## Fri Dec 12 19:34:34 2025
## emapper-2.1.13
## /data/anaconda3/envs/eggnog-mapper/bin/emapper.py -i /data/result/bins/wyx/qs/new/BYD2_bin.40.fa -m mmseqs --itype genome -o BYD2_bin.40 --output_dir /data/result/bins/wyx/egg/BYD2_bin.40 --cpu 32
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
BYD2_k127_1015652_8	1313172.YM304_16550	8.832e-13	75.0	COG3568@1|root,COG3568@2|Bacteria	2|Bacteria	N	Endonuclease Exonuclease Phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_1015652_3	298655.KI912266_gene3054	2.061e-43	168.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
BYD2_k127_1015652_2	1464048.JNZS01000004_gene1436	1.846e-45	178.0	COG3011@1|root,COG3011@2|Bacteria,2IMHW@201174|Actinobacteria,4DEVM@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function, DUF393	-	-	-	-	-	-	-	-	-	-	-	-	DUF393
BYD2_k127_1015652_4	222534.KB893735_gene700	1.022e-42	179.0	COG3505@1|root,COG3505@2|Bacteria,2ISKK@201174|Actinobacteria	201174|Actinobacteria	U	Type IV secretory system Conjugative DNA transfer	-	-	-	ko:K03205	ko03070,map03070	M00333	-	-	ko00000,ko00001,ko00002,ko02044	3.A.7	-	-	T4SS-DNA_transf
BYD2_k127_1015652_1	1229780.BN381_50095	5.084e-76	265.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_1015652_6	365528.KB891291_gene6505	2.172e-15	90.0	2E4TH@1|root,32ZMV@2|Bacteria,2HQNS@201174|Actinobacteria	201174|Actinobacteria	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
BYD2_k127_1015652_7	1463879.JOHP01000047_gene5505	1.769e-13	76.0	2BG1M@1|root,33HTQ@2|Bacteria,2IPY8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1015652_0	365528.KB891291_gene6508	1.585e-155	524.0	COG3451@1|root,COG3451@2|Bacteria,2I2RD@201174|Actinobacteria	201174|Actinobacteria	U	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
BYD2_k127_1015652_5	1137268.AZXF01000033_gene3403	8.452e-21	109.0	29H0P@1|root,303YC@2|Bacteria,2I815@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1034075_1	1123024.AUII01000021_gene79	1.712e-217	686.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
BYD2_k127_1034075_6	749927.AMED_3398	5.436e-94	329.0	COG2114@1|root,COG2972@1|root,COG2114@2|Bacteria,COG2972@2|Bacteria,2GJRI@201174|Actinobacteria,4DZBF@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1319c	Guanylate_cyc,HAMP
BYD2_k127_1034075_16	861299.J421_0759	3.154e-29	126.0	COG0363@1|root,COG0363@2|Bacteria	2|Bacteria	G	glucosamine-6-phosphate deaminase activity	pgl	-	3.1.1.31,3.5.99.6	ko:K01057,ko:K02564	ko00030,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00520,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R00765,R02035	RC00163,RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Glucosamine_iso
BYD2_k127_1034075_4	196162.Noca_4869	2.424e-139	452.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4DU8S@85009|Propionibacteriales	201174|Actinobacteria	G	Transaldolase/Fructose-6-phosphate aldolase	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
BYD2_k127_1034075_0	1229780.BN381_410021	1.169e-232	737.0	COG0021@1|root,COG0021@2|Bacteria,2GJ1K@201174|Actinobacteria,3UW9I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Transketolase, pyrimidine binding domain	tkt	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C,Transketolase_N
BYD2_k127_1034075_7	330214.NIDE0322	6.44e-89	312.0	COG4398@1|root,COG4398@2|Bacteria	2|Bacteria	E	FIST C domain	-	GO:0008150,GO:0040007	-	-	-	-	-	-	-	-	-	-	FIST,FIST_C
BYD2_k127_1034075_11	1313172.YM304_26220	8.4e-58	213.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
BYD2_k127_1034075_10	1229780.BN381_410015	1.28e-64	228.0	COG0045@1|root,COG0045@2|Bacteria,2I3K9@201174|Actinobacteria	201174|Actinobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5
BYD2_k127_1034075_2	1313172.YM304_26210	9.773e-211	674.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,2GKN1@201174|Actinobacteria,4CMW5@84992|Acidimicrobiia	201174|Actinobacteria	CJ	CoA binding domain	acdA1	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
BYD2_k127_1034075_9	1229780.BN381_410013	7.866e-76	286.0	COG2027@1|root,COG2027@2|Bacteria,2GJPH@201174|Actinobacteria,3UWTD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	D-Ala-D-Ala carboxypeptidase 3 (S13) family	-	-	3.4.16.4	ko:K07259	ko00550,map00550	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S13
