Overview

ID MAG04571
Name YHH3_bin.34
Sample SMP0123
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species
Assembly information
Completeness (%) 93.39
Contamination (%) 0.76
GC content (%) 44.0
N50 (bp) 32,672
Genome size (bp) 2,000,450

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1656

Gene name Description KEGG GOs EC E-value Score Sequence
YHH3_k127_10028528_0 Psort location Cytoplasmic, score - - - 0.0 1495.0
YHH3_k127_10028528_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 2.729e-197 625.0
YHH3_k127_10028528_10 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436,K14126 - 1.12.1.2,1.8.98.5 0.0000000000000000000000000000000000000000000000000000001374 197.0
YHH3_k127_10028528_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000006269 186.0
YHH3_k127_10028528_12 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000001403 170.0
YHH3_k127_10028528_13 spore germination K03605 - - 0.00000000000000000000003403 105.0
YHH3_k127_10028528_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 314.0
YHH3_k127_10028528_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 302.0
YHH3_k127_10028528_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K16950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 297.0
YHH3_k127_10028528_5 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000968 287.0
YHH3_k127_10028528_6 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003006 271.0
YHH3_k127_10028528_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001598 250.0
YHH3_k127_10028528_8 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000002754 219.0
YHH3_k127_10028528_9 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000001099 200.0
YHH3_k127_10117447_0 COG3547 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000001943 230.0
YHH3_k127_10117447_1 COG3039 Transposase and inactivated derivatives, IS5 family - - - 0.000004764 58.0
YHH3_k127_10164469_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 5.037e-201 634.0
YHH3_k127_10164469_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 553.0
YHH3_k127_10164469_2 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 501.0
YHH3_k127_10164469_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 357.0
YHH3_k127_10164469_4 Patched family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001473 272.0
YHH3_k127_10164469_5 regulator of amino acid metabolism K07103 - - 0.000000000000000000000000000000000014 141.0
YHH3_k127_10164469_6 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000009257 98.0
YHH3_k127_10164469_7 Thermolysin metallopeptidase, catalytic domain K19702 - 3.4.11.24 0.0003428 55.0
YHH3_k127_10193669_0 Anion transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 359.0
YHH3_k127_10193669_1 Proton-conducting membrane transporter K05568,K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000684 252.0
YHH3_k127_10193669_10 PFAM Domain related to MnhB subunit of Na H antiporter K05566 - - 0.000002515 53.0
YHH3_k127_10193669_11 Domain of unknown function (DUF4040) - - - 0.0002039 47.0
YHH3_k127_10193669_2 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000000000000000000000000005319 163.0
YHH3_k127_10193669_3 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000006937 102.0
YHH3_k127_10193669_4 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.0000000000000000001378 93.0
YHH3_k127_10193669_5 - - - - 0.0000000000000000007445 94.0
YHH3_k127_10193669_6 TIGRFAM monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.0000000000000002549 83.0
YHH3_k127_10193669_7 - - - - 0.000000000000001204 85.0
YHH3_k127_10193669_8 Na+/H+ ion antiporter subunit K05569 - - 0.000000001651 66.0
YHH3_k127_10265436_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 325.0
YHH3_k127_10265436_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000003704 175.0
YHH3_k127_10265436_2 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000001404 173.0
YHH3_k127_10265436_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000002218 109.0
YHH3_k127_10265436_4 Subtilase family - - - 0.000000002558 71.0
YHH3_k127_10265436_5 Thymidylate synthase K00560 - 2.1.1.45 0.000001604 55.0
YHH3_k127_10265436_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0001903 51.0
YHH3_k127_10319358_0 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 326.0
YHH3_k127_10319358_2 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000001176 175.0
YHH3_k127_10319358_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000007658 177.0
YHH3_k127_10319358_4 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000009153 118.0
YHH3_k127_10432081_0 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 3.554e-238 751.0
YHH3_k127_10432081_1 pathogenesis K13669 - - 0.000000000005885 80.0
YHH3_k127_10432081_2 Domain of unknown function (DUF2341) - - - 0.000000001925 72.0
YHH3_k127_10432081_3 GDSL-like Lipase/Acylhydrolase family K06882 - - 0.0006162 53.0
YHH3_k127_1076814_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 289.0
YHH3_k127_1076814_1 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 273.0
YHH3_k127_1076814_10 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000135 78.0
YHH3_k127_1076814_11 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000479 62.0
YHH3_k127_1076814_12 - - - - 0.0004084 48.0
YHH3_k127_1076814_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000003662 228.0
YHH3_k127_1076814_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000113 199.0
YHH3_k127_1076814_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000000000008499 148.0
YHH3_k127_1076814_5 Fibronectin type III domain - - - 0.000000000000000000000000006704 126.0
YHH3_k127_1076814_6 PFAM Peptidase C1A, papain - - - 0.00000000000000000000000002139 127.0
YHH3_k127_1076814_7 - - - - 0.000000000000000000000001212 106.0
YHH3_k127_1076814_8 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.000000000000000000000007369 108.0
YHH3_k127_1076814_9 - - - - 0.0000000000001918 73.0
YHH3_k127_10824636_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1212.0
YHH3_k127_10824636_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 417.0
YHH3_k127_10824636_2 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003081 280.0
YHH3_k127_10824636_3 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001925 273.0
YHH3_k127_10824636_4 4Fe-4S dicluster domain - - - 0.000000248 53.0
YHH3_k127_109375_0 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 420.0
YHH3_k127_109375_1 PFAM PEGA domain - - - 0.0000000000000000000000000000000000004204 159.0
YHH3_k127_109375_2 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000000000005528 68.0
YHH3_k127_10967509_0 type II secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 575.0
YHH3_k127_10967509_1 type II secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 548.0
YHH3_k127_10967509_10 PFAM Flagella accessory C family protein K07822 - - 0.000004351 57.0
YHH3_k127_10967509_11 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00001653 53.0
YHH3_k127_10967509_2 PFAM Type II secretion system F domain K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 304.0
YHH3_k127_10967509_3 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000001171 156.0
YHH3_k127_10967509_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000000000000000339 154.0
YHH3_k127_10967509_5 SMART AAA ATPase K07331 - - 0.0000000000000000000000000000000000001101 150.0
YHH3_k127_10967509_6 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000002642 138.0
YHH3_k127_10967509_7 flagella protein K07327,K07328 - - 0.000000000000000000000000001602 122.0
YHH3_k127_10967509_8 Archaebacterial flagellin K07330 - - 0.000000000000000000003681 98.0
YHH3_k127_10967509_9 COG NOG14600 non supervised orthologous group - - - 0.000000000804 61.0
YHH3_k127_11116148_0 phosphate ABC transporter, inner membrane subunit PstA K02037,K02038 - - 9.078e-228 722.0
YHH3_k127_11116148_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 609.0
YHH3_k127_11116148_10 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002229 278.0
YHH3_k127_11116148_11 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
YHH3_k127_11116148_12 Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000117 254.0
YHH3_k127_11116148_13 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001453 240.0
YHH3_k127_11116148_14 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000003552 224.0
YHH3_k127_11116148_15 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000005629 182.0
YHH3_k127_11116148_16 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000007567 176.0
YHH3_k127_11116148_17 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000003001 168.0
YHH3_k127_11116148_18 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000003762 163.0
YHH3_k127_11116148_19 - K03561,K12287 - - 0.00000000000000000000000000000000000000002651 175.0
YHH3_k127_11116148_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 532.0
YHH3_k127_11116148_20 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000001135 162.0
YHH3_k127_11116148_21 TIGRFAM segregation and condensation protein B K06024 - - 0.00000000000000000000000000000000621 135.0
YHH3_k127_11116148_22 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000003466 124.0
YHH3_k127_11116148_23 parallel beta-helix repeat - - - 0.000000000000000000000000005899 126.0
YHH3_k127_11116148_24 metallopeptidase activity - - - 0.00000000000000000000004715 114.0
YHH3_k127_11116148_26 PFAM PKD domain containing protein - - - 0.0000000000002203 80.0
YHH3_k127_11116148_27 C-terminal domain of CHU protein family - - - 0.00000000002943 76.0
YHH3_k127_11116148_28 Protein of unknown function, DUF599 - - - 0.0000004169 60.0
YHH3_k127_11116148_29 deoxyhypusine monooxygenase activity - - - 0.000002216 54.0
YHH3_k127_11116148_3 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 463.0
YHH3_k127_11116148_30 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000008491 57.0
YHH3_k127_11116148_31 Biotin-protein ligase, N terminal - - - 0.00009129 55.0
YHH3_k127_11116148_32 metallopeptidase activity - - - 0.0002646 54.0
YHH3_k127_11116148_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 388.0
YHH3_k127_11116148_5 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 398.0
YHH3_k127_11116148_6 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 385.0
YHH3_k127_11116148_7 PhoU domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 366.0
YHH3_k127_11116148_8 Phosphate K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 372.0
YHH3_k127_11116148_9 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 332.0
YHH3_k127_11135401_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 4.013e-256 806.0
YHH3_k127_11135401_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 484.0
YHH3_k127_11135401_10 PFAM periplasmic copper-binding - - - 0.0000000000000000000000000003324 134.0
YHH3_k127_11135401_11 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000002566 109.0
YHH3_k127_11135401_12 Phosphoesterase PA-phosphatase - - - 0.00000000000000000007237 99.0
YHH3_k127_11135401_13 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000001143 66.0
YHH3_k127_11135401_2 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 454.0
YHH3_k127_11135401_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 304.0
YHH3_k127_11135401_4 TatD related DNase K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005023 256.0
YHH3_k127_11135401_5 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000007673 209.0
YHH3_k127_11135401_6 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.00000000000000000000000000000000000000000000000000003204 192.0
YHH3_k127_11135401_7 PAS domain - - - 0.0000000000000000000000000000000000000000000000002433 203.0
YHH3_k127_11135401_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000003548 152.0
YHH3_k127_11135401_9 Radical SAM - - - 0.00000000000000000000000000000000005582 143.0
YHH3_k127_1131217_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002787 287.0
YHH3_k127_1131217_1 - - - - 0.0000000000000000000004294 104.0
YHH3_k127_1131217_2 - - - - 0.000000000000000000004278 98.0
YHH3_k127_1131217_3 - - - - 0.000000000001688 70.0
YHH3_k127_11379304_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 514.0
YHH3_k127_11379304_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 490.0
YHH3_k127_11379304_10 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 321.0
YHH3_k127_11379304_11 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 303.0
YHH3_k127_11379304_12 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 308.0
YHH3_k127_11379304_13 Ferritin-like domain - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
YHH3_k127_11379304_14 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000000009297 215.0
YHH3_k127_11379304_15 PFAM phosphatidate cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002237 218.0
YHH3_k127_11379304_16 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000002994 216.0
YHH3_k127_11379304_17 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000401 216.0
YHH3_k127_11379304_18 Desulfoferrodoxin ferrous iron-binding domain K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000000001223 202.0
YHH3_k127_11379304_19 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000003189 203.0
YHH3_k127_11379304_2 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 466.0
YHH3_k127_11379304_20 - K07092 - - 0.00000000000000000000000000000000000000000000000000000003268 198.0
YHH3_k127_11379304_21 Ferritin-like domain K02217 - 1.16.3.2 0.0000000000000000000000000000000000000000000000000000002063 198.0
YHH3_k127_11379304_22 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000006119 187.0
YHH3_k127_11379304_23 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000221 175.0
YHH3_k127_11379304_24 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000002033 173.0
YHH3_k127_11379304_25 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.0000000000000000000000000000000000000006835 153.0
YHH3_k127_11379304_26 Rubrerythrin - - - 0.00000000000000000000000000000000000003208 148.0
YHH3_k127_11379304_27 NUDIX domain - - - 0.00000000000000000000000000000000001291 139.0
YHH3_k127_11379304_28 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000002089 138.0
YHH3_k127_11379304_29 redox protein regulator of disulfide bond formation - - - 0.000000000000000000000000000000004933 129.0
YHH3_k127_11379304_3 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 469.0
YHH3_k127_11379304_30 AraC-like ligand binding domain - - - 0.000000000000000000000000000000009568 130.0
YHH3_k127_11379304_31 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000002769 119.0
YHH3_k127_11379304_32 - - - - 0.0000000000000000000000005336 109.0
YHH3_k127_11379304_33 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000000000000000000001324 117.0
YHH3_k127_11379304_34 Polyprenyl synthetase K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000004426 108.0
YHH3_k127_11379304_35 protein conserved in archaea - - - 0.00000000000000000002172 94.0
YHH3_k127_11379304_36 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000001931 83.0
YHH3_k127_11379304_37 Rubrerythrin - - - 0.0000000000000003263 85.0
YHH3_k127_11379304_39 - K03741 - 1.20.4.1 0.0000000000003154 74.0
YHH3_k127_11379304_4 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 395.0
YHH3_k127_11379304_40 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.000000000002197 78.0
YHH3_k127_11379304_41 FIST_C - - - 0.00000000005983 72.0
YHH3_k127_11379304_43 Protein of unknown function (DUF1349) - - - 0.000000001483 69.0
YHH3_k127_11379304_44 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000004498 60.0
YHH3_k127_11379304_45 self proteolysis - - - 0.00002095 57.0
YHH3_k127_11379304_5 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 383.0
YHH3_k127_11379304_6 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 361.0
YHH3_k127_11379304_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 347.0
YHH3_k127_11379304_8 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 346.0
YHH3_k127_11379304_9 UbiE COQ5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 329.0
YHH3_k127_11465222_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 499.0
YHH3_k127_11465222_1 phenylalanine-tRNA ligase activity K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 501.0
YHH3_k127_11465222_10 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000006142 175.0
YHH3_k127_11465222_11 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000006443 167.0
YHH3_k127_11465222_12 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000000000000000000000007525 152.0
YHH3_k127_11465222_13 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000049 142.0
YHH3_k127_11465222_14 Family of unknown function (DUF438) K09155 - - 0.0000000000000000000000000002468 121.0
YHH3_k127_11465222_15 archaeal coiled-coil protein - - - 0.00000000000000000000000001379 120.0
YHH3_k127_11465222_16 Protein of unknown function (DUF1614) - - - 0.00000000000000003223 91.0
YHH3_k127_11465222_17 Transcriptional regulator, XRE family K03627 - - 0.0000000000000008895 83.0
YHH3_k127_11465222_18 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000009643 77.0
YHH3_k127_11465222_19 ABC-type uncharacterized transport system - - - 0.00000001038 69.0
YHH3_k127_11465222_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 485.0
YHH3_k127_11465222_21 metal-dependent phosphoesterases (PHP family) - - - 0.000002697 61.0
YHH3_k127_11465222_23 Peptidase M10 serralysin C terminal K01406 - 3.4.24.40 0.00006591 57.0
YHH3_k127_11465222_3 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 451.0
YHH3_k127_11465222_4 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 368.0
YHH3_k127_11465222_5 glutamine synthetase K01915 GO:0003674,GO:0005488,GO:0005515,GO:0006082,GO:0006355,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008134,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009605,GO:0009719,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016053,GO:0016597,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043392,GO:0043436,GO:0043562,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0045892,GO:0045934,GO:0046394,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0061984,GO:0065007,GO:0065009,GO:0070406,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:0090295,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1902679,GO:1903506,GO:1903507,GO:1904796,GO:1904797,GO:2000112,GO:2000113,GO:2000677,GO:2000678,GO:2001141 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 339.0
YHH3_k127_11465222_6 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 325.0
