E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate
K00164
-
1.2.4.2
0.0
1522.0
SRR34280936_k127_261860_1
type IV secretion system
-
-
-
0.0
1183.0
SRR34280936_k127_261860_10
NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta)
K01966
-
2.1.3.15,6.4.1.3
9.222e-255
794.0
SRR34280936_k127_261860_60
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor
Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell
Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome
This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K01649
-
2.3.3.13
3.831e-280
869.0
SRR34280936_k127_409830_1060
COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
-
-
-
0.00000000000000000000000000000000000000000001074
170.0
SRR34280936_k127_409830_1061
Domain of unknown function (DUF3597)
-
-
-
0.00000000000000000000000000000000000000000001385
167.0
SRR34280936_k127_409830_1062
once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system
Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K01916
-
6.3.1.5
3.895e-277
860.0
SRR34280936_k127_409830_1080
helix_turn_helix multiple antibiotic resistance protein
-
-
-
0.00000000000000000000000000000000000000004356
164.0
SRR34280936_k127_409830_1081
TrkA-N domain
K03499
-
-
0.000000000000000000000000000000000000000113
156.0
SRR34280936_k127_409830_1082
Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K02956
-
-
0.0000000000000000000000000000000000000001429
154.0
SRR34280936_k127_409830_1083
Glycosyl hydrolase 108
-
-
-
0.0000000000000000000000000000000000000001594
174.0
SRR34280936_k127_409830_1084
-
-
-
-
0.000000000000000000000000000000000000000164
156.0
SRR34280936_k127_409830_1085
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
K04764
-
-
0.0000000000000000000000000000000000000001848
151.0
SRR34280936_k127_409830_1086
50S ribosomal protein L31
K02909
-
-
0.0000000000000000000000000000000000000001869
151.0
SRR34280936_k127_409830_1087
protein conserved in bacteria
K09978
-
-
0.0000000000000000000000000000000000000002441
157.0
SRR34280936_k127_409830_1088
Acetyltransferase (GNAT) domain
-
-
-
0.0000000000000000000000000000000000000003657
163.0
SRR34280936_k127_409830_1089
-
-
-
-
0.0000000000000000000000000000000000000005112
152.0
SRR34280936_k127_409830_109
Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K02435
-
6.3.5.6,6.3.5.7
0.0000000000000000000000000000000000000006862
150.0
SRR34280936_k127_409830_1092
-
-
-
-
0.00000000000000000000000000000000000000156
156.0
SRR34280936_k127_409830_1093
-
-
-
-
0.000000000000000000000000000000000000002058
156.0
SRR34280936_k127_409830_1094
Tetratricopeptide repeat
-
-
-
0.000000000000000000000000000000000000002564
152.0
SRR34280936_k127_409830_1095
-
-
-
-
0.0000000000000000000000000000000000000033
153.0
SRR34280936_k127_409830_1096
Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions
K03530
-
-
0.000000000000000000000000000000000000003382
147.0
SRR34280936_k127_409830_1097
EF hand
-
-
-
0.000000000000000000000000000000000000007852
150.0
SRR34280936_k127_409830_1098
Belongs to the bacterial ribosomal protein bL28 family
K02902
-
-
0.00000000000000000000000000000000000003105
151.0
SRR34280936_k127_409830_1099
PD-(D/E)XK nuclease superfamily
-
-
-
0.00000000000000000000000000000000000003511
147.0
SRR34280936_k127_409830_11
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K02469
-
5.99.1.3
0.0
1467.0
SRR34280936_k127_409830_110
acetyl propionyl-CoA carboxylase, alpha subunit
K01968
-
6.4.1.4
5.999e-275
857.0
SRR34280936_k127_409830_1100
transport system auxiliary component
K18480
-
-
0.00000000000000000000000000000000000004932
150.0
SRR34280936_k127_409830_1101
Cytochrome c biogenesis factor
K02200
-
-
0.0000000000000000000000000000000000000517
153.0
SRR34280936_k127_409830_1102
-
-
-
-
0.00000000000000000000000000000000000005538
151.0
SRR34280936_k127_409830_1103
-
-
-
-
0.00000000000000000000000000000000000006505
149.0
SRR34280936_k127_409830_1104
Bacterial-like globin
K06886
-
-
0.0000000000000000000000000000000000001076
146.0
SRR34280936_k127_409830_1105
Tetratricopeptide repeat
-
-
-
0.0000000000000000000000000000000000001108
157.0
SRR34280936_k127_409830_1106
-
-
-
-
0.0000000000000000000000000000000000001279
153.0
SRR34280936_k127_409830_1107
TIGRFAM conserved repeat domain
-
-
-
0.000000000000000000000000000000000000227
154.0
SRR34280936_k127_409830_1108
Phage head maturation protease
K06904
-
-
0.0000000000000000000000000000000000003245
143.0
SRR34280936_k127_409830_1109
One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K02895
-
-
0.0000000000000000000000000000000000004451
143.0
SRR34280936_k127_409830_111
Protein of unknown function (DUF3376)
-
-
-
3.602e-274
864.0
SRR34280936_k127_409830_1110
overlaps another CDS with the same product name
K08738
-
-
0.0000000000000000000000000000000000004575
144.0
SRR34280936_k127_409830_1111
subunit of a heme lyase
K02200
-
-
0.0000000000000000000000000000000000004621
143.0
SRR34280936_k127_409830_1112
Integral membrane protein linked to a cation
-
-
-
0.0000000000000000000000000000000000005819
144.0
SRR34280936_k127_409830_1113
Protein of unknown function (DUF559)
-
-
-
0.0000000000000000000000000000000000007801
144.0
SRR34280936_k127_409830_1114
Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K04565
-
1.15.1.1
0.000000000000000000000000000000000001052
146.0
SRR34280936_k127_409830_1115
Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K02963
-
-
0.000000000000000000000000000000000001278
138.0
SRR34280936_k127_409830_1116
Copper chaperone PCu(A)C
K09796
-
-
0.000000000000000000000000000000000002319
144.0
SRR34280936_k127_409830_1117
pterin-4-alpha-carbinolamine dehydratase
K01724
-
4.2.1.96
0.000000000000000000000000000000000002576
140.0
SRR34280936_k127_409830_1118
succinate dehydrogenase
K00241
-
-
0.000000000000000000000000000000000002908
141.0
SRR34280936_k127_409830_1119
TIGRFAM conserved repeat domain
-
-
-
0.000000000000000000000000000000000003204
153.0
SRR34280936_k127_409830_112
Glutamine synthetase, catalytic domain
K01915
-
6.3.1.2
3.963e-274
845.0
SRR34280936_k127_409830_1120
PD-(D/E)XK nuclease superfamily
-
-
-
0.000000000000000000000000000000000006578
140.0
SRR34280936_k127_409830_1121
One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K02961
-
-
0.000000000000000000000000000000000008379
137.0
SRR34280936_k127_409830_1122
Belongs to the BolA IbaG family
K05527
-
-
0.000000000000000000000000000000000009091
143.0
SRR34280936_k127_409830_1123
Protein of unknown function (DUF559)
-
-
-
0.00000000000000000000000000000000001372
139.0
SRR34280936_k127_409830_1124
protein conserved in bacteria
K09984
-
-
0.0000000000000000000000000000000000183
136.0
SRR34280936_k127_409830_1125
Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K02109
-
-
0.00000000000000000000000000000000005898
139.0
SRR34280936_k127_409830_1126
META domain
-
-
-
0.0000000000000000000000000000000001177
141.0
SRR34280936_k127_409830_1128
Belongs to the bacterial ribosomal protein bL35 family
K02916
-
-
0.0000000000000000000000000000000001943
133.0
SRR34280936_k127_409830_1129
Phage shock protein B
K03970
-
-
0.0000000000000000000000000000000002435
134.0
SRR34280936_k127_409830_113
Belongs to the class-I aminoacyl-tRNA synthetase family
K04566
-
6.1.1.6
5.397e-273
847.0
SRR34280936_k127_409830_1130
Protein of unknown function (DUF2793)
-
-
-
0.0000000000000000000000000000000003107
136.0
SRR34280936_k127_409830_1131
Carrier of the growing fatty acid chain in fatty acid biosynthesis
K02078
-
-
0.000000000000000000000000000000000322
134.0
SRR34280936_k127_409830_1132
Protein of unknown function (DUF559)
-
-
-
0.0000000000000000000000000000000005874
137.0
SRR34280936_k127_409830_1133
-
-
-
-
0.0000000000000000000000000000000006644
139.0
SRR34280936_k127_409830_1134
-
-
-
-
0.0000000000000000000000000000000006916
143.0
SRR34280936_k127_409830_1135
-
-
-
-
0.000000000000000000000000000000001216
134.0
SRR34280936_k127_409830_1136
Phage tail tube protein, GTA-gp10
-
-
-
0.000000000000000000000000000000001619
133.0
SRR34280936_k127_409830_1137
Produces ATP from ADP in the presence of a proton gradient across the membrane
K02113,K02114
-
-
0.00000000000000000000000000000000332
130.0
SRR34280936_k127_409830_1138
Outer membrane protein (OmpH-like)
-
-
-
0.000000000000000000000000000000004698
138.0
SRR34280936_k127_409830_1139
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Belongs to the bacterial ribosomal protein bL32 family
K02911
-
-
0.000000000000000000000000000002957
119.0
SRR34280936_k127_409830_116
Glutamine synthetase, catalytic domain
K01915
-
6.3.1.2
4.105e-270
835.0
SRR34280936_k127_409830_1160
-
-
-
-
0.000000000000000000000000000004382
128.0
SRR34280936_k127_409830_1161
Flavinator of succinate dehydrogenase
K09159
-
-
0.000000000000000000000000000005003
124.0
SRR34280936_k127_409830_1162
2Fe-2S iron-sulfur cluster binding domain
-
-
-
0.000000000000000000000000000009562
121.0
SRR34280936_k127_409830_1163
-
-
-
-
0.00000000000000000000000000001483
121.0
SRR34280936_k127_409830_1164
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
-
-
-
0.00000000000000000000000000002135
122.0
SRR34280936_k127_409830_1165
Bacterial regulatory proteins, tetR family
-
-
-
0.00000000000000000000000000002782
124.0
SRR34280936_k127_409830_1166
Protein of unknown function (DUF1282)
-
-
-
0.0000000000000000000000000000323
127.0
SRR34280936_k127_409830_1167
Domain of unknown function (DUF4170)
-
-
-
0.00000000000000000000000000004078
117.0
SRR34280936_k127_409830_1168
Staphylococcal nuclease homologue
-
-
-
0.00000000000000000000000000004581
127.0
SRR34280936_k127_409830_1169
