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Overview

ID MAG04467
Name YHH1_bin.30
Sample SMP0121
Taxonomy
Kingdom Archaea
Phylum Nanobdellota
Class Nanobdellia
Order Woesearchaeales
Family JAGWAF01
Genus
Species
Assembly information
Completeness (%) 85.98
Contamination (%) 0.38
GC content (%) 45.0
N50 (bp) 9,476
Genome size (bp) 1,004,799

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes726

Gene name Description KEGG GOs EC E-value Score Sequence
YHH1_k127_10005028_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 361.0
YHH1_k127_10005028_1 3-oxoacyl- acyl-carrier-protein reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000002288 221.0
YHH1_k127_10005028_2 Raf kinase inhibitor-like protein, YbhB YbcL family K06910 - - 0.0000000000000000000000000000000000000000000003984 174.0
YHH1_k127_10005028_3 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000009375 154.0
YHH1_k127_10005028_4 Transcriptional regulator, XRE family - - - 0.000000000000000000000000000000465 128.0
YHH1_k127_10005028_5 Fic/DOC family - - - 0.00000000000000000000000000004356 118.0
YHH1_k127_10005028_6 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000001371 125.0
YHH1_k127_10192702_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000004271 173.0
YHH1_k127_10192702_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000001686 123.0
YHH1_k127_10192702_3 PFAM zinc iron permease K16267 - - 0.000001963 51.0
YHH1_k127_10237551_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 410.0
YHH1_k127_10237551_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000572 230.0
YHH1_k127_10237551_2 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000002032 199.0
YHH1_k127_10334569_0 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002164 285.0
YHH1_k127_10334569_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001252 275.0
YHH1_k127_10334569_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000004288 235.0
YHH1_k127_10334569_3 COG1361 S-layer domain - - - 0.000000000000000000000000004629 126.0
YHH1_k127_10334569_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000771 76.0
YHH1_k127_10453484_0 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000174 127.0
YHH1_k127_10453484_1 PFAM regulatory protein AsnC Lrp family K03718 - - 0.0000000001135 68.0
YHH1_k127_10453484_2 pentapeptide repeat protein - - - 0.00004727 54.0
YHH1_k127_10526746_0 Catalyzes the synthesis of xanthosine monophosphate by the NAD dependent oxidation of inosine monophosphate K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000003753 194.0
YHH1_k127_10526746_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000004045 114.0
YHH1_k127_10548626_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 313.0
YHH1_k127_10548626_1 Thioredoxin - - - 0.0003164 52.0
YHH1_k127_10596664_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 344.0
YHH1_k127_10596664_1 COG0639 Diadenosine tetraphosphatase and related - - - 0.0000000000000000000000000000000000002811 153.0
YHH1_k127_10596664_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000002179 119.0
YHH1_k127_10596664_3 SNARE associated Golgi protein - - - 0.000000007796 57.0
YHH1_k127_10715652_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 376.0
YHH1_k127_10715652_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 334.0
YHH1_k127_10715652_10 N-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000002588 62.0
YHH1_k127_10715652_11 SpoVT / AbrB like domain - - - 0.000002527 59.0
YHH1_k127_10715652_12 - - - - 0.0008835 45.0
YHH1_k127_10715652_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001791 212.0
YHH1_k127_10715652_3 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000003336 175.0
YHH1_k127_10715652_4 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000002297 170.0
YHH1_k127_10715652_5 replication factor A K07466 - - 0.000000000000000000000000000000001231 142.0
YHH1_k127_10715652_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000003175 126.0
YHH1_k127_10715652_7 TRAM domain - - - 0.00000000000000001362 88.0
YHH1_k127_10715652_8 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000002521 79.0
YHH1_k127_10715652_9 PFAM regulatory protein AsnC Lrp family K03718 - - 0.0000000002787 67.0
YHH1_k127_10741655_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 329.0
YHH1_k127_10741655_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 339.0
YHH1_k127_10741655_2 TIGRFAM thymidylate synthase, methanogen type K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000003784 198.0
YHH1_k127_10741655_3 ATPase associated with various cellular activities AAA_5 K03405 - 6.6.1.1 0.0000000000000000000000000000007038 135.0
YHH1_k127_10741655_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000007303 124.0
YHH1_k127_10741655_5 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000001139 122.0
YHH1_k127_10741655_6 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000002865 121.0
YHH1_k127_10741655_7 PFAM metallophosphoesterase K07096 - - 0.000000000000000001461 95.0
YHH1_k127_10741655_8 Putative glutamine amidotransferase - - - 0.00000000126 70.0
YHH1_k127_10769204_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 5.027e-257 815.0
YHH1_k127_10769204_1 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 319.0
YHH1_k127_10769204_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002919 288.0
YHH1_k127_10769204_3 NOL1 NOP2 sun family - - - 0.00000000000000000000000000000000000000000000000000002161 198.0
YHH1_k127_10769204_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000004915 165.0
YHH1_k127_10769204_5 Ethanolamine utilization protein EutJ K01999 - - 0.0000000000000000000000000000805 129.0
YHH1_k127_10769204_6 Transcriptional regulator, TrmB - - - 0.0000000000000001141 89.0
YHH1_k127_10769204_7 PUA domain K07565 - - 0.0000001245 60.0
YHH1_k127_10791197_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 385.0
YHH1_k127_10791197_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 383.0
YHH1_k127_10791197_10 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000008111 183.0
YHH1_k127_10791197_12 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000522 151.0
YHH1_k127_10791197_13 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000004886 120.0
YHH1_k127_10791197_14 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products K03552 - 3.1.22.4 0.0000000000000000000000000008741 117.0
YHH1_k127_10791197_15 EamA-like transporter family - - - 0.0000000000000000000000001501 118.0
YHH1_k127_10791197_16 Transcriptional regulator - - - 0.00000000000000000007331 99.0
YHH1_k127_10791197_17 transcription factor (CBF NF-Y) - - - 0.00000000000004952 75.0
YHH1_k127_10791197_18 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000000007435 82.0
YHH1_k127_10791197_19 PFAM PRC-barrel domain - - - 0.0003898 47.0
YHH1_k127_10791197_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 360.0
YHH1_k127_10791197_20 Endonuclease I - - - 0.0006645 53.0
YHH1_k127_10791197_3 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 359.0
YHH1_k127_10791197_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 350.0
YHH1_k127_10791197_5 peptidase M29 K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 322.0
YHH1_k127_10791197_6 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000002321 231.0
YHH1_k127_10791197_7 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000821 227.0
YHH1_k127_10791197_8 Conserved hypothetical protein 95 K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000001083 220.0
YHH1_k127_10791197_9 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000005625 195.0
YHH1_k127_10803462_0 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000427 135.0
YHH1_k127_10803462_1 CAAX protease self-immunity K07052 - - 0.00000001413 66.0
YHH1_k127_10891743_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000003327 170.0
YHH1_k127_10891743_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000006506 159.0
YHH1_k127_10891743_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000009291 92.0
YHH1_k127_10891743_3 Phosphate uptake regulator - - - 0.00000000004751 73.0
YHH1_k127_10891743_5 - - - - 0.00004365 55.0
YHH1_k127_1095318_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000002077 202.0
YHH1_k127_1095318_1 NUDIX domain K08310 - 3.6.1.67 0.0000000000000001578 85.0
YHH1_k127_1149016_0 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 415.0
YHH1_k127_1149016_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.00000000000000000000000000000000000000000000000000000000000000492 223.0
YHH1_k127_1149016_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000074 53.0
YHH1_k127_1428727_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 448.0
YHH1_k127_1428727_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 396.0
YHH1_k127_1428727_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000003368 199.0
