000000000000000000000000000000001634 172.0
XH2_k127_9215419_4 Cupin 2, conserved barrel domain protein - - - 0.0002416 44.0
XH2_k127_9230822_0 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 545.0
XH2_k127_9230822_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000811 247.0
XH2_k127_9230822_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000006408 228.0
XH2_k127_9230822_3 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000002258 138.0
XH2_k127_9230822_4 - - - - 0.000005509 50.0
XH2_k127_92627_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 374.0
XH2_k127_92627_1 FixH K09926 - - 0.0000000000000000000000000000000000004123 157.0
XH2_k127_92627_2 - - - - 0.0000000000005073 72.0
XH2_k127_92627_3 Protein conserved in bacteria - - - 0.000000000003836 68.0
XH2_k127_926787_0 AcrB/AcrD/AcrF family K03296 - - 5.887e-207 653.0
XH2_k127_926787_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007713 271.0
XH2_k127_933269_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 517.0
XH2_k127_933269_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 499.0
XH2_k127_933269_2 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 419.0
XH2_k127_933269_3 Protein conserved in bacteria - - - 0.000000000003158 72.0
XH2_k127_9340092_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 392.0
XH2_k127_9340092_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 345.0
XH2_k127_9340092_2 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000008683 128.0
XH2_k127_9340092_3 PFAM acyl-coA-binding protein, ACBP - - - 0.0000000000000000000000000181 111.0
XH2_k127_9381056_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 7.285e-248 771.0
XH2_k127_9381056_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.973e-217 683.0
XH2_k127_9381056_10 Outer membrane lipoprotein K06077 - - 0.00000000000001139 77.0
XH2_k127_9381056_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 581.0
XH2_k127_9381056_3 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 482.0
XH2_k127_9381056_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 312.0
XH2_k127_9381056_5 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000005049 265.0
XH2_k127_9381056_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000004785 192.0
XH2_k127_9381056_7 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000006256 178.0
XH2_k127_9381056_8 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000007798 177.0
XH2_k127_9381056_9 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000234 106.0
XH2_k127_9387263_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.347e-219 692.0
XH2_k127_9387263_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 538.0
XH2_k127_9387263_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 442.0
XH2_k127_9387263_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 312.0
XH2_k127_9387263_4 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000009575 153.0
XH2_k127_9387263_5 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000159 122.0
XH2_k127_9405935_0 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 296.0
XH2_k127_9405935_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000286 263.0
XH2_k127_9405935_2 Bacterial transferase hexapeptide K13018 - 2.3.1.201 0.000000000000000000000001429 109.0
XH2_k127_9419205_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 578.0
XH2_k127_9419205_1 ATP synthase (C/AC39) subunit K02119 - - 0.0000000000000000000000000000000000000000000000000000001303 200.0
XH2_k127_9419205_2 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000000000000000002628 171.0
XH2_k127_9419205_3 V-type proton ATPase subunit E K02121 - - 0.000000000000000000000000000005742 128.0
XH2_k127_9419205_4 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.000000000000000000000001042 115.0
XH2_k127_9426851_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 5.992e-204 642.0
XH2_k127_9426851_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 306.0
XH2_k127_9426851_2 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000002317 155.0
XH2_k127_9431546_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1435.0
XH2_k127_9431546_1 24 kD subunit K00122 - 1.17.1.9 8.827e-226 704.0
XH2_k127_9431546_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 529.0
XH2_k127_9431546_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000264 286.0
XH2_k127_9431546_4 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000002005 194.0
XH2_k127_9431546_5 - - - - 0.0001259 48.0
XH2_k127_9433066_0 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 378.0
XH2_k127_9433066_1 Glutathione peroxidase K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000002088 240.0
XH2_k127_9433066_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000206 216.0
XH2_k127_9433066_3 Exopolysaccharide synthesis, ExoD - - - 0.00000000000000000000000000001147 121.0
XH2_k127_9433066_4 GDSL-like Lipase/Acylhydrolase - - - 0.00001096 55.0
XH2_k127_9452025_0 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 523.0
XH2_k127_9452025_1 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000000000000000000004432 151.0
XH2_k127_9452025_2 general secretion pathway protein K02456 - - 0.000000000000000000000000000009917 123.0
XH2_k127_9452025_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K12276 - - 0.000000000000000000001488 95.0
XH2_k127_9465236_0 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 310.0
XH2_k127_9465236_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000002159 189.0
XH2_k127_9465236_2 Phasin protein - - - 0.0000000000000000000000000000000000005005 146.0
XH2_k127_9465236_3 Dioxygenase - - - 0.000000000000000000000000000005656 126.0
XH2_k127_9465236_4 - - - - 0.000000000005164 75.0
XH2_k127_9465236_5 Inner membrane protein PRK11099 K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000001027 66.0
XH2_k127_9498824_0 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 408.0
XH2_k127_9498824_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008241 259.0
XH2_k127_9498824_2 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000009454 117.0
XH2_k127_9498824_3 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.0000000000006844 68.0
XH2_k127_9514963_0 P-loop ATPase protein family K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 394.0
XH2_k127_9514963_1 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000552 187.0
XH2_k127_9514963_2 NusG domain II - - - 0.00000000000000000000000000000000000004306 158.0
XH2_k127_9542861_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 354.0
XH2_k127_9542861_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004086 286.0
XH2_k127_955288_0 Belongs to the malate synthase family K01638 - 2.3.3.9 9.051e-277 860.0
XH2_k127_955288_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 295.0
XH2_k127_955288_2 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000522 251.0
XH2_k127_955288_3 - - - - 0.0000000000000000000000000000000000000000000000000005728 192.0
XH2_k127_955288_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000008561 177.0
XH2_k127_955288_5 (ABC) transporter K05685,K09810 - - 0.00000000000000000000000001383 110.0
XH2_k127_955288_6 Cysteine-rich CWC - - - 0.0000009792 61.0
