Overview

ID MAG04513
Name YHH1_bin.99
Sample SMP0121
Taxonomy
Kingdom Bacteria
Phylum Patescibacteriota
Class Microgenomatia
Order UBA10105
Family UBA927
Genus
Species
Assembly information
Completeness (%) 62.77
Contamination (%) 2.4
GC content (%) 49.0
N50 (bp) 6,342
Genome size (bp) 1,070,731

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes906

Gene name Description KEGG GOs EC E-value Score Sequence
YHH1_k127_10043855_0 amine dehydrogenase activity - - - 0.000006854 57.0
YHH1_k127_10053948_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000233 268.0
YHH1_k127_10053948_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000004677 99.0
YHH1_k127_1007560_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000001558 145.0
YHH1_k127_1007560_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000214 54.0
YHH1_k127_10098046_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 508.0
YHH1_k127_10098046_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000027 187.0
YHH1_k127_10098046_2 tRNA rRNA methyltransferase K03218,K03437 - 2.1.1.185 0.0000000000000000000000000000003145 129.0
YHH1_k127_10098046_3 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000000000003121 101.0
YHH1_k127_10098046_4 NUDIX domain - - - 0.00000000000000000009164 103.0
YHH1_k127_10287948_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 312.0
YHH1_k127_10287948_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000001472 130.0
YHH1_k127_10287948_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000001775 93.0
YHH1_k127_10331605_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002175 60.0
YHH1_k127_10331605_1 oligosaccharyl transferase activity - - - 0.00001378 57.0
YHH1_k127_10367569_0 thiolester hydrolase activity - - - 0.000000000000000000000000003866 124.0
YHH1_k127_10391462_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 480.0
YHH1_k127_10391462_1 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 355.0
YHH1_k127_10391462_2 Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000000000000000000009321 214.0
YHH1_k127_10391462_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000003623 210.0
YHH1_k127_10391462_4 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000004043 186.0
YHH1_k127_10391462_5 Methyltransferase domain - - - 0.00000000000000000000000000000000000006613 152.0
YHH1_k127_10402414_0 ATPase, AAA superfamily K07133 - - 0.00000000000000000001465 100.0
YHH1_k127_10402414_1 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000004695 67.0
YHH1_k127_1046138_0 Two component regulator propeller - - - 3.747e-198 655.0
YHH1_k127_10507064_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 473.0
YHH1_k127_10507064_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003543 280.0
YHH1_k127_10507064_2 coenzyme F420-1:gamma-L-glutamate ligase activity K12234,K22099 - 6.3.2.12,6.3.2.17,6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000002182 231.0
YHH1_k127_10507064_3 Fic/DOC family - - - 0.0000000000000000000000000000000000000000001375 172.0
YHH1_k127_10507064_4 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000003944 151.0
YHH1_k127_10507064_5 Major Facilitator - - - 0.0000000000000000000005891 109.0
YHH1_k127_10507064_6 Pfam:DUF2233 - - - 0.0000000592 63.0
YHH1_k127_10507064_7 - - - - 0.00000008907 55.0
YHH1_k127_10699399_0 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000002905 145.0
YHH1_k127_10699399_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000002621 128.0
YHH1_k127_10699399_2 Transposase - - - 0.0000000000000000000000000185 117.0
YHH1_k127_10699399_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000001604 110.0
YHH1_k127_10699399_4 Fic/DOC family K07341 - - 0.000000000000000000000001728 108.0
YHH1_k127_10699399_5 GIY-YIG catalytic domain K07461 - - 0.0000000000000000001408 90.0
YHH1_k127_10699399_6 COG1910 Periplasmic molybdate-binding protein domain K07219 - - 0.0000003612 55.0
YHH1_k127_10699399_7 PIN domain - - - 0.000001146 56.0
YHH1_k127_10699399_8 SpoVT / AbrB like domain - - - 0.000002198 52.0
YHH1_k127_10699399_9 PFAM Septum formation initiator K05589 - - 0.0001226 49.0
YHH1_k127_10751346_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 440.0
YHH1_k127_10751346_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000004369 190.0
YHH1_k127_10751346_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000008862 123.0
YHH1_k127_10751346_3 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000008379 74.0
YHH1_k127_10751346_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000007226 61.0
YHH1_k127_10765430_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 8.255e-235 751.0
YHH1_k127_10765430_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 310.0
YHH1_k127_10765430_2 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000001348 125.0
YHH1_k127_10765430_3 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000009317 101.0
YHH1_k127_10765430_4 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000004807 61.0
YHH1_k127_10765430_5 domain protein K21688 GO:0005575,GO:0005576,GO:0008150,GO:0009892,GO:0009893,GO:0010468,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019222,GO:0022611,GO:0032502,GO:0040008,GO:0040009,GO:0040010,GO:0044111,GO:0044114,GO:0044115,GO:0044403,GO:0044419,GO:0045927,GO:0048518,GO:0048519,GO:0050789,GO:0051704,GO:0060255,GO:0065007,GO:0085016 - 0.0000001033 61.0
YHH1_k127_10775363_0 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 308.0
YHH1_k127_10775363_2 - - - - 0.000000001309 62.0
YHH1_k127_10775363_3 Ami_3 K01448 - 3.5.1.28 0.00002396 52.0
YHH1_k127_10797020_0 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.00000000000000009356 86.0
YHH1_k127_10797020_1 Peptidase, M23 K21471 - - 0.00000000008029 74.0
YHH1_k127_10881512_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000005593 167.0
YHH1_k127_10881512_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000005589 99.0
YHH1_k127_10881512_2 protein transport across the cell outer membrane K02457,K08084 - - 0.0000005617 58.0
YHH1_k127_10881512_3 Pfam:N_methyl_2 K02456 - - 0.0000038 56.0
YHH1_k127_10881512_4 TIGRFAM general secretion pathway protein G K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0001298 49.0
YHH1_k127_10881512_5 - - - - 0.0005593 49.0
YHH1_k127_1112558_0 D-isomer specific 2-hydroxyacid dehydrogenase K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000005104 152.0
YHH1_k127_1112558_1 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000003836 97.0
YHH1_k127_1112558_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000006826 56.0
YHH1_k127_1120194_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000001254 160.0
YHH1_k127_1120194_1 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000188 106.0
YHH1_k127_1120194_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000009223 78.0
YHH1_k127_1132545_0 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000001546 126.0
YHH1_k127_1132545_1 PFAM Glycosyl transferase, group 1 K12994 - 2.4.1.349 0.0000000000000000000000000001252 129.0
YHH1_k127_1132545_2 Glycosyl transferase family 2 K07011 - - 0.000000000000008557 84.0
YHH1_k127_1132545_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000008497 68.0
YHH1_k127_1146601_0 Glycosyl transferase, family 2 K16648 - - 0.0000001881 64.0
YHH1_k127_1167715_0 peptidyl-tyrosine sulfation - - - 0.0000000000932 70.0
YHH1_k127_1167715_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000004001 54.0
YHH1_k127_1190360_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 9.615e-233 738.0
YHH1_k127_1190360_1 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000002291 178.0
YHH1_k127_1190360_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000008097 183.0
YHH1_k127_1190360_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000009282 167.0
YHH1_k127_1234749_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 451.0
YHH1_k127_1234749_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000004644 203.0
YHH1_k127_1234749_2 Nudix hydrolase K03574 - 3.6.1.55 0.000000147 58.0
YHH1_k127_1234749_3 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.000002669 56.0
YHH1_k127_1326069_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 429.0
YHH1_k127_1326069_1 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 330.0
YHH1_k127_1326069_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000001541 238.0
YHH1_k127_1326069_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000319 235.0
YHH1_k127_1326069_4 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000004675 194.0
YHH1_k127_1326069_5 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.0000000000000000000000000000000000000000006627 169.0
YHH1_k127_1326069_6 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000007367 91.0
YHH1_k127_1326069_7 TIGRFAM methyltransferase FkbM family - - - 0.0000001106 62.0
YHH1_k127_137677_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 390.0
YHH1_k127_137677_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001043 280.0
YHH1_k127_137677_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000003643 173.0
YHH1_k127_137677_3 AI-2E family transporter K03548 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000001137 142.0
YHH1_k127_137677_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000002731 104.0
YHH1_k127_137677_5 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000004264 93.0
YHH1_k127_137677_6 Protein of unknown function (DUF4446) - - - 0.000000000000000007649 89.0
YHH1_k127_137677_7 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000001013 59.0
YHH1_k127_1402077_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.233e-265 841.0
YHH1_k127_1402077_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000002662 196.0
YHH1_k127_1432444_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001809 248.0
YHH1_k127_1432444_1 thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000002505 237.0
YHH1_k127_1432444_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000007789 203.0
YHH1_k127_1432444_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000001091 196.0
YHH1_k127_1432444_4 - - - - 0.0000000000000000000000000000000000002147 150.0
YHH1_k127_1432444_5 EamA-like transporter family - - - 0.000000000000000000000001147 115.0
YHH1_k127_1432444_6 hydrogenase, delta subunit - - - 0.000000001594 65.0
YHH1_k127_145490_0 membrane K08978 - - 0.00000000000000000000000000000000000000002704 156.0
YHH1_k127_145490_1 domain protein - - - 0.00008896 51.0
YHH1_k127_1484976_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 416.0
YHH1_k127_1484976_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000008903 168.0