YHH1_k127_1428727_11 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000003155 170.0
YHH1_k127_1428727_12 Exosome complex component K11600 GO:0000175,GO:0000176,GO:0000177,GO:0000178,GO:0000288,GO:0000291,GO:0000460,GO:0000785,GO:0000956,GO:0001558,GO:0002252,GO:0002376,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005730,GO:0005737,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006304,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0008334,GO:0008408,GO:0009056,GO:0009057,GO:0009605,GO:0009607,GO:0009615,GO:0009892,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016075,GO:0016180,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017091,GO:0019219,GO:0019222,GO:0019439,GO:0022613,GO:0030307,GO:0031123,GO:0031125,GO:0031126,GO:0031323,GO:0031329,GO:0031974,GO:0031981,GO:0032991,GO:0034427,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0035327,GO:0040008,GO:0042254,GO:0043144,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043487,GO:0043488,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0045006,GO:0045111,GO:0045927,GO:0046483,GO:0046700,GO:0048518,GO:0048519,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051607,GO:0051704,GO:0051707,GO:0060255,GO:0061013,GO:0065007,GO:0065008,GO:0070013,GO:0071025,GO:0071027,GO:0071028,GO:0071044,GO:0071051,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0098542,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1903311,GO:1905354 - 0.0000000000000000000000000000000000000005825 157.0
YHH1_k127_1428727_13 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000004522 98.0
YHH1_k127_1428727_14 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000004419 91.0
YHH1_k127_1428727_15 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.000000000000000000814 91.0
YHH1_k127_1428727_16 Domain of unknown function (DUF378) K09779 - - 0.00000000000002188 75.0
YHH1_k127_1428727_17 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000001402 79.0
YHH1_k127_1428727_18 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000008716 68.0
YHH1_k127_1428727_19 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.00000000001076 70.0
YHH1_k127_1428727_2 Von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 404.0
YHH1_k127_1428727_20 Phosphate uptake regulator - - - 0.000000001378 69.0
YHH1_k127_1428727_21 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.00000009391 60.0
YHH1_k127_1428727_22 Belongs to the PDCD5 family K06875 - - 0.0000004895 55.0
YHH1_k127_1428727_23 - - - - 0.000002392 58.0
YHH1_k127_1428727_24 radical SAM domain protein - - - 0.00003806 56.0
YHH1_k127_1428727_25 lipopolysaccharide transmembrane transporter activity - - - 0.00009374 51.0
YHH1_k127_1428727_26 - - - - 0.0009201 45.0
YHH1_k127_1428727_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 363.0
YHH1_k127_1428727_4 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004651 280.0
YHH1_k127_1428727_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000003573 245.0
YHH1_k127_1428727_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000001417 236.0
YHH1_k127_1428727_7 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.00000000000000000000000000000000000000000000000000000000000000002367 232.0
YHH1_k127_1428727_8 Phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000003208 216.0
YHH1_k127_1428727_9 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000003078 201.0
YHH1_k127_1447675_0 BRO family, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 343.0
YHH1_k127_1447675_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000001701 162.0
YHH1_k127_1447675_2 Orotidine 5''-phosphate decarboxylase K01591,K13421 - 2.4.2.10,4.1.1.23 0.000000000000000000000001313 108.0
YHH1_k127_1565375_0 geranylgeranyl reductase K00311 - 1.5.5.1 0.0000000000000000000000000000002548 137.0
YHH1_k127_1571520_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000005272 121.0
YHH1_k127_1571520_1 Phosphoribosyl synthetase-associated domain K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576 2.7.6.1 0.000001944 60.0
YHH1_k127_1571520_2 AAA-like domain K06915 - - 0.000176 44.0
YHH1_k127_1596085_0 TCP-1/cpn60 chaperonin family K22447 - - 6.955e-221 697.0
YHH1_k127_1689799_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.524e-199 642.0
YHH1_k127_1689799_1 SMART Elongator protein 3 MiaB NifB K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 428.0
YHH1_k127_1694021_0 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000002423 125.0
YHH1_k127_1694021_1 - - - - 0.0000000000000000000000000001203 126.0
YHH1_k127_1694021_2 Protein tyrosine kinase - - - 0.0002133 52.0
YHH1_k127_1694021_3 Protein kinase domain K08884 - 2.7.11.1 0.0007687 55.0
YHH1_k127_1715248_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000004347 156.0
YHH1_k127_1715248_1 Phosphoribosylglycinamide synthetase, C domain K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.000000000000000000000000000000006877 141.0
YHH1_k127_1791480_0 Thrombospondin type 3 repeat - - - 0.00006867 56.0
YHH1_k127_1831903_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K22446 - - 0.00000000000000000000000000000009151 127.0
YHH1_k127_1831903_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K03778 - 1.1.1.28 0.0000000000000000000000000002069 117.0
YHH1_k127_1831903_2 belongs to the nudix hydrolase family - - - 0.00000000001609 71.0
YHH1_k127_1831903_3 NUDIX domain - - - 0.00000000003699 72.0
YHH1_k127_1910089_0 arylsulfatase activity - - - 0.00000000000000000000000000000000000000001499 172.0
YHH1_k127_1982877_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.672e-233 752.0
YHH1_k127_1982877_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 1.111e-213 679.0
YHH1_k127_1982877_10 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.00000004569 57.0
YHH1_k127_1982877_11 RNA polymerase Rpb5, C-terminal domain K03013 GO:0000375,GO:0000377,GO:0000398,GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005665,GO:0005666,GO:0005730,GO:0005736,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006351,GO:0006352,GO:0006353,GO:0006354,GO:0006360,GO:0006361,GO:0006363,GO:0006366,GO:0006367,GO:0006368,GO:0006370,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0008150,GO:0008152,GO:0008380,GO:0008543,GO:0009058,GO:0009059,GO:0009301,GO:0009452,GO:0009719,GO:0009893,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0016070,GO:0016071,GO:0016073,GO:0016591,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019222,GO:0019438,GO:0023052,GO:0030880,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0033554,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0036260,GO:0040029,GO:0042221,GO:0042795,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044344,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044452,GO:0044464,GO:0045815,GO:0046483,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055029,GO:0060147,GO:0060255,GO:0060964,GO:0060966,GO:0060968,GO:0061695,GO:0065007,GO:0070013,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071704,GO:0071774,GO:0090304,GO:0097659,GO:0097747,GO:0098781,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 - 0.00000007741 57.0
YHH1_k127_1982877_12 Domain of Unknown Function with PDB structure (DUF3850) - - - 0.0000906 49.0
YHH1_k127_1982877_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 424.0
YHH1_k127_1982877_3 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 317.0
YHH1_k127_1982877_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 299.0
YHH1_k127_1982877_5 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000195 185.0
YHH1_k127_1982877_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000005735 175.0
YHH1_k127_1982877_7 Ligand-binding protein K01999 - - 0.00000000000000000000000000000000001345 150.0
YHH1_k127_1982877_8 transcription termination protein NusA K02600 - - 0.00000000000000000005551 95.0
YHH1_k127_1982877_9 Transcriptional regulator, TrmB - - - 0.000000000000000001688 95.0
YHH1_k127_2062289_0 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.0000000000000000000000001101 120.0
YHH1_k127_2062289_1 - - - - 0.0000000000000000000003406 109.0
YHH1_k127_2062289_2 CYTH - - - 0.00000000009859 69.0
YHH1_k127_2062289_3 Domain of unknown function (DUF4349) - - - 0.0000001927 62.0
YHH1_k127_2193676_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 357.0
YHH1_k127_2193676_1 - - - - 0.0000000000000000001234 91.0
YHH1_k127_2193676_2 - K00960 - 2.7.7.6 0.0000000000001393 70.0
YHH1_k127_2204778_0 PFAM DNA polymerase, beta domain protein region - - - 0.0000000000000000000000000001886 124.0
YHH1_k127_2204778_1 Protein of unknown function (DUF2683) - - - 0.00000000000000002399 87.0
YHH1_k127_2204778_2 addiction module toxin, RelE StbE family - - - 0.000000000004231 69.0
YHH1_k127_2204778_3 deoxyribonuclease I activity K06131,K06915 - - 0.0001919 53.0
YHH1_k127_2212581_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000001335 270.0
