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Overview

ID MAG04517
Name YHH2_bin.14
Sample SMP0122
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Beggiatoales
Family Beggiatoaceae
Genus
Species
Assembly information
Completeness (%) 98.56
Contamination (%) 0.36
GC content (%) 43.0
N50 (bp) 47,661
Genome size (bp) 3,436,341

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2735

Gene name Description KEGG GOs EC E-value Score Sequence
YHH2_k127_10348925_0 Peptidase M16C associated K06972 - - 0.0 1098.0
YHH2_k127_10348925_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 604.0
YHH2_k127_10348925_10 ABC transporter, ATP-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 394.0
YHH2_k127_10348925_11 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 400.0
YHH2_k127_10348925_12 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 388.0
YHH2_k127_10348925_13 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 380.0
YHH2_k127_10348925_14 TIGRFAM lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 374.0
YHH2_k127_10348925_15 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 325.0
YHH2_k127_10348925_16 Esterase-like activity of phytase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 310.0
YHH2_k127_10348925_17 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 304.0
YHH2_k127_10348925_18 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001536 289.0
YHH2_k127_10348925_19 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000002207 222.0
YHH2_k127_10348925_2 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 603.0
YHH2_k127_10348925_20 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.000000000000000000000000000000000000000000000000000000000000004223 222.0
YHH2_k127_10348925_21 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000000000000000000001926 207.0
YHH2_k127_10348925_22 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000003709 197.0
YHH2_k127_10348925_23 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000000000000000000000002121 189.0
YHH2_k127_10348925_24 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000000000000000000004469 183.0
YHH2_k127_10348925_26 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000002317 187.0
YHH2_k127_10348925_27 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000003348 115.0
YHH2_k127_10348925_28 - - - - 0.000000000000000000000003009 107.0
YHH2_k127_10348925_29 Small GTP-binding protein - - - 0.000000000000000000000007984 113.0
YHH2_k127_10348925_3 Sodium proton antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 584.0
YHH2_k127_10348925_30 Belongs to the peptidase S8 family - - - 0.00000000000000000002527 91.0
YHH2_k127_10348925_31 STAS domain - - - 0.0000000000000000001053 93.0
YHH2_k127_10348925_32 Periplasmic binding protein K01999 - - 0.0000000000000000008256 103.0
YHH2_k127_10348925_33 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000001999 85.0
YHH2_k127_10348925_35 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000194 46.0
YHH2_k127_10348925_4 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 574.0
YHH2_k127_10348925_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 538.0
YHH2_k127_10348925_6 Heavy metal translocating P-type atpase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 534.0
YHH2_k127_10348925_7 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 510.0
YHH2_k127_10348925_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 505.0
YHH2_k127_10348925_9 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 434.0
YHH2_k127_10438527_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1555.0
YHH2_k127_10438527_1 TIGRFAM amino acid adenylation domain - - - 0.0 1189.0
YHH2_k127_10438527_10 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 389.0
YHH2_k127_10438527_11 endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 412.0
YHH2_k127_10438527_12 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 358.0
YHH2_k127_10438527_13 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 333.0
YHH2_k127_10438527_14 Peptidase M50B-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005073 268.0
YHH2_k127_10438527_15 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000005263 246.0
YHH2_k127_10438527_16 phage Tail Collar - - - 0.00000000000000000000000000000000000000000000000000000000000009617 224.0
YHH2_k127_10438527_17 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000001058 191.0
YHH2_k127_10438527_18 Domain of unknown function DUF29 - - - 0.00000000000000000000000000000000000000000000003423 174.0
YHH2_k127_10438527_19 alginic acid biosynthetic process K07004,K15125,K20276 - - 0.000000000000000004456 101.0
YHH2_k127_10438527_2 malic enzyme K00029 - 1.1.1.40 1.258e-294 922.0
YHH2_k127_10438527_20 Type II transport protein GspH - - - 0.000000000000003763 82.0
YHH2_k127_10438527_21 TIGRFAM conserved repeat domain - - - 0.000003312 54.0
YHH2_k127_10438527_22 TIGRFAM transposase, IS605 OrfB K07496 - - 0.000004037 52.0
YHH2_k127_10438527_3 Citrate transporter - - - 1.128e-239 756.0
YHH2_k127_10438527_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.963e-205 653.0
YHH2_k127_10438527_5 Alpha amylase, catalytic domain K01176,K01236 - 3.2.1.1,3.2.1.141 2.228e-197 632.0
YHH2_k127_10438527_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 9.648e-196 616.0
YHH2_k127_10438527_7 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 596.0
YHH2_k127_10438527_8 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 572.0
YHH2_k127_10438527_9 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 467.0
YHH2_k127_10639521_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1131.0
YHH2_k127_10639521_1 Secretion system protein K02454,K02652 - - 5.841e-269 837.0
YHH2_k127_10639521_10 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000000000000000000000000000004125 192.0
YHH2_k127_10639521_11 - - - - 0.000000000000000000000000000000000000000000000001021 183.0
YHH2_k127_10639521_12 KilA-N - - - 0.000000000000000000000000000000000000000000000001097 184.0
YHH2_k127_10639521_13 Molybdenum cofactor biosynthesis protein MoaE K03635 - 2.8.1.12 0.00000000000000000000000000000000000000009322 155.0
YHH2_k127_10639521_14 cytochrome c5 - - - 0.000000000000000000000002817 110.0
YHH2_k127_10639521_15 - - - - 0.0000000000000000000009769 101.0
YHH2_k127_10639521_16 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000003958 89.0
YHH2_k127_10639521_17 - - - - 0.0000007708 62.0
YHH2_k127_10639521_18 PFAM PKD domain containing protein - - - 0.00006653 57.0
YHH2_k127_10639521_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 572.0
YHH2_k127_10639521_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 475.0
YHH2_k127_10639521_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 424.0
YHH2_k127_10639521_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 411.0
YHH2_k127_10639521_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 407.0
YHH2_k127_10639521_7 short-chain dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 373.0
YHH2_k127_10639521_8 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 337.0
YHH2_k127_10639521_9 PFAM Uncharacterised protein family (UPF0104) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 329.0
YHH2_k127_10706960_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1337.0
YHH2_k127_10706960_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.001e-281 884.0
YHH2_k127_10706960_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000000001173 184.0
YHH2_k127_10706960_11 - - - - 0.000000000000000000000000000000000000000000000000001859 186.0
YHH2_k127_10706960_12 chlorophyll binding - - - 0.0000000000000000000000000000000000000000001986 164.0
YHH2_k127_10706960_13 transcriptional - - - 0.00000000000000000000000000000000000000005581 154.0
YHH2_k127_10706960_14 mRNA cleavage K19158 - - 0.0000000000000000000000000000000003074 134.0
YHH2_k127_10706960_15 - - - - 0.0000000000000000000000000933 115.0
YHH2_k127_10706960_16 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000001684 106.0
YHH2_k127_10706960_17 PFAM plasmid K06218 - - 0.000000000007392 66.0
YHH2_k127_10706960_19 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000008518 51.0
YHH2_k127_10706960_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 5.95e-212 664.0
YHH2_k127_10706960_3 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 457.0
YHH2_k127_10706960_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 444.0
YHH2_k127_10706960_5 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 423.0
YHH2_k127_10706960_6 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 374.0
YHH2_k127_10706960_7 COG0846 NAD-dependent protein deacetylases, SIR2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 304.0
YHH2_k127_10706960_8 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004729 267.0
YHH2_k127_10706960_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004789 226.0
YHH2_k127_10707320_0 COG1960 Acyl-CoA dehydrogenases K20035 - - 1.358e-213 680.0
YHH2_k127_10707320_1 tellurium resistance protein K05792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 530.0
YHH2_k127_10707320_2 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 389.0
YHH2_k127_10707320_3 electron transfer flavoprotein beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 361.0
YHH2_k127_10707320_4 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000000000000001734 204.0
YHH2_k127_10707320_5 PFAM Helix-turn-helix - - - 0.000000000000008271 80.0
YHH2_k127_10707320_6 - - - - 0.0000001517 58.0
YHH2_k127_10707320_8 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.0002356 43.0
YHH2_k127_10754611_0 TIGRFAM amino acid adenylation domain - - - 0.0 1676.0
YHH2_k127_10754611_1 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1345.0
YHH2_k127_10754611_10 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.783e-233 726.0
YHH2_k127_10754611_100 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02655 - - 0.0000000000000000000006079 100.0
YHH2_k127_10754611_101 Membrane fusogenic activity K09806 - - 0.0000000000000000000009762 97.0
YHH2_k127_10754611_102 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05889,K12678 - 1.1.2.6 0.00000000000000000001162 110.0
YHH2_k127_10754611_104 Domain of unknown function (DUF4389) - - - 0.000000000000002702 79.0
YHH2_k127_10754611_105 NTP binding protein (Contains STAS domain) K07122 - - 0.0000000000001102 75.0
YHH2_k127_10754611_106 Type II transport protein GspH K08084 - - 0.000000000005806 74.0
YHH2_k127_10754611_108 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000002297 63.0
YHH2_k127_10754611_109 - - - - 0.00000007443 57.0
YHH2_k127_10754611_11 tRNA binding K04566 - 6.1.1.6 2.925e-230 727.0
YHH2_k127_10754611_110 Sulfotransferase domain - - - 0.0000003099 61.0
YHH2_k127_10754611_112 Las17-binding protein actin regulator - - - 0.000004944 56.0
YHH2_k127_10754611_113 Phospholipase_D-nuclease N-terminal - - - 0.00002618 48.0
YHH2_k127_10754611_115 Zinc-dependent metalloprotease K01406 - 3.4.24.40 0.0001105 57.0
YHH2_k127_10754611_12 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.503e-214 672.0
YHH2_k127_10754611_13 Fungalysin/Thermolysin Propeptide Motif - - - 1.981e-211 713.0
YHH2_k127_10754611_14 Radical SAM superfamily K04069 - 1.97.1.4 1.091e-195 614.0
YHH2_k127_10754611_15 TonB-dependent Receptor Plug K02014 - - 3.996e-194 627.0
YHH2_k127_10754611_16 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 608.0
YHH2_k127_10754611_17 PFAM Transglutaminase-like superfamily K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 611.0
YHH2_k127_10754611_18 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 582.0
YHH2_k127_10754611_19 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 591.0
YHH2_k127_10754611_2 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1322.0
YHH2_k127_10754611_20 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 571.0
YHH2_k127_10754611_21 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 557.0
YHH2_k127_10754611_22 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 552.0
YHH2_k127_10754611_23 DNA repair exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 550.0
YHH2_k127_10754611_24 Tfp pilus assembly protein tip-associated adhesin PilY1 K02674 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 577.0
YHH2_k127_10754611_25 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 515.0
YHH2_k127_10754611_26 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 510.0
YHH2_k127_10754611_27 actin actin family protein K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 504.0
YHH2_k127_10754611_28 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 505.0
YHH2_k127_10754611_29 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 503.0
YHH2_k127_10754611_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1167.0
YHH2_k127_10754611_30 COG0714 MoxR-like ATPases K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 481.0
YHH2_k127_10754611_31 DNA methylase K07319 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 481.0
YHH2_k127_10754611_32 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 476.0
YHH2_k127_10754611_33 PFAM Archaeal ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 491.0
YHH2_k127_10754611_34 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 459.0
YHH2_k127_10754611_35 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 478.0
YHH2_k127_10754611_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 443.0
YHH2_k127_10754611_37 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 440.0
YHH2_k127_10754611_38 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 437.0
YHH2_k127_10754611_39 acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 443.0
YHH2_k127_10754611_4 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 8.554e-316 979.0
YHH2_k127_10754611_40 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 415.0
YHH2_k127_10754611_41 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 404.0
YHH2_k127_10754611_42 ankyrin repeat K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 415.0
YHH2_k127_10754611_43 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 408.0
YHH2_k127_10754611_44 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 394.0
YHH2_k127_10754611_45 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 372.0
YHH2_k127_10754611_46 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 371.0
YHH2_k127_10754611_47 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 366.0
YHH2_k127_10754611_48 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 356.0
YHH2_k127_10754611_49 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 355.0
YHH2_k127_10754611_5 carbamoyl transferase, NodU family K00612 - - 4.54e-308 954.0
YHH2_k127_10754611_50 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 347.0
YHH2_k127_10754611_51 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 317.0
YHH2_k127_10754611_52 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 319.0
YHH2_k127_10754611_53 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 317.0
YHH2_k127_10754611_54 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 299.0
YHH2_k127_10754611_55 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 288.0
YHH2_k127_10754611_56 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002632 283.0
YHH2_k127_10754611_58 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003743 276.0
YHH2_k127_10754611_59 Vancomycin high temperature exclusion protein K03748 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0042221,GO:0042493,GO:0044425,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000011 272.0
YHH2_k127_10754611_6 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 6.971e-243 760.0
YHH2_k127_10754611_60 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006935 271.0
YHH2_k127_10754611_61 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007352 269.0
YHH2_k127_10754611_62 PFAM Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000625 265.0
YHH2_k127_10754611_63 TIGRFAM nudix-type nucleoside diphosphatase, YffH AdpP family K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001026 260.0
YHH2_k127_10754611_64 acid phosphatase activity K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 264.0
YHH2_k127_10754611_65 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001096 249.0
YHH2_k127_10754611_66 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000003001 236.0
YHH2_k127_10754611_67 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000000000008069 233.0
YHH2_k127_10754611_68 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000008578 236.0
YHH2_k127_10754611_69 Thiol disulfide interchange protein K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000001651 228.0
YHH2_k127_10754611_7 magnesium chelatase K07391 - - 4.479e-236 738.0
YHH2_k127_10754611_70 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
YHH2_k127_10754611_71 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000002571 221.0
YHH2_k127_10754611_72 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000001277 207.0
YHH2_k127_10754611_73 Putative member of DMT superfamily (DUF486) K09922 - - 0.000000000000000000000000000000000000000000000000000000001719 202.0
YHH2_k127_10754611_74 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000005584 201.0
YHH2_k127_10754611_76 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.00000000000000000000000000000000000000000000000000000009717 207.0
YHH2_k127_10754611_77 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000001403 199.0
YHH2_k127_10754611_78 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000004382 185.0
YHH2_k127_10754611_79 Pfam Rhodanese-like - - - 0.00000000000000000000000000000000000000000000000001418 183.0
YHH2_k127_10754611_8 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 8.439e-236 737.0
YHH2_k127_10754611_80 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000001418 183.0
YHH2_k127_10754611_81 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000000000000003843 177.0
YHH2_k127_10754611_82 Subtilase family - - - 0.000000000000000000000000000000000000000000000199 191.0
YHH2_k127_10754611_83 Thiamine-binding protein - - - 0.000000000000000000000000000000000000000000002005 166.0
YHH2_k127_10754611_84 pilus assembly protein PilW K02672 - - 0.000000000000000000000000000000000000000009632 167.0
YHH2_k127_10754611_85 - - - - 0.0000000000000000000000000000000000000002146 166.0
YHH2_k127_10754611_86 COGs COG3039 Transposase and inactivated derivatives IS5 family K07481 - - 0.0000000000000000000000000000000000000003406 152.0
YHH2_k127_10754611_87 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000003529 151.0
YHH2_k127_10754611_88 - - - - 0.0000000000000000000000000000000000000354 145.0
YHH2_k127_10754611_89 RDD family - - - 0.00000000000000000000000000000000001862 140.0
YHH2_k127_10754611_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.367e-233 730.0
YHH2_k127_10754611_90 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000005477 134.0
YHH2_k127_10754611_91 OsmC-like protein - - - 0.0000000000000000000000000000000003592 136.0
YHH2_k127_10754611_92 of membrane protease K07340 - - 0.0000000000000000000000000000000009077 135.0
YHH2_k127_10754611_94 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000364 145.0
YHH2_k127_10754611_95 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000281 145.0
YHH2_k127_10754611_96 Putative Ig domain - - - 0.0000000000000000000000000000004586 144.0
YHH2_k127_10754611_97 - - - - 0.000000000000000000000000000003412 124.0
YHH2_k127_10754611_98 subunit of a heme lyase K02200 - - 0.0000000000000000000000000006685 119.0
YHH2_k127_10754611_99 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000006099 114.0
YHH2_k127_10966768_0 peptidase M1 K01256 - 3.4.11.2 7.729e-216 676.0
YHH2_k127_10966768_1 NADH flavin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 514.0
YHH2_k127_11128956_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1543.0
YHH2_k127_11128956_1 2-oxoglutarate dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1341.0
YHH2_k127_11128956_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 583.0
YHH2_k127_11128956_11 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 575.0
YHH2_k127_11128956_12 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 557.0
YHH2_k127_11128956_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 539.0
YHH2_k127_11128956_14 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 568.0
YHH2_k127_11128956_15 COG1613 ABC-type sulfate transport system, periplasmic component K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 504.0
YHH2_k127_11128956_16 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 484.0
YHH2_k127_11128956_17 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 473.0
YHH2_k127_11128956_18 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 445.0
YHH2_k127_11128956_19 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 441.0
YHH2_k127_11128956_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1063.0
YHH2_k127_11128956_20 PFAM binding-protein-dependent transport systems inner membrane component K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 422.0
YHH2_k127_11128956_21 Squalene phytoene synthase K00801 - 2.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 424.0
YHH2_k127_11128956_22 TIGRFAM sulfate ABC transporter, inner membrane subunit CysW K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 413.0
YHH2_k127_11128956_23 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 410.0
YHH2_k127_11128956_24 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 389.0
YHH2_k127_11128956_25 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 381.0
YHH2_k127_11128956_26 Pfam OmpA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 359.0
YHH2_k127_11128956_27 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 344.0
YHH2_k127_11128956_28 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 327.0
YHH2_k127_11128956_29 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009355 324.0
YHH2_k127_11128956_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.114e-242 760.0
YHH2_k127_11128956_30 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 319.0
YHH2_k127_11128956_31 Glycosyltransferases K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 321.0
YHH2_k127_11128956_32 Protein of unknown function (DUF3782) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 289.0
YHH2_k127_11128956_33 Glycosyl transferase, family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001432 283.0
YHH2_k127_11128956_34 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000001817 267.0
YHH2_k127_11128956_35 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002819 261.0
YHH2_k127_11128956_36 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002391 248.0
YHH2_k127_11128956_37 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
YHH2_k127_11128956_38 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001668 233.0
YHH2_k127_11128956_39 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001767 237.0
YHH2_k127_11128956_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.19e-218 683.0
YHH2_k127_11128956_40 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004528 243.0
YHH2_k127_11128956_41 Sugar (and other) transporter K02445,K07783 - - 0.000000000000000000000000000000000000000000000000000000000000000000746 244.0
YHH2_k127_11128956_42 PFAM cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000001311 210.0
YHH2_k127_11128956_43 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000029 208.0
YHH2_k127_11128956_44 PFAM Smr - - - 0.0000000000000000000000000000000000000000000000000000001465 199.0
YHH2_k127_11128956_45 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000000000001219 197.0
YHH2_k127_11128956_46 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000002452 188.0
YHH2_k127_11128956_47 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000000000000000000003057 184.0
YHH2_k127_11128956_48 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000000000000000000004805 184.0
YHH2_k127_11128956_49 protein serine/threonine phosphatase activity - - - 0.000000000000000000000000000000000000004749 155.0
YHH2_k127_11128956_5 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.917e-196 624.0
YHH2_k127_11128956_51 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000007981 136.0
YHH2_k127_11128956_52 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000002919 126.0
YHH2_k127_11128956_53 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000009699 134.0
YHH2_k127_11128956_54 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000001411 119.0
YHH2_k127_11128956_55 AntA/AntB antirepressor K07741 - - 0.0000000000000000000000000007478 124.0
YHH2_k127_11128956_56 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.00000000000000000000000002155 110.0
YHH2_k127_11128956_58 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000000000000000004045 108.0
YHH2_k127_11128956_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.263e-195 616.0
YHH2_k127_11128956_61 Sulphur globule protein - - - 0.0000000000000001869 85.0
YHH2_k127_11128956_62 LppC putative lipoprotein - - - 0.00000000103 61.0
YHH2_k127_11128956_63 Type II IV secretion system protein K02652 - - 0.000000001415 61.0
YHH2_k127_11128956_65 - - - - 0.0000005349 59.0
YHH2_k127_11128956_66 Glycosyl transferases group 1 - - - 0.00001497 53.0
YHH2_k127_11128956_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 577.0
YHH2_k127_11128956_8 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 599.0
YHH2_k127_11128956_9 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 590.0
YHH2_k127_11375056_0 Glycosyl hydrolase family 57 - - - 2.307e-250 779.0
YHH2_k127_11375056_1 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 9.177e-244 760.0
YHH2_k127_11375056_10 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 319.0
YHH2_k127_11375056_11 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 297.0
YHH2_k127_11375056_12 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000003427 245.0
YHH2_k127_11375056_14 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000197 232.0
YHH2_k127_11375056_15 - - - - 0.0000000000000000000000005788 113.0
YHH2_k127_11375056_16 - - - - 0.0000000000000001901 86.0
YHH2_k127_11375056_18 - - - - 0.0000000001697 65.0
YHH2_k127_11375056_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.179e-227 712.0
YHH2_k127_11375056_3 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 2.928e-207 653.0
YHH2_k127_11375056_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 515.0
YHH2_k127_11375056_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 475.0
YHH2_k127_11375056_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 445.0
YHH2_k127_11375056_7 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 425.0
YHH2_k127_11375056_8 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 387.0
YHH2_k127_11375056_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 392.0
YHH2_k127_11379274_0 ABC-type oligopeptide transport system, periplasmic component K02035,K13893 GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042597,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 2.107e-245 771.0
YHH2_k127_11379274_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 4.556e-213 683.0
YHH2_k127_11379274_10 PFAM mce related protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 390.0
YHH2_k127_11379274_11 serine-type endopeptidase activity K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 391.0
YHH2_k127_11379274_12 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 370.0
YHH2_k127_11379274_13 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 354.0
YHH2_k127_11379274_14 FabA-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 299.0
YHH2_k127_11379274_15 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 304.0
YHH2_k127_11379274_16 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000338 258.0
YHH2_k127_11379274_17 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000006222 237.0
YHH2_k127_11379274_18 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000002619 235.0
YHH2_k127_11379274_19 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000001206 236.0
YHH2_k127_11379274_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.908e-200 644.0
YHH2_k127_11379274_20 phosphoribosyltransferase K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000009422 220.0
YHH2_k127_11379274_21 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000005511 214.0
YHH2_k127_11379274_22 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000001192 217.0
YHH2_k127_11379274_23 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000002798 227.0
YHH2_k127_11379274_24 - - - - 0.00000000000000000000000000000000000000000000000000000004079 200.0
YHH2_k127_11379274_25 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000009007 188.0
YHH2_k127_11379274_26 Domain of unknown function (DUF4401) - - - 0.0000000000000000000000000000000000000000000000000001813 199.0
YHH2_k127_11379274_27 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K05568 - - 0.0000000000000000000000000000000000000000000000003736 194.0
YHH2_k127_11379274_28 PTS system fructose IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000002106 176.0
YHH2_k127_11379274_29 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000008723 159.0
YHH2_k127_11379274_3 Response regulator receiver K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 529.0
YHH2_k127_11379274_30 response regulator - - - 0.00000000000000000000000000000000004583 140.0
YHH2_k127_11379274_31 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000316 136.0
YHH2_k127_11379274_32 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000105 121.0
YHH2_k127_11379274_33 addiction module antidote protein, HigA family K21498 - - 0.000000000000000000000000001648 114.0
YHH2_k127_11379274_34 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 GO:0008150,GO:0009405,GO:0044419,GO:0051704 - 0.00000000000000000000002925 105.0
YHH2_k127_11379274_35 GHKL domain - - - 0.0000000000000000000002253 100.0
YHH2_k127_11379274_36 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000001061 98.0
YHH2_k127_11379274_37 cyclic nucleotide binding K04739,K10914 - - 0.00000000000001236 89.0
YHH2_k127_11379274_38 cyclic nucleotide binding K00384,K04739,K07001,K10914 - 1.8.1.9 0.0000000000003338 84.0
YHH2_k127_11379274_39 Transposase DDE domain - - - 0.000000001551 61.0
YHH2_k127_11379274_4 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 529.0
YHH2_k127_11379274_41 COG3209 Rhs family protein - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.000000004415 66.0
YHH2_k127_11379274_42 COG0675 Transposase and inactivated derivatives K07496 - - 0.00002869 48.0
YHH2_k127_11379274_5 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 496.0
YHH2_k127_11379274_6 ABC-type branched-chain amino acid transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 518.0