YHH1_k127_1484976_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000002314 124.0
YHH1_k127_1484976_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000001495 81.0
YHH1_k127_1484976_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000002799 53.0
YHH1_k127_1593256_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000003512 237.0
YHH1_k127_1650235_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1091.0
YHH1_k127_1720727_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000003858 205.0
YHH1_k127_1720727_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000008731 129.0
YHH1_k127_1720727_2 NUDIX domain K01823 - 5.3.3.2 0.000000000000000000000001265 117.0
YHH1_k127_1748027_0 Bacterial PH domain - - - 0.000003391 56.0
YHH1_k127_1748177_0 glycogen (starch) synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002995 238.0
YHH1_k127_1748177_1 PFAM glycosyl transferase group 1 - - - 0.000000001775 61.0
YHH1_k127_180375_0 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 435.0
YHH1_k127_180375_1 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 401.0
YHH1_k127_180375_2 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000001959 166.0
YHH1_k127_180375_3 phosphoglycolate phosphatase activity - - - 0.00000000000000000000000000000001029 136.0
YHH1_k127_180375_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000002358 126.0
YHH1_k127_180375_5 oligosaccharyl transferase activity - - - 0.0000006071 62.0
YHH1_k127_180375_6 methyltransferase - - - 0.00001269 52.0
YHH1_k127_1846242_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001767 231.0
YHH1_k127_1846242_1 Glycosyl transferase family group 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000129 223.0
YHH1_k127_1846242_2 Polysaccharide biosynthesis protein K03328 - - 0.000000000000000000000000000000000000000000000000000000000001136 228.0
YHH1_k127_1846242_3 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000006696 184.0
YHH1_k127_1846242_4 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000006396 114.0
YHH1_k127_1846242_5 Psort location CytoplasmicMembrane, score - - - 0.000004082 56.0
YHH1_k127_1862048_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 327.0
YHH1_k127_1862048_1 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 305.0
YHH1_k127_1862048_2 Domain of unknown function(DUF2779) - - - 0.000000000000000000000000000000000000000000000000000002255 196.0
YHH1_k127_1862048_3 methyltransferase - - - 0.00000000000000000000000000000001102 136.0
YHH1_k127_1862048_4 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000001895 100.0
YHH1_k127_1862048_5 PFAM SNARE associated Golgi protein - - - 0.00002044 53.0
YHH1_k127_1936782_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 512.0
YHH1_k127_1936782_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000295 291.0
YHH1_k127_1936782_2 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000244 286.0
YHH1_k127_1936782_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000001136 218.0
YHH1_k127_1936782_4 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000007046 94.0
YHH1_k127_1936782_5 KH domain K06960 - - 0.0000000000000168 76.0
YHH1_k127_1936782_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000004869 70.0
YHH1_k127_1936782_7 Ribosomal L32p protein family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000005743 69.0
YHH1_k127_1986459_0 Type IV secretory pathway, VirB4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 419.0
YHH1_k127_2132713_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 295.0
YHH1_k127_2132713_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000003017 208.0
YHH1_k127_2132713_2 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000005251 192.0
YHH1_k127_2132713_3 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000235 122.0
YHH1_k127_2132713_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000008798 87.0
YHH1_k127_2132713_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001424 68.0
YHH1_k127_2132713_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000002306 65.0
YHH1_k127_2185308_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 544.0
YHH1_k127_2185308_1 Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004836 283.0
YHH1_k127_2185308_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000001254 117.0
YHH1_k127_2228183_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 419.0
YHH1_k127_2228183_1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases K00523 - 1.17.1.1 0.00000000000000000000000000004167 126.0
YHH1_k127_2228183_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000004569 72.0
YHH1_k127_2228183_3 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - - - 0.000000001135 67.0
YHH1_k127_2228183_5 - - - - 0.00007062 45.0
YHH1_k127_2438495_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.00000000000000000000000000000000001165 143.0
YHH1_k127_2438495_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000001922 130.0
YHH1_k127_2438495_2 Preprotein translocase SecG subunit K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000004807 51.0
YHH1_k127_2489570_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005125 260.0
YHH1_k127_2489570_1 COG3119 Arylsulfatase A and related enzymes K01137 - 3.1.6.14 0.000000000000000000000000000001634 141.0
YHH1_k127_2489570_2 Sulfatase K01137 - 3.1.6.14 0.0000000000000000000000001862 124.0
YHH1_k127_2489570_3 Staphylococcal nuclease homologues K01174,K07038 - 3.1.31.1 0.000000000000000009214 92.0
YHH1_k127_2489570_4 - - - - 0.000000001251 68.0
YHH1_k127_2489570_5 - - - - 0.0000004411 55.0
YHH1_k127_2579514_0 DEAD DEAH box helicase domain protein K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 310.0
YHH1_k127_2588595_0 lysyl-tRNA synthetase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
YHH1_k127_2588595_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000007319 192.0
YHH1_k127_2588595_11 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000008055 63.0
YHH1_k127_2588595_12 copper amine - - - 0.0000006502 61.0
YHH1_k127_2588595_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K12132 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.11.1,5.2.1.8 0.0000000000000000000000000000000000000000000000000001148 194.0
YHH1_k127_2588595_3 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.00000000000000000000000000000000000000000004037 169.0
YHH1_k127_2588595_4 Uncharacterized protein domain (DUF2202) - - - 0.0000000000000000000000000000003445 135.0
YHH1_k127_2588595_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000001842 109.0
YHH1_k127_2588595_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000001184 104.0
YHH1_k127_2588595_7 DUF218 domain - - - 0.00000000000001606 81.0
YHH1_k127_2588595_8 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000003322 77.0
YHH1_k127_2588595_9 peptidyl-prolyl isomerase K03769,K07533 - 5.2.1.8 0.00000000001989 73.0
YHH1_k127_2688649_0 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 383.0
YHH1_k127_2852644_0 Glycosyl transferases group 1 - - - 0.000000000000000000002275 106.0
YHH1_k127_2985997_0 Glycosyl transferase family group 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 397.0
YHH1_k127_2985997_1 Glycoside-hydrolase family GH114 - - - 0.000000000000000000000000000000000000000000000000000000000002914 216.0
YHH1_k127_2985997_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000005894 164.0
YHH1_k127_2985997_3 MgtC family K07507 - - 0.000000000000000000000000000000000000001497 151.0
YHH1_k127_2985997_4 Belongs to the UPF0251 family - - - 0.00000000000000000000004124 101.0
YHH1_k127_298682_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 2.515e-309 977.0
YHH1_k127_298682_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000415 233.0
YHH1_k127_298682_2 Putative RNA methylase family UPF0020 - - - 0.0000000000000000000000009308 115.0
YHH1_k127_298682_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000002814 93.0
YHH1_k127_3005012_0 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000007804 73.0
YHH1_k127_3005012_1 Addiction module toxin, RelE StbE family - - - 0.00000001153 59.0
YHH1_k127_3005012_2 DNA-binding helix-turn-helix protein - - - 0.000001775 51.0
YHH1_k127_3005012_3 PaaX-like protein C-terminal domain K02616 - - 0.00001818 54.0
YHH1_k127_30238_0 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000006041 187.0
YHH1_k127_30238_1 Transposase IS116 IS110 IS902 family - - - 0.00000000000000000000001252 113.0
YHH1_k127_3032176_0 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000002119 207.0
YHH1_k127_3032176_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000001252 196.0
YHH1_k127_3032176_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000001022 110.0
YHH1_k127_3032176_3 Trp repressor protein K03720 - - 0.00000000002014 68.0
YHH1_k127_3032176_4 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.0007132 48.0
YHH1_k127_3107772_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 528.0
YHH1_k127_3107772_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 458.0
YHH1_k127_3107772_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004409 274.0
YHH1_k127_3107772_3 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000755 134.0
YHH1_k127_3107772_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000006277 127.0
YHH1_k127_3107772_5 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.00000004975 63.0
YHH1_k127_316051_0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000003639 175.0
YHH1_k127_316051_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001279 178.0
YHH1_k127_316051_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000004603 51.0
YHH1_k127_3202396_0 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000004299 53.0
YHH1_k127_3222688_0 Belongs to the HMG-CoA reductase family K00021 GO:0003674,GO:0003824,GO:0004420,GO:0006629,GO:0006694,GO:0006720,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016125,GO:0016126,GO:0016491,GO:0016614,GO:0016616,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 1.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 336.0
YHH1_k127_3222688_1 Nucleotidyltransferase substrate binding protein like - - - 0.0000000000000000000000004361 108.0
YHH1_k127_3222688_2 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000002404 98.0
YHH1_k127_3222688_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000005505 70.0
YHH1_k127_3222688_4 Nucleotidyltransferase domain - - - 0.000000007226 61.0
YHH1_k127_3222688_5 - - - - 0.00001119 52.0
YHH1_k127_3222688_6 - - - - 0.00008979 50.0
YHH1_k127_3222688_7 - - - - 0.0005938 46.0
