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Overview

ID MAG04481
Name YHH1_bin.51
Sample SMP0121
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order E44-bin15
Family E44-bin15
Genus
Species
Assembly information
Completeness (%) 59.88
Contamination (%) 1.15
GC content (%) 57.0
N50 (bp) 19,538
Genome size (bp) 1,141,456

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1059

Gene name Description KEGG GOs EC E-value Score Sequence
YHH1_k127_10191298_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.904e-222 699.0
YHH1_k127_10191298_1 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000005978 235.0
YHH1_k127_10191298_10 - - - - 0.0000001998 55.0
YHH1_k127_10191298_2 KH domain K06346 - - 0.000000000000000000000000000000000000000000000007269 180.0
YHH1_k127_10191298_3 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000001083 162.0
YHH1_k127_10191298_4 - - - - 0.00000000000000000000000000009337 116.0
YHH1_k127_10191298_5 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000003405 108.0
YHH1_k127_10191298_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000001198 101.0
YHH1_k127_10191298_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000375 105.0
YHH1_k127_10191298_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000003635 79.0
YHH1_k127_10191298_9 - - - - 0.00000001079 58.0
YHH1_k127_10198997_0 Belongs to the N(4) N(6)-methyltransferase family K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 317.0
YHH1_k127_10198997_1 PFAM Bacterial regulatory proteins, lacI family - - - 0.000000000000000000000000000000000000000008516 158.0
YHH1_k127_10198997_2 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000006912 138.0
YHH1_k127_10198997_3 - - - - 0.00004342 49.0
YHH1_k127_10345063_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.144e-251 786.0
YHH1_k127_10345063_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 7.074e-225 706.0
YHH1_k127_10345063_10 - - - - 0.0000000006687 70.0
YHH1_k127_10345063_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 9.718e-223 702.0
YHH1_k127_10345063_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 619.0
YHH1_k127_10345063_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 473.0
YHH1_k127_10345063_5 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 382.0
YHH1_k127_10345063_6 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000007444 218.0
YHH1_k127_10345063_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000344 184.0
YHH1_k127_10345063_8 MgtC family K07507 - - 0.00000000000000000000000000000007025 129.0
YHH1_k127_10345063_9 zinc finger - - - 0.0000000000002062 78.0
YHH1_k127_1040936_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 6.181e-196 620.0
YHH1_k127_1040936_1 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 402.0
YHH1_k127_1040936_11 RDD family - - - 0.00000000000000000001232 95.0
YHH1_k127_1040936_12 PFAM Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000008506 92.0
YHH1_k127_1040936_13 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002018 85.0
YHH1_k127_1040936_14 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000002184 91.0
YHH1_k127_1040936_15 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000265 83.0
YHH1_k127_1040936_16 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000003108 58.0
YHH1_k127_1040936_17 Protein of unknown function (DUF2892) - - - 0.00001049 50.0
YHH1_k127_1040936_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 314.0
YHH1_k127_1040936_3 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
YHH1_k127_1040936_4 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002273 265.0
YHH1_k127_1040936_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001327 258.0
YHH1_k127_1040936_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000007037 212.0
YHH1_k127_1040936_7 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000003656 211.0
YHH1_k127_1040936_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000001614 155.0
YHH1_k127_1040936_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000004577 149.0
YHH1_k127_10630122_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.514e-290 916.0
YHH1_k127_10630122_1 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 273.0
YHH1_k127_10630122_3 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.0000000000000000000000001088 108.0
YHH1_k127_10630122_4 cell adhesion K11904 - - 0.00000000000000000000001191 111.0
YHH1_k127_10630122_5 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000000000000009381 92.0
YHH1_k127_10717158_0 Glycine radical K00656 - 2.3.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 606.0
YHH1_k127_10717158_1 DegT/DnrJ/EryC1/StrS aminotransferase family K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000482 492.0
YHH1_k127_10717158_10 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000001159 112.0
YHH1_k127_10717158_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000002207 85.0
YHH1_k127_10717158_13 Transcriptional regulator - - - 0.00001048 57.0
YHH1_k127_10717158_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 468.0
YHH1_k127_10717158_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 422.0
YHH1_k127_10717158_4 Dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006898 334.0
YHH1_k127_10717158_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 312.0
YHH1_k127_10717158_6 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 301.0
YHH1_k127_10717158_7 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007785 271.0
YHH1_k127_10717158_8 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000211 256.0
YHH1_k127_10717158_9 MaoC like domain - - - 0.000000000000000000000000000002201 125.0
YHH1_k127_1105950_0 AAA-like domain K06915 - - 7.732e-201 643.0
YHH1_k127_1105950_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.102e-198 645.0
YHH1_k127_1105950_10 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 325.0
YHH1_k127_1105950_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 320.0
YHH1_k127_1105950_12 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 329.0
YHH1_k127_1105950_13 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008614 270.0
YHH1_k127_1105950_14 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000009995 256.0
YHH1_k127_1105950_15 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001985 250.0
YHH1_k127_1105950_16 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003408 273.0
YHH1_k127_1105950_17 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000009676 246.0
YHH1_k127_1105950_18 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000008388 241.0
YHH1_k127_1105950_19 Molybdenum cofactor synthesis domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003227 223.0
YHH1_k127_1105950_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 555.0
YHH1_k127_1105950_20 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000004046 218.0
YHH1_k127_1105950_21 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000001015 194.0
YHH1_k127_1105950_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000001472 187.0
YHH1_k127_1105950_23 PFAM HAS barrel domain - - - 0.000000000000000000000000000000000000000000000000008863 192.0
YHH1_k127_1105950_24 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000003857 150.0
YHH1_k127_1105950_25 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000001506 141.0
YHH1_k127_1105950_26 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000002824 140.0
YHH1_k127_1105950_27 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000000002047 136.0
YHH1_k127_1105950_28 Small Multidrug Resistance protein K03297 - - 0.000000000000000000000000000003537 122.0
YHH1_k127_1105950_29 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000001352 126.0
YHH1_k127_1105950_3 chorismate binding enzyme K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 516.0
YHH1_k127_1105950_30 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000008886 111.0
YHH1_k127_1105950_31 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000156 108.0
YHH1_k127_1105950_32 - - - - 0.000003616 57.0
YHH1_k127_1105950_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 490.0
YHH1_k127_1105950_5 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 362.0
YHH1_k127_1105950_6 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 344.0
YHH1_k127_1105950_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 339.0
YHH1_k127_1105950_8 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 331.0
YHH1_k127_1105950_9 NurA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 334.0
YHH1_k127_1406831_0 SMART Elongator protein 3 MiaB NifB - - - 2.635e-248 779.0
YHH1_k127_1406831_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 441.0
YHH1_k127_1406831_10 - - - - 0.000000000000000512 79.0
YHH1_k127_1406831_11 PFAM glycosyl transferase family 39 - - - 0.0000001026 58.0
YHH1_k127_1406831_2 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 334.0
YHH1_k127_1406831_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001265 288.0
YHH1_k127_1406831_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002931 281.0
YHH1_k127_1406831_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004769 265.0
YHH1_k127_1406831_6 PFAM thioesterase superfamily protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000008247 131.0
YHH1_k127_1406831_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.0000000000000000000000000000005669 128.0
YHH1_k127_1406831_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000002272 108.0
YHH1_k127_1406831_9 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000144 81.0
YHH1_k127_1530974_0 malic enzyme K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 466.0
YHH1_k127_1530974_1 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 292.0
YHH1_k127_1530974_10 - - - - 0.00000000001455 72.0
YHH1_k127_1530974_11 - - - - 0.0000000008562 68.0
YHH1_k127_1530974_12 - - - - 0.0000259 51.0
YHH1_k127_1530974_13 Archaeal Type IV pilin, N-terminal - - - 0.00004549 54.0
YHH1_k127_1530974_14 Psort location Cytoplasmic, score - - - 0.000458 48.0
YHH1_k127_1530974_2 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 304.0
YHH1_k127_1530974_3 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001832 256.0
YHH1_k127_1530974_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003418 229.0
YHH1_k127_1530974_5 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000004562 227.0
YHH1_k127_1530974_6 His Kinase A (phosphoacceptor) domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000002157 244.0
YHH1_k127_1530974_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000006331 241.0
YHH1_k127_1530974_8 - - - - 0.0000000000000000000000000000000000000000000000004236 180.0
YHH1_k127_1530974_9 - - - - 0.000000000006502 73.0
YHH1_k127_1577489_0 Dak1_2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 408.0
YHH1_k127_1577489_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 370.0
YHH1_k127_1810252_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 2.31e-283 876.0
YHH1_k127_1810252_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002093 280.0
YHH1_k127_1842172_0 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 525.0
YHH1_k127_1842172_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 442.0
YHH1_k127_1842172_10 HD domain - - - 0.00000000000000000000000001902 126.0
YHH1_k127_1842172_11 PFAM Glutaredoxin K06191 - - 0.000000000000000000000001248 105.0
YHH1_k127_1842172_12 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000001395 105.0
YHH1_k127_1842172_13 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000002028 101.0