YHH2_k127_11379274_7 ABC-type branched-chain amino acid transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 512.0
YHH2_k127_11379274_8 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 437.0
YHH2_k127_11379274_9 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
YHH2_k127_11427142_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1665.0
YHH2_k127_11427142_1 AAA ATPase domain - - - 0.0 1587.0
YHH2_k127_11427142_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 613.0
YHH2_k127_11427142_12 associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 565.0
YHH2_k127_11427142_13 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 540.0
YHH2_k127_11427142_14 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 517.0
YHH2_k127_11427142_15 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 516.0
YHH2_k127_11427142_16 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 493.0
YHH2_k127_11427142_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 482.0
YHH2_k127_11427142_18 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 433.0
YHH2_k127_11427142_19 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 434.0
YHH2_k127_11427142_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1437.0
YHH2_k127_11427142_20 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 427.0
YHH2_k127_11427142_21 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 402.0
YHH2_k127_11427142_22 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 379.0
YHH2_k127_11427142_23 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 383.0
YHH2_k127_11427142_24 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 352.0
YHH2_k127_11427142_25 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 340.0
YHH2_k127_11427142_26 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 361.0
YHH2_k127_11427142_27 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 308.0
YHH2_k127_11427142_28 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 319.0
YHH2_k127_11427142_29 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004747 274.0
YHH2_k127_11427142_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0 1301.0
YHH2_k127_11427142_30 Protein of unknown function (DUF4435) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003481 259.0
YHH2_k127_11427142_31 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007704 242.0
YHH2_k127_11427142_32 - - - - 0.00000000000000000000000000000000000000000000000000001758 204.0
YHH2_k127_11427142_33 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000000000000000000000000000000000000000000000002244 205.0
YHH2_k127_11427142_34 LysM domain K01448,K08307,K19223,K22278 - 3.5.1.104,3.5.1.28 0.000000000000000000000000000000000000000000000000003001 196.0
YHH2_k127_11427142_35 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000001911 186.0
YHH2_k127_11427142_36 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000004132 170.0
YHH2_k127_11427142_37 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000792 170.0
YHH2_k127_11427142_38 Peptidase family M23 K06194 - - 0.000000000000000000000000000000000000000000005636 173.0
YHH2_k127_11427142_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1071.0
YHH2_k127_11427142_40 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000001038 160.0
YHH2_k127_11427142_42 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000001143 144.0
YHH2_k127_11427142_43 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000007607 135.0
YHH2_k127_11427142_44 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02487,K06596 - - 0.00000000000000000000000000000004424 146.0
YHH2_k127_11427142_45 Peptidase family M48 - - - 0.000000000000000000000000000007217 130.0
YHH2_k127_11427142_46 Iron-sulphur cluster assembly - - - 0.00000000000000000000000007054 107.0
YHH2_k127_11427142_49 - - - - 0.00000000000000003476 90.0
YHH2_k127_11427142_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.53e-301 930.0
YHH2_k127_11427142_50 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000482 89.0
YHH2_k127_11427142_51 Histidine kinase - - - 0.0000000000000003216 82.0
YHH2_k127_11427142_52 Cold shock protein domain K03704 - - 0.0000000001067 67.0
YHH2_k127_11427142_53 membrane K06194 - - 0.00000003088 60.0
YHH2_k127_11427142_6 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.866e-290 919.0
YHH2_k127_11427142_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.572e-279 865.0
YHH2_k127_11427142_8 Glycosyl hydrolase family 57 - - - 1.24e-253 800.0
YHH2_k127_11427142_9 Participates in both transcription termination and antitermination K02600 - - 5.627e-209 660.0
YHH2_k127_11682107_0 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 591.0
YHH2_k127_11682107_1 cheY-homologous receiver domain K20977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 547.0
YHH2_k127_11682107_10 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 329.0
YHH2_k127_11682107_11 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 319.0
YHH2_k127_11682107_12 PFAM PfkB domain protein K00846 - 2.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 301.0
YHH2_k127_11682107_13 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 287.0
YHH2_k127_11682107_14 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 284.0
YHH2_k127_11682107_15 PFAM Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003595 258.0
YHH2_k127_11682107_16 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000001261 198.0
YHH2_k127_11682107_17 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000000000000000000000000000007415 185.0
YHH2_k127_11682107_18 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000506 183.0
YHH2_k127_11682107_19 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000000000006037 136.0
YHH2_k127_11682107_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 460.0
YHH2_k127_11682107_20 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000000001943 133.0
YHH2_k127_11682107_21 Domain of unknown function (DUF4258) - - - 0.0000000000000000000000000000000002674 134.0
YHH2_k127_11682107_22 Regulatory protein, FmdB family - - - 0.0000000000000000000000002842 107.0
YHH2_k127_11682107_23 PIN domain - - - 0.000000000000000000000001984 107.0
YHH2_k127_11682107_24 TIGRFAM YgiT-type zinc finger domain - - - 0.000000000000000000005701 93.0
YHH2_k127_11682107_25 - - - - 0.0000000000000001358 83.0
YHH2_k127_11682107_26 Protein of unknown function (DUF3096) - - - 0.0000000000517 64.0
YHH2_k127_11682107_27 Addiction module toxin, RelE StbE family - - - 0.00000001265 57.0
YHH2_k127_11682107_28 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00001443 53.0
YHH2_k127_11682107_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 441.0
YHH2_k127_11682107_4 heptosyltransferase K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 401.0
YHH2_k127_11682107_5 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 385.0
YHH2_k127_11682107_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 370.0
YHH2_k127_11682107_7 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 364.0
YHH2_k127_11682107_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 323.0
YHH2_k127_11682107_9 Protein of unknown function (DUF3050) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
YHH2_k127_1408232_0 N-6 DNA Methylase - - - 0.0 1106.0
YHH2_k127_1408232_1 protein conserved in bacteria - - - 9.847e-277 869.0
YHH2_k127_1408232_10 response regulator K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 392.0
YHH2_k127_1408232_11 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 388.0
YHH2_k127_1408232_12 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 363.0
YHH2_k127_1408232_13 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 301.0
YHH2_k127_1408232_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004476 259.0
YHH2_k127_1408232_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001936 261.0
YHH2_k127_1408232_16 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002892 239.0
YHH2_k127_1408232_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000004654 155.0
YHH2_k127_1408232_18 Bacterial toxin of type II toxin-antitoxin system, YafQ - - - 0.000000000000000000000003385 104.0
YHH2_k127_1408232_19 cytochrome K08738 - - 0.000000000000000000007847 97.0
YHH2_k127_1408232_2 CHAT domain - - - 9.426e-218 703.0
YHH2_k127_1408232_21 RelB antitoxin K07473 - - 0.000000003769 61.0
YHH2_k127_1408232_22 Protein of unknown function DUF262 - - - 0.0000001886 55.0
YHH2_k127_1408232_23 - - - - 0.00003119 51.0
YHH2_k127_1408232_24 - - - - 0.0006667 44.0
YHH2_k127_1408232_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.978e-211 690.0
YHH2_k127_1408232_4 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 559.0
YHH2_k127_1408232_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 537.0
YHH2_k127_1408232_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 581.0
YHH2_k127_1408232_7 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 508.0
YHH2_k127_1408232_8 Sigma-70 factor, region 1.2 K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 417.0
YHH2_k127_1408232_9 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 417.0
YHH2_k127_1426517_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 397.0
YHH2_k127_1426517_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.0000000000000000000000000000000221 140.0
YHH2_k127_1426517_2 type II and III secretion system protein K02453 - - 0.000000000003383 78.0
YHH2_k127_1449660_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 584.0
YHH2_k127_1449660_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 601.0
YHH2_k127_1449660_10 Outer membrane efflux protein - - - 0.000000000000000000000000009781 126.0
YHH2_k127_1449660_11 Methionine biosynthesis protein MetW - - - 0.00000000000003378 76.0
YHH2_k127_1449660_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 587.0
YHH2_k127_1449660_3 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 484.0
YHH2_k127_1449660_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 477.0
YHH2_k127_1449660_5 ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 506.0
YHH2_k127_1449660_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 327.0
YHH2_k127_1449660_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000557 271.0
YHH2_k127_1449660_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000007636 256.0
YHH2_k127_1449660_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000003301 170.0
YHH2_k127_147365_0 Type II and III secretion system protein K02453 - - 2.508e-223 711.0
YHH2_k127_147365_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 559.0
YHH2_k127_147365_10 - - - - 0.0000001547 53.0
YHH2_k127_147365_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 493.0
YHH2_k127_147365_3 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 332.0
YHH2_k127_147365_4 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 284.0
YHH2_k127_147365_5 COG1214 Inactive homolog of metal-dependent proteases K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000001754 227.0
YHH2_k127_147365_6 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000000009459 137.0
YHH2_k127_147365_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000008646 123.0
YHH2_k127_147365_8 ThiS family K03154 - - 0.00000000000000008583 81.0
YHH2_k127_147365_9 TolA C-terminal K03646 - - 0.0000000000003275 80.0
YHH2_k127_1634049_0 COG0608 Single-stranded DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 595.0
YHH2_k127_1634049_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000001107 172.0
YHH2_k127_1634049_2 HsdM N-terminal domain K03427 - 2.1.1.72 0.000000000000000000000000000000000000003042 153.0
YHH2_k127_1634049_3 guanyl-nucleotide exchange factor activity K01387,K07114,K12287 - 3.4.24.3 0.000000000000000000000000001774 131.0
YHH2_k127_1634049_4 AntA/AntB antirepressor K07741 - - 0.000000000000000000000001618 113.0
YHH2_k127_1634049_5 Transposase, IS605 OrfB family K07496 - - 0.00000000000001271 73.0
YHH2_k127_1634049_6 - - - - 0.000004406 51.0
YHH2_k127_1637649_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1199.0
YHH2_k127_1637649_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.681e-305 945.0
YHH2_k127_1637649_10 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 456.0
YHH2_k127_1637649_11 Cache domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 473.0
YHH2_k127_1637649_12 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 454.0
YHH2_k127_1637649_13 Glycosyl transferases group 1 K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 444.0
YHH2_k127_1637649_14 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 460.0
YHH2_k127_1637649_15 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 424.0
YHH2_k127_1637649_16 serine-type endopeptidase activity K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 426.0
YHH2_k127_1637649_17 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 411.0
YHH2_k127_1637649_18 Transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 406.0
YHH2_k127_1637649_19 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 392.0
YHH2_k127_1637649_2 Putative diguanylate phosphodiesterase - - - 2.323e-240 756.0
YHH2_k127_1637649_20 protein conserved in bacteria (DUF2333) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 389.0
YHH2_k127_1637649_21 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 383.0
YHH2_k127_1637649_22 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 375.0
YHH2_k127_1637649_23 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 361.0
YHH2_k127_1637649_24 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 358.0
YHH2_k127_1637649_25 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 348.0
YHH2_k127_1637649_26 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 336.0
YHH2_k127_1637649_27 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 305.0
YHH2_k127_1637649_28 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 290.0
YHH2_k127_1637649_29 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000139 296.0
YHH2_k127_1637649_3 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 4.449e-231 745.0
YHH2_k127_1637649_30 Putative DNA-binding domain K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001998 259.0
YHH2_k127_1637649_31 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000001253 231.0
YHH2_k127_1637649_32 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000001755 226.0
YHH2_k127_1637649_33 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000001115 217.0
YHH2_k127_1637649_34 Belongs to the Dps family K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000003306 211.0
YHH2_k127_1637649_35 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000006258 210.0
YHH2_k127_1637649_36 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000007896 215.0
YHH2_k127_1637649_37 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000003116 206.0
YHH2_k127_1637649_38 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000001052 204.0
YHH2_k127_1637649_39 GGDEF domain K07814 - - 0.00000000000000000000000000000000000000000000000000007837 188.0
YHH2_k127_1637649_4 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 1.127e-219 708.0
YHH2_k127_1637649_40 Transferase hexapeptide repeat K03818 - - 0.00000000000000000000000000000000000000000000000001548 186.0
YHH2_k127_1637649_41 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000006374 189.0
YHH2_k127_1637649_42 PFAM Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000005329 172.0
YHH2_k127_1637649_43 - - - - 0.000000000000000000000000000000000001845 154.0
YHH2_k127_1637649_44 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000001618 138.0
YHH2_k127_1637649_45 PFAM Pilus assembly protein PilP K02665 - - 0.00000000000000000000000000000008902 131.0
YHH2_k127_1637649_46 SdrD B-like domain - - - 0.000000000000000000000000000003323 139.0
YHH2_k127_1637649_47 PFAM Peptidase S24 S26A S26B, conserved region - - - 0.000000000000000000000000002595 113.0
YHH2_k127_1637649_48 membrane - - - 0.000000000000000000001659 97.0
YHH2_k127_1637649_49 Putative phage abortive infection protein - - - 0.00000000000000000327 95.0
YHH2_k127_1637649_5 TIGRFAM type IV pilus secretin (or competence protein) PilQ K02666 - - 5.37e-219 701.0
YHH2_k127_1637649_50 acetyltransferase, isoleucine patch superfamily K03818 - - 0.00000000000000001879 85.0
YHH2_k127_1637649_51 Competence protein ComEA K02237 - - 0.00000000000002243 78.0
YHH2_k127_1637649_52 - - - - 0.00000000000003326 85.0
YHH2_k127_1637649_53 Helix-turn-helix domain K07496 - - 0.00000000002393 64.0
YHH2_k127_1637649_54 - - - - 0.0000001311 58.0
YHH2_k127_1637649_6 AAA-ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 619.0
YHH2_k127_1637649_7 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 566.0
YHH2_k127_1637649_8 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 554.0
YHH2_k127_1637649_9 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009325 490.0
YHH2_k127_1637831_0 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000001356 164.0
YHH2_k127_1637831_1 KilA-N - - - 0.000000000000000000000000000000000000000002456 169.0
YHH2_k127_1637831_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000001001 121.0
YHH2_k127_1637831_3 PFAM Helix-turn-helix - - - 0.00000000000000000000001979 105.0
YHH2_k127_1637831_4 ORF6C domain - - - 0.0000000000000000000002953 109.0
YHH2_k127_1637831_5 PFAM BRO, N-terminal - - - 0.000000000002728 78.0
YHH2_k127_1650495_0 PFAM MoeZ MoeB domain K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 298.0
YHH2_k127_1650495_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001386 259.0
YHH2_k127_1650495_2 PFAM O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000002054 217.0
YHH2_k127_1650495_3 Competence protein - - - 0.0000000000000000000000000000000000000000000000000000001233 202.0
YHH2_k127_1915688_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1055.0
YHH2_k127_1915688_1 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K07516 - 1.1.1.35 7.286e-309 966.0
YHH2_k127_1915688_10 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 336.0
YHH2_k127_1915688_11 domain, Protein K03112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 312.0
YHH2_k127_1915688_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001935 265.0
YHH2_k127_1915688_13 Large exoproteins involved in heme utilization or adhesion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002886 284.0
YHH2_k127_1915688_14 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000002626 243.0
YHH2_k127_1915688_15 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000001386 231.0
YHH2_k127_1915688_16 Pfam ABC - - - 0.000000000000000000000000000000000000000000000000000000000335 211.0
YHH2_k127_1915688_17 membrane - - - 0.0000000000000000000000000000003208 124.0
YHH2_k127_1915688_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000008336 111.0
YHH2_k127_1915688_19 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000004449 94.0
YHH2_k127_1915688_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.02e-257 803.0
YHH2_k127_1915688_20 Putative restriction endonuclease - - - 0.0000000000000000001984 94.0
YHH2_k127_1915688_21 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000006171 88.0
YHH2_k127_1915688_22 transferase activity, transferring glycosyl groups - - - 0.000000000000142 85.0
YHH2_k127_1915688_23 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000003353 60.0
YHH2_k127_1915688_24 Glycosyl Transferase K07011 - - 0.000000007412 60.0
YHH2_k127_1915688_25 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0007844 42.0
YHH2_k127_1915688_3 N-4 methylation of cytosine K00590 - 2.1.1.113 1.287e-226 713.0
YHH2_k127_1915688_4 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 564.0
YHH2_k127_1915688_5 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 522.0
YHH2_k127_1915688_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 512.0
YHH2_k127_1915688_7 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 415.0
YHH2_k127_1915688_8 Restriction endonuclease K01155 - 3.1.21.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 353.0
YHH2_k127_1915688_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 342.0
YHH2_k127_2047964_0 Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 6.773e-256 807.0
YHH2_k127_2047964_1 PFAM Ig domain protein, group 1 domain protein - - - 3.303e-251 816.0
YHH2_k127_2047964_10 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 453.0
YHH2_k127_2047964_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 452.0
YHH2_k127_2047964_12 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 446.0
YHH2_k127_2047964_13 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 421.0
YHH2_k127_2047964_14 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 416.0
YHH2_k127_2047964_15 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 411.0
YHH2_k127_2047964_16 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 353.0
YHH2_k127_2047964_17 sterol desaturase K00227 - 1.14.19.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 288.0
YHH2_k127_2047964_18 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003314 267.0
YHH2_k127_2047964_19 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000169 277.0
YHH2_k127_2047964_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 2.565e-217 687.0
YHH2_k127_2047964_20 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 269.0
YHH2_k127_2047964_21 ADP-Ribose Pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004142 239.0
YHH2_k127_2047964_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000006507 227.0
YHH2_k127_2047964_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000005556 224.0
YHH2_k127_2047964_24 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000003719 196.0
YHH2_k127_2047964_25 - - - - 0.000000000000000000000000000000000000000000000000000006619 201.0
YHH2_k127_2047964_26 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000004388 188.0
YHH2_k127_2047964_27 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000008241 188.0
YHH2_k127_2047964_28 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000006052 185.0
YHH2_k127_2047964_29 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000006987 173.0
YHH2_k127_2047964_3 PFAM tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 2.022e-212 665.0
YHH2_k127_2047964_30 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000005968 170.0
YHH2_k127_2047964_31 cytochrome K17230 - - 0.000000000000000000000000000000000000000000006148 169.0
YHH2_k127_2047964_32 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000000000000000000000000000000000000003419 161.0
YHH2_k127_2047964_33 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000001413 145.0
YHH2_k127_2047964_34 COG0589 Universal stress protein UspA and related K14055 - - 0.0000000000000000000000000000002226 135.0
YHH2_k127_2047964_35 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.0000000000000000000000000006551 117.0
YHH2_k127_2047964_36 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000008862 89.0
YHH2_k127_2047964_37 COGs COG5439 conserved - - - 0.00000000000000000009652 93.0
YHH2_k127_2047964_38 - - - - 0.000000000000002053 82.0
YHH2_k127_2047964_39 - - - - 0.0000000000001899 76.0
YHH2_k127_2047964_4 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 1.79e-208 657.0
YHH2_k127_2047964_40 Bacterial pre-peptidase C-terminal domain - - - 0.000000000000271 81.0
YHH2_k127_2047964_41 cell wall binding repeat - - - 0.00000000006427 76.0
YHH2_k127_2047964_42 Transcriptional regulator, AraC family - - - 0.000004442 53.0
YHH2_k127_2047964_43 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0006343 43.0
YHH2_k127_2047964_5 ATPase associated with various cellular activities, AAA_5 K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 601.0
YHH2_k127_2047964_6 UDP-galactopyranose mutase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 565.0
YHH2_k127_2047964_7 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17229 - 1.8.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 547.0
YHH2_k127_2047964_8 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 492.0
YHH2_k127_2047964_9 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 450.0
YHH2_k127_2053874_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1694.0
YHH2_k127_2053874_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 454.0
YHH2_k127_2053874_2 COG1943 Transposase and inactivated derivatives K07491 - - 0.0002298 44.0
YHH2_k127_2308832_0 guanyl-nucleotide exchange factor activity K12287 - - 0.0 1078.0
YHH2_k127_2308832_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1027.0
YHH2_k127_2308832_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 491.0
YHH2_k127_2308832_11 Thiazole biosynthesis protein ThiG K02371 - 1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 442.0
YHH2_k127_2308832_12 GTP1/OBG K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 443.0
YHH2_k127_2308832_13 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 404.0
YHH2_k127_2308832_14 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 399.0
YHH2_k127_2308832_15 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 355.0
YHH2_k127_2308832_16 TonB-dependent Receptor Plug Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 346.0
YHH2_k127_2308832_17 Regulator of chromosome condensation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 316.0
YHH2_k127_2308832_18 PfkB domain protein K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 297.0
YHH2_k127_2308832_19 LytTr DNA-binding domain K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
YHH2_k127_2308832_2 sucrose synthase K00695 - 2.4.1.13 0.0 1015.0
YHH2_k127_2308832_20 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000005949 256.0
YHH2_k127_2308832_21 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000000000000000003021 222.0
YHH2_k127_2308832_22 CHAT domain K03496,K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000001661 216.0
YHH2_k127_2308832_23 glyoxalase K08234 - - 0.0000000000000000000000000000000000000000000000000000004671 198.0
YHH2_k127_2308832_24 PFAM CYTH domain - - - 0.000000000000000000000000000000000000000000000000000001759 197.0
YHH2_k127_2308832_26 Pfam Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000003361 199.0
YHH2_k127_2308832_27 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000398 171.0
YHH2_k127_2308832_28 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000000000000752 155.0
YHH2_k127_2308832_29 Histidine kinase - - - 0.00000000000000000000000000000000000005073 146.0
YHH2_k127_2308832_3 glycosyl transferase group 1 K00696 - 2.4.1.14 2.909e-270 850.0
YHH2_k127_2308832_30 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000002447 130.0
YHH2_k127_2308832_31 Pfam HNH endonuclease - - - 0.00000000000000000000000000000005569 128.0
YHH2_k127_2308832_32 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000007505 119.0
YHH2_k127_2308832_33 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000142 115.0
YHH2_k127_2308832_35 - - - - 0.00000000000000000000001575 102.0
YHH2_k127_2308832_36 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.00000000000000000000009138 106.0
YHH2_k127_2308832_37 COG0739 Membrane proteins related to metalloendopeptidases K21472 - - 0.00000000000000000001098 93.0
YHH2_k127_2308832_38 Protein of unknown function (DUF2505) - - - 0.0000000000000000000747 95.0
YHH2_k127_2308832_39 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 - - 0.0000000000000000000758 90.0
YHH2_k127_2308832_4 Protein of unknown function, DUF255 K06888 - - 2.2e-266 837.0
YHH2_k127_2308832_40 PIN domain - - - 0.000000000003152 71.0
YHH2_k127_2308832_42 Bacterial antitoxin of type II TA system, VapB - - - 0.00000002586 57.0
YHH2_k127_2308832_43 COGs COG3039 Transposase and inactivated derivatives IS5 family K07481 - - 0.0000001994 54.0
YHH2_k127_2308832_44 - - - - 0.000003876 52.0
YHH2_k127_2308832_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.102e-248 774.0
YHH2_k127_2308832_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.841e-214 674.0
YHH2_k127_2308832_7 Type II and III secretion system protein - - - 1.899e-209 674.0
YHH2_k127_2308832_8 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 595.0
YHH2_k127_2308832_9 endonuclease activity K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 521.0
YHH2_k127_2319991_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.691e-300 930.0
YHH2_k127_2319991_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.655e-242 756.0
YHH2_k127_2319991_12 BrnA antitoxin of type II toxin-antitoxin system - - - 0.0007487 45.0
YHH2_k127_2319991_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 621.0
YHH2_k127_2319991_3 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 554.0
YHH2_k127_2319991_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 476.0
YHH2_k127_2319991_5 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 296.0
YHH2_k127_2319991_6 Iron--sulfur cluster insertion protein erpA K15724 - - 0.000000000000000000000000000000000000000000000000002075 184.0
YHH2_k127_2319991_7 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000156 161.0
YHH2_k127_2319991_8 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000005789 127.0
YHH2_k127_2319991_9 membrane protein, required for colicin V production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.000000000000000002048 91.0
YHH2_k127_253907_0 Antirepressor K07741 - - 0.0000000000000000000000001792 114.0
YHH2_k127_253907_1 addiction module antidote protein HigA K21498 - - 0.000000000000000000001069 97.0
YHH2_k127_253907_2 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 - - 0.00000000000000000001551 92.0
YHH2_k127_253907_3 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000002567 87.0
YHH2_k127_254269_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.405e-295 915.0
YHH2_k127_254269_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 9.941e-253 784.0
YHH2_k127_254269_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 507.0
YHH2_k127_254269_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 482.0
YHH2_k127_254269_12 TonB-dependent Receptor Plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 501.0
YHH2_k127_254269_13 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 445.0
YHH2_k127_254269_14 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 437.0
YHH2_k127_254269_15 COG3209 Rhs family protein K11021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 396.0
YHH2_k127_254269_16 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 363.0
YHH2_k127_254269_17 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 348.0
YHH2_k127_254269_18 Serine phosphatase RsbU, regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 343.0
YHH2_k127_254269_19 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 304.0
YHH2_k127_254269_2 Type II IV secretion system protein K02652 - - 3.274e-249 775.0
YHH2_k127_254269_20 PFAM Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 297.0
YHH2_k127_254269_21 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000296 285.0
YHH2_k127_254269_22 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006924 274.0