YHH1_k127_2212581_1 - - - - 0.0000000000000308 79.0
YHH1_k127_2298247_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000001013 239.0
YHH1_k127_2298247_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000007708 216.0
YHH1_k127_2298247_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000004777 85.0
YHH1_k127_2298247_3 Phosphate uptake regulator - - - 0.00008862 53.0
YHH1_k127_2327079_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 512.0
YHH1_k127_2327079_1 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000002136 247.0
YHH1_k127_2327079_2 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000425 203.0
YHH1_k127_2327079_3 Protein of unknown function (DUF1648) - - - 0.000000000000000000000000000000000005372 144.0
YHH1_k127_2327079_4 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000009821 70.0
YHH1_k127_2327079_5 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000001026 58.0
YHH1_k127_2327079_6 Pfam:DUF552 K09152 - - 0.00003064 52.0
YHH1_k127_2327079_7 - - - - 0.0002378 45.0
YHH1_k127_2409049_0 Cell division protein 48, CDC48, domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 587.0
YHH1_k127_2409049_1 GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 408.0
YHH1_k127_2409049_10 COG3364 Zn-ribbon containing protein K07163 - - 0.0002896 45.0
YHH1_k127_2409049_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 356.0
YHH1_k127_2409049_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 336.0
YHH1_k127_2409049_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000455 203.0
YHH1_k127_2409049_5 Diguanylate cyclase with GAF sensor - - - 0.00000000000000000000000000000000000000000000001954 190.0
YHH1_k127_2409049_6 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000005877 161.0
YHH1_k127_2409049_7 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000002571 142.0
YHH1_k127_2409049_8 Phosphate uptake regulator, PhoU - - - 0.000000000000000000001226 106.0
YHH1_k127_2409049_9 DHHA1 domain K07463 - - 0.00002604 56.0
YHH1_k127_2469452_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 387.0
YHH1_k127_2469452_1 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
YHH1_k127_2469452_2 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000004585 85.0
YHH1_k127_2469452_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.000004514 51.0
YHH1_k127_2665646_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 475.0
YHH1_k127_2665646_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 376.0
YHH1_k127_2665646_2 nitroreductase K04719 - 1.13.11.79 0.000000000000000000000000000000000000003802 154.0
YHH1_k127_2698295_0 Bacterial regulatory protein, arsR family - - - 0.000000000004607 72.0
YHH1_k127_2698295_1 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.000000001237 65.0
YHH1_k127_2698295_2 Putative zinc- or iron-chelating domain K06940 - - 0.00002338 53.0
YHH1_k127_2830541_0 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 354.0
YHH1_k127_2830541_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 361.0
YHH1_k127_2830541_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 295.0
YHH1_k127_2904662_0 PFAM zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000002152 228.0
YHH1_k127_2904662_1 - - - - 0.000000000000000000001896 106.0
YHH1_k127_2958353_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 355.0
YHH1_k127_2958353_1 Rubrerythrin K19824 - - 0.0000000000000002976 81.0
YHH1_k127_3091371_0 Flavin reductase like domain - - - 0.000000000000000000000000129 112.0
YHH1_k127_3091371_1 PFAM Methyltransferase type 11 - - - 0.00000000001591 71.0
YHH1_k127_314320_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.066e-237 747.0
YHH1_k127_314320_1 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 306.0
YHH1_k127_314320_10 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000001008 75.0
YHH1_k127_314320_11 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000002223 60.0
YHH1_k127_314320_12 COG1522 Transcriptional regulators - - - 0.000000004553 60.0
YHH1_k127_314320_13 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000002012 59.0
YHH1_k127_314320_14 Transglutaminase-like superfamily - - - 0.00000002085 64.0
YHH1_k127_314320_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000006652 237.0
YHH1_k127_314320_3 DNA-directed RNA polymerase, subunit E K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000005284 190.0
YHH1_k127_314320_4 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000001843 169.0
YHH1_k127_314320_5 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001877 173.0
YHH1_k127_314320_6 Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000005717 152.0
YHH1_k127_314320_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000019 108.0
YHH1_k127_314320_8 archaeal coiled-coil protein - - - 0.000000000000001726 87.0
YHH1_k127_314320_9 Fcf1 K07158 - - 0.00000000000000304 80.0
YHH1_k127_3172833_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000003207 208.0
YHH1_k127_3172833_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000003307 169.0
YHH1_k127_3172833_2 Psort location Cytoplasmic, score 8.87 K02503 - - 0.000000000000000000000000953 115.0
YHH1_k127_3172833_3 Rhs Family - - - 0.000000000001605 79.0
YHH1_k127_3172833_4 CRS1_YhbY K07574 - - 0.00000001073 60.0
YHH1_k127_3334927_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000005232 209.0
YHH1_k127_3334927_1 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000001415 188.0
YHH1_k127_3334927_2 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000002042 137.0
YHH1_k127_3334927_3 PFAM ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000003572 104.0
YHH1_k127_3357146_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 341.0
YHH1_k127_3357146_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000003348 201.0
YHH1_k127_3357146_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000003789 173.0
YHH1_k127_3357146_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000000000208 94.0
YHH1_k127_3357146_4 - - - - 0.000000001675 63.0
YHH1_k127_3358335_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 349.0
YHH1_k127_3358335_1 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
YHH1_k127_3358335_2 Component of the EKC KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016604,GO:0016607,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0070013,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000003391 140.0
YHH1_k127_3358335_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0001744 49.0
YHH1_k127_3358335_4 Fructose-bisphosphate aldolase class-II K01192,K01624 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009277,GO:0009435,GO:0009605,GO:0009607,GO:0009986,GO:0009987,GO:0016020,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030312,GO:0030446,GO:0031347,GO:0031349,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035821,GO:0042866,GO:0043167,GO:0043169,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044003,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044403,GO:0044416,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0048518,GO:0048583,GO:0048584,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052251,GO:0052255,GO:0052509,GO:0052510,GO:0055086,GO:0055114,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0065007,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0075136,GO:0080134,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.2.1.25,4.1.2.13 0.0007743 49.0
YHH1_k127_3532120_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000000000000000000000000002582 213.0
YHH1_k127_3532120_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000001855 165.0
YHH1_k127_3606152_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K22446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001667 269.0
YHH1_k127_3606152_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000001657 84.0
YHH1_k127_3702812_0 Protein of unknown function (DUF2937) - - - 0.000000000000000000000002265 110.0
YHH1_k127_3702812_1 COG3911 Predicted ATPase - - - 0.0000000000000000000004758 102.0
YHH1_k127_3702812_2 Controls S-phase checkpoint as well as G1 and G2 DNA damage checkpoints. Phosphorylates proteins on serine, threonine, and tyrosine. Prevents entry into anaphase and mitotic exit after DNA damage via regulation of the Polo kinase CDC5 K06641 - 2.7.11.1 0.000000000000225 81.0
YHH1_k127_3702812_3 Domain of unknown function (DUF362) - - - 0.0004518 52.0
YHH1_k127_3706665_0 Belongs to the glycosyl hydrolase 43 family K20276 - - 0.000000000000006723 85.0
YHH1_k127_3718336_0 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000000007718 123.0
YHH1_k127_3718336_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000007457 63.0
YHH1_k127_3753865_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004916 291.0
YHH1_k127_3753865_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000005645 97.0
