Overview

ID MAG04442
Name XH3_bin.38
Sample SMP0120
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Methanomethylicia
Order Methanomethylicales
Family Methanomethylicaceae
Genus JACTUC01
Species
Assembly information
Completeness (%) 94.69
Contamination (%) 1.12
GC content (%) 58.0
N50 (bp) 10,617
Genome size (bp) 1,194,160

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1266

Gene name Description KEGG GOs EC E-value Score Sequence
XH3_k127_1109045_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.11e-239 757.0
XH3_k127_1109045_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 556.0
XH3_k127_1109045_2 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
XH3_k127_1109045_3 Fumarate reductase succinate dehydrogenase flavoprotein K18209 - 1.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000003701 246.0
XH3_k127_1109045_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000005088 226.0
XH3_k127_1109045_5 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000698 211.0
XH3_k127_1109045_6 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000001278 59.0
XH3_k127_1109045_7 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.0000205 50.0
XH3_k127_1203003_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 1.318e-223 712.0
XH3_k127_1203003_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 489.0
XH3_k127_1203003_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000003215 261.0
XH3_k127_1203003_3 Uncharacterized protein conserved in archaea (DUF2286) - - - 0.0000000000000001112 85.0
XH3_k127_1203003_4 - - - - 0.00000000000000162 88.0
XH3_k127_1203003_5 - - - - 0.00000000000002145 76.0
XH3_k127_1232956_0 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001803 244.0
XH3_k127_1232956_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000001715 125.0
XH3_k127_1232956_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000006431 133.0
XH3_k127_1232956_3 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00004061 51.0
XH3_k127_1293606_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000001333 230.0
XH3_k127_1293606_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000001942 226.0
XH3_k127_1293606_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000003233 203.0
XH3_k127_1293606_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000000000000747 134.0
XH3_k127_1293606_4 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000006049 82.0
XH3_k127_1293606_5 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.0000000001872 66.0
XH3_k127_1317001_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.885e-240 767.0
XH3_k127_1317001_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 411.0
XH3_k127_1317001_2 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001053 252.0
XH3_k127_1317001_3 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000004564 158.0
XH3_k127_1317001_4 Amino acid synthesis - - - 0.000000000000000000000000000000000000001418 151.0
XH3_k127_1317001_5 Rubredoxin - - - 0.00000000000000000007141 89.0
XH3_k127_1341162_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005809 370.0
XH3_k127_1341162_1 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 324.0
XH3_k127_1341162_2 PFAM elongation factor Tu domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003465 235.0
XH3_k127_1341162_3 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0000000000000000000000000000000000000000000000002844 189.0
XH3_k127_1341162_4 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000001153 170.0
XH3_k127_1341162_5 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000008546 109.0
XH3_k127_1345449_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 403.0
XH3_k127_1345449_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000001461 220.0
XH3_k127_1345449_2 Fe-S cluster K04488 - - 0.0000000000000000000000000000000000000000000000000000000001733 205.0
XH3_k127_1345449_3 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000003359 199.0
XH3_k127_1345449_4 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000004045 179.0
XH3_k127_1345449_5 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000000000007738 163.0
XH3_k127_1345449_6 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000004951 91.0
XH3_k127_1345449_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000007971 100.0
XH3_k127_1345449_8 Transcriptional regulator K07332 - - 0.00000000000000001474 93.0
XH3_k127_1356598_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 439.0
XH3_k127_1356598_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 428.0
XH3_k127_1356598_11 membrane K09167 - - 0.00000000000000000004248 98.0
XH3_k127_1356598_15 Domain of unknown function (DUF1874) - - - 0.0000000004533 64.0
XH3_k127_1356598_17 - - - - 0.000009161 49.0
XH3_k127_1356598_19 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0009869 44.0
XH3_k127_1356598_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000003694 229.0
XH3_k127_1356598_3 DNA polymerase LigD polymerase domain K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000001347 181.0
XH3_k127_1356598_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000001724 179.0
XH3_k127_1356598_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000004438 169.0
XH3_k127_1356598_6 PFAM peptidase M50 - - - 0.0000000000000000000000000001722 126.0
XH3_k127_1356598_7 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000005795 113.0
XH3_k127_1356598_8 NUDIX domain - - - 0.0000000000000000000005382 101.0
XH3_k127_1356598_9 Universal stress protein - - - 0.0000000000000000000009769 101.0
XH3_k127_1385653_0 GTPase of unknown function C-terminal K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 482.0
XH3_k127_1385653_1 nUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000004617 160.0
XH3_k127_1385653_2 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products - - - 0.00000000000000000000003571 104.0
XH3_k127_1385653_3 PFAM Creatininase K01470 - 3.5.2.10 0.0000000000000001889 81.0
XH3_k127_1559949_0 DNA primase K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 413.0
XH3_k127_1559949_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 415.0
XH3_k127_1559949_10 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000009096 85.0
XH3_k127_1559949_11 signal transduction protein with CBS domains - - - 0.000000000000000009857 93.0
XH3_k127_1559949_12 metalloendopeptidase activity - - - 0.000000008064 61.0
XH3_k127_1559949_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 392.0
XH3_k127_1559949_3 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 376.0
XH3_k127_1559949_4 DUF1512 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 314.0
XH3_k127_1559949_5 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008744 252.0
XH3_k127_1559949_6 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000002498 224.0
XH3_k127_1559949_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.0000000000000000000000000000000054 133.0
XH3_k127_1559949_8 signal transduction protein with CBS domains - - - 0.00000000000000000000007179 109.0
XH3_k127_1559949_9 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000006689 102.0
XH3_k127_1645002_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 351.0
XH3_k127_1645002_1 PFAM UDP-glucuronosyl UDP-glucosyltransferase - - - 0.00000000000000000000001139 114.0
XH3_k127_1645002_2 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000001528 90.0
XH3_k127_1645002_3 Thermophilic metalloprotease (M29) - - - 0.00000000000000002846 94.0
XH3_k127_1656068_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 495.0
XH3_k127_1656068_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000005247 252.0
XH3_k127_1656068_10 - - - - 0.000005742 55.0
XH3_k127_1656068_2 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000106 172.0
XH3_k127_1656068_3 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000003346 154.0
XH3_k127_1656068_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K08698,K08699 - - 0.00000000000000000000000000000000000004903 154.0
XH3_k127_1656068_5 DJ-1/PfpI family - - - 0.000000000000000000000000000000001945 136.0
XH3_k127_1656068_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000002613 136.0
XH3_k127_1656068_7 - - - - 0.000000000000000000000000000001801 123.0
XH3_k127_1656068_8 Transcriptional regulator, AbrB family - - - 0.0000000000000000000001419 102.0
XH3_k127_1656068_9 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000003219 81.0
XH3_k127_1657351_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1409.0
XH3_k127_1657351_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1137.0
XH3_k127_1657351_10 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001348 94.0
XH3_k127_1657351_11 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000001238 84.0
XH3_k127_1657351_12 amino acid K03294 - - 0.00003428 49.0
XH3_k127_1657351_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 589.0
XH3_k127_1657351_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 414.0
XH3_k127_1657351_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004048 250.0
XH3_k127_1657351_5 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002419 222.0
XH3_k127_1657351_6 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000001751 168.0
XH3_k127_1657351_7 orotidine-5'-phosphate decarboxylase activity K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000007454 169.0
XH3_k127_1657351_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000001801 152.0
XH3_k127_1657351_9 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000001007 160.0
XH3_k127_1705457_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
XH3_k127_1705457_1 PFAM Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005013 284.0
XH3_k127_1705457_3 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000002123 146.0
XH3_k127_1705457_4 - - - - 0.0000000000000000002286 94.0
XH3_k127_1705457_5 - - - - 0.0000007194 59.0
XH3_k127_1743015_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 424.0
XH3_k127_1743015_1 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 411.0
XH3_k127_1743015_10 Membrane protein of 12 TMs K01992,K07087 - - 0.000000000000001899 90.0
XH3_k127_1743015_11 Phospholipid methyltransferase - - - 0.000000000008794 78.0
XH3_k127_1743015_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 312.0
XH3_k127_1743015_3 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 309.0
XH3_k127_1743015_4 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 301.0
XH3_k127_1743015_5 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000933 258.0
XH3_k127_1743015_6 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.000000000000000000000000000000000000000000000000000000000000000002566 240.0
XH3_k127_1743015_7 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000000000000000004397 210.0
XH3_k127_1743015_8 helix_turn_helix ASNC type - - - 0.000000000000000000000000000002161 124.0
XH3_k127_1743015_9 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.000000000000000000000002132 111.0
XH3_k127_1747480_0 ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 470.0
XH3_k127_1747480_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydromethanopterin (H4MPT) serving as the one- carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 397.0
XH3_k127_1747480_11 - - - - 0.000002304 49.0
XH3_k127_1747480_12 zinc-ribbon domain - - - 0.000008454 53.0
XH3_k127_1747480_13 Glutaredoxin-like domain (DUF836) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0006363 46.0
XH3_k127_1747480_2 PFAM beta-lactamase domain protein K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 353.0
XH3_k127_1747480_3 Peptide methionine sulfoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000155 219.0
XH3_k127_1747480_4 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000004689 213.0
XH3_k127_1747480_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000005295 202.0
XH3_k127_1747480_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000005908 199.0
XH3_k127_1747480_7 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000145 165.0
XH3_k127_1747480_8 PFAM PAC2 family K06869 - - 0.0000000000000000000000000000000002168 141.0
XH3_k127_1747480_9 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000005855 120.0
XH3_k127_1775736_0 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 375.0
XH3_k127_1775736_1 Methyltransferase MtaA K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 337.0
XH3_k127_1775736_10 cobalamin synthesis CobW domain protein K02234 - - 0.00004163 55.0
XH3_k127_1775736_2 Elongator protein 3, MiaB family, Radical SAM K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 332.0
XH3_k127_1775736_3 PFAM Methionine synthase, B12-binding module, cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002899 209.0
XH3_k127_1775736_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000007967 114.0
XH3_k127_1775736_5 Thioesterase superfamily K02614 - - 0.0000000000000000000004269 101.0
XH3_k127_1775736_6 PFAM Uncharacterised ArCR, COG2043 - - - 0.000000000000000000009167 95.0
XH3_k127_1775736_7 YHS domain - - - 0.0000000000000000006336 86.0
XH3_k127_1775736_8 PFAM Radical SAM domain protein - - - 0.00000000000000004616 83.0
XH3_k127_1775736_9 - - - - 0.00000000000006988 75.0
XH3_k127_1820027_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 600.0
XH3_k127_1820027_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 580.0
XH3_k127_1820027_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000005608 104.0
XH3_k127_1820027_11 PFAM regulatory protein, ArsR - - - 0.00000000000000000009648 94.0
XH3_k127_1820027_12 PFAM glutaredoxin - - - 0.000000000000000007429 87.0
XH3_k127_1820027_13 TPR repeat-containing protein - - - 0.00000000000000001157 86.0
XH3_k127_1820027_15 redox-active disulfide protein 2 - - - 0.0000000003321 64.0
XH3_k127_1820027_16 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0055114 - 0.000000000433 63.0
XH3_k127_1820027_18 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00006773 51.0
XH3_k127_1820027_2 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 497.0
XH3_k127_1820027_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 413.0
XH3_k127_1820027_4 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 402.0
XH3_k127_1820027_5 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 374.0
XH3_k127_1820027_6 PFAM permease K07089 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 349.0
XH3_k127_1820027_7 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000398 171.0