YHH2_k127_254269_23 PFAM Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007714 262.0
YHH2_k127_254269_24 acid phosphatase activity K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000001031 223.0
YHH2_k127_254269_25 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000002161 197.0
YHH2_k127_254269_26 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000006298 200.0
YHH2_k127_254269_27 DoxX K15977 - - 0.000000000000000000000000000000000000000000000000001149 189.0
YHH2_k127_254269_28 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000009283 169.0
YHH2_k127_254269_29 Chitinase class I - - - 0.0000000000000000000000000000000000000000008163 165.0
YHH2_k127_254269_3 argininosuccinate lyase K01755 - 4.3.2.1 1.159e-225 706.0
YHH2_k127_254269_30 endopeptidase activity - - - 0.000000000000000000000000000000000000001209 173.0
YHH2_k127_254269_31 PFAM Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000000009164 147.0
YHH2_k127_254269_32 nucleotidyltransferase activity K07075 - - 0.000000000000000000000000000000006171 128.0
YHH2_k127_254269_33 - - - - 0.0000000000000000000000000000000226 130.0
YHH2_k127_254269_34 PIN domain K18828 - - 0.00000000000000000000000000000007783 128.0
YHH2_k127_254269_35 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000007895 130.0
YHH2_k127_254269_36 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.00000000000000000000000000001672 134.0
YHH2_k127_254269_37 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000002289 121.0
YHH2_k127_254269_38 cellulose binding - - - 0.0000000000000000001766 106.0
YHH2_k127_254269_4 TonB-dependent Receptor Plug K02014 - - 2.619e-221 708.0
YHH2_k127_254269_41 Protein of unknown function (DUF3301) - - - 0.000000009094 61.0
YHH2_k127_254269_42 cellulose binding K15924 - 3.2.1.136 0.00000003768 68.0
YHH2_k127_254269_43 cellulose binding - - - 0.0000004458 65.0
YHH2_k127_254269_44 - - - - 0.000001337 63.0
YHH2_k127_254269_45 Protein conserved in bacteria - - - 0.000001759 63.0
YHH2_k127_254269_46 - - - - 0.00004506 51.0
YHH2_k127_254269_47 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00006045 46.0
YHH2_k127_254269_48 Tetratricopeptide repeat - - - 0.0005937 52.0
YHH2_k127_254269_49 Bacteriophage CI repressor helix-turn-helix domain - - - 0.000928 50.0
YHH2_k127_254269_5 cell division protein K03466 - - 6.459e-207 665.0
YHH2_k127_254269_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 7.375e-206 646.0
YHH2_k127_254269_7 Receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 576.0
YHH2_k127_254269_8 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 552.0
YHH2_k127_254269_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 524.0
YHH2_k127_2674197_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.068e-212 668.0
YHH2_k127_2674197_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 567.0
YHH2_k127_2674197_10 COGs COG5381 conserved - - - 0.000000000000000000000000000000000000000000000008695 178.0
YHH2_k127_2674197_11 Domain of unknown function DUF29 - - - 0.00000000000000000000000000000000000000000000004054 175.0
YHH2_k127_2674197_12 - - - - 0.00000000000000000000000000000000000000005794 158.0
YHH2_k127_2674197_13 of the cupin superfamily K06995 - - 0.000000000000000000000000000000000002944 138.0
YHH2_k127_2674197_14 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively - - - 0.00000000000000000000000000000000005993 145.0
YHH2_k127_2674197_15 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000009957 124.0
YHH2_k127_2674197_16 COGs COG5439 conserved - - - 0.0000000000000000000000000006112 116.0
YHH2_k127_2674197_17 AntA/AntB antirepressor K07741 - - 0.00000000000000000000001937 109.0
YHH2_k127_2674197_18 Antirepressor K07741 - - 0.00000000000000000000002307 106.0
YHH2_k127_2674197_19 Putative restriction endonuclease - - - 0.00000000000000002405 87.0
YHH2_k127_2674197_2 Pfam Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 499.0
YHH2_k127_2674197_20 - - - - 0.00000000000000004007 83.0
YHH2_k127_2674197_21 - - - - 0.000000004794 64.0
YHH2_k127_2674197_22 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000005898 53.0
YHH2_k127_2674197_23 Domain of unknown function (DUF4160) - - - 0.00007671 46.0
YHH2_k127_2674197_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 469.0
YHH2_k127_2674197_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 426.0
YHH2_k127_2674197_5 Fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 416.0
YHH2_k127_2674197_6 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 378.0
YHH2_k127_2674197_7 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 362.0
YHH2_k127_2674197_9 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000000000000000000000000000000000005995 227.0
YHH2_k127_2778444_0 Histidine kinase - - - 0.0 1059.0
YHH2_k127_2778444_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB - - - 2.178e-287 894.0
YHH2_k127_2778444_10 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 331.0
YHH2_k127_2778444_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 332.0
YHH2_k127_2778444_12 Response regulator receiver K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009163 323.0
YHH2_k127_2778444_13 PFAM Ion transport K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 317.0
YHH2_k127_2778444_14 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 291.0
YHH2_k127_2778444_15 PFAM Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 311.0
YHH2_k127_2778444_16 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 288.0
YHH2_k127_2778444_18 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000003055 267.0
YHH2_k127_2778444_19 lytic transglycosylase activity K03194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001818 263.0
YHH2_k127_2778444_2 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 2.915e-251 781.0
YHH2_k127_2778444_20 TIGRFAM glycosyl transferase, WecB TagA CpsF family K05946,K13660 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 264.0
YHH2_k127_2778444_21 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000251 261.0
YHH2_k127_2778444_22 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000002441 207.0
YHH2_k127_2778444_23 HupE / UreJ protein K03192 - - 0.000000000000000000000000000000000000000000000000000001254 197.0
YHH2_k127_2778444_24 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000000004526 189.0
YHH2_k127_2778444_25 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000002917 194.0
YHH2_k127_2778444_26 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.000000000000000000000000000000000000000000000001975 179.0
YHH2_k127_2778444_27 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.00000000000000000000000000000000000000000000002277 172.0
YHH2_k127_2778444_28 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000001218 175.0
YHH2_k127_2778444_29 - - - - 0.00000000000000000000000000000000000002247 150.0
YHH2_k127_2778444_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 5.736e-210 665.0
YHH2_k127_2778444_30 Pfam Tetratricopeptide K07114 - - 0.0000000000000000000000000000000007387 140.0
YHH2_k127_2778444_31 - - - - 0.0000000000000000000006961 96.0
YHH2_k127_2778444_32 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000005206 99.0
YHH2_k127_2778444_33 - - - - 0.00001804 57.0
YHH2_k127_2778444_4 alanine symporter K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 586.0
YHH2_k127_2778444_5 Signal Transduction Histidine Kinase K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 517.0
YHH2_k127_2778444_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 416.0
YHH2_k127_2778444_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 373.0
YHH2_k127_2778444_8 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 344.0
YHH2_k127_2778444_9 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 335.0
YHH2_k127_2784254_0 - - - - 0.0 1436.0
YHH2_k127_2784254_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07711,K19694 - 2.7.13.3 0.0 1324.0
YHH2_k127_2784254_10 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 526.0
YHH2_k127_2784254_11 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 539.0
YHH2_k127_2784254_12 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 511.0
YHH2_k127_2784254_13 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 498.0
YHH2_k127_2784254_14 Bacterial regulatory protein, Fis family K10912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 486.0
YHH2_k127_2784254_15 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 457.0
YHH2_k127_2784254_16 DNA modification K07317 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 450.0
YHH2_k127_2784254_17 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 391.0
YHH2_k127_2784254_18 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 382.0
YHH2_k127_2784254_19 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
YHH2_k127_2784254_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1090.0
YHH2_k127_2784254_20 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 308.0
YHH2_k127_2784254_21 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 303.0
YHH2_k127_2784254_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001114 289.0
YHH2_k127_2784254_23 Short C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000657 262.0
YHH2_k127_2784254_24 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000102 248.0
YHH2_k127_2784254_26 High frequency lysogenization protein hflD homolog K07153 - - 0.00000000000000000000000000000000000000000000000000000004664 202.0
YHH2_k127_2784254_27 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000005012 181.0
YHH2_k127_2784254_28 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000003603 156.0
YHH2_k127_2784254_29 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.000000000000000000000000000000000002059 140.0
YHH2_k127_2784254_3 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1052.0
YHH2_k127_2784254_30 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000005753 154.0
YHH2_k127_2784254_31 PFAM OsmC family protein - - - 0.00000000000000000000000000000000002291 139.0
YHH2_k127_2784254_33 - - - - 0.0000000000000000000000000001139 122.0
YHH2_k127_2784254_34 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000189 111.0
YHH2_k127_2784254_35 - - - - 0.0000000000000000000000002701 121.0
YHH2_k127_2784254_36 FimV N-terminal domain protein - - - 0.0000000000000812 83.0
YHH2_k127_2784254_37 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000002528 64.0
YHH2_k127_2784254_38 Methionine biosynthesis protein MetW - - - 0.000000000101 66.0
YHH2_k127_2784254_4 Condensation domain - - - 1.409e-239 781.0
YHH2_k127_2784254_5 MGS-like domain - - - 3.458e-202 639.0
YHH2_k127_2784254_6 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 597.0
YHH2_k127_2784254_7 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 585.0
YHH2_k127_2784254_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 571.0
YHH2_k127_2784254_9 aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 528.0
YHH2_k127_2944949_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 2.269e-202 646.0
YHH2_k127_2944949_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000004062 196.0
YHH2_k127_2944949_2 - - - - 0.00000000000000000000000000005466 117.0
YHH2_k127_2944949_3 - - - - 0.00000000000000000000000000361 112.0
YHH2_k127_2944949_4 - - - - 0.0000000000000000000004974 95.0
YHH2_k127_2944949_5 - - - - 0.0000000000003316 71.0
YHH2_k127_2944949_8 - - - - 0.0000000003727 60.0
YHH2_k127_2960444_0 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000001606 84.0
YHH2_k127_2960444_1 Transglycosylase SLT domain - - - 0.00000000000006498 85.0
YHH2_k127_2960444_2 - - - - 0.0001678 53.0
YHH2_k127_3157444_0 Lactonase, 7-bladed beta-propeller - - - 0.0 1219.0
YHH2_k127_3157444_1 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1182.0
YHH2_k127_3157444_10 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 601.0
YHH2_k127_3157444_11 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 593.0
YHH2_k127_3157444_12 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 548.0
YHH2_k127_3157444_13 Belongs to the DegT DnrJ EryC1 family K02805,K13017,K18653 - 2.6.1.104,2.6.1.59,2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 542.0
YHH2_k127_3157444_14 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 532.0
YHH2_k127_3157444_15 Signal Transduction Histidine Kinase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 572.0
YHH2_k127_3157444_16 Oxidoreductase family, C-terminal alpha/beta domain K13020 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 524.0
YHH2_k127_3157444_17 response regulator receiver K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 534.0
YHH2_k127_3157444_18 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 496.0
YHH2_k127_3157444_19 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 498.0
YHH2_k127_3157444_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7e-323 1000.0
YHH2_k127_3157444_20 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 491.0
YHH2_k127_3157444_21 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 465.0
YHH2_k127_3157444_22 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009028 449.0
YHH2_k127_3157444_23 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 457.0
YHH2_k127_3157444_24 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 450.0
YHH2_k127_3157444_25 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 434.0
YHH2_k127_3157444_26 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 425.0
YHH2_k127_3157444_27 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 415.0
YHH2_k127_3157444_28 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 354.0
YHH2_k127_3157444_29 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 339.0
YHH2_k127_3157444_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.836e-316 975.0
YHH2_k127_3157444_30 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 321.0
YHH2_k127_3157444_31 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
YHH2_k127_3157444_32 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 298.0
YHH2_k127_3157444_33 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 294.0
YHH2_k127_3157444_34 COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 292.0
YHH2_k127_3157444_35 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000212 283.0
YHH2_k127_3157444_36 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001157 259.0
YHH2_k127_3157444_37 - K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000009232 233.0
YHH2_k127_3157444_38 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000003207 196.0
YHH2_k127_3157444_39 Pilin (bacterial filament) K02650 - - 0.000000000000000000000000000000000000000000004416 168.0
YHH2_k127_3157444_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 7.713e-282 873.0
YHH2_k127_3157444_40 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.000000000000000000000000000000000000004654 158.0
YHH2_k127_3157444_41 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000001009 146.0
YHH2_k127_3157444_42 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000001089 145.0
YHH2_k127_3157444_43 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000000005627 133.0
YHH2_k127_3157444_44 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000004183 130.0
YHH2_k127_3157444_45 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000005745 126.0
YHH2_k127_3157444_46 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000003505 114.0
YHH2_k127_3157444_47 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000000002393 100.0
YHH2_k127_3157444_48 Belongs to the N-Me-Phe pilin family K02650 - - 0.0000000000000000000008003 100.0
YHH2_k127_3157444_49 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.00000000000000002147 85.0
YHH2_k127_3157444_5 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 6.041e-271 866.0
YHH2_k127_3157444_50 mercury ion transmembrane transporter activity K07213 - - 0.0000000000001056 72.0
YHH2_k127_3157444_51 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000002825 65.0
YHH2_k127_3157444_52 Domain of unknown function (DUF4845) - - - 0.000000004008 63.0
YHH2_k127_3157444_6 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.918e-253 796.0
YHH2_k127_3157444_7 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.795e-252 781.0
YHH2_k127_3157444_8 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.991e-220 690.0
YHH2_k127_3157444_9 STAS domain - - - 1.751e-195 626.0
YHH2_k127_3391107_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 9.485e-273 855.0
YHH2_k127_3391107_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 1.473e-268 837.0
YHH2_k127_3391107_10 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 374.0
YHH2_k127_3391107_11 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004202 290.0
YHH2_k127_3391107_12 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004008 255.0
YHH2_k127_3391107_13 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000006067 248.0
YHH2_k127_3391107_14 PFAM Response regulator receiver domain K07689 - - 0.00000000000000000000000000000000000000000000000000000000000002038 220.0
YHH2_k127_3391107_15 PFAM Exonuclease RNase T and DNA polymerase III - - - 0.00000000000000000000000000000000000000000000000005928 182.0
YHH2_k127_3391107_16 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000000000000000000001227 179.0
YHH2_k127_3391107_17 Histidine kinase K07675 - 2.7.13.3 0.0000000000000000000000000000000000000000000000003008 197.0
YHH2_k127_3391107_18 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000005894 165.0
YHH2_k127_3391107_19 V-type proton ATPase subunit E K02121 - - 0.00000000000000000000000000000000001043 143.0
YHH2_k127_3391107_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 6.112e-214 674.0
YHH2_k127_3391107_20 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000000000000000000985 145.0
YHH2_k127_3391107_21 guanyl-nucleotide exchange factor activity K01387,K07114,K12287 - 3.4.24.3 0.000000000000000000000000000000298 143.0
YHH2_k127_3391107_22 Phage regulatory protein Rha (Phage_pRha) - - - 0.000000000000000000004889 98.0
YHH2_k127_3391107_23 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000000006799 94.0
YHH2_k127_3391107_24 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively - - - 0.0000000000000000009796 102.0
YHH2_k127_3391107_26 - - - - 0.000000000000000004824 86.0
YHH2_k127_3391107_27 domain, Protein - - - 0.00000000001831 78.0
YHH2_k127_3391107_29 - - - - 0.0000001056 61.0
YHH2_k127_3391107_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.706e-204 642.0
YHH2_k127_3391107_30 Conserved repeat domain - - - 0.000002566 61.0
YHH2_k127_3391107_31 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0001588 51.0
YHH2_k127_3391107_4 B-1 B cell differentiation - - - 3.233e-201 668.0
YHH2_k127_3391107_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.423e-200 632.0
YHH2_k127_3391107_6 Exonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 613.0
YHH2_k127_3391107_7 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009287 516.0
YHH2_k127_3391107_8 Surface antigen variable number K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 471.0
YHH2_k127_3391107_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 418.0
YHH2_k127_3474779_0 peptidyl-tyrosine sulfation - - - 0.0 1175.0
YHH2_k127_3474779_1 Histidine kinase - - - 1.035e-275 886.0
YHH2_k127_3474779_10 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 411.0
YHH2_k127_3474779_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 368.0
YHH2_k127_3474779_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005553 273.0
YHH2_k127_3474779_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000009335 237.0
YHH2_k127_3474779_14 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000008661 149.0
YHH2_k127_3474779_15 PFAM PilT protein domain protein - - - 0.0000000000000000000000000000000000002929 144.0
YHH2_k127_3474779_16 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000007355 124.0
YHH2_k127_3474779_17 - - - - 0.000000000000000000000001163 108.0
YHH2_k127_3474779_18 Cytochrome c - - - 0.0000000000000003489 82.0
YHH2_k127_3474779_19 Unextendable partial coding region - - - 0.000000000000001115 77.0
YHH2_k127_3474779_2 Histidine kinase - - - 1.14e-258 818.0
YHH2_k127_3474779_20 serine-type aminopeptidase activity - - - 0.00000000003763 69.0
YHH2_k127_3474779_21 - - - - 0.0000000007151 59.0
YHH2_k127_3474779_23 response regulator receiver - - - 0.00000000241 59.0
YHH2_k127_3474779_24 P63C domain - - - 0.000502 52.0
YHH2_k127_3474779_3 Diguanylate cyclase - - - 7.477e-239 776.0
YHH2_k127_3474779_4 PFAM Aminotransferase class I and II K14261 - - 1.06e-221 691.0
YHH2_k127_3474779_5 response regulator receiver - - - 6.431e-216 677.0
YHH2_k127_3474779_6 Serine Threonine protein kinase - - - 1.884e-205 706.0
YHH2_k127_3474779_7 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 610.0
YHH2_k127_3474779_8 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 517.0
YHH2_k127_3474779_9 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 426.0
YHH2_k127_3476820_0 PFAM Archaeal ATPase - - - 3.852e-308 972.0
YHH2_k127_3476820_1 CHAT domain - - - 3.499e-246 783.0
YHH2_k127_3476820_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 355.0
YHH2_k127_3476820_11 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 337.0
YHH2_k127_3476820_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 317.0
YHH2_k127_3476820_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 313.0
YHH2_k127_3476820_14 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005495 244.0
YHH2_k127_3476820_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000003651 231.0
YHH2_k127_3476820_16 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000004361 230.0
YHH2_k127_3476820_17 UPF0114 protein - - - 0.00000000000000000000000000000000000000000000000000000001741 203.0
YHH2_k127_3476820_18 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000000155 160.0
YHH2_k127_3476820_19 Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000004656 160.0
YHH2_k127_3476820_2 TrkA-N domain K03499 - - 2.716e-244 759.0
YHH2_k127_3476820_20 Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000006835 165.0
YHH2_k127_3476820_21 TerD domain - - - 0.0000000000000000000000000000000000000001593 156.0
YHH2_k127_3476820_22 Transposase - - - 0.0000000000000000000000000000000000000005545 161.0
YHH2_k127_3476820_23 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000000000000000000000000000000006955 152.0
YHH2_k127_3476820_24 negative regulation of DNA recombination K01481,K07456,K15577 - 3.5.3.15 0.000000000000000000000000000007995 129.0
YHH2_k127_3476820_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000004941 98.0
YHH2_k127_3476820_27 Prokaryotic N-terminal methylation motif K02459 - - 0.00000000000000007786 89.0
YHH2_k127_3476820_28 - - - - 0.0000000000000001958 94.0
YHH2_k127_3476820_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.0000000000000005364 80.0
YHH2_k127_3476820_3 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 3.892e-216 685.0
YHH2_k127_3476820_30 - K02456 - - 0.0000000000002731 76.0
YHH2_k127_3476820_31 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000004571 73.0
YHH2_k127_3476820_32 HTH transcriptional regulator, MerR - - - 0.0000000008363 60.0
YHH2_k127_3476820_33 TIGRFAM death-on-curing family protein K07341 - - 0.000001046 53.0
YHH2_k127_3476820_4 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 542.0
YHH2_k127_3476820_5 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 538.0
YHH2_k127_3476820_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 511.0
YHH2_k127_3476820_7 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 454.0
YHH2_k127_3476820_8 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 425.0
YHH2_k127_3476820_9 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 416.0
YHH2_k127_3490749_0 ATPase involved in DNA repair - - - 0.0 2203.0
YHH2_k127_3490749_1 Subtilase family - - - 3.873e-278 880.0
YHH2_k127_3490749_10 TIGRFAM general secretion pathway protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 492.0
YHH2_k127_3490749_11 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 488.0
YHH2_k127_3490749_12 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 483.0
YHH2_k127_3490749_13 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 467.0
YHH2_k127_3490749_14 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 449.0
YHH2_k127_3490749_15 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 439.0
YHH2_k127_3490749_16 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 451.0
YHH2_k127_3490749_17 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 428.0
YHH2_k127_3490749_18 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 416.0
YHH2_k127_3490749_19 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 403.0
YHH2_k127_3490749_2 Histidine kinase-like ATPases - - - 1.795e-213 679.0
YHH2_k127_3490749_20 archaeal coiled-coil protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 391.0
YHH2_k127_3490749_21 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 386.0
YHH2_k127_3490749_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 394.0
YHH2_k127_3490749_23 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 374.0
YHH2_k127_3490749_24 TIGRFAM KamA family protein K19810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 356.0
YHH2_k127_3490749_25 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 348.0
YHH2_k127_3490749_26 CBS-domain-containing membrane protein K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 350.0
YHH2_k127_3490749_27 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 346.0
YHH2_k127_3490749_28 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 342.0
YHH2_k127_3490749_29 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 345.0
YHH2_k127_3490749_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.793e-204 643.0
YHH2_k127_3490749_30 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 341.0
YHH2_k127_3490749_31 Adenine specific DNA methylase Mod - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 353.0
YHH2_k127_3490749_32 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007537 315.0
YHH2_k127_3490749_33 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 325.0
YHH2_k127_3490749_34 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 294.0
YHH2_k127_3490749_35 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 284.0
YHH2_k127_3490749_36 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 265.0
YHH2_k127_3490749_37 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 263.0
YHH2_k127_3490749_38 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000004113 259.0
YHH2_k127_3490749_39 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001692 252.0
YHH2_k127_3490749_4 PFAM aminotransferase class-III K01845 - 5.4.3.8 8.455e-202 635.0
YHH2_k127_3490749_40 Conserved hypothetical ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005547 249.0
YHH2_k127_3490749_41 CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002818 260.0
YHH2_k127_3490749_42 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000005664 209.0
YHH2_k127_3490749_43 PFAM AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000191 225.0
YHH2_k127_3490749_45 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000000000002803 184.0
YHH2_k127_3490749_46 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000007625 197.0
YHH2_k127_3490749_47 - - - - 0.0000000000000000000000000000000000000000000000146 177.0
YHH2_k127_3490749_48 photosystem II stabilization - - - 0.000000000000000000000000000000000000000000002327 170.0
YHH2_k127_3490749_49 PFAM Gram-negative bacterial tonB protein K03832 - - 0.00000000000000000000000000000000000000000008873 171.0
YHH2_k127_3490749_5 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 611.0
YHH2_k127_3490749_50 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000000000000003996 155.0
YHH2_k127_3490749_51 - - - - 0.00000000000000000000000000000000000000362 162.0
YHH2_k127_3490749_52 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000002503 161.0
YHH2_k127_3490749_53 Addiction module toxin K19158 - - 0.0000000000000000000000000000000000009852 139.0
YHH2_k127_3490749_54 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000008379 137.0
YHH2_k127_3490749_55 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000001359 140.0
YHH2_k127_3490749_56 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000002921 138.0
YHH2_k127_3490749_57 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000001763 133.0
YHH2_k127_3490749_58 TIGRFAM Addiction module toxin, Txe YoeB K19158 - - 0.0000000000000000000000000000000002018 134.0
YHH2_k127_3490749_59 - - - - 0.000000000000000000000000000000003075 132.0
YHH2_k127_3490749_6 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 566.0
YHH2_k127_3490749_60 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000001153 131.0
YHH2_k127_3490749_61 - - - - 0.00000000000000000000000000185 119.0
YHH2_k127_3490749_62 Protein of unknown function (DUF2442) - - - 0.000000000000000000000003211 106.0
YHH2_k127_3490749_64 - - - - 0.000000000000000000000009748 109.0
YHH2_k127_3490749_65 - - - - 0.0000000000000000000003655 104.0
YHH2_k127_3490749_66 5'-nucleotidase, C-terminal domain - - - 0.0000000000000000002392 100.0
YHH2_k127_3490749_67 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000005787 86.0
YHH2_k127_3490749_69 TIGRFAM Transposase, IS605 OrfB, C-terminal - - - 0.0000000000000002306 82.0
YHH2_k127_3490749_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 565.0
YHH2_k127_3490749_70 protein involved in outer membrane biogenesis K07289 - - 0.000000000000006994 89.0
YHH2_k127_3490749_71 RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities - - - 0.0000000000005811 79.0
YHH2_k127_3490749_72 - - - - 0.0000000001101 64.0
YHH2_k127_3490749_73 RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities K03607 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003727,GO:0003729,GO:0003730,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006974,GO:0007154,GO:0007165,GO:0007231,GO:0008150,GO:0009628,GO:0009651,GO:0009987,GO:0010468,GO:0010608,GO:0010958,GO:0019222,GO:0023052,GO:0032879,GO:0032890,GO:0032892,GO:0033554,GO:0033592,GO:0034057,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0042538,GO:0042710,GO:0043269,GO:0043270,GO:0044010,GO:0044070,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0048518,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051704,GO:0051716,GO:0051952,GO:0051954,GO:0051955,GO:0051957,GO:0060255,GO:0065007,GO:0070881,GO:0071214,GO:0071470,GO:0071472,GO:0071474,GO:0071475,GO:0097159,GO:0097617,GO:0104004,GO:1901363,GO:1902834,GO:1902836,GO:1903789,GO:1903793,GO:1903959,GO:1903961,GO:1904062,GO:1904064 - 0.0000000006352 70.0
YHH2_k127_3490749_74 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.0000001996 53.0
YHH2_k127_3490749_75 - - - - 0.0000009226 53.0
YHH2_k127_3490749_76 KilA-N - - - 0.000008926 51.0
YHH2_k127_3490749_77 Sphaeroforma arctica JP610 - - - 0.0001643 45.0