YHH1_k127_3249358_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 341.0
YHH1_k127_3249358_1 PFAM deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000007696 155.0
YHH1_k127_3289650_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006629 269.0
YHH1_k127_3289650_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000003511 229.0
YHH1_k127_3289650_10 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed K01265 - 3.4.11.18 0.000000005031 60.0
YHH1_k127_3289650_11 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.0000001254 61.0
YHH1_k127_3289650_2 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000003799 219.0
YHH1_k127_3289650_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000002839 121.0
YHH1_k127_3289650_4 Belongs to the Nudix hydrolase family K12944 - - 0.000000000000000000000000006265 115.0
YHH1_k127_3289650_5 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000001956 113.0
YHH1_k127_3289650_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000003528 115.0
YHH1_k127_3289650_7 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000006669 91.0
YHH1_k127_3289650_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000007534 77.0
YHH1_k127_3289650_9 Cupin - - - 0.00000000471 64.0
YHH1_k127_3326292_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region - - - 0.000000000000000000000000000000000000000000000000000000000000000000002385 247.0
YHH1_k127_3326292_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003438 237.0
YHH1_k127_3326292_2 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000004426 209.0
YHH1_k127_3326292_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine - - - 0.00000000000000000000000000000000002896 150.0
YHH1_k127_3326292_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000002728 126.0
YHH1_k127_3326292_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000002251 55.0
YHH1_k127_3356817_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 1.852e-202 664.0
YHH1_k127_3356817_1 Transglutaminase-like domain - - - 0.000000000001195 77.0
YHH1_k127_3356817_2 Bacterial Ig-like domain - - - 0.00000000008483 75.0
YHH1_k127_3356817_3 - - - - 0.00000006261 66.0
YHH1_k127_3426267_0 Hsp70 protein K04043 - - 3.348e-239 755.0
YHH1_k127_3426267_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 314.0
YHH1_k127_3426267_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003222 283.0
YHH1_k127_3426267_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000001495 199.0
YHH1_k127_3426267_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000001264 80.0
YHH1_k127_3426267_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000004706 51.0
YHH1_k127_3593505_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000003495 153.0
YHH1_k127_3593505_1 4-amino-4-deoxy-L-arabinose transferase - - - 0.000000601 61.0
YHH1_k127_3831135_0 recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000001563 189.0
YHH1_k127_3831135_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000001984 182.0
YHH1_k127_3831135_2 Tetratricopeptide repeat - - - 0.00000000000000002154 92.0
YHH1_k127_3852652_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 553.0
YHH1_k127_3852652_1 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 407.0
YHH1_k127_3852652_10 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000003773 105.0
YHH1_k127_3852652_11 Yqey-like protein K09117 - - 0.0000000000000000002476 93.0
YHH1_k127_3852652_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000002921 81.0
YHH1_k127_3852652_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000444 83.0
YHH1_k127_3852652_14 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000398 49.0
YHH1_k127_3852652_15 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0003507 45.0
YHH1_k127_3852652_2 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001882 278.0
YHH1_k127_3852652_3 pfkB family carbohydrate kinase K00856,K22026 - 2.7.1.20,2.7.1.213,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000001958 273.0
YHH1_k127_3852652_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000764 255.0
YHH1_k127_3852652_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000001445 238.0
YHH1_k127_3852652_6 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000004465 203.0
YHH1_k127_3852652_7 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000004876 197.0
YHH1_k127_3852652_8 - - - - 0.000000000000000000000000000000000000000004348 165.0
YHH1_k127_3852652_9 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000009526 110.0
YHH1_k127_3893030_0 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 301.0
YHH1_k127_3893030_1 protein involved in tolerance to divalent cations K03926 - - 0.0000000000000007035 81.0
YHH1_k127_3893030_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000002361 63.0
YHH1_k127_3893030_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000004758 60.0
YHH1_k127_3928385_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 419.0
YHH1_k127_3928385_1 PIN domain - - - 0.0000000000001128 76.0
YHH1_k127_3928385_2 Metal-dependent hydrolases of the beta-lactamase superfamily III - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000002627 59.0
YHH1_k127_3928385_3 toxin-antitoxin pair type II binding K19156 - - 0.000695 46.0
YHH1_k127_397409_0 type II secretion system protein E K02243,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 455.0
YHH1_k127_397409_1 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 357.0
YHH1_k127_397409_10 COG4972 Tfp pilus assembly protein, ATPase PilM K02662 - - 0.00000001656 67.0
YHH1_k127_397409_11 Pilus assembly protein PilX K02673 - - 0.00000015 64.0
YHH1_k127_397409_12 Prokaryotic N-terminal methylation motif - - - 0.000001382 56.0
YHH1_k127_397409_13 Pfam:N_methyl_2 - - - 0.00001698 54.0
YHH1_k127_397409_2 COGs COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
YHH1_k127_397409_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009704 268.0
YHH1_k127_397409_4 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009603 244.0
YHH1_k127_397409_5 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000003534 205.0
YHH1_k127_397409_6 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000002277 192.0
YHH1_k127_397409_7 PFAM response regulator receiver K03413 - - 0.0000000000000000000003893 100.0
YHH1_k127_397409_8 Prokaryotic N-terminal methylation motif - - - 0.00000000000001831 86.0
YHH1_k127_397409_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000007279 76.0
YHH1_k127_4009147_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 304.0
YHH1_k127_4009147_1 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000007857 200.0
YHH1_k127_4009147_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000006646 133.0
YHH1_k127_4009147_3 PFAM Glycosyl transferase family 2 - - - 0.000000007252 65.0
YHH1_k127_4019315_0 membrane transporter protein - - - 0.000000000001039 75.0
YHH1_k127_4019315_1 Chaperone - - - 0.000000000002804 77.0
YHH1_k127_406037_0 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.000000000006748 77.0
YHH1_k127_406037_1 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.0000000001599 72.0
YHH1_k127_4143374_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001458 306.0
YHH1_k127_4143374_1 Major Facilitator Superfamily - - - 0.000000000000000003665 94.0
YHH1_k127_4143374_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0001589 49.0
YHH1_k127_4144309_0 ATP-grasp domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 292.0
YHH1_k127_4144309_1 Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001534 271.0
YHH1_k127_4144309_2 RmlD substrate binding domain - - - 0.0000000000000000000000000000004389 132.0
YHH1_k127_4163157_0 - - - - 0.0000000000000000000000000000000000000000001586 183.0
YHH1_k127_4163157_1 phosphatidylinositol metabolic process K00728 - 2.4.1.109 0.00000000000000000002474 106.0
YHH1_k127_4163157_2 Glycogen debranching enzyme K05988,K07019 - 3.2.1.11 0.000000000000000008656 98.0
YHH1_k127_419689_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000006532 222.0
YHH1_k127_419689_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000005462 127.0
YHH1_k127_419689_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000001341 105.0
YHH1_k127_419689_3 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.00000000000001357 84.0
YHH1_k127_4208055_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.524e-252 803.0
YHH1_k127_4208055_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000001066 172.0
YHH1_k127_4208055_2 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000001968 158.0
YHH1_k127_4208055_3 PFAM phosphoribosyltransferase K07101 - - 0.000000000000000000000000001532 119.0
YHH1_k127_4208055_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000003196 106.0
YHH1_k127_4208055_5 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.00000000000000000000002465 108.0
YHH1_k127_4208055_6 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000006965 80.0
YHH1_k127_4208055_7 metal-dependent phosphohydrolase HD - - - 0.000005234 56.0
YHH1_k127_4208055_8 - - - - 0.0001116 51.0
YHH1_k127_42303_0 Glycosyl transferases group 1 - - - 0.00000000000000006928 94.0
YHH1_k127_4352237_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 405.0
YHH1_k127_4467959_0 Peptidase family M48 - - - 0.0000007827 64.0
YHH1_k127_4481458_0 PFAM Peptidase family M48 - - - 0.00000000000000000000000000002334 124.0
YHH1_k127_4481458_1 Alpha-2-Macroglobulin K06894 - - 0.000000000000000000000002375 121.0
YHH1_k127_4611258_0 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 3.788e-213 670.0
YHH1_k127_4611258_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 517.0
YHH1_k127_4611258_10 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000006149 79.0
YHH1_k127_4611258_11 Domain of unknown function (DUF4115) - - - 0.0000000000001667 78.0
YHH1_k127_4611258_12 nitrite reductase [NAD(P)H] activity K05710 - - 0.0000000000002516 74.0
YHH1_k127_4611258_13 Haloacid dehalogenase-like hydrolase - - - 0.000000000001523 77.0
YHH1_k127_4611258_14 TIGRFAM addiction module toxin, RelE StbE family K06218 - - 0.00000000001892 67.0
YHH1_k127_4611258_15 Antitoxin component of a toxin-antitoxin (TA) module K19159 GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351 - 0.0000006053 55.0
YHH1_k127_4611258_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000956 464.0
YHH1_k127_4611258_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 457.0
YHH1_k127_4611258_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 306.0
YHH1_k127_4611258_5 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004463 276.0
YHH1_k127_4611258_6 ATPases associated with a variety of cellular activities K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