XH3_k127_1820027_8 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000001448 163.0
XH3_k127_1820027_9 Thiamine biosynthesis protein (ThiI) K06920 - 6.3.4.20 0.000000000000000000000000000000000003094 145.0
XH3_k127_1941367_0 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 597.0
XH3_k127_1941367_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 441.0
XH3_k127_1941367_2 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000006492 109.0
XH3_k127_199730_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 550.0
XH3_k127_199730_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 346.0
XH3_k127_199730_10 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000004015 105.0
XH3_k127_199730_11 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.00000000000000000004659 98.0
XH3_k127_199730_13 Domain of unknown function (DUF296) K06934 - - 0.00000004758 60.0
XH3_k127_199730_2 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002971 276.0
XH3_k127_199730_3 glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000003033 242.0
XH3_k127_199730_4 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000002965 211.0
XH3_k127_199730_5 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000006534 198.0
XH3_k127_199730_6 DNA polymerase beta domain protein region K07073 - - 0.00000000000000000000000000000000000000000000000000009583 196.0
XH3_k127_199730_7 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000002565 186.0
XH3_k127_199730_8 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.0000000000000000000000000000000001003 145.0
XH3_k127_199730_9 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000001201 112.0
XH3_k127_2129356_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 335.0
XH3_k127_2129356_1 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 306.0
XH3_k127_2129356_2 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000001829 232.0
XH3_k127_2129356_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000001602 151.0
XH3_k127_2151491_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 445.0
XH3_k127_2151491_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 341.0
XH3_k127_2151491_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 312.0
XH3_k127_2151491_3 PUCC protein - - - 0.0000000000000000000000000000000000000000000000000000000002106 218.0
XH3_k127_2151491_4 Arsenite-activated ATPase (ArsA) K01551 - 3.6.3.16 0.000000000000000000000000000000000000006242 155.0
XH3_k127_2151491_5 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000004521 109.0
XH3_k127_2151491_6 Putative Phosphatase - - - 0.0000000000000000000001982 105.0
XH3_k127_2151491_7 Uncharacterized conserved protein (DUF2299) - - - 0.00000000000001908 79.0
XH3_k127_2151491_8 Phosphate uptake regulator - - - 0.000186 48.0
XH3_k127_2216614_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 399.0
XH3_k127_2216614_1 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000004166 98.0
XH3_k127_2250461_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 562.0
XH3_k127_2250461_1 IMP dehydrogenase activity - - - 0.000000000008022 70.0
XH3_k127_2250461_2 Glycine cleavage system P-protein K00281,K00282 - 1.4.4.2 0.00007865 48.0
XH3_k127_2252090_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 538.0
XH3_k127_2252090_1 glycosyl transferase group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 261.0
XH3_k127_2304867_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 471.0
XH3_k127_2304867_1 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000001009 204.0
XH3_k127_2304867_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000004243 128.0
XH3_k127_2346040_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 454.0
XH3_k127_2346040_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009053 398.0
XH3_k127_2346040_10 ferric iron binding K02380 - - 0.000729 44.0
XH3_k127_2346040_2 PFAM major facilitator superfamily MFS_1 K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 333.0
XH3_k127_2346040_3 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 308.0
XH3_k127_2346040_4 signal transduction protein with CBS domains K07744 - - 0.00000000000000000000000000000000000000000000000000000000000000002535 234.0
XH3_k127_2346040_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000002564 218.0
XH3_k127_2346040_6 COG1100 GTPase SAR1 and related small G K06883 - - 0.00000000000000000000000000000000000000000000001638 180.0
XH3_k127_2346040_7 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000008752 166.0
XH3_k127_2346040_8 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000003025 154.0
XH3_k127_2371627_0 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 327.0
XH3_k127_2371627_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000006653 196.0
XH3_k127_2371627_2 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.00000000000000000000000000000000000000000007223 182.0
XH3_k127_2371627_3 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000000000000000000001515 156.0
XH3_k127_2371627_4 Transcriptional regulator PadR-like family - - - 0.000000000005528 68.0
XH3_k127_249401_0 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 278.0
XH3_k127_249401_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000009183 232.0
XH3_k127_249401_2 Winged helix DNA-binding domain K09927 - - 0.000000000000000000000000000000000000007225 152.0
XH3_k127_249401_3 Zn-dependent hydrolases of the - - - 0.0000000000000000000000000000000000002216 151.0
XH3_k127_249401_4 - - - - 0.0000000000000000003836 99.0
XH3_k127_249401_5 glucosylceramidase activity - - - 0.000000000000001269 82.0
XH3_k127_249401_6 Phospholipid methyltransferase - - - 0.000000108 61.0
XH3_k127_249401_7 Bacterial PH domain - - - 0.0001331 52.0
XH3_k127_2525882_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 GO:0003674,GO:0005488,GO:0005515,GO:0042802 6.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 440.0
XH3_k127_2525882_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 342.0
XH3_k127_2525882_10 Belongs to the UPF0248 family K09715 - - 0.000004447 55.0
XH3_k127_2525882_2 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 303.0
XH3_k127_2525882_3 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000001609 220.0
XH3_k127_2525882_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000006334 217.0
XH3_k127_2525882_5 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000002358 215.0
XH3_k127_2525882_6 PFAM Translin K07477 - - 0.00000000000000000000000000000000003265 142.0
XH3_k127_2525882_7 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000001981 104.0
XH3_k127_2525882_8 PFAM Aminotransferase - - - 0.0000000000000000006473 88.0
XH3_k127_2525882_9 methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000004419 85.0
XH3_k127_2526949_0 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 295.0
XH3_k127_2526949_1 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000001478 226.0
XH3_k127_2526949_2 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000000000000000000000000000001458 210.0
XH3_k127_2526949_3 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000001663 170.0
XH3_k127_2526949_4 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000003865 159.0
XH3_k127_2526949_5 PFAM Creatininase K01470 - 3.5.2.10 0.00000000000000000000000004482 113.0
XH3_k127_2526949_6 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000003122 78.0
XH3_k127_2556662_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 437.0
XH3_k127_2556662_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002861 268.0
XH3_k127_2556662_2 Permease for cytosine/purines, uracil, thiamine, allantoin K10974 - - 0.0000000000000000001111 102.0
XH3_k127_2562481_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 3.041e-211 683.0
XH3_k127_2562481_1 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 492.0
XH3_k127_2562481_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 329.0
XH3_k127_2562481_3 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 285.0
XH3_k127_2562481_4 SMART Elongator protein 3 MiaB NifB K06935,K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000001276 168.0
XH3_k127_2562481_5 PFAM AMP-dependent synthetase - - - 0.000000000000000000000000000000002727 142.0
XH3_k127_2562481_6 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000001676 102.0
XH3_k127_2562481_7 - - - - 0.00000002616 59.0
XH3_k127_2679957_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 580.0
XH3_k127_2679957_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 307.0
XH3_k127_2679957_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 313.0
XH3_k127_2679957_3 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000002432 115.0
XH3_k127_2679957_4 Transglutaminase-like superfamily - - - 0.0000000000000005226 92.0
XH3_k127_2683779_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 3.066e-309 977.0
XH3_k127_2683779_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.187e-245 788.0
XH3_k127_2683779_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000002455 199.0
XH3_k127_2683779_3 Protein of unknown function (DUF434) - - - 0.000000000000000000000000000000001248 139.0
XH3_k127_2683779_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001326 106.0
XH3_k127_2702732_0 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000008571 138.0
XH3_k127_2702732_1 serine-type endopeptidase activity K00505,K01342,K02035 - 1.14.18.1,3.4.21.62 0.0000000000000000000000000003155 133.0
XH3_k127_2725615_0 PFAM beta-lactamase domain protein K07041 - - 3.9e-225 715.0
XH3_k127_2725615_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 365.0
XH3_k127_2725615_10 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.00000000000000000000000000003634 124.0
XH3_k127_2725615_11 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000003777 115.0
XH3_k127_2725615_12 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000001121 98.0
XH3_k127_2725615_13 Belongs to the UPF0179 family K09730 - - 0.0000000000000000004711 94.0
XH3_k127_2725615_14 HupF/HypC family K04653 - - 0.00000000000000002025 83.0
XH3_k127_2725615_15 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000004339 75.0
XH3_k127_2725615_16 Protein of unknown function DUF72 - - - 0.0000000000002203 77.0
XH3_k127_2725615_2 hydrogenase expression formation protein K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 353.0
XH3_k127_2725615_3 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001433 276.0
XH3_k127_2725615_4 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000298 271.0
XH3_k127_2725615_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000005087 192.0
XH3_k127_2725615_6 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001158 190.0
XH3_k127_2725615_7 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000004005 149.0
XH3_k127_2725615_8 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000000009485 140.0
XH3_k127_2725615_9 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002589 129.0
XH3_k127_2776679_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 469.0
XH3_k127_2776679_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000001287 164.0
XH3_k127_2776679_2 MFS_1 like family - - - 0.000000000000000002799 92.0
XH3_k127_2778984_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 508.0
XH3_k127_2778984_1 ABC-type cobalt transport system ATPase component K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000659 271.0
XH3_k127_2778984_2 ATP-binding protein K16786 - - 0.00000000000000000000000000000000000000000000000000000000000000000009823 238.0
XH3_k127_2778984_3 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000006264 233.0
XH3_k127_2778984_4 ABC-type cobalt transport system, permease K16785 - - 0.000000000000000000000000000000004321 138.0
XH3_k127_2789313_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 1.075e-218 691.0
XH3_k127_2789313_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 361.0
XH3_k127_2816007_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759,K22503 - 6.1.1.12,6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 510.0
XH3_k127_2816007_1 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 512.0
XH3_k127_2816007_10 - - - - 0.0000008948 51.0
XH3_k127_2816007_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 489.0
XH3_k127_2816007_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000009233 207.0
XH3_k127_2816007_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000004473 207.0
XH3_k127_2816007_5 helix_turn_helix, cAMP Regulatory protein - - - 0.0000000000000000000000000000000000000000001632 163.0
XH3_k127_2816007_6 Transcription elongation factor - - - 0.0000000000000000000000000000005043 128.0
XH3_k127_2816007_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000004975 95.0
XH3_k127_2816007_8 MobA-like NTP transferase domain K03752 - 2.7.7.77 0.000000000000004615 84.0
XH3_k127_2816007_9 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000003495 65.0
XH3_k127_283177_0 Protein of unknown function (DUF475) K09799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 410.0
XH3_k127_283177_1 Eco57I restriction-modification methylase K07317 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 308.0
XH3_k127_283177_10 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000001647 56.0
XH3_k127_283177_11 DNA repair - - - 0.000774 51.0
XH3_k127_283177_2 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 256.0
XH3_k127_283177_3 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000002747 239.0
XH3_k127_283177_4 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000001422 128.0
XH3_k127_283177_5 Major Facilitator Superfamily - - - 0.0000000000000000004615 96.0
XH3_k127_283177_7 ABC-2 type transporter K01992 - - 0.00000000000001139 86.0
XH3_k127_283177_8 WD40-like Beta Propeller Repeat - - - 0.0000000001077 69.0
XH3_k127_283177_9 FMN binding K03809 - 1.6.5.2 0.00000005188 61.0
XH3_k127_2855509_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 9.206e-222 702.0
XH3_k127_2855509_1 Hydrogenase K14123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 412.0
XH3_k127_2855509_10 Putative Fe-S cluster K03616 - - 0.0000000000000004323 87.0
XH3_k127_2855509_11 Domain of unknown function (DUF4040) K14113 - - 0.00000000000000209 78.0
XH3_k127_2855509_12 PFAM Energy-converting hydrogenase B, subunit P K14125 - - 0.000000000002002 70.0
XH3_k127_2855509_13 Archaeal vacuolar-type H -ATPase subunit F K02122 - - 0.00000000006788 66.0
XH3_k127_2855509_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000235 69.0