YHH2_k127_3490749_79 Acts as a magnesium transporter K06213 - - 0.0009163 43.0
YHH2_k127_3490749_8 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 533.0
YHH2_k127_3490749_80 Protein of unknown function (DUF2281) - - - 0.0009201 45.0
YHH2_k127_3490749_9 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 508.0
YHH2_k127_3493231_0 ATP-dependent helicase K03578 - 3.6.4.13 0.0 1638.0
YHH2_k127_3493231_1 type II restriction enzyme, methylase - - - 0.0 1253.0
YHH2_k127_3493231_10 transporter, dctM subunit - - - 5.677e-195 616.0
YHH2_k127_3493231_100 Phosphopantetheine attachment site - - - 0.0000000000005034 71.0
YHH2_k127_3493231_101 - - - - 0.000000000003373 72.0
YHH2_k127_3493231_102 PIN domain - - - 0.00000000002734 65.0
YHH2_k127_3493231_103 - - - - 0.000000008755 60.0
YHH2_k127_3493231_105 Large extracellular alpha-helical protein - - - 0.000000105 67.0
YHH2_k127_3493231_106 Tfp pilus assembly protein FimV K08086 - - 0.0000002405 63.0
YHH2_k127_3493231_107 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000003146 66.0
YHH2_k127_3493231_109 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0001663 53.0
YHH2_k127_3493231_11 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 611.0
YHH2_k127_3493231_111 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0004591 45.0
YHH2_k127_3493231_12 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 623.0
YHH2_k127_3493231_13 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 604.0
YHH2_k127_3493231_14 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 597.0
YHH2_k127_3493231_15 PFAM aminotransferase class-III K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 556.0
YHH2_k127_3493231_16 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 543.0
YHH2_k127_3493231_17 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 523.0
YHH2_k127_3493231_18 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 523.0
YHH2_k127_3493231_19 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 527.0
YHH2_k127_3493231_2 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 5.079e-304 937.0
YHH2_k127_3493231_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 505.0
YHH2_k127_3493231_21 ABC transporter, ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 514.0
YHH2_k127_3493231_22 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 480.0
YHH2_k127_3493231_23 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 472.0
YHH2_k127_3493231_24 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 459.0
YHH2_k127_3493231_25 Mycolic acid cyclopropane synthetase K13042,K18897 GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052729,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.1.157,2.1.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 452.0
YHH2_k127_3493231_26 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 446.0
YHH2_k127_3493231_27 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 484.0
YHH2_k127_3493231_28 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 423.0
YHH2_k127_3493231_29 oxidoreductase, FAD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 426.0
YHH2_k127_3493231_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.596e-297 927.0
YHH2_k127_3493231_30 TIGRFAM 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 411.0
YHH2_k127_3493231_31 TIGRFAM Outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 440.0
YHH2_k127_3493231_32 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 385.0
YHH2_k127_3493231_33 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 403.0
YHH2_k127_3493231_34 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 389.0
YHH2_k127_3493231_35 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 380.0
YHH2_k127_3493231_36 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 378.0
YHH2_k127_3493231_37 PFAM Fructosamine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 375.0
YHH2_k127_3493231_38 Pfam:Gp37_Gp68 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 364.0
YHH2_k127_3493231_39 Mycolic acid cyclopropane synthetase K13042,K18897 GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052729,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.1.157,2.1.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 361.0
YHH2_k127_3493231_4 alpha-glucan phosphorylase K00688 - 2.4.1.1 9.896e-296 930.0
YHH2_k127_3493231_40 glycine betaine K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 357.0
YHH2_k127_3493231_41 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 367.0
YHH2_k127_3493231_42 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 340.0
YHH2_k127_3493231_43 PFAM YicC-like family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 325.0
YHH2_k127_3493231_44 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 322.0
YHH2_k127_3493231_45 Histidine kinase K17292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 326.0
YHH2_k127_3493231_46 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 310.0
YHH2_k127_3493231_47 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 341.0
YHH2_k127_3493231_48 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 311.0
YHH2_k127_3493231_49 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006931 296.0
YHH2_k127_3493231_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.655e-295 915.0
YHH2_k127_3493231_50 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 289.0
YHH2_k127_3493231_51 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 299.0
YHH2_k127_3493231_52 Predicted integral membrane protein (DUF2269) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004897 279.0
YHH2_k127_3493231_53 PFAM Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008314 286.0
YHH2_k127_3493231_54 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 298.0
YHH2_k127_3493231_55 polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001312 273.0
YHH2_k127_3493231_56 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003289 271.0
YHH2_k127_3493231_57 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001727 266.0
YHH2_k127_3493231_58 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001041 258.0
YHH2_k127_3493231_59 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000108 259.0
YHH2_k127_3493231_6 Arginyl-tRNA synthetase K01887 - 6.1.1.19 5.301e-244 766.0
YHH2_k127_3493231_60 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000002583 236.0
YHH2_k127_3493231_61 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000009536 253.0
YHH2_k127_3493231_62 Glycosyl transferases group 1 K16150 - 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000003894 224.0
YHH2_k127_3493231_63 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000004052 219.0
YHH2_k127_3493231_64 Putative beta-barrel porin 2 K20920 - - 0.00000000000000000000000000000000000000000000000000000000000004408 229.0
YHH2_k127_3493231_65 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000002982 218.0
YHH2_k127_3493231_66 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000001214 211.0
YHH2_k127_3493231_67 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000009945 192.0
YHH2_k127_3493231_68 Glycosyl transferases group 1 K16150 - 2.4.1.11 0.00000000000000000000000000000000000000000000000000001312 194.0
YHH2_k127_3493231_69 Membrane protein involved in D-alanine export K03739,K19294 - - 0.000000000000000000000000000000000000000000000000000466 199.0
YHH2_k127_3493231_7 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 7.129e-222 693.0
YHH2_k127_3493231_70 - - - - 0.0000000000000000000000000000000000000000000001644 174.0
YHH2_k127_3493231_71 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000019 196.0
YHH2_k127_3493231_72 Belongs to the Orn Lys Arg decarboxylase class-II family K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000003353 171.0
YHH2_k127_3493231_73 PFAM MotA TolQ ExbB proton channel family K03561 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000004544 171.0
YHH2_k127_3493231_74 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000007963 167.0
YHH2_k127_3493231_75 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000001518 154.0
YHH2_k127_3493231_76 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000002758 157.0
YHH2_k127_3493231_77 Lytic transglycosylase catalytic K08307 - - 0.00000000000000000000000000000000000004615 158.0
YHH2_k127_3493231_78 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000000000000001262 147.0
YHH2_k127_3493231_79 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000001781 149.0
YHH2_k127_3493231_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.236e-210 673.0
YHH2_k127_3493231_80 phosphonoacetaldehyde hydrolase activity K01489 - 3.5.4.5 0.00000000000000000000000000000000001041 156.0
YHH2_k127_3493231_82 TIGRFAM death-on-curing family protein K07341 - - 0.00000000000000000000000000000000763 130.0
YHH2_k127_3493231_83 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.0000000000000000000000000000002958 126.0
YHH2_k127_3493231_84 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000000000000001135 122.0
YHH2_k127_3493231_85 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000005755 128.0
YHH2_k127_3493231_86 Helix-turn-helix K07726 - - 0.0000000000000000000000000001047 117.0
YHH2_k127_3493231_87 COG0839 NADH ubiquinone oxidoreductase subunit 6 (chain J) K00339 - 1.6.5.3 0.0000000000000000000000000003253 120.0
YHH2_k127_3493231_88 BRO family, N-terminal domain - - - 0.000000000000000000000000001542 123.0
YHH2_k127_3493231_89 Sporulation related domain - - - 0.0000000000000000000000003552 113.0
YHH2_k127_3493231_9 COG2274 ABC-type bacteriocin lantibiotic exporters, contain an N-terminal double-glycine peptidase domain K13409 - - 3.039e-203 662.0
YHH2_k127_3493231_90 PFAM acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000127 102.0
YHH2_k127_3493231_91 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.00000000000000000000001553 104.0
YHH2_k127_3493231_92 P22_AR N-terminal domain - - - 0.000000000000000000007952 100.0
YHH2_k127_3493231_93 PIN domain - - - 0.000000000000000000008799 93.0
YHH2_k127_3493231_94 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000005747 99.0
YHH2_k127_3493231_95 - - - - 0.0000000000000000001313 99.0
YHH2_k127_3493231_96 PAN domain - - - 0.000000000000000004755 98.0
YHH2_k127_3493231_97 LysM domain K01448,K08307,K19223,K22278 - 3.5.1.104,3.5.1.28 0.000000000000000007384 90.0
YHH2_k127_3493231_98 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.0000000000000008292 81.0
YHH2_k127_3493231_99 repressor - - - 0.00000000000007685 77.0
YHH2_k127_3685341_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1180.0
YHH2_k127_3685341_1 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1161.0
YHH2_k127_3685341_10 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 403.0
YHH2_k127_3685341_11 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 388.0
YHH2_k127_3685341_12 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 333.0
YHH2_k127_3685341_13 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 304.0
YHH2_k127_3685341_14 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
YHH2_k127_3685341_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 305.0
YHH2_k127_3685341_16 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 293.0
YHH2_k127_3685341_17 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 283.0
YHH2_k127_3685341_18 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000003889 204.0
YHH2_k127_3685341_19 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000007801 217.0
YHH2_k127_3685341_2 Histidine kinase - - - 0.0 1093.0
YHH2_k127_3685341_20 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000003613 210.0
YHH2_k127_3685341_21 Type II secretion system (T2SS), protein K - - - 0.0000000000000000000000000000000000000003518 163.0
YHH2_k127_3685341_22 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000001224 146.0
YHH2_k127_3685341_23 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000002865 121.0
YHH2_k127_3685341_25 transferase activity, transferring acyl groups other than amino-acyl groups K01897,K03466,K18687 - 6.2.1.3,6.2.1.41 0.0000000004356 64.0
YHH2_k127_3685341_26 PFAM peptidase M4 thermolysin - - - 0.0000568 55.0
YHH2_k127_3685341_3 serine threonine protein kinase K12132 - 2.7.11.1 9.217e-260 827.0
YHH2_k127_3685341_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526,K03676 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 543.0
YHH2_k127_3685341_5 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 544.0
YHH2_k127_3685341_6 transferase activity, transferring acyl groups other than amino-acyl groups K01897,K03466,K18687 - 6.2.1.3,6.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 548.0
YHH2_k127_3685341_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 526.0
YHH2_k127_3685341_8 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 439.0
YHH2_k127_3685341_9 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 402.0
YHH2_k127_3835371_0 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1158.0
YHH2_k127_3835371_1 Molecular chaperone. Has ATPase activity K04079 - - 1.54e-308 956.0
YHH2_k127_3835371_10 dihydroneopterin triphosphate K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.6.1.67 0.00000000000000000000000000000000000000000000007124 172.0
YHH2_k127_3835371_11 protein conserved in bacteria K11022 - - 0.00000000000000000000000000000000000004072 146.0
YHH2_k127_3835371_12 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000003878 131.0
YHH2_k127_3835371_13 Domain of unknown function (DUF4381) - - - 0.0000000000000000000000000009526 118.0
YHH2_k127_3835371_14 Protein of unknown function DUF58 - - - 0.000000000000000000000000007012 113.0
YHH2_k127_3835371_15 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000001335 64.0
YHH2_k127_3835371_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.188e-267 833.0
YHH2_k127_3835371_3 Histidine kinase K20973 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000639 402.0
YHH2_k127_3835371_4 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 386.0
YHH2_k127_3835371_5 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 370.0
YHH2_k127_3835371_6 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
YHH2_k127_3835371_7 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009453 276.0
YHH2_k127_3835371_8 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000002048 236.0
YHH2_k127_3835371_9 pfam ammecr1 - - - 0.0000000000000000000000000000000000000000000000000000000000000007055 224.0
YHH2_k127_3980381_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 7.59e-232 739.0
YHH2_k127_3980381_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000006541 229.0
YHH2_k127_3980381_2 endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000005972 182.0
YHH2_k127_3980381_3 Transposase, IS605 OrfB family K07496 - - 0.0000000000000000000000000000000000000000000000002118 180.0
YHH2_k127_3980381_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000002689 98.0
YHH2_k127_3980381_5 - - - - 0.00000000000005621 78.0
YHH2_k127_4064868_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 533.0
YHH2_k127_4064868_1 PELOTA RNA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 300.0
YHH2_k127_4064868_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000005587 222.0
YHH2_k127_4064868_3 Belongs to the ompA family - - - 0.000000000000000000000000000008209 124.0
YHH2_k127_4072840_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1337.0
YHH2_k127_4072840_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1139.0
YHH2_k127_4072840_10 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 449.0
YHH2_k127_4072840_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 442.0
YHH2_k127_4072840_12 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 435.0
YHH2_k127_4072840_13 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 377.0
YHH2_k127_4072840_14 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 374.0
YHH2_k127_4072840_15 Restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 378.0
YHH2_k127_4072840_16 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 338.0
YHH2_k127_4072840_17 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 338.0
YHH2_k127_4072840_18 PFAM GTP-binding protein HSR1-related K06946 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 347.0
YHH2_k127_4072840_19 TIGRFAM phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 328.0
YHH2_k127_4072840_2 4Fe-4S dicluster domain - - - 0.0 1060.0
YHH2_k127_4072840_20 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 311.0
YHH2_k127_4072840_21 cofactor biosynthesis protein NifB K02585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 306.0
YHH2_k127_4072840_22 protein-glutamate methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000001445 255.0
YHH2_k127_4072840_23 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000005783 225.0
YHH2_k127_4072840_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000007959 230.0
YHH2_k127_4072840_25 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000001593 211.0
YHH2_k127_4072840_26 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000004608 197.0
YHH2_k127_4072840_27 Ferredoxin - - - 0.00000000000000000000000000000000000000000000513 166.0
YHH2_k127_4072840_28 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000002455 156.0
YHH2_k127_4072840_29 - - - - 0.0000000000000000000000000000000000000004077 152.0
YHH2_k127_4072840_3 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 2.256e-276 857.0
YHH2_k127_4072840_30 - - - - 0.00000000000000000000000000000004576 129.0
YHH2_k127_4072840_31 P22_AR N-terminal domain - - - 0.000000000000000000000000000001071 129.0
YHH2_k127_4072840_32 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.0000000000000000000000048 103.0
YHH2_k127_4072840_33 - - - - 0.00000000000000001542 89.0
YHH2_k127_4072840_34 Helix-turn-helix domain - - - 0.00000000000000004045 84.0
YHH2_k127_4072840_35 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000006461 70.0
YHH2_k127_4072840_36 ParD-like antitoxin of type II bacterial toxin-antitoxin system - - - 0.000000000005319 68.0
YHH2_k127_4072840_37 KilA-N - - - 0.00000000003137 71.0
YHH2_k127_4072840_38 Right handed beta helix region - - - 0.00000000008176 76.0
YHH2_k127_4072840_4 M subunit K03427 - 2.1.1.72 9.497e-271 840.0
YHH2_k127_4072840_40 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.000000000179 61.0
YHH2_k127_4072840_42 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00001551 48.0
YHH2_k127_4072840_43 addiction module antidote protein, HigA family K21498 - - 0.0004857 43.0
YHH2_k127_4072840_5 Circularly permuted ATP-grasp type 2 - - - 1.581e-268 831.0
YHH2_k127_4072840_6 HD domain - - - 1.006e-236 743.0
YHH2_k127_4072840_7 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 562.0
YHH2_k127_4072840_8 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 514.0
YHH2_k127_4072840_9 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 494.0
YHH2_k127_4076482_0 Cytochrome c-type biogenesis protein CcmF C-terminal - - - 1.426e-297 924.0
YHH2_k127_4076482_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.113e-248 791.0
YHH2_k127_4076482_10 Conserved repeat domain - - - 0.0001773 56.0
YHH2_k127_4076482_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 2.838e-200 646.0
YHH2_k127_4076482_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 437.0
YHH2_k127_4076482_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000006419 211.0
YHH2_k127_4076482_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - 0.000000000000000000000000000000000000000000000000001422 186.0
YHH2_k127_4076482_6 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000007012 121.0
YHH2_k127_4076482_7 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000001729 116.0
YHH2_k127_4076482_8 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.000000000000000000006186 110.0
YHH2_k127_4076482_9 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.000000000006779 67.0
YHH2_k127_4158044_0 von Willebrand factor (vWF) type A domain K02448 - - 1.357e-241 766.0
YHH2_k127_4158044_1 LeuA allosteric (dimerisation) domain K09011 - 2.3.1.182 2.317e-234 734.0
YHH2_k127_4158044_10 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 297.0
YHH2_k127_4158044_11 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000008859 256.0
YHH2_k127_4158044_12 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000009809 222.0
YHH2_k127_4158044_13 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.000000000000000000000000000000000000000000000000000000007918 208.0
YHH2_k127_4158044_14 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000001324 201.0
YHH2_k127_4158044_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000002051 201.0
YHH2_k127_4158044_16 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000001454 190.0
YHH2_k127_4158044_17 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000001704 188.0
YHH2_k127_4158044_18 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000000004759 181.0
YHH2_k127_4158044_19 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000005356 171.0
YHH2_k127_4158044_2 Bacterial regulatory protein, Fis family K10912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 570.0
YHH2_k127_4158044_20 PFAM Peptidase family M23 - - - 0.00000000000000000000000000000000000000005791 158.0
YHH2_k127_4158044_21 - - - - 0.000000000000000000000000000006673 124.0
YHH2_k127_4158044_22 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000007311 119.0
YHH2_k127_4158044_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 505.0
YHH2_k127_4158044_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 486.0
YHH2_k127_4158044_5 1,4-alpha-glucan branching enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 437.0
YHH2_k127_4158044_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 411.0
YHH2_k127_4158044_7 Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 387.0
YHH2_k127_4158044_8 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 381.0
YHH2_k127_4158044_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 349.0
YHH2_k127_4173771_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.0 1522.0
YHH2_k127_4173771_1 Methyl-accepting chemotaxis protein (MCP) signaling domain - - - 0.0 1103.0
YHH2_k127_4173771_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 351.0
YHH2_k127_4173771_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 312.0
YHH2_k127_4173771_12 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 309.0
YHH2_k127_4173771_13 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 278.0
YHH2_k127_4173771_14 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002244 271.0
YHH2_k127_4173771_15 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 280.0
YHH2_k127_4173771_16 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001761 250.0
YHH2_k127_4173771_17 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000003778 240.0
YHH2_k127_4173771_18 TIGRFAM CRISPR-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000007799 223.0
YHH2_k127_4173771_19 Response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000000000000002123 216.0
YHH2_k127_4173771_2 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 5.768e-221 702.0
YHH2_k127_4173771_20 CheW-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000003624 215.0
YHH2_k127_4173771_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000004266 204.0
YHH2_k127_4173771_22 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000002033 192.0
YHH2_k127_4173771_23 - - - - 0.000000000000000000000000000000000000000000004301 167.0
YHH2_k127_4173771_25 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000001357 117.0
YHH2_k127_4173771_26 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01286,K07258 - 3.4.16.4 0.00000000000000000000000000713 119.0
YHH2_k127_4173771_27 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000007719 95.0
YHH2_k127_4173771_28 - - - - 0.00000000000000000001603 94.0
YHH2_k127_4173771_29 - - - - 0.0000000000000677 83.0
YHH2_k127_4173771_3 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 3.583e-208 662.0
YHH2_k127_4173771_31 Protein of unknown function (DUF433) - - - 0.00005418 46.0
YHH2_k127_4173771_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 585.0
YHH2_k127_4173771_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 582.0
YHH2_k127_4173771_6 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 550.0
YHH2_k127_4173771_7 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 388.0
YHH2_k127_4173771_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 375.0
YHH2_k127_4173771_9 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 360.0
YHH2_k127_4256280_0 Circularly permuted ATP-grasp type 2 - - - 0.0 1074.0
YHH2_k127_4256280_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 512.0
YHH2_k127_4256280_10 PFAM Archaeal ATPase - - - 0.0000000000000000000000000000000000001282 158.0
YHH2_k127_4256280_11 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000001296 163.0
YHH2_k127_4256280_12 domain, Protein K01874,K02230,K02487,K05366,K06596,K11751,K16147,K20470 - 2.4.1.129,2.4.99.16,3.1.3.5,3.4.16.4,3.6.1.45,6.1.1.10,6.6.1.2 0.0000000000000000000000000003728 129.0
YHH2_k127_4256280_13 - - - - 0.000001872 49.0
YHH2_k127_4256280_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 466.0
YHH2_k127_4256280_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 413.0
YHH2_k127_4256280_4 Response regulator receiver K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
YHH2_k127_4256280_5 Serine Threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 400.0
YHH2_k127_4256280_6 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 388.0
YHH2_k127_4256280_7 anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000007052 184.0
YHH2_k127_4256280_8 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000000000000000006205 177.0
YHH2_k127_4256280_9 Papain-like cysteine protease AvrRpt2 K06992 - - 0.0000000000000000000000000000000000000000001661 167.0
YHH2_k127_4423466_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 2.332e-261 813.0
YHH2_k127_4423466_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 3.581e-222 744.0
YHH2_k127_4423466_10 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 343.0
YHH2_k127_4423466_11 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 344.0
YHH2_k127_4423466_13 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001022 242.0
YHH2_k127_4423466_14 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006671 233.0
YHH2_k127_4423466_15 Glycosyltransferase like family 2 K16870 - 2.4.1.289 0.0000000000000000000000000000000000000000000000000000000000000001604 235.0
YHH2_k127_4423466_16 - - - - 0.00000000000000000000000000000000000000000000000002905 181.0
YHH2_k127_4423466_17 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000000000000006304 179.0
YHH2_k127_4423466_18 - - - - 0.00000000000000000000000000000000000000000000000148 184.0
YHH2_k127_4423466_19 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000001248 160.0
YHH2_k127_4423466_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 7.631e-197 621.0
YHH2_k127_4423466_20 - - - - 0.000000000000000000000000001395 112.0
YHH2_k127_4423466_21 exosortase interaction domain protein - - - 0.00000000000000000000004275 114.0
YHH2_k127_4423466_22 Extracellular nuclease K07004 - - 0.00000000000000000000009854 114.0
YHH2_k127_4423466_23 Helix-turn-helix domain - - - 0.000000000000000000001686 99.0
YHH2_k127_4423466_24 PFAM ORF6N domain - - - 0.000000000000000000002768 101.0
YHH2_k127_4423466_25 pilus organization K07346,K20276 - - 0.00000000000001038 88.0
YHH2_k127_4423466_27 Transposase, IS605 OrfB family K07496 - - 0.00000000000002752 74.0
YHH2_k127_4423466_28 - - - - 0.0000000000181 67.0
YHH2_k127_4423466_29 Putative transposase of IS4/5 family (DUF4096) - - - 0.000000004561 58.0
YHH2_k127_4423466_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 568.0
YHH2_k127_4423466_30 nuclease - - - 0.000000049 57.0
YHH2_k127_4423466_31 Arc-like DNA binding domain - - - 0.00004522 49.0
YHH2_k127_4423466_4 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 548.0
YHH2_k127_4423466_5 NAD(P)H-binding K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 535.0
YHH2_k127_4423466_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 478.0
YHH2_k127_4423466_7 HAD-hyrolase-like K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 437.0
YHH2_k127_4423466_8 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 380.0
YHH2_k127_4423466_9 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 342.0
YHH2_k127_4439251_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 6.161e-222 692.0
YHH2_k127_4439251_1 TonB-dependent Receptor Plug K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 531.0
YHH2_k127_4439251_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000008708 116.0
YHH2_k127_4439251_11 proteolysis - - - 0.0000000000000000000000002373 112.0
YHH2_k127_4439251_12 - - - - 0.00000000000000000000001011 109.0
YHH2_k127_4439251_13 endopeptidase activity - - - 0.00000000000000000002018 107.0
YHH2_k127_4439251_14 - - - - 0.00000000000000000004427 91.0
YHH2_k127_4439251_15 PIN domain - - - 0.00000000000000004049 83.0
YHH2_k127_4439251_16 Phage regulatory protein Rha (Phage_pRha) - - - 0.0000000001393 64.0
YHH2_k127_4439251_17 PIN domain - - - 0.0000000001835 64.0
YHH2_k127_4439251_18 Protein of unknown function (DUF2909) - - - 0.0000000006684 64.0
YHH2_k127_4439251_19 KilA-N - - - 0.000189 51.0
YHH2_k127_4439251_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 472.0
YHH2_k127_4439251_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 333.0
YHH2_k127_4439251_4 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 314.0
YHH2_k127_4439251_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009596 276.0
YHH2_k127_4439251_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000002775 231.0
YHH2_k127_4439251_7 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000006306 224.0
YHH2_k127_4439251_8 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000006306 211.0
YHH2_k127_4439251_9 regulation of response to stimulus - - - 0.00000000000000000000000000000003685 145.0
YHH2_k127_4525345_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 4.148e-243 773.0
YHH2_k127_4525345_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.122e-240 750.0
YHH2_k127_4525345_10 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000002008 168.0
YHH2_k127_4525345_11 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000000000004227 168.0
YHH2_k127_4525345_12 - - - - 0.00000000000000000000000000000000000000897 145.0
YHH2_k127_4525345_13 - - - - 0.0000000000000000000000000000000000213 139.0
YHH2_k127_4525345_14 RRXRR protein - - - 0.0000000000000000002331 90.0
YHH2_k127_4525345_15 Transposase - - - 0.00000000001892 67.0
YHH2_k127_4525345_16 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000418 49.0
YHH2_k127_4525345_17 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000004839 50.0