YHH1_k127_4611258_7 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000003969 161.0
YHH1_k127_4611258_8 GlcNAc-PI de-N-acetylase K22135 - - 0.0000000000000000000000001081 120.0
YHH1_k127_4611258_9 TIGRFAM FeS assembly protein SufD K09015 - - 0.0000000000000000000002045 105.0
YHH1_k127_4624177_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 314.0
YHH1_k127_4632221_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003717 286.0
YHH1_k127_4632221_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006599 252.0
YHH1_k127_4632221_2 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.000000000000000000000000000000000003111 143.0
YHH1_k127_4632221_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000005396 106.0
YHH1_k127_4632221_4 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000001736 78.0
YHH1_k127_4635985_0 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
YHH1_k127_4635985_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000003604 110.0
YHH1_k127_4635985_2 phosphoesterase, PA-phosphatase related - - - 0.0001533 51.0
YHH1_k127_4732304_0 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004725 548.0
YHH1_k127_4732304_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002469 272.0
YHH1_k127_4732304_10 Endonuclease containing a URI domain K01154,K07461 - 3.1.21.3 0.00000000000000004861 83.0
YHH1_k127_4732304_11 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000003681 85.0
YHH1_k127_4732304_12 filamentation induced by cAMP protein Fic - - - 0.00000000000004389 80.0
YHH1_k127_4732304_14 peptidase - - - 0.00000000002368 72.0
YHH1_k127_4732304_15 - - - - 0.000000009546 57.0
YHH1_k127_4732304_16 Belongs to the Fur family K03711 - - 0.0000002803 58.0
YHH1_k127_4732304_17 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000002674 58.0
YHH1_k127_4732304_18 - - - - 0.00002482 55.0
YHH1_k127_4732304_2 Fic family K04095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003644 241.0
YHH1_k127_4732304_3 Fic family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
YHH1_k127_4732304_4 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.00000000000000000000000000000000000000000000000000000006073 200.0
YHH1_k127_4732304_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000001266 186.0
YHH1_k127_4732304_6 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000001001 114.0
YHH1_k127_4732304_7 SMART Metal-dependent phosphohydrolase, HD region K07023 - - 0.0000000000000000000000001414 113.0
YHH1_k127_4732304_8 domain protein K07004,K20276 - - 0.0000000000000000000000255 112.0
YHH1_k127_4732304_9 EamA-like transporter family - - - 0.00000000000000000000006724 109.0
YHH1_k127_483930_0 ATPase (AAA superfamily) K07133 - - 0.000000000000000000000000000000000000000008073 160.0
YHH1_k127_483930_1 Domain of unknown function (DUF4349) - - - 0.00000000000000000000001007 106.0
YHH1_k127_4841899_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000009682 111.0
YHH1_k127_4841899_1 Methyltransferase domain - - - 0.00000000000000000001532 98.0
YHH1_k127_4848430_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000002469 169.0
YHH1_k127_4848430_1 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.0000000000004161 74.0
YHH1_k127_4848430_2 HAD-hyrolase-like - - - 0.0004975 47.0
YHH1_k127_4849730_0 helicase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 422.0
YHH1_k127_4849730_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000003999 205.0
YHH1_k127_4849730_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000027 109.0
YHH1_k127_4849730_3 ribosomal protein - - - 0.00000000000002569 77.0
YHH1_k127_4867129_0 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000714 262.0
YHH1_k127_4867129_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000006252 58.0
YHH1_k127_4912981_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
YHH1_k127_4912981_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000002371 86.0
YHH1_k127_4914087_0 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000005587 263.0
YHH1_k127_4914087_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000125 186.0
YHH1_k127_5047827_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 347.0
YHH1_k127_5047827_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 323.0
YHH1_k127_5047827_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000001221 162.0
YHH1_k127_5095154_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 350.0
YHH1_k127_5095154_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 303.0
YHH1_k127_5095154_2 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K02823,K17828 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 267.0
YHH1_k127_5095154_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000007078 163.0
YHH1_k127_5095154_4 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) K01955 - 6.3.5.5 0.000000000000000000000000001908 118.0
YHH1_k127_5095154_5 orotidine-5'-phosphate decarboxylase activity K01591,K13421 GO:0000003,GO:0000909,GO:0002119,GO:0002164,GO:0003006,GO:0003674,GO:0003824,GO:0004588,GO:0004590,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006996,GO:0007033,GO:0007040,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009314,GO:0009405,GO:0009411,GO:0009416,GO:0009628,GO:0009653,GO:0009790,GO:0009791,GO:0009792,GO:0009887,GO:0009987,GO:0010033,GO:0010165,GO:0010212,GO:0010225,GO:0010259,GO:0010332,GO:0014070,GO:0016043,GO:0016477,GO:0016740,GO:0016757,GO:0016763,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0019860,GO:0019953,GO:0022414,GO:0022610,GO:0030447,GO:0030582,GO:0030584,GO:0031012,GO:0032501,GO:0032502,GO:0032504,GO:0034404,GO:0034641,GO:0034654,GO:0035239,GO:0035295,GO:0040007,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042455,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044182,GO:0044205,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044703,GO:0044706,GO:0045927,GO:0046049,GO:0046107,GO:0046108,GO:0046109,GO:0046112,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0048513,GO:0048518,GO:0048546,GO:0048557,GO:0048562,GO:0048565,GO:0048566,GO:0048568,GO:0048598,GO:0048608,GO:0048609,GO:0048638,GO:0048639,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050896,GO:0051094,GO:0051179,GO:0051239,GO:0051240,GO:0051674,GO:0051704,GO:0055086,GO:0055123,GO:0060378,GO:0061458,GO:0062039,GO:0062040,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0075259,GO:0080171,GO:0090407,GO:0090727,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.10,4.1.1.23 0.000009475 49.0
YHH1_k127_509923_0 CoA binding domain - - - 7.125e-316 990.0
YHH1_k127_509923_1 including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 321.0
YHH1_k127_509923_2 haloacid dehalogenase-like hydrolase - - - 0.0000000008792 68.0
YHH1_k127_5204225_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
YHH1_k127_5204225_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000001344 213.0
YHH1_k127_5204225_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000001182 109.0
YHH1_k127_5204225_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000003741 108.0
YHH1_k127_5211620_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000001375 108.0
YHH1_k127_5211620_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000001162 113.0
YHH1_k127_5211620_2 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000286 63.0
YHH1_k127_5362001_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 620.0
YHH1_k127_5362001_1 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
YHH1_k127_5362001_10 TRANSCRIPTIONal - - - 0.00000000000000000007672 94.0
YHH1_k127_5362001_11 Thioredoxin reductase K00384 - 1.8.1.9 0.00000000000001318 75.0
YHH1_k127_5362001_12 Vitamin k epoxide reductase K00368 - 1.7.2.1 0.000000007842 63.0
YHH1_k127_5362001_13 cyclic nucleotide binding K01420,K10914 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000004778 62.0
YHH1_k127_5362001_14 CAAX amino terminal protease family protein K07052 - - 0.00001764 55.0
YHH1_k127_5362001_15 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00009981 49.0
YHH1_k127_5362001_2 Biogenesis protein K02275,K09792,K17686 - 1.9.3.1,3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000003018 227.0
YHH1_k127_5362001_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000002756 168.0
YHH1_k127_5362001_4 Thioredoxin K03671 - - 0.0000000000000000000000000000000000001961 143.0
YHH1_k127_5362001_5 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000001629 145.0
YHH1_k127_5362001_6 Domain of unknown function (DUF4870) - - - 0.00000000000000000000000000000000004432 136.0
YHH1_k127_5362001_7 Thioredoxin - - - 0.0000000000000000000000000000000003375 141.0
YHH1_k127_5362001_8 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000006151 130.0
YHH1_k127_5362001_9 PFAM Phosphoribosyl transferase domain - - - 0.00000000000000000000002147 107.0
YHH1_k127_5481875_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 3.659e-222 706.0
YHH1_k127_5481875_1 PFAM type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 309.0
YHH1_k127_5481875_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000119 239.0
YHH1_k127_5481875_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000009465 89.0
YHH1_k127_5499103_0 oligosaccharyl transferase activity - - - 0.0000000000000004491 91.0
YHH1_k127_5499103_1 - - - - 0.00000000001584 77.0
YHH1_k127_5501186_0 ATP dependent DNA ligase C terminal region K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 432.0
YHH1_k127_5501186_1 Filamentation induced by cAMP protein fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 303.0
YHH1_k127_5501186_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 297.0
YHH1_k127_5501186_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 293.0
YHH1_k127_5501186_4 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000002079 98.0
YHH1_k127_5551442_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 351.0
YHH1_k127_5551442_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000554 243.0
YHH1_k127_5551442_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000001512 231.0
YHH1_k127_5551442_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000001215 54.0
YHH1_k127_5611245_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 324.0
YHH1_k127_5611245_1 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000009725 209.0
YHH1_k127_5611245_2 S23 ribosomal protein - - - 0.000000000000000001203 90.0
YHH1_k127_5622366_0 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K04075,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9,6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 562.0