YHH3_k127_11465222_7 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003364 259.0
YHH3_k127_11465222_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000002014 198.0
YHH3_k127_11465222_9 Leucine rich repeats (6 copies) - - - 0.00000000000000000000000000000000000000000000000042 190.0
YHH3_k127_11527512_0 aconitate hydratase K01681 - 4.2.1.3 2.255e-290 903.0
YHH3_k127_11527512_1 TIGRFAM Acetate-CoA ligase K01895 - 6.2.1.1 2.435e-276 863.0
YHH3_k127_11527512_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 571.0
YHH3_k127_11527512_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002411 273.0
YHH3_k127_11527512_4 Papain family cysteine protease - - - 0.000000000000000000000000000000000001701 157.0
YHH3_k127_11527512_5 COG1522 Transcriptional regulators - - - 0.00000000000000000000000001572 123.0
YHH3_k127_11527512_6 protein kinase activity - - - 0.000001061 57.0
YHH3_k127_11527512_7 helix_turn_helix ASNC type K03719 - - 0.000006949 57.0
YHH3_k127_11539096_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 548.0
YHH3_k127_11539096_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 536.0
YHH3_k127_11539096_10 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 342.0
YHH3_k127_11539096_11 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 309.0
YHH3_k127_11539096_12 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 310.0
YHH3_k127_11539096_13 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 294.0
YHH3_k127_11539096_14 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 299.0
YHH3_k127_11539096_15 GHMP kinases C terminal K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000005352 262.0
YHH3_k127_11539096_16 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005404 261.0
YHH3_k127_11539096_17 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000001532 251.0
YHH3_k127_11539096_18 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
YHH3_k127_11539096_19 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000002466 231.0
YHH3_k127_11539096_2 P-type ATPase K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 544.0
YHH3_k127_11539096_20 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000002239 234.0
YHH3_k127_11539096_21 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000608 217.0
YHH3_k127_11539096_22 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000000000000000000000000000000000000000000000000307 203.0
YHH3_k127_11539096_23 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000002339 196.0
YHH3_k127_11539096_24 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000002428 191.0
YHH3_k127_11539096_25 methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000001511 192.0
YHH3_k127_11539096_26 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.00000000000000000000000000000000000000000000001331 183.0
YHH3_k127_11539096_27 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000002647 166.0
YHH3_k127_11539096_28 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000001979 170.0
YHH3_k127_11539096_29 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000001454 150.0
YHH3_k127_11539096_3 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 501.0
YHH3_k127_11539096_30 cell wall organization - - - 0.000000000000000000000000000001563 139.0
YHH3_k127_11539096_31 Transcriptional regulator, TrmB - - - 0.00000000000000000000000003285 112.0
YHH3_k127_11539096_32 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.00000000000000000000000008117 114.0
YHH3_k127_11539096_33 Fibronectin type III domain - - - 0.000000000000000000000008352 116.0
YHH3_k127_11539096_34 PQ loop repeat K15383 - - 0.000000000000000001421 87.0
YHH3_k127_11539096_35 Right handed beta helix region - - - 0.00000000000000001711 93.0
YHH3_k127_11539096_36 parallel beta-helix repeat K03671 - - 0.000000000000001183 89.0
YHH3_k127_11539096_37 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000002503 78.0
YHH3_k127_11539096_38 Nicotianamine synthase protein - - - 0.00000000000009899 80.0
YHH3_k127_11539096_39 - - - - 0.000000000006638 69.0
YHH3_k127_11539096_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 488.0
YHH3_k127_11539096_40 GDSL-like Lipase/Acylhydrolase family K02014 - - 0.0000000002766 72.0
YHH3_k127_11539096_41 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000001051 70.0
YHH3_k127_11539096_42 FeoA - - - 0.00000005361 62.0
YHH3_k127_11539096_43 secreted hydrolase - - - 0.0000002245 63.0
YHH3_k127_11539096_44 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.000007562 57.0
YHH3_k127_11539096_45 PFAM Glycosyl hydrolases family 38 C-terminal domain - - - 0.00003213 56.0
YHH3_k127_11539096_46 Lipocalin-like domain - - - 0.0005894 52.0
YHH3_k127_11539096_47 Peptidase family C25 - - - 0.0008403 53.0
YHH3_k127_11539096_5 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 478.0
YHH3_k127_11539096_6 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 464.0
YHH3_k127_11539096_7 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 453.0
YHH3_k127_11539096_8 resolution of meiotic recombination intermediates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 451.0
YHH3_k127_11539096_9 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 430.0
YHH3_k127_11845956_0 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 316.0
YHH3_k127_11845956_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000003133 233.0
YHH3_k127_11845956_2 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.00000000000000000000000000000000000000000000000000000001446 206.0
YHH3_k127_11845956_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000028 201.0
YHH3_k127_11845956_4 PFAM extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000001058 184.0
YHH3_k127_11845956_5 Predicted SAM-dependent RNA methyltransferase - - - 0.0000000000000000000000000000003652 130.0
YHH3_k127_12004282_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 8.038e-241 762.0
YHH3_k127_12093000_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 548.0
YHH3_k127_12093000_1 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002881 288.0
YHH3_k127_12093000_10 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000004063 70.0
YHH3_k127_12093000_11 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000002236 72.0
YHH3_k127_12093000_12 methyltransferase activity - - - 0.00000000001373 71.0
YHH3_k127_12093000_13 Tfp pilus assembly protein FimV - - - 0.00001192 52.0
YHH3_k127_12093000_14 SCP-2 sterol transfer family - - - 0.0004482 48.0
YHH3_k127_12093000_2 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000164 215.0
YHH3_k127_12093000_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000001789 215.0
YHH3_k127_12093000_4 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000000097 166.0
YHH3_k127_12093000_5 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000003967 113.0
YHH3_k127_12093000_6 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000002267 115.0
YHH3_k127_12093000_7 flavodoxin K00230 - 1.3.5.3 0.0000000000000000000001246 106.0
YHH3_k127_12093000_8 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000001151 83.0
YHH3_k127_12093000_9 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000002931 86.0
YHH3_k127_12160611_0 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000001038 124.0
YHH3_k127_12160611_1 PFAM Peptidase C1A, papain - - - 0.00000000000004993 86.0
YHH3_k127_12160611_2 PKD domain - - - 0.0000000000002896 80.0
YHH3_k127_12160611_3 - - - - 0.000000000001416 74.0
YHH3_k127_12160611_4 distant relative of cell wall-associated - - - 0.0000000526 64.0
YHH3_k127_12407688_0 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004824 273.0
YHH3_k127_12407688_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000004328 191.0
YHH3_k127_12407688_10 Transcriptional - - - 0.00008576 51.0
YHH3_k127_12407688_11 PFAM metallophosphoesterase - - - 0.0001349 53.0
YHH3_k127_12407688_12 membrane-associated protein domain - - - 0.000276 53.0
YHH3_k127_12407688_13 helix_turn_helix ASNC type - - - 0.0003508 50.0
YHH3_k127_12407688_14 Mo-molybdopterin cofactor metabolic process K03753 - - 0.0008326 44.0
YHH3_k127_12407688_15 Transcriptional - - - 0.0008902 49.0
YHH3_k127_12407688_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000002412 150.0
YHH3_k127_12407688_3 Papain family cysteine protease - - - 0.00000000000000000000000001357 126.0
YHH3_k127_12407688_4 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000001351 118.0
YHH3_k127_12407688_5 Domain of unknown function (DUF4382) - - - 0.0000000000000002356 85.0
YHH3_k127_12407688_6 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000004069 74.0
YHH3_k127_12407688_7 - - - - 0.00000000000009228 78.0
YHH3_k127_12407688_8 AAA C-terminal domain K07478 - - 0.00000005847 62.0
YHH3_k127_12407688_9 S-layer homology domain - - - 0.00003399 52.0
YHH3_k127_12498767_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 6.843e-241 784.0
YHH3_k127_12498767_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 470.0
YHH3_k127_12498767_10 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000000000113 186.0
YHH3_k127_12498767_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000747 175.0
YHH3_k127_12498767_12 SMART Excinuclease ABC, C subunit - - - 0.0000000000000000000000000000000000009906 143.0
YHH3_k127_12498767_13 PFAM Glycosyl transferase family 2 K21349 - 2.4.1.268 0.000000000000000000000000002479 113.0
YHH3_k127_12498767_14 hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000000006687 116.0
YHH3_k127_12498767_15 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000005308 105.0
YHH3_k127_12498767_16 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.000000000000000001521 89.0
YHH3_k127_12498767_17 Glycosyltransferase like family 2 K21349 - 2.4.1.268 0.00000000000000002025 83.0
YHH3_k127_12498767_18 4Fe-4S binding domain - - - 0.00000000000000003749 82.0
YHH3_k127_12498767_19 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.0000000000000002101 83.0
YHH3_k127_12498767_2 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 415.0
YHH3_k127_12498767_20 Glycosyltransferase like family 2 K21349 - 2.4.1.268 0.00000000000001109 77.0
YHH3_k127_12498767_21 transferase activity, transferring glycosyl groups K13693,K21349 - 2.4.1.266,2.4.1.268 0.00001349 47.0
YHH3_k127_12498767_22 transferase activity, transferring glycosyl groups K13693,K21349 - 2.4.1.266,2.4.1.268 0.0007844 42.0
YHH3_k127_12498767_3 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 386.0
YHH3_k127_12498767_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 360.0
YHH3_k127_12498767_5 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 318.0
YHH3_k127_12498767_6 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 302.0
YHH3_k127_12498767_7 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 294.0
YHH3_k127_12498767_8 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000001177 228.0
YHH3_k127_12498767_9 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000001183 210.0
YHH3_k127_12557298_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 449.0
YHH3_k127_12557298_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 418.0
YHH3_k127_12557298_10 PQQ-like domain - - - 0.00000000000000009636 94.0
YHH3_k127_12557298_11 chitinase K01183 - 3.2.1.14 0.00000000000002502 86.0
YHH3_k127_12557298_12 HEPN domain - - - 0.00000000001213 71.0
YHH3_k127_12557298_13 - - - - 0.00000000006702 68.0
YHH3_k127_12557298_14 - - - - 0.00000002463 58.0
YHH3_k127_12557298_15 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001279 65.0
YHH3_k127_12557298_16 Nucleotidyltransferase domain - - - 0.0000004548 59.0
YHH3_k127_12557298_17 ribosomal small subunit binding - - - 0.000004375 59.0
YHH3_k127_12557298_18 COG3209 Rhs family protein - - - 0.00001904 57.0
YHH3_k127_12557298_2 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 430.0
YHH3_k127_12557298_3 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 304.0
YHH3_k127_12557298_4 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001444 265.0
YHH3_k127_12557298_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000001396 207.0
YHH3_k127_12557298_6 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000001297 189.0
YHH3_k127_12557298_7 ribosomal protein S15 K02956 - - 0.0000000000000000000000000000000000000000000002628 171.0
YHH3_k127_12557298_8 Papain family cysteine protease - - - 0.000000000000000000000000003077 128.0
YHH3_k127_12557298_9 Fibronectin type III domain - - - 0.000000000000000002294 97.0
YHH3_k127_12666250_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 374.0
YHH3_k127_12666250_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 336.0
YHH3_k127_12666250_10 Family of unknown function (DUF5320) - - - 0.000000000000000000000007471 105.0
YHH3_k127_12666250_11 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000007926 79.0
YHH3_k127_12666250_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000002182 76.0
YHH3_k127_12666250_13 4Fe-4S binding domain K03616 - - 0.0000000000000256 74.0
YHH3_k127_12666250_14 Fe-S cluster K04488 - - 0.00000257 50.0
YHH3_k127_12666250_15 Protein of unknown function, DUF488 - - - 0.00006021 50.0
YHH3_k127_12666250_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 330.0
YHH3_k127_12666250_3 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009839 327.0
YHH3_k127_12666250_4 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.000000000000000000000000000000000000000000000000000000000000003797 222.0
YHH3_k127_12666250_5 beta-lactamase domain protein K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000001075 178.0
YHH3_k127_12666250_6 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.00000000000000000000000000000000000000005254 156.0
YHH3_k127_12666250_7 methyltransferase K15256 - - 0.00000000000000000000000000000000000004315 151.0
YHH3_k127_12666250_8 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000005805 134.0
YHH3_k127_12666250_9 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000001452 117.0
YHH3_k127_12759551_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 434.0
YHH3_k127_12759551_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002364 273.0
YHH3_k127_12759551_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000003089 250.0
YHH3_k127_12759551_3 Uncharacterised protein family UPF0066 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002122 244.0
YHH3_k127_12759551_4 Chlorophyllase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000157 241.0
YHH3_k127_12759551_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000004017 190.0
YHH3_k127_12759551_6 Belongs to the CinA family K03742 - 3.5.1.42 0.000000000000000000000000000000000000000009268 159.0
YHH3_k127_12759551_7 COG1321 Mn-dependent transcriptional regulator K03709 - - 0.0000000000000000000000000000000000001795 146.0
YHH3_k127_12759551_8 Rubrerythrin - - - 0.00000000000000000000000000000007155 126.0
YHH3_k127_12759551_9 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000001717 118.0
YHH3_k127_12805034_0 4-hydroxyphenylacetate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 614.0
YHH3_k127_12805034_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000002754 181.0
YHH3_k127_12805034_2 - - - - 0.000000000000000000000000000000000008751 143.0
YHH3_k127_1321920_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 467.0
YHH3_k127_1321920_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 336.0
YHH3_k127_1321920_10 TIGRFAM parallel beta-helix repeat (two copies) K07218 - - 0.000000000000003084 86.0
YHH3_k127_1321920_11 reductase - - - 0.00000000000002065 85.0
YHH3_k127_1321920_12 - - - - 0.00006473 53.0
YHH3_k127_1321920_2 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000001124 220.0
YHH3_k127_1321920_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000003106 221.0
YHH3_k127_1321920_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000001799 220.0
YHH3_k127_1321920_5 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000001232 214.0
YHH3_k127_1321920_6 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000003957 210.0
YHH3_k127_1321920_7 Protein of unknown function DUF86 K07075 - - 0.0000000000000000000000000000000000007617 141.0
YHH3_k127_1321920_8 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000002465 132.0
YHH3_k127_1321920_9 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000000005581 110.0
YHH3_k127_1380471_0 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000001666 132.0
YHH3_k127_1380471_1 His Kinase A (phosphoacceptor) domain - - - 0.0004174 52.0
YHH3_k127_1649512_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 449.0
YHH3_k127_1649512_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
YHH3_k127_1649512_10 Hexapeptide repeat of succinyl-transferase - - - 0.000000000007103 75.0
YHH3_k127_1649512_11 Transglutaminase/protease-like homologues - - - 0.00000001212 66.0
YHH3_k127_1649512_12 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.0000001729 57.0
YHH3_k127_1649512_13 - - - - 0.0000197 50.0
YHH3_k127_1649512_14 Transglutaminase-like superfamily - - - 0.00004719 55.0
YHH3_k127_1649512_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009751 258.0
YHH3_k127_1649512_3 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.00000000000000000000000000000000000000000000000003482 187.0
YHH3_k127_1649512_4 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000002697 169.0
YHH3_k127_1649512_5 Belongs to the PDCD5 family K06875 - - 0.00000000000000000005605 93.0
YHH3_k127_1649512_6 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001328 92.0
YHH3_k127_1649512_7 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.000000000000003895 84.0
YHH3_k127_1649512_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000005292 79.0
YHH3_k127_1649512_9 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000000004093 72.0
YHH3_k127_1654373_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 510.0
YHH3_k127_1654373_1 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 440.0
YHH3_k127_1654373_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 337.0
YHH3_k127_1654373_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000001992 168.0
YHH3_k127_1654373_4 - - - - 0.000000000000000002609 99.0
YHH3_k127_1770532_0 Heat shock 70 kDa protein K04043 - - 6.642e-240 756.0
YHH3_k127_1770532_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.008e-220 697.0
YHH3_k127_1770532_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000242 82.0
YHH3_k127_1770532_11 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000005328 73.0
YHH3_k127_1770532_12 Uncharacterised protein family (UPF0227) K07000 GO:0003674,GO:0003824,GO:0016787,GO:0016788 - 0.000001573 57.0