YHH2_k127_4525345_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 561.0
YHH2_k127_4525345_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 423.0
YHH2_k127_4525345_4 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 393.0
YHH2_k127_4525345_5 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 371.0
YHH2_k127_4525345_6 component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 354.0
YHH2_k127_4525345_7 Type I restriction-modification system methyltransferase subunit K03427 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 334.0
YHH2_k127_4525345_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000002807 228.0
YHH2_k127_4525345_9 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000007353 227.0
YHH2_k127_4591298_0 PFAM integrase family protein - - - 0.0000000000000000000000000000000000000000000007463 173.0
YHH2_k127_4591298_1 D5 N terminal like K06919 - - 0.0000000000000000000000000002131 121.0
YHH2_k127_4591298_2 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.000008758 48.0
YHH2_k127_4591298_3 Helix-turn-helix XRE-family like proteins - - - 0.00005114 50.0
YHH2_k127_4712302_0 D5 N terminal like K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 439.0
YHH2_k127_4712302_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 338.0
YHH2_k127_4712302_2 Endonuclease I K01150 - 3.1.21.1 0.0000000000000000000000000000000000000000000000000000000000000000003684 235.0
YHH2_k127_4712302_3 Helix-turn-helix domain K07729 - - 0.00003167 49.0
YHH2_k127_4931296_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1417.0
YHH2_k127_4931296_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1384.0
YHH2_k127_4931296_10 Lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 395.0
YHH2_k127_4931296_11 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 388.0
YHH2_k127_4931296_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 345.0
YHH2_k127_4931296_13 3'-5' exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 342.0
YHH2_k127_4931296_14 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 327.0
YHH2_k127_4931296_15 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000356 253.0
YHH2_k127_4931296_16 carboxymethylenebutenolidase activity K01061,K21105 - 3.1.1.102,3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000005478 256.0
YHH2_k127_4931296_17 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000008118 254.0
YHH2_k127_4931296_18 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000002203 222.0
YHH2_k127_4931296_19 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000001717 222.0
YHH2_k127_4931296_2 helicase activity - - - 0.0 1212.0
YHH2_k127_4931296_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000263 229.0
YHH2_k127_4931296_21 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000005746 220.0
YHH2_k127_4931296_23 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000000007639 192.0
YHH2_k127_4931296_24 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000000000000000003003 178.0
YHH2_k127_4931296_25 Domain of unknown function DUF29 - - - 0.00000000000000000000000000000000000000001497 159.0
YHH2_k127_4931296_26 protein conserved in bacteria - - - 0.000000000000000000000000000000001437 132.0
YHH2_k127_4931296_27 Addiction module toxin RelE StbE family - - - 0.000000000000000000000000000003046 121.0
YHH2_k127_4931296_28 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000001465 118.0
YHH2_k127_4931296_29 - - - - 0.00000000000000000000001147 102.0
YHH2_k127_4931296_3 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 7.088e-214 677.0
YHH2_k127_4931296_30 PFAM Helix-turn-helix - - - 0.0000000000000000000001364 102.0
YHH2_k127_4931296_31 Helix-turn-helix - - - 0.0000000000000000001281 93.0
YHH2_k127_4931296_32 protein conserved in bacteria - - - 0.0000000000000000008298 87.0
YHH2_k127_4931296_34 Extracellular nuclease K07004 - - 0.000000000000009431 87.0
YHH2_k127_4931296_35 - - - - 0.00000000001881 66.0
YHH2_k127_4931296_36 Membrane - - - 0.00000001227 68.0
YHH2_k127_4931296_4 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 7.533e-201 634.0
YHH2_k127_4931296_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 579.0
YHH2_k127_4931296_6 PFAM response regulator receiver K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 572.0
YHH2_k127_4931296_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 512.0
YHH2_k127_4931296_8 Eco57I restriction-modification methylase K07317 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 527.0
YHH2_k127_4931296_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 413.0
YHH2_k127_4960379_0 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 423.0
YHH2_k127_4960379_1 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 299.0
YHH2_k127_4989650_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10715 - 2.7.13.3 0.0 1438.0
YHH2_k127_4989650_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1047.0
YHH2_k127_4989650_10 Cyclic peptide transporter K06160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 361.0
YHH2_k127_4989650_11 HAD-superfamily hydrolase, subfamily IIB K00696,K07024 - 2.4.1.14,3.1.3.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
YHH2_k127_4989650_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001187 274.0
YHH2_k127_4989650_13 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000221 276.0
YHH2_k127_4989650_14 Diguanylate cyclase, GGDEF domain K20954 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000102 250.0
YHH2_k127_4989650_15 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000001728 236.0
YHH2_k127_4989650_16 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000003673 228.0
YHH2_k127_4989650_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000009665 226.0
YHH2_k127_4989650_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331,K05582 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000001633 226.0
YHH2_k127_4989650_19 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000701 198.0
YHH2_k127_4989650_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.717e-257 801.0
YHH2_k127_4989650_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000001307 167.0
YHH2_k127_4989650_21 protein domain associated with - - - 0.00000000000000000000000000000000000001641 150.0
YHH2_k127_4989650_22 protein domain associated with - - - 0.0000000000000000000000000000001154 136.0
YHH2_k127_4989650_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000005325 111.0
YHH2_k127_4989650_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 7.833e-254 800.0
YHH2_k127_4989650_4 PFAM Type II secretion system protein E K02454 - - 8.024e-206 650.0
YHH2_k127_4989650_5 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 565.0
YHH2_k127_4989650_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 525.0
YHH2_k127_4989650_7 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 524.0
YHH2_k127_4989650_8 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 473.0
YHH2_k127_4989650_9 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 380.0
YHH2_k127_5224056_0 Domain of unknown function (DUF4914) - - - 3.501e-280 872.0
YHH2_k127_5224056_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 496.0
YHH2_k127_5224056_10 Domain of Unknown Function (DUF928) - - - 0.0000000000000000003257 96.0
YHH2_k127_5224056_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 451.0
YHH2_k127_5224056_3 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 395.0
YHH2_k127_5224056_4 class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 350.0
YHH2_k127_5224056_5 biosynthesis protein K16710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002545 286.0
YHH2_k127_5224056_6 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006934 250.0
YHH2_k127_5224056_7 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000001035 245.0
YHH2_k127_5224056_8 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000000000000000003446 225.0
YHH2_k127_5224056_9 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000002474 221.0
YHH2_k127_54430_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.086e-263 817.0
YHH2_k127_54430_1 - - - - 6.043e-244 774.0
YHH2_k127_54430_10 OmpA family - - - 0.000000000000000000005482 100.0
YHH2_k127_54430_11 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000005159 83.0
YHH2_k127_54430_13 protein with SCP PR1 domains - - - 0.00000000005177 76.0
YHH2_k127_54430_2 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 454.0
YHH2_k127_54430_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 376.0
YHH2_k127_54430_4 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 352.0
YHH2_k127_54430_5 NADH dehydrogenase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001569 253.0
YHH2_k127_54430_6 Protein of unknown function (DUF2808) - - - 0.0000000000000000000000000000000000000000000000000000002616 207.0
YHH2_k127_54430_7 BioY family K03523 - - 0.0000000000000000000000000000000000000000001177 166.0
YHH2_k127_54430_8 TIGRFAM regulatory protein, FmdB family - - - 0.000000000000000000000000000000000000000001687 157.0
YHH2_k127_54430_9 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000897 145.0
YHH2_k127_5469637_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 4.993e-198 623.0
YHH2_k127_5469637_1 PFAM Type II IV secretion system protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 598.0
YHH2_k127_5469637_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000005728 156.0
YHH2_k127_5469637_11 protein acetylation - - - 0.0000000000000000000000000000000000005209 146.0
YHH2_k127_5469637_12 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000004307 77.0
YHH2_k127_5469637_13 - K06950 - - 0.0000004301 54.0
YHH2_k127_5469637_2 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 599.0
YHH2_k127_5469637_3 twitching motility protein PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 550.0
YHH2_k127_5469637_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 548.0
YHH2_k127_5469637_5 fad dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 363.0
YHH2_k127_5469637_6 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
YHH2_k127_5469637_7 - - - - 0.0000000000000000000000000000000000000000000000000000000002599 210.0
YHH2_k127_5469637_8 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000001504 206.0
YHH2_k127_5469637_9 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000003304 194.0
YHH2_k127_5556668_0 PFAM von Willebrand factor type A - - - 0.0 1082.0
YHH2_k127_5556668_1 Two component regulator propeller K19694 - - 9.367e-321 1032.0
YHH2_k127_5556668_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 437.0
YHH2_k127_5556668_11 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 404.0
YHH2_k127_5556668_12 Glycosyltransferase like family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 417.0
YHH2_k127_5556668_13 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 392.0
YHH2_k127_5556668_14 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 373.0
YHH2_k127_5556668_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 365.0
YHH2_k127_5556668_16 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 366.0
YHH2_k127_5556668_17 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 327.0
YHH2_k127_5556668_18 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 325.0
YHH2_k127_5556668_19 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 297.0
YHH2_k127_5556668_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.601e-243 755.0
YHH2_k127_5556668_20 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
YHH2_k127_5556668_21 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009677 274.0
YHH2_k127_5556668_22 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002735 260.0
YHH2_k127_5556668_23 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005134 261.0
YHH2_k127_5556668_24 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000002087 238.0
YHH2_k127_5556668_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001797 239.0
YHH2_k127_5556668_26 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
YHH2_k127_5556668_27 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000001776 218.0
YHH2_k127_5556668_28 PFAM Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000000000000000004947 205.0
YHH2_k127_5556668_29 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000001007 202.0
YHH2_k127_5556668_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 4.734e-222 704.0
YHH2_k127_5556668_30 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000006284 190.0
YHH2_k127_5556668_31 response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000004079 174.0
YHH2_k127_5556668_32 protein conserved in bacteria K09938 - - 0.000000000000000000000000000000000000000003642 169.0
YHH2_k127_5556668_33 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000131 142.0
YHH2_k127_5556668_34 Transglycosylase SLT domain - - - 0.000000000000000000000000000000003134 136.0
YHH2_k127_5556668_36 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000002331 74.0
YHH2_k127_5556668_38 serine-type aminopeptidase activity - - - 0.000000000009522 69.0
YHH2_k127_5556668_39 - - - - 0.00001652 56.0
YHH2_k127_5556668_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 2.738e-199 647.0
YHH2_k127_5556668_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 553.0
YHH2_k127_5556668_6 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 503.0
YHH2_k127_5556668_7 tRNA synthetases class I (E and Q), catalytic domain K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 503.0
YHH2_k127_5556668_8 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 476.0
YHH2_k127_5556668_9 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 475.0
YHH2_k127_5628503_0 methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 401.0
YHH2_k127_5628503_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000002697 184.0
YHH2_k127_5642923_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.375e-261 823.0
YHH2_k127_5642923_1 Gliding motility protein GldG - - - 1.302e-214 683.0
YHH2_k127_5642923_10 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000004646 182.0
YHH2_k127_5642923_11 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000005357 147.0
YHH2_k127_5642923_12 COGs COG5439 conserved - - - 0.000000000000000000000000001143 115.0
YHH2_k127_5642923_13 - - - - 0.00000000000000000000001076 102.0
YHH2_k127_5642923_14 Putative restriction endonuclease - - - 0.00000000008138 63.0
YHH2_k127_5642923_2 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 443.0
YHH2_k127_5642923_3 CcmB protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 383.0
YHH2_k127_5642923_4 Serine phosphatase RsbU, regulator of sigma subunit K07315,K07716,K17763 - 2.7.13.3,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 349.0
YHH2_k127_5642923_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 304.0
YHH2_k127_5642923_6 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
YHH2_k127_5642923_7 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000002103 238.0
YHH2_k127_5642923_8 - - - - 0.000000000000000000000000000000000000000000000000000006051 195.0
YHH2_k127_5642923_9 Clan AA aspartic protease K06985 - - 0.00000000000000000000000000000000000000000000000000002014 193.0
YHH2_k127_5731578_0 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.0 2296.0
YHH2_k127_5731578_1 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 544.0
YHH2_k127_5731578_10 - - - - 0.00000001358 59.0
YHH2_k127_5731578_11 PFAM Resolvase, N-terminal - - - 0.00000004255 55.0
YHH2_k127_5731578_2 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 460.0
YHH2_k127_5731578_3 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 470.0
YHH2_k127_5731578_4 Fe-S cluster K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 431.0
YHH2_k127_5731578_5 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 422.0
YHH2_k127_5731578_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 372.0
YHH2_k127_5731578_7 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 316.0
YHH2_k127_5731578_8 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001732 278.0
YHH2_k127_5731578_9 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000002667 227.0
YHH2_k127_5735600_0 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0 1021.0
YHH2_k127_5735600_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.595e-232 734.0
YHH2_k127_5735600_10 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 267.0
YHH2_k127_5735600_11 COGs COG5381 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001741 257.0
YHH2_k127_5735600_12 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000849 269.0
YHH2_k127_5735600_13 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001178 243.0
YHH2_k127_5735600_14 COGs COG5439 conserved - - - 0.000000000000000000000000000000000000000001967 158.0
YHH2_k127_5735600_15 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000001909 144.0
YHH2_k127_5735600_2 Polysaccharide biosynthesis protein - - - 5.901e-200 640.0
YHH2_k127_5735600_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 566.0
YHH2_k127_5735600_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 517.0
YHH2_k127_5735600_5 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 499.0
YHH2_k127_5735600_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 492.0
YHH2_k127_5735600_7 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 474.0
YHH2_k127_5735600_8 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 438.0
YHH2_k127_5735600_9 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 395.0
YHH2_k127_5920353_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 610.0
YHH2_k127_5920353_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 528.0
YHH2_k127_5920353_10 NMT1-like family K02051 - - 0.000000000000000000000000000000000000009651 158.0
YHH2_k127_5920353_11 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.00000000000000000000000000000000007425 138.0
YHH2_k127_5920353_12 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000000000000002163 130.0
YHH2_k127_5920353_13 - - - - 0.00000000000000000000000000000000306 130.0
YHH2_k127_5920353_14 endonuclease activity - - - 0.00000000000000000000000000000002797 126.0
YHH2_k127_5920353_15 - - - - 0.000000000000000000003022 94.0
YHH2_k127_5920353_16 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 - - 0.0000000000000000009006 88.0
YHH2_k127_5920353_17 Lysozyme inhibitor LprI - - - 0.0000000000000004263 85.0
YHH2_k127_5920353_18 - - - - 0.000000000000008846 76.0
YHH2_k127_5920353_19 phosphorelay sensor kinase activity K03406,K07675,K15011,K21696 - 2.7.13.3 0.000000000178 71.0
YHH2_k127_5920353_2 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 467.0
YHH2_k127_5920353_20 Domain of unknown function (DUF4160) - - - 0.00001643 49.0
YHH2_k127_5920353_21 - - - - 0.0001609 47.0
YHH2_k127_5920353_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 368.0
YHH2_k127_5920353_4 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 362.0
YHH2_k127_5920353_5 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 351.0
YHH2_k127_5920353_6 ROK family K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 337.0
YHH2_k127_5920353_7 PFAM Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000002165 223.0
YHH2_k127_5920353_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000003568 200.0
YHH2_k127_5920353_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000005926 206.0
YHH2_k127_5965619_0 Glycosyl transferases group 1 - - - 0.0 1155.0
YHH2_k127_5965619_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1120.0
YHH2_k127_5965619_12 TIGRFAM transposase, IS605 OrfB K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000002696 232.0
YHH2_k127_5965619_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000008826 226.0
YHH2_k127_5965619_14 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001369 209.0
YHH2_k127_5965619_15 PFAM Stage II sporulation E family protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000001458 183.0
YHH2_k127_5965619_16 Stage II sporulation protein E (SpoIIE) K07315 - 3.1.3.3 0.00000000000000000000000000000000003881 137.0
YHH2_k127_5965619_17 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000575 134.0
YHH2_k127_5965619_18 TIGRFAM transposase, IS605 OrfB K07496 - - 0.000000000000000001453 87.0
YHH2_k127_5965619_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.306e-289 907.0
YHH2_k127_5965619_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 5.075e-217 734.0
YHH2_k127_5965619_4 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 610.0
YHH2_k127_5965619_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 617.0
YHH2_k127_5965619_6 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 530.0
YHH2_k127_5965619_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 392.0
YHH2_k127_5965619_8 ABC transporter K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 347.0
YHH2_k127_5965619_9 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 347.0
YHH2_k127_5970023_0 COG3209 Rhs family protein K11021 - - 0.0 1314.0
YHH2_k127_5970023_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 9.14e-322 991.0
YHH2_k127_5970023_10 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 592.0
YHH2_k127_5970023_11 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008329 583.0
YHH2_k127_5970023_12 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 558.0
YHH2_k127_5970023_13 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 561.0
YHH2_k127_5970023_14 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 554.0
YHH2_k127_5970023_15 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 506.0
YHH2_k127_5970023_16 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 519.0
YHH2_k127_5970023_17 binding-protein-dependent transport systems inner membrane component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 475.0
YHH2_k127_5970023_18 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 462.0
YHH2_k127_5970023_19 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 458.0
YHH2_k127_5970023_2 COG3209 Rhs family protein K11021 - - 1.785e-296 979.0
YHH2_k127_5970023_20 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 455.0
YHH2_k127_5970023_21 Belongs to the UbiD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 466.0
YHH2_k127_5970023_22 Belongs to the N-Me-Phe pilin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 458.0
YHH2_k127_5970023_23 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 391.0
YHH2_k127_5970023_24 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 351.0
YHH2_k127_5970023_25 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 335.0
YHH2_k127_5970023_26 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 336.0
YHH2_k127_5970023_27 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 313.0
YHH2_k127_5970023_28 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 317.0
YHH2_k127_5970023_29 HAD-superfamily hydrolase subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 310.0
YHH2_k127_5970023_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.444e-268 834.0
YHH2_k127_5970023_30 TIGRFAM FimV C-terminal domain K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 330.0
YHH2_k127_5970023_31 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 300.0
YHH2_k127_5970023_32 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 307.0
YHH2_k127_5970023_33 Methyltransferase, chemotaxis proteins K00575,K13486 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 297.0
YHH2_k127_5970023_34 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 297.0
YHH2_k127_5970023_35 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001491 282.0
YHH2_k127_5970023_36 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 280.0
YHH2_k127_5970023_37 Type IV pili signal transduction protein PilI K02659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004379 270.0
YHH2_k127_5970023_38 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000973 275.0
YHH2_k127_5970023_39 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000396 262.0
YHH2_k127_5970023_4 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K02660 - - 1.174e-240 761.0
YHH2_k127_5970023_40 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003083 262.0
YHH2_k127_5970023_41 PFAM Response regulator receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001682 245.0
YHH2_k127_5970023_42 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001203 252.0
YHH2_k127_5970023_43 Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006542 230.0
YHH2_k127_5970023_44 COG3038 Cytochrome B561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000002992 222.0
YHH2_k127_5970023_45 PFAM Response regulator receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000000000000000003792 218.0
YHH2_k127_5970023_46 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000399 218.0
YHH2_k127_5970023_47 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000005264 205.0
YHH2_k127_5970023_48 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000002963 202.0
YHH2_k127_5970023_49 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000001563 196.0
YHH2_k127_5970023_5 response regulator receiver K02487,K06596 - - 1.874e-240 784.0
YHH2_k127_5970023_50 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000003996 181.0
YHH2_k127_5970023_51 4-hydroxybenzoate polyprenyltransferase K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000007191 186.0
YHH2_k127_5970023_52 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000003099 177.0
YHH2_k127_5970023_53 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000001743 164.0
YHH2_k127_5970023_54 OmpA family K03640 - - 0.00000000000000000000000000000000000000000004474 166.0
YHH2_k127_5970023_55 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000006348 170.0
YHH2_k127_5970023_56 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000958 164.0
YHH2_k127_5970023_57 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000001154 164.0
YHH2_k127_5970023_58 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000025 161.0
YHH2_k127_5970023_59 Domain of unknown function (DUF4160) - - - 0.000000000000000000000000000000000000000004844 154.0
YHH2_k127_5970023_6 Histidine kinase - - - 1.406e-238 749.0
YHH2_k127_5970023_60 6,7-dimethyl-8-ribityllumazine synthase K00794 - 2.5.1.78 0.0000000000000000000000000000000000000001812 153.0
YHH2_k127_5970023_61 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7 0.000000000000000000000000000000000000002597 149.0
YHH2_k127_5970023_62 addiction module antidote protein HigA K21498 - - 0.00000000000000000000000000000000003322 136.0
YHH2_k127_5970023_63 membrane-anchored protein - - - 0.00000000000000000000000000000000005898 139.0
YHH2_k127_5970023_64 Protein of unknown function DUF86 K07075 - - 0.00000000000000000000000000000001312 130.0
YHH2_k127_5970023_65 chemotaxis signal transduction protein K06598 - - 0.0000000000000000000000000000001589 128.0
YHH2_k127_5970023_66 - - - - 0.0000000000000000000000000000001623 134.0
YHH2_k127_5970023_67 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000006882 125.0
YHH2_k127_5970023_68 Belongs to the ompA family - - - 0.000000000000000000000000000006916 125.0
YHH2_k127_5970023_69 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000000001374 115.0
YHH2_k127_5970023_7 PBS lyase HEAT-like repeat - - - 8.788e-207 675.0
YHH2_k127_5970023_70 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000008708 108.0
YHH2_k127_5970023_71 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000387 105.0
YHH2_k127_5970023_72 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000004926 104.0
YHH2_k127_5970023_73 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000007085 111.0
YHH2_k127_5970023_74 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000003333 99.0
YHH2_k127_5970023_76 - - - - 0.00000000000000001098 91.0
YHH2_k127_5970023_77 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000002121 80.0
YHH2_k127_5970023_79 PFAM DNA polymerase beta domain protein region K07075 - - 0.0000000001505 65.0
YHH2_k127_5970023_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 584.0
YHH2_k127_5970023_80 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000009194 67.0
YHH2_k127_5970023_82 Beta-propeller repeat - - - 0.000001588 60.0
YHH2_k127_5970023_9 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 578.0
YHH2_k127_6141637_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 332.0
YHH2_k127_6141637_1 Polymorphic membrane protein Chlamydia - - - 0.000000000000000000000000000000000000000000002561 190.0
YHH2_k127_6141637_2 TIGRFAM RHS repeat-associated core domain - - - 0.000000000000000000000000000000000000000002991 180.0
YHH2_k127_6141637_3 - - - - 0.00000000000000000000000000000001285 137.0
YHH2_k127_6141637_4 Phage Tail Collar Domain - - - 0.0000000000000000000000000007558 116.0
YHH2_k127_6141637_5 AntA/AntB antirepressor K07741 - - 0.00000000000000000000000004045 115.0
YHH2_k127_6141637_6 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.000000000000000002901 100.0
YHH2_k127_6141637_7 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000002763 77.0
YHH2_k127_6141637_8 Putative transposase, YhgA-like - - - 0.000000000182 72.0
YHH2_k127_6141637_9 domain protein K01081,K01347,K07004,K13735,K17624,K20276 - 3.1.3.5,3.2.1.97,3.4.21.72 0.000002796 61.0
YHH2_k127_6320198_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2339.0
YHH2_k127_6320198_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.0 1335.0
YHH2_k127_6320198_10 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 445.0
YHH2_k127_6320198_11 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 408.0
YHH2_k127_6320198_12 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 399.0
YHH2_k127_6320198_13 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 394.0
YHH2_k127_6320198_14 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 359.0
YHH2_k127_6320198_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 340.0
YHH2_k127_6320198_16 Uncharacterised protein family (UPF0014) K02069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
YHH2_k127_6320198_17 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000001275 245.0
YHH2_k127_6320198_18 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000009566 238.0
YHH2_k127_6320198_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.00000000000000000000000000000000000000000000000000000000000001902 243.0
YHH2_k127_6320198_2 Beta propeller domain - - - 6.207e-262 842.0
YHH2_k127_6320198_20 PFAM GumN family protein K09973 - - 0.0000000000000000000000000000000000000000000000000000000000005822 222.0
YHH2_k127_6320198_21 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000006368 160.0
YHH2_k127_6320198_22 Part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000006413 154.0
YHH2_k127_6320198_23 Thioredoxin domain - - - 0.0000000000000000000000000001849 115.0
YHH2_k127_6320198_25 CHASE2 K01768 - 4.6.1.1 0.0000005412 60.0
YHH2_k127_6320198_26 - - - - 0.000000784 53.0
YHH2_k127_6320198_27 methyl-accepting chemotaxis protein K03406 - - 0.00000162 55.0