XH3_k127_2855509_15 Multisubunit Na H antiporter K14117 - - 0.000000001722 68.0
XH3_k127_2855509_16 - K14116 - - 0.0002533 49.0
XH3_k127_2855509_17 PFAM Multiple resistance and pH regulation protein F K14111 - - 0.000369 46.0
XH3_k127_2855509_18 monovalent cation:proton antiporter activity K14112 - - 0.0009782 49.0
XH3_k127_2855509_2 Proton-conducting membrane transporter K14115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004487 285.0
XH3_k127_2855509_3 NADH dehydrogenase K14124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001317 271.0
XH3_k127_2855509_4 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14122 - - 0.000000000000000000000000000000000000000000000000000000437 202.0
XH3_k127_2855509_5 4Fe-4S dicluster domain K14121 - - 0.00000000000000000000000000000000000004119 148.0
XH3_k127_2855509_6 4Fe-4S dicluster domain K14120 - - 0.0000000000000000000000000000001923 128.0
XH3_k127_2855509_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14120 - - 0.0000000000000000000000000000008941 130.0
XH3_k127_2855509_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K14114 - - 0.0000000000000000002932 96.0
XH3_k127_2855509_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000004345 85.0
XH3_k127_2884878_0 DEAD DEAH box helicase domain protein K03724 - - 9.008e-239 765.0
XH3_k127_2884878_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 456.0
XH3_k127_2884878_2 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002816 251.0
XH3_k127_2884878_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000499 257.0
XH3_k127_2884878_4 sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000002248 167.0
XH3_k127_2884878_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000004833 137.0
XH3_k127_2887055_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000606 276.0
XH3_k127_2887055_1 - - - - 0.000000000000000000000000000000000000000000000000001252 191.0
XH3_k127_2887055_2 Ser thr protein kinase K07176 - - 0.00000000000000000000000000000000000000002797 163.0
XH3_k127_2887055_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000006773 74.0
XH3_k127_2887055_4 PFAM OsmC-like protein K07397 - - 0.0000000000000126 79.0
XH3_k127_2887055_5 Putative zinc- or iron-chelating domain K06940 - - 0.00000000003254 69.0
XH3_k127_2887055_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000006373 49.0
XH3_k127_2887055_7 Flavodoxin - - - 0.00001168 51.0
XH3_k127_2887055_8 acetyltransferase - - - 0.0006229 51.0
XH3_k127_2887055_9 Putative PD-(D/E)XK phosphodiesterase (DUF2161) - - - 0.0009008 48.0
XH3_k127_3130110_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 332.0
XH3_k127_3130110_1 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000005842 193.0
XH3_k127_3130110_2 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000003236 177.0
XH3_k127_3130110_3 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000002205 106.0
XH3_k127_3130110_4 - - - - 0.000000000000005088 79.0
XH3_k127_3130110_5 - - - - 0.000000195 59.0
XH3_k127_3165976_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.112e-220 694.0
XH3_k127_3165976_1 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 5.085e-218 687.0
XH3_k127_3165976_10 - - - - 0.000000197 64.0
XH3_k127_3165976_2 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 590.0
XH3_k127_3165976_3 III protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 418.0
XH3_k127_3165976_4 FeS assembly protein SUFB K09014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 373.0
XH3_k127_3165976_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000002192 256.0
XH3_k127_3165976_6 CobW/HypB/UreG, nucleotide-binding domain K03189,K04652 - - 0.00000000000000000000000000000000000000000000000000000003167 201.0
XH3_k127_3165976_7 assembly ATPase K09013 - - 0.00000000000000000000000000000000000000000000000000000003543 205.0
XH3_k127_3165976_8 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000001087 192.0
XH3_k127_3165976_9 Biotin-requiring enzyme - - - 0.0000000000000005081 83.0
XH3_k127_3176716_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.772e-245 782.0
XH3_k127_3176716_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 332.0
XH3_k127_3176716_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000004831 128.0
XH3_k127_3176716_11 Protein of unknown function DUF47 K07220 - - 0.000000000000000000001499 105.0
XH3_k127_3176716_12 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000005743 69.0
XH3_k127_3176716_13 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000005845 66.0
XH3_k127_3176716_14 - - - - 0.00000000127 64.0
XH3_k127_3176716_15 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000292 51.0
XH3_k127_3176716_2 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003791 269.0
XH3_k127_3176716_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006133 261.0
XH3_k127_3176716_4 Binds the lower part of the 30S subunit head K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004309 211.0
XH3_k127_3176716_5 Putative RNA methyltransferase K09142 - - 0.0000000000000000000000000000000000000000000000000006877 194.0
XH3_k127_3176716_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000001028 183.0
XH3_k127_3176716_7 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000001374 158.0
XH3_k127_3176716_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000005414 148.0
XH3_k127_3176716_9 - - - - 0.0000000000000000000000000000000003305 139.0
XH3_k127_3236630_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002575 448.0
XH3_k127_3236630_1 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003877 262.0
XH3_k127_3236630_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000000000201 190.0
XH3_k127_3236630_3 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000001464 151.0
XH3_k127_3236630_4 Permeases of the major facilitator superfamily K08153 - - 0.000000000000000001064 99.0
XH3_k127_3236630_5 Protein disulfide isomerase K01829,K09584 - 5.3.4.1 0.00000000567 62.0
XH3_k127_3236630_6 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.00001032 58.0
XH3_k127_3304268_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 465.0
XH3_k127_3304268_1 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 421.0
XH3_k127_3304268_10 AMP binding K03499,K06149 - - 0.00000000011 68.0
XH3_k127_3304268_11 - - - - 0.00000003274 62.0
XH3_k127_3304268_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 334.0
XH3_k127_3304268_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000001689 199.0
XH3_k127_3304268_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000001481 166.0
XH3_k127_3304268_5 PFAM Radical SAM - - - 0.000000000000000000000000000000000003224 150.0
XH3_k127_3304268_6 - - - - 0.0000000000000000000000000000001724 142.0
XH3_k127_3304268_7 Transcriptional regulator K07722 - - 0.000000000000000000000000001112 116.0
XH3_k127_3304268_8 Conserved protein implicated in secretion - - - 0.0000000000000000000000001932 113.0
XH3_k127_3304268_9 Belongs to the ompA family K20276 - - 0.00000000001871 78.0
XH3_k127_337199_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1037.0
XH3_k127_337199_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 368.0
XH3_k127_337199_10 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000008583 81.0
XH3_k127_337199_11 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000001261 79.0
XH3_k127_337199_12 protein conserved in archaea K09723 - - 0.0000979 51.0
XH3_k127_337199_2 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 331.0
XH3_k127_337199_3 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 314.0
XH3_k127_337199_4 Oligosaccharyl transferase, STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000008168 273.0
XH3_k127_337199_5 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003341 222.0
XH3_k127_337199_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000002063 194.0
XH3_k127_337199_7 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000008627 176.0
XH3_k127_337199_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000002452 138.0
XH3_k127_337199_9 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000002024 116.0
XH3_k127_3392193_0 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000000001281 217.0
XH3_k127_3392193_1 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000004661 146.0
XH3_k127_3392193_2 - - - - 0.00000000000000407 85.0
XH3_k127_343936_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 462.0
XH3_k127_343936_1 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 400.0
XH3_k127_343936_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 280.0
XH3_k127_343936_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.00000000000000000000000000000000000000000000000000000001041 200.0
XH3_k127_343936_4 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000006559 198.0
XH3_k127_343936_5 - - - - 0.00000000000000000000000001641 117.0
XH3_k127_343936_6 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000001585 92.0
XH3_k127_343936_7 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000001871 77.0
XH3_k127_343936_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000003562 71.0
XH3_k127_343936_9 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000644 49.0
XH3_k127_3528384_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001125 286.0
XH3_k127_3528384_1 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004008 268.0
XH3_k127_3528384_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002559 263.0
XH3_k127_3528384_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000004872 209.0
XH3_k127_3528384_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.000000000000000000000000000000000000000000000000000000002567 212.0
XH3_k127_3528384_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000001443 93.0
XH3_k127_3528384_6 Large-conductance mechanosensitive channel, MscL K03282 - - 0.000000000000006455 79.0
XH3_k127_3528384_7 - - - - 0.0003014 47.0
XH3_k127_354171_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 430.0
XH3_k127_354171_1 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 316.0
XH3_k127_354171_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 293.0
XH3_k127_354171_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000005294 178.0
XH3_k127_354171_4 HTH-type transcriptional regulatory protein K07728 - - 0.000000000000000000000000000000000008657 143.0
XH3_k127_354171_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000003448 74.0
XH3_k127_354171_6 Signal recognition particle K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005786,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006617,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0022607,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0042886,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0065003,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:1901363,GO:1990904 - 0.00000000002681 72.0
XH3_k127_354171_7 COG1522 Transcriptional regulators - - - 0.0000000009761 65.0
XH3_k127_354171_8 Gar1/Naf1 RNA binding region K07569 - - 0.00000001654 61.0
XH3_k127_354171_9 Belongs to the UPF0216 family K09737 - - 0.000001425 55.0
XH3_k127_3567978_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 485.0
XH3_k127_3567978_1 PFAM Fmu (Sun) domain protein K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000002406 267.0
XH3_k127_3567978_10 PIN domain of ribonuclease K07060 - - 0.0000000000000000000001186 104.0
XH3_k127_3567978_11 Cysteinyl-tRNA synthetase K01883 - 6.1.1.16 0.000000000000000001959 91.0
XH3_k127_3567978_12 DGC domain - - - 0.00000000000000001431 88.0
XH3_k127_3567978_13 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.000001897 57.0
XH3_k127_3567978_14 PFAM 4Fe-4S binding domain K00338 - 1.6.5.3 0.000005947 51.0
XH3_k127_3567978_2 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000002493 224.0
XH3_k127_3567978_3 Methionine synthase B12-binding module cap domain protein K16179 - - 0.0000000000000000000000000000000000000000000000000000002626 201.0
XH3_k127_3567978_4 LUD domain - - - 0.0000000000000000000000000000000000000000000000001603 183.0
XH3_k127_3567978_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000001677 187.0
XH3_k127_3567978_6 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000001649 163.0
XH3_k127_3567978_7 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000001456 167.0
XH3_k127_3567978_8 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000008523 154.0
XH3_k127_3567978_9 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000005315 109.0
XH3_k127_361864_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 398.0
XH3_k127_361864_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 396.0
XH3_k127_361864_2 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 300.0
XH3_k127_361864_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000002461 130.0
XH3_k127_3634013_0 ERCC4 domain K10896 - - 0.000000000000000000000000000000000000000000000146 177.0
XH3_k127_3634013_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000000000000000000000000000000000001497 163.0
XH3_k127_3634013_2 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000008977 111.0
XH3_k127_3634013_3 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000001299 111.0
XH3_k127_3634013_4 Belongs to the UPF0147 family K09721 - - 0.000000000000000000007252 97.0
XH3_k127_3634013_5 Sulfurtransferase TusA - - - 0.000000000002818 69.0
XH3_k127_3634013_6 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000000003076 72.0
XH3_k127_3634013_7 Bifunctional inositol-1 monophosphatase fructose-1,6-bisphosphatase K01092 - 3.1.3.25 0.00000000006023 67.0
XH3_k127_3634013_8 helix_turn_helix ASNC type K03718 - - 0.0000000008368 65.0
XH3_k127_3634013_9 PFAM DsrE family protein K07235 - - 0.0001316 52.0
XH3_k127_383842_0 methylglyoxal synthase K01734 - 4.2.3.3 0.00000000000000000000000000000000000000000000000003165 181.0
XH3_k127_383842_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000002756 164.0
XH3_k127_383842_2 NfeD-like C-terminal, partner-binding - - - 0.00003613 50.0
XH3_k127_3847552_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 4.284e-203 648.0
XH3_k127_3847552_1 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 434.0
XH3_k127_3847552_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000008126 218.0
XH3_k127_3847552_3 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000007833 164.0
XH3_k127_3847552_4 - - - - 0.00000000000000000008436 98.0
XH3_k127_3847552_5 RNA-binding protein contains TRAM domain - - - 0.0000000000000000001408 90.0