BYD2_k127_1034075_13	1313172.YM304_26180	5.189e-50	185.0	COG2802@1|root,COG2802@2|Bacteria,2GNWA@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase S16, lon domain protein	-	-	3.4.21.53	ko:K01338,ko:K07157	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	LON_substr_bdg
BYD2_k127_1034075_17	1313172.YM304_26170	4.385e-16	91.0	28R1E@1|root,2ZDG1@2|Bacteria,2HDQB@201174|Actinobacteria,4CNE2@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
BYD2_k127_1034075_18	1122247.C731_3323	6.165e-16	85.0	COG2104@1|root,COG2104@2|Bacteria,2H07J@201174|Actinobacteria	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
BYD2_k127_1034075_5	1229780.BN381_410007	6.196e-138	449.0	COG0037@1|root,COG0037@2|Bacteria,2I9QA@201174|Actinobacteria	201174|Actinobacteria	D	PP-loop family	-	-	2.8.1.15	ko:K21947	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
BYD2_k127_1034075_8	1313172.YM304_26120	4.436e-85	303.0	COG2519@1|root,COG2519@2|Bacteria,2GJPD@201174|Actinobacteria,4CN0Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA	trmI	-	2.1.1.219,2.1.1.220	ko:K07442	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	GCD14,GCD14_N
BYD2_k127_1034075_12	1828.JOKB01000019_gene1717	2.271e-51	197.0	COG0265@1|root,COG0265@2|Bacteria,2GJ92@201174|Actinobacteria,4FU76@85025|Nocardiaceae	201174|Actinobacteria	O	Colicin V production protein	cvpA	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009268,GO:0009405,GO:0009628,GO:0010447,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	Colicin_V,Trypsin_2
BYD2_k127_1034075_15	1229780.BN381_410005	2.018e-34	134.0	COG1141@1|root,COG1141@2|Bacteria,2IKKX@201174|Actinobacteria	201174|Actinobacteria	C	ferredoxin	fdxG	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
BYD2_k127_1034075_3	1313172.YM304_26090	1.32e-197	626.0	COG1222@1|root,COG1222@2|Bacteria,2GMR1@201174|Actinobacteria,4CMRU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Proteasomal ATPase OB/ID domain	arc	-	-	ko:K13527	ko03050,map03050	M00342	-	-	ko00000,ko00001,ko00002,ko03051	-	-	-	AAA,Prot_ATP_ID_OB
BYD2_k127_1036321_0	1313172.YM304_19390	1.161e-94	322.0	COG0275@1|root,COG0275@2|Bacteria,2GJGK@201174|Actinobacteria,4CN25@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
BYD2_k127_1057252_1	1313172.YM304_08960	4.482e-103	339.0	COG0533@1|root,COG0533@2|Bacteria,2GJ98@201174|Actinobacteria,4CMUH@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
BYD2_k127_1057252_0	643473.KB235930_gene4505	3.276e-129	432.0	COG3540@1|root,COG3540@2|Bacteria,1G0C9@1117|Cyanobacteria,1HKPP@1161|Nostocales	1117|Cyanobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
BYD2_k127_1057252_3	525909.Afer_0443	2.465e-41	154.0	COG0234@1|root,COG0234@2|Bacteria,2IKTH@201174|Actinobacteria,4CN66@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
BYD2_k127_1057252_2	1463887.KL590060_gene4351	1.32e-55	195.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL2	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
BYD2_k127_1059281_2	1299327.I546_1969	1.704e-28	127.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria,236NP@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
BYD2_k127_1059281_0	419947.MRA_2836	2.752e-151	495.0	COG2801@1|root,COG2801@2|Bacteria,2I8NF@201174|Actinobacteria,236H8@1762|Mycobacteriaceae	201174|Actinobacteria	L	PFAM Integrase, catalytic	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_28,Mu-transpos_C,rve
BYD2_k127_1059281_1	1032480.MLP_18830	9.234e-35	140.0	COG3677@1|root,COG3677@2|Bacteria,2IGIB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1070558_4	1449044.JMLE01000029_gene106	4.137e-135	451.0	COG0022@1|root,COG0022@2|Bacteria,2GKFE@201174|Actinobacteria,1WAY5@1268|Micrococcaceae	201174|Actinobacteria	C	Transketolase, C-terminal domain	-	-	1.2.4.1	ko:K00162	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
