Overview

ID MAG04542
Name YHH2_bin.52
Sample SMP0122
Taxonomy
Kingdom Archaea
Phylum Nanobdellota
Class Nanobdellia
Order Woesearchaeales
Family JAGWAF01
Genus
Species
Assembly information
Completeness (%) 72.01
Contamination (%) 0.77
GC content (%) 45.0
N50 (bp) 3,540
Genome size (bp) 723,430

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes566

Gene name Description KEGG GOs EC E-value Score Sequence
YHH2_k127_10016805_0 RimK-like ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000001791 179.0
YHH2_k127_10065498_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K22446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 270.0
YHH2_k127_10065498_2 O-methyltransferase - - - 0.000000000003836 74.0
YHH2_k127_10066009_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000002292 122.0
YHH2_k127_1030651_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000003122 169.0
YHH2_k127_1030651_1 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000009375 154.0
YHH2_k127_1030651_2 Transcriptional regulator, XRE family - - - 0.0000000000000000000000000000003397 129.0
YHH2_k127_1030651_3 Fic/DOC family - - - 0.00000000000000000000000000003528 119.0
YHH2_k127_10356225_0 Belongs to the peptidase S16 family K06870 - - 0.00000000000000000000000000000000000000000000000000001981 210.0
YHH2_k127_10356225_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.000008062 55.0
YHH2_k127_10398937_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 5.787e-255 810.0
YHH2_k127_10398937_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 301.0
YHH2_k127_10398937_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000195 185.0
YHH2_k127_10398937_3 transcription termination protein NusA K02600 - - 0.00000000000000000005551 95.0
YHH2_k127_10398937_4 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.00000004569 57.0
YHH2_k127_10439554_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 301.0
YHH2_k127_10439554_1 RNA binding K07581 - - 0.000000000000001322 85.0
YHH2_k127_10558767_0 Methyltransferase small domain - - - 0.000007447 57.0
YHH2_k127_10566110_0 mRNA decay K07562 - - 0.00000000000002618 78.0
YHH2_k127_10566110_1 Protein of unknown function (DUF460) K09150 - - 0.0000382 55.0
YHH2_k127_10577108_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 396.0
YHH2_k127_10577108_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000004472 203.0
YHH2_k127_10601139_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 357.0
YHH2_k127_10601139_1 - - - - 0.0000000000000002957 80.0
YHH2_k127_10636176_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000008776 156.0
YHH2_k127_10636176_1 Fibronectin type III domain - - - 0.0004124 52.0
YHH2_k127_1063747_0 S-adenosylmethionine synthetase K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 520.0
YHH2_k127_1063747_1 MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000547 85.0
YHH2_k127_1063747_2 PFAM Bile acid sodium symporter K03453 - - 0.00000513 57.0
YHH2_k127_10671337_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K22446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000003441 196.0
YHH2_k127_10671337_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000001522 72.0
YHH2_k127_10671337_2 NUDIX domain - - - 0.00000000001063 74.0
YHH2_k127_10671337_3 belongs to the nudix hydrolase family - - - 0.00000000001609 71.0
YHH2_k127_1067879_0 mannose-1-phosphate guanylyltransferase activity K00971,K01840,K16011 - 2.7.7.13,5.3.1.8,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007151 281.0
YHH2_k127_1067879_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000001542 223.0
YHH2_k127_1067879_2 - - - - 0.000000004147 63.0
YHH2_k127_10679337_0 COG0058 Glucan phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 513.0
YHH2_k127_10679337_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000495 255.0
YHH2_k127_10679337_2 Pyrimidine dimer DNA glycosylase K01161 - 3.1.25.1 0.0000000000000000000009754 100.0
YHH2_k127_10679337_3 - - - - 0.0000000000003682 75.0
YHH2_k127_10679337_4 Domain of Unknown Function with PDB structure (DUF3850) - - - 0.0001663 48.0
YHH2_k127_10700492_0 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000001641 150.0
YHH2_k127_10700492_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.0000000000000000000001913 100.0
YHH2_k127_10700492_2 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000008865 76.0
YHH2_k127_10700492_3 Belongs to the PDCD5 family K06875 - - 0.000003141 53.0
YHH2_k127_10769062_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000004915 165.0
YHH2_k127_10769062_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0001843 46.0
YHH2_k127_10811794_0 BRO family, N-terminal domain K14623 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 308.0
YHH2_k127_10811794_1 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000003758 228.0
YHH2_k127_10817703_0 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000008698 107.0
YHH2_k127_10817703_1 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000008725 74.0
YHH2_k127_10931701_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 329.0
YHH2_k127_10931701_1 CYTH K05873 - 4.6.1.1 0.0000000000000000000000000001139 122.0
YHH2_k127_10931701_2 PFAM metallophosphoesterase K07096 - - 0.000000000000000001461 95.0
YHH2_k127_10982418_0 Conserved hypothetical protein 95 K07579 - - 0.000000000000000000000000000000000000000000000002337 181.0
YHH2_k127_10982418_1 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000008835 171.0
YHH2_k127_10982418_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000000002867 76.0
YHH2_k127_11070_0 DHHA1 domain K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003972 264.0
YHH2_k127_11070_1 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000128 175.0
YHH2_k127_11070_2 Mediates influx of magnesium ions K03284 - - 0.000000000000000000005489 104.0
YHH2_k127_11103484_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000007662 154.0
YHH2_k127_11103484_1 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000609 119.0
YHH2_k127_11103484_2 PFAM Radical SAM domain protein K07129 - - 0.0000000000000005439 84.0
YHH2_k127_11415149_0 NOL1 NOP2 sun family - - - 0.00000000000000000000000000000000000000000000000000002161 198.0
YHH2_k127_11415149_1 PUA domain K07565 - - 0.0000001245 60.0
YHH2_k127_1141826_0 Peptidase M50 - - - 0.000000000000000000000000000000000000000001527 164.0
YHH2_k127_1141826_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000006792 91.0
YHH2_k127_1141826_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000009751 69.0
YHH2_k127_1147310_0 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000000000000000002702 123.0