YHH2_k127_6320198_3 Belongs to the ABC transporter superfamily K02031,K02032 - - 7.109e-225 708.0
YHH2_k127_6320198_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.62e-216 686.0
YHH2_k127_6320198_5 Transposase, IS605 OrfB family K07496 - - 4.682e-212 662.0
YHH2_k127_6320198_6 PFAM von Willebrand factor type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 593.0
YHH2_k127_6320198_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 583.0
YHH2_k127_6320198_8 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 497.0
YHH2_k127_6320198_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 452.0
YHH2_k127_6382854_0 cytochrome C peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 531.0
YHH2_k127_6382854_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 338.0
YHH2_k127_6382854_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007288 273.0
YHH2_k127_6382854_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006609 254.0
YHH2_k127_6382854_4 PFAM Transglycosylase SLT domain - - - 0.0000000214 60.0
YHH2_k127_6598018_0 Histidine kinase K03320,K03406,K03407,K07315 - 2.7.13.3,3.1.3.3 0.0 1556.0
YHH2_k127_6598018_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1186.0
YHH2_k127_6598018_10 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 589.0
YHH2_k127_6598018_11 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 562.0
YHH2_k127_6598018_12 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 559.0
YHH2_k127_6598018_13 protein conserved in bacteria K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 561.0
YHH2_k127_6598018_14 Helicase conserved C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 590.0
YHH2_k127_6598018_15 general secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 552.0
YHH2_k127_6598018_16 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 545.0
YHH2_k127_6598018_17 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction K08482 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007623,GO:0008150,GO:0008152,GO:0009605,GO:0009649,GO:0009966,GO:0009987,GO:0010646,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0023051,GO:0036211,GO:0042752,GO:0042754,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0048511,GO:0048519,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0065007,GO:0070297,GO:0071704,GO:1901564,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 542.0
YHH2_k127_6598018_18 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 498.0
YHH2_k127_6598018_19 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 488.0
YHH2_k127_6598018_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1019.0
YHH2_k127_6598018_20 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 480.0
YHH2_k127_6598018_21 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 490.0
YHH2_k127_6598018_22 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 498.0
YHH2_k127_6598018_23 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 477.0
YHH2_k127_6598018_24 transport system, permease component K13895 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 473.0
YHH2_k127_6598018_25 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 456.0
YHH2_k127_6598018_26 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 451.0
YHH2_k127_6598018_27 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 459.0
YHH2_k127_6598018_28 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 434.0
YHH2_k127_6598018_29 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 436.0
YHH2_k127_6598018_3 ATP:ADP antiporter activity - - - 1.477e-290 920.0
YHH2_k127_6598018_30 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 428.0
YHH2_k127_6598018_31 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 395.0
YHH2_k127_6598018_32 photoreceptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 381.0
YHH2_k127_6598018_33 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 353.0
YHH2_k127_6598018_34 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 338.0
YHH2_k127_6598018_35 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 342.0
YHH2_k127_6598018_36 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 323.0
YHH2_k127_6598018_37 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 302.0
YHH2_k127_6598018_38 PFAM glycosyl transferase family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 312.0
YHH2_k127_6598018_39 Phage shock protein A K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 291.0
YHH2_k127_6598018_4 Belongs to the 5'-nucleotidase family K17224 - - 1.422e-272 848.0
YHH2_k127_6598018_40 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 290.0
YHH2_k127_6598018_41 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 293.0
YHH2_k127_6598018_42 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007631 285.0
YHH2_k127_6598018_43 lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007774 282.0
YHH2_k127_6598018_44 Protein of unknown function (DUF3223) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008154 270.0
YHH2_k127_6598018_45 (Lipo)protein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002773 260.0
YHH2_k127_6598018_46 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000172 248.0
YHH2_k127_6598018_47 Bacterial transferase hexapeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000002111 239.0
YHH2_k127_6598018_48 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000671 240.0
YHH2_k127_6598018_49 cyclic nucleotide binding K01999,K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000003983 233.0
YHH2_k127_6598018_5 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.003e-267 829.0
YHH2_k127_6598018_50 (C AC39) subunit K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000007323 237.0
YHH2_k127_6598018_51 Bacterial protein of unknown function (DUF945) - - - 0.00000000000000000000000000000000000000000000000000000000000000001807 244.0
YHH2_k127_6598018_52 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000003186 233.0
YHH2_k127_6598018_53 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000006042 222.0
YHH2_k127_6598018_54 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000002969 238.0
YHH2_k127_6598018_55 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000001446 214.0
YHH2_k127_6598018_56 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000003812 211.0
YHH2_k127_6598018_57 response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000002275 200.0
YHH2_k127_6598018_58 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000001927 192.0
YHH2_k127_6598018_59 SMART Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000002032 186.0
YHH2_k127_6598018_6 Male sterility - - - 7.577e-261 818.0
YHH2_k127_6598018_60 - - - - 0.00000000000000000000000000000000000000000000000002212 201.0
YHH2_k127_6598018_61 protein conserved in bacteria K09980 - - 0.0000000000000000000000000000000000000000000000002891 180.0
YHH2_k127_6598018_62 cellulase activity - - - 0.000000000000000000000000000000000000000000000002014 192.0
YHH2_k127_6598018_63 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000596 181.0
YHH2_k127_6598018_64 polysaccharide export K01991,K20988 - - 0.00000000000000000000000000000000000000000000002161 183.0
YHH2_k127_6598018_65 - - - - 0.00000000000000000000000000000000000000000000402 165.0
YHH2_k127_6598018_66 Belongs to the HSP15 family K04762 - - 0.000000000000000000000000000000000001191 142.0
YHH2_k127_6598018_67 nucleic-acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000000001782 142.0
YHH2_k127_6598018_68 - - - - 0.000000000000000000000000000000001226 138.0
YHH2_k127_6598018_69 InterPro IPR007367 - - - 0.00000000000000000000000000000002347 128.0
YHH2_k127_6598018_7 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 8.133e-217 677.0
YHH2_k127_6598018_70 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000003142 127.0
YHH2_k127_6598018_71 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000000005076 109.0
YHH2_k127_6598018_72 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000354 97.0
YHH2_k127_6598018_73 - - - - 0.000000000000000001191 96.0
YHH2_k127_6598018_74 Lysozyme inhibitor LprI - - - 0.000000000000000001331 97.0
YHH2_k127_6598018_75 - - - - 0.00000000000000001083 87.0
YHH2_k127_6598018_76 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000002055 86.0
YHH2_k127_6598018_77 Protein of unknown function (DUF1284) K09706 - - 0.00000000000001648 83.0
YHH2_k127_6598018_78 - - - - 0.00000000000001966 85.0
YHH2_k127_6598018_79 PFAM KaiB domain K08481 - - 0.0000000000000871 75.0
YHH2_k127_6598018_8 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.791e-213 669.0
YHH2_k127_6598018_81 BRO family, N-terminal domain - - - 0.000000000006571 74.0
YHH2_k127_6598018_82 Pfam:DUF1311 - - - 0.0000000003253 71.0
YHH2_k127_6598018_83 BRO family, N-terminal domain - - - 0.000000002536 63.0
YHH2_k127_6598018_84 - - - - 0.00000002463 58.0
YHH2_k127_6598018_85 PFAM transposase IS605 OrfB K07496 - - 0.000001907 53.0
YHH2_k127_6598018_86 Lrp/AsnC ligand binding domain - - - 0.000004217 51.0
YHH2_k127_6598018_88 Probable transposase K07496 - - 0.0005045 47.0
YHH2_k127_6598018_89 - - - - 0.0007678 48.0
YHH2_k127_6598018_9 protein involved in exopolysaccharide biosynthesis K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 617.0
YHH2_k127_6605172_0 His Kinase A (phosphoacceptor) domain - - - 3.602e-253 799.0
YHH2_k127_6605172_1 Domain of Unknown Function (DUF349) - - - 9.977e-236 762.0
YHH2_k127_6605172_10 HPr Serine kinase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
YHH2_k127_6605172_11 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 380.0
YHH2_k127_6605172_12 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 294.0
YHH2_k127_6605172_13 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000016 259.0
YHH2_k127_6605172_14 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000006454 209.0
YHH2_k127_6605172_15 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000000000000000000000000000001175 209.0
YHH2_k127_6605172_16 Domain of unknown function DUF29 - - - 0.0000000000000000000000000000000000000000000000000000004875 196.0
YHH2_k127_6605172_17 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000002113 185.0
YHH2_k127_6605172_18 Protein of unknown function (DUF98) K03181 - 4.1.3.40 0.000000000000000000000000000000000000000007524 161.0
YHH2_k127_6605172_19 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001852 160.0
YHH2_k127_6605172_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 518.0
YHH2_k127_6605172_20 identical protein binding - - - 0.00000000000000000000000001097 124.0
YHH2_k127_6605172_21 - - - - 0.00000000000000000000001542 106.0
YHH2_k127_6605172_22 PFAM plasmid K06218 - - 0.0000000000000000000002282 100.0
YHH2_k127_6605172_23 Phosphopantetheine attachment site - - - 0.00000000000000002358 84.0
YHH2_k127_6605172_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000003652 55.0
YHH2_k127_6605172_3 NmrA-like family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 499.0
YHH2_k127_6605172_4 amidinotransferase K00613 - 2.1.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 467.0
YHH2_k127_6605172_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 433.0
YHH2_k127_6605172_6 Transposase, IS605 OrfB family K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 422.0
YHH2_k127_6605172_7 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 394.0
YHH2_k127_6605172_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 387.0
YHH2_k127_6605172_9 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 396.0
YHH2_k127_6857100_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1014.0
YHH2_k127_6857100_1 Cytochrome c - - - 4.208e-228 713.0
YHH2_k127_6857100_10 PFAM Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 392.0
YHH2_k127_6857100_11 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 373.0
YHH2_k127_6857100_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 359.0
YHH2_k127_6857100_13 3-phytase (Myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 349.0
YHH2_k127_6857100_14 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 312.0
YHH2_k127_6857100_15 negative regulation of glucose mediated signaling pathway K01120 GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0006139,GO:0006163,GO:0006195,GO:0006198,GO:0006469,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009187,GO:0009214,GO:0009259,GO:0009261,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010563,GO:0010605,GO:0010646,GO:0010648,GO:0016787,GO:0016788,GO:0018130,GO:0019220,GO:0019222,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0023051,GO:0023057,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042325,GO:0042326,GO:0042578,GO:0043086,GO:0043549,GO:0043949,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0045859,GO:0045936,GO:0046058,GO:0046068,GO:0046069,GO:0046434,GO:0046483,GO:0046700,GO:0047555,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0055086,GO:0060255,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071900,GO:0071901,GO:0072521,GO:0072523,GO:0080090,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1902531,GO:1902659,GO:1902660,GO:2000479,GO:2000480 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 300.0
YHH2_k127_6857100_16 Receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 312.0
YHH2_k127_6857100_17 TIGRFAM TIGR00266 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
YHH2_k127_6857100_18 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003564 283.0
YHH2_k127_6857100_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 4.009e-224 710.0
YHH2_k127_6857100_20 phosphorelay sensor kinase activity K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000538 272.0
YHH2_k127_6857100_21 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000001435 226.0
YHH2_k127_6857100_22 Pfam OmpA - - - 0.00000000000000000000000000000000000000000000000000000000002817 221.0
YHH2_k127_6857100_23 secreted protein - - - 0.0000000000000000000000000000000000000000000000001744 186.0
YHH2_k127_6857100_24 protein transport across the cell outer membrane K02452 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000002212 187.0
YHH2_k127_6857100_25 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000005454 171.0
YHH2_k127_6857100_26 CHAT domain - - - 0.0000000000000000000000000000000000000000002681 165.0
YHH2_k127_6857100_27 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000008801 178.0
YHH2_k127_6857100_28 paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000001144 130.0
YHH2_k127_6857100_29 Pfam cytochrome c - - - 0.00000000000000000000000000002065 120.0
YHH2_k127_6857100_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 6.584e-220 692.0
YHH2_k127_6857100_30 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.000000000000000000000000000031 130.0
YHH2_k127_6857100_31 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000008547 110.0
YHH2_k127_6857100_32 PspA/IM30 family K03969 - - 0.00000000000000000001034 99.0
YHH2_k127_6857100_33 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.0000000000004701 70.0
YHH2_k127_6857100_34 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000001218 81.0
YHH2_k127_6857100_35 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000147 76.0
YHH2_k127_6857100_36 Outer membrane efflux protein - - - 0.000000002177 59.0
YHH2_k127_6857100_4 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 579.0
YHH2_k127_6857100_5 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 558.0
YHH2_k127_6857100_6 Type II secretory pathway, component PulD K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 551.0
YHH2_k127_6857100_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 495.0
YHH2_k127_6857100_8 Restriction endonuclease K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 449.0
YHH2_k127_6857100_9 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 434.0
YHH2_k127_6900572_0 AMP-binding enzyme C-terminal domain K01897 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006644,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009898,GO:0009987,GO:0015645,GO:0016020,GO:0016042,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0030258,GO:0031406,GO:0032787,GO:0033293,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0036041,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046395,GO:0046483,GO:0050896,GO:0051186,GO:0055086,GO:0055114,GO:0070538,GO:0071704,GO:0071944,GO:0072329,GO:0072521,GO:0090407,GO:0098552,GO:0098562,GO:1901135,GO:1901360,GO:1901564,GO:1901575,GO:1901576 6.2.1.3 5.169e-241 755.0
YHH2_k127_6900572_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 534.0
YHH2_k127_6900572_10 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 258.0
YHH2_k127_6900572_11 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000378 251.0
YHH2_k127_6900572_13 chlorophyll binding K21449 - - 0.0000000000000000000000000000000000000000000000000000009966 201.0
YHH2_k127_6900572_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000001856 183.0
YHH2_k127_6900572_15 - - - - 0.00000000000000000000000000000000000000000000006715 177.0
YHH2_k127_6900572_16 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000001048 144.0
YHH2_k127_6900572_17 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000005563 145.0
YHH2_k127_6900572_18 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000007695 109.0
YHH2_k127_6900572_19 PFAM Resolvase, N-terminal - - - 0.0000001525 54.0
YHH2_k127_6900572_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 539.0
YHH2_k127_6900572_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 524.0
YHH2_k127_6900572_4 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 469.0
YHH2_k127_6900572_5 50S ribosome-binding GTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 430.0
YHH2_k127_6900572_6 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 405.0
YHH2_k127_6900572_7 CBS domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 354.0
YHH2_k127_6900572_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 334.0
YHH2_k127_6900572_9 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 314.0
YHH2_k127_7396496_0 2 iron, 2 sulfur cluster binding - - - 0.0 1330.0
YHH2_k127_7396496_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1283.0
YHH2_k127_7396496_10 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 404.0
YHH2_k127_7396496_11 undecaprenyl-phosphate glucose phosphotransferase activity K05946,K13657,K13660,K21303 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016780,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046402,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.187,2.4.1.252,2.7.8.40 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
YHH2_k127_7396496_12 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000006984 249.0
YHH2_k127_7396496_13 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000002105 179.0
YHH2_k127_7396496_14 Outer membrane lipoprotein K06077 - - 0.000000000000000000000000000000000000000000000001399 178.0
YHH2_k127_7396496_15 PFAM peptidase - - - 0.00000000000000000000000000000000000000000002392 175.0
YHH2_k127_7396496_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000000000000000000000000005469 149.0
YHH2_k127_7396496_17 TIGRFAM Phosphotransferase System HPr (HPr) Family K11189 - - 0.0000000000000000000000000000001048 127.0
YHH2_k127_7396496_18 nodulation - - - 0.00000000000000000000000000004541 120.0
YHH2_k127_7396496_19 - - - - 0.00000000000000000381 84.0
YHH2_k127_7396496_2 response regulator - - - 6.435e-235 732.0
YHH2_k127_7396496_20 pathogenesis - - - 0.0000000000002636 85.0
YHH2_k127_7396496_21 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000005928 70.0
YHH2_k127_7396496_22 Protein of unknown function (DUF721) - - - 0.0000000001517 67.0
YHH2_k127_7396496_23 - - - - 0.000006736 51.0
YHH2_k127_7396496_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.112e-233 736.0
YHH2_k127_7396496_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.516e-231 720.0
YHH2_k127_7396496_5 PFAM Pyridoxal-dependent decarboxylase K01580 - 4.1.1.15 8.111e-229 721.0
YHH2_k127_7396496_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 577.0
YHH2_k127_7396496_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 466.0
YHH2_k127_7396496_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 462.0
YHH2_k127_7396496_9 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 462.0
YHH2_k127_7429801_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.351e-241 752.0
YHH2_k127_7429801_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 338.0
YHH2_k127_7429801_10 - - - - 0.0000004986 51.0
YHH2_k127_7429801_2 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 292.0
YHH2_k127_7429801_3 PFAM Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004769 275.0
YHH2_k127_7429801_4 PFAM Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000003836 203.0
YHH2_k127_7429801_5 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000001042 120.0
YHH2_k127_7429801_6 mRNA binding K07339 - - 0.000000000000000000000006819 101.0
YHH2_k127_7429801_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000001824 93.0
YHH2_k127_7450675_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.577e-288 896.0
YHH2_k127_7450675_1 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 479.0
YHH2_k127_7450675_10 - - - - 0.00000000000000000000000000000001469 146.0
YHH2_k127_7450675_12 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000002867 131.0
YHH2_k127_7450675_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000003912 126.0
YHH2_k127_7450675_14 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000002978 109.0
YHH2_k127_7450675_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000001341 105.0
YHH2_k127_7450675_16 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000001523 113.0
YHH2_k127_7450675_17 - - - - 0.00000000000000000001416 109.0
YHH2_k127_7450675_18 - - - - 0.0000008795 59.0
YHH2_k127_7450675_19 - - - - 0.000002012 55.0
YHH2_k127_7450675_2 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 449.0
YHH2_k127_7450675_3 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 425.0
YHH2_k127_7450675_4 Protein of unknown function (DUF1566) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 383.0
YHH2_k127_7450675_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003723 290.0
YHH2_k127_7450675_6 protein conserved in cyanobacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001111 261.0
YHH2_k127_7450675_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000002049 225.0
YHH2_k127_7450675_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000005354 140.0
YHH2_k127_7450675_9 Psort location Extracellular, score 9.64 - - - 0.00000000000000000000000000000000006016 156.0
YHH2_k127_7455680_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 6.6e-287 893.0
YHH2_k127_7455680_1 Histidine kinase - - - 1.669e-286 931.0
YHH2_k127_7455680_10 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 599.0
YHH2_k127_7455680_11 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 562.0
YHH2_k127_7455680_12 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 534.0
YHH2_k127_7455680_13 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 555.0
YHH2_k127_7455680_14 PFAM Protein kinase domain K00384,K03407,K11527 - 1.8.1.9,2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 570.0
YHH2_k127_7455680_15 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 512.0
YHH2_k127_7455680_16 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 491.0
YHH2_k127_7455680_17 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 474.0
YHH2_k127_7455680_18 Forkhead associated domain K00870,K12132 - 2.7.1.37,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 451.0
YHH2_k127_7455680_19 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 443.0
YHH2_k127_7455680_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.785e-282 874.0
YHH2_k127_7455680_20 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 420.0
YHH2_k127_7455680_21 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 433.0
YHH2_k127_7455680_22 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 367.0
YHH2_k127_7455680_23 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 353.0
YHH2_k127_7455680_24 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 349.0
YHH2_k127_7455680_25 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 343.0
YHH2_k127_7455680_26 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 336.0
YHH2_k127_7455680_27 sulfite reductase K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 327.0
YHH2_k127_7455680_28 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 319.0
YHH2_k127_7455680_29 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 316.0
YHH2_k127_7455680_3 4Fe-4S dicluster domain - - - 1.799e-271 841.0
YHH2_k127_7455680_30 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 311.0
YHH2_k127_7455680_31 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 291.0
YHH2_k127_7455680_32 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002654 276.0
YHH2_k127_7455680_33 Methyltransferase type 11 K00570 - 2.1.1.17,2.1.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000004549 250.0
YHH2_k127_7455680_34 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006744 239.0
YHH2_k127_7455680_35 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000000008006 229.0
YHH2_k127_7455680_36 TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000004884 229.0
YHH2_k127_7455680_37 PFAM L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000001852 222.0
YHH2_k127_7455680_38 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000000000000000000002039 218.0
YHH2_k127_7455680_39 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000000000629 203.0
YHH2_k127_7455680_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.773e-264 829.0
YHH2_k127_7455680_40 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000001455 190.0
YHH2_k127_7455680_41 protein serine/threonine phosphatase activity K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000001645 188.0
YHH2_k127_7455680_42 general secretion pathway protein K02456 - - 0.0000000000000000000000000000000000000000000000004363 179.0
YHH2_k127_7455680_43 Belongs to the DsrF TusC family K07236 - - 0.00000000000000000000000000000000000000000000003161 173.0
YHH2_k127_7455680_44 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000003074 166.0
YHH2_k127_7455680_45 PFAM PilZ domain K02676 - - 0.0000000000000000000000000000000000000009973 150.0
YHH2_k127_7455680_46 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000002701 135.0
YHH2_k127_7455680_48 DsrH like protein K07237 - - 0.000000000000000000000000000000007544 129.0
YHH2_k127_7455680_49 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000008624 128.0
YHH2_k127_7455680_5 Phosphoglycerol transferase - - - 6.508e-232 733.0
YHH2_k127_7455680_50 Modulates RecA activity K03565 - - 0.000000000000000000000000000005762 124.0
YHH2_k127_7455680_51 - - - - 0.00000000000000000000000006594 114.0
YHH2_k127_7455680_53 VanZ like family - - - 0.00000000000000000000001069 104.0
YHH2_k127_7455680_54 - - - - 0.0000000000000000002893 91.0
YHH2_k127_7455680_55 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000004773 76.0
YHH2_k127_7455680_56 Domain of unknown function (DUF4351) - - - 0.00000000002421 65.0
YHH2_k127_7455680_58 - - - - 0.0000000009289 61.0
YHH2_k127_7455680_6 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 8.579e-221 696.0
YHH2_k127_7455680_7 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K11181 - 1.8.99.5 1.139e-213 665.0
YHH2_k127_7455680_8 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 608.0
YHH2_k127_7455680_9 Spermidine putrescine-binding periplasmic protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 579.0
YHH2_k127_7562063_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.358e-279 865.0
YHH2_k127_7562063_1 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 547.0
YHH2_k127_7562063_10 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 304.0
YHH2_k127_7562063_11 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 296.0
YHH2_k127_7562063_12 PFAM Leucine Rich Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 304.0
YHH2_k127_7562063_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 316.0
YHH2_k127_7562063_14 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006752 261.0
YHH2_k127_7562063_15 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000008321 238.0
YHH2_k127_7562063_16 PFAM Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000003439 224.0
YHH2_k127_7562063_17 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000002941 226.0
YHH2_k127_7562063_18 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000007296 195.0
YHH2_k127_7562063_19 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000001024 162.0
YHH2_k127_7562063_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 489.0
YHH2_k127_7562063_20 Lysophospholipase l1-like esterase - - - 0.0000000000000000000000000000001953 133.0
YHH2_k127_7562063_21 protein conserved in bacteria - - - 0.0000000000000000000000002487 118.0
YHH2_k127_7562063_22 Integral membrane protein (DUF2244) - - - 0.000000000000000000000001207 109.0
YHH2_k127_7562063_23 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000001481 94.0
YHH2_k127_7562063_24 aminopeptidase activity K07004 - - 0.000000001132 70.0
YHH2_k127_7562063_3 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000751 475.0
YHH2_k127_7562063_4 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 462.0
YHH2_k127_7562063_5 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 452.0
YHH2_k127_7562063_6 Membrane bound O-acyl transferase, MBOAT family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 453.0
YHH2_k127_7562063_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 441.0
YHH2_k127_7562063_8 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 364.0
YHH2_k127_7562063_9 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 362.0
YHH2_k127_759120_0 Penicillin-Binding Protein C-terminus Family - - - 6.582e-294 918.0
YHH2_k127_759120_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.278e-247 782.0
YHH2_k127_759120_10 hemerythrin-like metal-binding K07216 - - 0.0000000000000000000000000000000000000000000000000000006969 196.0
YHH2_k127_759120_11 Domain of unknown function DUF29 - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
YHH2_k127_759120_12 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000005249 146.0
YHH2_k127_759120_13 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000004042 130.0
YHH2_k127_759120_14 PilZ domain - - - 0.0000000000000000007229 91.0
YHH2_k127_759120_2 Heat shock 70 kDa protein K04043 - - 3.49e-218 681.0
YHH2_k127_759120_3 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 518.0
YHH2_k127_759120_4 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 407.0
YHH2_k127_759120_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 408.0
YHH2_k127_759120_6 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 402.0
YHH2_k127_759120_7 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 389.0