YHH1_k127_5622366_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 344.0
YHH1_k127_5622366_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000001544 231.0
YHH1_k127_5622366_3 Domain of unknown function (DUF1972) - - - 0.0000000000000000000000000000000000000000000000000000000000002676 224.0
YHH1_k127_5622366_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000001168 187.0
YHH1_k127_5622366_5 Glycosyl transferase family 2 K00786 - - 0.00000000000000000000000000000000000000001493 161.0
YHH1_k127_5622366_6 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000002016 147.0
YHH1_k127_5622366_7 Glycosyl transferases group 1 - - - 0.0000000000005645 80.0
YHH1_k127_5622366_8 PFAM O-antigen - - - 0.00003286 57.0
YHH1_k127_5622366_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0002468 53.0
YHH1_k127_5652999_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 5.457e-252 796.0
YHH1_k127_5652999_1 Mur ligase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 347.0
YHH1_k127_5652999_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 293.0
YHH1_k127_5652999_3 PFAM LemA - - - 0.000000000000000000000000000000000000000000000000000000000001876 214.0
YHH1_k127_5652999_4 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000001083 153.0
YHH1_k127_5663292_0 Psort location Cytoplasmic, score K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 306.0
YHH1_k127_5663292_1 glycosyl transferase family 8 - - - 0.00000000000000000000000000000000000000000000000000000002117 207.0
YHH1_k127_5663292_2 belongs to the Fur family K09825 GO:0003674,GO:0003700,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2000374,GO:2001141 - 0.00000000000000000000000000000000000001969 149.0
YHH1_k127_5663292_3 membrane protein (DUF2079) - - - 0.0000000000000000003069 99.0
YHH1_k127_5663292_4 Transposase IS200 like K07491 - - 0.00000000000000005165 84.0
YHH1_k127_5857490_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 436.0
YHH1_k127_5857490_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 391.0
YHH1_k127_5857490_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001118 263.0
YHH1_k127_5859742_0 Maf-like protein K06287 - - 0.00000000000000000009464 99.0
YHH1_k127_5859742_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 0.000000000000001299 91.0
YHH1_k127_5975961_0 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 355.0
YHH1_k127_5975961_1 type II secretion system protein E K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000006892 216.0
YHH1_k127_5980717_0 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000004244 137.0
YHH1_k127_5980717_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000007819 62.0
YHH1_k127_6101907_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 567.0
YHH1_k127_6101907_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0000049,GO:0001731,GO:0002181,GO:0002183,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006413,GO:0006417,GO:0006446,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031334,GO:0032268,GO:0032270,GO:0032790,GO:0032984,GO:0032988,GO:0032991,GO:0034248,GO:0034250,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043254,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045727,GO:0045948,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065003,GO:0065007,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901193,GO:1901195,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:1904688,GO:1904690,GO:1990856,GO:1990904,GO:2000112,GO:2000765,GO:2000767 - 0.0000000000000000000000000000000000000000002122 164.0
YHH1_k127_6101907_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000005323 128.0
YHH1_k127_6101907_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000006246 107.0
YHH1_k127_6101907_4 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000004234 51.0
YHH1_k127_6146308_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 436.0
YHH1_k127_6146308_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000004978 157.0
YHH1_k127_6147257_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000001564 175.0
YHH1_k127_6147257_1 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000003577 139.0
YHH1_k127_6147257_2 Methyltransferase domain - - - 0.000000000000000000000007915 111.0
YHH1_k127_6233742_0 PFAM Peptidase family M50 - - - 0.0000000000000000000000000000000000000000001525 167.0
YHH1_k127_6233742_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.0000000000000000000000104 116.0
YHH1_k127_6233742_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000002575 81.0
YHH1_k127_6233742_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0003834 46.0
YHH1_k127_6238015_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 606.0
YHH1_k127_6238015_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001531 276.0
YHH1_k127_6238015_10 Tellurite resistance protein TehB - - - 0.00000004452 57.0
YHH1_k127_6238015_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000007303 265.0
YHH1_k127_6238015_3 PFAM VanW family protein - - - 0.0000000000000000000000000000000000000000000000000000000002075 221.0
YHH1_k127_6238015_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0019899,GO:0030312,GO:0031323,GO:0031326,GO:0033554,GO:0034605,GO:0035375,GO:0035966,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000004066 113.0
YHH1_k127_6238015_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000001231 95.0
YHH1_k127_6238015_6 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000001652 100.0
YHH1_k127_6238015_7 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000000004897 83.0
YHH1_k127_6238015_8 lipolytic protein G-D-S-L family - - - 0.000000000000001098 89.0
YHH1_k127_6238015_9 nucleotidyltransferase activity - - - 0.0000000000001821 81.0
YHH1_k127_6272163_0 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003849 276.0
YHH1_k127_6272163_1 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000009115 130.0
YHH1_k127_6272163_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000002426 106.0
YHH1_k127_6272163_3 Glycosyltransferase family 87 K13671 - - 0.00000000000007856 83.0
YHH1_k127_6272163_4 Glycosyl transferases group 1 K03280 - 2.4.1.56 0.000000000001416 74.0
YHH1_k127_6272163_5 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.000000000001421 76.0
YHH1_k127_6272163_6 LysM domain K21687 - - 0.000000000002758 75.0
YHH1_k127_6272163_7 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00001759 57.0
YHH1_k127_6273224_0 UMP kinase activity K00947,K09903 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030151,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000003226 224.0
YHH1_k127_6273224_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000001803 194.0
YHH1_k127_6324673_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 7.583e-253 809.0
YHH1_k127_6324673_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 435.0
YHH1_k127_6324673_10 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.0000000000000000000000001109 113.0
YHH1_k127_6324673_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 415.0
YHH1_k127_6324673_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 365.0
YHH1_k127_6324673_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 304.0
YHH1_k127_6324673_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005478 256.0
YHH1_k127_6324673_6 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000006888 241.0
YHH1_k127_6324673_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000159 216.0
YHH1_k127_6324673_8 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.00000000000000000000000000000000000000006971 156.0
YHH1_k127_6324673_9 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000007217 130.0
YHH1_k127_6616530_0 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 402.0
YHH1_k127_6616530_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 387.0
YHH1_k127_6616530_2 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 326.0
YHH1_k127_6616530_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000001678 109.0
YHH1_k127_6616530_4 NUDIX domain - - - 0.000000000000003221 81.0
YHH1_k127_6616530_5 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000001727 58.0
YHH1_k127_671576_0 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000006997 128.0
YHH1_k127_671576_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000007313 116.0
YHH1_k127_671576_2 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000008977 111.0
YHH1_k127_671576_3 Polysaccharide biosynthesis protein - - - 0.00000000000000003384 94.0
YHH1_k127_671576_4 Polymerase - - - 0.00007929 53.0
YHH1_k127_6757441_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.066e-284 889.0
YHH1_k127_6886323_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000002913 238.0
YHH1_k127_6886323_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000001087 115.0
YHH1_k127_6886323_2 Glycosyl hydrolases family 39 K01198 - 3.2.1.37 0.0000000000000000001396 103.0
YHH1_k127_6886323_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000004335 82.0
YHH1_k127_6886323_4 Protein conserved in bacteria K20276 - - 0.000000008964 67.0
YHH1_k127_6886323_5 Binds directly to 16S ribosomal RNA K02968 - - 0.0002039 47.0
YHH1_k127_6886323_6 calcium ion binding - GO:0002009,GO:0002165,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0007275,GO:0007424,GO:0007444,GO:0007472,GO:0007475,GO:0007476,GO:0007552,GO:0007560,GO:0007591,GO:0008150,GO:0008362,GO:0008587,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0022404,GO:0031012,GO:0032501,GO:0032502,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040003,GO:0040005,GO:0042303,GO:0042335,GO:0044421,GO:0044719,GO:0048513,GO:0048563,GO:0048569,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0060429,GO:0060541,GO:0060562,GO:0065007,GO:0065008,GO:0090066 - 0.0008612 50.0
YHH1_k127_6918476_0 Hydrolase Cof - - - 0.0000000000000001584 89.0
YHH1_k127_6918476_1 seryl-tRNA synthetase K01875 - 6.1.1.11 0.00000000000335 67.0
YHH1_k127_6918476_2 PQ loop repeat K15383 - - 0.000001833 53.0
YHH1_k127_697309_0 homoserine transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000001466 207.0
YHH1_k127_697309_1 - - - - 0.0000007086 54.0
YHH1_k127_7037409_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 313.0
YHH1_k127_7037409_1 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002023 270.0
YHH1_k127_7037409_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000119 108.0
YHH1_k127_7037409_11 heme binding - - - 0.0000000000000000000001725 102.0
YHH1_k127_7037409_12 - - - - 0.00000000000000000423 93.0
YHH1_k127_7037409_13 Glycosyl hydrolase - - - 0.000000000000001146 89.0