BYD2_k127_1070558_3	882083.SacmaDRAFT_2626	5.459e-140	458.0	COG1071@1|root,COG1071@2|Bacteria,2IBRC@201174|Actinobacteria,4E12D@85010|Pseudonocardiales	201174|Actinobacteria	C	The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	pdhA	-	1.2.4.1	ko:K00161	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
BYD2_k127_1070558_2	1157637.KB892091_gene5383	8.501e-274	863.0	COG0365@1|root,COG0365@2|Bacteria,2GNE8@201174|Actinobacteria	201174|Actinobacteria	I	synthetase	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1070558_9	1122622.ATWJ01000013_gene208	2.201e-23	116.0	COG0599@1|root,COG0599@2|Bacteria,2IRPW@201174|Actinobacteria,4FJCM@85021|Intrasporangiaceae	201174|Actinobacteria	O	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_1070558_10	103733.JNYO01000008_gene5668	1.009e-11	78.0	COG0045@1|root,COG1042@1|root,COG1247@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,4DZ1D@85010|Pseudonocardiales	201174|Actinobacteria	C	CoA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
BYD2_k127_1070558_7	1035308.AQYY01000001_gene3293	1.383e-38	149.0	COG0071@1|root,COG0071@2|Bacteria	2|Bacteria	O	Belongs to the small heat shock protein (HSP20) family	hspX	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564	-	ko:K06335,ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
BYD2_k127_1070558_1	1304865.JAGF01000001_gene2394	0.0	1041.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
BYD2_k127_1070558_8	298655.KI912266_gene2846	2.465e-29	123.0	COG2905@1|root,COG2905@2|Bacteria,2GVP5@201174|Actinobacteria,4EWMQ@85013|Frankiales	201174|Actinobacteria	T	CBS domains	-	-	-	-	-	-	-	-	-	-	-	-	CBS,DUF1918
BYD2_k127_1070558_5	1449069.JMLO01000020_gene776	2.678e-120	392.0	COG0412@1|root,COG0412@2|Bacteria,2GK7H@201174|Actinobacteria,4FW4G@85025|Nocardiaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	DLH
BYD2_k127_1070558_6	1246995.AFR_42580	1.878e-48	178.0	COG1764@1|root,COG1764@2|Bacteria,2IFFB@201174|Actinobacteria,4DCYH@85008|Micromonosporales	201174|Actinobacteria	O	OsmC-like protein	osmC	-	-	ko:K04063	-	-	-	-	ko00000	-	-	-	OsmC
BYD2_k127_1070558_0	471852.Tcur_2667	0.0	1372.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4EGY7@85012|Streptosporangiales	201174|Actinobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
BYD2_k127_1099586_7	656024.FsymDg_3182	3.56e-48	182.0	COG3336@1|root,COG3336@2|Bacteria,2GKIR@201174|Actinobacteria,4ESB5@85013|Frankiales	201174|Actinobacteria	P	Cytochrome c oxidase caa3-type, assembly factor CtaG-related	-	-	-	ko:K02351,ko:K07245	-	-	-	-	ko00000,ko02000	9.B.62.1	-	-	Caa3_CtaG,CopD
BYD2_k127_1099586_5	1229780.BN381_20103	4.046e-63	222.0	COG0193@1|root,COG0193@2|Bacteria,2GKCV@201174|Actinobacteria,3UWQE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
BYD2_k127_1099586_8	1313172.YM304_33100	2.684e-42	163.0	COG1825@1|root,COG1825@2|Bacteria,2GJPJ@201174|Actinobacteria,4CNB1@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	rplY	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
BYD2_k127_1099586_1	1229780.BN381_20100	4.993e-132	447.0	COG0462@1|root,COG0462@2|Bacteria,2GJ9S@201174|Actinobacteria,3UW77@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)	prs	GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006015,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0040007,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046390,GO:0046391,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901576	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
BYD2_k127_1099586_3	1137271.AZUM01000002_gene2477	2.369e-92	319.0	COG1207@1|root,COG1207@2|Bacteria,2GJS1@201174|Actinobacteria,4DZZ7@85010|Pseudonocardiales	201174|Actinobacteria	M	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain	glmU	GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569	2.3.1.157,2.7.7.23	ko:K04042	ko00520,ko01100,ko01130,map00520,map01100,map01130	M00362	R00416,R05332	RC00002,RC00004,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transf_3,NTP_transferase
BYD2_k127_1099586_16	1463920.JOGB01000059_gene3970	6.585e-05	52.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria	201174|Actinobacteria	G	inositol monophosphatase	hisN	GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,3.1.3.25	ko:K01092,ko:K05602	ko00340,ko00521,ko00562,ko01100,ko01110,ko01230,ko04070,map00340,map00521,map00562,map01100,map01110,map01230,map04070	M00026,M00131	R01185,R01186,R01187,R03013	RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