function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex
K02116
-
-
0.00000000000000000000000000009498
120.0
SRR34280936_k127_409830_117
2-nitropropane dioxygenase
-
-
-
2.562e-268
829.0
SRR34280936_k127_409830_1170
-
-
-
-
0.0000000000000000000000000001015
121.0
SRR34280936_k127_409830_1171
PilZ domain
-
-
-
0.000000000000000000000000000133
119.0
SRR34280936_k127_409830_1172
Protein of unknown function (DUF1467)
-
-
-
0.0000000000000000000000000002046
118.0
SRR34280936_k127_409830_1173
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K02110
-
-
0.0000000000000000000000000003248
117.0
SRR34280936_k127_409830_1174
Septum formation initiator
-
-
-
0.00000000000000000000000000034
116.0
SRR34280936_k127_409830_1175
Serine kinase of the HPr protein, regulates carbohydrate metabolism
-
-
-
0.000000000000000000000000000773
119.0
SRR34280936_k127_409830_1176
-
-
-
-
0.000000000000000000000000001019
121.0
SRR34280936_k127_409830_1177
-
-
-
-
0.000000000000000000000000001019
119.0
SRR34280936_k127_409830_1178
Protein of unknown function (DUF1294)
-
-
-
0.000000000000000000000000001066
116.0
SRR34280936_k127_409830_1179
Two component signalling adaptor domain
K03408
-
-
0.00000000000000000000000000118
120.0
SRR34280936_k127_409830_118
Flavin-binding monooxygenase-like
K18277
-
1.14.13.148
2.345e-267
827.0
SRR34280936_k127_409830_1180
-
-
-
-
0.00000000000000000000000000201
117.0
SRR34280936_k127_409830_1181
Preprotein translocase subunit SecG
K03075
-
-
0.000000000000000000000000002341
116.0
SRR34280936_k127_409830_1182
transcriptional
-
-
-
0.000000000000000000000000002632
115.0
SRR34280936_k127_409830_1183
Protein of unknown function (DUF559)
-
-
-
0.000000000000000000000000002748
116.0
SRR34280936_k127_409830_1184
Protein conserved in bacteria
-
-
-
0.000000000000000000000000002824
120.0
SRR34280936_k127_409830_1185
Prokaryotic dksA/traR C4-type zinc finger
-
-
-
0.000000000000000000000000003475
116.0
SRR34280936_k127_409830_1186
-
-
-
-
0.000000000000000000000000005331
115.0
SRR34280936_k127_409830_1187
FKBP-type peptidyl-prolyl cis-trans isomerase
K03772
-
5.2.1.8
0.000000000000000000000000007348
126.0
SRR34280936_k127_409830_1188
NLP P60 protein
-
-
-
0.000000000000000000000000008859
114.0
SRR34280936_k127_409830_1189
-
-
-
-
0.00000000000000000000000001074
114.0
SRR34280936_k127_409830_119
COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes
K00382
-
1.8.1.4
2.585e-267
828.0
SRR34280936_k127_409830_1190
-
-
-
-
0.00000000000000000000000001325
114.0
SRR34280936_k127_409830_1191
NifU homolog involved in Fe-S cluster formation
-
-
-
0.00000000000000000000000001669
115.0
SRR34280936_k127_409830_1192
Belongs to the bacterial ribosomal protein bS21 family
K02970
-
-
0.00000000000000000000000001676
114.0
SRR34280936_k127_409830_1193
Virulence-associated protein
K18829
-
-
0.00000000000000000000000003246
110.0
SRR34280936_k127_409830_1194
Putative auto-transporter adhesin, head GIN domain
-
-
-
0.00000000000000000000000003366
119.0
SRR34280936_k127_409830_1195
-
-
-
-
0.00000000000000000000000004045
115.0
SRR34280936_k127_409830_1196
copG family
-
-
-
0.0000000000000000000000001335
107.0
SRR34280936_k127_409830_1197
involved in the hydrocarbon hydroxylating system to convert conversion of dodecane to lauric acid, which transfers electrons from NADH to rubredoxin reductase and then through rubredoxin to alkane 1 monooxygenase
-
-
-
0.0000000000000000000000001677
106.0
SRR34280936_k127_409830_1198
-
-
-
-
0.0000000000000000000000001899
108.0
SRR34280936_k127_409830_1199
Proprotein convertase P-domain
-
-
-
0.0000000000000000000000002451
123.0
SRR34280936_k127_409830_12
Belongs to the CarB family
K01955
-
6.3.5.5
0.0
1444.0
SRR34280936_k127_409830_120
Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K02434
-
6.3.5.6,6.3.5.7
1.858e-265
823.0
SRR34280936_k127_409830_1200
domain protein
K07461
-
-
0.0000000000000000000000003607
112.0
SRR34280936_k127_409830_1201
-
-
-
-
0.0000000000000000000000005853
111.0
SRR34280936_k127_409830_1202
PilZ domain
-
-
-
0.000000000000000000000000634
108.0
SRR34280936_k127_409830_1203
-
-
-
-
0.0000000000000000000000009875
111.0
SRR34280936_k127_409830_1204
Glycine zipper 2TM domain
-
-
-
0.000000000000000000000001423
108.0
SRR34280936_k127_409830_1205
protein conserved in bacteria
K09794
-
-
0.000000000000000000000001994
105.0
SRR34280936_k127_409830_1206
Short repeat of unknown function (DUF308)
-
-
-
0.000000000000000000000003949
109.0
SRR34280936_k127_409830_1208
Ribonuclease toxin, BrnT, of type II toxin-antitoxin system
K09803
-
-
0.000000000000000000000006304
105.0
SRR34280936_k127_409830_1209
Pilus assembly protein PilZ
-
-
-
0.00000000000000000000002576
103.0
SRR34280936_k127_409830_121
amino acid peptide transporter
K03305
-
-
2.385e-265
820.0
SRR34280936_k127_409830_1210
Pfam:DUF1049
K08992
-
-
0.00000000000000000000004937
101.0
SRR34280936_k127_409830_1211
ThiS family
-
-
-
0.00000000000000000000005169
101.0
SRR34280936_k127_409830_1212
-
-
-
-
0.00000000000000000000005533
107.0
SRR34280936_k127_409830_1213
-
-
-
-
0.00000000000000000000006039
104.0
SRR34280936_k127_409830_1214
COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)
K04762
-
-
0.0000000000000000000001184
104.0
SRR34280936_k127_409830_1215
Belongs to the universal ribosomal protein uL29 family
K02904
-
-
0.0000000000000000000005337
96.0
SRR34280936_k127_409830_1216
Domain of unknown function (DUF1902)
-
-
-
0.0000000000000000000008152
99.0
SRR34280936_k127_409830_1217
Protein of unknown function (DUF2892)
-
-
-
0.0000000000000000000009582
95.0
SRR34280936_k127_409830_1218
addiction module antidote protein
-
-
-
0.000000000000000000001336
99.0
SRR34280936_k127_409830_1219
-
-
-
-
0.000000000000000000001441
102.0
SRR34280936_k127_409830_122
Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K00764
-
2.4.2.14
2.654e-265
822.0
SRR34280936_k127_409830_1220
-
-
-
-
0.000000000000000000001757
96.0
SRR34280936_k127_409830_1221
-
-
-
-
0.000000000000000000002958
99.0
SRR34280936_k127_409830_1222
-
-
-
-
0.000000000000000000004576
94.0
SRR34280936_k127_409830_1223
-
-
-
-
0.000000000000000000006238
94.0
SRR34280936_k127_409830_1224
Protein of unknown function (DUF2842)
-
-
-
0.00000000000000000001041
95.0
SRR34280936_k127_409830_1225
-
-
-
-
0.0000000000000000000153
93.0
SRR34280936_k127_409830_1226
-
-
-
-
0.00000000000000000005147
95.0
SRR34280936_k127_409830_1227
Ribosomal protein L30
K02907
-
-
0.00000000000000000007141
89.0
SRR34280936_k127_409830_1228
-
-
-
-
0.0000000000000000003999
90.0
SRR34280936_k127_409830_1229
HicA toxin of bacterial toxin-antitoxin,
-
-
-
0.000000000000000000509
88.0
SRR34280936_k127_409830_123
Belongs to the glycosyl hydrolase 43 family
-
-
-
1.373e-264
824.0
SRR34280936_k127_409830_1230
-
-
-
-
0.0000000000000000005438
91.0
SRR34280936_k127_409830_1231
Heat shock protein
K03668
-
-
0.000000000000000001213
96.0
SRR34280936_k127_409830_1232
Antitoxin component of a toxin-antitoxin (TA) module
-
-
-
0.00000000000000000142
86.0
SRR34280936_k127_409830_1233
-
-
-
-
0.000000000000000001446
99.0
SRR34280936_k127_409830_1234
-
-
-
-
0.000000000000000002628
90.0
SRR34280936_k127_409830_1235
AAA-like domain
-
-
-
0.00000000000000000445
98.0
SRR34280936_k127_409830_1236
-
-
-
-
0.000000000000000006831
88.0
SRR34280936_k127_409830_1237
oxidation-reduction process
K09022
-
3.5.99.10
0.000000000000000008402
94.0
SRR34280936_k127_409830_1238
-
-
-
-
0.00000000000000001236
82.0
SRR34280936_k127_409830_1239
Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K09888
-
-
0.00000000000000001334
87.0
SRR34280936_k127_409830_124
Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K01874
-
6.1.1.10
1.825e-264
823.0
SRR34280936_k127_409830_1240
Cytochrome oxidase maturation protein cbb3-type
-
-
-
0.00000000000000005094
83.0
SRR34280936_k127_409830_1241
-
-
-
-
0.00000000000000009947
81.0
SRR34280936_k127_409830_1242
-
-
-
-
0.0000000000000001012
90.0
SRR34280936_k127_409830_1243
addiction module killer protein
-
-
-
0.0000000000000003057
80.0
SRR34280936_k127_409830_1244
-
-
-
-
0.0000000000000004461
87.0
SRR34280936_k127_409830_1246
Pectate lyase superfamily protein
-
-
-
0.000000000000000982
92.0
SRR34280936_k127_409830_1247
ergosterol biosynthetic process
K02291
-
2.5.1.32,2.5.1.99
0.000000000000001441
84.0
SRR34280936_k127_409830_1248
-
-
-
-
0.000000000000001891
83.0
SRR34280936_k127_409830_1249
-
-
-
-
0.000000000000004781
87.0
SRR34280936_k127_409830_125
helicase
K16899
-
3.6.4.12
2.173e-264
848.0
SRR34280936_k127_409830_1250
-
-
-
-
0.00000000000001061
77.0
SRR34280936_k127_409830_1251
A nuclease family of the HNH/ENDO VII superfamily with conserved AHH
-
-
-
0.00000000000002527
78.0
SRR34280936_k127_409830_1253
transcriptional regulator
-
-
-
0.00000000000002737
80.0
SRR34280936_k127_409830_1254
Peptidase inhibitor I78 family
-
-
-
0.00000000000005213
76.0
SRR34280936_k127_409830_1255
Protein of unknown function (DUF1192)
-
-
-
0.00000000000005451
74.0
SRR34280936_k127_409830_1256
-
-
-
-
0.00000000000005977
85.0
SRR34280936_k127_409830_1257
Cbb3-type cytochrome oxidase component FixQ
K00407
-
-
0.00000000000007826
74.0
SRR34280936_k127_409830_1258
-
-
-
-
0.0000000000000842
85.0
SRR34280936_k127_409830_1259
-
-
-
-
0.0000000000001629
81.0
SRR34280936_k127_409830_126
Peptidase, M28
-
-
-
4.799e-264
823.0
SRR34280936_k127_409830_1260
-
-
-
-
0.0000000000001692
72.0
SRR34280936_k127_409830_1261
Phage head-tail joining protein
-
-
-
0.0000000000001837
75.0
SRR34280936_k127_409830_1262
YnbE-like lipoprotein
-
-
-
0.0000000000002254
75.0
SRR34280936_k127_409830_1263
-
-
-
-
0.0000000000003394
77.0
SRR34280936_k127_409830_1264