YHH1_k127_7037409_14 response regulator K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000004719 79.0
YHH1_k127_7037409_15 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000001521 71.0
YHH1_k127_7037409_16 positive regulation of proteasomal protein catabolic process - - - 0.0000000001602 74.0
YHH1_k127_7037409_17 esterase of the alpha beta hydrolase fold K07002 - - 0.0000002744 60.0
YHH1_k127_7037409_18 MazG nucleotide pyrophosphohydrolase domain - - - 0.000005992 53.0
YHH1_k127_7037409_2 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000003674 238.0
YHH1_k127_7037409_3 Dna alkylation repair - - - 0.000000000000000000000000000000000000000000000000000000000000002621 226.0
YHH1_k127_7037409_4 Belongs to the FPP GGPP synthase family K00805,K02523,K13787,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000001958 202.0
YHH1_k127_7037409_5 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000002985 188.0
YHH1_k127_7037409_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K00556,K03218,K03437,K15333 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.185,2.1.1.34 0.000000000000000000000000000000000000001233 154.0
YHH1_k127_7037409_7 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000001683 143.0
YHH1_k127_7037409_8 Protein of unknown function DUF84 - - - 0.0000000000000000000000000006644 119.0
YHH1_k127_7037409_9 Tetratricopeptide repeat - - - 0.000000000000000000000003659 119.0
YHH1_k127_7038449_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 485.0
YHH1_k127_7038449_1 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000766 483.0
YHH1_k127_7038449_2 Belongs to the aldehyde dehydrogenase family K00131 - 1.2.1.9 0.0000000000000000000000000000000002651 139.0
YHH1_k127_7038449_4 Copper binding proteins, plastocyanin/azurin family - - - 0.0000005238 59.0
YHH1_k127_7052843_0 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 599.0
YHH1_k127_7052843_1 Elongation factor G C-terminus K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 518.0
YHH1_k127_7061240_0 Protein of unknown function (DUF998) - - - 0.00000003899 57.0
YHH1_k127_7081849_0 Domain of unknown function (DUF4349) - - - 0.000000000001307 76.0
YHH1_k127_7081983_0 HEPN domain - - - 0.000000000000000004422 88.0
YHH1_k127_7081983_1 Nucleotidyltransferase domain - - - 0.0000000007025 64.0
YHH1_k127_7081983_2 Psort location Cytoplasmic, score - - - 0.000001289 51.0
YHH1_k127_7097840_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 423.0
YHH1_k127_7097840_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 332.0
YHH1_k127_7097840_10 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000007184 167.0
YHH1_k127_7097840_11 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.0000000000000000000000000000000000006883 144.0
YHH1_k127_7097840_12 Transposase IS200 like K07491 - - 0.0000000000000000000000000000001196 133.0
YHH1_k127_7097840_13 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000001507 129.0
YHH1_k127_7097840_14 Glycosyltransferase like family 2 K07011,K20444 - - 0.0000000000000000000001294 108.0
YHH1_k127_7097840_15 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000004872 106.0
YHH1_k127_7097840_16 YGGT family - - - 0.0000000000000000000007315 99.0
YHH1_k127_7097840_17 Glycosyl hydrolases family 32 N-terminal domain K01193 - 3.2.1.26 0.00000000000000003635 92.0
YHH1_k127_7097840_18 PFAM Excinuclease ABC, C subunit K07461 - - 0.000000000000000472 81.0
YHH1_k127_7097840_19 redox-active disulfide protein 2 - - - 0.000000000000006999 78.0
YHH1_k127_7097840_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005838 334.0
YHH1_k127_7097840_20 arsR family transcriptional regulator K03892 - - 0.0000000000006677 72.0
YHH1_k127_7097840_21 - - - - 0.00000000127 64.0
YHH1_k127_7097840_22 Protein of unknown function (DUF3096) - - - 0.0000184 48.0
YHH1_k127_7097840_23 - - - - 0.00004517 49.0
YHH1_k127_7097840_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 308.0
YHH1_k127_7097840_4 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 300.0
YHH1_k127_7097840_5 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 295.0
YHH1_k127_7097840_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 286.0
YHH1_k127_7097840_7 ABC transporter K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002945 264.0
YHH1_k127_7097840_8 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000009311 188.0
YHH1_k127_7097840_9 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000000004696 161.0
YHH1_k127_7112239_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000009981 151.0
YHH1_k127_7112239_1 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000005622 100.0
YHH1_k127_7112239_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000006601 106.0
YHH1_k127_7177387_0 NAD-dependent epimerase dehydratase K01784,K12454 - 5.1.3.10,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 397.0
YHH1_k127_7177387_1 alcohol dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000002715 230.0
YHH1_k127_7177387_2 transferase activity, transferring glycosyl groups K00721 - 2.4.1.83 0.00000000000000000006145 98.0
YHH1_k127_7177387_3 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.00000000000000000006836 92.0
YHH1_k127_7254395_0 PFAM Peptidase M11 gametolysin - - - 0.000005403 59.0
YHH1_k127_7283836_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004801 259.0
YHH1_k127_7283836_1 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000003278 242.0
YHH1_k127_7283836_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000007179 162.0
YHH1_k127_7283836_3 Glycosyl transferases group 1 K21001 - - 0.00000000000000000000000000000000000549 152.0
YHH1_k127_7283836_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000001376 65.0
YHH1_k127_7283836_5 mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.000001286 50.0
YHH1_k127_729918_0 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000001034 231.0
YHH1_k127_729918_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000002019 125.0
YHH1_k127_729918_2 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.000000000000000000002315 104.0
YHH1_k127_729918_3 mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.000002155 59.0
YHH1_k127_729918_4 phosphoglucosamine mutase activity K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00008544 47.0
YHH1_k127_7314453_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.679e-196 626.0
YHH1_k127_7314453_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000003601 61.0
YHH1_k127_7332176_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000285 235.0
YHH1_k127_7332176_1 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000004034 171.0
YHH1_k127_7332176_2 Cytidylyltransferase-like K02201 - 2.7.7.3 0.00000000000000000000001193 113.0
YHH1_k127_7332176_3 Helix-turn-helix domain - - - 0.0000009819 52.0
YHH1_k127_7373907_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 612.0
YHH1_k127_7373907_1 RmuC family K09760 - - 0.00000000000000000000816 97.0
YHH1_k127_7383316_0 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000002139 87.0
YHH1_k127_7383316_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000167 75.0
YHH1_k127_7383316_2 Sortase family K07284 - 3.4.22.70 0.00009697 55.0
YHH1_k127_738564_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000002081 144.0
YHH1_k127_738564_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000005958 109.0
YHH1_k127_738564_2 O-Antigen ligase - - - 0.000001693 61.0
YHH1_k127_7537099_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
YHH1_k127_7620361_0 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000002508 255.0
YHH1_k127_7620361_1 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000001995 177.0
YHH1_k127_7620361_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762,K13421 - 2.4.2.10,4.1.1.23 0.0000000000000000000000009893 107.0
YHH1_k127_7644497_0 thiamine pyrophosphokinase K00949 - 2.7.6.2 0.00000000000000000000000000000000000004351 152.0
YHH1_k127_7644497_1 competence protein - - - 0.0000000000000000000000000000003783 131.0
YHH1_k127_7644497_2 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.000000000000000000000000009001 118.0
YHH1_k127_7644497_3 GDP-mannose mannosyl hydrolase activity K01515,K03574,K13669,K19710 GO:0000026,GO:0000030,GO:0003674,GO:0003824,GO:0004376,GO:0004377,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0043750,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0070085,GO:0071704,GO:0097502,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.7.53,3.6.1.13,3.6.1.55 0.0000000000000000007753 93.0
YHH1_k127_7644497_4 AraC-like ligand binding domain - - - 0.0000000000000001028 84.0
YHH1_k127_7644497_5 GIY-YIG catalytic domain - - - 0.0000000000000003735 81.0
YHH1_k127_7644497_6 IA, variant 1 K01091,K06019 - 3.1.3.18,3.6.1.1 0.0000000000001 79.0
YHH1_k127_7644497_7 Endonuclease containing a URI domain K01154,K07461 - 3.1.21.3 0.000000000001563 70.0
YHH1_k127_7644497_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000308 53.0
YHH1_k127_7644497_9 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000005444 58.0
YHH1_k127_7697115_0 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 308.0
YHH1_k127_7697115_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000004712 120.0
YHH1_k127_7697115_2 PFAM Tetratricopeptide - - - 0.000002597 61.0
YHH1_k127_7697115_3 general secretion pathway protein G K02456 - - 0.00001672 54.0
YHH1_k127_7697115_4 Prokaryotic N-terminal methylation motif K02456 - - 0.0002332 50.0
YHH1_k127_7697115_5 best DB hits PFAM PF00114 - - - 0.0005061 44.0
YHH1_k127_7717337_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 301.0
YHH1_k127_7717337_1 Phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.00005352 53.0
YHH1_k127_7727284_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 455.0
YHH1_k127_7727284_1 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000001573 113.0
YHH1_k127_7727284_2 Endonuclease containing a URI domain K07461 - - 0.000000000001664 72.0
YHH1_k127_7773016_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000003537 238.0
YHH1_k127_7773016_1 Uncharacterised protein family UPF0052 - - - 0.000000000000000000000000000000005066 131.0
YHH1_k127_7773016_2 cysteine protease - - - 0.0000005063 61.0
YHH1_k127_7773016_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000983 56.0
YHH1_k127_7790807_0 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000001629 228.0
YHH1_k127_7790807_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000207 203.0
YHH1_k127_7790807_2 PIN domain - - - 0.0000000000005399 74.0
YHH1_k127_7846091_0 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) K01955 - 6.3.5.5 2.246e-305 959.0