YHH1_k127_3754339_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000001038 187.0
YHH1_k127_3754339_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000002167 85.0
YHH1_k127_3754339_2 Methyltransferase domain - - - 0.000000000006261 73.0
YHH1_k127_3754339_3 Presenilin, signal peptide peptidase, family - - - 0.00000008868 62.0
YHH1_k127_388520_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 447.0
YHH1_k127_388520_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000002891 100.0
YHH1_k127_388520_2 Fibronectin type III domain - - - 0.0004124 52.0
YHH1_k127_3901989_0 Methyltransferase small domain - - - 0.000001774 59.0
YHH1_k127_3970095_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000005146 161.0
YHH1_k127_3970095_1 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.000000000000000000000000000000000000009824 152.0
YHH1_k127_401519_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 303.0
YHH1_k127_401519_1 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000004138 151.0
YHH1_k127_401519_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000000000000000001722 123.0
YHH1_k127_4064461_0 PFAM PP-loop - - - 0.00000000000000000000000000000000000000000000002917 181.0
YHH1_k127_4064461_1 assembly protein, NifU family K04488 - - 0.00000000000000000000000000000000000000000003951 166.0
YHH1_k127_4064461_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000009978 93.0
YHH1_k127_4064461_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000007449 60.0
YHH1_k127_4065504_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 300.0
YHH1_k127_4065504_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000002883 95.0
YHH1_k127_4166866_0 peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 432.0
YHH1_k127_4166866_1 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000001544 180.0
YHH1_k127_4166866_2 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000001541 108.0
YHH1_k127_4174293_0 DNA polymerase K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 571.0
YHH1_k127_4174293_1 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.0000000000000000000432 91.0
YHH1_k127_4174293_2 Thiopurine S-methyltransferase (TPMT) K16868 - 2.1.1.265 0.000000001019 67.0
YHH1_k127_4189692_0 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 3.849e-265 832.0
YHH1_k127_4189692_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000004114 224.0
YHH1_k127_4189692_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000005677 184.0
YHH1_k127_4189692_3 MafB19-like deaminase K01493 GO:0003674,GO:0003824,GO:0004132,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006231,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009157,GO:0009162,GO:0009165,GO:0009176,GO:0009177,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046073,GO:0046078,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.12 0.00000000000000000000000000000009311 130.0
YHH1_k127_4189692_4 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000001131 66.0
YHH1_k127_4228775_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 423.0
YHH1_k127_4228775_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000009114 219.0
YHH1_k127_4228775_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000002838 66.0
YHH1_k127_4228775_3 transcription regulator activity - - - 0.00001802 56.0
YHH1_k127_4233118_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K18105 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001742 285.0
YHH1_k127_4233118_1 Transcriptional regulator, TrmB - - - 0.0009762 49.0
YHH1_k127_4233774_0 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000001352 181.0
YHH1_k127_4233774_1 Glycogen debranching enzyme N terminal - - - 0.000000000000002498 90.0
YHH1_k127_4233774_2 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000122 48.0
YHH1_k127_4234757_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000173 196.0
YHH1_k127_4234757_1 Transport permease protein K01992 - - 0.0000006041 61.0
YHH1_k127_4336845_0 Cell division protein 48 (CDC48) N-terminal domain K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 458.0
YHH1_k127_4346686_0 PFAM proteinase inhibitor I4 serpin K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 376.0
YHH1_k127_4346686_1 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 290.0
YHH1_k127_4346686_2 DNA recombination-mediator protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000376 244.0
YHH1_k127_4346686_3 DHHA2 domain protein K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000006402 233.0
YHH1_k127_4346686_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000862 64.0
YHH1_k127_4392793_0 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000001784 160.0
YHH1_k127_4392793_1 AAA domain - - - 0.00000000000000000000000000000001361 133.0
YHH1_k127_4392793_2 Protein of unknown function (DUF460) K09150 - - 0.00000000000000000000000003847 122.0
YHH1_k127_4392793_3 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.0000000000000000000000005133 107.0
YHH1_k127_4392793_4 Transcriptional regulator - - - 0.0000000000000002072 83.0
YHH1_k127_4392793_5 mRNA decay K07562 - - 0.00000000000002618 78.0
YHH1_k127_4392793_6 metallopeptidase activity - - - 0.0000000000002995 73.0
YHH1_k127_4392793_7 Methyltransferase type 11 - - - 0.0000000006386 70.0
YHH1_k127_4392793_8 TIGRFAM signal peptidase I, archaeal type K13280 - 3.4.21.89 0.000000008995 64.0
YHH1_k127_4392793_9 Belongs to the UPF0235 family K09131 - - 0.00000008984 57.0
YHH1_k127_4517969_0 phosphopyruvate hydratase activity K01689 GO:0000003,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0019953,GO:0022414,GO:0044424,GO:0044464,GO:0044703,GO:0051704 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 498.0
YHH1_k127_4517969_1 SMART Elongator protein 3 MiaB NifB K06935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006931 262.0
YHH1_k127_4517969_11 - - - - 0.00000234 50.0
YHH1_k127_4517969_12 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000005895 55.0
YHH1_k127_4517969_13 protein conserved in archaea K09723 - - 0.000005963 57.0
YHH1_k127_4517969_14 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000006353 50.0
YHH1_k127_4517969_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000001224 184.0
YHH1_k127_4517969_3 PAC2 family K07159 - - 0.00000000000000000000000000000000000001484 154.0
YHH1_k127_4517969_4 transmembrane transport - - - 0.0000000000000000542 89.0
YHH1_k127_4517969_5 Ribosomal protein S27E K02978 - - 0.0000000000000003099 80.0
YHH1_k127_4517969_7 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.000000000000004721 77.0
YHH1_k127_4517969_8 binds to the 23S rRNA K02929 - - 0.000000000000318 73.0
YHH1_k127_4590044_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 383.0
YHH1_k127_4590044_1 Belongs to the peptidase S16 family K06870 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000003582 154.0
YHH1_k127_4762896_0 Putative diphthamide synthesis protein K07561 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016765,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0048037,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0051536,GO:0051539,GO:0051540,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.5.1.108 0.0000000000001773 74.0
YHH1_k127_4762896_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000004082 56.0
YHH1_k127_4875245_0 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000000000000002814 229.0
YHH1_k127_4875245_1 Translin family - - - 0.0000000000000000000000000001519 122.0
YHH1_k127_4943408_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 392.0
YHH1_k127_4943408_1 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000008662 164.0
YHH1_k127_4943408_2 AAA domain - - - 0.00000000000000000000000000002165 124.0
YHH1_k127_5362584_0 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000001474 212.0
YHH1_k127_5362584_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000004341 95.0
YHH1_k127_5362584_2 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000001364 68.0
YHH1_k127_5362584_3 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.0000000003042 64.0
YHH1_k127_5397097_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 477.0
YHH1_k127_5397097_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 462.0
YHH1_k127_5397097_10 Glutaredoxin - - - 0.000000000000000000001587 96.0
YHH1_k127_5397097_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 388.0
YHH1_k127_5397097_3 actin binding K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 290.0
YHH1_k127_5397097_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000015 218.0
YHH1_k127_5397097_5 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000006954 177.0
YHH1_k127_5397097_6 Thioredoxin - - - 0.00000000000000000000000000000000000000000004178 167.0
YHH1_k127_5397097_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000009372 143.0
YHH1_k127_5397097_8 Thioredoxin - - - 0.000000000000000000000000000000000001121 147.0