BYD2_k127_1099586_15	298653.Franean1_2588	7.44e-10	70.0	2E4ST@1|root,32ZM5@2|Bacteria,2GSCH@201174|Actinobacteria,4ETEF@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
BYD2_k127_1099586_13	1306174.JODP01000021_gene278	1.4e-14	84.0	COG4961@1|root,COG4961@2|Bacteria,2GRCJ@201174|Actinobacteria	201174|Actinobacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
BYD2_k127_1099586_14	1298863.AUEP01000007_gene463	5.95e-10	68.0	2E9PN@1|root,333W1@2|Bacteria,2IT2N@201174|Actinobacteria,4DRKX@85009|Propionibacteriales	201174|Actinobacteria	S	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
BYD2_k127_1099586_6	882083.SacmaDRAFT_0059	1.695e-62	239.0	COG2064@1|root,COG2064@2|Bacteria,2HZTC@201174|Actinobacteria,4E0WX@85010|Pseudonocardiales	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
BYD2_k127_1099586_4	909613.UO65_0140	1.108e-63	228.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria,4DXBT@85010|Pseudonocardiales	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
BYD2_k127_1099586_2	1463887.KL590000_gene5709	2.867e-125	429.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system protein e	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
BYD2_k127_1099586_11	1463825.JNXC01000019_gene6512	4.095e-29	129.0	COG0455@1|root,COG0455@2|Bacteria,2HT5K@201174|Actinobacteria,4DYHS@85010|Pseudonocardiales	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1099586_17	1172188.KB911825_gene3798	0.0002094	51.0	COG3745@1|root,COG3745@2|Bacteria,2HXVP@201174|Actinobacteria,4FHYZ@85021|Intrasporangiaceae	201174|Actinobacteria	U	SAF	-	-	-	-	-	-	-	-	-	-	-	-	SAF
BYD2_k127_1099586_10	1123251.ATWM01000001_gene567	3.713e-29	132.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria,4FJBG@85021|Intrasporangiaceae	201174|Actinobacteria	NU	LysM domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,LysM
BYD2_k127_1099586_9	105422.BBPM01000013_gene3086	1.226e-38	162.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,2NFGQ@228398|Streptacidiphilus	201174|Actinobacteria	KLT	PASTA	pknL	GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
BYD2_k127_1099586_12	1123052.AUDF01000005_gene964	4.267e-16	82.0	2ETGF@1|root,33CJI@2|Bacteria,2I89U@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1099586_0	512565.AMIS_49100	6.636e-291	925.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GJBR@201174|Actinobacteria	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
BYD2_k127_110095_1	1229780.BN381_330034	9.07e-83	280.0	COG0541@1|root,COG0541@2|Bacteria,2GK4R@201174|Actinobacteria,3UWFG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
BYD2_k127_110095_5	1229780.BN381_330035	3.881e-35	137.0	COG0228@1|root,COG0228@2|Bacteria,2IKU0@201174|Actinobacteria,3UWU1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bS16 family	rpsP	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
BYD2_k127_110095_7	1229780.BN381_330036	3.41e-11	73.0	COG1837@1|root,COG1837@2|Bacteria	2|Bacteria	L	Belongs to the UPF0109 family	CP_0960	GO:0008150,GO:0040007	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
BYD2_k127_110095_3	1229780.BN381_330037	7.38e-47	184.0	COG0806@1|root,COG0806@2|Bacteria,2GK4I@201174|Actinobacteria,3UWUH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	GO:0008150,GO:0040007	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
BYD2_k127_110095_0	1229780.BN381_330038	1.799e-103	342.0	COG0336@1|root,COG0336@2|Bacteria,2GJ1G@201174|Actinobacteria,3UWGW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the RNA methyltransferase TrmD family	trmD	GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	Acetyltransf_1,tRNA_m1G_MT
BYD2_k127_110095_2	1449976.KALB_7311	1.385e-49	181.0	COG0335@1|root,COG0335@2|Bacteria,2IHRT@201174|Actinobacteria,4E3E1@85010|Pseudonocardiales	201174|Actinobacteria	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