YHH3_k127_1770532_13 Belongs to the universal stress protein A family - - - 0.000003938 55.0
YHH3_k127_1770532_2 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 497.0
YHH3_k127_1770532_3 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 423.0
YHH3_k127_1770532_4 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000000000000225 213.0
YHH3_k127_1770532_5 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000009524 138.0
YHH3_k127_1770532_6 Pfam:DUF552 K09152 - - 0.00000000000000000000000001139 113.0
YHH3_k127_1770532_7 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000003071 91.0
YHH3_k127_1770532_8 PFAM CBS domain containing protein - - - 0.00000000000000001489 87.0
YHH3_k127_1770532_9 - - - - 0.0000000000000006732 85.0
YHH3_k127_1867258_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000008889 229.0
YHH3_k127_1867258_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000001015 62.0
YHH3_k127_1867666_0 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.0000000000008468 81.0
YHH3_k127_1867666_1 PFAM PKD domain containing protein - - - 0.000000000001409 81.0
YHH3_k127_1867666_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001347 53.0
YHH3_k127_1873751_0 E1-E2 ATPase K01533 - 3.6.3.4 1.333e-297 925.0
YHH3_k127_1873751_1 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.313e-294 930.0
YHH3_k127_1873751_10 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000004078 191.0
YHH3_k127_1873751_11 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000009753 172.0
YHH3_k127_1873751_12 Belongs to the UPF0178 family - - - 0.00000000000000000000000000000000000000000001901 164.0
YHH3_k127_1873751_13 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000002131 180.0
YHH3_k127_1873751_14 Zn_pept K05996 - 3.4.17.18 0.0000000000000000000000000000000000000001163 164.0
YHH3_k127_1873751_15 4 iron, 4 sulfur cluster binding K00196 - - 0.0000000000000000000000000000001888 131.0
YHH3_k127_1873751_16 serine threonine protein kinase - - - 0.000000000000000000000000000004747 128.0
YHH3_k127_1873751_17 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.000000000000000000000000009627 112.0
YHH3_k127_1873751_18 GPR1 FUN34 yaaH family protein K07034 - - 0.000000000000000000000000667 112.0
YHH3_k127_1873751_19 Short C-terminal domain K08982 - - 0.00000000000000000000001818 103.0
YHH3_k127_1873751_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.744e-274 865.0
YHH3_k127_1873751_20 - - - - 0.00000000000001763 79.0
YHH3_k127_1873751_21 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000002151 78.0
YHH3_k127_1873751_22 Periplasmic binding protein K02016 - - 0.000000000006571 74.0
YHH3_k127_1873751_24 Right handed beta helix region - - - 0.0000000007424 71.0
YHH3_k127_1873751_25 Major Facilitator Superfamily K08223 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944 - 0.000003271 59.0
YHH3_k127_1873751_26 SprT-like family K07043 - - 0.0003443 44.0
YHH3_k127_1873751_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 6.109e-205 657.0
YHH3_k127_1873751_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 512.0
YHH3_k127_1873751_5 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 505.0
YHH3_k127_1873751_6 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 418.0
YHH3_k127_1873751_7 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 369.0
YHH3_k127_1873751_8 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000006933 199.0
YHH3_k127_1873751_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000001073 194.0
YHH3_k127_2306977_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 419.0
YHH3_k127_2306977_1 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008208 271.0
YHH3_k127_2306977_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000004408 230.0
YHH3_k127_2306977_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000001514 188.0
YHH3_k127_2306977_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000001282 174.0
YHH3_k127_2306977_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000001544 136.0
YHH3_k127_2315838_0 Transposase - - - 0.00000000002669 65.0
YHH3_k127_2315838_2 TOPRIM K17680 - 3.6.4.12 0.0000553 57.0
YHH3_k127_239343_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 3.248e-242 761.0
YHH3_k127_239343_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.933e-220 691.0
YHH3_k127_239343_10 CAAX protease self-immunity K07052 - - 0.0003238 51.0
YHH3_k127_239343_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000002132 201.0
YHH3_k127_239343_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000001569 193.0
YHH3_k127_239343_4 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000001019 196.0
YHH3_k127_239343_5 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000000006459 123.0
YHH3_k127_239343_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000665 111.0
YHH3_k127_239343_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000004802 97.0
YHH3_k127_239343_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.0000000000001456 75.0
YHH3_k127_239343_9 subunit K K02124 - - 0.000000000001138 70.0
YHH3_k127_2592634_0 Peptidase family C25 - - - 0.00000007401 64.0
YHH3_k127_2592634_1 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.0001371 52.0
YHH3_k127_2592872_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 520.0
YHH3_k127_2592872_1 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 445.0
YHH3_k127_2592872_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000007108 150.0
YHH3_k127_2592872_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000699 142.0
YHH3_k127_2592872_4 Protein of unknown function (DUF504) K09715 - - 0.0000000005444 63.0
YHH3_k127_2592872_5 Propeptide_C25 - - - 0.000006811 58.0
YHH3_k127_2758271_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 462.0
YHH3_k127_2758271_1 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 430.0
YHH3_k127_2758271_10 - - - - 0.000000000000004313 78.0
YHH3_k127_2758271_11 COG2335 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.00000000001836 68.0
YHH3_k127_2758271_12 collagenase K01387 - 3.4.24.3 0.00000002111 65.0
YHH3_k127_2758271_13 bacterial-type flagellum-dependent cell motility - - - 0.0000001432 59.0
YHH3_k127_2758271_14 recA bacterial DNA recombination protein K10872,K19347 GO:0000003,GO:0000150,GO:0000166,GO:0000217,GO:0000228,GO:0000280,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0000781,GO:0000793,GO:0000794,GO:0001541,GO:0001556,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007129,GO:0007131,GO:0007140,GO:0007141,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007292,GO:0007548,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008406,GO:0008585,GO:0009314,GO:0009628,GO:0009987,GO:0009994,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019953,GO:0021700,GO:0022402,GO:0022412,GO:0022414,GO:0022607,GO:0030154,GO:0030554,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034622,GO:0034641,GO:0035639,GO:0035825,GO:0036094,GO:0042148,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045003,GO:0045132,GO:0045137,GO:0045143,GO:0046483,GO:0046545,GO:0046660,GO:0048232,GO:0048285,GO:0048468,GO:0048469,GO:0048477,GO:0048513,GO:0048515,GO:0048599,GO:0048608,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050896,GO:0051276,GO:0051321,GO:0051704,GO:0051716,GO:0061458,GO:0061982,GO:0065003,GO:0065004,GO:0070013,GO:0070192,GO:0071695,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0097367,GO:0098687,GO:0098813,GO:0140013,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1903046 - 0.0002112 52.0
YHH3_k127_2758271_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006043 258.0
YHH3_k127_2758271_3 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005847 258.0
YHH3_k127_2758271_4 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000002146 222.0
YHH3_k127_2758271_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000001809 186.0
YHH3_k127_2758271_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000003615 179.0
YHH3_k127_2758271_7 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000006447 171.0
YHH3_k127_2758271_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000008356 157.0
YHH3_k127_2758271_9 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000002057 110.0
YHH3_k127_2796244_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 480.0
YHH3_k127_2796244_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 353.0
YHH3_k127_2796244_10 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000175 231.0
YHH3_k127_2796244_11 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000008115 220.0
YHH3_k127_2796244_12 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.0000000000000000000000000000000000000000000000007157 195.0
YHH3_k127_2796244_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000001896 149.0
YHH3_k127_2796244_14 Uncharacterised protein family (UPF0179) K09730 - - 0.000000000000000000000000000000000006939 141.0
YHH3_k127_2796244_15 Papain family cysteine protease - - - 0.0000000000000000000000000000000001602 147.0
YHH3_k127_2796244_16 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000001376 118.0
YHH3_k127_2796244_17 - - - - 0.00000000000000000000000002955 112.0
YHH3_k127_2796244_18 membrane - - - 0.000000000000000000000003383 116.0
YHH3_k127_2796244_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07646 - 2.7.13.3 0.000000000000000004944 98.0
YHH3_k127_2796244_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 331.0
YHH3_k127_2796244_20 Lipoate-protein ligase a K03800 - 6.3.1.20 0.00000001708 61.0
YHH3_k127_2796244_21 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0002863 53.0
YHH3_k127_2796244_22 UbiA prenyltransferase family - - - 0.0008666 51.0
YHH3_k127_2796244_3 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 343.0
YHH3_k127_2796244_4 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 326.0
YHH3_k127_2796244_5 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 297.0
YHH3_k127_2796244_6 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 293.0
YHH3_k127_2796244_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000001079 262.0
YHH3_k127_2796244_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000354 257.0
YHH3_k127_2796244_9 Peptidase S9 prolyl oligopeptidase active site K01281 - 3.4.14.11 0.00000000000000000000000000000000000000000000000000000000000000000000001502 253.0
YHH3_k127_2799653_0 KH, type 1, domain K07041 - - 8.381e-261 817.0
YHH3_k127_2799653_1 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 455.0
YHH3_k127_2799653_10 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000001984 196.0
YHH3_k127_2799653_11 cyclohydrolase K01746 - 4.3.1.4 0.00000000000000000000000000000000000000000000000008005 185.0
YHH3_k127_2799653_12 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000003081 114.0
YHH3_k127_2799653_13 PRC-barrel domain - - - 0.00000000000001656 77.0
YHH3_k127_2799653_14 - - - - 0.000006353 50.0
YHH3_k127_2799653_15 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00001897 49.0
YHH3_k127_2799653_16 Response regulator, receiver K07677,K07679,K20974 - 2.7.13.3 0.0003504 43.0
YHH3_k127_2799653_2 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 431.0
YHH3_k127_2799653_3 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 366.0
YHH3_k127_2799653_4 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 332.0
YHH3_k127_2799653_5 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 317.0
YHH3_k127_2799653_6 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001915 292.0
YHH3_k127_2799653_7 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003265 267.0
YHH3_k127_2799653_8 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000005326 239.0
YHH3_k127_2799653_9 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000005325 201.0
YHH3_k127_285098_0 flavodoxin nitric oxide synthase - - - 1.346e-197 621.0
YHH3_k127_285098_1 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 462.0
YHH3_k127_285098_10 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000001446 181.0
YHH3_k127_285098_11 Predicted permease - - - 0.0000000000000000000000000000000000000000000000005432 179.0
YHH3_k127_285098_12 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000005754 178.0
YHH3_k127_285098_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000001994 173.0
YHH3_k127_285098_14 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000002156 169.0
YHH3_k127_285098_15 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000002613 172.0
YHH3_k127_285098_16 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000008531 168.0
YHH3_k127_285098_17 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000000372 146.0
YHH3_k127_285098_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000002701 148.0
YHH3_k127_285098_19 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000001144 129.0
YHH3_k127_285098_2 COG1131 ABC-type multidrug transport system ATPase component K16907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 360.0
YHH3_k127_285098_20 TIGRFAM MIP family channel K02440,K06188 - - 0.00000000000000000000000000000004586 127.0
YHH3_k127_285098_21 - K16905,K16906 - - 0.000000000000000000000000005413 119.0
YHH3_k127_285098_22 Winged helix-turn-helix - - - 0.00000000000000000000000000558 112.0
YHH3_k127_285098_23 transmembrane transport K01992 - - 0.00000000000000000000000002977 117.0
YHH3_k127_285098_24 6-phosphogluconolactonase activity - - - 0.000000000000000000001928 110.0
YHH3_k127_285098_26 Protein of unknown function (DUF3795) - - - 0.00000000000001051 79.0
YHH3_k127_285098_27 - - - - 0.0000000000005976 77.0
YHH3_k127_285098_28 Major intrinsic protein K06188 - - 0.0000000000009318 70.0
YHH3_k127_285098_29 Fibronectin type III domain protein - - - 0.000000000001319 79.0
YHH3_k127_285098_3 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 314.0
YHH3_k127_285098_30 cysteine-type endopeptidase activity K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.000000000007644 79.0
YHH3_k127_285098_31 PKD domain K19668 - 3.2.1.91 0.0000000001028 75.0
YHH3_k127_285098_32 Flavodoxin domain - - - 0.000001346 56.0
YHH3_k127_285098_33 2TM domain - - - 0.000009598 49.0
YHH3_k127_285098_34 Subtilase family - - - 0.0000382 58.0
YHH3_k127_285098_35 - - - - 0.00008782 48.0
YHH3_k127_285098_4 transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 301.0
YHH3_k127_285098_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
YHH3_k127_285098_6 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000002393 207.0
YHH3_k127_285098_7 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000414 207.0
YHH3_k127_285098_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000565 205.0
YHH3_k127_285098_9 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000004365 201.0
YHH3_k127_3189387_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0002161,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.623e-204 668.0
YHH3_k127_3189387_1 tRNA binding K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 495.0
YHH3_k127_3189387_11 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.0000001862 54.0
YHH3_k127_3189387_13 - - - - 0.000000499 52.0
YHH3_k127_3189387_14 but it may be involved in stabilization of the trimeric complex - - - 0.0000006355 52.0
YHH3_k127_3189387_15 COG1522 Transcriptional regulators - - - 0.00009995 51.0
YHH3_k127_3189387_16 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0001173 54.0
YHH3_k127_3189387_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 431.0
YHH3_k127_3189387_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 391.0
YHH3_k127_3189387_4 MiaB-like tRNA modifying enzyme, archaeal-type K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 347.0
YHH3_k127_3189387_5 Helix-turn-helix XRE-family like proteins K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000005058 230.0
YHH3_k127_3189387_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000006028 198.0
YHH3_k127_3503258_0 CBS domain K03498 - - 0.00000000000000000000000000000000000000000000000000001356 208.0
YHH3_k127_3503258_1 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000002882 170.0
YHH3_k127_3503258_2 C-terminal domain of CHU protein family - - - 0.000000000369 72.0
YHH3_k127_3503258_3 membrane-associated protein domain - - - 0.00000001396 68.0
YHH3_k127_3503258_4 PKD domain containing protein - - - 0.00000104 62.0
YHH3_k127_4168376_0 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 243.0
YHH3_k127_4168376_1 PFAM Integrase, catalytic core - - - 0.00000000000002015 84.0
YHH3_k127_4168376_2 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000001756 53.0
YHH3_k127_4168376_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000001816 53.0
YHH3_k127_4316366_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1450.0
YHH3_k127_4316366_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.304e-300 932.0
YHH3_k127_4316366_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 615.0
YHH3_k127_4316366_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 337.0
YHH3_k127_4316366_4 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006214 266.0
YHH3_k127_4316366_5 membrane K09790 - - 0.0000000000000000000000000000000002025 136.0
YHH3_k127_4316366_6 Domain present in carbohydrate binding proteins and sugar hydrolses - - - 0.000000006529 63.0
YHH3_k127_4370516_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 591.0
YHH3_k127_4370516_1 aminopeptidase K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 427.0
YHH3_k127_4370516_10 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000000008835 106.0
YHH3_k127_4370516_11 Papain family cysteine protease - - - 0.000000000000000000000001021 120.0
YHH3_k127_4370516_12 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.00000000000000000002591 104.0
YHH3_k127_4370516_13 cell wall organization - - - 0.000000000000003867 88.0
YHH3_k127_4370516_14 Propeptide_C25 - - - 0.00000000000009916 85.0
YHH3_k127_4370516_15 Propeptide_C25 - - - 0.000000000002331 80.0
YHH3_k127_4370516_16 Sugar (and other) transporter K08196,K08369 - - 0.000000000006382 78.0
YHH3_k127_4370516_17 Transposase - - - 0.00000000003669 65.0
YHH3_k127_4370516_18 PFAM TPR repeat-containing protein - - - 0.00000000003783 76.0
YHH3_k127_4370516_19 Right handed beta helix region - - - 0.00000000007438 75.0
YHH3_k127_4370516_2 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006625 421.0
YHH3_k127_4370516_20 glucose sorbosone - - - 0.0000000001644 75.0
YHH3_k127_4370516_21 Lrp/AsnC ligand binding domain - - - 0.0000003943 54.0
YHH3_k127_4370516_22 Domain of unknown function (DU1801) - - - 0.000005543 54.0