YHH1_k127_1842172_14 Phosphoesterase K07095 - - 0.00000000000000000000004813 106.0
YHH1_k127_1842172_15 PFAM response regulator receiver K07657 - - 0.00000000000000000000008787 106.0
YHH1_k127_1842172_16 CAAX protease self-immunity K07052 - - 0.000000000000000000001446 103.0
YHH1_k127_1842172_17 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000003713 98.0
YHH1_k127_1842172_18 - - - - 0.0000000000000000007449 86.0
YHH1_k127_1842172_19 flavin adenine dinucleotide binding - - - 0.000000000000000002455 94.0
YHH1_k127_1842172_2 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 449.0
YHH1_k127_1842172_20 Carboxypeptidase regulatory-like domain - - - 0.0000000003256 72.0
YHH1_k127_1842172_22 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00008836 55.0
YHH1_k127_1842172_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 444.0
YHH1_k127_1842172_4 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 330.0
YHH1_k127_1842172_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 316.0
YHH1_k127_1842172_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 287.0
YHH1_k127_1842172_7 WLM domain K07043 - - 0.000000000000000000000000000000000000000000000000000000000003465 215.0
YHH1_k127_1842172_8 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000002319 179.0
YHH1_k127_1842172_9 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.000000000000000000000000000000000000003897 149.0
YHH1_k127_1911386_0 Conserved region in glutamate synthase - - - 1.811e-272 843.0
YHH1_k127_1911386_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 2.441e-248 790.0
YHH1_k127_1911386_10 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 366.0
YHH1_k127_1911386_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 354.0
YHH1_k127_1911386_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 358.0
YHH1_k127_1911386_13 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 351.0
YHH1_k127_1911386_14 PFAM glutamate synthase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 331.0
YHH1_k127_1911386_15 Phage integrase, N-terminal SAM-like domain K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 334.0
YHH1_k127_1911386_16 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 323.0
YHH1_k127_1911386_17 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 309.0
YHH1_k127_1911386_18 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 294.0
YHH1_k127_1911386_19 Formyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 293.0
YHH1_k127_1911386_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.902e-227 718.0
YHH1_k127_1911386_20 Belongs to the enoyl-CoA hydratase isomerase family K07546 - - 0.000000000000000000000000000000000000000000000000000000000000000000002205 243.0
YHH1_k127_1911386_21 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000009423 248.0
YHH1_k127_1911386_22 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000001379 243.0
YHH1_k127_1911386_23 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
YHH1_k127_1911386_24 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000003749 233.0
YHH1_k127_1911386_25 4Fe-4S dicluster domain K00196 - - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
YHH1_k127_1911386_26 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000007526 204.0
YHH1_k127_1911386_27 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000001337 202.0
YHH1_k127_1911386_28 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000000000000000007736 204.0
YHH1_k127_1911386_29 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000001461 181.0
YHH1_k127_1911386_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 8.308e-219 685.0
YHH1_k127_1911386_30 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000405 183.0
YHH1_k127_1911386_31 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000000000000000000000000000000000000000007959 179.0
YHH1_k127_1911386_33 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000609 151.0
YHH1_k127_1911386_34 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000003979 145.0
YHH1_k127_1911386_36 SMART Nucleotide binding protein, PINc K07063 - - 0.00000000000000002647 87.0
YHH1_k127_1911386_37 peptidase inhibitor activity K01406 - 3.4.24.40 0.00000000000001365 89.0
YHH1_k127_1911386_38 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000485 68.0
YHH1_k127_1911386_39 Transglutaminase-like superfamily - - - 0.000000001414 67.0
YHH1_k127_1911386_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 5.122e-218 691.0
YHH1_k127_1911386_40 otolith morphogenesis - - - 0.000000011 66.0
YHH1_k127_1911386_41 Helix-turn-helix domain - - - 0.000001824 53.0
YHH1_k127_1911386_5 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 586.0
YHH1_k127_1911386_6 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 542.0
YHH1_k127_1911386_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 455.0
YHH1_k127_1911386_8 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 449.0
YHH1_k127_1911386_9 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 437.0
YHH1_k127_2006258_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1369.0
YHH1_k127_2006258_1 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1142.0
YHH1_k127_2006258_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006905 481.0
YHH1_k127_2006258_11 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 443.0
YHH1_k127_2006258_12 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 434.0
YHH1_k127_2006258_13 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 447.0
YHH1_k127_2006258_14 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 432.0
YHH1_k127_2006258_15 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 398.0
YHH1_k127_2006258_16 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008204 395.0
YHH1_k127_2006258_17 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 380.0
YHH1_k127_2006258_18 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 372.0
YHH1_k127_2006258_19 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 348.0
YHH1_k127_2006258_2 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 7.927e-303 945.0
YHH1_k127_2006258_20 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 344.0
YHH1_k127_2006258_21 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 312.0
YHH1_k127_2006258_22 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 309.0
YHH1_k127_2006258_23 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 296.0
YHH1_k127_2006258_24 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006818 284.0
YHH1_k127_2006258_25 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001182 254.0
YHH1_k127_2006258_26 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 248.0
YHH1_k127_2006258_27 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
YHH1_k127_2006258_28 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
YHH1_k127_2006258_29 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000008106 211.0
YHH1_k127_2006258_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 4.85e-282 878.0
YHH1_k127_2006258_30 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000003627 179.0
YHH1_k127_2006258_31 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000001349 174.0
YHH1_k127_2006258_32 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000007938 161.0
YHH1_k127_2006258_33 Transposase - - - 0.0000000000000000000000000000000000000002665 160.0
YHH1_k127_2006258_34 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000001468 151.0
YHH1_k127_2006258_35 enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.000000000000000000000000000000000003008 149.0
YHH1_k127_2006258_36 - - - - 0.000000000000000000000000000000006403 132.0
YHH1_k127_2006258_37 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000009362 136.0
YHH1_k127_2006258_38 TM2 domain - - - 0.0000000000000000000000000008018 115.0
YHH1_k127_2006258_39 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K20453 - 4.2.1.33,4.2.1.35,4.2.1.85 0.00000000000000000000000001677 110.0
YHH1_k127_2006258_4 Domain of unknown function (DUF1998) K06877 - - 5.946e-264 833.0
YHH1_k127_2006258_40 HNH endonuclease - - - 0.000000000000000000000003336 108.0
YHH1_k127_2006258_41 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000004423 99.0
YHH1_k127_2006258_42 Bacterial transcription activator, effector binding domain - - - 0.000000000000000000001385 100.0
YHH1_k127_2006258_43 TM2 domain - - - 0.000000000000000000004514 97.0
YHH1_k127_2006258_44 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000002159 97.0
YHH1_k127_2006258_45 NADPH-dependent FMN reductase - - - 0.000000000000000005804 93.0
YHH1_k127_2006258_47 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000004795 54.0
YHH1_k127_2006258_48 PBS lyase HEAT-like repeat - - - 0.000007082 57.0
YHH1_k127_2006258_49 Hydantoinase/oxoprolinase N-terminal region - - - 0.00003188 47.0
YHH1_k127_2006258_5 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.598e-223 702.0
YHH1_k127_2006258_50 Armadillo/beta-catenin-like repeats - - - 0.0003034 46.0
YHH1_k127_2006258_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 535.0
YHH1_k127_2006258_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 511.0
YHH1_k127_2006258_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 513.0
YHH1_k127_2006258_9 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 502.0
YHH1_k127_2060355_0 COG1520 FOG WD40-like repeat K17713 - - 0.0000000000000005207 89.0
YHH1_k127_2153085_0 Heat shock 70 kDa protein K04043 - - 2.095e-311 964.0
YHH1_k127_2153085_1 FAD dependent oxidoreductase K05898 - 1.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 488.0
YHH1_k127_2153085_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000003238 184.0
YHH1_k127_2153085_11 BioY family K03523 - - 0.000000000000000000000000000000000000000000000002872 179.0
YHH1_k127_2153085_12 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000001587 160.0
YHH1_k127_2153085_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000003611 159.0
YHH1_k127_2153085_14 Beta-lactamase superfamily domain - - - 0.0000585 47.0
YHH1_k127_2153085_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 473.0
YHH1_k127_2153085_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 392.0
YHH1_k127_2153085_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 368.0
YHH1_k127_2153085_5 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 316.0
YHH1_k127_2153085_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 306.0
YHH1_k127_2153085_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 295.0
YHH1_k127_2153085_8 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003039 269.0
YHH1_k127_2153085_9 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000002974 213.0
YHH1_k127_217673_0 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 468.0
YHH1_k127_217673_1 Involved in cell shape control K22222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 457.0
YHH1_k127_217673_10 Bacterial transferase hexapeptide repeat protein - - - 0.0000000000000000000000000000000000000000101 158.0
YHH1_k127_217673_11 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000104 148.0
YHH1_k127_217673_12 Histidine kinase - - - 0.00000000000000000000000003887 129.0
YHH1_k127_217673_2 CotH kinase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 385.0
YHH1_k127_217673_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 408.0
YHH1_k127_217673_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 365.0
YHH1_k127_217673_5 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000002766 218.0
YHH1_k127_217673_6 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000829 209.0