BYD2_k127_110095_4	477641.MODMU_4410	5.314e-39	148.0	2AFXT@1|root,3161G@2|Bacteria,2IKPZ@201174|Actinobacteria,4ESWB@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF2469)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF2469
BYD2_k127_110095_6	1380356.JNIK01000016_gene3837	1.409e-21	98.0	COG0792@1|root,COG0792@2|Bacteria,2IQ3X@201174|Actinobacteria,4ETCV@85013|Frankiales	201174|Actinobacteria	L	Belongs to the UPF0102 family	yraN	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
BYD2_k127_1109801_10	351607.Acel_0379	2.987e-36	146.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_1109801_7	1089550.ATTH01000002_gene32	1.141e-55	206.0	COG0670@1|root,COG0670@2|Bacteria,4NFZ7@976|Bacteroidetes	976|Bacteroidetes	S	Belongs to the BI1 family	-	-	-	ko:K06890	-	-	-	-	ko00000	-	-	-	Bax1-I
BYD2_k127_1109801_4	931627.MycrhDRAFT_4793	6.163e-89	303.0	COG0778@1|root,COG0778@2|Bacteria,2GKG5@201174|Actinobacteria,2349B@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_1109801_0	1229780.BN381_170020	4.578e-174	556.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp123A3	GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005623,GO:0005886,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016020,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616,GO:1902652	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_1109801_8	58123.JOFJ01000003_gene2075	1.335e-50	190.0	COG1309@1|root,COG1309@2|Bacteria,2I9ZN@201174|Actinobacteria,4EP25@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1109801_3	298653.Franean1_4427	2.226e-121	401.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria,4ESD1@85013|Frankiales	201174|Actinobacteria	G	Oxidoreductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
BYD2_k127_1109801_1	1123320.KB889696_gene9123	5.362e-169	539.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
BYD2_k127_1109801_5	471852.Tcur_2585	3.873e-75	283.0	COG3173@1|root,COG3173@2|Bacteria,2I8YI@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH,EcKinase
BYD2_k127_1109801_9	134676.ACPL_3780	2.798e-50	207.0	COG0642@1|root,COG2208@1|root,COG3829@1|root,COG2205@2|Bacteria,COG2208@2|Bacteria,COG3829@2|Bacteria	2|Bacteria	T	transcription factor binding	cheR	-	2.1.1.80,2.7.11.1,2.7.13.3,3.1.1.61	ko:K04757,ko:K10125,ko:K13924	ko02020,ko02030,map02020,map02030	M00504,M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035,ko03021	-	-	-	CheR,CheR_N,GAF,GAF_2,GGDEF,HATPase_c,HATPase_c_2,HTH_18,HisKA,PAS,PAS_3,PAS_4,PAS_8,PAS_9,Response_reg,SpoIIE
BYD2_k127_1109801_11	227882.SAV_451	7.907e-11	75.0	COG1366@1|root,COG1366@2|Bacteria,2GUNY@201174|Actinobacteria	201174|Actinobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS_2
BYD2_k127_1109801_6	1121946.AUAX01000001_gene2532	1.056e-68	258.0	2AUNZ@1|root,31KBW@2|Bacteria,2GP4I@201174|Actinobacteria,4DBCM@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF2786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2786
BYD2_k127_1109801_2	1449353.JQMQ01000005_gene5848	6.871e-140	455.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,2NF1H@228398|Streptacidiphilus	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD19	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1114054_0	298654.FraEuI1c_4314	1.782e-136	436.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1114054_5	446466.Cfla_0233	6.743e-47	187.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
BYD2_k127_1114054_2	1068980.ARVW01000001_gene4347	5.868e-72	250.0	COG2258@1|root,COG2258@2|Bacteria,2GMCN@201174|Actinobacteria,4EAZU@85010|Pseudonocardiales	201174|Actinobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	3-alpha,MOSC
BYD2_k127_1114054_3	2002.JOEQ01000050_gene8399	5.073e-61	229.0	COG1309@1|root,COG1309@2|Bacteria,2GM45@201174|Actinobacteria,4EP20@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1114054_7	1206729.BAFZ01000099_gene6199	6.938e-24	116.0	COG1576@1|root,COG1576@2|Bacteria,2II1Y@201174|Actinobacteria,4G0GN@85025|Nocardiaceae	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_1114054_8	509190.Cseg_1524	7.24e-23	102.0	COG0640@1|root,COG0640@2|Bacteria,1N0HB@1224|Proteobacteria,2UDT7@28211|Alphaproteobacteria,2KHBW@204458|Caulobacterales	204458|Caulobacterales	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