YHH3_k127_4370516_3 transferase activity, transferring glycosyl groups K01179,K01356,K13735,K21449 - 3.2.1.4,3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 367.0
YHH3_k127_4370516_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 328.0
YHH3_k127_4370516_5 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000002329 173.0
YHH3_k127_4370516_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000001352 134.0
YHH3_k127_4370516_7 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.000000000000000000000000000000007503 136.0
YHH3_k127_4370516_8 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000001126 129.0
YHH3_k127_4370516_9 Acyl-protein synthetase, LuxE - - - 0.000000000000000000000000000002036 136.0
YHH3_k127_4422652_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 3.981e-210 668.0
YHH3_k127_4422652_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 3.176e-208 669.0
YHH3_k127_4422652_10 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000001661 236.0
YHH3_k127_4422652_11 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000006126 229.0
YHH3_k127_4422652_12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000002725 200.0
YHH3_k127_4422652_13 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000003167 201.0
YHH3_k127_4422652_14 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000522 196.0
YHH3_k127_4422652_15 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) - - - 0.0000000000000000000000000000000000000000000007431 169.0
YHH3_k127_4422652_16 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.000000000000000000000000000000000000000001112 162.0
YHH3_k127_4422652_17 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000003264 154.0
YHH3_k127_4422652_18 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000001083 149.0
YHH3_k127_4422652_19 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000009591 144.0
YHH3_k127_4422652_2 DEAD DEAH box helicase domain protein K10896 - - 1.802e-201 651.0
YHH3_k127_4422652_20 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000001317 99.0
YHH3_k127_4422652_21 cell adhesion involved in biofilm formation K02014,K11031 - - 0.0000000000000000000001425 113.0
YHH3_k127_4422652_22 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000433 98.0
YHH3_k127_4422652_23 Domain present in carbohydrate binding proteins and sugar hydrolses - - - 0.00000000000000000006078 102.0
YHH3_k127_4422652_24 RNA polymerase K03051 - 2.7.7.6 0.0000000000000001907 83.0
YHH3_k127_4422652_25 Belongs to the V-ATPase proteolipid subunit family K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 - 0.00000000000001609 79.0
YHH3_k127_4422652_26 PKD domain - - - 0.0000000000001055 83.0
YHH3_k127_4422652_27 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000003827 70.0
YHH3_k127_4422652_28 Double zinc ribbon - - - 0.000000000006308 70.0
YHH3_k127_4422652_29 Small multi-drug export protein - - - 0.0000000001456 70.0
YHH3_k127_4422652_3 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 497.0
YHH3_k127_4422652_30 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000001579 68.0
YHH3_k127_4422652_31 helix_turn_helix ASNC type - - - 0.0003293 49.0
YHH3_k127_4422652_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 455.0
YHH3_k127_4422652_5 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 331.0
YHH3_k127_4422652_6 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 327.0
YHH3_k127_4422652_7 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 313.0
YHH3_k127_4422652_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000001152 268.0
YHH3_k127_4422652_9 Belongs to the complex I 20 kDa subunit family K18023 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000009901 238.0
YHH3_k127_4472223_0 - - - - 0.0000000000000000000103 96.0
YHH3_k127_4472223_1 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000000000000006548 95.0
YHH3_k127_4472223_2 Di-glucose binding within endoplasmic reticulum - - - 0.000001973 53.0
YHH3_k127_4472223_3 Caspase domain - - - 0.000004622 58.0
YHH3_k127_4472223_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002892 54.0
YHH3_k127_4673739_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1609.0
YHH3_k127_4673739_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 4.725e-216 683.0
YHH3_k127_4673739_10 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 362.0
YHH3_k127_4673739_11 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 366.0
YHH3_k127_4673739_12 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 365.0
YHH3_k127_4673739_13 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 345.0
YHH3_k127_4673739_14 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001086 246.0
YHH3_k127_4673739_15 Met-10+ like-protein K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000001185 242.0
YHH3_k127_4673739_16 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003647 226.0
YHH3_k127_4673739_17 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000001165 213.0
YHH3_k127_4673739_18 domain protein K03698 - - 0.0000000000000000000000000000000000000000000000000000000003631 216.0
YHH3_k127_4673739_19 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000000000000000001645 195.0
YHH3_k127_4673739_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 591.0
YHH3_k127_4673739_20 ATP-AMP transphosphorylase K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000003245 190.0
YHH3_k127_4673739_21 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000000002574 178.0
YHH3_k127_4673739_22 phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000001998 171.0
YHH3_k127_4673739_23 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000519 157.0
YHH3_k127_4673739_24 Type II secretion system K07333 - - 0.000000000000000000000000000000000000103 153.0
YHH3_k127_4673739_25 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000005444 142.0
YHH3_k127_4673739_26 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000003383 137.0
YHH3_k127_4673739_27 Type II secretion system K07333 - - 0.00000000000000000000000000000001959 137.0
YHH3_k127_4673739_28 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000005967 132.0
YHH3_k127_4673739_29 metal-dependent phosphoesterases (PHP family) - - - 0.0000000000000000000000000000755 124.0
YHH3_k127_4673739_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 562.0
YHH3_k127_4673739_30 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000207 114.0
YHH3_k127_4673739_31 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.0000000000000000000000001535 115.0
YHH3_k127_4673739_32 Belongs to the UPF0273 family - - - 0.00000000000000000000002792 109.0
YHH3_k127_4673739_33 Predicted membrane protein (DUF2085) - - - 0.00000000000000000000003065 106.0
YHH3_k127_4673739_34 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000008478 102.0
YHH3_k127_4673739_35 Integral membrane protein DUF106 - - - 0.0000000000000000000001027 106.0
YHH3_k127_4673739_36 - K00960 - 2.7.7.6 0.000000000000000002918 85.0
YHH3_k127_4673739_37 Trm112p-like protein - - - 0.000000000000000004143 85.0
YHH3_k127_4673739_38 PFAM PKD domain containing protein - - - 0.0000000000000001675 90.0
YHH3_k127_4673739_39 - - - - 0.0000000000000004758 79.0
YHH3_k127_4673739_4 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 537.0
YHH3_k127_4673739_40 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000001881 66.0
YHH3_k127_4673739_41 - - - - 0.0000000000307 72.0
YHH3_k127_4673739_42 cell wall organization K01448 - 3.5.1.28 0.0000000305 68.0
YHH3_k127_4673739_43 PKD domain containing protein - - - 0.00000132 56.0
YHH3_k127_4673739_44 LamG domain protein jellyroll fold domain protein - - - 0.00004325 57.0
YHH3_k127_4673739_45 - - - - 0.00008544 47.0
YHH3_k127_4673739_46 Domain of unknown function (DUF2341) - - - 0.0001564 55.0
YHH3_k127_4673739_47 protein conserved in archaea - - - 0.0003978 48.0
YHH3_k127_4673739_5 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 480.0
YHH3_k127_4673739_6 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 465.0
YHH3_k127_4673739_7 Type II/IV secretion system protein K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 452.0
YHH3_k127_4673739_8 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 370.0
YHH3_k127_4673739_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 371.0
YHH3_k127_4679833_0 FAD binding domain K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 5.482e-223 703.0
YHH3_k127_4679833_1 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 531.0
YHH3_k127_4679833_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
YHH3_k127_4679833_11 ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004349 264.0
YHH3_k127_4679833_12 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000001535 213.0
YHH3_k127_4679833_13 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000252 142.0
YHH3_k127_4679833_14 Protein of unknown function (DUF1667) - - - 0.00000000000000000000000000000009138 127.0
YHH3_k127_4679833_15 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000000000000002128 104.0
YHH3_k127_4679833_16 COG1522 Transcriptional regulators - - - 0.000000000000000000001157 107.0
YHH3_k127_4679833_17 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000001278 83.0
YHH3_k127_4679833_18 Dodecin K09165 - - 0.000006976 50.0
YHH3_k127_4679833_2 Aldehyde dehydrogenase family K00135,K08324 GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006520,GO:0006525,GO:0006527,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009060,GO:0009063,GO:0009064,GO:0009065,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009448,GO:0009450,GO:0009987,GO:0015980,GO:0016020,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044464,GO:0045333,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0072329,GO:0072350,GO:0097164,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.24,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 511.0
YHH3_k127_4679833_3 ferredoxin oxidoreductase, subunit alpha K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 427.0
YHH3_k127_4679833_4 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 428.0
YHH3_k127_4679833_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 408.0
YHH3_k127_4679833_6 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 372.0
YHH3_k127_4679833_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 358.0
YHH3_k127_4679833_8 Fumarate hydratase K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 344.0
YHH3_k127_4679833_9 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 335.0
YHH3_k127_4685583_0 Flavin containing amine oxidoreductase K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 526.0
YHH3_k127_4685583_1 UV-endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 354.0
YHH3_k127_4685583_2 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 338.0
YHH3_k127_4685583_3 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 336.0
YHH3_k127_4685583_4 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000001763 105.0
YHH3_k127_4685583_5 PFAM DNA photolyase K01669 - 4.1.99.3 0.00000000001016 66.0
YHH3_k127_4786122_0 COG0058 Glucan phosphorylase - - - 7.803e-218 691.0
YHH3_k127_4786122_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 491.0
YHH3_k127_4786122_10 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 436.0
YHH3_k127_4786122_11 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 425.0
YHH3_k127_4786122_12 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 431.0
YHH3_k127_4786122_13 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 419.0
YHH3_k127_4786122_14 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 365.0
YHH3_k127_4786122_15 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 365.0
YHH3_k127_4786122_16 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 353.0
YHH3_k127_4786122_17 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 353.0
YHH3_k127_4786122_18 TIGRFAM ribosomal RNA small subunit methyltransferase RsmB K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 351.0
YHH3_k127_4786122_19 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 334.0
YHH3_k127_4786122_2 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 462.0
YHH3_k127_4786122_20 Clp protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 339.0
YHH3_k127_4786122_21 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 332.0
YHH3_k127_4786122_22 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 322.0
YHH3_k127_4786122_23 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 310.0
YHH3_k127_4786122_24 Starch synthase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 312.0
YHH3_k127_4786122_25 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 306.0
YHH3_k127_4786122_26 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 307.0
YHH3_k127_4786122_27 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 295.0
YHH3_k127_4786122_28 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 293.0
YHH3_k127_4786122_29 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 298.0
YHH3_k127_4786122_3 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 464.0
YHH3_k127_4786122_30 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 295.0
YHH3_k127_4786122_31 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 289.0
YHH3_k127_4786122_32 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001752 271.0
YHH3_k127_4786122_33 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003927 271.0
YHH3_k127_4786122_34 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
YHH3_k127_4786122_35 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007118 271.0
YHH3_k127_4786122_36 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001214 258.0
YHH3_k127_4786122_37 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000001079 262.0
YHH3_k127_4786122_38 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 257.0
YHH3_k127_4786122_39 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000659 255.0
YHH3_k127_4786122_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 469.0
YHH3_k127_4786122_40 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000005268 248.0
YHH3_k127_4786122_41 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000001721 237.0
YHH3_k127_4786122_42 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000009347 228.0
YHH3_k127_4786122_43 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002897 225.0
YHH3_k127_4786122_44 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000002098 231.0
YHH3_k127_4786122_45 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000001778 225.0
YHH3_k127_4786122_46 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000001963 213.0
YHH3_k127_4786122_47 Na H ion antiporter subunit K05569 - - 0.00000000000000000000000000000000000000000000000000000000008845 208.0
YHH3_k127_4786122_48 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000001401 203.0
YHH3_k127_4786122_49 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000001163 201.0
YHH3_k127_4786122_5 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 460.0
YHH3_k127_4786122_50 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.00000000000000000000000000000000000000000000000000003085 194.0
YHH3_k127_4786122_51 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000749 186.0
YHH3_k127_4786122_52 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000001161 197.0
YHH3_k127_4786122_53 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000001129 173.0
YHH3_k127_4786122_54 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000002587 171.0
YHH3_k127_4786122_55 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000003925 161.0
YHH3_k127_4786122_56 transcription regulator activity - - - 0.00000000000000000000000000000000000000002131 157.0
YHH3_k127_4786122_57 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.0000000000000000000000000000000000000448 151.0
YHH3_k127_4786122_58 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.0000000000000000000000000000000000001118 147.0
YHH3_k127_4786122_59 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000001685 150.0
YHH3_k127_4786122_6 TIGRFAM glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 467.0
YHH3_k127_4786122_60 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000000000003593 136.0
YHH3_k127_4786122_61 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000007399 137.0
YHH3_k127_4786122_62 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000004574 133.0
YHH3_k127_4786122_63 Na+/H+ antiporter subunit K05571 - - 0.00000000000000000000000000000001196 130.0
YHH3_k127_4786122_64 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000194 130.0
YHH3_k127_4786122_65 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000002664 124.0
YHH3_k127_4786122_66 - - - - 0.00000000000000000000000001171 113.0
YHH3_k127_4786122_67 PFAM multiple resistance and pH regulation protein F K05570 - - 0.0000000000000000000003955 98.0
YHH3_k127_4786122_68 PFAM glutaredoxin - - - 0.0000000000000000000007112 97.0
YHH3_k127_4786122_69 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000102 103.0
YHH3_k127_4786122_7 NADH-Ubiquinone plastoquinone (complex I) K05568,K14115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 461.0
YHH3_k127_4786122_70 PFAM peptidase - - - 0.00000000000000000003509 105.0
YHH3_k127_4786122_71 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000396 92.0
YHH3_k127_4786122_72 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000004431 94.0
YHH3_k127_4786122_73 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000001712 99.0
YHH3_k127_4786122_74 Membrane bound hydrogenase - - - 0.00000000000000001063 86.0
YHH3_k127_4786122_75 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000002336 79.0
YHH3_k127_4786122_76 PFAM regulatory protein, ArsR - - - 0.0000000000000002465 88.0
YHH3_k127_4786122_77 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000001004 86.0
YHH3_k127_4786122_78 cluster protein-associated redox disulfide domain - - - 0.000000000000003262 78.0
YHH3_k127_4786122_79 Transcriptional regulator K07108 - - 0.00000000000001479 78.0
YHH3_k127_4786122_8 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 452.0
YHH3_k127_4786122_80 PFAM Peptidase C1A, papain - - - 0.00000000000001584 87.0
YHH3_k127_4786122_81 Uncharacterised protein - - - 0.00000000000001902 87.0
YHH3_k127_4786122_82 Domain of unknown function (DUF4040) - - - 0.0000000000001075 74.0
YHH3_k127_4786122_83 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000001678 72.0
YHH3_k127_4786122_84 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000002035 70.0
YHH3_k127_4786122_85 PFAM CobN Magnesium Chelatase - - - 0.000000003741 70.0
YHH3_k127_4786122_86 transcription regulator activity - - - 0.00000005216 64.0