YHH2_k127_759120_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000006608 233.0
YHH2_k127_759120_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000001809 213.0
YHH2_k127_7725415_0 WD domain, G-beta repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 347.0
YHH2_k127_7725415_1 Transposase - - - 0.0000000003744 61.0
YHH2_k127_7725415_2 - - - - 0.000000002715 58.0
YHH2_k127_7738534_0 Large extracellular alpha-helical protein K06894 - - 0.0 2214.0
YHH2_k127_7738534_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.114e-287 888.0
YHH2_k127_7738534_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 383.0
YHH2_k127_7738534_11 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
YHH2_k127_7738534_12 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 313.0
YHH2_k127_7738534_13 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007269 269.0
YHH2_k127_7738534_14 Peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000007414 268.0
YHH2_k127_7738534_15 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000107 239.0
YHH2_k127_7738534_16 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000000008083 207.0
YHH2_k127_7738534_17 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000001252 211.0
YHH2_k127_7738534_18 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000002054 192.0
YHH2_k127_7738534_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000003144 192.0
YHH2_k127_7738534_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 9.54e-263 814.0
YHH2_k127_7738534_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000000002083 154.0
YHH2_k127_7738534_21 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000000000000000000004098 147.0
YHH2_k127_7738534_22 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000003595 130.0
YHH2_k127_7738534_23 ATP synthase I chain K02116 - - 0.000000000000000000000000000000004406 132.0
YHH2_k127_7738534_24 - - - - 0.0000000000000000000000000000001575 124.0
YHH2_k127_7738534_25 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000003435 117.0
YHH2_k127_7738534_26 sequence-specific DNA binding K07467 - - 0.00000000000000000000000000006936 123.0
YHH2_k127_7738534_27 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000003795 111.0
YHH2_k127_7738534_28 YoeB-like toxin of bacterial type II toxin-antitoxin system K19158 - - 0.0000000000000000000000001398 106.0
YHH2_k127_7738534_29 Excalibur calcium-binding domain - - - 0.0000000000000000000000008831 106.0
YHH2_k127_7738534_3 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 611.0
YHH2_k127_7738534_30 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000003057 103.0
YHH2_k127_7738534_31 mRNA binding - - - 0.0000000000000005078 79.0
YHH2_k127_7738534_32 toxin-antitoxin pair type II binding K08591,K19159 - 2.3.1.15 0.000000000000002393 78.0
YHH2_k127_7738534_33 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000927 76.0
YHH2_k127_7738534_34 guanyl-nucleotide exchange factor activity K01387,K07114,K12287 - 3.4.24.3 0.00000000000009133 83.0
YHH2_k127_7738534_36 - - - - 0.0000000001991 64.0
YHH2_k127_7738534_37 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000002353 68.0
YHH2_k127_7738534_38 TIGRFAM addiction module toxin, RelE StbE family K06218 - - 0.00001369 49.0
YHH2_k127_7738534_39 cysteine-type peptidase activity - - - 0.0008269 51.0
YHH2_k127_7738534_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 620.0
YHH2_k127_7738534_5 secondary active sulfate transmembrane transporter activity K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 455.0
YHH2_k127_7738534_6 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 467.0
YHH2_k127_7738534_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 411.0
YHH2_k127_7738534_8 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 402.0
YHH2_k127_7738534_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 390.0
YHH2_k127_7811316_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 2.5e-321 1016.0
YHH2_k127_7811316_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 4.092e-285 890.0
YHH2_k127_7811316_10 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000001112 241.0
YHH2_k127_7811316_11 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000005711 231.0
YHH2_k127_7811316_12 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000363 215.0
YHH2_k127_7811316_13 LemA family - - - 0.0000000000000000000000000000000000000000000000000002576 194.0
YHH2_k127_7811316_14 Belongs to the globin family K05916 - 1.14.12.17 0.00000000000000000000000000000000000000000001906 165.0
YHH2_k127_7811316_15 Domain of unknown function (DUF4214) - - - 0.000000000000000000000000000000000000000001138 183.0
YHH2_k127_7811316_16 biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000007007 158.0
YHH2_k127_7811316_17 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000000000000000000000000000000000002265 155.0
YHH2_k127_7811316_18 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.000000000000000000000000000003027 128.0
YHH2_k127_7811316_19 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.000000000002899 82.0
YHH2_k127_7811316_2 ion channel K05802 - - 1.182e-208 684.0
YHH2_k127_7811316_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 425.0
YHH2_k127_7811316_4 Glycosyl Transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 407.0
YHH2_k127_7811316_5 PFAM short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 319.0
YHH2_k127_7811316_6 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 301.0
YHH2_k127_7811316_7 Domain of unknown function DUF11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 324.0
YHH2_k127_7811316_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 286.0
YHH2_k127_7811316_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003435 270.0
YHH2_k127_8185878_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 417.0
YHH2_k127_8185878_1 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000000001497 133.0
YHH2_k127_8185878_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000002224 116.0
YHH2_k127_8325102_0 GTP-binding protein TypA K06207 - - 4.335e-306 946.0
YHH2_k127_8325102_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.396e-301 947.0
YHH2_k127_8325102_10 Sulfatase-modifying factor enzyme 1 K20333 - - 0.000000000000000000000000000000000000000000000000000000000001037 242.0
YHH2_k127_8325102_11 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000001904 204.0
YHH2_k127_8325102_12 PFAM Sulphatase-modifying factor - - - 0.000000000000000000000000000000000000000000000000000001299 222.0
YHH2_k127_8325102_13 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000000000000000000006243 185.0
YHH2_k127_8325102_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000008827 169.0
YHH2_k127_8325102_15 phosphatase, C-terminal domain of histone macro H2A1 like protein - - - 0.0000000000000000000000000000000000000000002215 185.0
YHH2_k127_8325102_16 DDE superfamily endonuclease K07494 - - 0.0000000000000000000000000000000001053 142.0
YHH2_k127_8325102_17 membrane - - - 0.000000000000008309 80.0
YHH2_k127_8325102_18 PFAM Transposase, Synechocystis PCC 6803 K07494 - - 0.0000000001685 66.0
YHH2_k127_8325102_2 diguanylate cyclase (GGDEF) domain K21025 - - 2.272e-272 853.0
YHH2_k127_8325102_3 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 483.0
YHH2_k127_8325102_4 SPFH Band 7 PHB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 445.0
YHH2_k127_8325102_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 408.0
YHH2_k127_8325102_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 402.0
YHH2_k127_8325102_7 protein with protein kinase and helix-hairpin-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001042 308.0
YHH2_k127_8325102_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001199 275.0
YHH2_k127_8325102_9 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000005219 216.0
YHH2_k127_8404114_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1219.0
YHH2_k127_8404114_1 Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 607.0
YHH2_k127_8404114_10 pathogenesis - - - 0.0000000000000000000000000000000005202 152.0
YHH2_k127_8404114_11 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000001353 134.0
YHH2_k127_8404114_12 Helix-turn-helix domain - - - 0.00000000000000000000000000001417 129.0
YHH2_k127_8404114_13 F5/8 type C domain - - - 0.0000000000000000000000000005958 132.0
YHH2_k127_8404114_15 Protein of unknown function (DUF465) - - - 0.00000000000000000000008727 99.0
YHH2_k127_8404114_16 InterPro IPR003367 - - - 0.00000000000000004069 96.0
YHH2_k127_8404114_17 cellulose binding K15924 - 3.2.1.136 0.00000000001799 78.0
YHH2_k127_8404114_18 - - - - 0.000000003462 70.0
YHH2_k127_8404114_19 Helix-turn-helix - - - 0.00008771 53.0
YHH2_k127_8404114_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 405.0
YHH2_k127_8404114_20 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.0006291 42.0
YHH2_k127_8404114_3 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 358.0
YHH2_k127_8404114_4 N-Acetylmuramoyl-L-alanine amidase K01447,K03806,K11066 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 324.0
YHH2_k127_8404114_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 286.0
YHH2_k127_8404114_6 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003566 293.0
YHH2_k127_8404114_7 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000001292 243.0
YHH2_k127_8404114_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000436 239.0
YHH2_k127_8404114_9 nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000002598 203.0
YHH2_k127_8421479_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1852.0
YHH2_k127_8421479_1 RNB K01147 - 3.1.13.1 3.721e-242 766.0
YHH2_k127_8421479_10 Domain of unknown function (DUF697) K08990 - - 0.000000000000000000000000000000000000000000000000000000001321 214.0
YHH2_k127_8421479_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000005555 197.0
YHH2_k127_8421479_12 Protein of unknown function (DUF779) K09959 - - 0.0000000000000000000000000000000000000000000000000002973 186.0
YHH2_k127_8421479_13 Protein of unknown function (DUF2970) - - - 0.000000000000007078 77.0
YHH2_k127_8421479_2 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 6.379e-200 629.0
YHH2_k127_8421479_3 YcjX-like family, DUF463 K06918 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 497.0
YHH2_k127_8421479_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 436.0
YHH2_k127_8421479_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 422.0
YHH2_k127_8421479_6 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 403.0
YHH2_k127_8421479_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 397.0
YHH2_k127_8421479_8 TIGRFAM Serine O-acetyltransferase K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009314,GO:0009333,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 349.0
YHH2_k127_8421479_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 303.0
YHH2_k127_8422863_0 metallopeptidase activity K01113,K09607 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 580.0
YHH2_k127_8422863_1 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 370.0
YHH2_k127_8422863_2 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 308.0
YHH2_k127_8422863_3 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 307.0
YHH2_k127_8422863_4 Domain of unknown function (DUF4381) - - - 0.000000000000000000000000000000000000009791 151.0
YHH2_k127_8422863_5 Pfam Tetratricopeptide K07114 - - 0.00000000000000000000000000000000004153 153.0
YHH2_k127_8547253_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1125.0
YHH2_k127_8547253_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1065.0
YHH2_k127_8547253_10 Ras of Complex, Roc, domain of DAPkinase K06883 - - 6.606e-196 638.0
YHH2_k127_8547253_11 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 588.0
YHH2_k127_8547253_12 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 557.0
YHH2_k127_8547253_13 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 541.0
YHH2_k127_8547253_14 PFAM DNA methylase N-4 N-6 domain protein K07319 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 493.0
YHH2_k127_8547253_15 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 481.0
YHH2_k127_8547253_16 cobalamin synthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 474.0
YHH2_k127_8547253_17 Citrate synthase, C-terminal domain K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 467.0
YHH2_k127_8547253_18 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 466.0
YHH2_k127_8547253_19 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 452.0
YHH2_k127_8547253_2 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1046.0
YHH2_k127_8547253_20 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 448.0
YHH2_k127_8547253_21 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 486.0
YHH2_k127_8547253_22 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 451.0
YHH2_k127_8547253_23 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 434.0
YHH2_k127_8547253_24 COGs COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 419.0
YHH2_k127_8547253_25 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 392.0
YHH2_k127_8547253_26 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 401.0
YHH2_k127_8547253_27 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 354.0
YHH2_k127_8547253_28 HpcH/HpaI aldolase/citrate lyase family K01644,K18292 - 4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 338.0
YHH2_k127_8547253_29 HNH endonuclease K07454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 319.0
YHH2_k127_8547253_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 9.81e-304 941.0
YHH2_k127_8547253_30 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 315.0
YHH2_k127_8547253_31 PFAM Pentapeptide repeats (8 copies) K15352 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 306.0
YHH2_k127_8547253_32 methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 305.0
YHH2_k127_8547253_33 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001031 271.0
YHH2_k127_8547253_34 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000006038 267.0
YHH2_k127_8547253_35 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000201 256.0
YHH2_k127_8547253_36 Restriction endonuclease BglII - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008956 241.0
YHH2_k127_8547253_37 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000001163 220.0
YHH2_k127_8547253_38 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000008964 211.0
YHH2_k127_8547253_39 methyltransferase - - - 0.0000000000000000000000000000000000000000000000004057 180.0
YHH2_k127_8547253_4 accessory protein K06959 - - 1.96e-294 922.0
YHH2_k127_8547253_40 toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000426 177.0
YHH2_k127_8547253_41 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family - - - 0.0000000000000000000000000000000000000000000006356 176.0
YHH2_k127_8547253_43 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) K01183,K13695,K19303 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0006022,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009254,GO:0016787,GO:0019538,GO:0030203,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901135,GO:1901564 3.2.1.14 0.000000000000000000000000000000000000004836 156.0
YHH2_k127_8547253_44 - - - - 0.0000000000000000000000000000000000005639 148.0
YHH2_k127_8547253_45 HNH endonuclease K07454 - - 0.00000000000000000000000000000000007529 144.0
YHH2_k127_8547253_46 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000000000000000000000001543 136.0
YHH2_k127_8547253_47 phenylacetate-CoA ligase activity - - - 0.000000000000000000000000000004503 130.0
YHH2_k127_8547253_48 BRO family, N-terminal domain K07741 - - 0.00000000000000000000000003186 119.0
YHH2_k127_8547253_49 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000002689 103.0
YHH2_k127_8547253_5 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.57e-293 903.0
YHH2_k127_8547253_50 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001475 94.0
YHH2_k127_8547253_51 Antitoxin component of a type II toxin-antitoxin (TA) system. Upon K19687 GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0000000000181 67.0
YHH2_k127_8547253_52 Phosphoadenosine phosphosulfate reductase family - - - 0.00000003625 54.0
YHH2_k127_8547253_53 - - - - 0.00001084 58.0
YHH2_k127_8547253_55 TPR repeat - - - 0.0007475 51.0
YHH2_k127_8547253_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 2.489e-238 752.0
YHH2_k127_8547253_7 Acyltransferase - - - 2.949e-235 744.0
YHH2_k127_8547253_8 Patatin-like phospholipase K07001 - - 2.728e-233 743.0
YHH2_k127_8547253_9 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 9.835e-198 625.0
YHH2_k127_8547994_0 PhoQ Sensor K01768,K16923,K19694 - 4.6.1.1 1.54e-298 971.0
YHH2_k127_8547994_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 597.0
YHH2_k127_8547994_2 LmbE family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 490.0
YHH2_k127_8547994_3 chemotaxis protein K03406,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 421.0
YHH2_k127_8547994_4 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 367.0
YHH2_k127_8547994_5 PFAM secretion protein HlyD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 340.0
YHH2_k127_8547994_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 331.0
YHH2_k127_8547994_7 Protein of unknown function (DUF2939) - - - 0.00000000000000000000000000000006543 131.0
YHH2_k127_8547994_8 Belongs to the UPF0434 family K09791 - - 0.000000000000000000001536 96.0
YHH2_k127_8625870_0 RQC K03654 - 3.6.4.12 1.112e-226 716.0
YHH2_k127_8625870_1 Histidine kinase - - - 1.66e-217 696.0
YHH2_k127_8625870_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000005841 188.0
YHH2_k127_8625870_11 N-4 methylation of cytosine K00571 - 2.1.1.72 0.0000000000000001403 92.0
YHH2_k127_8625870_12 DNA (cytosine-5-)-methyltransferase activity - - - 0.0000000000003484 81.0
YHH2_k127_8625870_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.49e-200 628.0
YHH2_k127_8625870_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 314.0
YHH2_k127_8625870_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 308.0
YHH2_k127_8625870_6 Domain of unknown function DUF87 K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001904 267.0
YHH2_k127_8625870_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004878 264.0
YHH2_k127_8625870_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004653 250.0
YHH2_k127_8625870_9 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000002687 237.0
YHH2_k127_8626408_0 COG0618 Exopolyphosphatase-related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 482.0
YHH2_k127_8626408_1 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004389 254.0
YHH2_k127_8626408_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005058 250.0
YHH2_k127_8626408_3 Domain of unknown function (DUF368) K08974 - - 0.00000000000000000000000000000000000000000000000000000000000000000001482 244.0
YHH2_k127_8626408_4 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000007953 235.0
YHH2_k127_8626408_5 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000062 176.0
YHH2_k127_870871_0 FAD linked oxidases, C-terminal domain K06911 - - 0.0 1089.0
YHH2_k127_870871_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 5.086e-225 705.0
YHH2_k127_870871_10 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 309.0
YHH2_k127_870871_11 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 327.0
YHH2_k127_870871_12 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005441 272.0
YHH2_k127_870871_13 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000138 198.0
YHH2_k127_870871_14 PIN domain K18828 - - 0.0000000000000000000000000000000000001628 145.0
YHH2_k127_870871_15 Transposase, IS605 OrfB family K07496 - - 0.00000000000000002709 86.0
YHH2_k127_870871_16 PFAM SMP-30 Gluconolaconase - - - 0.0000000000001693 84.0
YHH2_k127_870871_17 cellulase activity K20276 - - 0.00000000001083 78.0
YHH2_k127_870871_18 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000003315 59.0
YHH2_k127_870871_19 pathogenesis - - - 0.0009201 45.0
YHH2_k127_870871_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 587.0
YHH2_k127_870871_3 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 590.0
YHH2_k127_870871_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 556.0
YHH2_k127_870871_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 499.0
YHH2_k127_870871_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 463.0
YHH2_k127_870871_7 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 443.0
YHH2_k127_870871_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 415.0
YHH2_k127_870871_9 major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 412.0
YHH2_k127_8735478_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1020.0
YHH2_k127_8735478_1 Belongs to the aldehyde dehydrogenase family K00138 - - 2.529e-289 892.0
YHH2_k127_8735478_10 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 383.0
YHH2_k127_8735478_11 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 377.0
YHH2_k127_8735478_12 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 360.0
YHH2_k127_8735478_13 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 355.0
YHH2_k127_8735478_14 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 342.0
YHH2_k127_8735478_15 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
YHH2_k127_8735478_16 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008686 272.0
YHH2_k127_8735478_17 excinuclease ABC activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003537 274.0
YHH2_k127_8735478_18 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000001833 258.0
YHH2_k127_8735478_19 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000009452 245.0
YHH2_k127_8735478_2 TonB-dependent Receptor Plug K02014 - - 5.294e-213 682.0
YHH2_k127_8735478_20 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000009512 208.0
YHH2_k127_8735478_21 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000003179 192.0
YHH2_k127_8735478_22 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000001512 176.0
YHH2_k127_8735478_23 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000001926 159.0
YHH2_k127_8735478_24 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000000000006976 134.0
YHH2_k127_8735478_25 addiction module antidote protein HigA K21498 - - 0.0000000000000000000000000000000005465 132.0
YHH2_k127_8735478_26 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000004703 129.0
YHH2_k127_8735478_27 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000004237 132.0
YHH2_k127_8735478_28 PIN domain - - - 0.000000000000000000000000000000304 126.0
YHH2_k127_8735478_29 acr, cog1565 - - - 0.0000000000000000002349 102.0
YHH2_k127_8735478_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 513.0
YHH2_k127_8735478_30 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000005764 85.0
YHH2_k127_8735478_31 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000005062 71.0
YHH2_k127_8735478_4 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 460.0
YHH2_k127_8735478_5 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 443.0
YHH2_k127_8735478_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 433.0
YHH2_k127_8735478_7 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 428.0
YHH2_k127_8735478_8 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 413.0
YHH2_k127_8735478_9 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 410.0
YHH2_k127_8948688_0 Legume lectin domain - - - 0.0000000000000000000000000000000000004084 157.0
YHH2_k127_8948688_1 PFAM ORF6N domain - - - 0.0000000000000000001761 96.0
YHH2_k127_8948688_2 guanyl-nucleotide exchange factor activity K01387,K07114,K12287 - 3.4.24.3 0.00000000000008889 83.0
YHH2_k127_8948688_3 repressor - - - 0.000000000001245 73.0
YHH2_k127_8948688_4 domain protein - - - 0.00000155 61.0
YHH2_k127_8985469_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1674.0
YHH2_k127_8985469_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0 1262.0
YHH2_k127_8985469_10 Leucine Rich repeat K13730 - - 1.678e-198 657.0
YHH2_k127_8985469_11 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 569.0
YHH2_k127_8985469_12 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 535.0
YHH2_k127_8985469_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 547.0
YHH2_k127_8985469_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 454.0
YHH2_k127_8985469_15 PFAM FIST C domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 453.0
YHH2_k127_8985469_16 ATP-citrate synthase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 422.0
YHH2_k127_8985469_17 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 395.0
YHH2_k127_8985469_18 PFAM SPFH domain Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 364.0
YHH2_k127_8985469_19 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 383.0
YHH2_k127_8985469_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.671e-317 984.0
YHH2_k127_8985469_20 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 357.0
YHH2_k127_8985469_21 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
YHH2_k127_8985469_22 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 334.0
YHH2_k127_8985469_23 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 316.0
YHH2_k127_8985469_24 UDP-N-acetylglucosamine 2-epimerase activity K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 309.0
YHH2_k127_8985469_25 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001605 265.0
YHH2_k127_8985469_26 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000005633 258.0
YHH2_k127_8985469_27 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000001166 236.0
YHH2_k127_8985469_28 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000003347 214.0
YHH2_k127_8985469_29 General secretion pathway protein J K02459 - - 0.000000000000000000000000000000000000000000000004689 179.0
YHH2_k127_8985469_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 6.26e-256 801.0
YHH2_k127_8985469_30 Tellurite resistance K05793 - - 0.00000000000000000000000000000000000000000000002974 174.0
YHH2_k127_8985469_31 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000001016 171.0
YHH2_k127_8985469_32 Tellurite resistance K05793 - - 0.00000000000000000000000000000000000000000001212 174.0
YHH2_k127_8985469_33 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000000000000959 162.0
YHH2_k127_8985469_34 GTP binding - - - 0.0000000000000000000000000000000009234 140.0
YHH2_k127_8985469_35 CHAP domain containing protein - - - 0.00000000000000000000000000000000349 136.0
YHH2_k127_8985469_36 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000002935 128.0
YHH2_k127_8985469_37 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000392 126.0
YHH2_k127_8985469_38 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000006647 125.0
YHH2_k127_8985469_39 Planctomycete cytochrome C - - - 0.000000000000000000000000000001079 126.0
YHH2_k127_8985469_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.787e-243 760.0
YHH2_k127_8985469_40 CDGSH-type zinc finger. Function unknown. - - - 0.0000000000000000000000000007769 114.0
YHH2_k127_8985469_41 TIR domain - - - 0.00000000000000000000003477 117.0
YHH2_k127_8985469_42 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000007741 101.0
YHH2_k127_8985469_43 PFAM Mo-dependent nitrogenase K05793,K05795 - - 0.00000000000000000001187 103.0
YHH2_k127_8985469_44 NusG domain II - - - 0.00000000000000002816 86.0
YHH2_k127_8985469_46 capsule polysaccharide biosynthetic process - - - 0.00000000000009447 85.0
YHH2_k127_8985469_48 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.00000006157 55.0
YHH2_k127_8985469_49 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000001403 63.0
YHH2_k127_8985469_5 synthase subunit 1 K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 1.435e-242 764.0
YHH2_k127_8985469_50 lipoprotein - - - 0.0002229 48.0
YHH2_k127_8985469_6 Belongs to the GPI family K01810 - 5.3.1.9 1.572e-239 751.0
YHH2_k127_8985469_7 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 2.769e-213 672.0
YHH2_k127_8985469_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.24e-210 663.0
YHH2_k127_8985469_9 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.618e-199 631.0
YHH2_k127_9045176_0 CHAT domain - - - 1.221e-199 646.0
YHH2_k127_9045176_1 ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 613.0
YHH2_k127_9045176_2 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000001457 165.0
YHH2_k127_9045176_3 guanyl-nucleotide exchange factor activity K01387,K07114,K12287 - 3.4.24.3 0.000000000000000000000001572 122.0
YHH2_k127_9045176_4 C-terminal domain of CHU protein family - - - 0.000000009177 70.0
YHH2_k127_936138_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1733.0
YHH2_k127_936138_1 family UPF0027 K14415 - 6.5.1.3 8.628e-239 761.0
YHH2_k127_936138_10 Copper resistance protein D - - - 0.000000000000000000000000000000000000000002819 159.0
YHH2_k127_936138_11 PFAM Rhodanese-like domain - - - 0.000000000000000000000000000000000000005267 147.0
YHH2_k127_936138_12 Protein of unknown function (DUF2809) - - - 0.000000000000000000000000000000000007574 140.0
YHH2_k127_936138_13 Sterol carrier protein - - - 0.0000000001189 67.0
YHH2_k127_936138_2 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 7.866e-198 632.0
YHH2_k127_936138_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 580.0
YHH2_k127_936138_4 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 460.0
YHH2_k127_936138_5 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 328.0
YHH2_k127_936138_6 Transposase, IS605 OrfB family K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002788 284.0
YHH2_k127_936138_7 O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008838 269.0
YHH2_k127_936138_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006383 264.0
YHH2_k127_936138_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000863 262.0
YHH2_k127_9394419_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0 1348.0
YHH2_k127_9394419_1 Belongs to the ClpA ClpB family K03694 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043335,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 - 0.0 1066.0
YHH2_k127_9394419_10 Belongs to the glycosyl hydrolase 57 family - - - 6.261e-220 695.0
YHH2_k127_9394419_11 Mo-co oxidoreductase dimerisation domain - - - 1.893e-210 661.0
YHH2_k127_9394419_12 PUA-like domain K00958 - 2.7.7.4 1.113e-206 647.0
YHH2_k127_9394419_13 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.152e-205 652.0
YHH2_k127_9394419_14 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 9.032e-204 641.0
YHH2_k127_9394419_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 655.0
YHH2_k127_9394419_16 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 604.0
YHH2_k127_9394419_17 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 580.0
YHH2_k127_9394419_18 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 591.0