BYD2_k127_1114054_9	675635.Psed_4346	2.015e-08	68.0	COG3832@1|root,COG3832@2|Bacteria,2IG6F@201174|Actinobacteria,4E4T9@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_1114054_6	1121924.ATWH01000015_gene3613	6.912e-31	141.0	COG2764@1|root,COG2764@2|Bacteria,2IIHE@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_1114054_4	405948.SACE_1731	1.324e-56	201.0	COG2329@1|root,COG2329@2|Bacteria,2GTB1@201174|Actinobacteria,4E4ZQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF3291)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3291
BYD2_k127_1114054_1	1229780.BN381_110036	4.478e-129	431.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria	201174|Actinobacteria	Q	dioxygenase	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
BYD2_k127_1116517_0	439235.Dalk_5268	4.637e-106	363.0	COG3356@1|root,COG3356@2|Bacteria,1QW1Q@1224|Proteobacteria,43BRP@68525|delta/epsilon subdivisions,2X72J@28221|Deltaproteobacteria,2MMRW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
BYD2_k127_115361_4	1262915.BN574_01471	1.057e-99	336.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,4H1Y3@909932|Negativicutes	909932|Negativicutes	J	elongation factor G	fusA_1	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
BYD2_k127_115361_19	585531.HMPREF0063_11407	1.063e-19	102.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria,4DR2D@85009|Propionibacteriales	201174|Actinobacteria	M	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
BYD2_k127_115361_10	591157.SSLG_00469	2.272e-75	258.0	COG0386@1|root,COG0386@2|Bacteria,2IFJH@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the glutathione peroxidase family	btuE	-	1.11.1.9	ko:K00432	ko00480,ko00590,ko04918,map00480,map00590,map04918	-	R00274,R07034,R07035	RC00011,RC00982	ko00000,ko00001,ko01000	-	-	-	GSHPx
BYD2_k127_115361_1	1382306.JNIM01000001_gene2629	4.129e-188	607.0	2DB7W@1|root,2Z7P1@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF4331)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4331
BYD2_k127_115361_20	1246995.AFR_20995	1.008e-08	62.0	2FF2Y@1|root,34717@2|Bacteria,2GTPB@201174|Actinobacteria,4DFKD@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_115361_11	875328.JDM601_2021	3.468e-70	250.0	COG0741@1|root,COG0741@2|Bacteria,2IBCH@201174|Actinobacteria,2359I@1762|Mycobacteriaceae	201174|Actinobacteria	M	transglycosylase	-	-	-	-	-	-	-	-	-	-	-	-	DUF1460,NLPC_P60,SLT,SLT_2
BYD2_k127_115361_5	345341.KUTG_06859	3.078e-96	317.0	COG2318@1|root,COG2318@2|Bacteria,2I1DJ@201174|Actinobacteria,4E3VZ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
BYD2_k127_115361_6	266117.Rxyl_0307	2.425e-90	309.0	COG0584@1|root,COG0584@2|Bacteria,2GM8K@201174|Actinobacteria,4CRQK@84995|Rubrobacteria	84995|Rubrobacteria	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
BYD2_k127_115361_14	1120950.KB892709_gene4139	9.851e-49	188.0	COG3801@1|root,COG3801@2|Bacteria,2IR6E@201174|Actinobacteria,4DRYH@85009|Propionibacteriales	201174|Actinobacteria	S	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_115361_13	1313172.YM304_19740	5.866e-54	204.0	2F9Q3@1|root,34209@2|Bacteria,2H616@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_115361_12	1313172.YM304_19730	1.914e-56	215.0	COG0537@1|root,COG0537@2|Bacteria,2GJT5@201174|Actinobacteria,4CN4U@84992|Acidimicrobiia	84992|Acidimicrobiia	FG	HIT domain	-	-	2.7.7.53	ko:K19710	ko00230,map00230	-	R00126,R01618	RC00002,RC02753,RC02795	ko00000,ko00001,ko01000	-	-	-	HIT
BYD2_k127_115361_0	1120950.KB892708_gene4256	7.996e-240	761.0	COG0441@1|root,COG0441@2|Bacteria,2GKTC@201174|Actinobacteria,4DN38@85009|Propionibacteriales	201174|Actinobacteria	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	thrS	GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_SAD
BYD2_k127_115361_9	1229780.BN381_50170	3.001e-79	272.0	COG0204@1|root,COG0204@2|Bacteria,2GJ6V@201174|Actinobacteria,3UWK8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