YHH1_k127_217673_7 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000005711 206.0
YHH1_k127_217673_8 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000007834 179.0
YHH1_k127_217673_9 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000001991 164.0
YHH1_k127_2394443_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 6.775e-287 905.0
YHH1_k127_2394443_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.074e-268 835.0
YHH1_k127_2394443_10 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 500.0
YHH1_k127_2394443_11 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 491.0
YHH1_k127_2394443_12 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 488.0
YHH1_k127_2394443_13 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 443.0
YHH1_k127_2394443_14 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 432.0
YHH1_k127_2394443_15 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 425.0
YHH1_k127_2394443_16 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 425.0
YHH1_k127_2394443_17 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 410.0
YHH1_k127_2394443_18 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 397.0
YHH1_k127_2394443_19 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006848 383.0
YHH1_k127_2394443_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 4.1e-263 829.0
YHH1_k127_2394443_20 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 385.0
YHH1_k127_2394443_21 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 383.0
YHH1_k127_2394443_22 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 366.0
YHH1_k127_2394443_23 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 364.0
YHH1_k127_2394443_24 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 362.0
YHH1_k127_2394443_25 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 377.0
YHH1_k127_2394443_26 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 315.0
YHH1_k127_2394443_27 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 307.0
YHH1_k127_2394443_28 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 308.0
YHH1_k127_2394443_29 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 300.0
YHH1_k127_2394443_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.19e-245 772.0
YHH1_k127_2394443_30 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 302.0
YHH1_k127_2394443_31 CO dehydrogenase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
YHH1_k127_2394443_32 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002118 280.0
YHH1_k127_2394443_33 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005715 280.0
YHH1_k127_2394443_34 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001547 259.0
YHH1_k127_2394443_35 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
YHH1_k127_2394443_36 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000002839 234.0
YHH1_k127_2394443_37 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000003616 228.0
YHH1_k127_2394443_38 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000257 221.0
YHH1_k127_2394443_39 TIGRFAM geranylgeranyl reductase family - - - 0.0000000000000000000000000000000000000000000000000000000002192 217.0
YHH1_k127_2394443_4 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 1.942e-235 753.0
YHH1_k127_2394443_40 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000004495 205.0
YHH1_k127_2394443_41 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.00000000000000000000000000000000000000000000000001148 186.0
YHH1_k127_2394443_42 isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000003655 182.0
YHH1_k127_2394443_43 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000001516 175.0
YHH1_k127_2394443_44 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000001235 170.0
YHH1_k127_2394443_45 DNA-binding protein K06933 - - 0.00000000000000000000000000000000000000000001773 166.0
YHH1_k127_2394443_46 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000002583 159.0
YHH1_k127_2394443_47 Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000001407 151.0
YHH1_k127_2394443_48 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000005303 142.0
YHH1_k127_2394443_49 nitrogen fixation - - - 0.0000000000000000000000000000000000008977 143.0
YHH1_k127_2394443_5 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 7.363e-212 671.0
YHH1_k127_2394443_50 resolvase K06400 - - 0.0000000000000000000000000000000003472 148.0
YHH1_k127_2394443_51 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000006184 129.0
YHH1_k127_2394443_52 Staphylococcal nuclease homologues - - - 0.000000000000000000000002727 110.0
YHH1_k127_2394443_53 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.000000000000000000003433 98.0
YHH1_k127_2394443_54 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000005787 86.0
YHH1_k127_2394443_55 Family of unknown function (DUF5320) - - - 0.0000000000000001803 85.0
YHH1_k127_2394443_56 4Fe-4S binding domain K03616 - - 0.0000000000000003401 80.0
YHH1_k127_2394443_57 4Fe-4S dicluster domain - - - 0.00000000002629 70.0
YHH1_k127_2394443_58 Putative regulatory protein - - - 0.0000000000466 65.0
YHH1_k127_2394443_59 Putative regulatory protein - - - 0.000000002665 61.0
YHH1_k127_2394443_6 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.676e-198 627.0
YHH1_k127_2394443_60 NYN domain - - - 0.0000004364 58.0
YHH1_k127_2394443_61 - - - - 0.000002014 57.0
YHH1_k127_2394443_63 Resolvase, N terminal domain - - - 0.000009793 48.0
YHH1_k127_2394443_64 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0001393 44.0
YHH1_k127_2394443_65 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0002881 46.0
YHH1_k127_2394443_66 - - - - 0.0003295 51.0
YHH1_k127_2394443_67 - - - - 0.0005378 48.0
YHH1_k127_2394443_7 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 613.0
YHH1_k127_2394443_8 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 583.0
YHH1_k127_2394443_9 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 499.0
YHH1_k127_240499_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 1.226e-273 844.0
YHH1_k127_240499_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 428.0
YHH1_k127_240499_10 Zincin-like metallopeptidase - - - 0.000000000000000000000728 101.0
YHH1_k127_240499_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000004872 96.0
YHH1_k127_240499_12 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000611 81.0
YHH1_k127_240499_13 Sodium/hydrogen exchanger family K03455 - - 0.00007774 45.0
YHH1_k127_240499_14 - - - - 0.0008996 43.0
YHH1_k127_240499_2 PFAM 2-nitropropane dioxygenase NPD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 374.0
YHH1_k127_240499_4 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000007357 256.0
YHH1_k127_240499_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000001799 234.0
YHH1_k127_240499_6 HicB family - - - 0.00000000000000000000000000000000000000000000001674 173.0
YHH1_k127_240499_7 phosphoglycerate mutase family K22305 - 3.1.3.3 0.000000000000000000000000000000000001545 147.0
YHH1_k127_240499_8 - - - - 0.00000000000000000000000000000000001378 148.0
YHH1_k127_240499_9 - - - - 0.00000000000000000000000000000004313 126.0
YHH1_k127_241027_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008904 276.0
YHH1_k127_241027_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000006912 229.0
YHH1_k127_241027_2 - - - - 0.00000000000000000000002946 110.0
YHH1_k127_2432705_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.858e-257 802.0
YHH1_k127_2432705_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.34e-198 629.0
YHH1_k127_2432705_10 Phospholipase_D-nuclease N-terminal - - - 0.0000000000003505 70.0
YHH1_k127_2432705_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 446.0
YHH1_k127_2432705_3 Domain of unknown function (DUF4162) K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 353.0
YHH1_k127_2432705_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 293.0
YHH1_k127_2432705_5 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000008691 243.0
YHH1_k127_2432705_6 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000006276 197.0
YHH1_k127_2432705_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000004389 188.0
YHH1_k127_2432705_8 Domain of unknown function (DUF370) K09777 - - 0.00000000000000000000000002467 111.0
YHH1_k127_2432705_9 Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000001038 108.0
YHH1_k127_280622_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.985e-238 753.0
YHH1_k127_280622_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003033 279.0
YHH1_k127_280622_2 alpha-L-rhamnosidase - - - 0.00000000000000000000000000001693 129.0
YHH1_k127_293740_0 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 401.0
YHH1_k127_293740_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001399 240.0
YHH1_k127_293740_2 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000001224 107.0
YHH1_k127_2985330_0 PFAM Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 310.0
YHH1_k127_3282127_0 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 614.0
YHH1_k127_3282127_1 cellulase activity - - - 0.000000000000000001981 100.0
YHH1_k127_3368780_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 394.0
YHH1_k127_3368780_1 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 0.000000000000000000005728 97.0
YHH1_k127_339778_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 304.0
YHH1_k127_339778_1 regulation of RNA biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003979 280.0
YHH1_k127_339778_10 Endonuclease related to archaeal Holliday junction resolvase - - - 0.0007743 49.0
YHH1_k127_339778_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000004029 178.0
YHH1_k127_339778_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000007005 172.0
YHH1_k127_339778_4 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000634 155.0
YHH1_k127_339778_5 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000004084 101.0
YHH1_k127_339778_6 Methyltransferase domain - - - 0.000000001113 70.0
YHH1_k127_339778_7 PFAM nuclease (SNase domain protein) K01174 - 3.1.31.1 0.0000001856 60.0
YHH1_k127_339778_8 - - - - 0.000001029 61.0
YHH1_k127_339778_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000001497 53.0
YHH1_k127_3426874_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1518.0
YHH1_k127_3426874_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1278.0
YHH1_k127_3426874_10 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 423.0
YHH1_k127_3426874_11 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 401.0
YHH1_k127_3426874_12 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 370.0
YHH1_k127_3426874_13 ATPase activity K02010,K02017,K02019,K02049,K02068,K02071,K06857,K10112 - 3.6.3.29,3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 364.0
YHH1_k127_3426874_14 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 344.0
YHH1_k127_3426874_15 Metal-dependent hydrolase, beta-lactamase superfamily II K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 319.0
YHH1_k127_3426874_16 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 319.0
YHH1_k127_3426874_17 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 306.0
YHH1_k127_3426874_18 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002155 283.0
YHH1_k127_3426874_19 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001324 247.0
YHH1_k127_3426874_2 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 584.0
YHH1_k127_3426874_20 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000002435 235.0
YHH1_k127_3426874_21 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000003384 235.0