Periplasmic protein TonB, links inner and outer membranes
K03832
-
-
0.0000000000003603
78.0
SRR34280936_k127_409830_1265
-
-
-
-
0.0000000000005727
72.0
SRR34280936_k127_409830_1266
-
-
-
-
0.000000000000611
76.0
SRR34280936_k127_409830_1267
-
-
-
-
0.000000000001193
81.0
SRR34280936_k127_409830_1269
-
-
-
-
0.000000000003065
76.0
SRR34280936_k127_409830_127
Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K01939
-
6.3.4.4
1.112e-263
818.0
SRR34280936_k127_409830_1270
-
-
-
-
0.000000000004126
78.0
SRR34280936_k127_409830_1271
-
-
-
-
0.000000000008197
74.0
SRR34280936_k127_409830_1273
-
-
-
-
0.0000000000322
70.0
SRR34280936_k127_409830_1274
PspC domain
K03973
-
-
0.00000000004435
67.0
SRR34280936_k127_409830_1275
-
-
-
-
0.00000000009225
67.0
SRR34280936_k127_409830_1276
-
-
-
-
0.0000000002074
66.0
SRR34280936_k127_409830_1277
Helix-turn-helix domain
-
-
-
0.0000000003788
63.0
SRR34280936_k127_409830_1278
-
-
-
-
0.000000000414
70.0
SRR34280936_k127_409830_1279
-
-
-
-
0.0000000007808
64.0
SRR34280936_k127_409830_128
Flp pilus assembly protein, ATPase CpaF
K02283
-
-
1.907e-263
818.0
SRR34280936_k127_409830_1280
-
-
-
-
0.000000000804
61.0
SRR34280936_k127_409830_1282
Putative zinc ribbon domain
-
-
-
0.000000003385
61.0
SRR34280936_k127_409830_1284
-
-
-
-
0.00000001276
63.0
SRR34280936_k127_409830_1286
-
-
-
-
0.00000001619
61.0
SRR34280936_k127_409830_1287
-
-
-
-
0.00000002972
57.0
SRR34280936_k127_409830_129
Histidine kinase
K13587
-
2.7.13.3
4.354e-263
832.0
SRR34280936_k127_409830_1292
receptor
-
-
-
0.0000001373
56.0
SRR34280936_k127_409830_1293
COG1961 Site-specific recombinases, DNA invertase Pin homologs
-
-
-
0.0000001544
53.0
SRR34280936_k127_409830_1294
Protein of unknown function (DUF541)
K09807
GO:0005575,GO:0005623,GO:0042597,GO:0044464
-
0.0000001765
61.0
SRR34280936_k127_409830_1295
-
-
-
-
0.0000001855
57.0
SRR34280936_k127_409830_1299
-
-
-
-
0.0000002703
55.0
SRR34280936_k127_409830_13
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane
K03070
-
-
0.0
1423.0
SRR34280936_k127_409830_130
ABC-type multidrug transport system, ATPase and permease
K06147
-
-
5.799e-263
821.0
SRR34280936_k127_409830_1300
-
-
-
-
0.000000313
55.0
SRR34280936_k127_409830_1302
-
-
-
-
0.0000003845
56.0
SRR34280936_k127_409830_1303
Bacteriophage replication gene A protein (GPA)
-
-
-
0.0000003845
56.0
SRR34280936_k127_409830_1305
Phage tail-collar fibre protein
-
-
-
0.0000005858
62.0
SRR34280936_k127_409830_1306
Transport and Golgi organisation 2
K19562
-
2.6.1.62,6.3.3.3
0.0000008227
55.0
SRR34280936_k127_409830_131
cytochrome C
K02198
-
-
1.58e-262
824.0
SRR34280936_k127_409830_1312
-
-
-
-
0.00001688
53.0
SRR34280936_k127_409830_1315
-
-
-
-
0.000043
53.0
SRR34280936_k127_409830_1316
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase
K14162
-
2.7.7.7
0.0000598
46.0
SRR34280936_k127_409830_1318
-
-
-
-
0.00008485
55.0
SRR34280936_k127_409830_132
Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth
K00088
-
1.1.1.205
1.71e-261
812.0
SRR34280936_k127_409830_1323
ester cyclase
-
-
-
0.0002928
51.0
SRR34280936_k127_409830_1324
Protein of unknown function (DUF3383)
-
-
-
0.0004155
54.0
SRR34280936_k127_409830_1325
hydrolase
K01048
-
3.1.1.5
0.0004455
46.0
SRR34280936_k127_409830_1327
Recombinase zinc beta ribbon domain
-
-
-
0.0006046
44.0
SRR34280936_k127_409830_1328
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
K03701
-
-
0.0007843
43.0
SRR34280936_k127_409830_1329
Uncharacterised protein conserved in bacteria (DUF2336)
-
-
-
0.0007971
51.0
SRR34280936_k127_409830_133
Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12
K14441
-
2.8.4.4
9.39e-261
808.0
SRR34280936_k127_409830_134
An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism
K01961
-
6.3.4.14,6.4.1.2
9.988e-260
803.0
SRR34280936_k127_409830_135
NADH ubiquinone oxidoreductase subunit
K00342
-
1.6.5.3
1.572e-259
809.0
SRR34280936_k127_409830_136
Nitrogen fixation protein fixG
-
-
-
2.092e-259
807.0
SRR34280936_k127_409830_137
Elongation factor G, domain IV
K02355
-
-
9.104e-259
814.0
SRR34280936_k127_409830_138
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K00335
-
1.6.5.3
3.571e-256
793.0
SRR34280936_k127_409830_139
Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K01756
-
4.3.2.2
4.725e-256
793.0
SRR34280936_k127_409830_14
Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K03168
-
5.99.1.2
0.0
1359.0
SRR34280936_k127_409830_140
COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
K01897
-
6.2.1.3
1.252e-255
798.0
SRR34280936_k127_409830_141
Alpha-amylase domain
-
-
-
5.797e-255
801.0
SRR34280936_k127_409830_142
Belongs to the citrate synthase family
K01647
-
2.3.3.1
6.886e-254
786.0
SRR34280936_k127_409830_143
Alpha-amylase domain
K01187
-
3.2.1.20
8.134e-254
795.0
SRR34280936_k127_409830_144
Tryptophan halogenase
K14266
-
1.14.19.9
1.188e-253
791.0
SRR34280936_k127_409830_145
Tryptophan halogenase
K14266
-
1.14.19.9
1.375e-253
790.0
SRR34280936_k127_409830_146
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K12256
-
2.6.1.113
9.125e-253
785.0
SRR34280936_k127_409830_147
glucuronate isomerase
K01812
-
5.3.1.12
4.585e-252
782.0
SRR34280936_k127_409830_148
Glutamate synthase
K00266
-
1.4.1.13,1.4.1.14
6.045e-252
783.0
SRR34280936_k127_409830_149
Belongs to the isocitrate and isopropylmalate dehydrogenases family
K00031
-
1.1.1.42
2.061e-251
778.0
SRR34280936_k127_409830_15
Oxidizes proline to glutamate for use as a carbon and nitrogen source
K13821
-
1.2.1.88,1.5.5.2
0.0
1356.0
SRR34280936_k127_409830_150
A circularly permuted ATPgrasp
-
-
-
8.87e-251
782.0
SRR34280936_k127_409830_151
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP
K09458
-
2.3.1.179
2.999e-248
769.0
SRR34280936_k127_409830_152
Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K00789
-
2.5.1.6
3.288e-248
769.0
SRR34280936_k127_409830_153
Alkyl sulfatase dimerisation
-
-
-
4.132e-248
781.0
SRR34280936_k127_409830_154
ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K03544
-
-
3.726e-247
766.0
SRR34280936_k127_409830_155
Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K01657
-
4.1.3.27
1.019e-246
770.0
SRR34280936_k127_409830_156
The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
K01696
-
4.2.1.20
9.644e-245
760.0
SRR34280936_k127_409830_157
metallo-beta-lactamase
K12574
-
-
2.953e-244
765.0
SRR34280936_k127_409830_158
Major Facilitator
-
-
-
9.939e-244
765.0
SRR34280936_k127_409830_159
COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
K00666,K18688
-
6.2.1.42
1.064e-243
762.0
SRR34280936_k127_409830_16
Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction
K00962
-
2.7.7.8
0.0
1342.0
SRR34280936_k127_409830_160
TonB-dependent receptor
-
-
-
8.223e-243
774.0
SRR34280936_k127_409830_161
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K00333
-
1.6.5.3
8.356e-243
752.0
SRR34280936_k127_409830_162
Belongs to the thiolase family
K00626
-
2.3.1.9
8.633e-242
749.0
SRR34280936_k127_409830_163
This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K02358
-
-
3.948e-241
747.0
SRR34280936_k127_409830_164
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
K03106
-
3.6.5.4
1.274e-240
751.0
SRR34280936_k127_409830_165
Catalyzes the formation of methanethiol and 2-ocobutanoate from L-methionine
K01761
-
4.4.1.11
5.825e-240
745.0
SRR34280936_k127_409830_166
Histidine kinase
-
-
-
8.261e-240
764.0
SRR34280936_k127_409830_167
COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
-
-
-
1.066e-239
752.0
SRR34280936_k127_409830_168
COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
K00666,K20034
-
6.2.1.44
1.089e-239
752.0
SRR34280936_k127_409830_169
amidohydrolase
-
-
-
1.107e-239
747.0
SRR34280936_k127_409830_17
In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K02335
-
2.7.7.7
0.0
1334.0
SRR34280936_k127_409830_170
Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
K03455,K11747
-
-
2.596e-239
753.0
SRR34280936_k127_409830_171
Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily
K00121
-
1.1.1.1,1.1.1.284
3.411e-238
739.0
SRR34280936_k127_409830_172
Belongs to the thiolase family
K00626
-
2.3.1.9
3.642e-238
745.0
SRR34280936_k127_409830_173
Belongs to the glycosyl hydrolase 43 family
-
-
-
9.495e-238
741.0
SRR34280936_k127_409830_174
RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication
K02316
-
-
1.126e-237
750.0
SRR34280936_k127_409830_175
COG0477 Permeases of the major facilitator superfamily
K16211
-
-
2.26e-236
740.0
SRR34280936_k127_409830_176
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
K04485
-
-
1.912e-235
735.0
SRR34280936_k127_409830_177
The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
K00325
-
1.6.1.2
4.095e-235
734.0
SRR34280936_k127_409830_178
5-aminolevulinic acid synthase
K00643
-
2.3.1.37
6.123e-235
731.0
SRR34280936_k127_409830_179
The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently
K03076
-
-
6.441e-235
733.0
SRR34280936_k127_409830_18
Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K01872
-
6.1.1.7
0.0
1320.0
SRR34280936_k127_409830_180
Major facilitator superfamily
K08191
-
-
6.705e-235
731.0
SRR34280936_k127_409830_181
May be involved in recombinational repair of damaged DNA
K03631
-
-
9.758e-235
737.0
SRR34280936_k127_409830_182
Saccharopine dehydrogenase
K00290
-
1.5.1.7
1.078e-234
729.0
SRR34280936_k127_409830_183
Acyl-CoA dehydrogenase, C-terminal domain
K14448
-
1.3.8.12
1.378e-233
736.0
SRR34280936_k127_409830_184
Cysteine-rich domain
K00113
-
1.1.5.3
1.709e-233
730.0
SRR34280936_k127_409830_185
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K00822
-
2.6.1.18
5e-232
724.0
SRR34280936_k127_409830_186
Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs
K08300
-
3.1.26.12
8.302e-232
748.0
SRR34280936_k127_409830_187
Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family
K03455
-
-
5.213e-230
726.0
SRR34280936_k127_409830_188
protein involved in exopolysaccharide biosynthesis
K16554
-
-
6.934e-230
732.0
SRR34280936_k127_409830_189
Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis
K01689
-
4.2.1.11
8.049e-230
717.0
SRR34280936_k127_409830_19
Helicase
K03722
-
3.6.4.12
0.0
1292.0
SRR34280936_k127_409830_190
Belongs to the GMC oxidoreductase family
-
-
-
1.224e-229
722.0
SRR34280936_k127_409830_191
COG1228 Imidazolonepropionase and related amidohydrolases
-
-
-
1.72e-229
718.0
SRR34280936_k127_409830_192
Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K04094
-
2.1.1.74
5.781e-229
728.0
SRR34280936_k127_409830_193
DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Belongs to the type-B carboxylesterase lipase family
K03929
-
-
6.607e-227
712.0
SRR34280936_k127_409830_2
Domain of unknown function DUF11
-
-
-
0.0
1984.0
SRR34280936_k127_409830_20
COG1629 Outer membrane receptor proteins, mostly Fe transport
K02014
-
-
0.0
1285.0
SRR34280936_k127_409830_200
Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
K00831
-
2.6.1.52
7.345e-227
706.0
SRR34280936_k127_409830_201
mandelate racemase muconate lactonizing
K01684,K01781,K08323
-
4.2.1.6,4.2.1.8,5.1.2.2
6.576e-226
702.0
SRR34280936_k127_409830_202
Von Willebrand factor A
K09989
-
-
6.62e-226
703.0
SRR34280936_k127_409830_203
Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
-
-
-
8.769e-226
710.0
SRR34280936_k127_409830_204
Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate
K06447
-
1.2.1.71
9.464e-226
708.0
SRR34280936_k127_409830_205
Belongs to the DNA photolyase family
K01669
-
4.1.99.3
2.327e-225
707.0
SRR34280936_k127_409830_206
Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system
K11072,K11076
-
3.6.3.31
6.439e-225
699.0
SRR34280936_k127_409830_207
Transporter
-
-
-
5.018e-224
708.0
SRR34280936_k127_409830_208
Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation
K13598
-
2.7.13.3
1.015e-223
715.0
SRR34280936_k127_409830_209
The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
K00162
-
1.2.4.1
5.019e-223
698.0
SRR34280936_k127_409830_21
Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K00990
-
2.7.7.59
0.0
1282.0
SRR34280936_k127_409830_210
sugar transferase
-
-
-
4.75e-222
695.0
SRR34280936_k127_409830_211
acyl-CoA dehydrogenase
-
-
-
5.07e-222
691.0
SRR34280936_k127_409830_212
Belongs to the 'phage' integrase family
-
-
-
1.671e-221
691.0
SRR34280936_k127_409830_213
acyl-CoA dehydrogenase
K00249
-
1.3.8.7
4.496e-221
690.0
SRR34280936_k127_409830_214
signal peptide peptidase
K04773
-
-
7.022e-221
701.0
SRR34280936_k127_409830_215
Dicarboxylate transport
-
-
-
8.686e-221
722.0
SRR34280936_k127_409830_216
ABC-type sugar transport system periplasmic component
K02027
-
-
9.812e-221
694.0
SRR34280936_k127_409830_217
Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K00600
-
2.1.2.1
1.092e-220
692.0
SRR34280936_k127_409830_218
gamma-glutamyltranspeptidase
K00681
-
2.3.2.2,3.4.19.13
1.382e-220
703.0
SRR34280936_k127_409830_219
Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA
K00253
-
1.3.8.4
9.785e-220
684.0
SRR34280936_k127_409830_22
Belongs to the ClpA ClpB family
K03694
-
-
0.0
1273.0
SRR34280936_k127_409830_220
Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K03431
-
5.4.2.10
1.559e-218
684.0
SRR34280936_k127_409830_221
Belongs to the thiolase family
K00626,K00632
-
2.3.1.16,2.3.1.9
5.494e-218
682.0
SRR34280936_k127_409830_222
pectate lyase
-
-
-
1.226e-217
683.0
SRR34280936_k127_409830_223
Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations
K01241
-
3.2.2.4
5.102e-217
682.0
SRR34280936_k127_409830_224
this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K03667
-
-
5.198e-217
680.0
SRR34280936_k127_409830_225
Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Domain present in phytochromes and cGMP-specific phosphodiesterases.
-
-
-
1.017e-214
687.0
SRR34280936_k127_409830_232
Transporter
K02429
-
-
1.72e-214
672.0
SRR34280936_k127_409830_233
Transcriptional regulator
K07110
-
-
6.479e-214
673.0
SRR34280936_k127_409830_234
COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains)
K08309
-
-
1.396e-213
682.0
SRR34280936_k127_409830_235
Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
K13599
-
-
1.954e-213
672.0
SRR34280936_k127_409830_236
Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains
K02481
-
-
4.096e-211
666.0
SRR34280936_k127_409830_237
Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K00526
-
1.17.4.1
1.378e-210
656.0
SRR34280936_k127_409830_238
COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes
-
-
-
1.114e-208
659.0
SRR34280936_k127_409830_239
carnitine dehydratase
K14470
-
5.4.1.3
1.481e-208
653.0
SRR34280936_k127_409830_24
Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K02355
-
-
0.0
1262.0
SRR34280936_k127_409830_240
Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K01875
-
6.1.1.11
1.541e-207
651.0
SRR34280936_k127_409830_241
ABC-type transport system, involved in lipoprotein release, permease component
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K03072
-
-
9.607e-205
649.0
SRR34280936_k127_409830_246
Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K00383
-
1.8.1.7
1.223e-204
645.0
SRR34280936_k127_409830_247
dehydratase
K07749
-
2.8.3.16
1.25e-204
643.0
SRR34280936_k127_409830_248
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K01255
-
3.4.11.1
2.031e-204
646.0
SRR34280936_k127_409830_249
Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase
ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K01338
-
3.4.21.53
0.0
1255.0
SRR34280936_k127_409830_250
Histidine kinase
-
-
-
4.235e-204
644.0
SRR34280936_k127_409830_251
Belongs to the peptidase M16 family
K07263
-
-
2.681e-203
666.0
SRR34280936_k127_409830_252
Phosphoribosylformylglycinamidine cyclo-ligase
K01933
-
6.3.3.1
4.462e-203
642.0
SRR34280936_k127_409830_253
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K03040
-
2.7.7.6
5.819e-203
634.0
SRR34280936_k127_409830_254
Belongs to the 'phage' integrase family
-
-
-
2.764e-202
636.0
SRR34280936_k127_409830_255
Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K00133
-
1.2.1.11
3.538e-202
632.0
SRR34280936_k127_409830_256
Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K00053
-
1.1.1.86
6.249e-202
631.0
SRR34280936_k127_409830_257
Protein of unknown function (DUF1016)
-
-
-
8.492e-202
633.0
SRR34280936_k127_409830_258
Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K00620
-
2.3.1.1,2.3.1.35
2.619e-201
632.0
SRR34280936_k127_409830_259
Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily
Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K00013
-
1.1.1.23
8.924e-199
631.0
SRR34280936_k127_409830_265
Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K06131
-
-
2.993e-198
630.0
SRR34280936_k127_409830_266
Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K03684
-
3.1.13.5
8.581e-198
622.0
SRR34280936_k127_409830_267
Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO(2)
CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
K09952
-
-
0.0
1248.0
SRR34280936_k127_409830_270
Belongs to the CarA family
K01956
-
6.3.5.5
9.662e-197
620.0
SRR34280936_k127_409830_271
Major facilitator superfamily
K08218
-
-
1.707e-196
621.0
SRR34280936_k127_409830_272
Aldehyde dehydrogenase family
-
-
-
2.986e-196
623.0
SRR34280936_k127_409830_273
Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K07277
-
-
0.0
1205.0
SRR34280936_k127_409830_290
ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force
Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA
Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K03147
-
4.1.99.17
0.0
1103.0
SRR34280936_k127_409830_410
Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis
Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components
Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S
Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA
Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K01972
-
6.5.1.2
0.0
1057.0
SRR34280936_k127_409830_510
Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth
Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits
Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins
Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism
Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates
K01937
-
6.3.4.2
2.172e-315
970.0
SRR34280936_k127_409830_660
Belongs to the class-I aminoacyl-tRNA synthetase family
Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity
Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)
Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)
NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another
Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides
Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism
Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate
Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage
Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length
Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP
Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs
RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs
Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site
An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity
FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation
COG0156 7-keto-8-aminopelargonate synthetase and related enzymes
K00639,K00652
-
2.3.1.29,2.3.1.47
7.633e-235
730.0
SRR34280936_k127_852714_230
PD-(D/E)XK nuclease superfamily
-
-
-