BYD2_k127_115361_3	1229780.BN381_50169	3.131e-181	586.0	COG0215@1|root,COG0215@2|Bacteria,2GJZR@201174|Actinobacteria,3UX20@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	tRNA synthetases class I (C) catalytic domain	mshC	GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576	6.1.1.16,6.3.1.13	ko:K01883,ko:K15526	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1e
BYD2_k127_115361_8	1229780.BN381_50168	1.079e-83	288.0	COG2085@1|root,COG2085@2|Bacteria,2GMZ5@201174|Actinobacteria	201174|Actinobacteria	S	PFAM NADP oxidoreductase coenzyme F420-dependent	npdG	-	1.5.1.40	ko:K06988	-	-	-	-	ko00000,ko01000	-	-	-	F420_oxidored
BYD2_k127_115361_16	1313172.YM304_31100	4.158e-35	143.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
BYD2_k127_115361_7	1229780.BN381_50167	5.835e-87	296.0	COG1119@1|root,COG1119@2|Bacteria,2GIXX@201174|Actinobacteria,3UWHV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
BYD2_k127_115361_15	1229780.BN381_290139	1.47e-44	169.0	2FJAX@1|root,34B0V@2|Bacteria,2H7B1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_115361_18	316274.Haur_2676	4.715e-29	126.0	COG1564@1|root,COG1564@2|Bacteria,2G6VK@200795|Chloroflexi,375VW@32061|Chloroflexia	32061|Chloroflexia	H	PFAM Thiamin pyrophosphokinase, catalytic region	-	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
BYD2_k127_115361_17	1068978.AMETH_6842	2.72e-30	131.0	COG1309@1|root,COG1309@2|Bacteria,2IQ7R@201174|Actinobacteria,4E5PD@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_115361_2	1123024.AUII01000016_gene1330	2.091e-187	597.0	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria,4DXM5@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_1181086_1	1150398.JIBJ01000003_gene1737	6.464e-58	205.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,1W7WN@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
BYD2_k127_1181086_0	518766.Rmar_2662	4.975e-103	355.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1FJ2X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
BYD2_k127_1181086_2	518766.Rmar_1536	3.398e-49	196.0	COG0661@1|root,COG0661@2|Bacteria,4NDUP@976|Bacteroidetes,1FJEM@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	S	ABC1 family	-	-	-	ko:K03688	-	-	-	-	ko00000	-	-	-	ABC1
BYD2_k127_1182936_2	58123.JOFJ01000016_gene3994	2.26e-35	143.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria,4EI66@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized protein family UPF0016	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
BYD2_k127_1182936_0	1313172.YM304_13810	2.675e-97	328.0	COG2141@1|root,COG2141@2|Bacteria,2GJ3B@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase, MSMEG_3544 family	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_1182936_1	1313172.YM304_27740	1.638e-51	184.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,4CMZT@84992|Acidimicrobiia	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
BYD2_k127_1192304_2	243233.MCA2161	3.502e-62	218.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1192304_0	1283283.ATXA01000001_gene504	3.006e-96	323.0	COG2267@1|root,COG2267@2|Bacteria,2GMY4@201174|Actinobacteria,4ESFU@85013|Frankiales	201174|Actinobacteria	I	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
BYD2_k127_1192304_3	331869.BAL199_01834	1.079e-36	149.0	2A0NG@1|root,32XDJ@2|Bacteria,1N3J7@1224|Proteobacteria,2UD9K@28211|Alphaproteobacteria,4BSDS@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1192304_1	570268.ANBB01000019_gene4375	3.441e-76	259.0	COG2128@1|root,COG2128@2|Bacteria,2H4IP@201174|Actinobacteria,4EPED@85012|Streptosporangiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_1192304_4	1298863.AUEP01000005_gene2551	8.431e-21	97.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4DR8S@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_1229065_3	1313172.YM304_35250	1.524e-63	251.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,2GM09@201174|Actinobacteria,4CMTF@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
BYD2_k127_1229065_1	525909.Afer_0459	1.788e-151	488.0	COG0516@1|root,COG0516@2|Bacteria,2GKVS@201174|Actinobacteria,4CNDM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	IMP dehydrogenase / GMP reductase domain	-	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