YHH2_k127_9394419_19 Belongs to the GARS family K01945,K13713 GO:0000166,GO:0003674,GO:0003824,GO:0004637,GO:0005488,GO:0005524,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 550.0
YHH2_k127_9394419_2 N-6 DNA Methylase - - - 1.16e-321 1013.0
YHH2_k127_9394419_20 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 538.0
YHH2_k127_9394419_21 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 526.0
YHH2_k127_9394419_22 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 533.0
YHH2_k127_9394419_23 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 521.0
YHH2_k127_9394419_24 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 501.0
YHH2_k127_9394419_25 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 503.0
YHH2_k127_9394419_26 PFAM Transposase, IS605 OrfB, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 476.0
YHH2_k127_9394419_27 Pfam Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 442.0
YHH2_k127_9394419_28 WD-40 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 462.0
YHH2_k127_9394419_29 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 406.0
YHH2_k127_9394419_3 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 9.275e-282 881.0
YHH2_k127_9394419_30 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 414.0
YHH2_k127_9394419_31 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 395.0
YHH2_k127_9394419_32 ABC transporter permease K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 360.0
YHH2_k127_9394419_33 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 366.0
YHH2_k127_9394419_34 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 353.0
YHH2_k127_9394419_35 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 329.0
YHH2_k127_9394419_36 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 323.0
YHH2_k127_9394419_37 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 325.0
YHH2_k127_9394419_38 Glycosyl transferase K12984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 295.0
YHH2_k127_9394419_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 295.0
YHH2_k127_9394419_4 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.753e-274 861.0
YHH2_k127_9394419_40 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000001671 248.0
YHH2_k127_9394419_41 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000001777 238.0
YHH2_k127_9394419_42 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000002655 235.0
YHH2_k127_9394419_43 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000002858 232.0
YHH2_k127_9394419_44 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000000000000001763 226.0
YHH2_k127_9394419_45 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000001432 208.0
YHH2_k127_9394419_46 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000002466 204.0
YHH2_k127_9394419_47 Phosphoribosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000005213 209.0
YHH2_k127_9394419_48 Uncharacterized conserved protein (DUF2183) - - - 0.0000000000000000000000000000000000000000000000000000631 200.0
YHH2_k127_9394419_49 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000004328 186.0
YHH2_k127_9394419_5 FtsX-like permease family K02004 - - 2.034e-269 852.0
YHH2_k127_9394419_50 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000005849 192.0
YHH2_k127_9394419_51 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000003471 193.0
YHH2_k127_9394419_52 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000472 183.0
YHH2_k127_9394419_53 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000006262 164.0
YHH2_k127_9394419_54 membrane-bound metal-dependent hydrolase - - - 0.00000000000000000000000000000000000000000002735 169.0
YHH2_k127_9394419_55 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000287 164.0
YHH2_k127_9394419_56 PFAM YCII-related K09780 - - 0.000000000000000000000000000000000000000001395 157.0
YHH2_k127_9394419_57 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000904 160.0
YHH2_k127_9394419_58 - - - - 0.0000000000000000000000000000000000001737 156.0
YHH2_k127_9394419_59 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000002696 142.0
YHH2_k127_9394419_6 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.86e-251 782.0
YHH2_k127_9394419_60 RDD family - - - 0.00000000000000000000000000000001153 131.0
YHH2_k127_9394419_61 domain protein - - - 0.00000000000000000000000000000003086 137.0
YHH2_k127_9394419_62 RNA-binding protein - - - 0.00000000000000000000000000000003561 126.0
YHH2_k127_9394419_63 nuclease activity - - - 0.0000000000000000000000000000003211 126.0
YHH2_k127_9394419_64 - - - - 0.000000000000000000000000000001841 139.0
YHH2_k127_9394419_66 Antirepressor - - - 0.00000000000000000000000000125 119.0
YHH2_k127_9394419_67 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000005289 111.0
YHH2_k127_9394419_68 cytochrome - - - 0.0000000000000000000000003069 110.0
YHH2_k127_9394419_69 - - - - 0.000000000000000000000001542 107.0
YHH2_k127_9394419_7 Diguanylate cyclase K13924 - 2.1.1.80,3.1.1.61 8.459e-250 789.0
YHH2_k127_9394419_70 - - - - 0.000000000000000009133 89.0
YHH2_k127_9394419_71 is891 is1136 is1341 K07496 - - 0.000000000000000009525 85.0
YHH2_k127_9394419_72 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000004441 83.0
YHH2_k127_9394419_74 NYN domain - - - 0.0000000000009922 68.0
YHH2_k127_9394419_75 - - - - 0.00000000002037 66.0
YHH2_k127_9394419_76 PFAM porin, Gram-negative type - - - 0.000000000396 72.0
YHH2_k127_9394419_77 Putative restriction endonuclease - - - 0.00000003088 57.0
YHH2_k127_9394419_8 ABC transporter transmembrane region K06148 - - 2.863e-228 721.0
YHH2_k127_9394419_9 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 2.17e-220 702.0
YHH2_k127_9395242_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1306.0
YHH2_k127_9395242_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 4.743e-288 901.0
YHH2_k127_9395242_10 MazG-like family - - - 0.0000000000000000000000000000000000000003864 151.0
YHH2_k127_9395242_11 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000004645 128.0
YHH2_k127_9395242_12 PFAM Ferrous iron transporter, FeoA subunit K04758 - - 0.0000000000000000000000000002665 115.0
YHH2_k127_9395242_13 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000006184 119.0
YHH2_k127_9395242_14 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000003693 111.0
YHH2_k127_9395242_15 - - - - 0.0000000000000000000004512 98.0
YHH2_k127_9395242_16 pilus assembly protein, PilZ - - - 0.00000000000000000001116 96.0
YHH2_k127_9395242_17 PFAM FeoA K04758 - - 0.0000000000001281 74.0
YHH2_k127_9395242_18 PFAM VanZ - - - 0.00000001499 61.0
YHH2_k127_9395242_19 Lysozyme inhibitor LprI - - - 0.000001913 57.0
YHH2_k127_9395242_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 578.0
YHH2_k127_9395242_3 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 505.0
YHH2_k127_9395242_4 COG0714 MoxR-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 458.0
YHH2_k127_9395242_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 387.0
YHH2_k127_9395242_6 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 366.0
YHH2_k127_9395242_7 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517,K12974 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 291.0
YHH2_k127_9395242_8 pilus assembly protein, PilZ - - - 0.00000000000000000000000000000000000000000001458 165.0
YHH2_k127_9395242_9 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000001383 166.0
YHH2_k127_9410877_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1081.0
YHH2_k127_9410877_1 Multicopper oxidase - - - 3.789e-257 802.0
YHH2_k127_9410877_10 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000000000000000000000000000000000002034 185.0
YHH2_k127_9410877_11 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000000000000000101 177.0
YHH2_k127_9410877_12 regulation of response to stimulus - - - 0.0000000000000000000000000000000000000000004154 183.0
YHH2_k127_9410877_13 endopeptidase activity - - - 0.000000000000000000000000000000000000000002183 181.0
YHH2_k127_9410877_14 cellulose binding - - - 0.0000000000000000000000000000000007684 153.0
YHH2_k127_9410877_15 General Secretion Pathway protein K02457 - - 0.00000000000000000000000000000000123 135.0
YHH2_k127_9410877_17 DNA polymerase - - - 0.0000000000000000000000000000001655 128.0
YHH2_k127_9410877_18 Belongs to the UPF0235 family K09131 - - 0.000000000000000000004329 96.0
YHH2_k127_9410877_19 recombinase activity - - - 0.00000000000000003234 83.0
YHH2_k127_9410877_2 Glycosyl Transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 599.0
YHH2_k127_9410877_20 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000003771 94.0
YHH2_k127_9410877_21 PFAM Resolvase, N terminal domain - - - 0.00000000001161 66.0
YHH2_k127_9410877_22 recombinase activity - - - 0.000000001509 59.0
YHH2_k127_9410877_23 amine dehydrogenase activity - - - 0.0007284 46.0
YHH2_k127_9410877_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 563.0
YHH2_k127_9410877_4 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 538.0
YHH2_k127_9410877_5 TIGRFAM Outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 567.0
YHH2_k127_9410877_6 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 353.0
YHH2_k127_9410877_7 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 306.0
YHH2_k127_9410877_8 PFAM Copper resistance protein B precursor (CopB) K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000382 274.0
YHH2_k127_9417342_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07646 - 2.7.13.3 4.245e-271 849.0
YHH2_k127_9417342_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 7.719e-259 805.0
YHH2_k127_9417342_10 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 346.0
YHH2_k127_9417342_11 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 339.0
YHH2_k127_9417342_12 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 321.0
YHH2_k127_9417342_13 PFAM NADH ubiquinone K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 305.0
YHH2_k127_9417342_14 Histidine kinase K17292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 316.0
YHH2_k127_9417342_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 308.0
YHH2_k127_9417342_16 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000001163 224.0
YHH2_k127_9417342_17 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000459 153.0
YHH2_k127_9417342_18 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000004954 117.0
YHH2_k127_9417342_2 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 - 1.12.1.2 1.689e-213 678.0
YHH2_k127_9417342_20 Histidine kinase K17292 - - 0.000000000000000000001808 94.0
YHH2_k127_9417342_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 610.0
YHH2_k127_9417342_4 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 585.0
YHH2_k127_9417342_5 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 537.0
YHH2_k127_9417342_6 Permease YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 387.0
YHH2_k127_9417342_7 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 368.0
YHH2_k127_9417342_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 375.0
YHH2_k127_9417342_9 Permease YjgP YjgQ K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
YHH2_k127_9486114_0 elongation factor G K02355 - - 2.814e-257 810.0
YHH2_k127_9486114_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 2.204e-197 620.0
YHH2_k127_9486114_10 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000001082 190.0
YHH2_k127_9486114_11 PFAM Plasmid maintenance system killer protein - - - 0.0000000000000000000005942 98.0
YHH2_k127_9486114_12 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000008817 84.0
YHH2_k127_9486114_13 B-1 B cell differentiation K07126,K18197 - 4.2.2.23 0.000000000000007445 88.0
YHH2_k127_9486114_14 - - - - 0.000007298 50.0
YHH2_k127_9486114_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 591.0
YHH2_k127_9486114_3 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 578.0
YHH2_k127_9486114_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 548.0
YHH2_k127_9486114_5 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 440.0
YHH2_k127_9486114_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 427.0
YHH2_k127_9486114_7 deoxyhypusine monooxygenase activity K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 334.0
YHH2_k127_9486114_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 295.0
YHH2_k127_9486114_9 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 298.0
YHH2_k127_9657383_0 - - - - 0.0000000000000000000000000000000000000001726 164.0
YHH2_k127_9657383_1 Phosphoadenosine phosphosulfate reductase family - - - 0.0000000000000000000000000000000003149 143.0
YHH2_k127_9657383_2 Protein of unknown function (DUF2493) - - - 0.00000000000000000001411 96.0
YHH2_k127_9657383_3 Helix-turn-helix XRE-family like proteins K07726 - - 0.000004037 52.0
YHH2_k127_9657383_4 Helix-turn-helix domain - - - 0.0002689 46.0
YHH2_k127_9696769_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1277.0
YHH2_k127_9696769_1 AAA domain - - - 0.0 1139.0
YHH2_k127_9696769_10 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 538.0
YHH2_k127_9696769_11 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 526.0
YHH2_k127_9696769_12 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 481.0
YHH2_k127_9696769_13 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 471.0
YHH2_k127_9696769_14 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 440.0
YHH2_k127_9696769_15 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 421.0
YHH2_k127_9696769_16 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 404.0
YHH2_k127_9696769_17 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 402.0
YHH2_k127_9696769_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 388.0
YHH2_k127_9696769_19 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 351.0
YHH2_k127_9696769_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.847e-270 838.0
YHH2_k127_9696769_20 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 339.0
YHH2_k127_9696769_21 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 311.0
YHH2_k127_9696769_22 Hydrolase K20862 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0022611,GO:0032502,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000000000000000000000000000000000002149 249.0
YHH2_k127_9696769_23 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000872 246.0
YHH2_k127_9696769_24 COG2199 FOG GGDEF domain K18968 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000001166 237.0
YHH2_k127_9696769_25 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000000002683 231.0
YHH2_k127_9696769_26 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000003897 229.0
YHH2_k127_9696769_27 regulation of response to stimulus - - - 0.000000000000000000000000000000000000000000000000000000000000002014 230.0
YHH2_k127_9696769_28 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000008027 199.0
YHH2_k127_9696769_29 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000000008325 171.0
YHH2_k127_9696769_3 arginine decarboxylase K01585 - 4.1.1.19 1.082e-268 841.0
YHH2_k127_9696769_30 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000002306 151.0
YHH2_k127_9696769_31 PFAM Stage II sporulation E family protein K07315 - 3.1.3.3 0.00000000000000000000000000000001771 134.0
YHH2_k127_9696769_32 PFAM Biopolymer transport protein ExbD TolR - - - 0.00000000000000000000000000162 116.0
YHH2_k127_9696769_33 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000001012 113.0
YHH2_k127_9696769_34 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000007772 71.0
YHH2_k127_9696769_36 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000002824 57.0
YHH2_k127_9696769_37 - - - - 0.000003172 49.0
YHH2_k127_9696769_38 - - - - 0.00006318 45.0
YHH2_k127_9696769_39 Histidine kinase - - - 0.0002024 51.0
YHH2_k127_9696769_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.012e-240 751.0
YHH2_k127_9696769_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.385e-230 718.0
YHH2_k127_9696769_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 3.957e-228 719.0
YHH2_k127_9696769_7 PFAM response regulator receiver - - - 4.806e-228 713.0
YHH2_k127_9696769_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.22e-199 632.0
YHH2_k127_9696769_9 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 2.231e-194 613.0
YHH2_k127_9711512_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 547.0
YHH2_k127_9711512_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0015711,GO:0015740,GO:0015849,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0071702 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 472.0
YHH2_k127_9711512_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
YHH2_k127_9711512_3 TRAP-type C4-dicarboxylate transport system small permease component K11689 - - 0.000000000000000000000000000000000000000000000000641 179.0
YHH2_k127_9711512_4 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000412 135.0
YHH2_k127_9753346_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1077.0
YHH2_k127_9753346_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 504.0
YHH2_k127_9753346_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 444.0
YHH2_k127_9753346_3 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 391.0
YHH2_k127_9753346_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000002336 228.0
YHH2_k127_9753346_5 - - - - 0.00000000000000000000000000000000000000000000000000000000004397 212.0
YHH2_k127_9753346_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000008989 181.0
YHH2_k127_9753346_7 Oxygen tolerance - - - 0.00000000000000000000000000007148 132.0
YHH2_k127_9753346_8 HNH nucleases - - - 0.00000000000005512 79.0
YHH2_k127_9832370_0 SAF domain K01654 - 2.5.1.56 0.0 1066.0
YHH2_k127_9832370_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 6.76e-223 706.0
YHH2_k127_9832370_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 359.0
YHH2_k127_9832370_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 334.0
YHH2_k127_9832370_12 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 287.0
YHH2_k127_9832370_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
YHH2_k127_9832370_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001502 254.0
YHH2_k127_9832370_15 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002312 255.0
YHH2_k127_9832370_16 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004423 247.0
YHH2_k127_9832370_17 Cytidylyltransferase K18431 - 2.7.7.82 0.00000000000000000000000000000000000000000000000001666 187.0
YHH2_k127_9832370_18 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000004616 135.0
YHH2_k127_9832370_19 - - - - 0.000000000000000000000000000000008191 131.0
YHH2_k127_9832370_2 B12 binding domain - - - 7.722e-208 654.0
YHH2_k127_9832370_20 - - - - 0.0000000000000000004961 87.0
YHH2_k127_9832370_21 Peptidase, M23 K21471 - - 0.00000000000001383 85.0
YHH2_k127_9832370_22 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000001017 57.0
YHH2_k127_9832370_23 - - - - 0.00007675 52.0
YHH2_k127_9832370_3 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 3.663e-199 627.0
YHH2_k127_9832370_4 PFAM Glycosyl transferase, family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 476.0
YHH2_k127_9832370_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 475.0
YHH2_k127_9832370_6 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 464.0
YHH2_k127_9832370_7 Glycosyl transferase, family 2 K13500 - 2.4.1.175,2.4.1.226 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 484.0
YHH2_k127_9832370_8 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 409.0
YHH2_k127_9832370_9 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 407.0
YHH2_k127_9838800_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2198.0
YHH2_k127_9838800_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1987.0
YHH2_k127_9838800_10 ABC transporter transmembrane region K12541 - - 4.291e-261 822.0
YHH2_k127_9838800_100 regulation of response to stimulus - - - 0.000000000000000000000000000000000000006165 170.0
YHH2_k127_9838800_101 phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000726 164.0
YHH2_k127_9838800_102 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000054 144.0
YHH2_k127_9838800_103 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000001307 141.0
YHH2_k127_9838800_104 SURF1-like protein K14998 - - 0.00000000000000000000000000000000006676 143.0
YHH2_k127_9838800_105 YGGT family K02221 - - 0.00000000000000000000000000000000009593 140.0
YHH2_k127_9838800_106 - - - - 0.0000000000000000000000000000000001398 140.0
YHH2_k127_9838800_107 Clostripain family - - - 0.0000000000000000000000000000000003347 153.0
YHH2_k127_9838800_108 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000000000000007155 137.0
YHH2_k127_9838800_109 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000007199 129.0
YHH2_k127_9838800_11 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.339e-245 767.0
YHH2_k127_9838800_110 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000000000000000000000000004047 128.0
YHH2_k127_9838800_111 - - - - 0.000000000000000000000000000000143 124.0
YHH2_k127_9838800_113 signal sequence binding - - - 0.00000000000000000000000000001943 124.0
YHH2_k127_9838800_115 mRNA binding K07339 - - 0.00000000000000000000001147 100.0
YHH2_k127_9838800_116 Ribosomal protein L30 K02907 - - 0.000000000000000000001808 94.0
YHH2_k127_9838800_117 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000001261 89.0
YHH2_k127_9838800_118 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000004234 82.0
YHH2_k127_9838800_119 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000002255 94.0
YHH2_k127_9838800_12 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.468e-240 746.0
YHH2_k127_9838800_120 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000001245 70.0
YHH2_k127_9838800_121 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000425 77.0
YHH2_k127_9838800_122 Two component regulator propeller - - - 0.000000002062 71.0
YHH2_k127_9838800_124 heat shock protein binding K03686,K14002 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006986,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0019538,GO:0019941,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031974,GO:0033554,GO:0034620,GO:0034975,GO:0034976,GO:0035966,GO:0035967,GO:0036503,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051087,GO:0051603,GO:0051716,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901698 - 0.000004097 58.0
YHH2_k127_9838800_13 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.549e-237 742.0
YHH2_k127_9838800_14 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 1.592e-232 730.0
YHH2_k127_9838800_15 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.537e-232 721.0
YHH2_k127_9838800_16 PFAM Transglycosylase SLT domain K08309 - - 1.593e-201 646.0
YHH2_k127_9838800_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 5.606e-197 634.0
YHH2_k127_9838800_18 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 591.0
YHH2_k127_9838800_19 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 560.0
YHH2_k127_9838800_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1523.0
YHH2_k127_9838800_20 TIGRFAM general secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 522.0
YHH2_k127_9838800_21 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 532.0
YHH2_k127_9838800_22 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 499.0
YHH2_k127_9838800_23 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 514.0
YHH2_k127_9838800_24 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 528.0
YHH2_k127_9838800_25 Outer membrane protein, OmpA MotB, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 520.0
YHH2_k127_9838800_26 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 489.0
YHH2_k127_9838800_27 Alternative locus ID K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 502.0
YHH2_k127_9838800_28 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 500.0
YHH2_k127_9838800_29 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008781 480.0
YHH2_k127_9838800_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1171.0
YHH2_k127_9838800_30 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 467.0
YHH2_k127_9838800_31 Thymidylate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 464.0
YHH2_k127_9838800_32 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 455.0
YHH2_k127_9838800_33 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 446.0
YHH2_k127_9838800_34 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007715 443.0
YHH2_k127_9838800_35 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 438.0
YHH2_k127_9838800_36 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 424.0
YHH2_k127_9838800_37 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 412.0
YHH2_k127_9838800_38 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 387.0
YHH2_k127_9838800_39 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 363.0
YHH2_k127_9838800_4 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1138.0
YHH2_k127_9838800_40 PFAM Radical SAM K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 366.0
YHH2_k127_9838800_41 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
YHH2_k127_9838800_42 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 368.0
YHH2_k127_9838800_43 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 364.0
YHH2_k127_9838800_44 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 339.0
YHH2_k127_9838800_45 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 343.0
YHH2_k127_9838800_46 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 335.0
YHH2_k127_9838800_47 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008226 331.0
YHH2_k127_9838800_48 alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 313.0
YHH2_k127_9838800_49 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 322.0
YHH2_k127_9838800_5 glycosyl transferase, family 2 K20444 - - 0.0 1095.0
YHH2_k127_9838800_50 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 323.0
YHH2_k127_9838800_51 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 301.0
YHH2_k127_9838800_52 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 299.0
YHH2_k127_9838800_53 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 300.0
YHH2_k127_9838800_54 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 293.0
YHH2_k127_9838800_55 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 292.0
YHH2_k127_9838800_56 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 293.0
YHH2_k127_9838800_57 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001901 273.0
YHH2_k127_9838800_58 Zinc metalloprotease (Elastase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003505 306.0
YHH2_k127_9838800_59 KilA-N - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005488 278.0
YHH2_k127_9838800_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.0 1051.0
YHH2_k127_9838800_60 6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000002273 267.0
YHH2_k127_9838800_61 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006462 263.0
YHH2_k127_9838800_62 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001009 255.0
YHH2_k127_9838800_63 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000005397 250.0
YHH2_k127_9838800_64 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009058 246.0
YHH2_k127_9838800_65 TIGRFAM RHS repeat-associated core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001929 278.0
YHH2_k127_9838800_66 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000002879 238.0
YHH2_k127_9838800_67 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000004511 235.0
YHH2_k127_9838800_68 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000004579 236.0
YHH2_k127_9838800_69 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000001589 237.0
YHH2_k127_9838800_7 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 6.696e-309 955.0
YHH2_k127_9838800_70 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000006816 232.0
YHH2_k127_9838800_71 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000003909 235.0
YHH2_k127_9838800_72 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004274 248.0
YHH2_k127_9838800_73 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000000006488 228.0
YHH2_k127_9838800_74 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000003636 226.0
YHH2_k127_9838800_75 - - - - 0.000000000000000000000000000000000000000000000000000000000000001965 226.0
YHH2_k127_9838800_76 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000002143 221.0
YHH2_k127_9838800_77 COG1100 GTPase SAR1 and related small G - - - 0.0000000000000000000000000000000000000000000000000000000000003091 216.0
YHH2_k127_9838800_78 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000005704 208.0
YHH2_k127_9838800_79 Sterol carrier protein - - - 0.000000000000000000000000000000000000000000000000000000001813 203.0
YHH2_k127_9838800_8 Transposase - - - 2.161e-308 952.0
YHH2_k127_9838800_80 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000001168 207.0
YHH2_k127_9838800_81 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000001227 199.0
YHH2_k127_9838800_82 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000007527 196.0
YHH2_k127_9838800_83 Ras of Complex, Roc, domain of DAPkinase - - - 0.000000000000000000000000000000000000000000000000000002238 195.0
YHH2_k127_9838800_84 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001472 190.0
YHH2_k127_9838800_85 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000002684 190.0
YHH2_k127_9838800_86 - - - - 0.000000000000000000000000000000000000000000000000000044 194.0
YHH2_k127_9838800_87 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000002973 186.0
YHH2_k127_9838800_88 PFAM Rickettsia 17 kDa surface antigen - - - 0.00000000000000000000000000000000000000000000004114 173.0
YHH2_k127_9838800_89 PFAM Staphylococcal nuclease - - - 0.00000000000000000000000000000000000000000000007747 175.0
YHH2_k127_9838800_9 PFAM binding-protein-dependent transport systems inner membrane component K02037 - - 1.659e-274 863.0
YHH2_k127_9838800_90 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000001063 171.0
YHH2_k127_9838800_91 PFAM Amino acid-binding ACT K03567 - - 0.0000000000000000000000000000000000000000000001129 173.0
YHH2_k127_9838800_92 Domain of unknown function DUF29 - - - 0.0000000000000000000000000000000000000000000001725 173.0
YHH2_k127_9838800_93 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000006109 168.0
YHH2_k127_9838800_94 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000002102 159.0
YHH2_k127_9838800_95 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000006729 160.0
YHH2_k127_9838800_96 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000009233 160.0
YHH2_k127_9838800_97 Ferredoxin - - - 0.00000000000000000000000000000000000000001926 154.0
YHH2_k127_9838800_98 Di-glucose binding within endoplasmic reticulum - - - 0.00000000000000000000000000000000000000156 172.0
YHH2_k127_9838800_99 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000000002013 148.0