0.000000000000000000000000000000000000002716
149.0
SRR34280936_k127_852714_231
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K02518
-
-
0.000000000000000000000000000000000000003071
147.0
SRR34280936_k127_852714_232
Protein of unknown function (DUF1176)
-
-
-
0.00000000000000000000000000000000000000547
159.0
SRR34280936_k127_852714_233
Flagellar hook-basal body complex protein FliE
K02408
-
-
0.0000000000000000000000000000000000004438
142.0
SRR34280936_k127_852714_234
Protein of unknown function (Hypoth_ymh)
-
-
-
0.000000000000000000000000000000000005831
139.0
SRR34280936_k127_852714_235
acyl carrier protein
-
-
-
0.0000000000000000000000000000000002305
132.0
SRR34280936_k127_852714_237
Belongs to the BolA IbaG family
-
-
-
0.0000000000000000000000000000000003096
134.0
SRR34280936_k127_852714_238
Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K03642
-
-
0.0000000000000000000000000000000005208
139.0
SRR34280936_k127_852714_239
Integral membrane protein CcmA involved in cell shape determination
-
-
-
0.0000000000000000000000000000000005617
138.0
SRR34280936_k127_852714_24
Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
K00626
-
2.3.1.9
4.459e-228
709.0
SRR34280936_k127_852714_240
PFAM export protein FliQ family 3
K02420
-
-
0.00000000000000000000000000000003871
128.0
SRR34280936_k127_852714_241
Putative diguanylate phosphodiesterase
-
-
-
0.000000000000000000000000000000103
138.0
SRR34280936_k127_852714_242
-
-
-
-
0.0000000000000000000000000000003771
124.0
SRR34280936_k127_852714_243
Uncharacterized conserved protein (DUF2285)
-
-
-
0.000000000000000000000000000009062
120.0
SRR34280936_k127_852714_244
Belongs to the bacterial ribosomal protein bL33 family
K02913
-
-
0.0000000000000000000000000004485
113.0
SRR34280936_k127_852714_245
Cold-shock protein
K03704
-
-
0.000000000000000000000000001016
113.0
SRR34280936_k127_852714_246
acyl carrier protein
-
-
-
0.000000000000000000000000002801
113.0
SRR34280936_k127_852714_247
integral membrane protein
K02221
-
-
0.000000000000000000000000004672
113.0
SRR34280936_k127_852714_248
-
-
-
-
0.00000000000000000000000001333
120.0
SRR34280936_k127_852714_249
Flagellar hook capping protein - N-terminal region
K02389
-
-
0.00000000000000000000000002834
112.0
SRR34280936_k127_852714_25
transfer protein trbL
K07344
-
-
1.52e-220
690.0
SRR34280936_k127_852714_250
HicA toxin of bacterial toxin-antitoxin,
-
-
-
0.000000000000000000000000234
106.0
SRR34280936_k127_852714_251
conserved small protein
-
-
-
0.000000000000000000000000803
108.0
SRR34280936_k127_852714_252
FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
-
-
-
1.406e-219
692.0
SRR34280936_k127_852714_260
Flagellar biogenesis protein
K02418
-
-
0.00000000000000000006662
98.0
SRR34280936_k127_852714_262
-
-
-
-
0.0000000000000000002913
93.0
SRR34280936_k127_852714_264
-
-
-
-
0.000000000000000003016
86.0
SRR34280936_k127_852714_265
SpoVT / AbrB like domain
-
-
-
0.000000000000000003513
86.0
SRR34280936_k127_852714_266
Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation
K03073
-
-
0.000000000000000005932
89.0
SRR34280936_k127_852714_267
-
-
-
-
0.000000000000000008668
98.0
SRR34280936_k127_852714_268
Rod binding protein
K02395
-
-
0.000000000000000009071
86.0
SRR34280936_k127_852714_269
-
-
-
-
0.0000000000000000721
82.0
SRR34280936_k127_852714_27
AAA domain, putative AbiEii toxin, Type IV TA system
-
-
-
5.658e-216
684.0
SRR34280936_k127_852714_270
Flagellar assembly protein fliH
K02411
-
-
0.0000000000000007256
87.0
SRR34280936_k127_852714_272
-
-
-
-
0.00000000000002016
80.0
SRR34280936_k127_852714_273
helix_turn_helix, Lux Regulon
-
-
-
0.00000000000009811
77.0
SRR34280936_k127_852714_274
Protein of unknown function (DUF2490)
-
-
-
0.0000000000001283
79.0
SRR34280936_k127_852714_275
Flagellar protein FliS
K02422
-
-
0.000000000001861
72.0
SRR34280936_k127_852714_276
Protein of unknown function (DUF1674)
-
-
-
0.000000000002363
78.0
SRR34280936_k127_852714_277
-
-
-
-
0.000000000008395
74.0
SRR34280936_k127_852714_278
Uncharacterized small protein (DUF2292)
-
-
-
0.00000000001836
68.0
SRR34280936_k127_852714_279
CAAX protease self-immunity
K07052
-
-
0.00000000004058
72.0
SRR34280936_k127_852714_28
Type IV secretory pathway VirD2
-
-
-
6.29e-216
687.0
SRR34280936_k127_852714_280
domain protein
K20276
-
-
0.000000000233
74.0
SRR34280936_k127_852714_281
PFAM Sel1 domain protein repeat-containing protein
K07126
-
-
0.0000000002553
71.0
SRR34280936_k127_852714_282
response regulator
-
-
-
0.000000002
64.0
SRR34280936_k127_852714_283
-
-
-
-
0.000000002705
58.0
SRR34280936_k127_852714_284
4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process
-
-
-
0.000000002863
69.0
SRR34280936_k127_852714_285
-
-
-
-
0.00000001063
63.0
SRR34280936_k127_852714_286
-
-
-
-
0.00000001954
64.0
SRR34280936_k127_852714_287
flagellar motor switch protein
K02416
-
-
0.00000004688
64.0
SRR34280936_k127_852714_288
-
-
-
-
0.000000095
59.0
SRR34280936_k127_852714_29
Acts as a magnesium transporter
K06213
-
-
8.706e-212
666.0
SRR34280936_k127_852714_290
bacterial-type flagellum assembly
-
-
-
0.0000005365
61.0
SRR34280936_k127_852714_292
Belongs to the flagella basal body rod proteins family
K02388
-
-
0.00002072
49.0
SRR34280936_k127_852714_293
-
-
-
-
0.00002234
57.0
SRR34280936_k127_852714_294
-
-
-
-
0.00006608
51.0
SRR34280936_k127_852714_295
-
-
-
-
0.0004795
46.0
SRR34280936_k127_852714_296
-
-
-
-
0.000514
53.0
SRR34280936_k127_852714_297
Anti-sigma-28 factor, FlgM
K02398
-
-
0.0006363
46.0
SRR34280936_k127_852714_298
-
-
-
-
0.0008007
44.0
SRR34280936_k127_852714_3
C-terminal domain on Strawberry notch homologue
-
-
-
0.0
1910.0
SRR34280936_k127_852714_30
belongs to the aldehyde dehydrogenase family
K00135
-
1.2.1.16,1.2.1.20,1.2.1.79
2.489e-211
666.0
SRR34280936_k127_852714_31
Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine
Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Belongs to the bacterial ribosomal protein bL36 family
K02919
-
-
0.000000000000001355
80.0
SRR34280936_k127_923601_1001
Polysaccharide biosynthesis protein
-
-
-
0.000000000000002253
89.0
SRR34280936_k127_923601_1002
-
-
-
-
0.000000000000006837
76.0
SRR34280936_k127_923601_1003
ParE toxin of type II toxin-antitoxin system, parDE
-
-
-
0.00000000000001436
77.0
SRR34280936_k127_923601_1004
SpoIIAA-like
-
-
-
0.0000000000000666
77.0
SRR34280936_k127_923601_1005
Transposase and inactivated
K07492
-
-
0.00000000000006845
74.0
SRR34280936_k127_923601_1006
Staphylococcal nuclease homologues
-
-
-
0.00000000000007136
80.0
SRR34280936_k127_923601_1007
-
-
-
-
0.000000000000094
74.0
SRR34280936_k127_923601_1008
-
-
-
-
0.0000000000001071
73.0
SRR34280936_k127_923601_1009
Flp/Fap pilin component
K02651
-
-
0.0000000000001122
73.0
SRR34280936_k127_923601_101
single-stranded-DNA-specific exonuclease RecJ
K07462
-
-
6.258e-259
811.0
SRR34280936_k127_923601_1010
-
-
-
-
0.0000000000001184
78.0
SRR34280936_k127_923601_1012
-
-
-
-
0.0000000000005101
76.0
SRR34280936_k127_923601_1013
-
-
-
-
0.0000000000005821
76.0
SRR34280936_k127_923601_1014
-
-
-
-
0.000000000004832
71.0
SRR34280936_k127_923601_1015
Flp/Fap pilin component
K02651
-
-
0.000000000006631
68.0
SRR34280936_k127_923601_1016
-
-
-
-
0.00000000001074
70.0
SRR34280936_k127_923601_1017
-
-
-
-
0.00000000001457
71.0
SRR34280936_k127_923601_1019
COG3209 Rhs family protein
-
-
-
0.00000000002273
66.0
SRR34280936_k127_923601_102
Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K03688
-
-
2.078e-258
803.0
SRR34280936_k127_923601_1020
-
-
-
-
0.00000000006575
68.0
SRR34280936_k127_923601_1021
-
-
-
-
0.00000000007909
69.0
SRR34280936_k127_923601_1022
Heat shock protein DnaJ domain protein
-
-
-
0.0000000001237
69.0
SRR34280936_k127_923601_1023
SnoaL-like domain
-
-
-
0.000000000244
70.0
SRR34280936_k127_923601_1026
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex
K09699
-
2.3.1.168
0.0000000098
58.0
SRR34280936_k127_923601_1027
Resolvase
-
-
-
0.00000001501
58.0
SRR34280936_k127_923601_1028
-
-
-
-
0.00000003162
65.0
SRR34280936_k127_923601_103
Penicillin-binding Protein
K05515
-
3.4.16.4
1.245e-257
811.0
SRR34280936_k127_923601_1030
-
-
-
-
0.00000007497
59.0
SRR34280936_k127_923601_1033
-
-
-
-
0.0000002918
57.0
SRR34280936_k127_923601_1034
PilZ domain
-
-
-
0.0000003835
57.0
SRR34280936_k127_923601_1035
amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
K01873
-
6.1.1.9
0.0000007937
54.0
SRR34280936_k127_923601_1037
-
-
-
-
0.0000009651
52.0
SRR34280936_k127_923601_1038
-
-
-
-
0.000001171
54.0
SRR34280936_k127_923601_104
belongs to the aldehyde dehydrogenase family
K00128
-
1.2.1.3
3.534e-257
799.0
SRR34280936_k127_923601_1041
Resolvase
-
-
-
0.000001851
52.0
SRR34280936_k127_923601_1044
Membrane-bound lysozyme-inhibitor of c-type lysozyme
-
-
-
0.000002167
58.0
SRR34280936_k127_923601_1045
small protein
-
-
-
0.000003452
52.0
SRR34280936_k127_923601_1047
Type II secretion system (T2SS), protein G
K02456
-
-
0.000006373
49.0
SRR34280936_k127_923601_1049
-
-
-
-
0.0000102
49.0
SRR34280936_k127_923601_105
Belongs to the aldehyde dehydrogenase family
K00154
-
1.2.1.68
5.044e-257
800.0
SRR34280936_k127_923601_1050
Belongs to the UPF0235 family
K09131
-
-
0.00001225
51.0
SRR34280936_k127_923601_1051
-
-
-
-
0.00008068
48.0
SRR34280936_k127_923601_1053
TonB dependent receptor
-
-
-
0.00009764
46.0
SRR34280936_k127_923601_1057
Tetratricopeptide repeat
-
-
-
0.0002364
52.0
SRR34280936_k127_923601_106
partitioning protein, ParB
K03497
-
-
3.54e-255
804.0
SRR34280936_k127_923601_1060
Belongs to the class-I aminoacyl-tRNA synthetase family
K01883
-
6.1.1.16
0.0004857
43.0
SRR34280936_k127_923601_1063