YHH1_k127_3426874_22 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000009157 218.0
YHH1_k127_3426874_23 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000006264 218.0
YHH1_k127_3426874_24 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000006856 208.0
YHH1_k127_3426874_25 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000001522 203.0
YHH1_k127_3426874_26 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000003658 187.0
YHH1_k127_3426874_27 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000009474 187.0
YHH1_k127_3426874_28 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000001132 183.0
YHH1_k127_3426874_29 - K10716 - - 0.000000000000000000000000000000000000000001059 164.0
YHH1_k127_3426874_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 576.0
YHH1_k127_3426874_30 Universal stress protein family - - - 0.0000000000000000000000000000000000000002157 153.0
YHH1_k127_3426874_31 Flavodoxin - - - 0.00000000000000000000000000000006598 129.0
YHH1_k127_3426874_32 cyclic nucleotide binding K10914 - - 0.000000000000001929 82.0
YHH1_k127_3426874_33 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.000000000004093 72.0
YHH1_k127_3426874_34 - - - - 0.00000000001186 75.0
YHH1_k127_3426874_35 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000003087 70.0
YHH1_k127_3426874_36 Cyclic nucleotide-monophosphate binding domain - - - 0.00000001689 62.0
YHH1_k127_3426874_37 - - - - 0.00007976 50.0
YHH1_k127_3426874_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 496.0
YHH1_k127_3426874_5 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 496.0
YHH1_k127_3426874_6 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 482.0
YHH1_k127_3426874_7 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 457.0
YHH1_k127_3426874_8 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 442.0
YHH1_k127_3426874_9 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 418.0
YHH1_k127_3700678_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 584.0
YHH1_k127_3700678_1 cellulase activity - - - 0.000000000000000000003473 103.0
YHH1_k127_3700678_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000003774 89.0
YHH1_k127_3726808_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 400.0
YHH1_k127_3726808_1 Deoxyhypusine synthase K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 336.0
YHH1_k127_3726808_10 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000002866 109.0
YHH1_k127_3726808_11 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000004293 99.0
YHH1_k127_3726808_12 Domain of unknown function (DUF333) K09712 - - 0.00000000000000000002028 106.0
YHH1_k127_3726808_13 - - - - 0.00000000000000002792 85.0
YHH1_k127_3726808_14 recombinase activity - - - 0.000002807 51.0
YHH1_k127_3726808_2 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 298.0
YHH1_k127_3726808_3 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005358 286.0
YHH1_k127_3726808_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003884 237.0
YHH1_k127_3726808_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000001293 211.0
YHH1_k127_3726808_6 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000007913 214.0
YHH1_k127_3726808_7 Domain of unknown function (DUF3883) - - - 0.00000000000000000000000000000000000000000000541 187.0
YHH1_k127_3726808_8 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000002121 142.0
YHH1_k127_3726808_9 Papain family cysteine protease K01365,K01406,K14475 - 3.4.22.15,3.4.24.40 0.0000000000000000000000000000000007107 148.0
YHH1_k127_3745512_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1567.0
YHH1_k127_3745512_1 Telomere recombination K04656 - - 2.415e-248 783.0
YHH1_k127_3745512_10 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000011 163.0
YHH1_k127_3745512_11 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000002529 128.0
YHH1_k127_3745512_12 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000002912 126.0
YHH1_k127_3745512_13 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000000003795 111.0
YHH1_k127_3745512_14 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000001265 106.0
YHH1_k127_3745512_15 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000009917 90.0
YHH1_k127_3745512_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436,K14126 - 1.12.1.2,1.8.98.5 9.727e-209 661.0
YHH1_k127_3745512_3 Pyridine nucleotide-disulphide oxidoreductase - - - 7.129e-194 622.0
YHH1_k127_3745512_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 442.0
YHH1_k127_3745512_5 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 309.0
YHH1_k127_3745512_6 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 305.0
YHH1_k127_3745512_7 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 292.0
YHH1_k127_3745512_8 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002393 244.0
YHH1_k127_3745512_9 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000001066 182.0
YHH1_k127_3770146_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.36e-246 771.0
YHH1_k127_3770146_1 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000001653 271.0
YHH1_k127_3770146_10 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000134 44.0
YHH1_k127_3770146_2 hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008092 268.0
YHH1_k127_3770146_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005193 259.0
YHH1_k127_3770146_4 Transcriptional regulator K07668 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000007135 224.0
YHH1_k127_3770146_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000006402 211.0
YHH1_k127_3770146_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000005467 200.0
YHH1_k127_3770146_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000002361 194.0
YHH1_k127_3770146_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000002441 146.0
YHH1_k127_3770146_9 methyltransferase K16868 - 2.1.1.265 0.0000001167 61.0
YHH1_k127_3842878_0 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 410.0
YHH1_k127_3842878_1 antibiotic catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 414.0
YHH1_k127_3842878_10 Rhomboid family - - - 0.00000000000000000000000000000000000000000001033 169.0
YHH1_k127_3842878_11 - - - - 0.0000000000000000000000000000000000000000003122 179.0
YHH1_k127_3842878_12 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000003606 164.0
YHH1_k127_3842878_13 PFAM B12 binding domain - - - 0.0000000000000000000000000000000000001126 150.0
YHH1_k127_3842878_14 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000000002042 137.0
YHH1_k127_3842878_15 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000001273 129.0
YHH1_k127_3842878_16 - - - - 0.000000000000000000006835 94.0
YHH1_k127_3842878_17 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000002779 93.0
YHH1_k127_3842878_18 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.00000000000000005009 87.0
YHH1_k127_3842878_19 Domain of unknown function (DUF2341) - - - 0.000000000009012 77.0
YHH1_k127_3842878_2 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 374.0
YHH1_k127_3842878_20 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000023 69.0
YHH1_k127_3842878_22 Di-glucose binding within endoplasmic reticulum - - - 0.0000008506 60.0
YHH1_k127_3842878_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000006141 232.0
YHH1_k127_3842878_4 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001234 255.0
YHH1_k127_3842878_5 PFAM glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000004217 231.0
YHH1_k127_3842878_6 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000001255 221.0
YHH1_k127_3842878_7 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000172 207.0
YHH1_k127_3842878_8 IMP dehydrogenase / GMP reductase domain K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000002644 199.0
YHH1_k127_3842878_9 KR domain - - - 0.000000000000000000000000000000000000000000000000333 189.0
YHH1_k127_3961201_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1190.0
YHH1_k127_3961201_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1171.0
YHH1_k127_3961201_10 PFAM glycosyl transferase group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 345.0
YHH1_k127_3961201_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 331.0
YHH1_k127_3961201_12 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 330.0
YHH1_k127_3961201_13 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 314.0
YHH1_k127_3961201_14 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 308.0
YHH1_k127_3961201_15 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 312.0
YHH1_k127_3961201_16 cobalt ion transport K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005308 273.0
YHH1_k127_3961201_17 Cobalt ABC transporter, permease protein CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006545 247.0
YHH1_k127_3961201_18 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000002735 239.0
YHH1_k127_3961201_19 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000003373 221.0
YHH1_k127_3961201_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 4.476e-320 1007.0
YHH1_k127_3961201_20 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.0000000000000000000000000000000000000000000000000000000000003664 220.0
YHH1_k127_3961201_21 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000002811 204.0
YHH1_k127_3961201_22 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000009523 196.0
YHH1_k127_3961201_23 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000001373 175.0
YHH1_k127_3961201_24 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.000000000000000000000000000000000000000000003867 173.0
YHH1_k127_3961201_25 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000009471 173.0
YHH1_k127_3961201_26 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000001017 178.0
YHH1_k127_3961201_27 PFAM Nickel transport complex, NikM subunit, transmembrane K16915 - - 0.00000000000000000000000000000000000000000001108 166.0
YHH1_k127_3961201_28 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000004272 152.0
YHH1_k127_3961201_29 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000006487 156.0
YHH1_k127_3961201_3 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 5.837e-313 966.0
YHH1_k127_3961201_30 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000002094 153.0
YHH1_k127_3961201_31 Acetyltransferase (GNAT) domain K00657 - 2.3.1.57 0.00000000000000000000000000000000593 140.0
YHH1_k127_3961201_32 Toxic component of a toxin-antitoxin (TA) module K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.0000000000000000000000000000001959 125.0
YHH1_k127_3961201_33 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000001194 115.0
YHH1_k127_3961201_34 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000001038 115.0
YHH1_k127_3961201_35 dehydratase - - - 0.00000000000000000000003226 105.0
YHH1_k127_3961201_36 - - - - 0.0000000000000107 79.0
YHH1_k127_3961201_37 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000166 78.0
YHH1_k127_3961201_38 S-layer protein - - - 0.000000001051 70.0
YHH1_k127_3961201_39 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000865 63.0
YHH1_k127_3961201_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 482.0
YHH1_k127_3961201_40 Zn-ribbon protein, possibly nucleic acid-binding K07164 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00003781 51.0
YHH1_k127_3961201_41 exo-alpha-(2->6)-sialidase activity - - - 0.0002219 54.0
YHH1_k127_3961201_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 469.0
YHH1_k127_3961201_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 406.0