YHH3_k127_4786122_87 PRC-barrel domain - - - 0.000001378 53.0
YHH3_k127_4786122_88 transcriptional regulator K05800 - - 0.00007398 52.0
YHH3_k127_4786122_89 acid phosphatase activity - - - 0.00009672 55.0
YHH3_k127_4786122_9 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 455.0
YHH3_k127_4786122_90 AsnC-type helix-turn-helix domain K03718 - - 0.0001529 53.0
YHH3_k127_4786122_91 - - - - 0.0002033 46.0
YHH3_k127_4790073_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 371.0
YHH3_k127_4790073_1 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003497 272.0
YHH3_k127_4790073_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.0000000000000000004198 89.0
YHH3_k127_4790073_11 PFAM regulatory protein, ArsR K03892,K21903 - - 0.00000000000001334 76.0
YHH3_k127_4790073_13 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000004006 72.0
YHH3_k127_4790073_2 Abc transporter K02035 - - 0.0000000000000000000000000000000000000000000000000000000001851 222.0
YHH3_k127_4790073_3 peroxiredoxin activity - - - 0.000000000000000000000000000000000000000000000566 167.0
YHH3_k127_4790073_4 DGC domain - - - 0.000000000000000000000000000000000004064 140.0
YHH3_k127_4790073_5 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000004808 139.0
YHH3_k127_4790073_6 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000005759 134.0
YHH3_k127_4790073_7 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000003043 115.0
YHH3_k127_4790073_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000001538 115.0
YHH3_k127_4790073_9 redox-active disulfide protein 2 - - - 0.0000000000000000000003924 98.0
YHH3_k127_4806574_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 481.0
YHH3_k127_4806574_1 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 372.0
YHH3_k127_4806574_10 SMART Cystathionine beta-synthase, core - - - 0.00000000000000000000000004096 117.0
YHH3_k127_4806574_11 - - - - 0.000000000000000000001048 100.0
YHH3_k127_4806574_12 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.000000000000000000001735 98.0
YHH3_k127_4806574_13 Thiamine-binding protein - - - 0.000000000000000002097 88.0
YHH3_k127_4806574_14 AMP binding - - - 0.0000000000000006955 83.0
YHH3_k127_4806574_15 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000006474 80.0
YHH3_k127_4806574_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 334.0
YHH3_k127_4806574_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 324.0
YHH3_k127_4806574_4 Integral membrane sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000008688 213.0
YHH3_k127_4806574_5 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000002967 177.0
YHH3_k127_4806574_6 Archaeal holliday junction resolvase (hjc) - - - 0.0000000000000000000000000000000000000000000001725 173.0
YHH3_k127_4806574_7 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000002419 142.0
YHH3_k127_4806574_8 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.0000000000000000000000000000000001123 144.0
YHH3_k127_4806574_9 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000002561 116.0
YHH3_k127_4847059_0 - - - - 0.000000000000000000000000000000000005044 144.0
YHH3_k127_4847059_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000000002911 126.0
YHH3_k127_4847059_2 Domain of unknown function (DUF4382) - - - 0.000000000000000004034 91.0
YHH3_k127_4847059_3 - - - - 0.000000001377 66.0
YHH3_k127_4847059_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000005004 62.0
YHH3_k127_4847059_5 transcriptional regulator K03719 - - 0.000001036 57.0
YHH3_k127_487792_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 9.502e-194 617.0
YHH3_k127_487792_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 594.0
YHH3_k127_487792_10 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000001012 119.0
YHH3_k127_487792_11 amine dehydrogenase activity - - - 0.000000000000000159 92.0
YHH3_k127_487792_12 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000003233 65.0
YHH3_k127_487792_13 - - - - 0.000000002229 65.0
YHH3_k127_487792_14 Winged helix-turn-helix domain (DUF2582) - - - 0.0000002574 57.0
YHH3_k127_487792_15 Winged helix-turn-helix domain (DUF2582) - - - 0.0000005968 56.0
YHH3_k127_487792_16 Winged helix-turn-helix domain (DUF2582) - - - 0.000001114 55.0
YHH3_k127_487792_17 Winged helix-turn-helix domain (DUF2582) - - - 0.000001671 55.0
YHH3_k127_487792_2 PFAM type II secretion system protein E K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 544.0
YHH3_k127_487792_3 PFAM type II secretion system protein E K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 503.0
YHH3_k127_487792_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 434.0
YHH3_k127_487792_5 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 404.0
YHH3_k127_487792_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000002365 228.0
YHH3_k127_487792_7 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000001854 184.0
YHH3_k127_487792_8 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000001094 171.0
YHH3_k127_487792_9 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000001042 173.0
YHH3_k127_5023412_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 391.0
YHH3_k127_5023412_1 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 391.0
YHH3_k127_5023412_10 - - - - 0.0000000000000000000000286 101.0
YHH3_k127_5023412_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000007532 89.0
YHH3_k127_5023412_12 Peptidase m28 - - - 0.000000000000000002 98.0
YHH3_k127_5023412_13 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000003672 83.0
YHH3_k127_5023412_14 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000002157 60.0
YHH3_k127_5023412_15 Transcriptional regulator - - - 0.000003709 57.0
YHH3_k127_5023412_16 PFAM Periplasmic copper-binding protein (NosD) K07218 - - 0.000003906 58.0
YHH3_k127_5023412_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 375.0
YHH3_k127_5023412_3 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008699 260.0
YHH3_k127_5023412_4 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002151 238.0
YHH3_k127_5023412_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000001755 226.0
YHH3_k127_5023412_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000001919 221.0
YHH3_k127_5023412_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000001015 165.0
YHH3_k127_5023412_8 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000001107 169.0
YHH3_k127_5023412_9 response regulator, receiver K07668,K07669 - - 0.000000000000000000000007394 106.0
YHH3_k127_5058425_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 577.0
YHH3_k127_5058425_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000004603 243.0
YHH3_k127_5058425_2 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000001904 226.0
YHH3_k127_5058425_3 snoRNA binding domain, fibrillarin K14564 - - 0.000000000000000000000000000000000000000000001351 176.0
YHH3_k127_5058425_4 protein conserved in archaea - - - 0.000000000000000002437 90.0
YHH3_k127_5058425_5 Phage integrase family - - - 0.000007459 53.0
YHH3_k127_5058925_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 7.416e-245 776.0
YHH3_k127_5058925_1 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 2.677e-217 687.0
YHH3_k127_5058925_10 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 304.0
YHH3_k127_5058925_11 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 306.0
YHH3_k127_5058925_12 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 304.0
YHH3_k127_5058925_13 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001395 290.0
YHH3_k127_5058925_14 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000856 284.0
YHH3_k127_5058925_15 Conserved hypothetical ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000001069 244.0
YHH3_k127_5058925_16 Rad51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005433 242.0
YHH3_k127_5058925_17 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000003146 245.0
YHH3_k127_5058925_18 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001429 225.0
YHH3_k127_5058925_19 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000001554 224.0
YHH3_k127_5058925_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 440.0
YHH3_k127_5058925_20 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000203 221.0
YHH3_k127_5058925_21 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.00000000000000000000000000000000000000000000000000000000008516 214.0
YHH3_k127_5058925_22 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000399 172.0
YHH3_k127_5058925_23 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000738 160.0
YHH3_k127_5058925_24 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000001444 168.0
YHH3_k127_5058925_25 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000005819 149.0
YHH3_k127_5058925_26 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000158 141.0
YHH3_k127_5058925_27 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000005499 139.0
YHH3_k127_5058925_28 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000554 125.0
YHH3_k127_5058925_29 cysteine-type endopeptidase activity K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.000000000000000000674 102.0
YHH3_k127_5058925_3 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 441.0
YHH3_k127_5058925_30 PFAM Peptidase C1A, papain - - - 0.000000000000000000702 102.0
YHH3_k127_5058925_31 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000111 87.0
YHH3_k127_5058925_32 Transcriptional regulator - - - 0.000000000000000001842 94.0
YHH3_k127_5058925_33 glucose sorbosone - - - 0.00000000000000001131 96.0
YHH3_k127_5058925_34 - - - - 0.00000000000000003649 82.0
YHH3_k127_5058925_35 lactoylglutathione lyase activity - - - 0.00000000000000007252 85.0
YHH3_k127_5058925_36 Protein of unknown function (DUF1349) - - - 0.000000000000004823 89.0
YHH3_k127_5058925_37 - - - - 0.000000000000008413 81.0
YHH3_k127_5058925_38 protein conserved in archaea - - - 0.00000000007039 74.0
YHH3_k127_5058925_39 Circadian clock protein KaiC - - - 0.0000000001183 71.0
YHH3_k127_5058925_4 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 409.0
YHH3_k127_5058925_40 periplasmic copper-binding protein NosD K07218 - - 0.0000000006981 71.0
YHH3_k127_5058925_41 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000065 68.0
YHH3_k127_5058925_42 FR47-like protein K03789 - 2.3.1.128 0.000000008055 63.0
YHH3_k127_5058925_43 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000008123 69.0
YHH3_k127_5058925_44 Uncharacterised protein family UPF0058 - - - 0.0000001262 57.0
YHH3_k127_5058925_45 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00001443 54.0
YHH3_k127_5058925_5 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 415.0
YHH3_k127_5058925_6 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 370.0
YHH3_k127_5058925_7 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 357.0
YHH3_k127_5058925_8 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 334.0
YHH3_k127_5058925_9 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 302.0
YHH3_k127_5077848_0 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000000001576 197.0
YHH3_k127_5077848_1 glucosylceramidase activity - - - 0.000000000000000000000000000003194 123.0
YHH3_k127_5077848_2 HEAT repeats K03301 - - 0.000000000000000000000000009625 124.0
YHH3_k127_5077848_3 of the cupin superfamily K06995 - - 0.00000000000000000000006779 100.0
YHH3_k127_5077848_4 Transposase IS200 like K07491 - - 0.0000000000003006 76.0
YHH3_k127_5077848_5 cell wall organization - - - 0.0000000003663 72.0
YHH3_k127_5077848_6 alginic acid biosynthetic process - - - 0.0000001532 64.0
YHH3_k127_5077848_7 helix_turn_helix ASNC type K03718 - - 0.0008628 49.0
YHH3_k127_5317311_0 Protein of unknown function (DUF996) - - - 0.0000000000000000000000000000000000003455 148.0
YHH3_k127_549254_0 Belongs to the RtcB family K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 563.0
YHH3_k127_549254_1 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 481.0
YHH3_k127_549254_2 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 477.0
YHH3_k127_549254_3 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 411.0
YHH3_k127_549254_4 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 317.0
YHH3_k127_549254_5 Phosphopantothenate/pantothenate synthetase K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002863 274.0
YHH3_k127_549254_6 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000003369 219.0
YHH3_k127_549254_7 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000003603 170.0
YHH3_k127_5855731_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 536.0
YHH3_k127_5855731_1 coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 458.0
YHH3_k127_5855731_10 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000003055 188.0
YHH3_k127_5855731_11 S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 K15450 - 2.1.1.282 0.00000000000000000000000000000000000000000008265 167.0
YHH3_k127_5855731_12 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000002197 164.0
YHH3_k127_5855731_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000199 156.0
YHH3_k127_5855731_14 - - - - 0.0000000000000000000000000000000001011 154.0
YHH3_k127_5855731_15 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000002005 128.0
YHH3_k127_5855731_16 - - - - 0.0000000000000000000000000000006757 138.0
YHH3_k127_5855731_17 - - - - 0.0000000000000000000009104 109.0
YHH3_k127_5855731_18 Spi protease inhibitor - - - 0.00000000000000001568 97.0
YHH3_k127_5855731_19 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.00000000000001374 88.0
YHH3_k127_5855731_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 371.0
YHH3_k127_5855731_20 transposase K07497 - - 0.0000000001581 64.0
YHH3_k127_5855731_21 aminopeptidase activity - - - 0.00000002419 66.0
YHH3_k127_5855731_22 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000003291 67.0
YHH3_k127_5855731_23 cellulase activity - - - 0.000001599 62.0
YHH3_k127_5855731_24 - - - - 0.000006082 55.0
YHH3_k127_5855731_3 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 355.0
YHH3_k127_5855731_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 357.0
YHH3_k127_5855731_5 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 329.0
YHH3_k127_5855731_6 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 312.0
YHH3_k127_5855731_7 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003958 288.0
YHH3_k127_5855731_8 Peptidase family C25 - - - 0.0000000000000000000000000000000000000000000000000000000000000001186 250.0
YHH3_k127_5855731_9 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000005795 214.0
YHH3_k127_5960191_0 ATP-citrate synthase K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 1.59e-251 789.0
YHH3_k127_5960191_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 620.0
YHH3_k127_5960191_2 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 555.0
YHH3_k127_5960191_3 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 312.0
YHH3_k127_5960191_4 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004954 287.0
YHH3_k127_5960191_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000003924 168.0
YHH3_k127_5960191_6 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000007592 125.0
YHH3_k127_5960191_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000001124 123.0
YHH3_k127_5960191_8 PKD domain - - - 0.00000000000013 84.0
YHH3_k127_6001917_0 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002513 253.0
YHH3_k127_6001917_1 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000000000000000000104 162.0
YHH3_k127_6001917_2 Lysine exporter protein LysE YggA - - - 0.00000000000000000000000000000000000002516 151.0
YHH3_k127_6001917_3 membrane-associated protein domain - - - 0.00000000175 70.0
YHH3_k127_6001917_4 AsnC family transcriptional regulator K03719 - - 0.000139 52.0
YHH3_k127_6001917_5 Double zinc ribbon - - - 0.0008554 47.0
YHH3_k127_61335_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008501 300.0
YHH3_k127_61335_1 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002316 301.0
YHH3_k127_61335_2 PFAM PKD domain containing protein - - - 0.00000000001653 78.0
YHH3_k127_61335_3 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000001683 65.0
YHH3_k127_624858_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 580.0
YHH3_k127_624858_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000032 278.0
YHH3_k127_624858_10 integrase family K04763 - - 0.000005797 56.0
YHH3_k127_624858_11 - - - - 0.00001025 51.0
YHH3_k127_624858_12 Phage integrase family - - - 0.0001371 52.0
YHH3_k127_624858_13 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0003443 53.0
YHH3_k127_624858_14 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0003644 52.0
YHH3_k127_624858_2 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases K20616 - - 0.00000000000000000000000000000000000000000000000000000008101 205.0
YHH3_k127_624858_3 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000006895 195.0
YHH3_k127_624858_4 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000003966 173.0
YHH3_k127_624858_5 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000001158 160.0
YHH3_k127_624858_6 Peptidase family M28 - - - 0.0000000000000000000000000000001679 141.0
YHH3_k127_624858_7 Fibronectin type III domain - - - 0.000000000000000000000000000005162 136.0
YHH3_k127_624858_8 PFAM PEGA domain - - - 0.00000000000002484 85.0
YHH3_k127_624858_9 PFAM periplasmic copper-binding - - - 0.00000001476 65.0
YHH3_k127_6282328_0 - K03561,K12287 - - 0.00000000000000000000000000000000000001737 166.0
YHH3_k127_6282328_1 Pfam:DUF1628 - - - 0.00000000000001328 87.0
YHH3_k127_6282328_2 amine dehydrogenase activity - - - 0.00002197 50.0
YHH3_k127_6282328_3 PFAM Fibronectin type III domain - - - 0.0007948 53.0
YHH3_k127_6488033_0 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 548.0
YHH3_k127_6488033_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 475.0
YHH3_k127_6488033_2 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.000000000001378 72.0
YHH3_k127_653395_0 PFAM Glycosyl transferase, group 1 - - - 2.028e-289 906.0
YHH3_k127_653395_1 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 5.822e-237 745.0
YHH3_k127_653395_10 4Fe-4S ferredoxin iron-sulfur binding domain protein K00390,K14108 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000005847 201.0
YHH3_k127_653395_11 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000002805 190.0
YHH3_k127_653395_12 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000001379 152.0
YHH3_k127_653395_13 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000007717 146.0