Alpha beta hydrolase
-
-
-
0.0009153
44.0
SRR34280936_k127_923601_107
Type-1V conjugative transfer system mating pair stabilisation
K12058
-
-
4.903e-255
799.0
SRR34280936_k127_923601_108
Belongs to the argininosuccinate synthase family. Type 1 subfamily
K01940
-
6.3.4.5
1.052e-253
784.0
SRR34280936_k127_923601_109
acyl-CoA dehydrogenase
-
-
-
1.289e-253
783.0
SRR34280936_k127_923601_11
amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K01870
-
6.1.1.5
0.0
1419.0
SRR34280936_k127_923601_110
Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K00036
-
1.1.1.363,1.1.1.49
6.604e-252
782.0
SRR34280936_k127_923601_111
DNA helicase
K03654
-
3.6.4.12
1.632e-250
786.0
SRR34280936_k127_923601_112
Polysaccharide biosynthesis protein CapD
-
-
-
1.65e-248
782.0
SRR34280936_k127_923601_113
Ammonium Transporter
K03320
-
-
6.3e-247
769.0
SRR34280936_k127_923601_114
Gamma-glutamyltranspeptidase
K00681
-
2.3.2.2,3.4.19.13
7.439e-247
775.0
SRR34280936_k127_923601_115
protein involved in exopolysaccharide biosynthesis
K16554
-
-
9.98e-247
781.0
SRR34280936_k127_923601_116
Aminotransferase
K14261
-
-
8.301e-246
762.0
SRR34280936_k127_923601_117
Amidohydrolase family
-
-
-
1.733e-244
766.0
SRR34280936_k127_923601_118
Belongs to the DEAD box helicase family
K05592
-
3.6.4.13
4.722e-243
764.0
SRR34280936_k127_923601_119
acetylornithine aminotransferase
K00821
-
2.6.1.11,2.6.1.17
1.934e-241
748.0
SRR34280936_k127_923601_12
DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase
K14162
-
2.7.7.7
0.0
1419.0
SRR34280936_k127_923601_120
protein conserved in bacteria
-
-
-
4.893e-241
757.0
SRR34280936_k127_923601_121
Belongs to the MurCDEF family
K01924
-
6.3.2.8
3.567e-240
750.0
SRR34280936_k127_923601_122
beta-1,4-mannooligosaccharide phosphorylase
-
-
-
3.857e-238
741.0
SRR34280936_k127_923601_123
Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
K00626
-
2.3.1.9
1.055e-236
735.0
SRR34280936_k127_923601_124
phosphomannomutase
K01840
-
5.4.2.8
4.965e-236
736.0
SRR34280936_k127_923601_125
Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit
K01903
-
6.2.1.5
3.371e-235
731.0
SRR34280936_k127_923601_126
acyl-CoA dehydrogenase
K00249
-
1.3.8.7
1.365e-234
727.0
SRR34280936_k127_923601_127
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K00412
-
-
1.505e-234
730.0
SRR34280936_k127_923601_128
receptor
-
-
-
5.213e-233
745.0
SRR34280936_k127_923601_129
it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins
K02314
-
3.6.4.12
8.865e-233
731.0
SRR34280936_k127_923601_13
TraG-like protein, N-terminal region
K12056
-
-
0.0
1416.0
SRR34280936_k127_923601_130
Bacterial protein of unknown function (DUF853)
K06915
-
-
4.424e-232
728.0
SRR34280936_k127_923601_131
The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
K00282
-
1.4.4.2
3.29e-231
723.0
SRR34280936_k127_923601_132
Belongs to the GMC oxidoreductase family
-
-
-
5.155e-231
725.0
SRR34280936_k127_923601_133
Belongs to the class-I aminoacyl-tRNA synthetase family
K01883
-
6.1.1.16
6.152e-231
722.0
SRR34280936_k127_923601_134
Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
K06941
-
2.1.1.192
2.97e-230
717.0
SRR34280936_k127_923601_135
acyl-CoA dehydrogenase
K00252
-
1.3.8.6
3.338e-230
715.0
SRR34280936_k127_923601_136
poly(R)-hydroxyalkanoic acid synthase
K03821
-
-
6.737e-230
723.0
SRR34280936_k127_923601_137
Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K00790
-
2.5.1.7
4.038e-229
714.0
SRR34280936_k127_923601_138
Belongs to the pyruvate kinase family
K00873
-
2.7.1.40
5.826e-229
726.0
SRR34280936_k127_923601_139
AMP-binding enzyme C-terminal domain
K00666
-
-
1.052e-228
718.0
SRR34280936_k127_923601_14
COG2931, RTX toxins and related Ca2 -binding proteins
-
-
-
0.0
1416.0
SRR34280936_k127_923601_140
Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)
K14986
-
2.7.13.3
2.506e-227
715.0
SRR34280936_k127_923601_141
transport
-
-
-
1.033e-226
731.0
SRR34280936_k127_923601_142
Belongs to the aspartokinase family
K00928
-
2.7.2.4
4.315e-226
706.0
SRR34280936_k127_923601_143
Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K04042
-
2.3.1.157,2.7.7.23
9.177e-225
703.0
SRR34280936_k127_923601_144
Cell division protein FtsI penicillin-binding protein
K03587
-
3.4.16.4
1.454e-224
709.0
SRR34280936_k127_923601_145
Type II/IV secretion system protein
K02283
-
-
2.336e-224
703.0
SRR34280936_k127_923601_146
Ring hydroxylating alpha subunit (catalytic domain)
-
-
-
4.395e-223
697.0
SRR34280936_k127_923601_147
Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K02472
-
1.1.1.336
2.099e-221
692.0
SRR34280936_k127_923601_148
GTPase that plays an essential role in the late steps of ribosome biogenesis
K03977
-
-
2.87e-221
693.0
SRR34280936_k127_923601_149
amidohydrolase
-
-
-
1.514e-220
689.0
SRR34280936_k127_923601_15
Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
-
-
-
0.0
1372.0
SRR34280936_k127_923601_150
Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide
K01739,K10764
-
2.5.1.48
5.126e-220
694.0
SRR34280936_k127_923601_151
ATPase related to the helicase subunit of the Holliday junction resolvase
K07478
-
-
7.916e-219
686.0
SRR34280936_k127_923601_152
Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K00012
-
1.1.1.22
1.473e-217
682.0
SRR34280936_k127_923601_153
Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
K03980
-
-
1.486e-217
686.0
SRR34280936_k127_923601_154
acyl-CoA dehydrogenase
K00249
-
1.3.8.7
1.85e-217
680.0
SRR34280936_k127_923601_155
acyl-CoA dehydrogenase
K00255
-
1.3.8.8
2.629e-217
678.0
SRR34280936_k127_923601_156
flavoprotein involved in K transport
-
-
-
6.129e-217
685.0
SRR34280936_k127_923601_157
Trypsin-like peptidase domain
-
-
-
6.358e-217
676.0
SRR34280936_k127_923601_158
COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes
K11159,K21822
-
1.13.11.82
2.553e-216
680.0
SRR34280936_k127_923601_159
Threonine synthase
K01733
-
4.2.3.1
5.883e-215
677.0
SRR34280936_k127_923601_16
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K02470
-
5.99.1.3
0.0
1356.0
SRR34280936_k127_923601_160
DNA recombination-mediator protein A
-
-
-
6.624e-215
668.0
SRR34280936_k127_923601_161
Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate
K01679
-
4.2.1.2
1.88e-214
676.0
SRR34280936_k127_923601_162
Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit
K01426
-
3.5.1.4
1.187e-213
675.0
SRR34280936_k127_923601_163
Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K01928
-
6.3.2.13
9.085e-213
670.0
SRR34280936_k127_923601_164
COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases
K00528
-
1.18.1.2,1.19.1.1
1.126e-212
667.0
SRR34280936_k127_923601_165
AMP-binding enzyme C-terminal domain
-
-
-
2.4e-212
673.0
SRR34280936_k127_923601_166
Acyl-CoA dehydrogenase, middle domain
-
-
-
8.818e-211
660.0
SRR34280936_k127_923601_167
Acyl-CoA dehydrogenase, C-terminal domain
-
-
-
1.132e-208
655.0
SRR34280936_k127_923601_168
Belongs to the DEAD box helicase family
-
-
-
1.984e-208
657.0
SRR34280936_k127_923601_169
Involved in the TonB-independent uptake of proteins
K03641
-
-
2.279e-208
658.0
SRR34280936_k127_923601_17
Belongs to the class-I aminoacyl-tRNA synthetase family
K01869
-
6.1.1.4
0.0
1332.0
SRR34280936_k127_923601_170
COG1760 L-serine deaminase
K01752
-
4.3.1.17
2.293e-208
656.0
SRR34280936_k127_923601_171
-
-
-
-
2.794e-208
657.0
SRR34280936_k127_923601_172
Aldehyde dehydrogenase family
K00128
-
1.2.1.3
3.511e-208
658.0
SRR34280936_k127_923601_173
Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)
K00773
-
2.4.2.29
1.751e-207
649.0
SRR34280936_k127_923601_174
Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K03531
-
-
5.342e-207
654.0
SRR34280936_k127_923601_175
it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K02313
-
-
1.092e-206
651.0
SRR34280936_k127_923601_176
protein-S-isoprenylcysteine methyltransferase
-
-
-
1.128e-206
653.0
SRR34280936_k127_923601_177
Alkyl sulfatase dimerisation
-
-
-
3.429e-206
659.0
SRR34280936_k127_923601_178
Acyl-CoA dehydrogenase, middle domain
-
-
-
5.092e-206
654.0
SRR34280936_k127_923601_179
Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation
K00626
-
2.3.1.9
2.715e-205
645.0
SRR34280936_k127_923601_18
Nitric oxide reductase
K04561
-
1.7.2.5
0.0
1296.0
SRR34280936_k127_923601_180
Conjugal transfer protein
K12060
-
-
6.093e-205
642.0
SRR34280936_k127_923601_181
Sodium/hydrogen exchanger family
-
-
-
4.342e-203
639.0
SRR34280936_k127_923601_182
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate
K00800
-
2.5.1.19
5.893e-203
640.0
SRR34280936_k127_923601_183
Bacterial conjugation TrbI-like protein
K12065
-
-
8.579e-202
637.0
SRR34280936_k127_923601_184
Aminoglycoside phosphotransferase
-
-
-
2.15e-201
630.0
SRR34280936_k127_923601_185
Polysaccharide biosynthesis protein
-
-
-
4.586e-201
638.0
SRR34280936_k127_923601_186
Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K06168
-
2.8.4.3
1.792e-200
632.0
SRR34280936_k127_923601_187
amino acid
K03294
-
-
3.148e-200
637.0
SRR34280936_k127_923601_188
Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K14652
-
3.5.4.25,4.1.99.12
4.851e-200
630.0
SRR34280936_k127_923601_189
alcohol dehydrogenase
K00121
-
1.1.1.1,1.1.1.284
6.707e-200
632.0
SRR34280936_k127_923601_19
damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage
K03702
-
-
0.0
1293.0
SRR34280936_k127_923601_190
Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K00790
-
2.5.1.7
1.04e-199
629.0
SRR34280936_k127_923601_191
rod shape-determining protein MreB
K03569
-
-
1.324e-199
624.0
SRR34280936_k127_923601_192
belongs to the aldehyde dehydrogenase family
K22187
-
-
2.905e-199
631.0
SRR34280936_k127_923601_193
cytochrome P450
-
-
-
9.329e-199
627.0
SRR34280936_k127_923601_194