YHH2_k127_11510875_0 Glycogen starch synthase K00693 GO:0000271,GO:0000272,GO:0003674,GO:0003824,GO:0004373,GO:0005488,GO:0005515,GO:0005536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005938,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005980,GO:0005981,GO:0006073,GO:0006091,GO:0006109,GO:0006112,GO:0006914,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008194,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009250,GO:0009251,GO:0009267,GO:0009605,GO:0009743,GO:0009744,GO:0009746,GO:0009749,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0009991,GO:0010033,GO:0010604,GO:0010675,GO:0010676,GO:0010906,GO:0010907,GO:0015629,GO:0015980,GO:0016051,GO:0016052,GO:0016236,GO:0016740,GO:0016757,GO:0016758,GO:0016772,GO:0019222,GO:0030246,GO:0030863,GO:0030864,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031667,GO:0031668,GO:0031669,GO:0032881,GO:0033554,GO:0033692,GO:0034284,GO:0034285,GO:0034637,GO:0034645,GO:0035251,GO:0036094,GO:0042221,GO:0042594,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043265,GO:0043467,GO:0043470,GO:0043471,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044464,GO:0045819,GO:0045913,GO:0046527,GO:0046983,GO:0048029,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0060255,GO:0061547,GO:0061723,GO:0061912,GO:0061919,GO:0062012,GO:0062013,GO:0065007,GO:0070873,GO:0070875,GO:0070887,GO:0071310,GO:0071322,GO:0071324,GO:0071329,GO:0071496,GO:0071704,GO:0071944,GO:0080090,GO:0099568,GO:1901575,GO:1901576,GO:1901700,GO:1901701 2.4.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 439.0
YHH2_k127_11510875_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 409.0
YHH2_k127_11510875_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000003491 132.0
YHH2_k127_11510875_3 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000002646 91.0
YHH2_k127_11510875_4 Cupredoxin-like domain - - - 0.000000000000000007139 90.0
YHH2_k127_11510875_5 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000003366 57.0
YHH2_k127_11647845_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 581.0
YHH2_k127_11792987_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000003588 126.0
YHH2_k127_11792987_1 Methyltransferase domain - - - 0.000000000006261 73.0
YHH2_k127_11792987_2 Presenilin, signal peptide peptidase, family - - - 0.00000003655 62.0
YHH2_k127_11793522_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 360.0
YHH2_k127_11793522_1 CRISPR-associated protein cas4 K07464 - 3.1.12.1 0.000000004842 61.0
YHH2_k127_11793522_2 PFAM PRC-barrel domain - - - 0.0003898 47.0
YHH2_k127_11804632_0 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000001415 188.0
YHH2_k127_11804632_1 binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000002042 137.0
YHH2_k127_11804632_2 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000281 133.0
YHH2_k127_11804632_3 PFAM Ribosomal protein K02912 - - 0.000000000005337 72.0
YHH2_k127_1309385_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 317.0
YHH2_k127_1309385_1 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000002998 113.0
YHH2_k127_1309385_2 binds to the 23S rRNA K02921 - - 0.0000000000000000002914 90.0
YHH2_k127_1309385_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000005015 76.0
YHH2_k127_1309385_4 Belongs to the UPF0147 family K09721 - - 0.000000008589 59.0
YHH2_k127_1309385_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000006057 49.0
YHH2_k127_1309385_6 Mechanosensitive ion channel K16052 - - 0.0001376 51.0
YHH2_k127_131328_0 PFAM Oligosaccharyl transferase STT3 subunit K21306 - 2.4.99.21 0.000000000000000000000000000007895 137.0
YHH2_k127_131880_0 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005006 278.0
YHH2_k127_131880_1 Protein of unknown function (DUF456) K09793 - - 0.0000000001734 68.0
YHH2_k127_131880_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0000000002306 66.0
YHH2_k127_1411000_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 438.0
YHH2_k127_1411000_1 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000001251 126.0
YHH2_k127_1411000_2 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.000000000000000000000001666 111.0
YHH2_k127_1411000_3 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.000000000000000000001795 102.0
YHH2_k127_1441975_0 protein catabolic process K03420,K13525,K17681 - - 0.00000000000000000000000000000000496 145.0
YHH2_k127_156337_0 Diguanylate cyclase - - - 0.000000000000000000000000000008807 129.0
YHH2_k127_156337_1 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000003612 88.0
YHH2_k127_156337_2 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000003142 79.0
YHH2_k127_167930_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 366.0
YHH2_k127_167930_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000004045 179.0
YHH2_k127_167930_2 PFAM DNA polymerase, beta domain protein region - - - 0.0000000000000000000000000001886 124.0
YHH2_k127_167930_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000005258 92.0
YHH2_k127_167930_4 Protein of unknown function (DUF2683) - - - 0.000000000000000003686 87.0
YHH2_k127_167930_5 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000002984 83.0
YHH2_k127_167930_6 addiction module toxin, RelE StbE family - - - 0.00000000002068 67.0
YHH2_k127_1702378_0 SMART Elongator protein 3 MiaB NifB K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 428.0
YHH2_k127_1702378_1 Cation transporter/ATPase, N-terminus - - - 0.00007439 46.0
YHH2_k127_1702893_0 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000004504 193.0
YHH2_k127_1702893_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000002892 55.0
YHH2_k127_1702893_2 - - - - 0.00001036 48.0
YHH2_k127_1726132_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 8.027e-233 748.0
YHH2_k127_1726132_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000001755 83.0
YHH2_k127_1726132_2 Protein of unknown function (DUF424) K09148 - - 0.0000000000000002705 81.0
YHH2_k127_181186_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 389.0
YHH2_k127_181186_1 MazG-like family - - - 0.00000000000000002689 87.0
YHH2_k127_1885124_0 DNA-directed RNA polymerase, subunit E K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000005284 190.0
YHH2_k127_1885124_1 Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.000000000000000000004514 97.0
YHH2_k127_1885124_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002641 88.0
YHH2_k127_1885124_3 archaeal coiled-coil protein - - - 0.000000000000001726 87.0
YHH2_k127_1885124_4 Fcf1 K07158 - - 0.000000000000003027 81.0
YHH2_k127_1885124_5 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000001008 75.0
YHH2_k127_1885124_6 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000002223 60.0