YHH3_k127_653395_14 methyltransferase activity - - - 0.000000000000000000000006729 107.0
YHH3_k127_653395_15 Transcriptional regulator, TrmB - - - 0.000000000000000000001492 98.0
YHH3_k127_653395_16 - - - - 0.000000000000000000007533 101.0
YHH3_k127_653395_17 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000000000000004768 101.0
YHH3_k127_653395_18 Phage integrase family - - - 0.00000000000000001649 88.0
YHH3_k127_653395_19 exopeptidase activity - - - 0.00000000000000002508 95.0
YHH3_k127_653395_2 beta-1,4-mannooligosaccharide phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 511.0
YHH3_k127_653395_20 PFAM Ig domain protein group 2 domain protein - - - 0.0000000000000000942 96.0
YHH3_k127_653395_21 Peptidase family C25 - - - 0.000000000008723 78.0
YHH3_k127_653395_22 Kelch motif - - - 0.000000003054 70.0
YHH3_k127_653395_23 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000002354 57.0
YHH3_k127_653395_24 secreted hydrolase - - - 0.00000005375 65.0
YHH3_k127_653395_25 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000004554 64.0
YHH3_k127_653395_26 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001473 62.0
YHH3_k127_653395_27 - - - - 0.00001303 50.0
YHH3_k127_653395_29 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0001543 52.0
YHH3_k127_653395_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 483.0
YHH3_k127_653395_30 chitin catabolic process K01179,K03933,K11904 - 3.2.1.4 0.0001673 54.0
YHH3_k127_653395_31 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000194 46.0
YHH3_k127_653395_4 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 345.0
YHH3_k127_653395_5 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 308.0
YHH3_k127_653395_6 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002217 285.0
YHH3_k127_653395_7 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000009282 266.0
YHH3_k127_653395_8 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000006716 254.0
YHH3_k127_653395_9 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000004348 239.0
YHH3_k127_6557081_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 5.11e-217 690.0
YHH3_k127_6557081_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 395.0
YHH3_k127_6557081_2 ATP-grasp enzyme K17810 - 6.3.1.12 0.0000000000000000000000000000000000000000000000000000008826 207.0
YHH3_k127_6557081_3 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000008625 184.0
YHH3_k127_6557081_4 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000009979 162.0
YHH3_k127_6557081_5 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.00000004122 63.0
YHH3_k127_6599800_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1150.0
YHH3_k127_6599800_1 helicase superfamily c-terminal domain K03724 - - 1.045e-260 833.0
YHH3_k127_6599800_10 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 481.0
YHH3_k127_6599800_11 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 470.0
YHH3_k127_6599800_12 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 466.0
YHH3_k127_6599800_13 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
YHH3_k127_6599800_14 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 375.0
YHH3_k127_6599800_15 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 363.0
YHH3_k127_6599800_16 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008321 350.0
YHH3_k127_6599800_17 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 336.0
YHH3_k127_6599800_18 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 304.0
YHH3_k127_6599800_19 GTP-binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 294.0
YHH3_k127_6599800_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 1.117e-258 830.0
YHH3_k127_6599800_20 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 296.0
YHH3_k127_6599800_21 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001034 280.0
YHH3_k127_6599800_22 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000002351 251.0
YHH3_k127_6599800_23 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000006226 242.0
YHH3_k127_6599800_24 Asparaginase, N-terminal K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000001962 224.0
YHH3_k127_6599800_25 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000002056 203.0
YHH3_k127_6599800_26 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001863 196.0
YHH3_k127_6599800_27 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000002768 187.0
YHH3_k127_6599800_28 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000002632 181.0
YHH3_k127_6599800_29 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000002148 160.0
YHH3_k127_6599800_3 FMN binding - - - 8.431e-246 767.0
YHH3_k127_6599800_30 reverse transcriptase - - - 0.000000000000000000000000000000000647 136.0
YHH3_k127_6599800_31 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000002417 135.0
YHH3_k127_6599800_32 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000001886 133.0
YHH3_k127_6599800_33 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000004576 117.0
YHH3_k127_6599800_34 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000002444 106.0
YHH3_k127_6599800_35 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000003776 103.0
YHH3_k127_6599800_36 TOPRIM - - - 0.0000000000000000001559 94.0
YHH3_k127_6599800_37 Cold-Shock Protein K03704 - - 0.00000000000000001105 84.0
YHH3_k127_6599800_39 Zn-ribbon containing protein K07163 - - 0.00000000000000003919 88.0
YHH3_k127_6599800_4 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 4.623e-219 686.0
YHH3_k127_6599800_40 Protease prsW family - - - 0.000000000000001256 87.0
YHH3_k127_6599800_41 Belongs to the UPF0235 family K09131 - - 0.00000000000001262 81.0
YHH3_k127_6599800_42 - - - - 0.000000000009004 76.0
YHH3_k127_6599800_44 - - - - 0.000000000666 63.0
YHH3_k127_6599800_45 acid phosphatase activity K22390 - - 0.000000002311 71.0
YHH3_k127_6599800_46 Pkd domain containing protein - - - 0.00000001168 66.0
YHH3_k127_6599800_47 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000526 64.0
YHH3_k127_6599800_48 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.000001308 59.0
YHH3_k127_6599800_49 Group II intron, maturase-specific domain - - - 0.00001857 47.0
YHH3_k127_6599800_5 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.791e-218 697.0
YHH3_k127_6599800_50 Transposase IS200 like K07491 - - 0.0002378 45.0
YHH3_k127_6599800_51 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0002688 44.0
YHH3_k127_6599800_52 - - - - 0.000695 46.0
YHH3_k127_6599800_6 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005302 616.0
YHH3_k127_6599800_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 607.0
YHH3_k127_6599800_8 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 557.0
YHH3_k127_6599800_9 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 475.0
YHH3_k127_6956423_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 527.0
YHH3_k127_6956423_1 TIGRFAM TraB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007407 289.0
YHH3_k127_6956423_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002181 261.0
YHH3_k127_6956423_3 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002693 191.0
YHH3_k127_6956423_4 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000964 171.0
YHH3_k127_6956423_5 Peptidase M50 - - - 0.0000000000000000000000000000000001039 143.0
YHH3_k127_6956423_6 - - - - 0.0000000000000000000000000003534 123.0
YHH3_k127_6956423_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000033 82.0
YHH3_k127_6992720_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000316 154.0
YHH3_k127_6992720_1 transcriptional - - - 0.0000000000000005864 80.0
YHH3_k127_6992720_2 PFAM NHL repeat containing protein - - - 0.000000001186 68.0
YHH3_k127_6992720_3 helix_turn_helix ASNC type K03719 - - 0.0006407 49.0
YHH3_k127_7054238_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 411.0
YHH3_k127_7054238_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 341.0
YHH3_k127_7054238_2 Dihydroorotate dehydrogenase K02823 - - 0.000000000000000000000000000000000000000000000000000000000000005963 225.0
YHH3_k127_7054238_3 Helix-turn-helix K07108 - - 0.0000000000000005805 81.0
YHH3_k127_7054238_4 - - - - 0.0002104 51.0
YHH3_k127_7183017_0 agmatine deiminase activity K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 536.0
YHH3_k127_7183017_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 492.0
YHH3_k127_7183017_10 PFAM UvrD REP helicase - - - 0.000006308 52.0
YHH3_k127_7183017_2 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 403.0
YHH3_k127_7183017_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 357.0
YHH3_k127_7183017_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 327.0
YHH3_k127_7183017_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000797 237.0
YHH3_k127_7183017_6 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000001347 199.0
YHH3_k127_7183017_7 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000001015 102.0
YHH3_k127_7183017_8 Domain of unknown function (DUF4314) - - - 0.00000002586 57.0
YHH3_k127_7183017_9 - - - - 0.00000142 52.0
YHH3_k127_718978_0 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002402 250.0
YHH3_k127_718978_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000001825 230.0
YHH3_k127_718978_2 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000001114 144.0
YHH3_k127_718978_3 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000002179 145.0
YHH3_k127_718978_4 Peptidase S8 K08651 - 3.4.21.66 0.00000000000000000000000000002463 128.0
YHH3_k127_718978_5 COG3420 Nitrous oxidase accessory protein K07218 - - 0.000000000000000000000003731 119.0
YHH3_k127_718978_6 Pregnancy-associated plasma protein-A - - - 0.000000000000001578 91.0
YHH3_k127_718978_7 - - - - 0.0000000000002749 73.0
YHH3_k127_718978_8 DNA polymerase K02320 - 2.7.7.7 0.00006547 57.0
YHH3_k127_7227023_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1123.0
YHH3_k127_7227023_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.055e-287 911.0
YHH3_k127_7227023_10 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 386.0
YHH3_k127_7227023_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 346.0
YHH3_k127_7227023_12 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 351.0
YHH3_k127_7227023_13 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 314.0
YHH3_k127_7227023_14 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 300.0
YHH3_k127_7227023_15 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 297.0
YHH3_k127_7227023_16 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008263 279.0
YHH3_k127_7227023_17 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001055 275.0
YHH3_k127_7227023_18 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
YHH3_k127_7227023_19 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007469 254.0
YHH3_k127_7227023_2 Cell division protein 48 (CDC48) N-terminal domain K13525 - - 3.185e-276 873.0
YHH3_k127_7227023_20 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006735 256.0
YHH3_k127_7227023_21 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000004159 243.0
YHH3_k127_7227023_22 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000003361 227.0
YHH3_k127_7227023_23 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000004468 233.0
YHH3_k127_7227023_24 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000001336 218.0
YHH3_k127_7227023_25 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000007854 213.0
YHH3_k127_7227023_26 Acyl-CoA reductase (LuxC) - - - 0.00000000000000000000000000000000000000000000000000000002915 215.0
YHH3_k127_7227023_27 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000005688 209.0
YHH3_k127_7227023_28 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.0000000000000000000000000000000000000000000000000000009822 197.0
YHH3_k127_7227023_29 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000001063 202.0
YHH3_k127_7227023_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 7.013e-276 870.0
YHH3_k127_7227023_30 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000002109 183.0
YHH3_k127_7227023_31 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000003407 178.0
YHH3_k127_7227023_32 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000001223 171.0
YHH3_k127_7227023_33 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000002037 177.0
YHH3_k127_7227023_34 Acyl-protein synthetase, LuxE - - - 0.00000000000000000000000000000000000000001212 170.0
YHH3_k127_7227023_35 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000042 135.0
YHH3_k127_7227023_36 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.00000000000000000000000000000000137 133.0
YHH3_k127_7227023_37 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000007512 131.0
YHH3_k127_7227023_38 Putative small multi-drug export protein - - - 0.00000000000000000000000000000007895 130.0
YHH3_k127_7227023_39 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000001291 113.0
YHH3_k127_7227023_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 599.0
YHH3_k127_7227023_40 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000004404 105.0
YHH3_k127_7227023_41 phosphorelay signal transduction system K07658 - - 0.0000000000000000000004438 101.0
YHH3_k127_7227023_42 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000001136 85.0
YHH3_k127_7227023_43 PRC-barrel domain - - - 0.000000000000001389 79.0
YHH3_k127_7227023_44 FR47-like protein K03789 - 2.3.1.128 0.00000000000002199 79.0
YHH3_k127_7227023_45 Major facilitator Superfamily K08162,K08226,K16211 - - 0.0000000000001987 82.0
YHH3_k127_7227023_46 cell adhesion involved in biofilm formation - - - 0.000000000001083 80.0
YHH3_k127_7227023_47 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.000000000003848 73.0
YHH3_k127_7227023_48 Sterol carrier protein - - - 0.00000000001629 70.0
YHH3_k127_7227023_49 Electron transfer flavoprotein K03522 - - 0.0000000004122 62.0
YHH3_k127_7227023_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 608.0
YHH3_k127_7227023_50 - - - - 0.000000001273 65.0
YHH3_k127_7227023_51 protein conserved in archaea - - - 0.000000002371 66.0
YHH3_k127_7227023_52 Bacterial PH domain - - - 0.00000001263 66.0
YHH3_k127_7227023_53 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000001342 55.0
YHH3_k127_7227023_54 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000008869 58.0
YHH3_k127_7227023_55 - - - - 0.00001842 54.0
YHH3_k127_7227023_56 COG1522 Transcriptional regulators - - - 0.00002137 56.0
YHH3_k127_7227023_57 In the absence or at low concentrations of lysine, activates the biosynthesis of this amino acid via the alpha- aminoadipate (AAA) pathway K06154 - - 0.0000501 55.0
YHH3_k127_7227023_58 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0002339 51.0
YHH3_k127_7227023_59 Pfam:DUF217 - - - 0.0005067 45.0
YHH3_k127_7227023_6 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 464.0
YHH3_k127_7227023_60 SpoVT / AbrB like domain - - - 0.0005285 46.0
YHH3_k127_7227023_7 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 405.0
YHH3_k127_7227023_8 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 362.0
YHH3_k127_7227023_9 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 363.0
YHH3_k127_7426411_0 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 481.0
YHH3_k127_7426411_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002731 292.0
YHH3_k127_7426411_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
YHH3_k127_7426411_3 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000503 231.0
YHH3_k127_7426411_4 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000001907 183.0
YHH3_k127_7426411_5 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000003917 116.0
YHH3_k127_7426411_6 Fibronectin type III domain - - - 0.0000000000000000000000003234 120.0
YHH3_k127_7426411_7 - - - - 0.00000000000000000002538 100.0
YHH3_k127_7426411_8 response regulator, receiver - - - 0.000000000000002104 90.0
YHH3_k127_7514479_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 3.851e-265 827.0
YHH3_k127_7514479_1 Threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008452 411.0
YHH3_k127_7514479_10 Belongs to the peptidase C1 family K01275 GO:0000323,GO:0001775,GO:0001906,GO:0001909,GO:0001913,GO:0002250,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002449,GO:0002456,GO:0002460,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005793,GO:0005794,GO:0005798,GO:0005813,GO:0005815,GO:0005856,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006915,GO:0006955,GO:0006996,GO:0007568,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008236,GO:0009056,GO:0009057,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010952,GO:0012501,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016485,GO:0016504,GO:0016505,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0019899,GO:0019902,GO:0022607,GO:0023051,GO:0023056,GO:0030134,GO:0030135,GO:0030141,GO:0030162,GO:0030163,GO:0030234,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031404,GO:0031410,GO:0031638,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032502,GO:0032940,GO:0033116,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042176,GO:0042221,GO:0042582,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043621,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045732,GO:0045862,GO:0046903,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051087,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0051604,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0052547,GO:0060205,GO:0060255,GO:0061024,GO:0061134,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090114,GO:0097708,GO:0098588,GO:0098772,GO:0099503,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:2001233,GO:2001235 3.4.14.1 0.00000000000000000000000000000000002008 153.0
YHH3_k127_7514479_11 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000002162 149.0
YHH3_k127_7514479_12 Collagenase - - - 0.000000000000000000000000008924 124.0
YHH3_k127_7514479_13 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000000000985 104.0
YHH3_k127_7514479_15 Domain of unknown function (DUF4870) - - - 0.0000000000000000000005569 99.0
YHH3_k127_7514479_16 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX - - - 0.00000000000000000009183 102.0
YHH3_k127_7514479_17 - - - - 0.000000000000000003948 85.0
YHH3_k127_7514479_18 PFAM zinc finger SWIM domain protein - - - 0.00000000000000005714 94.0
YHH3_k127_7514479_19 - - - - 0.0000000000007238 78.0
YHH3_k127_7514479_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 410.0
YHH3_k127_7514479_20 COG3291 FOG PKD repeat - - - 0.000000000001533 80.0
YHH3_k127_7514479_21 - - - - 0.00000000103 61.0