peptidase M20
K01295
-
3.4.17.11
7.969e-198
625.0
SRR34280936_k127_923601_195
UDP-N-acetylglucosamine 2-epimerase
K01791
-
5.1.3.14
7.748e-197
618.0
SRR34280936_k127_923601_196
amidohydrolase
-
-
-
1.077e-196
622.0
SRR34280936_k127_923601_197
Threonine dehydratase
K01754
-
4.3.1.19
1.113e-196
619.0
SRR34280936_k127_923601_198
Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria
K02338
-
2.7.7.7
2.392e-196
617.0
SRR34280936_k127_923601_199
metal-dependent hydrolase with the TIM-barrel fold
-
-
-
1.427e-195
626.0
SRR34280936_k127_923601_2
The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate
K03701
-
-
0.0
1688.0
SRR34280936_k127_923601_20
TonB dependent receptor
-
-
-
0.0
1247.0
SRR34280936_k127_923601_200
4-hydroxyphenylpyruvate dioxygenase
K00457
-
1.13.11.27
2.521e-195
617.0
SRR34280936_k127_923601_201
Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing
Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate
Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule
Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Oxidizes proline to glutamate for use as a carbon and nitrogen source
K13821
-
1.2.1.88,1.5.5.2
0.0
1118.0
SRR34280936_k127_923601_320
Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate
Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group
Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety
Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2)
Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner
Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)
NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE
K03695
-
-
0.0
1467.0
SRR34280936_k127_923601_40
COG1629 Outer membrane receptor proteins, mostly Fe transport
Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates
Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides
Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit
Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane
COG1629 Outer membrane receptor proteins, mostly Fe transport
-
-
-
0.0
1461.0
SRR34280936_k127_923601_50
Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
COG1629 Outer membrane receptor proteins, mostly Fe transport
-
-
-
0.0
1451.0
SRR34280936_k127_923601_60
COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II
K00666
-
-
1.14e-307
950.0
SRR34280936_k127_923601_600
Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine
Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K01895
-
6.2.1.1
1.099e-302
939.0
SRR34280936_k127_923601_620
Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex
Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin
Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB
amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner
K01873
-
6.1.1.9
0.0
1438.0
SRR34280936_k127_923601_70
Thi4 family
-
-
-
1.591e-286
886.0
SRR34280936_k127_923601_700
Chaperone required for the assembly of the mitochondrial F1-ATPase
One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA
Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein
Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism
Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits
RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme
Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K04078
-
-
0.00000000000000000000000000000000000000000001249
163.0
SRR34280936_k127_923601_835
SnoaL-like domain
-
-
-
0.00000000000000000000000000000000000000000001294
172.0
SRR34280936_k127_923601_836
Protein of unknown function (DUF559)
-
-
-
0.00000000000000000000000000000000000000000001602
167.0
SRR34280936_k127_923601_837
Transcriptional regulator
-
-
-
0.00000000000000000000000000000000000000000002167
164.0
SRR34280936_k127_923601_838
transferase activity, transferring glycosyl groups
-
-
-
0.00000000000000000000000000000000000000000003279
177.0
SRR34280936_k127_923601_839
-
-
-
-
0.00000000000000000000000000000000000000000003758
164.0
SRR34280936_k127_923601_84
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase
K06147
-
-
1.283e-274
856.0
SRR34280936_k127_923601_840
Protein of unknown function (DUF983)
-
-
-
0.00000000000000000000000000000000000000000004115
164.0
SRR34280936_k127_923601_841
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis
K01489
-
3.5.4.5
0.00000000000000000000000000000000000000000004277
164.0
SRR34280936_k127_923601_842
-
-
-
-
0.00000000000000000000000000000000000000000005769
160.0
SRR34280936_k127_923601_843
Bacterial regulatory proteins, tetR family
-
-
-
0.00000000000000000000000000000000000000000008161
166.0
SRR34280936_k127_923601_844
SnoaL-like domain
-
-
-
0.0000000000000000000000000000000000000000002261
162.0
SRR34280936_k127_923601_845
Belongs to the HesB IscA family
-
-
-
0.0000000000000000000000000000000000000000002917
160.0
SRR34280936_k127_923601_846
Belongs to the Nudix hydrolase family
K03574
-
3.6.1.55
0.0000000000000000000000000000000000000000007286
163.0
SRR34280936_k127_923601_847
Hpt domain
K20976
-
-
0.0000000000000000000000000000000000000000009653
160.0
SRR34280936_k127_923601_848
Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
K03832
-
-
0.000000000000000000000000000000000000000001622
164.0
SRR34280936_k127_923601_849
Putative transposase of IS4/5 family (DUF4096)
-
-
-
0.000000000000000000000000000000000000000001792
158.0
SRR34280936_k127_923601_85
-
-
-
-
4.033e-273
854.0
SRR34280936_k127_923601_850
PIN domain
-
-
-
0.00000000000000000000000000000000000000000327
158.0
SRR34280936_k127_923601_851
Arsenate reductase
K00537
-
1.20.4.1
0.000000000000000000000000000000000000000004003
161.0
SRR34280936_k127_923601_852
Transglycosylase associated protein
-
-
-
0.00000000000000000000000000000000000000001561
154.0
SRR34280936_k127_923601_853
cheY-homologous receiver domain
-
-
-
0.00000000000000000000000000000000000000002587
158.0
SRR34280936_k127_923601_854
YoeB-like toxin of bacterial type II toxin-antitoxin system
K19158
-
-
0.00000000000000000000000000000000000000006243
156.0
SRR34280936_k127_923601_855
Protein of unknown function (FYDLN_acid)
-
-
-
0.00000000000000000000000000000000000000008242
153.0
SRR34280936_k127_923601_856
protein, possibly involved in aromatic compounds catabolism
-
-
-
0.0000000000000000000000000000000000000001413
154.0
SRR34280936_k127_923601_857
Uroporphyrinogen-III synthase
K01719
-
4.2.1.75
0.0000000000000000000000000000000000000001726
164.0
SRR34280936_k127_923601_858
protein involved in cysteine biosynthesis
K06203
-
-
0.000000000000000000000000000000000000000337
163.0
SRR34280936_k127_923601_859
peptidase
K02278
-
3.4.23.43
0.0000000000000000000000000000000000000004138
153.0
SRR34280936_k127_923601_86
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K03572
-
-
5.092e-271
844.0
SRR34280936_k127_923601_860
Bacterial PH domain
K09167
-
-
0.0000000000000000000000000000000000000007906
154.0
SRR34280936_k127_923601_861
MerC mercury resistance protein
-
-
-
0.000000000000000000000000000000000000001192
151.0
SRR34280936_k127_923601_862
invasion associated locus B
-
-
-
0.000000000000000000000000000000000000001374
152.0
SRR34280936_k127_923601_863
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K07042
-
-
0.000000000000000000000000000000000000001392
154.0
SRR34280936_k127_923601_864
Could be involved in insertion of integral membrane proteins into the membrane
K08998
-
-
0.000000000000000000000000000000000000002185
147.0
SRR34280936_k127_923601_865
ribonuclease E activity
-
-
-
0.000000000000000000000000000000000000002212
161.0
SRR34280936_k127_923601_866
Thiamine monophosphate synthase
K00788
-
2.5.1.3
0.000000000000000000000000000000000000002297
156.0
SRR34280936_k127_923601_867
Phasin protein
-
-
-
0.000000000000000000000000000000000000002734
154.0
SRR34280936_k127_923601_868
COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases
-
-
-
0.000000000000000000000000000000000000003025
156.0
SRR34280936_k127_923601_869
TadE-like protein
-
-
-
0.000000000000000000000000000000000000003847
151.0
SRR34280936_k127_923601_87
competence protein
-
-
-
3.162e-268
826.0
SRR34280936_k127_923601_870
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control
K05788
-
-
0.000000000000000000000000000000000000004341
150.0
SRR34280936_k127_923601_871
-
-
-
-
0.00000000000000000000000000000000000000751
152.0
SRR34280936_k127_923601_872
-
-
-
-
0.000000000000000000000000000000000000008764
148.0
SRR34280936_k127_923601_873
-
-
-
-
0.00000000000000000000000000000000000001044
153.0
SRR34280936_k127_923601_874
-
-
-
-
0.00000000000000000000000000000000000001202
148.0
SRR34280936_k127_923601_875
-
-
-
-
0.00000000000000000000000000000000000002476
146.0
SRR34280936_k127_923601_876
OsmC-like protein
K06889,K07397
-
-
0.00000000000000000000000000000000000004583
148.0
SRR34280936_k127_923601_877
-
-
-
-
0.00000000000000000000000000000000000006516
149.0
SRR34280936_k127_923601_878
One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K02518
-
-
0.0000000000000000000000000000000000001748
141.0
SRR34280936_k127_923601_879
-
-
-
-
0.0000000000000000000000000000000000002425
142.0
SRR34280936_k127_923601_88
penicillin-binding protein
K05366
-
2.4.1.129,3.4.16.4
3.211e-268
842.0
SRR34280936_k127_923601_880
-acetyltransferase
-
-
-
0.0000000000000000000000000000000000003008
147.0
SRR34280936_k127_923601_881
-
-
-
-
0.0000000000000000000000000000000000003563
150.0
SRR34280936_k127_923601_882
helix_turn_helix, mercury resistance
-
-
-
0.0000000000000000000000000000000000004619
145.0
SRR34280936_k127_923601_883
-
-
-
-
0.0000000000000000000000000000000000004619
145.0
SRR34280936_k127_923601_884
Glycine zipper 2TM domain
-
-
-
0.0000000000000000000000000000000000004707
144.0