YHH2_k127_1885124_7 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000002012 59.0
YHH2_k127_19629_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002366 207.0
YHH2_k127_19629_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000009077 176.0
YHH2_k127_19629_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000009693 163.0
YHH2_k127_19629_3 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.00000000008473 64.0
YHH2_k127_19629_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00007601 50.0
YHH2_k127_2007298_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000002344 99.0
YHH2_k127_2007298_1 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.00000000000000004649 83.0
YHH2_k127_2008609_0 aspartate--ammonia ligase K01914 - 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 364.0
YHH2_k127_2008609_1 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.00000000000000000000000000000000000000000005564 164.0
YHH2_k127_2008609_2 Archaeal TRASH domain - - - 0.00005571 47.0
YHH2_k127_2044910_0 helicase K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000006244 244.0
YHH2_k127_2044910_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000003721 87.0
YHH2_k127_2044910_2 Leishmanolysin - - - 0.00003071 56.0
YHH2_k127_2048752_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 412.0
YHH2_k127_2048752_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000009368 86.0
YHH2_k127_2048752_2 PFAM Diphthamide synthesis DPH2 protein K07561 GO:0006417,GO:0006448,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032268,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:2000112,GO:2000765 2.5.1.108 0.00000000000002406 76.0
YHH2_k127_209089_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 619.0
YHH2_k127_2127842_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 582.0
YHH2_k127_2127842_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000002444 173.0
YHH2_k127_2127842_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001415 143.0
YHH2_k127_2127842_4 membrane - - - 0.00000000000004522 79.0
YHH2_k127_2179652_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 477.0
YHH2_k127_2179652_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 462.0
YHH2_k127_2179652_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 388.0
YHH2_k127_2179652_3 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000368 284.0
YHH2_k127_2179652_4 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000001474 116.0
YHH2_k127_2179652_5 Glutaredoxin - - - 0.000000000000000000001587 96.0
YHH2_k127_2179652_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0003166 44.0
YHH2_k127_2296423_0 NUDIX domain K08310 - 3.6.1.67 0.0000000000000001578 85.0
YHH2_k127_2296423_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000005181 59.0
YHH2_k127_2355463_0 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003494 275.0
YHH2_k127_2355463_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002715 230.0
YHH2_k127_2355463_2 Translin family - - - 0.00000000000000000000816 97.0
YHH2_k127_2355463_3 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759 - 6.1.1.23 0.0000000000000006306 82.0
YHH2_k127_2411570_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000002302 127.0
YHH2_k127_2411570_1 glycosyl transferase family 2 - - - 0.000000000000000000000000001165 124.0
YHH2_k127_2483492_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000005202 270.0
YHH2_k127_2554592_0 TIGRFAM RecB family nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000001144 230.0
YHH2_k127_2554592_1 MarC family integral membrane protein K05595 - - 0.00000002586 57.0
YHH2_k127_2653083_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 342.0
YHH2_k127_2653083_1 response regulator - - - 0.00000000000000000000000000000000006608 145.0
YHH2_k127_2653083_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000005622 55.0
YHH2_k127_2653800_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 360.0
YHH2_k127_2653800_1 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000005898 139.0
YHH2_k127_2653800_2 COG1994 Zn-dependent proteases - - - 0.000000000001688 75.0
YHH2_k127_2679428_0 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 3.849e-265 832.0
YHH2_k127_2679428_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000001065 183.0
YHH2_k127_2679428_2 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000002716 113.0
YHH2_k127_2679428_3 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000001131 66.0
YHH2_k127_2679603_0 Beta-Casp domain K07041 - - 0.00000000000000000000000000000000000000000000000000000002171 201.0
YHH2_k127_2679603_1 CYTH - - - 0.00000000000000000003649 96.0
YHH2_k127_2685534_0 PFAM proteinase inhibitor I4 serpin K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 376.0
YHH2_k127_2685534_1 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000188 289.0
YHH2_k127_2685534_2 DHHA2 domain protein K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000006402 233.0
YHH2_k127_2685534_3 Aminoglycoside-2''-adenylyltransferase K19545 - - 0.00000009391 60.0
YHH2_k127_2794266_0 PFAM Glycosyl transferases group 1 K19002 - 2.4.1.337 0.000000000000000000000004232 115.0
YHH2_k127_2794266_1 proteins, LmbE homologs K01463 - - 0.0000000000002419 78.0
YHH2_k127_2810656_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.726e-229 728.0
YHH2_k127_2833034_0 galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000001004 207.0
YHH2_k127_2910236_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 448.0
YHH2_k127_2910236_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000003573 245.0
YHH2_k127_2910236_2 Phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000003208 216.0
YHH2_k127_2910236_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000004419 91.0
YHH2_k127_2910236_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000008634 77.0
YHH2_k127_2963438_0 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases - - - 0.000000000000000000000000000000000000000000002065 175.0
YHH2_k127_2963438_1 Domain of unknown function (DUF4416) - - - 0.0000000000004391 72.0
YHH2_k127_3009106_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 343.0
YHH2_k127_3009106_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000004615 142.0
YHH2_k127_3107840_0 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000009917 231.0
YHH2_k127_3107840_1 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000012 155.0
YHH2_k127_3107840_2 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000001117 121.0
YHH2_k127_3107840_3 Putative ATP-dependant zinc protease - - - 0.0000005596 56.0
YHH2_k127_3125911_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 435.0