XH3_k127_3847552_6 haloacid dehalogenase-like hydrolase - - - 0.00000000000000007507 94.0
XH3_k127_3847552_7 Lrp/AsnC ligand binding domain - - - 0.000000000004423 69.0
XH3_k127_3847552_8 transglutaminase domain protein - - - 0.00000000002327 76.0
XH3_k127_3847552_9 TIGRFAM glycosyltransferase, MGT family - - - 0.00000003227 61.0
XH3_k127_3976057_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 430.0
XH3_k127_3976057_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 407.0
XH3_k127_3976057_10 small multi-drug export - - - 0.00000000000000000000000000001729 123.0
XH3_k127_3976057_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 344.0
XH3_k127_3976057_3 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000007339 236.0
XH3_k127_3976057_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000003862 222.0
XH3_k127_3976057_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000002962 222.0
XH3_k127_3976057_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000003577 203.0
XH3_k127_3976057_7 Reversibly glycosylated polypeptide - - - 0.0000000000000000000000000000000000000000000000000003436 201.0
XH3_k127_3976057_8 methyltransferase activity - - - 0.00000000000000000000000000000000000000002543 162.0
XH3_k127_3976057_9 methanogenesis marker protein 11 - - - 0.0000000000000000000000000000000000007848 158.0
XH3_k127_4072947_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 320.0
XH3_k127_4072947_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000003606 151.0
XH3_k127_4072947_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000607 128.0
XH3_k127_4072947_3 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000000000000000001369 95.0
XH3_k127_4072947_4 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000001784 95.0
XH3_k127_4072947_5 pfam nmd3 K07562 - - 0.0000000000000006909 90.0
XH3_k127_4127843_0 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003602 271.0
XH3_k127_4127843_1 glycosyl transferase group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000006187 166.0
XH3_k127_413827_0 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 403.0
XH3_k127_413827_1 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 310.0
XH3_k127_413827_10 Transcriptional regulator K07722 - - 0.0000000004025 65.0
XH3_k127_413827_11 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000864 64.0
XH3_k127_413827_12 Psort location Cytoplasmic, score - - - 0.0000003706 56.0
XH3_k127_413827_2 PFAM Phosphoribosyltransferase K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 304.0
XH3_k127_413827_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 302.0
XH3_k127_413827_4 SMART Elongator protein 3 MiaB NifB K06935 - - 0.000000000000000000000000000000000000000000000000000000000006682 213.0
XH3_k127_413827_5 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K01101 - 3.1.3.41 0.00000000000000000000000000000000000000000000000000000000002335 214.0
XH3_k127_413827_6 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000001275 214.0
XH3_k127_413827_7 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000001258 187.0
XH3_k127_413827_8 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000001196 166.0
XH3_k127_413827_9 EamA-like transporter family - - - 0.00000000000000121 87.0
XH3_k127_414723_0 SMART Elongator protein 3 MiaB NifB K07739 - 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 484.0
XH3_k127_414723_1 PFAM Type II IV secretion system protein K06865 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 454.0
XH3_k127_414723_10 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000009482 102.0
XH3_k127_414723_11 tRNA (uracil) methyltransferase activity K10770,K15444 GO:0000049,GO:0001300,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006448,GO:0006725,GO:0006807,GO:0007568,GO:0007569,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0008270,GO:0009451,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016300,GO:0016491,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0019222,GO:0030488,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0032502,GO:0034248,GO:0034470,GO:0034641,GO:0034660,GO:0035690,GO:0042221,GO:0042493,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051213,GO:0051246,GO:0051716,GO:0055114,GO:0060255,GO:0065007,GO:0070887,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:2000112 2.1.1.229 0.000000000000000004156 96.0
XH3_k127_414723_12 Belongs to the thioredoxin family K03671,K05838 - - 0.00000000000000006178 85.0
XH3_k127_414723_13 Acetyl xylan esterase (AXE1) - - - 0.0000001602 61.0
XH3_k127_414723_14 Double zinc ribbon - - - 0.0000003344 55.0
XH3_k127_414723_15 - - - - 0.00000116 61.0
XH3_k127_414723_16 - - - - 0.00008035 51.0
XH3_k127_414723_2 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 355.0
XH3_k127_414723_3 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 343.0
XH3_k127_414723_4 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000006909 253.0
XH3_k127_414723_5 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000005863 205.0
XH3_k127_414723_6 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000002186 203.0
XH3_k127_414723_7 SMART zinc finger, RanBP2-type - - - 0.0000000000000000000000000000000000000000000000000003643 198.0
XH3_k127_414723_8 AsnC family K03718 - - 0.000000000000000000000000000000000000000003865 159.0
XH3_k127_414723_9 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000000000000000001254 154.0
XH3_k127_4217528_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 557.0
XH3_k127_4217528_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 329.0
XH3_k127_4217528_10 FAD binding domain of DNA photolyase K01669 - 4.1.99.3 0.00000000000003974 73.0
XH3_k127_4217528_11 Mo-molybdopterin cofactor metabolic process K03753 - - 0.0000103 53.0
XH3_k127_4217528_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649,K02594 - 2.3.3.13,2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 305.0
XH3_k127_4217528_3 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001195 303.0
XH3_k127_4217528_4 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000001235 220.0
XH3_k127_4217528_5 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000227 211.0
XH3_k127_4217528_6 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K14084 - - 0.0000000000000000000000000000000000000000000000000000257 195.0
XH3_k127_4217528_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000001614 127.0
XH3_k127_4217528_8 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000004272 124.0
XH3_k127_4217528_9 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000001335 116.0
XH3_k127_4260935_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 473.0
XH3_k127_4260935_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 402.0
XH3_k127_4260935_2 SMART serine threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase K01090 - 3.1.3.16 0.000000000000000000000000000000000000009122 158.0
XH3_k127_4260935_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000006812 151.0
XH3_k127_4260935_4 GYD domain - - - 0.00000000000000000000000000000006063 127.0
XH3_k127_4260935_5 - - - - 0.000000000000000000000002892 107.0
XH3_k127_4260935_6 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000001287 98.0
XH3_k127_4260935_7 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs - - - 0.0000000000000001306 89.0
XH3_k127_4422453_0 Heat shock 70 kDa protein K04043 - - 6.379e-241 759.0
XH3_k127_4422453_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005978 274.0
XH3_k127_4422453_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000109 120.0
XH3_k127_4586910_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1014.0
XH3_k127_4586910_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 5.807e-214 679.0
XH3_k127_4586910_10 - - - - 0.000000000000000000000000000008939 130.0
XH3_k127_4586910_11 OsmC-like protein - - - 0.00000000000000000000000009793 112.0
XH3_k127_4586910_12 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000001569 106.0
XH3_k127_4586910_13 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000000000003964 93.0
XH3_k127_4586910_14 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000536 81.0
XH3_k127_4586910_15 - - - - 0.00000000000678 77.0
XH3_k127_4586910_16 PEP-utilising enzyme, mobile domain - - - 0.000000000007302 70.0
XH3_k127_4586910_17 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000009945 52.0
XH3_k127_4586910_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 388.0
XH3_k127_4586910_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
XH3_k127_4586910_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000002252 246.0
XH3_k127_4586910_5 N2,N2-dimethylguanosine tRNA methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000002409 225.0
XH3_k127_4586910_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K00390,K14108 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000005286 201.0
XH3_k127_4586910_7 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000002098 186.0
XH3_k127_4586910_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000001999 156.0
XH3_k127_4586910_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000000226 141.0
XH3_k127_4596411_0 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.00000000000000000000000009969 115.0
XH3_k127_4596411_1 Thioredoxin K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000002911 56.0
XH3_k127_4596411_2 Major facilitator Superfamily - - - 0.00007694 53.0
XH3_k127_461428_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 351.0
XH3_k127_461428_1 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001746 271.0
XH3_k127_461428_2 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
XH3_k127_461428_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000001364 233.0
XH3_k127_461428_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000002556 184.0
XH3_k127_461428_5 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.0000000000000000000000000000000000001172 148.0
XH3_k127_461428_6 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000005233 115.0
XH3_k127_461428_7 Molybdopterin guanine dinucleotide synthesis protein B K03753 - - 0.00000000000000003792 87.0
XH3_k127_461428_8 regulatory protein, arsR - - - 0.000000000001576 77.0
XH3_k127_461428_9 THUMP K06963 - - 0.00000007123 61.0
XH3_k127_4689068_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 376.0
XH3_k127_4689068_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 325.0
XH3_k127_4689068_2 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000001846 135.0
XH3_k127_4689068_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000002415 105.0
XH3_k127_4689068_4 Protein of unknown function (DUF3795) - - - 0.000000002554 60.0
XH3_k127_4723533_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 426.0
XH3_k127_4723533_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 385.0
XH3_k127_4723533_2 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.0000000000000000000000000000000000000000000000000000006666 196.0
XH3_k127_4723533_3 PFAM multiple antibiotic resistance (MarC)-related K05595 - - 0.000000000000000000000000000000000000000003904 163.0
XH3_k127_4723533_4 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000000001939 137.0
XH3_k127_4723533_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000005388 108.0
XH3_k127_4723533_6 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000005209 107.0
XH3_k127_4723533_7 NMT1-like family - - - 0.000000000000000001022 98.0
XH3_k127_4723533_8 HTH DNA binding domain - - - 0.000000008114 61.0
XH3_k127_4745226_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 523.0
XH3_k127_4745226_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 284.0
XH3_k127_4795640_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.706e-296 922.0
XH3_k127_4795640_1 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 429.0
XH3_k127_4795640_2 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 362.0
XH3_k127_4795640_3 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000002968 235.0
XH3_k127_4795640_4 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000006326 100.0
XH3_k127_4795640_5 Starch synthase catalytic domain - - - 0.00000000000001519 81.0
XH3_k127_4815135_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 403.0
XH3_k127_4815135_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 377.0
XH3_k127_4815135_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 298.0
XH3_k127_4815135_3 AAA domain, putative AbiEii toxin, Type IV TA system K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000001535 273.0
XH3_k127_4815135_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000007073 206.0
XH3_k127_4815135_5 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000004434 212.0
XH3_k127_4815135_6 - - - - 0.000000000000000000000000000000000004179 143.0
XH3_k127_4815135_7 - - - - 0.00000000000000000000000000000911 126.0
XH3_k127_4815135_8 Universal stress protein - - - 0.000000004898 63.0
XH3_k127_4844876_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 8.361e-306 951.0
XH3_k127_4844876_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 546.0
XH3_k127_4844876_10 Peptidase S24-like K13280 - 3.4.21.89 0.000004273 57.0
XH3_k127_4844876_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 529.0
XH3_k127_4844876_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 467.0
XH3_k127_4844876_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 323.0
XH3_k127_4844876_5 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006041 247.0
XH3_k127_4844876_6 Indolepyruvate ferredoxin oxidoreductase subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000004165 161.0
XH3_k127_4844876_7 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.0000000000000000000000000000002158 126.0
XH3_k127_4844876_8 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000001355 96.0
XH3_k127_4844876_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000004077 89.0
XH3_k127_4864425_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 339.0
XH3_k127_4864425_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 307.0
XH3_k127_4864425_2 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 313.0
XH3_k127_4864425_3 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000003105 192.0
XH3_k127_4864425_4 PFAM metal-dependent phosphohydrolase, HD sub domain K17487 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.1.4.56 0.0000000000000000000000000000000000000000000667 168.0