YHH1_k127_5397097_9 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000008018 115.0
YHH1_k127_5538883_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 466.0
YHH1_k127_5538883_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 334.0
YHH1_k127_5538883_2 NHL repeat containing protein - - - 0.00000000000000000000000000000002107 148.0
YHH1_k127_5538883_3 Protein-disulfide isomerase - - - 0.0000000000000000000000000000000301 138.0
YHH1_k127_5538883_4 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000001855 71.0
YHH1_k127_5538883_5 - - - - 0.00000008472 55.0
YHH1_k127_5600389_0 ABC-type multidrug transport system ATPase component - - - 0.00000000000000000000000000000000000000000000000000003396 201.0
YHH1_k127_5600389_1 PFAM helix-turn-helix domain protein K03627 - - 0.00000000000000001483 88.0
YHH1_k127_5600389_2 mRNA catabolic process - - - 0.000000000002489 74.0
YHH1_k127_575682_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.053e-284 892.0
YHH1_k127_5768696_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 392.0
YHH1_k127_5768696_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000001434 246.0
YHH1_k127_5768696_2 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000005583 223.0
YHH1_k127_5768696_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000001241 220.0
YHH1_k127_5868326_0 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003404 280.0
YHH1_k127_5868326_1 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002382 251.0
YHH1_k127_5868326_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000001055 244.0
YHH1_k127_5868326_3 transport system permease K01997 - - 0.000000000000000000000000000000000000000000000000002383 188.0
YHH1_k127_5868326_4 Transcriptional regulator, TrmB - - - 0.0000000000000000000000002675 115.0
YHH1_k127_5868326_5 Transcriptional regulator, TrmB - - - 0.00001351 55.0
YHH1_k127_587283_0 - - - - 0.0000000000000000000000000000000000000001993 167.0
YHH1_k127_587283_1 DNA-binding protein K06933 - - 0.000000000002701 67.0
YHH1_k127_5921652_0 Heat shock 70 kDa protein K04043 - - 1.855e-244 766.0
YHH1_k127_5921652_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000002591 124.0
YHH1_k127_6024107_0 N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000003328 254.0
YHH1_k127_6024107_1 Diguanylate cyclase - - - 0.00000000000000000000000000001263 129.0
YHH1_k127_6024107_2 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000003612 88.0
YHH1_k127_6024107_3 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000003142 79.0
YHH1_k127_6208598_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 597.0
YHH1_k127_6208598_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 534.0
YHH1_k127_6208598_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 379.0
YHH1_k127_6208598_3 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 294.0
YHH1_k127_6208598_4 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000006093 186.0
YHH1_k127_6208598_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000002088 164.0
YHH1_k127_6208598_6 SMART KH domain protein K06961 - - 0.00000000000000000000000000000000000000002173 160.0
YHH1_k127_6208598_7 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.000000000000000000000000000000000000001031 161.0
YHH1_k127_6208598_8 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000005563 158.0
YHH1_k127_6208598_9 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000008425 123.0
YHH1_k127_6222564_0 S-adenosylmethionine synthetase K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 520.0
YHH1_k127_6222564_1 BRO family, N-terminal domain K14623 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 310.0
YHH1_k127_6222564_2 Cytochrome C biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000001716 226.0
YHH1_k127_6222564_3 MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000547 85.0
YHH1_k127_6222564_4 PFAM Bile acid sodium symporter K03453 - - 0.00000513 57.0
YHH1_k127_634829_0 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 352.0
YHH1_k127_634829_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 301.0
YHH1_k127_634829_2 mannose-1-phosphate guanylyltransferase activity K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007151 281.0
YHH1_k127_634829_3 - - - - 0.000000004147 63.0
YHH1_k127_6433282_0 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000002624 229.0
YHH1_k127_6433282_1 TIGRFAM Competence protein ComEA, helix-hairpin-helix K17717 - 3.1.4.4 0.0000000000000000000000007637 110.0
YHH1_k127_6433282_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000000000003462 79.0
YHH1_k127_6433282_3 Belongs to the TtcA family K21947 - 2.8.1.15 0.0001691 51.0
YHH1_k127_6581836_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 339.0
YHH1_k127_6581836_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000297 208.0
YHH1_k127_6581836_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides K01465 - 3.5.2.3 0.000000000000000000257 93.0
YHH1_k127_6732706_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 493.0
YHH1_k127_6732706_1 C-terminal region of MMR_HSR1 domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008791 397.0
YHH1_k127_6732706_10 nucleotide metabolic process - - - 0.00000000004825 72.0
YHH1_k127_6732706_11 Belongs to the UPF0147 family K09721 - - 0.000000008589 59.0
YHH1_k127_6732706_12 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000006057 49.0
YHH1_k127_6732706_13 Mechanosensitive ion channel K16052 - - 0.0001376 51.0
YHH1_k127_6732706_14 Tetratricopeptide TPR_2 repeat protein - - - 0.0009656 49.0
YHH1_k127_6732706_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 321.0
YHH1_k127_6732706_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000004648 225.0
YHH1_k127_6732706_4 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000001131 198.0
YHH1_k127_6732706_5 TIGRFAM RNA methyltransferase, TrmH - - - 0.0000000000000000000000000000000000000000002993 166.0
YHH1_k127_6732706_6 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000004583 135.0
YHH1_k127_6732706_7 RNA-binding PUA-like domain of methyltransferase RsmF - - - 0.00000000000000000001837 96.0
YHH1_k127_6732706_8 ribosomal protein K02921 - - 0.0000000000000000003999 90.0
YHH1_k127_6732706_9 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000005015 76.0
YHH1_k127_6957087_0 helicase K03724 - - 1.38e-308 971.0
YHH1_k127_6957087_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 372.0
YHH1_k127_6957087_2 Peptidase M50 - - - 0.000000000000000000000000000000000000000001527 164.0
YHH1_k127_6957087_3 Flavodoxin-like fold - - - 0.00000000000000000000131 102.0
YHH1_k127_6957087_4 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.000000000000000003112 91.0
YHH1_k127_6957087_5 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000006792 91.0
YHH1_k127_6962104_0 PAC2 family K06869 - - 0.0000000000000000000000000000003196 133.0
YHH1_k127_7055313_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.00000000000000000000000000000000001557 145.0
YHH1_k127_7055313_1 PFAM histidine triad (HIT) protein K02503 - - 0.0000000000000000000002626 103.0
YHH1_k127_7055313_2 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.0000000632 63.0
YHH1_k127_7055313_3 Virulence protein RhuM family - - - 0.0000006007 57.0
YHH1_k127_7067620_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 563.0
YHH1_k127_7067620_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 316.0
YHH1_k127_7067620_2 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000005275 237.0
YHH1_k127_7067620_3 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000001681 227.0
YHH1_k127_7067620_4 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000003491 132.0
YHH1_k127_7067620_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000006276 60.0
YHH1_k127_7067620_6 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0002641 50.0
YHH1_k127_726194_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.57e-207 658.0
YHH1_k127_726194_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000117 247.0
YHH1_k127_726194_2 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000008783 243.0
YHH1_k127_726194_3 TIGRFAM RecB family nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000001144 230.0
YHH1_k127_726194_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000005688 212.0
YHH1_k127_726194_5 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000005898 139.0
YHH1_k127_726194_6 PFAM multiple antibiotic resistance (MarC)-related K05595 - - 0.0000000000000000000000000001589 121.0
YHH1_k127_726194_7 COG1994 Zn-dependent proteases - - - 0.000000000001688 75.0
YHH1_k127_726194_8 hemolysin K09712 - - 0.0000000007963 70.0
YHH1_k127_726194_9 Copper binding proteins, plastocyanin/azurin family - - - 0.0002068 51.0
YHH1_k127_7284093_0 oxidized base lesion DNA N-glycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000007894 201.0