XH2_k127_9568556_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 394.0
XH2_k127_9568556_1 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 335.0
XH2_k127_9568556_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000002141 53.0
XH2_k127_9569135_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1293.0
XH2_k127_9569135_1 Bacterial protein of unknown function (DUF839) K07093 - - 1.063e-228 728.0
XH2_k127_9569135_10 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000007259 226.0
XH2_k127_9569135_11 LAGLIDADG-like domain - - - 0.0000000000000000000000000000000000000000000000000108 184.0
XH2_k127_9569135_12 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00002461 49.0
XH2_k127_9569135_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 3.162e-195 617.0
XH2_k127_9569135_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 577.0
XH2_k127_9569135_4 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 554.0
XH2_k127_9569135_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 495.0
XH2_k127_9569135_6 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 478.0
XH2_k127_9569135_7 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 368.0
XH2_k127_9569135_8 Pseudouridine synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 334.0
XH2_k127_9569135_9 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
XH2_k127_9600428_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001231 289.0
XH2_k127_9600428_1 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000001513 171.0
XH2_k127_9612894_0 Esterase of the alpha-beta hydrolase superfamily - - - 2.884e-237 763.0
XH2_k127_9612894_1 Tetratricopeptide repeat - - - 1.467e-204 647.0
XH2_k127_9612894_2 Bacterial capsule synthesis protein PGA_cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 510.0
XH2_k127_9612894_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001192 217.0
XH2_k127_9612894_4 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000345 170.0
XH2_k127_9612894_5 ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000006655 158.0
XH2_k127_9612894_6 KAP family P-loop domain - - - 0.00000903 57.0
XH2_k127_9616901_0 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 421.0
XH2_k127_9616901_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000002719 258.0
XH2_k127_9616901_2 TIGRFAM phasin family protein - - - 0.0000000000000000000000000000000009294 139.0
XH2_k127_9616901_3 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.0000000000001219 72.0
XH2_k127_9621045_0 - - - - 0.00000000000000000000000000000000292 138.0
XH2_k127_9621045_1 - - - - 0.000000000000000000001396 108.0
XH2_k127_9621045_2 - - - - 0.0008956 50.0
XH2_k127_9642586_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 602.0
XH2_k127_9642586_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 284.0
XH2_k127_9642586_2 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000002961 111.0
XH2_k127_9652477_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 318.0
XH2_k127_9652477_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001066 261.0
XH2_k127_9652477_2 YGGT family - - - 0.000000000000000000000000000000000000000000000000000000000000000002717 230.0
XH2_k127_9655102_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 2.938e-228 713.0
XH2_k127_9655102_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.827e-196 617.0
XH2_k127_9655102_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 464.0
XH2_k127_9655102_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000001255 126.0
XH2_k127_9681008_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1058.0
XH2_k127_9699083_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 361.0
XH2_k127_9699083_1 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000003534 126.0
XH2_k127_9753702_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 565.0
XH2_k127_9753702_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 526.0
XH2_k127_9753702_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 452.0
XH2_k127_9753702_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000002787 166.0
XH2_k127_9753702_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000004796 138.0
XH2_k127_9772446_0 Histidine kinase - - - 6.022e-229 728.0
XH2_k127_9772446_1 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000003323 204.0
XH2_k127_9772446_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000002827 73.0
XH2_k127_9772446_3 - - - - 0.0000000003911 67.0
XH2_k127_9837398_0 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000000000000298 161.0
XH2_k127_9837398_1 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000001305 71.0
XH2_k127_9837398_2 - - - - 0.00000000002262 70.0
XH2_k127_9848262_0 Amidohydrolase family K00200 - 1.2.7.12 2.631e-283 879.0
XH2_k127_9848262_1 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 327.0
XH2_k127_9848262_2 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002971 282.0
XH2_k127_9848262_3 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.000000000000000000139 90.0
XH2_k127_9848530_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 580.0
XH2_k127_9848530_1 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000004628 127.0
XH2_k127_9851840_0 COG1982 Arginine lysine ornithine decarboxylases K01584 - 4.1.1.19 0.0 1364.0
XH2_k127_9851840_1 Protein of unknown function (DUF560) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 354.0
XH2_k127_9851840_2 PFAM FecR protein - - - 0.000004109 53.0
XH2_k127_9915207_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
XH2_k127_9915207_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000001069 235.0
XH2_k127_9946150_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 571.0
XH2_k127_9946150_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 362.0
XH2_k127_9946150_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 348.0
XH2_k127_9946150_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 322.0
XH2_k127_9967329_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 5.08e-213 675.0
XH2_k127_9967329_1 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 432.0
XH2_k127_9967329_2 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 360.0
XH2_k127_9967329_3 Alpha beta K07018 - - 0.0000000000000000000009386 94.0
XH2_k127_9967329_4 Belongs to the methyltransferase superfamily K07444 - - 0.00004098 46.0
XH2_k127_9975244_0 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000004427 213.0
XH2_k127_9975244_1 Belongs to the Fur family K09826 - - 0.0000000000000000000000000000000000000000000000000000001979 198.0
XH2_k127_9975244_2 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000000004382 142.0
XH2_k127_9975244_3 CBS domain - - - 0.00000000000000000000000000000002309 138.0
XH2_k127_9975244_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000006098 122.0
XH2_k127_9975244_5 Type II transport protein GspH K08084 - - 0.000000000000000000000001316 106.0
XH2_k127_9995970_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 470.0
XH2_k127_9995970_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 333.0
XH2_k127_9995970_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000002778 138.0
XH2_k127_9995970_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000008289 123.0