YHH2_k127_3125911_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 323.0
YHH2_k127_3152447_0 3'-5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.000000000000000000005283 98.0
YHH2_k127_3152447_1 binds to the 23S rRNA K02929 - - 0.000000000000318 73.0
YHH2_k127_3152447_2 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.000000009094 61.0
YHH2_k127_3152447_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000005895 55.0
YHH2_k127_3152447_4 protein conserved in archaea K09723 - - 0.000006103 57.0
YHH2_k127_3164646_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 611.0
YHH2_k127_3164646_1 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000005366 210.0
YHH2_k127_3164646_2 PFAM S-layer - - - 0.000000000000000000000000000000000000000000000000006258 192.0
YHH2_k127_3164646_3 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000412 166.0
YHH2_k127_3164646_4 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000358 78.0
YHH2_k127_3206495_0 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000004276 107.0
YHH2_k127_3206495_1 PFAM HEPN domain protein - - - 0.0000008391 57.0
YHH2_k127_3206495_2 filamentous haemagglutinin family outer membrane protein K15125 - - 0.000001957 55.0
YHH2_k127_3206495_3 PIN domain - - - 0.0005378 48.0
YHH2_k127_3215693_0 UPF0313 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 423.0
YHH2_k127_3267851_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000208 94.0
YHH2_k127_3267851_1 Protein of unknown function (DUF4013) - - - 0.0000006313 59.0
YHH2_k127_3313170_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 336.0
YHH2_k127_3313170_1 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001017 243.0
YHH2_k127_3317808_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000003679 206.0
YHH2_k127_3317808_1 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000003845 56.0
YHH2_k127_3317808_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000186 48.0
YHH2_k127_3404911_0 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 428.0
YHH2_k127_3404911_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 387.0
YHH2_k127_3404911_2 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000006832 186.0
YHH2_k127_3404911_3 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000001369 176.0
YHH2_k127_3404911_4 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000004585 85.0
YHH2_k127_3405039_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 318.0
YHH2_k127_3405039_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003113 280.0
YHH2_k127_3405039_2 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000001141 185.0
YHH2_k127_3405039_3 SMART KH domain protein K06961 - - 0.00000000000000000000000000000000000000002173 160.0
YHH2_k127_3434234_0 ERCC4 domain K10896 - - 5.866e-195 630.0
YHH2_k127_3434234_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005189 284.0
YHH2_k127_3434234_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000482 271.0
YHH2_k127_3434234_3 PFAM LemA - - - 0.00000000000000000000000000000000000000000000000000002132 194.0
YHH2_k127_3434234_4 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000004636 59.0
YHH2_k127_3453472_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000002181 246.0
YHH2_k127_3453472_1 - - - - 0.000000007377 62.0
YHH2_k127_3495752_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.746e-262 820.0
YHH2_k127_3507965_0 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000008392 201.0
YHH2_k127_3507965_1 Protein of unknown function (DUF1648) - - - 0.000000000000000000000000000000000005372 144.0
YHH2_k127_3507965_2 - - - - 0.0002378 45.0
YHH2_k127_3541425_0 Transcriptional regulator, AsnC family K03719 - - 0.000000001169 69.0
YHH2_k127_3541425_1 helix_turn_helix ASNC type K03718 - - 0.0000004915 61.0
YHH2_k127_3613853_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 554.0
YHH2_k127_3646907_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000015 218.0
YHH2_k127_3646907_1 Thioredoxin - - - 0.00000000000000000000000000000000006508 142.0
YHH2_k127_3646907_2 Thioredoxin - - - 0.000000002863 58.0
YHH2_k127_3654691_0 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000001126 109.0
YHH2_k127_3654691_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000002045 108.0
YHH2_k127_3654691_2 Peptidase U32 K08303 - - 0.000000000004048 67.0
YHH2_k127_3654691_3 Tetratricopeptide - - - 0.00001992 49.0
YHH2_k127_3686117_0 Protein of unknown function (DUF2937) - - - 0.000000000000000000000003094 109.0
YHH2_k127_3686117_1 COG3911 Predicted ATPase - - - 0.0000000000000000000004758 102.0
YHH2_k127_3686117_2 Protein tyrosine kinase - - - 0.0004248 49.0
YHH2_k127_3686117_3 Domain of unknown function (DUF362) - - - 0.0004518 52.0
YHH2_k127_3687621_0 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000001665 164.0
YHH2_k127_3687621_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000003229 123.0
YHH2_k127_3687621_3 PIN domain - - - 0.0000001767 58.0
YHH2_k127_3689177_0 Psort location Cytoplasmic, score 8.87 K02503 - - 0.000000000000000000000000953 115.0
YHH2_k127_3689177_1 PFAM histidine triad (HIT) protein K02503 - - 0.0000000000000000000001404 104.0
YHH2_k127_3689177_2 Rhs Family - - - 0.000000000001605 79.0
YHH2_k127_3689177_3 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000004006 64.0
YHH2_k127_3811859_0 segregation and condensation protein B K06024 - - 0.0000000000000000001274 95.0
YHH2_k127_3968480_0 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 300.0
YHH2_k127_3968480_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000002321 231.0
YHH2_k127_3991268_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 349.0
YHH2_k127_3991268_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0001744 49.0
YHH2_k127_3998218_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 347.0
YHH2_k127_3998218_1 TRAM domain - - - 0.000000000000000004031 88.0
YHH2_k127_4039566_0 GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006477 245.0
YHH2_k127_4039566_1 Zn-ribbon containing protein K07163 - - 0.00000000000001289 79.0
YHH2_k127_4039566_2 - - - - 0.0000000004979 63.0
YHH2_k127_4039566_3 protein conserved in archaea K09743 - - 0.000000006694 62.0
YHH2_k127_4091700_0 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001773 263.0
YHH2_k127_4091700_1 ZPR1-like zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000003417 135.0
YHH2_k127_4114082_0 Pheromone shutdown protein - - - 0.00000000000000000000000000000000002044 146.0
YHH2_k127_4114082_1 PHP domain protein - - - 0.00000000000000000000000000000000002179 143.0
YHH2_k127_4114082_2 PFAM acid phosphatase vanadium-dependent haloperoxidase related K09775 - - 0.0000000002743 66.0