YHH1_k127_7284093_1 - - - - 0.000000000000000000000000000000002157 132.0
YHH1_k127_7284093_2 PFAM DNA polymerase, beta domain protein region - - - 0.000000000000000000000000001315 130.0
YHH1_k127_7284093_3 - - - - 0.00000000000000000000001518 102.0
YHH1_k127_7284093_4 - - - - 0.0000000000000000399 85.0
YHH1_k127_7284093_5 - - - - 0.00002134 51.0
YHH1_k127_7284093_6 Sigma-54 interaction domain K07713,K07714 - - 0.00008444 52.0
YHH1_k127_7428900_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 315.0
YHH1_k127_7428900_1 NeuB family K03856,K13853 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002622 268.0
YHH1_k127_7428900_2 aminopeptidase N - - - 0.00001086 54.0
YHH1_k127_744156_0 K homology RNA-binding domain K06865 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 578.0
YHH1_k127_744156_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 440.0
YHH1_k127_744156_2 AAA ATPase domain - - - 0.00000000000000000005315 96.0
YHH1_k127_7493835_0 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000007718 184.0
YHH1_k127_7493835_1 Involved in protein export K03074 - - 0.000000000000000000000000000000000000001227 155.0
YHH1_k127_7563069_0 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000272 261.0
YHH1_k127_7563069_3 zinc metalloprotease whose natural substrate is K06974 - - 0.0002224 51.0
YHH1_k127_7583070_0 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000882 162.0
YHH1_k127_7583070_1 Rubrerythrin K19824 - - 0.0000000000000000000000000000000004264 138.0
YHH1_k127_7583070_2 protein maturation K02224,K13628,K15724 - 6.3.5.11,6.3.5.9 0.000000000000004739 80.0
YHH1_k127_7583070_3 Rubrerythrin - - - 0.000000000005141 66.0
YHH1_k127_7583070_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000005596 66.0
YHH1_k127_7603281_0 ERCC4 domain K10896 - - 8.97e-208 670.0
YHH1_k127_7603281_1 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 406.0
YHH1_k127_7603281_10 Pheromone shutdown protein - - - 0.00000000000000000000000000000000002044 146.0
YHH1_k127_7603281_11 PHP domain protein - - - 0.00000000000000000000000000000000002179 143.0
YHH1_k127_7603281_12 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001958 94.0
YHH1_k127_7603281_13 cellulose binding - - - 0.0000000000171 79.0
YHH1_k127_7603281_14 PFAM acid phosphatase vanadium-dependent haloperoxidase related K09775 - - 0.0000000002006 66.0
YHH1_k127_7603281_15 PFAM peptidase M50 - - - 0.000000002409 67.0
YHH1_k127_7603281_16 transcriptional - - - 0.00000009134 62.0
YHH1_k127_7603281_17 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00001871 57.0
YHH1_k127_7603281_18 PRC-barrel domain - - - 0.00002038 50.0
YHH1_k127_7603281_19 COG3209 Rhs family protein - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.0004222 55.0
YHH1_k127_7603281_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005189 284.0
YHH1_k127_7603281_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000482 271.0
YHH1_k127_7603281_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000006508 232.0
YHH1_k127_7603281_5 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000003759 244.0
YHH1_k127_7603281_6 PFAM LemA - - - 0.00000000000000000000000000000000000000000000000000002132 194.0
YHH1_k127_7603281_7 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000004744 193.0
YHH1_k127_7603281_8 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000004592 155.0
YHH1_k127_7603281_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000001142 145.0
YHH1_k127_7607633_0 UPF0313 protein - - - 0.000000000000000000002222 99.0
YHH1_k127_7615443_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 454.0
YHH1_k127_7615443_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 433.0
YHH1_k127_7615443_2 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002052 294.0
YHH1_k127_7615443_3 Putative metal-binding motif - - - 0.00000000000000000000000000000000000000000000003513 196.0
YHH1_k127_7615443_4 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000006079 173.0
YHH1_k127_7615443_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000003103 131.0
YHH1_k127_7615443_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000005082 113.0
YHH1_k127_7615443_7 PFAM Diphthamide synthesis DPH2 protein K07561 GO:0006417,GO:0006448,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:2000112,GO:2000765 2.5.1.108 0.00000000000002406 76.0
YHH1_k127_7697858_0 Periplasmic copper-binding protein (NosD) - - - 0.0000005089 61.0
YHH1_k127_7871273_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 597.0
YHH1_k127_7871273_1 4Fe-4S single cluster domain K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008805 269.0
YHH1_k127_7871273_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000001212 218.0
YHH1_k127_7871273_3 hydrolase, TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000767 173.0
YHH1_k127_7871273_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000114 119.0
YHH1_k127_7871273_5 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000001666 111.0
YHH1_k127_7871273_6 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000001795 102.0
YHH1_k127_7871273_7 Involved in regulation of DNA replication K10725 - - 0.0000000000000002996 87.0
YHH1_k127_7883843_0 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 424.0
YHH1_k127_7883843_1 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 355.0
YHH1_k127_7883843_10 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain - - - 0.0000000184 59.0
YHH1_k127_7883843_2 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000151 248.0
YHH1_k127_7883843_3 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000003925 249.0
YHH1_k127_7883843_4 ABC transporter K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000001292 227.0
YHH1_k127_7883843_5 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000005745 204.0
YHH1_k127_7883843_6 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000001693 161.0
YHH1_k127_7883843_7 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000006579 152.0
YHH1_k127_7883843_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000008131 87.0
YHH1_k127_7883843_9 PFAM Oligosaccharyl transferase STT3 subunit K21306 - 2.4.99.21 0.00000000000002822 86.0
YHH1_k127_8003022_0 RimK-like ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000003488 199.0
YHH1_k127_8003022_1 Kinase domain protein K12132 - 2.7.11.1 0.00000000000000000002898 101.0
YHH1_k127_8003022_2 Phosphate uptake regulator - - - 0.000000000006326 76.0
YHH1_k127_8092824_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000008646 231.0
YHH1_k127_8092824_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000001592 225.0
YHH1_k127_8092824_2 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000006959 224.0
YHH1_k127_8092824_3 peptidase U32 K08303 - - 0.0000000000000000000000000000000000000006358 163.0
YHH1_k127_8092824_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000008754 112.0
YHH1_k127_8092824_5 S-layer homology domain - - - 0.00000000000000008976 90.0
YHH1_k127_8092824_6 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000002504 81.0
YHH1_k127_8092824_7 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000008426 60.0
YHH1_k127_8092824_8 PFAM Radical SAM domain protein K15045,K22227 - - 0.0000005242 61.0
YHH1_k127_8092824_9 transcriptional - - - 0.0003229 52.0
YHH1_k127_810301_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1113.0
YHH1_k127_810301_1 DeoC/LacD family aldolase K11645,K16305 - 2.2.1.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 287.0
YHH1_k127_810301_2 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 257.0
YHH1_k127_810301_3 COG0524 Sugar kinases, ribokinase family K00852,K00892 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008906,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237 2.7.1.15,2.7.1.73 0.0000000000000000000000000000000000000000000000000000000000009963 221.0
YHH1_k127_810301_4 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000001885 141.0
YHH1_k127_810301_6 - - - - 0.00003714 49.0
YHH1_k127_8115214_0 Peptidase S8 K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000002363 210.0
YHH1_k127_816754_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000004718 225.0
YHH1_k127_816754_1 duf431 domain-containing protein - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016273,GO:0016274,GO:0016740,GO:0016741,GO:0018193,GO:0018195,GO:0018216,GO:0019538,GO:0032259,GO:0035241,GO:0035246,GO:0035247,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000125 101.0
YHH1_k127_8194798_0 filamentous haemagglutinin family outer membrane protein K15125 - - 0.0000006305 55.0
YHH1_k127_8194798_1 PIN domain - - - 0.0005378 48.0
YHH1_k127_8233591_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002596 274.0
YHH1_k127_8291015_0 DNA topoisomerase II activity K02469 - 5.99.1.3 2.046e-304 957.0
YHH1_k127_8291015_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000007887 199.0