YHH3_k127_7514479_22 Peptidase family C25 - - - 0.000000001943 71.0
YHH3_k127_7514479_23 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000003136 70.0
YHH3_k127_7514479_24 Probable zinc-ribbon domain - - - 0.000002124 57.0
YHH3_k127_7514479_25 - - - - 0.0000095 55.0
YHH3_k127_7514479_26 EamA-like transporter family - - - 0.000273 52.0
YHH3_k127_7514479_27 Leucine-rich repeat (LRR) protein K01337 - 3.4.21.50 0.0004547 51.0
YHH3_k127_7514479_3 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 366.0
YHH3_k127_7514479_4 helicase superfamily c-terminal domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 372.0
YHH3_k127_7514479_5 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000005119 243.0
YHH3_k127_7514479_6 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000003585 233.0
YHH3_k127_7514479_7 Methyl-transferase - - - 0.000000000000000000000000000000000000000007501 167.0
YHH3_k127_7514479_8 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000002233 173.0
YHH3_k127_7514479_9 diguanylate cyclase activity - - - 0.000000000000000000000000000000000005066 143.0
YHH3_k127_7530134_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 6.535e-241 760.0
YHH3_k127_7530134_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 605.0
YHH3_k127_7530134_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000004952 189.0
YHH3_k127_7530134_3 PFAM Peptidase C1A, papain - - - 0.000000000000000000000000001371 129.0
YHH3_k127_7530134_4 Hsp20/alpha crystallin family K13993 - - 0.000000000000002446 84.0
YHH3_k127_7530134_5 PFAM Nitroreductase - - - 0.00000000000002283 85.0
YHH3_k127_7530134_6 Endonuclease I - - - 0.000000000007158 78.0
YHH3_k127_7530134_7 PFAM Nitroreductase - - - 0.000001623 60.0
YHH3_k127_7584052_0 Iron-containing alcohol dehydrogenase K19955 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 453.0
YHH3_k127_7584052_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 288.0
YHH3_k127_7584052_2 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000001187 232.0
YHH3_k127_7584052_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000003495 199.0
YHH3_k127_7584052_4 - - - - 0.0000000000000000000000000002849 128.0
YHH3_k127_7584052_5 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000001369 123.0
YHH3_k127_7584052_6 metallocarboxypeptidase activity - - - 0.0000000001659 74.0
YHH3_k127_7584052_7 - - - - 0.00002902 50.0
YHH3_k127_7584052_8 PFAM CBS domain containing protein K07182 - - 0.0007648 49.0
YHH3_k127_7728040_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1170.0
YHH3_k127_7728040_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 - 2.7.7.6 0.0 1167.0
YHH3_k127_7728040_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004456 272.0
YHH3_k127_7728040_11 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
YHH3_k127_7728040_12 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001014 246.0
YHH3_k127_7728040_13 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000003457 221.0
YHH3_k127_7728040_14 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000006681 226.0
YHH3_k127_7728040_15 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000004922 213.0
YHH3_k127_7728040_16 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000001442 211.0
YHH3_k127_7728040_17 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000002267 150.0
YHH3_k127_7728040_18 4Fe-4S binding domain - - - 0.0000000000000000000000000000000009043 136.0
YHH3_k127_7728040_19 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.000000000000000000000000000003221 124.0
YHH3_k127_7728040_2 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.309e-210 673.0
YHH3_k127_7728040_20 Participates in transcription termination K02600 - - 0.0000000000000000000000000006997 120.0
YHH3_k127_7728040_21 binds to the 23S rRNA K02921 - - 0.0000000000000000000000005376 107.0
YHH3_k127_7728040_22 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000001271 99.0
YHH3_k127_7728040_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000002511 96.0
YHH3_k127_7728040_24 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.00000000000000000005235 92.0
YHH3_k127_7728040_25 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000001305 86.0
YHH3_k127_7728040_26 PFAM PKD domain containing protein - - - 0.0000000000002642 81.0
YHH3_k127_7728040_27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000002394 56.0
YHH3_k127_7728040_28 Transcription factor Pcc1 K09741 - - 0.0000001406 57.0
YHH3_k127_7728040_29 DNA replication initiation - - - 0.0007219 46.0
YHH3_k127_7728040_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 527.0
YHH3_k127_7728040_4 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 482.0
YHH3_k127_7728040_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 476.0
YHH3_k127_7728040_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 407.0
YHH3_k127_7728040_7 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 341.0
YHH3_k127_7728040_8 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 312.0
YHH3_k127_7728040_9 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 301.0
YHH3_k127_7979084_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1592.0
YHH3_k127_7979084_1 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 3.576e-269 857.0
YHH3_k127_7979084_10 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 438.0
YHH3_k127_7979084_11 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 426.0
YHH3_k127_7979084_12 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 412.0
YHH3_k127_7979084_13 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 400.0
YHH3_k127_7979084_14 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 387.0
YHH3_k127_7979084_15 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 397.0
YHH3_k127_7979084_16 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 368.0
YHH3_k127_7979084_17 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 361.0
YHH3_k127_7979084_18 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 357.0
YHH3_k127_7979084_19 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 348.0
YHH3_k127_7979084_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.017e-219 700.0
YHH3_k127_7979084_20 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 336.0
YHH3_k127_7979084_21 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 328.0
YHH3_k127_7979084_22 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 304.0
YHH3_k127_7979084_23 ABC-type phosphate transport system, periplasmic component K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 293.0
YHH3_k127_7979084_24 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 288.0
YHH3_k127_7979084_25 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002568 287.0
YHH3_k127_7979084_26 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 274.0
YHH3_k127_7979084_27 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001321 268.0
YHH3_k127_7979084_28 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005214 267.0
YHH3_k127_7979084_29 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000644 262.0
YHH3_k127_7979084_3 Asparaginase K01424 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 4.196e-215 676.0
YHH3_k127_7979084_30 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001092 266.0
YHH3_k127_7979084_31 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005478 256.0
YHH3_k127_7979084_32 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003528 256.0
YHH3_k127_7979084_33 HhH-GPD family K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000002104 244.0
YHH3_k127_7979084_34 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000001639 244.0
YHH3_k127_7979084_35 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000005559 236.0
YHH3_k127_7979084_36 BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000000000000000000004322 234.0
YHH3_k127_7979084_37 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000004864 232.0
YHH3_k127_7979084_38 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
YHH3_k127_7979084_39 PFAM Histone deacetylase K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000001716 238.0
YHH3_k127_7979084_4 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 7.861e-196 621.0
YHH3_k127_7979084_40 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000004564 218.0
YHH3_k127_7979084_41 - - - - 0.0000000000000000000000000000000000000000000000000000000001205 213.0
YHH3_k127_7979084_42 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004433 203.0
YHH3_k127_7979084_43 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000008154 191.0
YHH3_k127_7979084_44 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000004757 183.0
YHH3_k127_7979084_45 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004889 187.0
YHH3_k127_7979084_46 Purple acid Phosphatase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000008362 195.0
YHH3_k127_7979084_47 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000001877 187.0
YHH3_k127_7979084_48 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000002511 183.0
YHH3_k127_7979084_49 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000002403 173.0
YHH3_k127_7979084_5 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 486.0
YHH3_k127_7979084_50 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.0000000000000000000000000000000000000000000002468 183.0
YHH3_k127_7979084_51 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000405 168.0
YHH3_k127_7979084_52 PFAM NMD3 family K07562 - - 0.00000000000000000000000000000000000000000001271 175.0
YHH3_k127_7979084_53 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000002571 166.0
YHH3_k127_7979084_54 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000003416 166.0
YHH3_k127_7979084_55 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000002731 162.0
YHH3_k127_7979084_56 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000004229 170.0
YHH3_k127_7979084_57 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000003017 168.0
YHH3_k127_7979084_58 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000008964 159.0
YHH3_k127_7979084_59 Thioredoxin K03671 - - 0.000000000000000000000000000000000000006641 149.0
YHH3_k127_7979084_6 GatB/GatE catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 492.0
YHH3_k127_7979084_60 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000007302 145.0
YHH3_k127_7979084_61 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000006548 143.0
YHH3_k127_7979084_62 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000001315 141.0
YHH3_k127_7979084_63 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002463 141.0
YHH3_k127_7979084_64 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000001417 140.0
YHH3_k127_7979084_65 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000302 143.0
YHH3_k127_7979084_66 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000006256 147.0
YHH3_k127_7979084_67 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000003197 125.0
YHH3_k127_7979084_68 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000004951 129.0
YHH3_k127_7979084_69 COG0681 Signal peptidase I K13280 - 3.4.21.89 0.0000000000000000000000000002973 124.0
YHH3_k127_7979084_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 479.0
YHH3_k127_7979084_70 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000003058 130.0
YHH3_k127_7979084_71 ribosomal protein L24 K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000003061 117.0
YHH3_k127_7979084_72 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.000000000000000000000002617 117.0
YHH3_k127_7979084_73 peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000009209 103.0
YHH3_k127_7979084_74 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000004702 90.0
YHH3_k127_7979084_75 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000005825 93.0
YHH3_k127_7979084_76 ribosomal protein S14 K02954 - - 0.00000000000000002066 82.0
YHH3_k127_7979084_77 Ribosomal L29 protein K02904 - - 0.00000000000000002124 83.0
YHH3_k127_7979084_78 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000017 80.0
YHH3_k127_7979084_79 protein conserved in archaea K09723 - - 0.0000000000000635 79.0
YHH3_k127_7979084_8 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 458.0
YHH3_k127_7979084_80 amine dehydrogenase activity - - - 0.0000000000002741 82.0
YHH3_k127_7979084_81 - - - - 0.000000000001435 77.0
YHH3_k127_7979084_82 COG2002 Regulators of stationary sporulation gene expression - - - 0.0000000004807 61.0
YHH3_k127_7979084_83 Winged helix-turn-helix domain (DUF2582) - - - 0.000000002046 64.0
YHH3_k127_7979084_84 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000004474 59.0
YHH3_k127_7979084_85 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000773 60.0
YHH3_k127_7979084_86 Glycosyl transferase family 1 - - - 0.00000001499 61.0
YHH3_k127_7979084_88 Winged helix-turn-helix domain (DUF2582) - - - 0.00002906 52.0
YHH3_k127_7979084_9 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 439.0
YHH3_k127_7979084_90 - - - - 0.0003087 50.0
YHH3_k127_7979084_91 Belongs to the peptidase S8 family - - - 0.0004129 53.0
YHH3_k127_8103487_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 612.0
YHH3_k127_8103487_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 431.0
YHH3_k127_8103487_10 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.0000000000000000000000000000000000006477 160.0
YHH3_k127_8103487_11 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000000000000000000002503 126.0
YHH3_k127_8103487_12 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.0000000000000000000000000002935 132.0
YHH3_k127_8103487_13 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000006572 126.0
YHH3_k127_8103487_14 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000003203 117.0
YHH3_k127_8103487_15 PFAM Transcriptional regulator TrmB - - - 0.00000000000000005085 85.0
YHH3_k127_8103487_16 Protein of unknown function (DUF357) K09728 - - 0.00000000000001932 78.0
YHH3_k127_8103487_17 - - - - 0.00003284 48.0
YHH3_k127_8103487_18 PFAM phosphatidate cytidylyltransferase - - - 0.0002958 51.0
YHH3_k127_8103487_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 335.0
YHH3_k127_8103487_3 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 314.0
YHH3_k127_8103487_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000001412 252.0
YHH3_k127_8103487_5 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000004412 222.0
YHH3_k127_8103487_6 PFAM polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000006966 233.0
YHH3_k127_8103487_7 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000002255 212.0
YHH3_k127_8103487_8 CBS domain K03498 - - 0.000000000000000000000000000000000000000000000000006457 198.0
YHH3_k127_8103487_9 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000004403 158.0
YHH3_k127_8242105_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1281.0
YHH3_k127_8242105_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 3.487e-313 974.0
YHH3_k127_8242105_10 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006959 265.0
YHH3_k127_8242105_11 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001702 238.0
YHH3_k127_8242105_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
YHH3_k127_8242105_13 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000678 215.0
YHH3_k127_8242105_14 HTH-type transcriptional regulatory protein K07728 - - 0.0000000000000000000000000000000000000000000000000000000000004685 222.0
YHH3_k127_8242105_15 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000002813 213.0
YHH3_k127_8242105_16 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000004311 197.0
YHH3_k127_8242105_17 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000001398 186.0
YHH3_k127_8242105_18 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000001183 170.0
YHH3_k127_8242105_19 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000000000000000000000000000005651 165.0
YHH3_k127_8242105_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.825e-214 684.0
YHH3_k127_8242105_20 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000006293 126.0
YHH3_k127_8242105_21 Sulfotransferase domain - - - 0.000000000000000000000000000001394 128.0
YHH3_k127_8242105_22 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000001047 117.0
YHH3_k127_8242105_23 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.0000000000000000000000000006427 126.0
YHH3_k127_8242105_24 deoxyribonuclease I activity K06131,K06915 - - 0.000000000000000000000000009726 118.0
YHH3_k127_8242105_25 Rhomboid family - - - 0.00000000000000000000000005987 119.0
YHH3_k127_8242105_26 - - - - 0.000000000000000000000005181 102.0
YHH3_k127_8242105_27 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.000000000000002268 81.0
YHH3_k127_8242105_28 metallopeptidase activity K01729,K20276 - 4.2.2.3 0.0000000000000423 84.0
YHH3_k127_8242105_29 secreted hydrolase - - - 0.00000000000005707 84.0
YHH3_k127_8242105_3 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 1.333e-202 653.0
YHH3_k127_8242105_30 FlgD Ig-like domain - - - 0.000000002941 70.0
YHH3_k127_8242105_31 - - - - 0.0000001141 58.0
YHH3_k127_8242105_4 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 561.0
YHH3_k127_8242105_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 488.0
YHH3_k127_8242105_6 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 423.0
YHH3_k127_8242105_7 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 392.0
YHH3_k127_8242105_8 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 378.0
YHH3_k127_8242105_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001894 265.0
YHH3_k127_8319657_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 530.0
YHH3_k127_8319657_1 Oxidoreductase family, C-terminal alpha beta domain K13016 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 450.0
YHH3_k127_8319657_10 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000001585 80.0
YHH3_k127_8319657_11 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC - - - 0.0000000000000004894 92.0
YHH3_k127_8319657_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 387.0
YHH3_k127_8319657_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 367.0
YHH3_k127_8319657_4 SAF K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 365.0
YHH3_k127_8319657_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 362.0
YHH3_k127_8319657_6 PFAM acylneuraminate cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000012 241.0
YHH3_k127_8319657_7 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000002437 220.0
YHH3_k127_8319657_8 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing K08068,K18429 - 3.2.1.183,3.2.1.184 0.00000000000000000000000000000000000000000000002298 175.0