YHH2_k127_4114082_3 transcriptional - - - 0.00000009134 62.0
YHH2_k127_4114082_4 PRC-barrel domain - - - 0.00002038 50.0
YHH2_k127_4114082_5 PFAM peptidase M50 - - - 0.000224 48.0
YHH2_k127_4118816_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 518.0
YHH2_k127_4118816_1 cheY-homologous receiver domain - - - 0.0001404 53.0
YHH2_k127_4123343_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000005735 175.0
YHH2_k127_4124369_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001276 263.0
YHH2_k127_4127301_0 DNA recombination-mediator protein A - - - 0.00000000000000000000000000000000000000000000000000000000000000000005138 243.0
YHH2_k127_4127301_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000862 64.0
YHH2_k127_4131766_0 Belongs to the MCM family K10726 - - 0.00000000000000000000000000000000000000001778 159.0
YHH2_k127_4131766_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000003459 74.0
YHH2_k127_4131766_2 helicase activity - - - 0.00000000002806 72.0
YHH2_k127_4131766_3 PQQ-like domain - - - 0.000447 53.0
YHH2_k127_4138616_0 phosphopyruvate hydratase activity K01689 GO:0000003,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0019953,GO:0022414,GO:0044424,GO:0044464,GO:0044703,GO:0051704 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 500.0
YHH2_k127_4138616_1 SMART Elongator protein 3 MiaB NifB K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006116 262.0
YHH2_k127_4138616_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000001224 184.0
YHH2_k127_4138616_3 PAC2 family K07159 - - 0.00000000000000000000000000000000000001484 154.0
YHH2_k127_4138616_4 transmembrane transport - - - 0.0000000000000002524 87.0
YHH2_k127_4138616_5 Ribosomal protein S27E K02978 - - 0.0000000000000003099 80.0
YHH2_k127_4138616_6 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000006353 50.0
YHH2_k127_4157249_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 1.111e-213 679.0
YHH2_k127_4157249_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 423.0
YHH2_k127_4157249_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000002478 73.0
YHH2_k127_4157249_3 Domain of Unknown Function with PDB structure (DUF3850) - - - 0.00003883 50.0
YHH2_k127_4188168_0 von Willebrand factor (vWF) type A domain K07114 - - 0.00000002298 62.0
YHH2_k127_4192778_0 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000007732 174.0
YHH2_k127_4192778_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000001964 59.0
YHH2_k127_4192778_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0009591 51.0
YHH2_k127_4233772_0 GTPase of K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 408.0
YHH2_k127_4233772_1 Diguanylate cyclase with GAF sensor - - - 0.00000000000000000000000000000000000000000000001954 190.0
YHH2_k127_4317577_0 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000004341 95.0
YHH2_k127_4317577_1 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000001364 68.0
YHH2_k127_4317577_2 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.0000000003042 64.0
YHH2_k127_4378646_0 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000002297 170.0
YHH2_k127_4378646_1 replication factor A K07466 - - 0.000000000000000000000000000000001231 142.0
YHH2_k127_4378646_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000002521 79.0
YHH2_k127_4396997_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 359.0
YHH2_k127_4396997_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000419 171.0
YHH2_k127_4396997_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000001358 176.0
YHH2_k127_4396997_3 Transcriptional regulator - - - 0.00000001114 65.0
YHH2_k127_4427449_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 387.0
YHH2_k127_4427449_1 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
YHH2_k127_4454478_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000002532 217.0
YHH2_k127_4492522_0 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000001353 239.0
YHH2_k127_4492522_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000881 211.0
YHH2_k127_4607109_0 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002867 280.0
YHH2_k127_4607109_1 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000002834 247.0
YHH2_k127_4607109_2 MacB-like periplasmic core domain K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000004134 128.0
YHH2_k127_4607109_3 COG1361 S-layer domain - - - 0.000000000000000000000000006208 125.0
YHH2_k127_4764983_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 423.0
YHH2_k127_4764983_1 transcription regulator activity - - - 0.00001802 56.0
YHH2_k127_4774901_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001776 181.0
YHH2_k127_4774901_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001231 174.0
YHH2_k127_4774901_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000002137 75.0
YHH2_k127_4774901_11 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000002199 63.0
YHH2_k127_4774901_12 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000008974 54.0
YHH2_k127_4774901_13 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00001262 49.0
YHH2_k127_4774901_2 Binds the lower part of the 30S subunit head K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001585 178.0
YHH2_k127_4774901_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000009009 170.0
YHH2_k127_4774901_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000001212 159.0
YHH2_k127_4774901_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000005113 155.0
YHH2_k127_4774901_6 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000001876 128.0
YHH2_k127_4774901_7 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000009042 129.0
YHH2_k127_4774901_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000009346 100.0
YHH2_k127_4774901_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000001176 92.0
YHH2_k127_4873761_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 328.0
YHH2_k127_4873761_1 cellulase activity K01387 - 3.4.24.3 0.0000000000006531 81.0
YHH2_k127_4873761_2 Protein of unknown function (DUF1461) - - - 0.0000002578 60.0
YHH2_k127_4961483_0 of the AAA class - - - 0.00000000007736 75.0
YHH2_k127_497133_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000004816 194.0
YHH2_k127_497133_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001093 150.0
YHH2_k127_5079127_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000003327 170.0
YHH2_k127_509773_0 oxidized base lesion DNA N-glycosylase activity - - - 0.00000000000000000000000000006084 121.0
YHH2_k127_509773_1 PFAM DNA polymerase, beta domain protein region - - - 0.000000000000000000000000001986 129.0
YHH2_k127_51241_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000001692 173.0