YHH1_k127_3961201_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 372.0
YHH1_k127_3961201_8 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 362.0
YHH1_k127_3961201_9 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 352.0
YHH1_k127_4160264_0 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 535.0
YHH1_k127_4160264_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 475.0
YHH1_k127_4160264_2 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000002063 138.0
YHH1_k127_4160264_3 Sigma-70 region 2 K03088 - - 0.00000000000000000000000003453 114.0
YHH1_k127_4160264_5 antisigma factor binding K03090,K04749,K06378 - - 0.000002842 56.0
YHH1_k127_4399538_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.292e-294 914.0
YHH1_k127_4399538_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 560.0
YHH1_k127_4399538_2 catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 554.0
YHH1_k127_4606420_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.911e-228 727.0
YHH1_k127_4606420_1 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 519.0
YHH1_k127_4606420_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000205 213.0
YHH1_k127_4606420_11 - - - - 0.0000000000000000000000000000000000000000000000000938 177.0
YHH1_k127_4606420_12 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000000000000000000001492 145.0
YHH1_k127_4606420_13 the current gene model (or a revised gene model) may contain one or more premature stops and or frameshifts - - - 0.00000000000000000000000003942 109.0
YHH1_k127_4606420_14 - - - - 0.0000000000009899 68.0
YHH1_k127_4606420_15 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000134 71.0
YHH1_k127_4606420_16 - - - - 0.00000000001564 65.0
YHH1_k127_4606420_17 - - - - 0.00000000002602 65.0
YHH1_k127_4606420_18 Unextendable partial coding region - - - 0.0000000001013 64.0
YHH1_k127_4606420_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000002278 55.0
YHH1_k127_4606420_2 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 428.0
YHH1_k127_4606420_21 COG NOG14600 non supervised orthologous group - - - 0.0000005113 51.0
YHH1_k127_4606420_22 COG NOG38524 non supervised orthologous group - - - 0.00002569 47.0
YHH1_k127_4606420_24 Rubrerythrin - - - 0.0002336 46.0
YHH1_k127_4606420_25 - - - - 0.0002543 44.0
YHH1_k127_4606420_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 427.0
YHH1_k127_4606420_4 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 417.0
YHH1_k127_4606420_5 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 372.0
YHH1_k127_4606420_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 362.0
YHH1_k127_4606420_7 PFAM Radical SAM domain protein K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 346.0
YHH1_k127_4606420_8 Leucine-rich repeat K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003234 261.0
YHH1_k127_4606420_9 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000002627 237.0
YHH1_k127_4749623_0 Lipase (class 3) - - - 0.00000000000000008687 88.0
YHH1_k127_4749623_1 hydrolase (metallo-beta-lactamase superfamily) K02238 - - 0.0000008957 58.0
YHH1_k127_4795069_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 456.0
YHH1_k127_4795069_1 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 442.0
YHH1_k127_4795069_10 NIL domain - - - 0.00000000001693 70.0
YHH1_k127_4795069_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 425.0
YHH1_k127_4795069_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 421.0
YHH1_k127_4795069_4 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 342.0
YHH1_k127_4795069_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000195 219.0
YHH1_k127_4795069_6 UbiA prenyltransferase family K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000016 170.0
YHH1_k127_4795069_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000004226 118.0
YHH1_k127_4795069_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000003523 87.0
YHH1_k127_4795069_9 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000001094 68.0
YHH1_k127_4858391_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.65e-317 1005.0
YHH1_k127_4858391_1 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 553.0
YHH1_k127_4858391_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 364.0
YHH1_k127_4858391_11 Transketolase, central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 357.0
YHH1_k127_4858391_12 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 302.0
YHH1_k127_4858391_13 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003304 281.0
YHH1_k127_4858391_14 PFAM GTP cyclohydrolase I Nitrile oxidoreductase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000001279 250.0
YHH1_k127_4858391_15 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000002427 243.0
YHH1_k127_4858391_16 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003698 242.0
YHH1_k127_4858391_18 GTP binding - - - 0.00000000000000000000000000000000000000000000000000000000001737 220.0
YHH1_k127_4858391_19 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000007544 189.0
YHH1_k127_4858391_2 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 540.0
YHH1_k127_4858391_20 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000457 199.0
YHH1_k127_4858391_22 FMN binding - - - 0.000000000000000000000000000000000000000000000000384 181.0
YHH1_k127_4858391_23 competence protein - - - 0.000000000000000000000000000000000000000000000004377 180.0
YHH1_k127_4858391_24 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000000195 148.0
YHH1_k127_4858391_25 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000001093 129.0
YHH1_k127_4858391_26 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000001927 133.0
YHH1_k127_4858391_27 COG0840 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000198 137.0
YHH1_k127_4858391_28 - - - - 0.0000000000000000000000000003004 115.0
YHH1_k127_4858391_29 - - - - 0.0000000000000000000000000003386 116.0
YHH1_k127_4858391_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 497.0
YHH1_k127_4858391_30 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000001891 114.0
YHH1_k127_4858391_31 - - - - 0.0000000000000000000001546 101.0
YHH1_k127_4858391_32 NifU-like domain - - - 0.0000000000000000000001753 99.0
YHH1_k127_4858391_33 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000002788 90.0
YHH1_k127_4858391_34 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000003712 83.0
YHH1_k127_4858391_35 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000006317 83.0
YHH1_k127_4858391_36 - - - - 0.000000000000001178 76.0
YHH1_k127_4858391_37 Periplasmic binding protein K02016 - - 0.0002753 53.0
YHH1_k127_4858391_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 471.0
YHH1_k127_4858391_5 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 467.0
YHH1_k127_4858391_6 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 395.0
YHH1_k127_4858391_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
YHH1_k127_4858391_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 384.0
YHH1_k127_4858391_9 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 368.0
YHH1_k127_5116638_0 Molybdopterin oxidoreductase, Fe4S4 K00336,K05299 - 1.17.1.10,1.6.5.3 4.608e-298 943.0
YHH1_k127_5116638_1 NADH ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335,K18331 - 1.12.1.3,1.6.5.3 1.863e-260 817.0
YHH1_k127_5116638_10 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000000000000000007132 147.0
YHH1_k127_5116638_11 - - - - 0.000000000000000000000000000000003275 129.0
YHH1_k127_5116638_12 - - - - 0.00000000000000000000000000000001071 128.0
YHH1_k127_5116638_13 - - - - 0.0000000000000000000000004184 106.0
YHH1_k127_5116638_14 - - - - 0.00000000000000000000002342 101.0
YHH1_k127_5116638_15 - - - - 0.00000000000000000000003776 103.0
YHH1_k127_5116638_17 - - - - 0.00000000000000001052 84.0
YHH1_k127_5116638_18 - - - - 0.00000000000000266 79.0
YHH1_k127_5116638_19 - - - - 0.00000000000002944 73.0
YHH1_k127_5116638_2 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 581.0
YHH1_k127_5116638_20 - - - - 0.00000000001328 65.0
YHH1_k127_5116638_21 - - - - 0.00000000001978 67.0
YHH1_k127_5116638_23 cheY-homologous receiver domain - - - 0.0002028 49.0
YHH1_k127_5116638_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001679 259.0
YHH1_k127_5116638_4 Histidine kinase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000004373 234.0
YHH1_k127_5116638_5 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000004419 205.0
YHH1_k127_5116638_6 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000278 186.0
YHH1_k127_5116638_7 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000005665 174.0
YHH1_k127_5116638_8 COG NOG14600 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000004704 164.0
YHH1_k127_5116638_9 PAS domain K00974,K02485 - 2.7.7.72 0.0000000000000000000000000000000000000001921 173.0
YHH1_k127_513558_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 317.0
YHH1_k127_513558_1 Glycosyl transferases group 1 K12989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003003 256.0
YHH1_k127_513558_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000001742 246.0
YHH1_k127_513558_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000133 209.0
YHH1_k127_513558_4 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000005151 189.0
YHH1_k127_513558_5 pfam nudix K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000003426 175.0
YHH1_k127_513558_6 - - - - 0.000001146 56.0
YHH1_k127_5165559_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 561.0
YHH1_k127_5165559_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 327.0
YHH1_k127_5165559_10 - - - - 0.0002385 49.0
YHH1_k127_5165559_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 314.0
YHH1_k127_5165559_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000003701 193.0
YHH1_k127_5165559_4 FxsA cytoplasmic membrane protein K07113 - - 0.00000000000000000000000000007706 121.0
YHH1_k127_5165559_5 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000001462 106.0
YHH1_k127_5165559_6 TIGRFAM RHS repeat-associated core domain - - - 0.0000000000000002992 92.0
YHH1_k127_5165559_7 - - - - 0.00000000001369 66.0
YHH1_k127_5165559_8 Papain family cysteine protease K11751,K14647 - 3.1.3.5,3.6.1.45 0.000003773 59.0
YHH1_k127_5165559_9 peptidyl-tyrosine sulfation - - - 0.00006736 54.0
YHH1_k127_5502884_0 PFAM Integrase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 310.0
YHH1_k127_5524754_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.592e-253 802.0
YHH1_k127_5524754_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 543.0
YHH1_k127_5524754_10 IMP dehydrogenase activity - - - 0.0000000000000000000000000008126 118.0
YHH1_k127_5524754_11 - - - - 0.00000000000003213 87.0
YHH1_k127_5524754_12 PFAM periplasmic copper-binding - - - 0.00000000001429 76.0
YHH1_k127_5524754_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 479.0
YHH1_k127_5524754_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 390.0
YHH1_k127_5524754_4 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 379.0
YHH1_k127_5524754_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 303.0
YHH1_k127_5524754_6 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000005541 205.0
YHH1_k127_5524754_7 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000003631 141.0
YHH1_k127_5524754_8 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000002812 141.0
YHH1_k127_5524754_9 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.0000000000000000000000000000001372 126.0
YHH1_k127_5616082_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1647.0