YHH3_k127_8319657_9 Succinoglycan biosynthesis protein exoa - - - 0.000000000000000000000000000000000000000001532 169.0
YHH3_k127_8566666_0 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000858 299.0
YHH3_k127_8566666_1 Transposase domain (DUF772) K07481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
YHH3_k127_8566666_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000001377 96.0
YHH3_k127_8566666_3 - - - - 0.00000000000000001017 96.0
YHH3_k127_8566666_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000003251 72.0
YHH3_k127_8566666_5 Type I restriction-modification system methyltransferase subunit - - - 0.000007581 49.0
YHH3_k127_8566666_6 Lrp/AsnC ligand binding domain - - - 0.0001502 51.0
YHH3_k127_8566666_7 - - - - 0.0003034 50.0
YHH3_k127_8590271_0 Aromatic amino acid lyase K01745 - 4.3.1.3 4.872e-267 829.0
YHH3_k127_8590271_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016153,GO:0016829,GO:0016835,GO:0016836,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 4.2.1.49 4.805e-226 713.0
YHH3_k127_8590271_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
YHH3_k127_8590271_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000009718 231.0
YHH3_k127_8590271_12 PFAM Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000001171 214.0
YHH3_k127_8590271_13 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000006474 180.0
YHH3_k127_8590271_14 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000002267 149.0
YHH3_k127_8590271_15 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.0000000000000000000000000000003265 139.0
YHH3_k127_8590271_16 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.000000000000000000000000000008832 128.0
YHH3_k127_8590271_17 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.000000000000000000000000188 106.0
YHH3_k127_8590271_18 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000009762 115.0
YHH3_k127_8590271_19 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000001899 94.0
YHH3_k127_8590271_2 DUF3160 - - - 5.381e-212 681.0
YHH3_k127_8590271_20 COG3316 Transposase and inactivated derivatives K07498 - - 0.0000000000000000001858 91.0
YHH3_k127_8590271_21 COG3316 Transposase and inactivated derivatives K07498 - - 0.000000000000000002009 88.0
YHH3_k127_8590271_22 snRNP Sm proteins K04796 - - 0.00000000000000001139 85.0
YHH3_k127_8590271_23 cellulase activity - - - 0.00000000000357 78.0
YHH3_k127_8590271_24 Periplasmic copper-binding protein (NosD) - - - 0.000000000004525 79.0
YHH3_k127_8590271_25 FlgD Ig-like domain - - - 0.000000000007213 78.0
YHH3_k127_8590271_26 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000001282 65.0
YHH3_k127_8590271_27 FlgD Ig-like domain - - - 0.0000003608 63.0
YHH3_k127_8590271_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 472.0
YHH3_k127_8590271_4 Radical SAM domain protein K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 466.0
YHH3_k127_8590271_5 TIGRFAM Small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 400.0
YHH3_k127_8590271_6 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 358.0
YHH3_k127_8590271_7 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 325.0
YHH3_k127_8590271_8 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 319.0
YHH3_k127_8590271_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000002521 249.0
YHH3_k127_8645331_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 566.0
YHH3_k127_8645331_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 420.0
YHH3_k127_8645331_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000002668 204.0
YHH3_k127_8645331_3 response regulator, receiver K07668,K07669 - - 0.0000000000000000000000000665 110.0
YHH3_k127_8645331_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000001164 53.0
YHH3_k127_869205_0 catalase activity K03781 - 1.11.1.6 2.006e-259 805.0
YHH3_k127_869205_1 Ferrous iron transport B domain protein K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 617.0
YHH3_k127_869205_10 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000434 184.0
YHH3_k127_869205_11 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000003334 158.0
YHH3_k127_869205_12 transcriptional - - - 0.000000000000000000000005605 104.0
YHH3_k127_869205_13 - - - - 0.0000000000004035 77.0
YHH3_k127_869205_14 O-methyltransferase activity - - - 0.0000000000008529 76.0
YHH3_k127_869205_15 extracellular matrix structural constituent - - - 0.0000000002283 73.0
YHH3_k127_869205_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 406.0
YHH3_k127_869205_3 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 362.0
YHH3_k127_869205_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001654 258.0
YHH3_k127_869205_5 FeoA K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001409 248.0
YHH3_k127_869205_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000007219 205.0
YHH3_k127_869205_7 - - - - 0.0000000000000000000000000000000000000000000000000001836 194.0
YHH3_k127_869205_8 transcriptional regulator, AsnC family - - - 0.000000000000000000000000000000000000000000000000000281 190.0
YHH3_k127_869205_9 - - - - 0.00000000000000000000000000000000000000000000000008407 188.0
YHH3_k127_8730734_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 581.0
YHH3_k127_8730734_1 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 454.0
YHH3_k127_8730734_10 Psort location Cytoplasmic, score K06400 - - 0.0000000000000001216 89.0
YHH3_k127_8730734_11 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000002521 80.0
YHH3_k127_8730734_12 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.000000000000004191 76.0
YHH3_k127_8730734_13 PFAM peptidase U32 K08303 - - 0.000000000000005922 77.0
YHH3_k127_8730734_14 KEOPS complex Cgi121-like subunit K09119 - - 0.000000000000006489 83.0
YHH3_k127_8730734_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000002026 73.0
YHH3_k127_8730734_16 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000001504 66.0
YHH3_k127_8730734_17 Peptidase family M28 K05994 - 3.4.11.10 0.0000000865 63.0
YHH3_k127_8730734_18 protein conserved in bacteria (DUF2179) - - - 0.000001791 50.0
YHH3_k127_8730734_19 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000002874 59.0
YHH3_k127_8730734_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003773 279.0
YHH3_k127_8730734_3 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009392 272.0
YHH3_k127_8730734_4 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000904 243.0
YHH3_k127_8730734_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000004352 230.0
YHH3_k127_8730734_6 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000003951 183.0
YHH3_k127_8730734_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001487 169.0
YHH3_k127_8730734_8 Protein of unknown function (DUF3494) - - - 0.000000000000000000000000000000002236 141.0
YHH3_k127_8730734_9 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000002614 130.0
YHH3_k127_8839332_0 acetyltransferase K11206 - - 2.588e-222 700.0
YHH3_k127_8839332_1 Right handed beta helix region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006377 308.0
YHH3_k127_8839332_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000001616 179.0
YHH3_k127_8839332_3 Clostripain family - - - 0.0000000000000000000002483 110.0
YHH3_k127_8839332_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000005201 52.0
YHH3_k127_9093161_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 9.651e-287 914.0
YHH3_k127_9093161_1 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 7.026e-199 628.0
YHH3_k127_9093161_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 379.0
YHH3_k127_9093161_3 ferredoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 332.0
YHH3_k127_9093161_4 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 314.0
YHH3_k127_9093161_5 PFAM Pyruvate K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000002286 179.0
YHH3_k127_9093161_6 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000006309 123.0
YHH3_k127_9093161_7 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000009521 66.0
YHH3_k127_9277276_0 - - - - 0.0000000000000000000003473 102.0
YHH3_k127_9277276_1 Peptidase family M9 N-terminal - - - 0.000179 54.0
YHH3_k127_9277276_2 - - - - 0.0004742 44.0
YHH3_k127_9324204_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 594.0
YHH3_k127_9324204_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 569.0
YHH3_k127_9324204_2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 404.0
YHH3_k127_9324204_3 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 345.0
YHH3_k127_9324204_4 Belongs to the peptidase S16 family K06870 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003293 293.0
YHH3_k127_9324204_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002394 230.0
YHH3_k127_9324204_6 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000002558 219.0
YHH3_k127_9324204_7 Biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000001551 196.0
YHH3_k127_9324204_8 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000001276 143.0
YHH3_k127_9324204_9 PFAM conserved K07027 - - 0.0000002254 62.0
YHH3_k127_9360563_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.263e-239 748.0
YHH3_k127_9360563_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 565.0
YHH3_k127_9360563_10 Sulphur oxygenase reductase K03151,K16952 - 1.13.11.55,2.8.1.4 0.000000000000000000000000000000000000000000000000008827 187.0
YHH3_k127_9360563_11 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000004079 185.0
YHH3_k127_9360563_12 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000174 190.0
YHH3_k127_9360563_13 PFAM TrkA-N domain K03499 - - 0.00000000000000000000000000000000008192 141.0
YHH3_k127_9360563_14 TraB family - - - 0.000000000000000000000000000000002732 138.0
YHH3_k127_9360563_15 Peptidase family M28 K05994 - 3.4.11.10 0.0000000000000000000000000000001588 141.0
YHH3_k127_9360563_16 PFAM type II secretion system K07333 - - 0.0000000000000000000000000002671 132.0
YHH3_k127_9360563_17 Thrombospondin type 3 - - - 0.0000000000000000000000000008409 126.0
YHH3_k127_9360563_18 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000001774 131.0
YHH3_k127_9360563_19 Circadian clock protein KaiC central region K08482 - - 0.0000000000000000000002788 106.0
YHH3_k127_9360563_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 482.0
YHH3_k127_9360563_20 Protein of unknown function (DUF3344) - - - 0.000000000000000000001622 110.0
YHH3_k127_9360563_21 CAAX protease self-immunity K07052 - - 0.0000000000000000001622 98.0
YHH3_k127_9360563_22 PFAM Abortive infection protein - - - 0.00000000000000008945 91.0
YHH3_k127_9360563_23 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000001446 92.0
YHH3_k127_9360563_24 Transglutaminase/protease-like homologues K01406 - 3.4.24.40 0.0000000000000009795 93.0
YHH3_k127_9360563_25 PFAM PKD domain containing protein - - - 0.00000000000001498 84.0
YHH3_k127_9360563_26 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000002544 83.0
YHH3_k127_9360563_27 ATP cone domain K00525,K21636 - 1.1.98.6,1.17.4.1 0.000000000001284 71.0
YHH3_k127_9360563_28 cellulose binding - - - 0.000000000002639 77.0
YHH3_k127_9360563_29 Archaeal Type IV pilin, N-terminal - - - 0.00000000002497 75.0
YHH3_k127_9360563_3 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 442.0
YHH3_k127_9360563_30 - - - - 0.00000000006573 68.0
YHH3_k127_9360563_31 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000003136 63.0
YHH3_k127_9360563_32 - - - - 0.000000003408 64.0
YHH3_k127_9360563_33 transcription regulator activity - - - 0.00000001455 66.0
YHH3_k127_9360563_34 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000003464 67.0
YHH3_k127_9360563_35 transcription regulator activity - - - 0.00000806 57.0
YHH3_k127_9360563_36 Domain of unknown function (DUF5122) beta-propeller - - - 0.00001907 59.0
YHH3_k127_9360563_37 CAAX protease self-immunity K07052 - - 0.00002439 54.0
YHH3_k127_9360563_38 Pfam:DUF1628 - - - 0.00004328 51.0
YHH3_k127_9360563_39 cellulose binding - - - 0.00004595 57.0
YHH3_k127_9360563_4 Type II/IV secretion system protein K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 436.0
YHH3_k127_9360563_5 COG0168 Trk-type K transport systems, membrane components K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 392.0
YHH3_k127_9360563_6 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000005258 227.0
YHH3_k127_9360563_7 TIGRFAM SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006317 231.0
YHH3_k127_9360563_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000131 233.0
YHH3_k127_9360563_9 Fic/DOC family - - - 0.000000000000000000000000000000000000000000000000007681 191.0
YHH3_k127_937307_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.563e-270 861.0
YHH3_k127_937307_1 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.942e-258 805.0
YHH3_k127_937307_10 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000009751 248.0
YHH3_k127_937307_11 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000006169 204.0
YHH3_k127_937307_12 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000434 202.0
YHH3_k127_937307_13 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000005397 199.0
YHH3_k127_937307_14 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000001108 186.0
YHH3_k127_937307_15 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.0000000000000000000000000000000000000000000002689 174.0
YHH3_k127_937307_16 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000002257 129.0
YHH3_k127_937307_17 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.000000000000002515 83.0
YHH3_k127_937307_19 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000002747 72.0
YHH3_k127_937307_2 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 3.464e-254 794.0
YHH3_k127_937307_20 C-terminal domain of CHU protein family - - - 0.000000003729 69.0
YHH3_k127_937307_21 PFAM response regulator receiver K02483 - - 0.0003254 48.0
YHH3_k127_937307_3 Biotin carboxylase C-terminal domain K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 533.0
YHH3_k127_937307_4 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 454.0
YHH3_k127_937307_5 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 432.0
YHH3_k127_937307_6 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 302.0
YHH3_k127_937307_7 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002965 283.0
YHH3_k127_937307_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002301 256.0
YHH3_k127_937307_9 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.000000000000000000000000000000000000000000000000000000000000000000008265 242.0
YHH3_k127_9652147_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 595.0
YHH3_k127_9652147_1 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 479.0
YHH3_k127_9652147_10 Caspase domain - - - 0.0000000615 64.0
YHH3_k127_9652147_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 464.0
YHH3_k127_9652147_3 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 309.0
YHH3_k127_9652147_4 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 314.0
YHH3_k127_9652147_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000561 302.0
YHH3_k127_9652147_6 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001531 268.0
YHH3_k127_9652147_7 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000001788 227.0
YHH3_k127_9652147_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000002114 163.0
YHH3_k127_9652147_9 Phage integrase family K04763 - - 0.00000000000000000000000000000000000002893 154.0
YHH3_k127_9660521_0 COG3316 Transposase and inactivated derivatives K07498 - - 0.00000000000000000000000000000000000000000000003089 177.0
YHH3_k127_9660521_1 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000002917 136.0
YHH3_k127_9660521_2 - - - - 0.000000000000000000000000001232 116.0
YHH3_k127_9660521_3 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000000000000000000002813 122.0
YHH3_k127_9660521_4 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000009945 100.0
YHH3_k127_9660521_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000007397 66.0
YHH3_k127_9660521_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001491 61.0
YHH3_k127_9748645_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1103.0
YHH3_k127_9748645_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 466.0
YHH3_k127_9748645_10 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000002912 192.0
YHH3_k127_9748645_11 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000002297 188.0
YHH3_k127_9748645_12 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.000000000000000000000000000000000000000000001563 171.0
YHH3_k127_9748645_13 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000006273 140.0
YHH3_k127_9748645_14 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000001229 129.0
YHH3_k127_9748645_15 Alpha integrin - - - 0.0000000000000002885 93.0
YHH3_k127_9748645_16 Methionine biosynthesis protein MetW - - - 0.000000000000001436 87.0
YHH3_k127_9748645_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00001114 53.0
YHH3_k127_9748645_18 COG1522 Transcriptional regulators - - - 0.00001359 54.0
YHH3_k127_9748645_19 Alpha-amylase domain - - - 0.00001474 58.0
YHH3_k127_9748645_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 406.0
YHH3_k127_9748645_3 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 354.0
YHH3_k127_9748645_4 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 336.0
YHH3_k127_9748645_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000009014 263.0
YHH3_k127_9748645_6 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002364 265.0
YHH3_k127_9748645_7 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000004733 238.0
YHH3_k127_9748645_8 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000000006218 238.0
YHH3_k127_9748645_9 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000009248 218.0
YHH3_k127_98159_0 Penicillin acylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 353.0
YHH3_k127_9830862_0 Q COG2931 RTX toxins and related Ca2 -binding proteins K01406 - 3.4.24.40 0.00001039 56.0
YHH3_k127_9899796_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 458.0
YHH3_k127_9899796_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002083 263.0
YHH3_k127_9899796_2 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000005152 140.0
YHH3_k127_9899796_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000003872 97.0
YHH3_k127_9954305_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 295.0
YHH3_k127_9954305_1 - - - - 0.0000000003937 61.0