YHH1_k127_8291015_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000001843 93.0
YHH1_k127_8291015_11 segregation and condensation protein B K06024 - - 0.00000000000000004188 95.0
YHH1_k127_8291015_12 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000001171 86.0
YHH1_k127_8291015_13 MazG-like family - - - 0.0000000003387 64.0
YHH1_k127_8291015_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000003893 194.0
YHH1_k127_8291015_3 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000335 194.0
YHH1_k127_8291015_4 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000001859 183.0
YHH1_k127_8291015_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001093 150.0
YHH1_k127_8291015_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000004004 138.0
YHH1_k127_8291015_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000001381 130.0
YHH1_k127_8291015_8 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002953 123.0
YHH1_k127_8291015_9 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000004641 111.0
YHH1_k127_8312484_0 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002041 270.0
YHH1_k127_8433305_0 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 408.0
YHH1_k127_8433305_1 - - - - 0.000000000000000000000000000000000000001319 169.0
YHH1_k127_8433305_2 Transcriptional regulator K07722 - - 0.0009181 45.0
YHH1_k127_852745_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 461.0
YHH1_k127_852745_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002623 270.0
YHH1_k127_852745_2 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
YHH1_k127_852745_3 GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006477 245.0
YHH1_k127_852745_4 - - - - 0.0000000004979 63.0
YHH1_k127_853349_0 Serine threonine protein kinase - - - 0.000000000004876 75.0
YHH1_k127_8533667_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000009745 246.0
YHH1_k127_8533667_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.35 0.0000000000000000000000000000000000000000000000000000002137 208.0
YHH1_k127_8533667_2 Domain of unknown function (DUF4405) - - - 0.000000653 53.0
YHH1_k127_8533667_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000001101 58.0
YHH1_k127_8590529_0 Glycogen starch synthase K00693 GO:0000271,GO:0000272,GO:0003674,GO:0003824,GO:0004373,GO:0005488,GO:0005515,GO:0005536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005938,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005980,GO:0005981,GO:0006073,GO:0006091,GO:0006109,GO:0006112,GO:0006914,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008194,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009250,GO:0009251,GO:0009267,GO:0009605,GO:0009743,GO:0009744,GO:0009746,GO:0009749,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0009991,GO:0010033,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015629,GO:0015980,GO:0016051,GO:0016052,GO:0016236,GO:0016740,GO:0016757,GO:0016758,GO:0016772,GO:0019222,GO:0030246,GO:0030863,GO:0030864,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031667,GO:0031668,GO:0031669,GO:0032881,GO:0033554,GO:0033692,GO:0034284,GO:0034285,GO:0034637,GO:0034645,GO:0035251,GO:0036094,GO:0042221,GO:0042594,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043265,GO:0043467,GO:0043470,GO:0043471,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045819,GO:0045913,GO:0046527,GO:0046983,GO:0048029,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0060255,GO:0061547,GO:0061723,GO:0061912,GO:0061919,GO:0062012,GO:0062013,GO:0065007,GO:0070873,GO:0070875,GO:0070887,GO:0071310,GO:0071322,GO:0071324,GO:0071329,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0099568,GO:1901575,GO:1901576,GO:1901700,GO:1901701 2.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 439.0
YHH1_k127_8590529_1 Cupredoxin-like domain - - - 0.000000000000000007139 90.0
YHH1_k127_8605081_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 3.375e-242 768.0
YHH1_k127_8605081_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 582.0
YHH1_k127_8605081_11 Binds to the 23S rRNA K02896 - - 0.0000000000001043 74.0
YHH1_k127_8605081_12 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000001985 59.0
YHH1_k127_8605081_2 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000009334 188.0
YHH1_k127_8605081_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000003786 166.0
YHH1_k127_8605081_4 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000002122 145.0
YHH1_k127_8605081_5 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001179 122.0
YHH1_k127_8605081_6 Transcriptional regulator, TrmB - - - 0.0000000000000000000000004377 114.0
YHH1_k127_8605081_7 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000001618 88.0
YHH1_k127_8605081_8 Cupin 2, conserved barrel domain protein - - - 0.00000000000000001875 86.0
YHH1_k127_8605081_9 membrane - - - 0.000000000000009142 80.0
YHH1_k127_8642584_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 566.0
YHH1_k127_8642584_1 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000003488 230.0
YHH1_k127_8642584_2 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000012 155.0
YHH1_k127_8642584_3 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000001117 121.0
YHH1_k127_8642584_4 Transcriptional regulator, AsnC family K03719 - - 0.000000001228 69.0
YHH1_k127_8642584_5 helix_turn_helix ASNC type K03718 - - 0.0000003841 61.0
YHH1_k127_8642584_6 Putative ATP-dependant zinc protease - - - 0.0000005596 56.0
YHH1_k127_8642584_7 cheY-homologous receiver domain - - - 0.0003016 53.0
YHH1_k127_866456_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 345.0
YHH1_k127_866456_1 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005166 265.0
YHH1_k127_866456_2 ZPR1-like zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000163 135.0
YHH1_k127_866456_3 sigma factor antagonist activity K04757,K06379,K08282 - 2.7.11.1 0.00009894 49.0
YHH1_k127_8668813_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000008511 136.0
YHH1_k127_8668813_1 - - - - 0.0000000000000000000000001499 117.0
YHH1_k127_8668813_2 COG0025 NhaP-type Na H and K H antiporters - - - 0.00000000001013 77.0
YHH1_k127_8668813_3 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.0000000003111 64.0
YHH1_k127_8691801_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000001216 164.0
YHH1_k127_8691801_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000003533 115.0
YHH1_k127_8691801_2 Acetyltransferase (GNAT) family - - - 0.00007543 51.0
YHH1_k127_8698276_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 457.0
YHH1_k127_8698276_1 FMN binding - - - 0.0000000000000000000002121 100.0
YHH1_k127_8774043_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 336.0
YHH1_k127_8774043_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000001154 179.0
YHH1_k127_8774043_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000002752 169.0
YHH1_k127_8774043_3 Transglutaminase-like - - - 0.000000000000000004673 99.0
YHH1_k127_8774043_4 Transcriptional regulator - - - 0.00000001114 65.0
YHH1_k127_8785819_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 477.0
YHH1_k127_8785819_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000002231 85.0
YHH1_k127_8786670_0 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000003904 263.0
YHH1_k127_878716_0 tRNA (Uracil-5-)-methyltransferase - - - 0.000000000000000000000000000000000000000000000002993 179.0
YHH1_k127_878716_1 k transport K10716 - - 0.000006732 54.0
YHH1_k127_8965623_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001793 272.0
YHH1_k127_8965623_1 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000003808 227.0
YHH1_k127_8965623_2 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000002271 205.0
YHH1_k127_8965623_3 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000114 128.0
YHH1_k127_8965623_4 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000002708 120.0
YHH1_k127_8965623_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000003534 103.0
YHH1_k127_8965623_6 binds to the 23S rRNA K02922 - - 0.0000000000000000005381 87.0
YHH1_k127_8965623_7 Belongs to the snRNP Sm proteins family K04796 - - 0.0000000000000000006171 88.0
YHH1_k127_8965623_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000006658 69.0
YHH1_k127_8965623_9 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K06931 - - 0.0007889 49.0
YHH1_k127_8982598_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 366.0
YHH1_k127_8982598_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000008103 178.0
YHH1_k127_8982598_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000004045 179.0
YHH1_k127_8982598_3 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000149 76.0
YHH1_k127_8982598_4 ABC-2 family transporter protein K01992 - - 0.00000009246 55.0
YHH1_k127_8984130_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.746e-262 820.0