YHH1_k127_5616082_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1459.0
YHH1_k127_5616082_10 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00001405 48.0
YHH1_k127_5616082_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.524e-233 739.0
YHH1_k127_5616082_3 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 560.0
YHH1_k127_5616082_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 386.0
YHH1_k127_5616082_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190,2.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 320.0
YHH1_k127_5616082_6 LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 294.0
YHH1_k127_5616082_7 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 301.0
YHH1_k127_5616082_8 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 293.0
YHH1_k127_5616082_9 Domain of unknown function - - - 0.0000000000000000000000000000000000000000000000000000005664 204.0
YHH1_k127_5731622_0 Elongation factor Tu domain 2 K06207 - - 5.488e-278 867.0
YHH1_k127_5731622_1 Hit family K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000001576 181.0
YHH1_k127_5731622_2 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000007037 182.0
YHH1_k127_5731622_3 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.000000000000000000000000000000009666 138.0
YHH1_k127_5731622_4 FAD dependent oxidoreductase K16051 - 1.3.99.5 0.00000002273 56.0
YHH1_k127_5731622_5 - - - - 0.0007745 42.0
YHH1_k127_5740120_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 380.0
YHH1_k127_5740120_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 374.0
YHH1_k127_5740120_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 315.0
YHH1_k127_5740120_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001217 254.0
YHH1_k127_5740120_4 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000004982 148.0
YHH1_k127_5740120_6 Protein of unknown function (DUF1284) K09706 - - 0.0000000000000000000000000005328 117.0
YHH1_k127_5740120_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000005911 105.0
YHH1_k127_5740120_8 - - - - 0.000000000000000006451 93.0
YHH1_k127_5740120_9 PQ loop repeat K15383 - - 0.0000000002363 68.0
YHH1_k127_5824492_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 332.0
YHH1_k127_5824492_1 acyl-CoA dehydrogenase activity K04117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 298.0
YHH1_k127_5824492_10 - - - - 0.00000003897 62.0
YHH1_k127_5824492_11 - - - - 0.0000005857 58.0
YHH1_k127_5824492_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002688 278.0
YHH1_k127_5824492_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002895 228.0
YHH1_k127_5824492_4 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 0.000000000000000000000000000000000000000002321 162.0
YHH1_k127_5824492_5 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000001106 148.0
YHH1_k127_5824492_6 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000002096 132.0
YHH1_k127_5824492_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000001101 120.0
YHH1_k127_5824492_8 - - - - 0.00000000000000005871 88.0
YHH1_k127_5824492_9 - - - - 0.000000000313 68.0
YHH1_k127_5873915_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 8.448e-244 780.0
YHH1_k127_5873915_1 Ferrous iron transport protein B K04759 - - 2.897e-201 641.0
YHH1_k127_5873915_10 Mycolic acid cyclopropane synthetase - - - 0.0000000008183 68.0
YHH1_k127_5873915_2 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000000000000000001707 199.0
YHH1_k127_5873915_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000382 188.0
YHH1_k127_5873915_4 KR domain K07124 - - 0.0000000000000000000000000000000000000000000000001385 184.0
YHH1_k127_5873915_5 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000001224 131.0
YHH1_k127_5873915_6 Colicin V production protein K03558 - - 0.00000000000000000000000000004622 122.0
YHH1_k127_5873915_7 4Fe-4S dicluster domain - - - 0.0000000000000000000000000001238 117.0
YHH1_k127_5873915_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000109 113.0
YHH1_k127_5873915_9 FeoA K04758 - - 0.0000000000000000001167 90.0
YHH1_k127_592701_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 551.0
YHH1_k127_592701_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 474.0
YHH1_k127_592701_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008852 469.0
YHH1_k127_6017226_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1290.0
YHH1_k127_6017226_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1146.0
YHH1_k127_6017226_10 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 384.0
YHH1_k127_6017226_11 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 383.0
YHH1_k127_6017226_12 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 368.0
YHH1_k127_6017226_13 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 360.0
YHH1_k127_6017226_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 350.0
YHH1_k127_6017226_15 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 353.0
YHH1_k127_6017226_16 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001923 283.0
YHH1_k127_6017226_17 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004169 287.0
YHH1_k127_6017226_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008994 243.0
YHH1_k127_6017226_19 PFAM plasmid pRiA4b ORF-3 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001393 233.0
YHH1_k127_6017226_2 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 1.224e-304 954.0
YHH1_k127_6017226_20 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000001522 237.0
YHH1_k127_6017226_21 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000004969 235.0
YHH1_k127_6017226_22 protein histidine kinase activity K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000005428 233.0
YHH1_k127_6017226_23 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000002728 214.0
YHH1_k127_6017226_24 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000002939 216.0
YHH1_k127_6017226_25 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000001392 213.0
YHH1_k127_6017226_26 Glutaredoxin K03676,K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000002591 191.0
YHH1_k127_6017226_27 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.0000000000000000000000000000000000000000000000000005422 188.0
YHH1_k127_6017226_28 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000005991 183.0
YHH1_k127_6017226_29 ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000009887 193.0
YHH1_k127_6017226_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 545.0
YHH1_k127_6017226_30 ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000000000000000000001167 179.0
YHH1_k127_6017226_31 NYN domain - - - 0.000000000000000000000000000000000000000000009548 169.0
YHH1_k127_6017226_32 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000001814 168.0
YHH1_k127_6017226_33 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000000008912 161.0
YHH1_k127_6017226_34 - - - - 0.0000000000000000000000000000000000000000001083 167.0
YHH1_k127_6017226_35 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000001382 153.0
YHH1_k127_6017226_36 CoA binding domain K06929 - - 0.0000000000000000000000000000000000001126 148.0
YHH1_k127_6017226_37 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000002143 141.0
YHH1_k127_6017226_38 GYD domain - - - 0.000000000000000000000000000000004246 131.0
YHH1_k127_6017226_39 - - - - 0.000000000000000000000000000004425 121.0
YHH1_k127_6017226_4 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 481.0
YHH1_k127_6017226_40 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000002045 119.0
YHH1_k127_6017226_41 Thioredoxin domain - - - 0.0000000000000000000000000007182 114.0
YHH1_k127_6017226_42 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000002363 103.0
YHH1_k127_6017226_43 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0000000000000000000007248 94.0
YHH1_k127_6017226_44 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000001116 96.0
YHH1_k127_6017226_45 Probable zinc-ribbon domain - - - 0.000000000000000015 85.0
YHH1_k127_6017226_46 - - - - 0.0000000000000001138 85.0
YHH1_k127_6017226_47 - - - - 0.000000000000001999 76.0
YHH1_k127_6017226_48 formate dehydrogenase K00127 - - 0.00000000000008449 81.0
YHH1_k127_6017226_49 redox-active disulfide protein 2 - - - 0.0000000000006234 72.0
YHH1_k127_6017226_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 460.0
YHH1_k127_6017226_50 Belongs to the glycosyl hydrolase family 6 K21104 - 3.1.1.101 0.000000000006492 77.0
YHH1_k127_6017226_51 PFAM MarR family - - - 0.0000000001177 70.0
YHH1_k127_6017226_52 recombinase activity - - - 0.000000003417 59.0
YHH1_k127_6017226_53 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K09951 - - 0.000000009564 56.0
YHH1_k127_6017226_54 - - - - 0.00000001197 58.0
YHH1_k127_6017226_55 sulphite reductase 4Fe-4S - - - 0.0000004751 54.0
YHH1_k127_6017226_57 Recombinase zinc beta ribbon domain - - - 0.000006783 49.0
YHH1_k127_6017226_58 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000007199 51.0
YHH1_k127_6017226_59 fumarate hydratase activity - - - 0.000007901 55.0
YHH1_k127_6017226_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 437.0
YHH1_k127_6017226_60 - - - - 0.00002678 49.0
YHH1_k127_6017226_61 transcriptional regulator - - - 0.00002712 53.0
YHH1_k127_6017226_62 domain protein - - - 0.0006451 50.0
YHH1_k127_6017226_63 PFAM AIR synthase related protein - - - 0.0008264 43.0
YHH1_k127_6017226_64 Chaperone protein dnaJ 1 K03686 - - 0.0009906 45.0
YHH1_k127_6017226_7 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 411.0
YHH1_k127_6017226_8 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 422.0
YHH1_k127_6017226_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 391.0
YHH1_k127_6358747_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.229e-221 708.0
YHH1_k127_6358747_1 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 580.0
YHH1_k127_6358747_2 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 433.0
YHH1_k127_6358747_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 315.0
YHH1_k127_6358747_4 ORF6N domain - - - 0.0000000000000000000000000000000000000000000000000000000001915 206.0
YHH1_k127_6358747_5 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000003141 211.0
YHH1_k127_6358747_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000008456 151.0
YHH1_k127_6358747_7 MaoC like domain - - - 0.00000000000000000000000000000004039 130.0
YHH1_k127_6358747_8 N-terminal half of MaoC dehydratase - - - 0.000000000000000000003441 100.0
YHH1_k127_6358747_9 cellulase activity K18197 - 4.2.2.23 0.000004562 58.0
YHH1_k127_6485768_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 316.0
YHH1_k127_6485768_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611,K07057 - 2.5.1.128,2.5.1.16,4.1.1.50 0.00000000000000000000000000000000002257 138.0
YHH1_k127_6485768_2 PFAM Protein-tyrosine phosphatase, low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.00000000000000000000000000005574 121.0
YHH1_k127_6485768_3 PFAM YcfA-like protein - - - 0.000000000000000000000001069 103.0
YHH1_k127_6485768_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000005793 91.0
YHH1_k127_6485768_5 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000006596 87.0
YHH1_k127_6485768_6 ORF6N domain - - - 0.000000001274 60.0
YHH1_k127_6485768_7 Belongs to the ompA family K20276 - - 0.000005841 60.0
YHH1_k127_6735900_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.495e-216 679.0
YHH1_k127_6735900_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002852 285.0