SRR34280936_k127_923601_886
-
-
-
-
0.0000000000000000000000000000000000008337
151.0
SRR34280936_k127_923601_887
protein conserved in bacteria
-
-
-
0.000000000000000000000000000000000001571
149.0
SRR34280936_k127_923601_888
GtrA-like protein
-
-
-
0.000000000000000000000000000000000003301
146.0
SRR34280936_k127_923601_889
Protein of unknown function (DUF3297)
-
-
-
0.000000000000000000000000000000000003505
139.0
SRR34280936_k127_923601_89
COG1629 Outer membrane receptor proteins, mostly Fe transport
K02014
-
-
4.797e-268
842.0
SRR34280936_k127_923601_890
enzyme involved in biosynthesis of extracellular polysaccharides
-
-
-
0.00000000000000000000000000000000001314
138.0
SRR34280936_k127_923601_891
FOG TPR repeat, SEL1 subfamily
K07126
-
-
0.00000000000000000000000000000000001788
139.0
SRR34280936_k127_923601_892
2',5' RNA ligase
K01975
-
3.1.4.58
0.00000000000000000000000000000000004223
140.0
SRR34280936_k127_923601_893
-
-
-
-
0.00000000000000000000000000000000004237
140.0
SRR34280936_k127_923601_894
Type-F conjugative transfer system protein (TrbI_Ftype)
-
-
-
0.0000000000000000000000000000000000549
138.0
SRR34280936_k127_923601_895
Binds directly to 16S ribosomal RNA
K02968
-
-
0.00000000000000000000000000000000005871
135.0
SRR34280936_k127_923601_896
PD-(D/E)XK nuclease superfamily
-
-
-
0.0000000000000000000000000000000001042
136.0
SRR34280936_k127_923601_897
-
-
-
-
0.0000000000000000000000000000000001204
140.0
SRR34280936_k127_923601_898
diguanylate cyclase
-
-
-
0.0000000000000000000000000000000001373
140.0
SRR34280936_k127_923601_899
helix_turn_helix, Lux Regulon
-
-
-
0.0000000000000000000000000000000003835
136.0
SRR34280936_k127_923601_9
COG3451 Type IV secretory pathway, VirB4 components
K12063
-
-
0.0
1422.0
SRR34280936_k127_923601_90
Catalyzes the oxidation of L-aspartate to iminoaspartate
K00278
-
1.4.3.16
1.444e-267
831.0
SRR34280936_k127_923601_900
-
-
-
-
0.0000000000000000000000000000000003968
137.0
SRR34280936_k127_923601_901
-
-
-
-
0.000000000000000000000000000000000609
133.0
SRR34280936_k127_923601_902
EF-hand, calcium binding motif
-
-
-
0.000000000000000000000000000000000679
138.0
SRR34280936_k127_923601_903
Cyclic nucleotide-monophosphate binding domain
-
-
-
0.0000000000000000000000000000000008484
139.0
SRR34280936_k127_923601_904
protein conserved in bacteria
K09948
-
-
0.000000000000000000000000000000001014
145.0
SRR34280936_k127_923601_905
Cytochrome C oxidase, cbb3-type, subunit III
-
-
-
0.000000000000000000000000000000001449
136.0
SRR34280936_k127_923601_906
Predicted integral membrane protein (DUF2282)
-
-
-
0.000000000000000000000000000000002944
133.0
SRR34280936_k127_923601_907
Methyltransferase domain
-
-
-
0.00000000000000000000000000000000412
138.0
SRR34280936_k127_923601_908
Belongs to the UPF0335 family
-
-
-
0.000000000000000000000000000000008185
129.0
SRR34280936_k127_923601_909
-
-
-
-
0.000000000000000000000000000000009914
135.0
SRR34280936_k127_923601_91
Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
-
-
-
2.993e-267
842.0
SRR34280936_k127_923601_910
Phosphoribosyl-ATP
K01523
-
3.6.1.31
0.00000000000000000000000000000001048
130.0
SRR34280936_k127_923601_911
Protein of unknown function (DUF1465)
K13592
-
-
0.00000000000000000000000000000002066
131.0
SRR34280936_k127_923601_912
-
-
-
-
0.00000000000000000000000000000002163
139.0
SRR34280936_k127_923601_913
-
-
-
-
0.00000000000000000000000000000003984
141.0
SRR34280936_k127_923601_914
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation
K03117
-
-
0.00000000000000000000000000000004441
128.0
SRR34280936_k127_923601_915
Excalibur calcium-binding domain
-
-
-
0.000000000000000000000000000000164
126.0
SRR34280936_k127_923601_916
-
-
-
-
0.0000000000000000000000000000002093
127.0
SRR34280936_k127_923601_917
helix_turn_helix, arabinose operon control protein
-
-
-
0.0000000000000000000000000000004221
132.0
SRR34280936_k127_923601_918
Antitoxin component of a toxin-antitoxin (TA) module
K19159
-
-
0.0000000000000000000000000000005352
129.0
SRR34280936_k127_923601_919
Domain of unknown function (DUF4402)
-
-
-
0.0000000000000000000000000000006364
128.0
SRR34280936_k127_923601_92
signal transduction protein containing a membrane domain, an EAL and a GGDEF domain
-
-
-
3.351e-267
843.0
SRR34280936_k127_923601_920
-
-
-
-
0.0000000000000000000000000000006507
126.0
SRR34280936_k127_923601_921
Thioesterase superfamily
K07107
-
-
0.000000000000000000000000000001229
129.0
SRR34280936_k127_923601_922
-
-
-
-
0.000000000000000000000000000001558
121.0
SRR34280936_k127_923601_923
LytTr DNA-binding domain
-
-
-
0.000000000000000000000000000002426
131.0
SRR34280936_k127_923601_924
Pilus assembly protein PilZ
-
-
-
0.00000000000000000000000000000368
123.0
SRR34280936_k127_923601_926
Acetyltransferase
K03789
-
2.3.1.128
0.000000000000000000000000000009213
130.0
SRR34280936_k127_923601_927
Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K06199
-
-
0.00000000000000000000000000001263
122.0
SRR34280936_k127_923601_928
protein, possibly involved in aromatic compounds catabolism
K02614
-
-
0.00000000000000000000000000001617
121.0
SRR34280936_k127_923601_929
Transcriptional regulator
K07729
-
-
0.00000000000000000000000000002467
120.0
SRR34280936_k127_923601_93
Transketolase, pyrimidine binding domain
K11381
-
1.2.4.4
9.193e-266
839.0
SRR34280936_k127_923601_930
-
-
-
-
0.00000000000000000000000000002985
124.0
SRR34280936_k127_923601_931
TIGRFAM conserved repeat domain
-
-
-
0.00000000000000000000000000003942
124.0
SRR34280936_k127_923601_932
Invasion gene expression up-regulator, SirB
-
-
-
0.00000000000000000000000000005242
120.0
SRR34280936_k127_923601_933
Protein of unknown function (DUF2721)
-
-
-
0.00000000000000000000000000005683
125.0
SRR34280936_k127_923601_934
-
-
-
-
0.0000000000000000000000000002204
121.0
SRR34280936_k127_923601_935
Domain of unknown function (DUF4167)
-
-
-
0.0000000000000000000000000002458
125.0
SRR34280936_k127_923601_936
-
-
-
-
0.0000000000000000000000000002815
120.0
SRR34280936_k127_923601_937
Protein of unknown function (DUF3035)
-
-
-
0.0000000000000000000000000003573
121.0
SRR34280936_k127_923601_938
-
-
-
-
0.0000000000000000000000000005052
117.0
SRR34280936_k127_923601_939
protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis
-
-
-
0.0000000000000000000000000006088
115.0
SRR34280936_k127_923601_94
TonB dependent receptor
-
-
-
1.148e-265
837.0
SRR34280936_k127_923601_940
response to heat
K03668,K09914
-
-
0.0000000000000000000000000006875
123.0
SRR34280936_k127_923601_941
PilZ domain
-
-
-
0.000000000000000000000000001017
117.0
SRR34280936_k127_923601_942
Membrane fusogenic activity
K09806
-
-
0.000000000000000000000000001051
115.0
SRR34280936_k127_923601_943
Domain of unknown function (DUF4402)
-
-
-
0.000000000000000000000000001053
121.0
SRR34280936_k127_923601_945
Domain of unknown function (DUF1508)
K09946
-
-
0.000000000000000000000000002452
111.0
SRR34280936_k127_923601_946
nuclease
-
-
-
0.000000000000000000000000003513
117.0
SRR34280936_k127_923601_948
Nickel/cobalt transporter regulator
-
-
-
0.000000000000000000000000005754
121.0
SRR34280936_k127_923601_949
Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH
K07746
-
-
0.000000000000000000000000007313
112.0
SRR34280936_k127_923601_95
phospho-2-dehydro-3-deoxyheptonate aldolase
K01626
-
2.5.1.54
1.375e-264
818.0
SRR34280936_k127_923601_950
Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
Arabinose-binding domain of AraC transcription regulator, N-term
-
-
-
0.0000000000000000000000006261
117.0
SRR34280936_k127_923601_955
Type IV leader peptidase family
K02278
-
3.4.23.43
0.0000000000000000000000006948
110.0
SRR34280936_k127_923601_956
Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system
K03116
-
-
0.000000000000000000000001108
106.0
SRR34280936_k127_923601_957
-
-
-
-
0.00000000000000000000000289
108.0
SRR34280936_k127_923601_958
Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides
K03602
-
3.1.11.6
0.000000000000000000000003579
105.0
SRR34280936_k127_923601_959
RHS Repeat
-
-
-
0.000000000000000000000004062
113.0
SRR34280936_k127_923601_96
peptidase U62, modulator of DNA gyrase
K03568
-
-
3.911e-264
822.0
SRR34280936_k127_923601_961
Uncharacterized protein conserved in bacteria (DUF2093)
-
-
-
0.0000000000000000000000132
102.0
SRR34280936_k127_923601_962
Histidine kinase
-
-
-
0.00000000000000000000001676
116.0
SRR34280936_k127_923601_963
protein conserved in bacteria
-
-
-
0.00000000000000000000003536
100.0
SRR34280936_k127_923601_964
-
-
-
-
0.00000000000000000000006374
104.0
SRR34280936_k127_923601_965
Fe2 transport system protein A
K04758
-
-
0.00000000000000000000007556
102.0
SRR34280936_k127_923601_967
-
-
-
-
0.0000000000000000000001966
103.0
SRR34280936_k127_923601_968
membrane
-
-
-
0.0000000000000000000002165
108.0
SRR34280936_k127_923601_969
-
-
-
-
0.000000000000000000001207
102.0
SRR34280936_k127_923601_97
Metal-dependent hydrolase
-
-
-
8.911e-264
825.0
SRR34280936_k127_923601_971
Antitoxin component of a toxin-antitoxin (TA) module
-
-
-
0.000000000000000000007387
94.0
SRR34280936_k127_923601_972
Prophage CP4-57 regulatory protein (AlpA)
K07733
-
-
0.000000000000000000007392
95.0
SRR34280936_k127_923601_973
Predicted integral membrane protein (DUF2282)
-
-
-
0.00000000000000000002946
97.0
SRR34280936_k127_923601_974
membrane
-
-
-
0.00000000000000000006313
98.0
SRR34280936_k127_923601_975
Protein of unknown function (DUF1622)
-
-
-
0.00000000000000000007686
94.0
SRR34280936_k127_923601_976
-
-
-
-
0.00000000000000000007823
91.0
SRR34280936_k127_923601_977
Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