YHH2_k127_51241_1 nitroreductase K04719 - 1.13.11.79 0.000000000000000000000000000000000000005197 154.0
YHH2_k127_5133635_0 PFAM regulatory protein AsnC Lrp family K03718 - - 0.0000000002787 67.0
YHH2_k127_5233130_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000007887 199.0
YHH2_k127_5233130_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000004004 138.0
YHH2_k127_5233130_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000001381 130.0
YHH2_k127_5233130_3 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003428 124.0
YHH2_k127_5233130_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000002696 120.0
YHH2_k127_5283089_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 393.0
YHH2_k127_5320780_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 406.0
YHH2_k127_5320780_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000001111 139.0
YHH2_k127_5320780_2 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000005312 65.0
YHH2_k127_5505925_0 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000003534 103.0
YHH2_k127_5505925_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000006658 69.0
YHH2_k127_5505925_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K06931 - - 0.00006113 49.0
YHH2_k127_5520067_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 429.0
YHH2_k127_5571961_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000008511 136.0
YHH2_k127_5571961_1 - - - - 0.00000000000000000000000000001157 131.0
YHH2_k127_5571961_3 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0004591 45.0
YHH2_k127_5632625_0 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000004518 197.0
YHH2_k127_5632625_1 4Fe-4S single cluster domain K07129 - - 0.0000000000000000000000000000000000000000000000000005741 190.0
YHH2_k127_5632625_2 hydrolase, TatD K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000767 173.0
YHH2_k127_5643060_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 349.0
YHH2_k127_5643060_1 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003657 269.0
YHH2_k127_5660401_0 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000272 81.0
YHH2_k127_5660401_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000007465 63.0
YHH2_k127_5697094_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 345.0
YHH2_k127_5697094_1 sigma factor antagonist activity K04757,K06379,K08282 - 2.7.11.1 0.0007487 49.0
YHH2_k127_5817049_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000002036 216.0
YHH2_k127_5817049_1 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.0000000000000000000000000002381 119.0
YHH2_k127_5921169_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000001232 121.0
YHH2_k127_5921169_1 COG0150 Phosphoribosylaminoimidazole (AIR) synthetase K01933 - 6.3.3.1 0.0000000000000000004216 98.0
YHH2_k127_6001251_1 Transcriptional regulator - - - 0.00000000000000000007331 99.0
YHH2_k127_6001251_2 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000007312 51.0
YHH2_k127_6037293_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 363.0
YHH2_k127_6037293_1 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004651 280.0
YHH2_k127_6037293_2 Von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000006352 226.0
YHH2_k127_6037293_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000007977 115.0
YHH2_k127_6037293_4 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.00000000001076 70.0
YHH2_k127_6037293_5 Belongs to the PDCD5 family K06875 - - 0.0000004895 55.0
YHH2_k127_605367_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 353.0
YHH2_k127_605367_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000002113 208.0
YHH2_k127_605367_2 Rubrerythrin K19824 - - 0.0000000000000000000000000000000004264 138.0
YHH2_k127_605367_3 protein maturation K02224,K13628,K15724 - 6.3.5.11,6.3.5.9 0.0000000000000005807 81.0
YHH2_k127_605367_4 Rubrerythrin - - - 0.000000000005141 66.0
YHH2_k127_6132279_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002957 294.0
YHH2_k127_6132279_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005648 259.0
YHH2_k127_6132279_2 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K07533 - 5.2.1.8 0.000000000000000000000000000000000000001031 161.0
YHH2_k127_6132279_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.000000002796 64.0
YHH2_k127_6149534_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 621.0
YHH2_k127_6172997_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003122 287.0
YHH2_k127_6172997_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000001033 119.0
YHH2_k127_6263724_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000004648 225.0
YHH2_k127_6263724_1 TIGRFAM RNA methyltransferase, TrmH - - - 0.0000000000000000000000000000000000000000002993 166.0
YHH2_k127_6263724_2 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000003087 135.0
YHH2_k127_6297813_0 PFAM acid phosphatase (Class B) - - - 0.00000000000000000000000000000000000000000000000000000000000006513 222.0
YHH2_k127_6297813_1 Glycosyl hydrolases family 16 - - - 0.0000000000001278 78.0
YHH2_k127_6438829_0 - - - - 0.000000000000000000005805 105.0
YHH2_k127_6438829_1 Transcriptional regulator K07722 - - 0.0009181 45.0
YHH2_k127_6474964_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000001403 199.0
YHH2_k127_6474964_1 Belongs to the UPF0251 family - - - 0.00000000000000000000000000000000006037 136.0
YHH2_k127_6474964_2 - - - - 0.0000000000000000000000001233 115.0
YHH2_k127_6517195_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 350.0
YHH2_k127_6517195_1 Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000256 74.0
YHH2_k127_6574739_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000008246 196.0
YHH2_k127_6574739_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000001225 51.0
YHH2_k127_6590816_0 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 355.0
YHH2_k127_6590816_1 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 323.0
YHH2_k127_6590816_2 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000151 248.0
YHH2_k127_6590816_3 ABC transporter K01990,K09691 - - 0.000000000000000000000000000000000000000000000000000000000000001292 227.0
YHH2_k127_6590816_4 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000003637 185.0
YHH2_k127_6590816_5 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000006579 152.0
YHH2_k127_6590816_6 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000001101 86.0
YHH2_k127_6590816_7 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain - - - 0.0000000184 59.0
YHH2_k127_6770863_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 344.0