YHH1_k127_6735900_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000005137 107.0
YHH1_k127_6735900_3 Trypsin-like serine protease K01337 - 3.4.21.50 0.000000000000000000007659 109.0
YHH1_k127_6969223_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 562.0
YHH1_k127_6969223_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 395.0
YHH1_k127_6969223_10 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000001663 94.0
YHH1_k127_6969223_12 PFAM ParB domain protein nuclease K03497 - - 0.00000278 58.0
YHH1_k127_6969223_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 350.0
YHH1_k127_6969223_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003554 273.0
YHH1_k127_6969223_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
YHH1_k127_6969223_5 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000001033 233.0
YHH1_k127_6969223_6 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000568 228.0
YHH1_k127_6969223_7 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.0000000000000000000000000000000000000892 149.0
YHH1_k127_6969223_8 - - - - 0.00000000000000000000000000003396 119.0
YHH1_k127_6969223_9 peptidase U32 - - - 0.00000000000000000000000001873 110.0
YHH1_k127_7076067_0 Methylamine utilisation protein MauE - - - 0.0000001307 61.0
YHH1_k127_7076067_1 - - - - 0.000003538 57.0
YHH1_k127_7076067_2 Transmembrane and TPR repeat-containing protein - - - 0.00006017 53.0
YHH1_k127_7106201_0 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000000001428 245.0
YHH1_k127_7106201_1 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000003719 237.0
YHH1_k127_7106201_2 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000001367 108.0
YHH1_k127_7116067_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 2.031e-252 791.0
YHH1_k127_7116067_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 486.0
YHH1_k127_7116067_10 Zn-dependent hydrolases including glyoxylases-like protein - - - 0.00000000000000000000000000000000000000000000000001867 192.0
YHH1_k127_7116067_11 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000003188 169.0
YHH1_k127_7116067_12 PFAM peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000000001394 163.0
YHH1_k127_7116067_13 4-oxalocrotonate tautomerase - - - 0.00000000000295 69.0
YHH1_k127_7116067_15 SNARE associated Golgi protein - - - 0.0000001907 63.0
YHH1_k127_7116067_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 303.0
YHH1_k127_7116067_3 Poly A polymerase head domain K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000003886 261.0
YHH1_k127_7116067_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000765 257.0
YHH1_k127_7116067_5 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001109 243.0
YHH1_k127_7116067_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000002668 243.0
YHH1_k127_7116067_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005259 237.0
YHH1_k127_7116067_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000009083 238.0
YHH1_k127_7116067_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000003511 209.0
YHH1_k127_7243890_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 540.0
YHH1_k127_7243890_1 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 488.0
YHH1_k127_7243890_10 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000007262 158.0
YHH1_k127_7243890_11 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000005149 151.0
YHH1_k127_7243890_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000006683 149.0
YHH1_k127_7243890_13 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000005791 139.0
YHH1_k127_7243890_14 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000002622 102.0
YHH1_k127_7243890_15 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000005656 102.0
YHH1_k127_7243890_16 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000006538 79.0
YHH1_k127_7243890_17 PFAM PKD domain containing protein - - - 0.000000000001345 81.0
YHH1_k127_7243890_18 Mucin-2 protein WxxW repeating region K03900,K10955,K13908,K21125 GO:0001894,GO:0002064,GO:0003008,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0006915,GO:0007586,GO:0008150,GO:0008219,GO:0008285,GO:0009888,GO:0009987,GO:0010669,GO:0010941,GO:0010942,GO:0012501,GO:0022600,GO:0030154,GO:0030277,GO:0030334,GO:0030336,GO:0030855,GO:0031012,GO:0032501,GO:0032502,GO:0032879,GO:0040012,GO:0040013,GO:0042127,GO:0042592,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0044421,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048856,GO:0048869,GO:0048871,GO:0050789,GO:0050794,GO:0051270,GO:0051271,GO:0060249,GO:0060429,GO:0065007,GO:0065008,GO:0070701,GO:0070702,GO:0070703,GO:2000145,GO:2000146 - 0.0002375 54.0
YHH1_k127_7243890_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 385.0
YHH1_k127_7243890_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 352.0
YHH1_k127_7243890_4 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 332.0
YHH1_k127_7243890_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 323.0
YHH1_k127_7243890_6 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001357 270.0
YHH1_k127_7243890_7 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007516 250.0
YHH1_k127_7243890_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006687 233.0
YHH1_k127_7243890_9 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.000000000000000000000000000000000000000000000000000000000131 212.0
YHH1_k127_7281515_0 Glycosyl hydrolase family 65, C-terminal domain - - - 1.135e-313 964.0
YHH1_k127_7328553_0 elongation factor G K02355 - - 2.882e-229 738.0
YHH1_k127_7328553_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.924e-209 661.0
YHH1_k127_7328553_10 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000007357 205.0
YHH1_k127_7328553_11 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000001509 108.0
YHH1_k127_7328553_12 ubiE/COQ5 methyltransferase family K00568 - 2.1.1.222,2.1.1.64 0.00000004411 63.0
YHH1_k127_7328553_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 569.0
YHH1_k127_7328553_3 FAD dependent oxidoreductase K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 569.0
YHH1_k127_7328553_4 Aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 510.0
YHH1_k127_7328553_5 TIGRFAM Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 516.0
YHH1_k127_7328553_6 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 310.0
YHH1_k127_7328553_7 electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000171 256.0
YHH1_k127_7328553_8 Diphthamide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003542 251.0
YHH1_k127_7328553_9 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000006848 213.0
YHH1_k127_7338326_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 482.0
YHH1_k127_7338326_1 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 430.0
YHH1_k127_7338326_10 response regulator, receiver - - - 0.00000000000000000001485 109.0
YHH1_k127_7338326_11 helix_turn_helix multiple antibiotic resistance protein - - - 0.000002919 57.0
YHH1_k127_7338326_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 396.0
YHH1_k127_7338326_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 364.0
YHH1_k127_7338326_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 311.0
YHH1_k127_7338326_5 phosphorelay sensor kinase activity K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 325.0
YHH1_k127_7338326_6 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000159 224.0
YHH1_k127_7338326_7 Enoyl-CoA hydratase K07539,K18570 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.00000000000000000000000000000000000000133 158.0
YHH1_k127_7338326_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000001761 137.0
YHH1_k127_7338326_9 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000001041 108.0
YHH1_k127_7524951_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 406.0
YHH1_k127_7524951_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 410.0
YHH1_k127_7524951_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003647 260.0
YHH1_k127_7524951_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000001397 243.0
YHH1_k127_7524951_4 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 0.000000000000000001261 92.0
YHH1_k127_7584109_0 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 445.0
YHH1_k127_7584109_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
YHH1_k127_7584109_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 293.0
YHH1_k127_7584109_3 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004208 258.0
YHH1_k127_7584109_4 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000008873 139.0
YHH1_k127_7584109_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000004045 114.0
YHH1_k127_7603280_0 Elongation factor SelB, winged helix K03833 - - 1.278e-194 624.0
YHH1_k127_7603280_1 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 512.0
YHH1_k127_7603280_10 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000121 192.0
YHH1_k127_7603280_11 Protein of unknown function (DUF3343) - - - 0.0000000000000000000000000000000000000000000000000001656 190.0
YHH1_k127_7603280_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000004003 181.0
YHH1_k127_7603280_13 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000003639 175.0
YHH1_k127_7603280_14 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.0000000000000000000000000000000000000001407 158.0
YHH1_k127_7603280_15 Helix-turn-helix domain - - - 0.0000000000000000000000002441 116.0
YHH1_k127_7603280_16 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000001426 78.0
YHH1_k127_7603280_17 Belongs to the precorrin methyltransferase family K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.2.1.75 0.0000006868 51.0
YHH1_k127_7603280_2 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 467.0
YHH1_k127_7603280_3 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 440.0
YHH1_k127_7603280_4 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 397.0
YHH1_k127_7603280_5 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 397.0
YHH1_k127_7603280_6 Carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 364.0
YHH1_k127_7603280_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 311.0
YHH1_k127_7603280_8 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005189 258.0
YHH1_k127_7603280_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000005384 250.0
YHH1_k127_774887_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 554.0
YHH1_k127_774887_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 415.0
YHH1_k127_774887_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000953 256.0
YHH1_k127_774887_3 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000007495 217.0
YHH1_k127_774887_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000001902 218.0
YHH1_k127_774887_5 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000003766 142.0
YHH1_k127_774887_6 Acetyltransferase (GNAT) domain - - - 0.0000001862 54.0
YHH1_k127_7975037_0 COGs COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001228 270.0
YHH1_k127_7975037_1 Nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000000000000000002251 172.0
YHH1_k127_7975037_2 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000004699 143.0
YHH1_k127_7975037_3 methyltransferase - - - 0.0000000000000000001511 97.0
YHH1_k127_7988961_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.0 1146.0
YHH1_k127_7988961_1 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 8.669e-219 708.0
YHH1_k127_7988961_10 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001681 250.0
YHH1_k127_7988961_11 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002263 227.0