YHH1_k127_9058632_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 382.0
YHH1_k127_9058632_1 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00000000000003511 83.0
YHH1_k127_9058632_2 Acetyltransferase GNAT family - - - 0.00002044 53.0
YHH1_k127_9094287_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.346e-222 717.0
YHH1_k127_9094287_1 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005006 278.0
YHH1_k127_9094287_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000001596 207.0
YHH1_k127_9094287_3 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000000000000000000000002449 151.0
YHH1_k127_9094287_4 PFAM Glycosyl transferases group 1 K19002 - 2.4.1.337 0.000000000000000000000004021 115.0
YHH1_k127_9094287_5 proteins, LmbE homologs K01463 - - 0.0000000000002419 78.0
YHH1_k127_9094287_6 Protein of unknown function (DUF456) K09793 - - 0.0000000004385 67.0
YHH1_k127_9094287_7 LAGLIDADG-like domain K07500 - - 0.000002806 58.0
YHH1_k127_9094287_8 DHHA1 domain K07463 - - 0.0007815 51.0
YHH1_k127_9313185_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 1.373e-302 968.0
YHH1_k127_9313185_1 Belongs to the MCM family K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 516.0
YHH1_k127_9313185_10 Integral membrane protein DUF106 - - - 0.00000007624 63.0
YHH1_k127_9313185_11 PQQ-like domain - - - 0.000447 53.0
YHH1_k127_9313185_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 413.0
YHH1_k127_9313185_3 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000198 242.0
YHH1_k127_9313185_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000005177 194.0
YHH1_k127_9313185_5 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000003799 144.0
YHH1_k127_9313185_6 binds to the 23S rRNA K02876 - - 0.0000000000000002509 86.0
YHH1_k127_9313185_7 Protein of unknown function (DUF424) K09148 - - 0.0000000000000002705 81.0
YHH1_k127_9313185_8 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000006798 74.0
YHH1_k127_9313185_9 helicase activity - - - 0.00000000002806 72.0
YHH1_k127_9317857_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 8.079e-252 812.0
YHH1_k127_9317857_1 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.000000000000000000000000000000000000000000002065 175.0
YHH1_k127_9317857_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000002803 164.0
YHH1_k127_9317857_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate - - - 0.00000000000000000000000000000000003476 140.0
YHH1_k127_9317857_4 Domain of unknown function (DUF4416) - - - 0.000000000000000000000004738 108.0
YHH1_k127_9317857_5 Thymidylate kinase K13809 GO:0002237,GO:0003674,GO:0003824,GO:0004127,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010033,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0032496,GO:0033862,GO:0033993,GO:0034641,GO:0034654,GO:0042221,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0055086,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071396,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701 2.7.4.14 0.00000000000000001913 89.0
YHH1_k127_9317857_6 - K15383 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0042802,GO:0044425 - 0.000000387 56.0
YHH1_k127_9317857_7 Haloacid dehalogenase-like hydrolase K07025,K20866 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050308 3.1.3.10 0.00004773 53.0
YHH1_k127_9317857_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0003476 48.0
YHH1_k127_9455673_0 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007468 284.0
YHH1_k127_9455673_1 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000003982 179.0
YHH1_k127_9455673_2 - - - - 0.0000003592 53.0
YHH1_k127_9455673_3 Mediates influx of magnesium ions K03284 - - 0.0005505 50.0
YHH1_k127_9535904_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 402.0
YHH1_k127_9535904_1 (ABC) transporter K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000006778 227.0
YHH1_k127_9535904_2 Transcriptional regulator, TrmB - - - 0.000000000000008384 84.0
YHH1_k127_9535904_3 ABC transporter K02049,K15555 - - 0.0000000002588 62.0
YHH1_k127_9535904_4 dUTPase K01494 - 3.5.4.13 0.0001172 44.0
YHH1_k127_956915_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000004533 145.0
YHH1_k127_956915_1 subfamily IA, variant 3 - - - 0.0000000000000000000000000001921 123.0
YHH1_k127_956915_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.0000000000000000000001176 98.0
YHH1_k127_956915_3 - K00960 - 2.7.7.6 0.00000000000072 68.0
YHH1_k127_956915_4 4Fe-4S binding domain K05796 - - 0.000001183 52.0
YHH1_k127_9587749_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 612.0
YHH1_k127_9587749_1 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000002864 211.0
YHH1_k127_9587749_2 PFAM S-layer - - - 0.000000000000000000000000000000000000000000000000001802 194.0
YHH1_k127_9587749_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000333 189.0
YHH1_k127_9587749_4 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000000002196 167.0
YHH1_k127_9587749_5 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000002981 78.0
YHH1_k127_9617558_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000026 214.0
YHH1_k127_9617558_1 Transcriptional regulator, BadM Rrf2 family - - - 0.0000000000000000000000000000000000000000007 161.0
YHH1_k127_9617558_2 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000341 98.0
YHH1_k127_965014_0 Belongs to the phosphoglycerate mutase family K02226,K22305 - 3.1.3.3,3.1.3.73 0.00000000000000000000000003165 116.0
YHH1_k127_965014_1 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.00000000000000000000061 107.0
YHH1_k127_965014_2 Belongs to the Nudix hydrolase family - - - 0.00000000000006698 75.0
YHH1_k127_965014_3 Phosphate uptake regulator, PhoU - - - 0.00000000002598 74.0
YHH1_k127_965014_4 Pentapeptide repeats (9 copies) - - - 0.0000000001842 70.0
YHH1_k127_965014_5 Transcriptional regulator K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0001707 49.0
YHH1_k127_9677260_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 413.0
YHH1_k127_9677260_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 389.0
YHH1_k127_9677260_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000002999 217.0
YHH1_k127_9677260_3 protein catabolic process K03420,K13525,K17681 - - 0.00000000000000000000000000000000496 145.0
YHH1_k127_9677260_4 serine threonine protein kinase - - - 0.00000000000000001424 98.0
YHH1_k127_9677260_5 of the AAA class - - - 0.00000000007736 75.0
YHH1_k127_9677260_6 Transcriptional regulator, TrmB - - - 0.0000001153 62.0
YHH1_k127_9677260_7 Right handed beta helix region - - - 0.0009634 51.0
YHH1_k127_9727427_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 1.656e-270 863.0
YHH1_k127_9727427_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 387.0
YHH1_k127_9727427_2 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001392 243.0
YHH1_k127_9727427_3 Protein of unknown function DUF84 - - - 0.000000000000000000000000000000000000299 146.0
YHH1_k127_9727427_4 - - - - 0.000000003952 63.0
YHH1_k127_9755571_0 Glycosyl hydrolases family 15 K07190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 308.0
YHH1_k127_9755571_1 ROK family K00845 - 2.7.1.2 0.0000000000004387 71.0
YHH1_k127_9855478_0 Beta-Casp domain K07041 - - 1.554e-208 665.0
YHH1_k127_9855478_1 COG0058 Glucan phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 513.0
YHH1_k127_9855478_10 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00005724 46.0
YHH1_k127_9855478_11 Domain of Unknown Function with PDB structure (DUF3850) - - - 0.0001663 48.0
YHH1_k127_9855478_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 492.0
YHH1_k127_9855478_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007815 377.0
YHH1_k127_9855478_4 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001582 263.0
YHH1_k127_9855478_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000001503 168.0
YHH1_k127_9855478_6 Pyrimidine dimer DNA glycosylase K01161 - 3.1.25.1 0.0000000000000000000009754 100.0
YHH1_k127_9855478_7 CYTH - - - 0.00000000000000000003649 96.0
YHH1_k127_9855478_8 Hydrolase, NUDIX family - - - 0.0000000000000000001281 93.0
YHH1_k127_9855478_9 Signal peptidase K13280 - 3.4.21.89 0.0000007594 58.0
YHH1_k127_9974294_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 326.0
YHH1_k127_9974294_1 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 325.0
YHH1_k127_9974294_2 MGS-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007494 228.0
YHH1_k127_9974294_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.0000000000000000000000000000004443 135.0
YHH1_k127_9974294_4 COG0150 Phosphoribosylaminoimidazole (AIR) synthetase K01933 - 6.3.3.1 0.00000000000000000000000000000982 134.0
YHH1_k127_9974294_5 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000001072 93.0
YHH1_k127_9974294_6 PFAM Oligosaccharyl transferase STT3 subunit K21306 - 2.4.99.21 0.000000000001719 79.0