YHH1_k127_7846091_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 560.0
YHH1_k127_7846091_10 IA, variant 3 K07025,K20866 - 3.1.3.10 0.0000000003878 70.0
YHH1_k127_7846091_11 CopG antitoxin of type II toxin-antitoxin system - - - 0.0000004588 55.0
YHH1_k127_7846091_2 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 364.0
YHH1_k127_7846091_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 349.0
YHH1_k127_7846091_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002259 249.0
YHH1_k127_7846091_5 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000002437 233.0
YHH1_k127_7846091_6 macromolecule localization K01421,K01992,K09690 - - 0.00000000000000000000000000000000000000000000000000000002568 206.0
YHH1_k127_7846091_7 Psort location Cytoplasmic, score K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000003855 201.0
YHH1_k127_7846091_8 - K06148 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.00000000000000000000000000000000000000000000344 171.0
YHH1_k127_7846091_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000002082 85.0
YHH1_k127_7859882_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000135 217.0
YHH1_k127_7859882_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000004097 214.0
YHH1_k127_7859882_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000003326 181.0
YHH1_k127_7859882_3 Zinc-dependent metalloprotease - - - 0.0000000000000000000002627 108.0
YHH1_k127_7859882_4 Cysteine-rich secretory protein family - - - 0.0000000004688 68.0
YHH1_k127_7859882_5 Putative ATP-binding cassette K01992 - - 0.00000135 61.0
YHH1_k127_7862299_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.055e-196 642.0
YHH1_k127_7862299_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000008557 175.0
YHH1_k127_7862299_10 - - - - 0.00007181 52.0
YHH1_k127_7862299_2 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000004797 126.0
YHH1_k127_7862299_3 COG1525 Micrococcal nuclease (thermonuclease) homologs K16561 - - 0.000000000000000000001196 103.0
YHH1_k127_7862299_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000005125 93.0
YHH1_k127_7862299_5 Protein of unknown function (DUF2892) - - - 0.0000000000000003057 80.0
YHH1_k127_7862299_6 Staphylococcal nuclease homologues - - - 0.00000009107 60.0
YHH1_k127_7862299_7 membrane K00389 - - 0.0000001494 56.0
YHH1_k127_7862299_8 bacterial regulatory proteins, luxR family - - - 0.00000419 57.0
YHH1_k127_7890309_0 Fic family - - - 0.00000000000000000000000000000000000000000000000000000000000000537 227.0
YHH1_k127_7890309_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000001027 63.0
YHH1_k127_7933590_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 379.0
YHH1_k127_7933590_1 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000002071 256.0
YHH1_k127_7933590_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000831 220.0
YHH1_k127_7933590_3 NUDIX domain K01823 - 5.3.3.2 0.0000000000000000000000000000000000007499 147.0
YHH1_k127_7933590_4 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000002825 115.0
YHH1_k127_7933590_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000001192 80.0
YHH1_k127_7972749_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.918e-219 685.0
YHH1_k127_7972749_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000007167 85.0
YHH1_k127_7972749_2 PFAM CBS domain - - - 0.000000006268 62.0
YHH1_k127_7991199_0 ABC-type multidrug transport system, ATPase and permease components K06147,K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 465.0
YHH1_k127_7991199_1 PFAM DegT DnrJ EryC1 StrS aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000429 276.0
YHH1_k127_7991199_2 Glycosyl transferase family 2 K20534 - - 0.0006651 43.0
YHH1_k127_8000264_0 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 490.0
YHH1_k127_8000264_1 PhoQ Sensor - - - 0.00000000000000000000000000000000000001773 159.0
YHH1_k127_8020033_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000082 177.0
YHH1_k127_8020033_1 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000001458 138.0
YHH1_k127_8021786_0 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000002645 162.0
YHH1_k127_8021786_1 alpha-L-arabinofuranosidase - - - 0.000000000000000000000000000000000042 153.0
YHH1_k127_8021786_2 Peptidase S24-like K13280 - 3.4.21.89 0.000000000000468 82.0
YHH1_k127_8021786_3 Endonuclease I - - - 0.00000000007554 74.0
YHH1_k127_8021786_4 Camelysin metallo-endopeptidase - - - 0.00006929 55.0
YHH1_k127_8152772_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 441.0
YHH1_k127_8152772_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 301.0
YHH1_k127_8152772_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000001452 110.0
YHH1_k127_8152772_11 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000001314 109.0
YHH1_k127_8152772_12 Ribosomal protein L17 K02879 - - 0.000000000000000001087 93.0
YHH1_k127_8152772_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001033 74.0
YHH1_k127_8152772_14 Regulatory protein RecX K03565 - - 0.00002357 53.0
YHH1_k127_8152772_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000002769 271.0
YHH1_k127_8152772_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000002686 206.0
YHH1_k127_8152772_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000001111 203.0
YHH1_k127_8152772_5 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000007517 177.0
YHH1_k127_8152772_6 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000001204 156.0
YHH1_k127_8152772_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000001868 148.0
YHH1_k127_8152772_8 ribosomal protein K02871 GO:0000313,GO:0000315,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005761,GO:0005762,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0031974,GO:0032543,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013,GO:0071704,GO:0097159,GO:0098798,GO:0140053,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000003059 144.0
YHH1_k127_8152772_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000008624 128.0
YHH1_k127_8165806_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 3.35e-234 751.0
YHH1_k127_8165806_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 5.363e-201 637.0
YHH1_k127_8165806_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000832 224.0
YHH1_k127_8165806_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000003898 85.0
YHH1_k127_8165806_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000006051 79.0
YHH1_k127_8165806_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000164 49.0
YHH1_k127_8299939_0 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 392.0
YHH1_k127_8299939_1 Transport permease protein K01992,K09690 - - 0.0000000000000000000000000000000000000000000002997 176.0
YHH1_k127_8299939_10 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0000000000001925 79.0
YHH1_k127_8299939_11 Psort location Cytoplasmic, score - - - 0.0000000000003048 77.0
YHH1_k127_8299939_12 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000001493 70.0
YHH1_k127_8299939_13 nucleotidyltransferase activity - - - 0.00000000002651 68.0
YHH1_k127_8299939_14 PIN domain - - - 0.00000000002805 70.0
YHH1_k127_8299939_15 PFAM HEPN domain - - - 0.0000000009961 64.0
YHH1_k127_8299939_16 HEPN domain - - - 0.000000001678 63.0
YHH1_k127_8299939_17 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000003553 70.0
YHH1_k127_8299939_18 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000004258 59.0
YHH1_k127_8299939_19 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000002543 53.0
YHH1_k127_8299939_2 sugar transferase - - - 0.0000000000000000000000000000000000000000003584 168.0
YHH1_k127_8299939_20 nuclease activity K06218 - - 0.00003745 46.0
YHH1_k127_8299939_3 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000001173 141.0
YHH1_k127_8299939_4 30S ribosomal protein S23 - - - 0.0000000000000000000000000002108 118.0
YHH1_k127_8299939_5 Membrane protein insertase, YidC Oxa1 family K03217 - - 0.0000000000000000000000000006179 123.0
YHH1_k127_8299939_6 Wzt C-terminal domain K01990,K09691,K09693 - 3.6.3.40 0.000000000000000000000000002914 115.0
YHH1_k127_8299939_7 KH domain K06346 - - 0.00000000000000000001696 97.0
YHH1_k127_8299939_8 - - - - 0.00000000000000001655 86.0
YHH1_k127_8299939_9 Nucleotidyltransferase domain - - - 0.0000000000000000504 85.0
YHH1_k127_8330099_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001719 277.0
YHH1_k127_8330099_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000003525 233.0
YHH1_k127_8330099_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000001292 201.0
YHH1_k127_8398592_0 short-chain dehydrogenase reductase SDR K05886 - 1.1.1.276 0.00000000000000000000000000000000000009681 151.0
YHH1_k127_8398592_1 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000001447 75.0
YHH1_k127_8398592_2 L,D-transpeptidase catalytic domain - - - 0.0000003663 63.0
YHH1_k127_8398592_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0001961 53.0
YHH1_k127_8445570_0 Fic/DOC family - - - 0.00000000000000000000000000000000000004493 156.0
YHH1_k127_8445570_1 spore germination K08978 - - 0.00000000009221 72.0
YHH1_k127_8445570_2 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K01144 - 3.1.11.5 0.0000000002519 65.0
YHH1_k127_8513745_0 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 451.0
YHH1_k127_8513745_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003414 279.0
YHH1_k127_8513745_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000001446 127.0
YHH1_k127_8513745_3 Methionine biosynthesis protein MetW - - - 0.0000000000009554 78.0
YHH1_k127_8513745_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000212 57.0
YHH1_k127_8537430_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000194 135.0
YHH1_k127_8537430_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000228 126.0
YHH1_k127_8593675_0 Alpha-2-macroglobulin family K06894 - - 0.0000000000000000000000000000000000000000000000000000000000005912 237.0
YHH1_k127_8625266_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 338.0
YHH1_k127_8625266_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001199 272.0
YHH1_k127_8625266_2 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003253 267.0
YHH1_k127_8625266_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000005344 237.0
YHH1_k127_8625266_4 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000002169 186.0
YHH1_k127_8625266_5 HlyD family secretion protein K02005,K13888 - - 0.0000000000000000000000000004708 128.0
YHH1_k127_8625266_6 - - - - 0.00002464 52.0
YHH1_k127_8625266_7 - - - - 0.0009234 48.0
YHH1_k127_876597_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 317.0