YHH1_k127_7988961_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001556 226.0
YHH1_k127_7988961_13 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
YHH1_k127_7988961_14 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000009296 218.0
YHH1_k127_7988961_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000001168 203.0
YHH1_k127_7988961_16 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000003936 187.0
YHH1_k127_7988961_17 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000003904 182.0
YHH1_k127_7988961_18 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000004961 152.0
YHH1_k127_7988961_19 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.0000000000000000000000000000005655 127.0
YHH1_k127_7988961_2 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 609.0
YHH1_k127_7988961_20 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000004573 130.0
YHH1_k127_7988961_21 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000001171 108.0
YHH1_k127_7988961_22 CO dehydrogenase/acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0000000002746 70.0
YHH1_k127_7988961_23 FecR protein - - - 0.00008682 53.0
YHH1_k127_7988961_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 542.0
YHH1_k127_7988961_4 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 465.0
YHH1_k127_7988961_5 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 331.0
YHH1_k127_7988961_6 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 318.0
YHH1_k127_7988961_7 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001425 276.0
YHH1_k127_7988961_8 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004204 263.0
YHH1_k127_7988961_9 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002129 263.0
YHH1_k127_8101741_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 448.0
YHH1_k127_8101741_1 - - - - 0.000842 46.0
YHH1_k127_8302438_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 456.0
YHH1_k127_8302438_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 396.0
YHH1_k127_8302438_2 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 361.0
YHH1_k127_8302438_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 290.0
YHH1_k127_8302438_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000004554 190.0
YHH1_k127_8302438_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000008032 155.0
YHH1_k127_8380161_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.057e-247 779.0
YHH1_k127_8380161_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.048e-219 691.0
YHH1_k127_8380161_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 562.0
YHH1_k127_8380161_3 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 501.0
YHH1_k127_8380161_4 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 347.0
YHH1_k127_8380161_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 328.0
YHH1_k127_8380161_6 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 305.0
YHH1_k127_8380161_7 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000001726 195.0
YHH1_k127_8380161_8 Pfam:N_methyl_2 K02650 - - 0.0001823 50.0
YHH1_k127_8742491_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 607.0
YHH1_k127_8742491_1 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 595.0
YHH1_k127_8742491_10 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 291.0
YHH1_k127_8742491_11 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001623 271.0
YHH1_k127_8742491_12 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002088 247.0
YHH1_k127_8742491_13 PFAM Silent information regulator protein Sir2 K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000008265 242.0
YHH1_k127_8742491_14 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000003026 201.0
YHH1_k127_8742491_15 - - - - 0.000000000000000000000000000000000000000000000000002556 185.0
YHH1_k127_8742491_16 NIL - - - 0.000000000000000000000000000000000000000000000000002666 184.0
YHH1_k127_8742491_17 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000002274 182.0
YHH1_k127_8742491_18 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000001019 165.0
YHH1_k127_8742491_19 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000003584 130.0
YHH1_k127_8742491_2 FAD dependent oxidoreductase K16051 - 1.3.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 496.0
YHH1_k127_8742491_20 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000001396 126.0
YHH1_k127_8742491_21 - - - - 0.000001973 53.0
YHH1_k127_8742491_3 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 473.0
YHH1_k127_8742491_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 423.0
YHH1_k127_8742491_5 Oxidoreductase, FAD FMN-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 409.0
YHH1_k127_8742491_6 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 416.0
YHH1_k127_8742491_7 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 380.0
YHH1_k127_8742491_8 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 302.0
YHH1_k127_8742491_9 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 292.0
YHH1_k127_8813383_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 339.0
YHH1_k127_8813383_1 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000002404 235.0
YHH1_k127_8813383_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000003464 156.0
YHH1_k127_8813383_3 Ftsk_gamma K03466 - - 0.0000107 56.0
YHH1_k127_8868053_0 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000003198 210.0
YHH1_k127_8868053_1 Domain of unknown function (DUF2341) - - - 0.00000000000000000000000000000000022 154.0
YHH1_k127_8868053_2 Group II intron, maturase-specific domain K00986 - 2.7.7.49 0.00001409 51.0
YHH1_k127_9260342_0 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001393 228.0
YHH1_k127_9260342_1 Fibronectin type 3 domain K20276 - - 0.00000000000000000000000009113 126.0
YHH1_k127_9260342_2 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000003296 72.0
YHH1_k127_9692117_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 9.517e-281 877.0
YHH1_k127_9692117_1 Conserved carboxylase domain K01960 - 6.4.1.1 9.677e-249 782.0
YHH1_k127_9692117_10 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 351.0
YHH1_k127_9692117_11 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 335.0
YHH1_k127_9692117_12 Methylmalonyl-CoA mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 331.0
YHH1_k127_9692117_13 PFAM Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 295.0
YHH1_k127_9692117_14 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003144 278.0
YHH1_k127_9692117_15 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004763 264.0
YHH1_k127_9692117_16 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000002951 264.0
YHH1_k127_9692117_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000001288 244.0
YHH1_k127_9692117_18 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001047 251.0
YHH1_k127_9692117_19 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000003784 247.0
YHH1_k127_9692117_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 2.916e-234 736.0
YHH1_k127_9692117_20 nitronate monooxygenase activity K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001375 241.0
YHH1_k127_9692117_21 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000399 213.0
YHH1_k127_9692117_22 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000455 205.0
YHH1_k127_9692117_23 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.0000000000000000000000000000000000000000000005256 178.0
YHH1_k127_9692117_24 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000006665 143.0
YHH1_k127_9692117_25 B12- binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000001919 142.0
YHH1_k127_9692117_26 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000001421 133.0
YHH1_k127_9692117_27 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000002646 137.0
YHH1_k127_9692117_28 ATP-binding region, ATPase domain protein K03413,K07662,K07667 - - 0.000000000000000000000000000000004671 132.0
YHH1_k127_9692117_29 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000000000000000001092 119.0
YHH1_k127_9692117_3 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 7.114e-226 709.0
YHH1_k127_9692117_30 Trm112p-like protein - - - 0.0000000000000000000009754 95.0
YHH1_k127_9692117_31 AIPR protein - - - 0.00000000000000000007556 104.0
YHH1_k127_9692117_32 Putative regulatory protein - - - 0.000000000000003557 79.0
YHH1_k127_9692117_33 DUF167 K09131 - - 0.000000000005334 71.0
YHH1_k127_9692117_34 Methyltransferase - - - 0.000000000008777 75.0
YHH1_k127_9692117_4 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 2.95e-202 638.0
YHH1_k127_9692117_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 582.0
YHH1_k127_9692117_6 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 482.0
YHH1_k127_9692117_7 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 463.0
YHH1_k127_9692117_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 423.0
YHH1_k127_9692117_9 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 381.0
YHH1_k127_9709284_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 479.0
YHH1_k127_9709284_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 313.0
YHH1_k127_9709284_2 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000000000001121 149.0
YHH1_k127_9709284_3 - - - - 0.00000002512 63.0
YHH1_k127_9715990_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 1.673e-196 625.0
YHH1_k127_9715990_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 484.0
YHH1_k127_9715990_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 466.0
YHH1_k127_9715990_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 294.0
YHH1_k127_9715990_4 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001165 247.0
YHH1_k127_9715990_5 HicB family - - - 0.000000000000000000000000006229 114.0
YHH1_k127_9756467_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009253 385.0
YHH1_k127_9756467_1 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000001153 237.0
YHH1_k127_9841157_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 8.421e-259 848.0
YHH1_k127_9841157_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 610.0
YHH1_k127_9841157_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000036 219.0
YHH1_k127_9841157_11 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000183 163.0
YHH1_k127_9841157_12 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000003042 127.0
YHH1_k127_9841157_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.000000000000000000000000001931 120.0
YHH1_k127_9841157_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000003965 72.0
YHH1_k127_9841157_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 484.0
YHH1_k127_9841157_3 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 470.0
YHH1_k127_9841157_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 371.0
YHH1_k127_9841157_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 331.0
YHH1_k127_9841157_6 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 301.0
YHH1_k127_9841157_7 Acyl-CoA dehydrogenase, middle domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 296.0
YHH1_k127_9841157_8 Sodium/calcium exchanger protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002483 242.0
YHH1_k127_9841157_9 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003817 230.0
YHH1_k127_9877332_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.09e-247 775.0
YHH1_k127_9877332_1 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000004284 171.0
YHH1_k127_9877332_2 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.00000000000000000000000000000000000001723 147.0