XH3_k127_4864425_5 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000022 140.0
XH3_k127_4864425_6 Phosphate uptake regulator - - - 0.000000000000000000000000000002899 129.0
XH3_k127_4864425_7 - K00960 - 2.7.7.6 0.00000000000004329 74.0
XH3_k127_4864425_8 acetyltransferase - - - 0.000000002164 67.0
XH3_k127_4896425_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 326.0
XH3_k127_4896425_1 - - - - 0.0003798 44.0
XH3_k127_4917484_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 448.0
XH3_k127_4917484_1 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 366.0
XH3_k127_4917484_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000001024 206.0
XH3_k127_4917484_3 Belongs to the UPF0434 family - - - 0.000006976 50.0
XH3_k127_4954695_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 6.793e-253 790.0
XH3_k127_4954695_1 PFAM ABC transporter related K00400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 565.0
XH3_k127_4954695_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000005135 161.0
XH3_k127_4954695_11 Transcriptional regulator K22206 - - 0.00000000000000000000000000000000000002453 156.0
XH3_k127_4954695_12 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000008315 132.0
XH3_k127_4954695_13 Protein of unknown function (DUF483) - - - 0.00000000000000000000000000000006204 134.0
XH3_k127_4954695_14 transcriptional regulator, XRE family - - - 0.0000000000000000000000327 106.0
XH3_k127_4954695_15 PFAM Haloacid dehalogenase-like hydrolase K17686 - 3.6.3.54 0.00000000000000001312 93.0
XH3_k127_4954695_16 - K02339 - 2.7.7.7 0.000000000009348 72.0
XH3_k127_4954695_17 Transcriptional regulator K07108,K22206 - - 0.00000004452 61.0
XH3_k127_4954695_18 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.0000002242 56.0
XH3_k127_4954695_2 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 527.0
XH3_k127_4954695_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 505.0
XH3_k127_4954695_4 Phosphomethylpyrimidine kinase K00941,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
XH3_k127_4954695_5 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 394.0
XH3_k127_4954695_6 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 323.0
XH3_k127_4954695_7 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 308.0
XH3_k127_4954695_8 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000003002 211.0
XH3_k127_4954695_9 PFAM TfuA domain protein, core - - - 0.0000000000000000000000000000000000000000000000000003058 192.0
XH3_k127_5074022_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 451.0
XH3_k127_5074022_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 386.0
XH3_k127_5074022_10 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000004166 56.0
XH3_k127_5074022_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 362.0
XH3_k127_5074022_3 Pantothenate synthetase K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 292.0
XH3_k127_5074022_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 264.0
XH3_k127_5074022_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000001243 181.0
XH3_k127_5074022_6 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000002051 162.0
XH3_k127_5074022_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000722 160.0
XH3_k127_5074022_8 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000111 129.0
XH3_k127_5074022_9 DNA topoisomerase, type IA, central domain protein K03168,K03169 - 5.99.1.2 0.00000000000003169 75.0
XH3_k127_5093964_0 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 343.0
XH3_k127_5093964_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000001315 200.0
XH3_k127_5136430_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 317.0
XH3_k127_5136430_1 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000000000004984 181.0
XH3_k127_5136430_2 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000001686 152.0
XH3_k127_5136430_3 - - - - 0.00000000000000000000004003 106.0
XH3_k127_5136430_4 - - - - 0.000000001322 63.0
XH3_k127_5183199_0 Homocitrate synthase K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 481.0
XH3_k127_5183199_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
XH3_k127_5183199_2 PFAM phosphoribosyltransferase K07101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008923 246.0
XH3_k127_5183199_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000001922 222.0
XH3_k127_5183199_4 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000002009 217.0
XH3_k127_5183199_5 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000002206 193.0
XH3_k127_5183199_6 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000000000002217 173.0
XH3_k127_5183199_7 Cupin domain - - - 0.000000000000000000000000000000000006298 140.0
XH3_k127_5260709_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 379.0
XH3_k127_5260709_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 306.0
XH3_k127_5260709_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000002491 176.0
XH3_k127_526401_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 332.0
XH3_k127_526401_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 314.0
XH3_k127_526401_10 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002268 68.0
XH3_k127_526401_11 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000002552 71.0
XH3_k127_526401_12 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00002192 53.0
XH3_k127_526401_13 PFAM Ribosomal L18ae LX protein domain K02944 - - 0.00003284 48.0
XH3_k127_526401_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0004845 45.0
XH3_k127_526401_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000005845 199.0
XH3_k127_526401_3 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000468 197.0
XH3_k127_526401_4 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000000000000000006398 182.0
XH3_k127_526401_5 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000001715 169.0
XH3_k127_526401_6 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000001642 154.0
XH3_k127_526401_7 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000001741 138.0
XH3_k127_526401_8 Belongs to the PDCD5 family K06875 - - 0.0000000000000000000000005367 107.0
XH3_k127_526401_9 PFAM metallophosphoesterase - - - 0.0000000000000001579 82.0
XH3_k127_5289023_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01751,K01754 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.3.1.15,4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 456.0
XH3_k127_5289023_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002921 276.0
XH3_k127_5289023_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000002114 156.0
XH3_k127_5289023_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000002242 137.0
XH3_k127_5289023_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000002883 107.0
XH3_k127_5289023_5 Winged helix-turn-helix - - - 0.0000000000002003 73.0
XH3_k127_5330355_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000001914 190.0
XH3_k127_5330355_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000007954 188.0
XH3_k127_5330355_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000003094 108.0
XH3_k127_5348447_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.973e-280 882.0
XH3_k127_5348447_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 585.0
XH3_k127_5348447_10 membrane - - - 0.000000000000000000000000000003027 128.0
XH3_k127_5348447_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000002817 110.0
XH3_k127_5348447_12 PFAM GH3 auxin-responsive promoter - - - 0.000000000000000000006959 105.0
XH3_k127_5348447_13 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000001709 85.0
XH3_k127_5348447_14 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.000000000008962 70.0
XH3_k127_5348447_15 Hemerythrin HHE cation binding domain - - - 0.0000000023 65.0
XH3_k127_5348447_16 ATP synthase (C/AC39) subunit K02119 - - 0.000000008733 66.0
XH3_k127_5348447_17 Lipoate-protein ligase a K03800 - 6.3.1.20 0.00009892 51.0
XH3_k127_5348447_18 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0002703 51.0
XH3_k127_5348447_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002554 275.0
XH3_k127_5348447_3 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000004697 234.0
XH3_k127_5348447_4 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000001555 217.0
XH3_k127_5348447_5 radical SAM domain protein K09711 - - 0.0000000000000000000000000000000000000000000000149 181.0
XH3_k127_5348447_6 ATP hydrolysis coupled proton transport K02123 - - 0.00000000000000000000000000000000000000000004529 182.0
XH3_k127_5348447_7 Radical SAM domain protein K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000735 167.0
XH3_k127_5348447_8 TIGRFAM Glutaredoxin-like domain protein - - - 0.00000000000000000000000000000000000151 146.0
XH3_k127_5348447_9 - - - - 0.0000000000000000000000000000000001647 139.0
XH3_k127_5562927_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 550.0
XH3_k127_5562927_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000008775 205.0
XH3_k127_5562927_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000001602 188.0
XH3_k127_5629497_0 HELICc2 K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 428.0
XH3_k127_5629497_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 382.0
XH3_k127_5629497_2 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 371.0
XH3_k127_5629497_3 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009005 273.0
XH3_k127_5629497_4 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000439 154.0
XH3_k127_5629497_5 PFAM thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000001842 126.0
XH3_k127_5629497_6 - - - - 0.000001753 57.0
XH3_k127_5679127_0 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 453.0
XH3_k127_5679127_1 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 376.0
XH3_k127_5679127_2 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 360.0
XH3_k127_5679127_3 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001379 263.0
XH3_k127_5679127_4 CoB--CoM heterodisulfide reductase subunit B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008169 259.0
XH3_k127_5679127_5 NADH ubiquinone oxidoreductase, 20 K00331,K14088 - 1.6.5.3 0.00000000000000000000000000000000000000000000006199 173.0
XH3_k127_5679127_6 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000006289 164.0
XH3_k127_5679127_7 4Fe-4S binding domain K12143 - - 0.00000000000000000000002932 107.0
XH3_k127_5679127_8 heterodisulfide reductase K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0001356 48.0
XH3_k127_577230_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 306.0
XH3_k127_577230_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005402 266.0
XH3_k127_577230_10 PFAM Transcription elongation factor Elf1 like - - - 0.000000000000004601 78.0
XH3_k127_577230_11 regulation of nucleic acid-templated transcription - - - 0.00000000000002494 83.0
XH3_k127_577230_13 - - - - 0.0000000003455 64.0
XH3_k127_577230_14 - - - - 0.00000004452 56.0
XH3_k127_577230_17 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000006833 60.0
XH3_k127_577230_18 ORF located using Blastx - - - 0.00000117 57.0
XH3_k127_577230_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000002953 255.0
XH3_k127_577230_3 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000578 250.0
XH3_k127_577230_4 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000001163 156.0
XH3_k127_577230_5 response regulator, receiver K07669 - - 0.00000000000000000000000000000002096 132.0
XH3_k127_577230_6 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000000000000000000000002434 118.0
XH3_k127_577230_7 PFAM phosphatidate cytidylyltransferase - - - 0.0000000000000000000007461 102.0
XH3_k127_577230_8 - - - - 0.000000000000000000007243 93.0
XH3_k127_577230_9 COG1522 Transcriptional regulators - - - 0.0000000000000000002417 89.0
XH3_k127_5781401_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 583.0
XH3_k127_5781401_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 460.0
XH3_k127_5781401_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000001027 94.0
XH3_k127_5781401_11 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000007397 77.0
XH3_k127_5781401_12 Methyltransferase type 11 - - - 0.0000000000002271 77.0
XH3_k127_5781401_13 TIGRFAM MoaD family protein K03636 - - 0.0000000000007256 72.0
XH3_k127_5781401_14 - - - - 0.0000005482 58.0
XH3_k127_5781401_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 343.0
XH3_k127_5781401_3 DUF460 domain containing protein K09150 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006793 279.0
XH3_k127_5781401_4 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001622 242.0
XH3_k127_5781401_5 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000013 218.0
XH3_k127_5781401_6 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000004424 184.0
XH3_k127_5781401_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000003122 180.0
XH3_k127_5781401_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000004209 133.0
XH3_k127_5781401_9 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000004854 135.0
XH3_k127_5811003_0 methylthiotransferase activity K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 320.0
XH3_k127_5811003_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000003991 185.0
XH3_k127_5811003_2 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000001797 129.0
XH3_k127_5811003_3 Pfam:DUF59 - - - 0.00000000000000001965 85.0
XH3_k127_5811003_4 ThiS family K03636 - - 0.000003005 54.0
XH3_k127_5848963_0 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 4.937e-199 642.0
XH3_k127_5848963_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 606.0
XH3_k127_5848963_2 Quinolinate phosphoribosyl transferase, N-terminal domain K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 437.0
XH3_k127_5848963_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 427.0
XH3_k127_5848963_4 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000000000001443 134.0
XH3_k127_5848963_5 GINS complex protein K09723 - - 0.0000000003651 68.0
XH3_k127_5866204_0 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 318.0
XH3_k127_5866204_1 dihydroorotase K01465 - 3.5.2.3 0.00000000000000000002752 92.0
XH3_k127_590364_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 512.0
XH3_k127_590364_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 341.0
XH3_k127_590364_2 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001146 255.0
XH3_k127_590364_3 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000001295 168.0