YHH2_k127_6770863_1 COG0639 Diadenosine tetraphosphatase and related - - - 0.000000000000000000000000000000000000000932 159.0
YHH2_k127_6770863_2 Domain of unknown function (DUF4349) - - - 0.00003746 53.0
YHH2_k127_6873687_0 Protein-export membrane protein SecD K03072 - - 0.0000000000000000000000000000000000000000000000000000000002339 217.0
YHH2_k127_6873687_1 Multidrug Resistance protein - - - 0.000000126 56.0
YHH2_k127_6873687_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0008255 49.0
YHH2_k127_6940599_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 413.0
YHH2_k127_6940599_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001144 129.0
YHH2_k127_6940599_2 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001563 99.0
YHH2_k127_6940599_3 binds to the 23S rRNA K02876 - - 0.0000000000000002509 86.0
YHH2_k127_6940599_4 Integral membrane protein DUF106 - - - 0.0000001373 62.0
YHH2_k127_694507_0 Psort location Cytoplasmic, score - - - 0.000000002258 64.0
YHH2_k127_6964153_0 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000001567 194.0
YHH2_k127_6964153_1 (ABC) transporter K02050 - - 0.0000000000000000000000000000000000000008314 154.0
YHH2_k127_6964153_2 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000044 138.0
YHH2_k127_698591_0 Glycosyl hydrolases family 15 K07190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 308.0
YHH2_k127_698591_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000002839 183.0
YHH2_k127_698591_2 Glycogen debranching enzyme N terminal - - - 0.00002049 55.0
YHH2_k127_7135625_0 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000004706 169.0
YHH2_k127_7379291_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.81e-251 810.0
YHH2_k127_7554922_0 PFAM HhH-GPD family protein K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
YHH2_k127_7554922_1 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000003651 201.0
YHH2_k127_763214_0 tRNA (Uracil-5-)-methyltransferase - - - 0.000000000000000000000000000000000000000000000002993 179.0
YHH2_k127_769741_0 K homology RNA-binding domain K06865 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 578.0
YHH2_k127_769741_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 391.0
YHH2_k127_769741_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000004013 72.0
YHH2_k127_7703873_0 CRS1_YhbY K07574 - - 0.00000001073 60.0
YHH2_k127_7892906_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 392.0
YHH2_k127_7892906_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000001121 237.0
YHH2_k127_7892906_2 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000005583 223.0
YHH2_k127_7892906_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000001241 220.0
YHH2_k127_7977175_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000008222 229.0
YHH2_k127_7977175_1 MGS-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000048 227.0
YHH2_k127_7977175_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.0000000000000000000000002294 114.0
YHH2_k127_7979938_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000296 279.0
YHH2_k127_7983211_0 Psort location Cytoplasmic, score 8.87 - - - 0.00000000000000000000000000002423 125.0
YHH2_k127_7983211_1 - - - - 0.0000000000000000000000000001203 126.0
YHH2_k127_8022528_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 317.0
YHH2_k127_8064188_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 346.0
YHH2_k127_8064188_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004518,GO:0004550,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016787,GO:0016788,GO:0018995,GO:0019205,GO:0019538,GO:0019637,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034641,GO:0036211,GO:0042025,GO:0043170,GO:0043412,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046483,GO:0046777,GO:0046939,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072527,GO:0090304,GO:0090305,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000003786 166.0
YHH2_k127_8064188_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001179 122.0
YHH2_k127_8064188_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000001618 88.0
YHH2_k127_8064188_4 Binds to the 23S rRNA K02896 - - 0.0000000000001043 74.0
YHH2_k127_8093751_0 Belongs to the MCM family K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 376.0
YHH2_k127_8093751_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000005177 194.0
YHH2_k127_8117560_0 Endonuclease I - - - 0.000466 53.0
YHH2_k127_8190353_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001988 280.0
YHH2_k127_8190353_1 Domain of unknown function (DUF4347) - - - 0.00002251 57.0
YHH2_k127_8190353_2 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00007884 45.0
YHH2_k127_8214838_0 Transglutaminase-like - - - 0.000000000000000004879 99.0
YHH2_k127_8218577_0 Phosphate uptake regulator - - - 0.000000001378 69.0
YHH2_k127_8218577_1 radical SAM domain protein - - - 0.00003806 56.0
YHH2_k127_8222259_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 5.179e-223 704.0
YHH2_k127_8344607_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000004924 149.0
YHH2_k127_8344607_1 Involved in the tonB-independent uptake of proteins - - - 0.000002897 55.0
YHH2_k127_8344661_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 334.0
YHH2_k127_8344661_1 ABC transporter, ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000001391 199.0
YHH2_k127_8344661_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000004429 177.0
YHH2_k127_8344661_3 PFAM helix-turn-helix domain protein K03627 - - 0.00000000000000001483 88.0
YHH2_k127_8344661_4 mRNA catabolic process - - - 0.000000000002489 74.0
YHH2_k127_8371262_0 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000004641 111.0
YHH2_k127_8371262_1 Belongs to the ParA family K03609 - - 0.000000000000000000000001196 108.0
YHH2_k127_8387697_0 - K15383 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0042802,GO:0044425 - 0.00000436 52.0
YHH2_k127_8419280_0 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.000000000000000000000000000000008858 128.0
YHH2_k127_8419280_1 NUDIX domain - - - 0.000000000000001096 81.0
YHH2_k127_8421675_0 Tetrapyrrole (Corrin/Porphyrin) Methylases K00586 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:2000112,GO:2000765 2.1.1.314 0.0000000000000000000000000000000000000000000000000000000000000000000000003434 255.0
YHH2_k127_8421675_1 Metal dependent phosphohydrolase K09163 - - 0.0002773 49.0
YHH2_k127_8542947_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000003207 208.0
YHH2_k127_8548866_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.665e-236 744.0
YHH2_k127_8548866_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000003808 237.0
YHH2_k127_8548866_2 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000004742 168.0