YHH1_k127_876597_1 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.000000000000000000000000000000000000000000000000000000000000000000002351 251.0
YHH1_k127_876597_2 Hep Hag repeat protein - - - 0.000228 52.0
YHH1_k127_8794730_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000008098 218.0
YHH1_k127_8794730_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000003081 114.0
YHH1_k127_8794730_2 Transposase IS200 like - - - 0.00000000000000000000000008273 115.0
YHH1_k127_8802637_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003988 235.0
YHH1_k127_8802637_1 Integrase core domain protein - - - 0.0000000000000000000000000000000000000000000000008141 184.0
YHH1_k127_8802637_2 Type IV leader peptidase family K02236,K02654 - 3.4.23.43 0.0000000000000000000004307 98.0
YHH1_k127_8802637_3 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.0000000000000000004091 96.0
YHH1_k127_8802637_4 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.0000000000002097 75.0
YHH1_k127_8861689_0 Catalyzes the synthesis of GMP from XMP K01951,K03790 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.3.1.128,6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 539.0
YHH1_k127_8861689_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 288.0
YHH1_k127_8864127_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 419.0
YHH1_k127_8864127_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000002519 182.0
YHH1_k127_8864127_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790 - 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000333 146.0
YHH1_k127_8864127_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.00000000000000000000000000000001826 131.0
YHH1_k127_8925421_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000002918 218.0
YHH1_k127_8925421_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000006914 209.0
YHH1_k127_8925421_2 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000005596 131.0
YHH1_k127_8953273_0 Mannose-1-phosphate guanylyltransferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000005535 215.0
YHH1_k127_8953273_1 undecaprenyl-phosphate glucose phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000001637 186.0
YHH1_k127_8953273_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000002591 154.0
YHH1_k127_8953273_3 glycyl-tRNA aminoacylation - - - 0.0000000000000000000000000000000002459 135.0
YHH1_k127_8953273_4 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000007646 70.0
YHH1_k127_898006_0 Glycosyl transferase family 2 K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000001991 250.0
YHH1_k127_9040094_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030428,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 419.0
YHH1_k127_9040094_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 348.0
YHH1_k127_9040094_10 Homeodomain-like domain - - - 0.000001181 53.0
YHH1_k127_9040094_2 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 339.0
YHH1_k127_9040094_3 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000001156 213.0
YHH1_k127_9040094_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000009803 185.0
YHH1_k127_9040094_5 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000007067 187.0
YHH1_k127_9040094_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000003018 181.0
YHH1_k127_9040094_7 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000005642 101.0
YHH1_k127_9040094_8 Protein of unknown function DUF86 - - - 0.0000000000000000001416 92.0
YHH1_k127_9040094_9 - - - - 0.0000001062 57.0
YHH1_k127_9061342_0 regulatory protein K01090,K20074 - 3.1.3.16 0.0007052 54.0
YHH1_k127_9092283_0 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000003733 215.0
YHH1_k127_9170708_0 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000164 215.0
YHH1_k127_9170708_1 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000583 153.0
YHH1_k127_9170708_3 TAP-like protein - - - 0.0000000000000000000000000001083 124.0
YHH1_k127_9170708_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000005264 94.0
YHH1_k127_9170708_5 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000407 81.0
YHH1_k127_9229415_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 394.0
YHH1_k127_9229415_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 351.0
YHH1_k127_9229415_2 PolyA polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 310.0
YHH1_k127_9229415_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001727 288.0
YHH1_k127_9229415_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000244 204.0
YHH1_k127_9229415_5 D-alanyl-D-alanine carboxypeptidase K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000002514 174.0
YHH1_k127_9229415_6 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000000002142 98.0
YHH1_k127_9229415_7 nucleotidyltransferase activity K07061 - - 0.00000000000000000003417 98.0
YHH1_k127_9229415_8 - - - - 0.0001315 52.0
YHH1_k127_9446552_0 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000008559 148.0
YHH1_k127_9446552_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000001101 140.0
YHH1_k127_9446552_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000007461 102.0
YHH1_k127_9446552_3 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.0000000000006623 70.0
YHH1_k127_9483207_0 hexose biosynthetic process K01810 - 5.3.1.9 2.142e-298 922.0
YHH1_k127_9493750_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 593.0
YHH1_k127_9493750_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000003299 153.0
YHH1_k127_9493750_2 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.0000000000000000000000000000000006554 141.0
YHH1_k127_9499846_0 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000016 53.0
YHH1_k127_9540802_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000009068 269.0
YHH1_k127_9540802_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000002192 139.0
YHH1_k127_9540802_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000003906 80.0
YHH1_k127_9540802_3 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000184 48.0
YHH1_k127_9626483_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 444.0
YHH1_k127_9626483_1 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 406.0
YHH1_k127_9626483_2 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000001324 192.0
YHH1_k127_9631358_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 316.0
YHH1_k127_9631358_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003699 270.0
YHH1_k127_9631358_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000006909 187.0
YHH1_k127_9631358_3 Hexapeptide repeat of succinyl-transferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000001874 166.0
YHH1_k127_9631358_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000001464 77.0
YHH1_k127_9670908_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002816 276.0
YHH1_k127_9670908_1 Cysteine-rich secretory protein family - - - 0.000000000000000000000000006701 122.0
YHH1_k127_9670908_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87 0.00000000001112 69.0
YHH1_k127_9670908_3 peptidase M22 K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.0000000007609 63.0
YHH1_k127_9672060_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000004911 172.0
YHH1_k127_9672060_1 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000004554 176.0
YHH1_k127_9672060_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000824 64.0
YHH1_k127_9700211_0 Glycosyl transferase, family 2 - - - 0.000000000000000000000094 104.0
YHH1_k127_9700211_1 Iron-sulfur cluster-binding domain - - - 0.000000000004156 70.0
YHH1_k127_9700211_2 Glycosyltransferase like family 2 - - - 0.000000005622 67.0
YHH1_k127_9759481_0 PFAM glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 338.0
YHH1_k127_9759481_1 helix_turn_helix, Arsenical Resistance Operon Repressor K22042 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000967 65.0
YHH1_k127_9759481_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000001388 70.0
YHH1_k127_9759481_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00002396 52.0
YHH1_k127_9811235_0 BRO family, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000377 264.0
YHH1_k127_9811235_1 N-terminal domain of 16S rRNA methyltransferase RsmF K03500,K11392,K22446 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176,2.1.1.178 0.0000000000000000000000000000000000000000000000000000000000000000006908 233.0
YHH1_k127_9811235_2 acr, cog1430 K09005 - - 0.0000000000000000002 94.0
YHH1_k127_9811235_3 - - - - 0.0001479 46.0
YHH1_k127_982211_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000005759 221.0
YHH1_k127_982211_1 Thymidine kinase K00857 - 2.7.1.21 0.0000000000000000000000000000000000000005717 156.0
YHH1_k127_982211_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000003997 115.0
YHH1_k127_982211_3 - - - - 0.000001967 53.0
YHH1_k127_982211_4 Integrase catalytic - - - 0.00007062 45.0
YHH1_k127_9842297_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000005154 230.0
YHH1_k127_9842297_1 maltose O-acetyltransferase activity K03818 - - 0.0000000000000000000000000000000000003512 146.0
YHH1_k127_9842297_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000003123 97.0
YHH1_k127_9842297_3 Glycosyltransferase Family 4 - - - 0.000000003364 65.0
YHH1_k127_9851883_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 370.0
YHH1_k127_9851883_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 290.0
YHH1_k127_9851883_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000005402 65.0
YHH1_k127_9851883_11 Major facilitator superfamily - - - 0.00007723 49.0
YHH1_k127_9851883_2 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000008179 150.0
YHH1_k127_9851883_3 oligosaccharyl transferase activity - - - 0.00000000000000000000000004165 124.0
YHH1_k127_9851883_4 intein-mediated protein splicing - - - 0.000000000000000000000007372 110.0
YHH1_k127_9851883_5 - - - - 0.00000000000000004771 82.0
YHH1_k127_9851883_6 - - - - 0.0000000000000005609 77.0
YHH1_k127_9851883_7 - - - - 0.00000000000002105 76.0
YHH1_k127_9851883_8 COG NOG14552 non supervised orthologous group - - - 0.000000000002747 70.0
YHH1_k127_9950652_0 Sigma-54 interaction domain K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 325.0
YHH1_k127_9950652_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 317.0
YHH1_k127_9950652_2 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.000000000000000000000000000000000000000000003594 174.0
YHH1_k127_9993900_0 PFAM Fic DOC family - - - 0.00000000000000000000000000000359 132.0
YHH1_k127_9993900_1 Zinc finger, swim domain protein - - - 0.0001112 53.0