XH3_k127_592616_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 355.0
XH3_k127_592616_1 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000185 119.0
XH3_k127_592616_2 Glycosyltransferase like family 2 - - - 0.00000000000000000005493 93.0
XH3_k127_592616_3 Glycosyl transferase family 2 - - - 0.00000000001104 68.0
XH3_k127_5991157_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 528.0
XH3_k127_6073199_0 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000000004829 237.0
XH3_k127_6073199_1 Glycosyl transferase family 1 - - - 0.000000000000000000000000003398 120.0
XH3_k127_6073199_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000001428 114.0
XH3_k127_6073199_3 SMART Cystathionine beta-synthase, core - - - 0.0000000005274 63.0
XH3_k127_621928_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 289.0
XH3_k127_621928_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000003326 224.0
XH3_k127_621928_2 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 0.00000000000000000000000000000000000000000000000000002446 200.0
XH3_k127_621928_3 Major Facilitator Superfamily - - - 0.00000000000000000000000002629 123.0
XH3_k127_6304024_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000002551 164.0
XH3_k127_6304024_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000902 158.0
XH3_k127_6304024_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000006452 112.0
XH3_k127_6304024_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000004753 60.0
XH3_k127_6351066_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 454.0
XH3_k127_6351066_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 378.0
XH3_k127_6351066_2 Serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000008245 230.0
XH3_k127_6351066_3 Pfam:KH_3 K06961 - - 0.000000000000000000000000000000000000000000000000231 184.0
XH3_k127_6351066_4 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.000000000000000000000000000000000000000000000005394 192.0
XH3_k127_6351066_5 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000004349 162.0
XH3_k127_6351066_6 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000005094 115.0
XH3_k127_6367356_0 Uncharacterised nucleotidyltransferase - - - 0.000003063 59.0
XH3_k127_6432957_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003097 282.0
XH3_k127_6432957_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000002875 190.0
XH3_k127_6432957_2 PFAM UspA domain protein - - - 0.0000000000000106 79.0
XH3_k127_6501256_0 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000004495 254.0
XH3_k127_6501256_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000002629 242.0
XH3_k127_6501256_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000004215 229.0
XH3_k127_6501256_3 PFAM BioY protein K03523 - - 0.00000000000000000000000000003355 123.0
XH3_k127_6501256_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000001568 109.0
XH3_k127_6501256_5 Conserved protein implicated in secretion - - - 0.0000000000000001329 87.0
XH3_k127_6501256_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000006837 76.0
XH3_k127_6501256_7 Arsenical pump-driving ATPase K01551 - 3.6.3.16 0.0000004386 55.0
XH3_k127_6501256_8 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0008163 48.0
XH3_k127_6547866_0 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000001548 186.0
XH3_k127_6547866_1 epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000003237 167.0
XH3_k127_6791401_0 Trehalose-phosphatase K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000001862 175.0
XH3_k127_6791401_1 Glycosyltransferase - - - 0.000000000000000000000000000000000000000001145 163.0
XH3_k127_6791401_2 PFAM zinc iron permease K07238 - - 0.0000000000000000000000000000000000000001573 159.0
XH3_k127_6791401_3 RNA-binding protein contains TRAM domain - - - 0.000000000000000003367 87.0
XH3_k127_6791401_4 Transporter, small conductance mechanosensitive ion channel MscS family protein K03442 - - 0.0000111 56.0
XH3_k127_6862011_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 379.0
XH3_k127_6862011_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 366.0
XH3_k127_6862011_10 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000004639 193.0
XH3_k127_6862011_11 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000000000000000000000000000000000000000001107 181.0
XH3_k127_6862011_12 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000002618 158.0
XH3_k127_6862011_13 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000001261 156.0
XH3_k127_6862011_14 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000009505 154.0
XH3_k127_6862011_15 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000000001369 142.0
XH3_k127_6862011_16 Belongs to the UPF0201 family K09736 - - 0.000000000000000000000007394 106.0
XH3_k127_6862011_17 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000548 98.0
XH3_k127_6862011_18 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000005166 83.0
XH3_k127_6862011_19 archaeal coiled-coil protein - - - 0.000000000000008989 85.0
XH3_k127_6862011_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K00806,K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 289.0
XH3_k127_6862011_20 - - - - 0.0000000000000256 74.0
XH3_k127_6862011_3 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000004126 256.0
XH3_k127_6862011_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000002709 242.0
XH3_k127_6862011_5 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000003718 239.0
XH3_k127_6862011_6 ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000003698 216.0
XH3_k127_6862011_7 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000017 219.0
XH3_k127_6862011_8 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000001365 198.0
XH3_k127_6862011_9 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000009378 199.0
XH3_k127_6996593_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 527.0
XH3_k127_6996593_1 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 523.0
XH3_k127_6996593_2 PFAM peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 334.0
XH3_k127_6996593_3 Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003751 276.0
XH3_k127_6996593_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000007851 237.0
XH3_k127_6996593_5 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000001157 191.0
XH3_k127_6996593_6 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000002349 160.0
XH3_k127_6996593_7 - - - - 0.00000000000000000001054 101.0
XH3_k127_6996593_8 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.000001907 53.0
XH3_k127_7011391_0 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000002037 119.0
XH3_k127_7011391_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000007126 112.0
XH3_k127_7011391_2 helicase superfamily c-terminal domain - - - 0.000000000000004499 87.0
XH3_k127_7061974_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 2.327e-218 690.0
XH3_k127_7061974_1 in RNase L inhibitor, RLI K06174 - - 7.644e-205 656.0
XH3_k127_7061974_10 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000006894 117.0
XH3_k127_7061974_11 PFAM Transcription factor CBF NF-Y - - - 0.0000000000000004671 80.0
XH3_k127_7061974_12 SMART DNA-directed RNA polymerase, M 15 kDa subunit K03057 - - 0.00000000000005313 75.0
XH3_k127_7061974_13 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000005337 72.0
XH3_k127_7061974_14 TIGRFAM MoaD family protein K03636 - - 0.00000000148 63.0
XH3_k127_7061974_15 KEOPS complex Cgi121-like subunit K09119 - - 0.00000003059 62.0
XH3_k127_7061974_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 410.0
XH3_k127_7061974_3 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001759 262.0
XH3_k127_7061974_4 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000191 173.0
XH3_k127_7061974_5 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.0000000000000000000000000000000000000000000002494 176.0
XH3_k127_7061974_6 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000256 160.0
XH3_k127_7061974_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000003371 149.0
XH3_k127_7061974_8 PFAM ParB domain protein nuclease - - - 0.0000000000000000000000000000000008317 141.0
XH3_k127_7061974_9 THUMP domain K06963 - - 0.000000000000000000000000000001772 126.0
XH3_k127_713787_0 PFAM pyruvate carboxyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 594.0
XH3_k127_713787_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 589.0
XH3_k127_713787_10 COG0608 Single-stranded DNA-specific exonuclease K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 338.0
XH3_k127_713787_11 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 332.0
XH3_k127_713787_12 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 327.0
XH3_k127_713787_13 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 320.0
XH3_k127_713787_14 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 286.0
XH3_k127_713787_15 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001463 280.0
XH3_k127_713787_16 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001574 278.0
XH3_k127_713787_17 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002229 281.0
XH3_k127_713787_18 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003078 271.0
XH3_k127_713787_19 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002179 271.0
XH3_k127_713787_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 550.0
XH3_k127_713787_20 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
XH3_k127_713787_21 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000004433 263.0
XH3_k127_713787_22 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000006709 262.0
XH3_k127_713787_23 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000001714 228.0
XH3_k127_713787_24 PFAM ABC transporter related K03529,K06166,K16786,K16787 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000000004221 227.0
XH3_k127_713787_25 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000009161 228.0
XH3_k127_713787_26 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000001039 228.0
XH3_k127_713787_27 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000003917 216.0
XH3_k127_713787_28 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
XH3_k127_713787_29 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000001861 212.0
XH3_k127_713787_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 531.0
XH3_k127_713787_30 RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000002264 209.0
XH3_k127_713787_31 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000006255 206.0
XH3_k127_713787_32 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002384 199.0
XH3_k127_713787_33 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000001501 192.0
XH3_k127_713787_34 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000003723 192.0
XH3_k127_713787_35 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000004321 186.0
XH3_k127_713787_36 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000006281 184.0
XH3_k127_713787_37 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000009246 185.0
XH3_k127_713787_38 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000166 182.0
XH3_k127_713787_39 RIO1 family K08851 - 2.7.11.1 0.000000000000000000000000000000000000000000000004914 179.0
XH3_k127_713787_4 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 516.0
XH3_k127_713787_40 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000001991 173.0
XH3_k127_713787_41 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000002443 167.0
XH3_k127_713787_42 Methyltransferase small domain K00564 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.172 0.00000000000000000000000000000000000000000002449 168.0
XH3_k127_713787_43 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000003132 164.0
XH3_k127_713787_44 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000006003 162.0
XH3_k127_713787_45 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000008049 156.0
XH3_k127_713787_46 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000002574 154.0
XH3_k127_713787_47 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000007043 149.0
XH3_k127_713787_48 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000001161 144.0
XH3_k127_713787_49 Binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000001291 139.0
XH3_k127_713787_5 GTPase of K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 440.0
XH3_k127_713787_50 Binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002427 139.0
XH3_k127_713787_51 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000008774 138.0
XH3_k127_713787_52 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000837 132.0
XH3_k127_713787_53 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000007655 137.0
XH3_k127_713787_54 pyridine nucleotide-disulfide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000009144 132.0
XH3_k127_713787_55 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002894 124.0
XH3_k127_713787_56 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000003375 117.0
XH3_k127_713787_57 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000002008 121.0
XH3_k127_713787_58 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000371 111.0
XH3_k127_713787_59 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000000004411 105.0
XH3_k127_713787_6 Sodium:neurotransmitter symporter family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 440.0
XH3_k127_713787_60 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000006447 105.0
XH3_k127_713787_61 binds to the 23S rRNA K02921 - - 0.0000000000000000000002003 99.0
XH3_k127_713787_62 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000002207 96.0
XH3_k127_713787_63 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.00000000000000000004561 100.0
XH3_k127_713787_64 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000682 94.0
XH3_k127_713787_65 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.000000000000000001918 85.0
XH3_k127_713787_66 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000004507 85.0
XH3_k127_713787_67 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000005006 78.0
XH3_k127_713787_68 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000002302 76.0
XH3_k127_713787_69 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000005211 74.0
XH3_k127_713787_7 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009555 407.0