YHH2_k127_8548866_3 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000001877 173.0
YHH2_k127_8548866_4 COG1522 Transcriptional regulators - - - 0.000000004553 60.0
YHH2_k127_8548866_5 Transglutaminase-like superfamily - - - 0.00000002085 64.0
YHH2_k127_8592972_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000002013 185.0
YHH2_k127_8592972_1 SpoVT / AbrB like domain - - - 0.0000000000000006363 88.0
YHH2_k127_8753371_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 385.0
YHH2_k127_8753371_1 peptidase M29 K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 322.0
YHH2_k127_8753371_2 Conserved hypothetical protein 95 K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000001083 220.0
YHH2_k127_8753371_3 spore germination K08978 - - 0.00009621 51.0
YHH2_k127_8806631_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 374.0
YHH2_k127_8806631_1 Transcriptional regulator, BadM Rrf2 family - - - 0.0000000000000000000000000000000000000000007 161.0
YHH2_k127_8806631_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000001473 158.0
YHH2_k127_8895065_0 PFAM regulatory protein AsnC Lrp family K03718 - - 0.0000000001135 68.0
YHH2_k127_8895065_1 Pentapeptide repeat protein - - - 0.0000001093 63.0
YHH2_k127_8907215_0 Transcriptional regulator, TrmB - - - 0.0000001153 62.0
YHH2_k127_9007079_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000001582 263.0
YHH2_k127_9007079_1 Hydrolase, NUDIX family - - - 0.0000000000000000001281 93.0
YHH2_k127_9007079_2 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0008316 44.0
YHH2_k127_9007325_0 - - - - 0.000000000000000000000000000000002157 132.0
YHH2_k127_9007325_1 - - - - 0.00000000000000000000001518 102.0
YHH2_k127_9007325_2 - - - - 0.0000000000000000399 85.0
YHH2_k127_9007325_3 - - - - 0.00002134 51.0
YHH2_k127_9007325_4 Sigma-54 interaction domain K07713,K07714 - - 0.00008444 52.0
YHH2_k127_9196635_0 PFAM glycosyl transferase family 39 K14340 - - 0.0000000000000000000000000000000000000000000000000000008594 209.0
YHH2_k127_9256321_0 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000002803 164.0
YHH2_k127_9256321_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate - - - 0.00000000000000000000000000000000003476 140.0
YHH2_k127_9256321_2 Thymidylate kinase K13809 GO:0002237,GO:0003674,GO:0003824,GO:0004127,GO:0004550,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006165,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009605,GO:0009607,GO:0009617,GO:0009987,GO:0010033,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0032496,GO:0033862,GO:0033993,GO:0034641,GO:0034654,GO:0042221,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0055086,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071396,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701 2.7.4.14 0.00000000000000001913 89.0
YHH2_k127_9334209_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1113.0
YHH2_k127_9334209_1 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001614 257.0
YHH2_k127_9334209_2 DeoC/LacD family aldolase K11645,K16305 - 2.2.1.11,4.1.2.13 0.00000000000000000000000000000000000000004473 155.0
YHH2_k127_9334209_3 methylase K07446 - 2.1.1.213 0.00000000000000000000114 100.0
YHH2_k127_9335557_0 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000427 135.0
YHH2_k127_9335557_1 CAAX protease self-immunity K07052 - - 0.00000001413 66.0
YHH2_k127_9356417_0 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 361.0
YHH2_k127_9356417_1 antiporter K07301 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0008150,GO:0008273,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015081,GO:0015085,GO:0015267,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022803,GO:0022804,GO:0022821,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030955,GO:0031224,GO:0031226,GO:0031402,GO:0031420,GO:0034220,GO:0035725,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070588,GO:0070838,GO:0071804,GO:0071805,GO:0071944,GO:0072503,GO:0072507,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516 - 0.00000006283 61.0
YHH2_k127_9493632_0 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000004522 98.0
YHH2_k127_9493632_1 Domain of unknown function (DUF378) K09779 - - 0.00000000000002188 75.0
YHH2_k127_9493632_2 Protein of unknown function DUF58 - - - 0.00004802 47.0
YHH2_k127_9496562_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 291.0
YHH2_k127_9496562_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000847 287.0
YHH2_k127_9500173_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000001069 250.0
YHH2_k127_9500173_1 Flavin reductase like domain - - - 0.0000000000000000000000006202 110.0
YHH2_k127_95310_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 316.0
YHH2_k127_95310_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000006276 60.0
YHH2_k127_95310_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0002641 50.0
YHH2_k127_9598966_0 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000001277 168.0
YHH2_k127_9598966_1 Transcriptional regulator, TrmB - - - 0.0000000000000000000000002675 115.0
YHH2_k127_9608706_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000001745 139.0
YHH2_k127_9608706_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000000000002054 81.0
YHH2_k127_9608706_2 Stage II sporulation protein M K06384 - - 0.00006518 54.0
YHH2_k127_9674625_0 Secondary thiamine-phosphate synthase enzyme - - - 0.0000000000000000000000000000000000000000000000000009334 188.0
YHH2_k127_9674625_1 Cupin 2, conserved barrel domain protein - - - 0.000000000005866 69.0
YHH2_k127_9674625_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.000001985 59.0
YHH2_k127_975109_0 TCP-1/cpn60 chaperonin family K22447 - - 6.955e-221 697.0
YHH2_k127_975109_1 AAA domain K00945 - 2.7.4.25 0.00000000000000000000009731 102.0
YHH2_k127_9794581_0 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 449.0
YHH2_k127_9794581_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 384.0
YHH2_k127_9794581_2 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000005563 158.0
YHH2_k127_9794581_3 COG1209 dTDP-glucose pyrophosphorylase K00973 - 2.7.7.24 0.0000000000000000000006546 100.0
YHH2_k127_9794581_4 nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000005251 89.0
YHH2_k127_9829009_0 N(2),N(2)-dimethylguanosine tRNA methyltransferase K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000003328 254.0
YHH2_k127_9829009_1 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000759 170.0
YHH2_k127_9842255_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000003889 179.0
YHH2_k127_9842255_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000005998 102.0