XH3_k127_713787_70 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.00000000000008035 75.0
XH3_k127_713787_71 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000003732 73.0
XH3_k127_713787_72 membrane - - - 0.00000000005773 70.0
XH3_k127_713787_73 RNA binding K07581 - - 0.00000000005943 69.0
XH3_k127_713787_74 Probably involved in the biogenesis of the ribosome K14561 - - 0.0000000003052 68.0
XH3_k127_713787_75 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.000000006512 61.0
XH3_k127_713787_76 Transcription factor Pcc1 K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.0001315 52.0
XH3_k127_713787_77 Nucleotide binding protein, PINc K07158 GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0004237 48.0
XH3_k127_713787_78 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.0008178 50.0
XH3_k127_713787_79 - - - - 0.0008789 47.0
XH3_k127_713787_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 387.0
XH3_k127_713787_9 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 382.0
XH3_k127_7239843_0 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000003908 223.0
XH3_k127_7239843_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000005674 182.0
XH3_k127_7239843_2 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000802 145.0
XH3_k127_7239843_3 Predicted permease K07089 - - 0.000000001282 70.0
XH3_k127_73277_0 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000005479 151.0
XH3_k127_73277_1 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000004202 101.0
XH3_k127_73277_2 - - - - 0.000000000000001101 87.0
XH3_k127_7337940_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 581.0
XH3_k127_7337940_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 502.0
XH3_k127_7337940_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 298.0
XH3_k127_7337940_3 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001428 245.0
XH3_k127_7337940_4 - - - - 0.00006187 52.0
XH3_k127_7375686_0 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 2.207e-201 641.0
XH3_k127_7375686_1 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 538.0
XH3_k127_7375686_10 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 407.0
XH3_k127_7375686_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 377.0
XH3_k127_7375686_12 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 354.0
XH3_k127_7375686_13 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006208 354.0
XH3_k127_7375686_14 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 343.0
XH3_k127_7375686_15 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 344.0
XH3_k127_7375686_16 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 329.0
XH3_k127_7375686_17 glutamate synthase (NADPH) K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 327.0
XH3_k127_7375686_18 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000001061 272.0
XH3_k127_7375686_19 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001724 260.0
XH3_k127_7375686_2 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 501.0
XH3_k127_7375686_20 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000004296 244.0
XH3_k127_7375686_21 Iron-containing alcohol dehydrogenase K19954 - - 0.00000000000000000000000000000000000000000000000000000000000000004144 237.0
XH3_k127_7375686_22 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000008709 229.0
XH3_k127_7375686_23 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000009473 219.0
XH3_k127_7375686_24 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002859 221.0
XH3_k127_7375686_25 phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000006801 224.0
XH3_k127_7375686_26 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000003306 224.0
XH3_k127_7375686_27 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000009233 207.0
XH3_k127_7375686_28 PFAM purine or other phosphorylase, family 1 K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000001269 188.0
XH3_k127_7375686_29 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000002275 192.0
XH3_k127_7375686_3 Domain of unknown function (DUF1297) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 455.0
XH3_k127_7375686_30 with the TIM-barrel fold K07051 - - 0.000000000000000000000000000000000000000000442 168.0
XH3_k127_7375686_31 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.00000000000000000000000000000000000000005088 156.0
XH3_k127_7375686_32 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000003975 148.0
XH3_k127_7375686_33 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.000000000000000000000000000003395 138.0
XH3_k127_7375686_34 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000004328 119.0
XH3_k127_7375686_35 haloacid dehalogenase-like hydrolase K01091,K06019 - 3.1.3.18,3.6.1.1 0.00000000000000000000000001421 117.0
XH3_k127_7375686_36 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000005935 114.0
XH3_k127_7375686_37 Methionine synthase B12-binding module cap domain protein K00548,K14081,K16179 - 2.1.1.13 0.000000000000000000000000505 112.0
XH3_k127_7375686_38 Cyclophilin-like K09143 - - 0.00000000000000000000002326 103.0
XH3_k127_7375686_39 - - - - 0.00000000000000001083 87.0
XH3_k127_7375686_4 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 440.0
XH3_k127_7375686_40 Universal stress protein - - - 0.00000000000003112 78.0
XH3_k127_7375686_41 - - - - 0.0000000000000805 81.0
XH3_k127_7375686_42 Transcriptional regulator, TrmB - - - 0.0000000000001339 80.0
XH3_k127_7375686_43 DNA-directed RNA polymerases I, II, and III subunit K03014 GO:0000003,GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0005666,GO:0005730,GO:0005736,GO:0008150,GO:0016591,GO:0030880,GO:0031974,GO:0031981,GO:0032502,GO:0032991,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0055029,GO:0061695,GO:0070013,GO:1902494,GO:1990234 - 0.0000000000006159 76.0
XH3_k127_7375686_44 COG1522 Transcriptional regulators - - - 0.0000000000007236 71.0
XH3_k127_7375686_45 - - - - 0.00000000000182 72.0
XH3_k127_7375686_46 - - - - 0.000000000001961 77.0
XH3_k127_7375686_47 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000006606 64.0
XH3_k127_7375686_48 Mannose-6-phosphate isomerase K01485 - 3.5.4.1 0.0000000003705 66.0
XH3_k127_7375686_49 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000001413 66.0
XH3_k127_7375686_5 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 450.0
XH3_k127_7375686_50 S25 ribosomal protein K02975 - - 0.00000005012 58.0
XH3_k127_7375686_51 UPF0292 protein - - - 0.0000002806 58.0
XH3_k127_7375686_52 Belongs to the UPF0237 family K07166 - - 0.000001625 53.0
XH3_k127_7375686_53 COG1522 Transcriptional regulators - - - 0.00001145 50.0
XH3_k127_7375686_54 Lrp/AsnC ligand binding domain - - - 0.00002072 49.0
XH3_k127_7375686_55 Thioredoxin-like - - - 0.0002032 51.0
XH3_k127_7375686_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 423.0
XH3_k127_7375686_7 TIGRFAM dihydroorotate dehydrogenase family protein K17723 - 1.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 418.0
XH3_k127_7375686_8 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 418.0
XH3_k127_7375686_9 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 413.0
XH3_k127_7456_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 513.0
XH3_k127_7456_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 471.0
XH3_k127_7456_10 6-phosphogluconate dehydrogenase, NAD-binding K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 303.0
XH3_k127_7456_11 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000002214 247.0
XH3_k127_7456_12 phosphoesterase RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000008433 235.0
XH3_k127_7456_13 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002234 218.0
XH3_k127_7456_14 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.000000000000000000000000000000000000000000000000000000006947 210.0
XH3_k127_7456_15 Belongs to the LeuD family K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000001213 184.0
XH3_k127_7456_16 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000000001245 186.0
XH3_k127_7456_17 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000277 106.0
XH3_k127_7456_18 conserved protein implicated in secretion - - - 0.00000000000000000157 95.0
XH3_k127_7456_19 PFAM transcriptional regulator PadR family protein - - - 0.00000000000002181 80.0
XH3_k127_7456_2 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 447.0
XH3_k127_7456_20 lysine biosynthesis protein LysW K05826 - - 0.00000000001245 66.0
XH3_k127_7456_21 Rieske-like [2Fe-2S] domain - - - 0.0000000004605 66.0
XH3_k127_7456_22 Transcriptional regulator - - - 0.000000002035 70.0
XH3_k127_7456_23 Uncharacterised ACR, YggU family COG1872 K09131 - - 0.00000008038 57.0
XH3_k127_7456_24 - - - - 0.0001219 48.0
XH3_k127_7456_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 436.0
XH3_k127_7456_4 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 389.0
XH3_k127_7456_5 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 376.0
XH3_k127_7456_6 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 366.0
XH3_k127_7456_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 346.0
XH3_k127_7456_8 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 332.0
XH3_k127_7456_9 Lysine biosynthesis K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 311.0
XH3_k127_7576949_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 331.0
XH3_k127_7576949_1 AAA domain - - - 0.0000000000000006273 92.0
XH3_k127_7576949_2 AAA domain - - - 0.00000000000002357 87.0
XH3_k127_7669266_0 Arginase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007339 236.0
XH3_k127_7696736_0 Condensation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 553.0
XH3_k127_7758598_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 426.0
XH3_k127_7758598_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001065 253.0
XH3_k127_7758598_2 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000000000000000000000000004703 153.0
XH3_k127_7758598_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14091 - - 0.00000000000000000002733 94.0
XH3_k127_7758598_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000001787 87.0
XH3_k127_7758598_5 electron transfer activity K05337 - - 0.000000000001088 72.0
XH3_k127_7758598_6 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.00000000007862 68.0
XH3_k127_777598_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.905e-246 779.0
XH3_k127_777598_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003495 278.0
XH3_k127_777598_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000001289 233.0
XH3_k127_777598_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000007508 214.0
XH3_k127_777598_4 - - - - 0.0000000000000000000000000000000000000000000000000000002212 203.0
XH3_k127_777598_5 Methyltransferase type 11 - - - 0.0000000000000000000000006626 115.0
XH3_k127_777598_6 PFAM GYD family protein - - - 0.0006108 48.0
XH3_k127_777598_7 Protein of unknown function (DUF2493) - - - 0.0009772 47.0
XH3_k127_7877201_0 Belongs to the glycosyl hydrolase 57 family K06044 - 5.4.99.15 4.41e-203 643.0
XH3_k127_7877201_1 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 446.0
XH3_k127_7877201_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000008375 69.0
XH3_k127_7888881_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 7.109e-198 631.0
XH3_k127_7888881_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 522.0
XH3_k127_7888881_10 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000899 189.0
XH3_k127_7888881_11 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000007397 183.0
XH3_k127_7888881_12 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000005542 163.0
XH3_k127_7888881_13 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000001739 139.0
XH3_k127_7888881_14 PFAM metal-dependent phosphohydrolase HD sub domain K07023 - - 0.000000000000000000000169 105.0
XH3_k127_7888881_15 defense response to virus - - - 0.000000000000000001558 87.0
XH3_k127_7888881_16 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.000000000000001094 88.0
XH3_k127_7888881_17 integral membrane protein K07027 - - 0.00000000000003349 84.0
XH3_k127_7888881_18 PFAM Putitive phosphate transport regulator K07220 - - 0.000000005107 66.0
XH3_k127_7888881_19 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.000000008008 64.0
XH3_k127_7888881_2 Belongs to the HMG-CoA reductase family K00021,K00054 - 1.1.1.34,1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 452.0
XH3_k127_7888881_20 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000002746 56.0
XH3_k127_7888881_21 Methyl-coenzyme M reductase K03422 - - 0.00000509 53.0
XH3_k127_7888881_3 ATPases associated with a variety of cellular activities K00400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 457.0
XH3_k127_7888881_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 335.0
XH3_k127_7888881_5 methanogenesis marker protein 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 301.0
XH3_k127_7888881_6 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003999 292.0
XH3_k127_7888881_7 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000001311 249.0
XH3_k127_7888881_8 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.000000000000000000000000000000000000000000000000000000000000000000002512 242.0
XH3_k127_7888881_9 Methanogenesis marker protein 5 - - - 0.0000000000000000000000000000000000000000000000000000001206 198.0
XH3_k127_8062477_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000002169 237.0
XH3_k127_8062477_1 GPR1 FUN34 yaaH family protein K07034 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006835,GO:0006846,GO:0006855,GO:0008028,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015077,GO:0015078,GO:0015123,GO:0015238,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015355,GO:0015360,GO:0015672,GO:0015711,GO:0015718,GO:0015740,GO:0015744,GO:0015849,GO:0015893,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034220,GO:0035433,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0043893,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071422,GO:0071702,GO:0071944,GO:0098655,GO:0098656,GO:0098660,GO:0098662,GO:1902600,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000002749 168.0
XH3_k127_8062477_2 Phosphate uptake regulator - - - 0.00000000000000000000000000000000001009 149.0
XH3_k127_8062477_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000001624 93.0
XH3_k127_8185671_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 376.0
XH3_k127_8185671_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000009811 117.0
XH3_k127_8185671_2 COG1977 Molybdopterin converting factor, small subunit K03636 - - 0.0005261 46.0
XH3_k127_8193437_0 protein synthesis factor GTP-binding K03231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 489.0
XH3_k127_8193437_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 363.0
XH3_k127_8193437_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007164 276.0
XH3_k127_8193437_3 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.000000000000000000000000000000000000000000000000000000001871 209.0
XH3_k127_8193437_4 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.000000000000000000000000000000000000000001196 166.0
XH3_k127_8193437_5 - - - - 0.0000000000000000000000000000944 119.0
XH3_k127_8193437_6 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000002352 117.0
XH3_k127_8193437_7 Transcriptional regulator, TrmB - - - 0.00000000000004882 80.0
XH3_k127_8193437_8 GCN5-related N-acetyl-transferase K06975 - - 0.000000000002126 73.0
XH3_k127_8208526_0 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 431.0
XH3_k127_8208526_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000006198 192.0
XH3_k127_8208526_2 conserved protein implicated in secretion - - - 0.0000000000000000000000000001141 121.0
XH3_k127_821028_0 symporter activity K11928,K14392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 349.0
XH3_k127_821028_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000005981 225.0
XH3_k127_821028_2 hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000003255 149.0
XH3_k127_821028_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000854 153.0
XH3_k127_821028_4 PFAM nickel-dependent hydrogenase, large subunit K00436 - 1.12.1.2 0.000000000000009874 79.0
XH3_k127_8396777_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003732 273.0
XH3_k127_8396777_1 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000009727 132.0
XH3_k127_8396777_2 ECF-type riboflavin transporter, S component K16927 - - 0.00000000000000000000009857 105.0
XH3_k127_8396777_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000007908 74.0
XH3_k127_8414710_0 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003187 271.0
XH3_k127_8414710_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000559 232.0
XH3_k127_8414710_2 TIGRFAM methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.000000000000000000000000000000001092 143.0
XH3_k127_8414710_3 EamA-like transporter family - - - 0.000000000000000000001499 105.0
XH3_k127_8452775_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 408.0
XH3_k127_8452775_1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 396.0
XH3_k127_8452775_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 290.0
XH3_k127_8452775_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000006323 158.0
XH3_k127_8452775_4 Nitroreductase family - - - 0.000000000000000000000000000000000679 138.0
XH3_k127_8452775_5 PFAM PspC domain K03973 - - 0.00000000000000001205 92.0
XH3_k127_8452775_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000436 72.0
XH3_k127_8452775_7 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000007852 74.0
XH3_k127_8452775_8 threonine efflux protein - - - 0.0000000009091 61.0
XH3_k127_8464982_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 511.0
XH3_k127_8464982_1 ABC-type tungstate transport system, permease component K05772 - - 0.000000000000000000000000000000000000000000000000000000000000001537 229.0
XH3_k127_8464982_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000004406 223.0
XH3_k127_8464982_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000007913 209.0
XH3_k127_8464982_4 Thiamine-binding protein - - - 0.000000000000000000002934 98.0
XH3_k127_8464982_5 transcriptional regulator, ModE family K02019 - - 0.000000000000003133 81.0
XH3_k127_8464982_6 riboflavin transmembrane transporter activity - - - 0.000008774 55.0
XH3_k127_8464982_7 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 0.0003359 49.0
XH3_k127_8507919_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 336.0
XH3_k127_8507919_1 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 300.0
XH3_k127_8507919_2 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000001103 211.0
XH3_k127_8507919_3 marker protein 11 - - - 0.0000000000000000000000001066 110.0
XH3_k127_8514211_0 TIGRFAM cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000001177 142.0
XH3_k127_8514211_1 membrane - - - 0.000000000008022 70.0
XH3_k127_8514211_2 PFAM Major Facilitator Superfamily K08223 - - 0.000001371 60.0
XH3_k127_8514211_3 Type III restriction enzyme, res subunit K14635 GO:0000003,GO:0000018,GO:0000217,GO:0000278,GO:0000400,GO:0000714,GO:0000724,GO:0000725,GO:0000732,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007530,GO:0007531,GO:0007533,GO:0007535,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009378,GO:0009892,GO:0009987,GO:0010520,GO:0010564,GO:0010605,GO:0010639,GO:0010948,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0022402,GO:0022413,GO:0022414,GO:0022616,GO:0030154,GO:0031297,GO:0031323,GO:0031324,GO:0031974,GO:0031981,GO:0032392,GO:0032502,GO:0032505,GO:0032508,GO:0032991,GO:0033043,GO:0033260,GO:0033554,GO:0033567,GO:0033677,GO:0034641,GO:0034645,GO:0035861,GO:0036297,GO:0040020,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0044786,GO:0045003,GO:0045005,GO:0045128,GO:0045165,GO:0045786,GO:0045835,GO:0045910,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051276,GO:0051321,GO:0051445,GO:0051447,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060542,GO:0060543,GO:0060631,GO:0061982,GO:0065007,GO:0070013,GO:0070035,GO:0070336,GO:0071103,GO:0071704,GO:0071821,GO:0071840,GO:0071932,GO:0080090,GO:0090304,GO:0090734,GO:0097159,GO:0110029,GO:0140097,GO:0140098,GO:1901360,GO:1901363,GO:1901576,GO:1902346,GO:1902969,GO:1903046,GO:1903047,GO:1903461,GO:1990163,GO:2000241,GO:2000242 3.6.4.12 0.000008166 53.0
XH3_k127_8517710_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 358.0
XH3_k127_8517710_1 TIGRFAM F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000008297 204.0
XH3_k127_8517710_2 ASNC family K03718 - - 0.00000000000000000000000000000000000000123 152.0
XH3_k127_8527739_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.156e-277 876.0
XH3_k127_8527739_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 3.672e-228 728.0
XH3_k127_8527739_10 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000002418 190.0
XH3_k127_8527739_11 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000003846 183.0
XH3_k127_8527739_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000005921 179.0
XH3_k127_8527739_13 Belongs to the imidazoleglycerol-phosphate dehydratase family K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000002252 173.0
XH3_k127_8527739_14 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000235 176.0
XH3_k127_8527739_15 - - - - 0.000000000000000000000001427 116.0
XH3_k127_8527739_16 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000006445 100.0
XH3_k127_8527739_17 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000009521 79.0
XH3_k127_8527739_2 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 409.0
XH3_k127_8527739_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 344.0
XH3_k127_8527739_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 349.0
XH3_k127_8527739_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 338.0
XH3_k127_8527739_6 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000012 304.0
XH3_k127_8527739_7 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002467 282.0
XH3_k127_8527739_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000002493 225.0
XH3_k127_8527739_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000002 207.0
XH3_k127_8551431_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 424.0
XH3_k127_8551431_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 344.0
XH3_k127_8551431_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000001347 140.0
XH3_k127_8551431_3 Ribosomal protein S26e K02976 - - 0.0000000000000000000000001206 108.0
XH3_k127_8551431_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000001393 89.0
XH3_k127_8581907_0 Secreted protein with C-terminal beta-propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 363.0
XH3_k127_8581907_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 334.0
XH3_k127_8581907_2 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000007554 168.0
XH3_k127_8581907_3 ZPR1-like zinc finger protein K06874 - - 0.0000000000000000000000000009093 119.0
XH3_k127_8663458_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 370.0
XH3_k127_8663458_1 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008811 202.0
XH3_k127_8663458_10 Ribonuclease III - - - 0.0000000000000000013 91.0
XH3_k127_8663458_11 RNA polymerase Rpb3/Rpb11 dimerisation domain K03008 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0006139,GO:0006351,GO:0006353,GO:0006366,GO:0006369,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016591,GO:0018130,GO:0019438,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 - 0.000000000000008505 77.0
XH3_k127_8663458_12 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000001336 57.0
XH3_k127_8663458_2 Diphthamide K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000001323 207.0
XH3_k127_8663458_3 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000232 194.0
XH3_k127_8663458_4 Conserved hypothetical protein 95 K07579 - - 0.000000000000000000000000000000000000000000001769 172.0
XH3_k127_8663458_5 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000374 180.0
XH3_k127_8663458_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000008649 125.0
XH3_k127_8663458_7 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000001038 117.0
XH3_k127_8663458_8 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000000115 118.0
XH3_k127_8663458_9 Lysine methyltransferase K02493 - 2.1.1.297 0.0000000000000000000000000003986 123.0
XH3_k127_8664221_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 528.0
XH3_k127_8664221_1 - K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 380.0
XH3_k127_8664221_2 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 308.0
XH3_k127_8664221_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000008533 202.0
XH3_k127_8664221_4 Specifically catalyzes the decarboxylation of L-arginine to agmatine. Has no S-adenosylmethionine decarboxylase (AdoMetDC) activity K01611 - 4.1.1.50 0.000000000000000000000000000000000000000006433 157.0
XH3_k127_8664221_5 Winged helix-turn-helix - - - 0.0000000000000000000000224 107.0
XH3_k127_8664221_6 COGs COG3377 conserved - - - 0.00000000000000000003592 93.0
XH3_k127_8664221_7 PFAM cation antiporter K14110 - - 0.00000000000000004614 84.0
XH3_k127_8664221_8 - - - - 0.000000000000002671 83.0
XH3_k127_8664221_9 ribosomal protein S30 K02983 - - 0.000000000001275 68.0
XH3_k127_8692275_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000006682 213.0
XH3_k127_8692275_1 domain, Protein - - - 0.00000000009133 76.0
XH3_k127_875729_0 Cys/Met metabolism PLP-dependent enzyme K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 326.0
XH3_k127_875729_1 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000002215 141.0
XH3_k127_875729_2 QueT transporter - - - 0.000000000000005132 82.0
XH3_k127_875729_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000001287 57.0
XH3_k127_8765127_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000557 119.0
XH3_k127_8765127_1 domain, Protein K01200,K01226,K20276 - 3.2.1.41,3.2.1.93 0.000246 53.0
XH3_k127_8803519_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 451.0
XH3_k127_8803519_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 339.0
XH3_k127_8803519_10 Radical SAM superfamily - - - 0.0000000000000000004591 89.0
XH3_k127_8803519_11 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000001346 75.0
XH3_k127_8803519_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 329.0
XH3_k127_8803519_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 309.0
XH3_k127_8803519_4 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000009568 262.0
XH3_k127_8803519_5 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000001235 193.0
XH3_k127_8803519_6 PFAM PUA domain containing protein K07398 - - 0.0000000000000000000000000000000000000002121 155.0
XH3_k127_8803519_7 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000001247 149.0
XH3_k127_8803519_8 PFAM helix-turn-helix domain protein K03627 - - 0.000000000000000000000000005539 116.0
XH3_k127_8803519_9 PFAM CBS domain containing protein - - - 0.00000000000000000000002234 105.0
XH3_k127_8968035_0 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 314.0
XH3_k127_8968035_1 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.000000000000000000000000000000000000000000000000000000000000000000002197 253.0
XH3_k127_8968035_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000004803 242.0
XH3_k127_8968035_3 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000001764 94.0
XH3_k127_9017457_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.159e-200 636.0
XH3_k127_9017457_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 447.0
XH3_k127_9017457_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 310.0
XH3_k127_9017457_3 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000000000009516 214.0
XH3_k127_9017457_4 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000014 179.0
XH3_k127_9017457_5 Nitroreductase family K19285,K19286 - 1.5.1.38,1.5.1.39 0.0000000000000000000001028 108.0
XH3_k127_9017457_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000001091 93.0
XH3_k127_9017457_7 EamA-like transporter family - - - 0.00000000002896 74.0
XH3_k127_9131850_0 Glycosyl transferase family 2 - - - 0.00000000000000000000001377 111.0
XH3_k127_992597_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 346.0
XH3_k127_992597_1 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000004695 208.0
XH3_k127_992597_2 - - - - 0.00000000000000000000000000000000000000000000000000000006575 203.0
XH3_k127_992597_3 Trm112p-like protein - - - 0.00000000000000000000003576 102.0
XH3_k127_992597_4 chromatin protein, binds double-strand DNA without sequence specificity. Constrains negative DNA supercoils - - - 0.00000000002781 64.0
XH3_k127_992597_5 glutamine synthetase K01915 - 6.3.1.2 0.000000004619 57.0
XH3_k127_992597_6 Ferritin-like domain K03594 - 1.16.3.1 0.00002072 49.0