BYD2_k127_1229065_0	926550.CLDAP_30940	7.078e-175	560.0	COG0076@1|root,COG0076@2|Bacteria,2G7N6@200795|Chloroflexi	200795|Chloroflexi	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.2.27	ko:K01593,ko:K01634	ko00350,ko00360,ko00380,ko00600,ko00901,ko00950,ko00965,ko01100,ko01110,ko04071,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00600,map00901,map00950,map00965,map01100,map01110,map04071,map04726,map04728,map05030,map05031,map05034	M00037,M00042,M00100	R00685,R00699,R00736,R02080,R02464,R02701,R04909,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
BYD2_k127_1229065_2	1283299.AUKG01000001_gene3463	5.644e-81	282.0	COG1216@1|root,COG1216@2|Bacteria,2HFMY@201174|Actinobacteria,4CSCK@84995|Rubrobacteria	84995|Rubrobacteria	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_1229065_4	1394178.AWOO02000100_gene8284	2.65e-51	200.0	28KB1@1|root,2Z9Y5@2|Bacteria,2GM37@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1274873_12	164757.Mjls_2544	4.554e-17	94.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
BYD2_k127_1274873_4	1150399.AQYK01000001_gene1288	1.112e-73	266.0	COG0457@1|root,COG3903@1|root,COG0457@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4FN63@85023|Microbacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,DUF4062,NB-ARC,TPR_12
BYD2_k127_1274873_7	1298863.AUEP01000003_gene2720	2.929e-70	255.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
BYD2_k127_1274873_5	469371.Tbis_2109	1.793e-73	259.0	29QBK@1|root,30BAT@2|Bacteria,2IH7J@201174|Actinobacteria,4EC9R@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1274873_0	1229780.BN381_150138	2.752e-221	692.0	COG1960@1|root,COG1960@2|Bacteria,2HEWM@201174|Actinobacteria,3UXD0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_1274873_3	994479.GL877879_gene4428	8.859e-74	256.0	COG2353@1|root,COG2353@2|Bacteria,2IGMH@201174|Actinobacteria,4E3M3@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
BYD2_k127_1274873_2	457429.ABJI02000068_gene5126	1.47e-96	326.0	COG1396@1|root,COG1396@2|Bacteria,2HC4H@201174|Actinobacteria	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
BYD2_k127_1274873_8	33876.JNXY01000035_gene679	6.686e-50	187.0	COG3154@1|root,COG3154@2|Bacteria,2INVN@201174|Actinobacteria,4DE1S@85008|Micromonosporales	201174|Actinobacteria	I	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
BYD2_k127_1274873_6	1211815.CBYP010000034_gene2158	8.543e-71	253.0	COG5479@1|root,COG5479@2|Bacteria	2|Bacteria	M	isomerase activity	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LGFP,Phospholip_A2_3
BYD2_k127_1274873_10	882083.SacmaDRAFT_5117	5.234e-42	159.0	COG4308@1|root,COG4308@2|Bacteria,2IN4A@201174|Actinobacteria,4E4Z1@85010|Pseudonocardiales	201174|Actinobacteria	Q	Limonene-1,2-epoxide hydrolase catalytic domain	ephG	GO:0003674,GO:0003824,GO:0004301,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016801,GO:0016803,GO:0018904,GO:0033963,GO:0044237,GO:0044281,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0097176,GO:1901360	3.3.2.8	ko:K10533	ko00903,map00903	-	R05784,R09387	RC01473,RC02519	ko00000,ko00001,ko01000	-	-	-	LEH
BYD2_k127_1274873_9	298655.KI912267_gene6881	1.176e-48	198.0	2EACJ@1|root,334GH@2|Bacteria,2IG8C@201174|Actinobacteria	201174|Actinobacteria	S	Limonene-12-epoxide hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	LEH,SnoaL_2
BYD2_k127_1274873_1	219305.MCAG_00520	4.801e-210	668.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
BYD2_k127_1322757_0	1122609.AUGT01000029_gene2619	4.389e-67	247.0	COG2856@1|root,COG2856@2|Bacteria,2GPBB@201174|Actinobacteria,4DTVM@85009|Propionibacteriales	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1322757_2	1229780.BN381_110083	2.554e-53	199.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH
BYD2_k127_1322757_5	1394178.AWOO02000018_gene6530	4.592e-39	155.0	COG2346@1|root,COG2346@2|Bacteria,2IKPF@201174|Actinobacteria,4EJN6@85012|Streptosporangiales	201174|Actinobacteria	S	Bacterial-like globin	glbO	GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
BYD2_k127_1322757_1	1313172.YM304_17780	2.66e-60	223.0	COG1225@1|root,COG1225@2|Bacteria,2IHZ6@201174|Actinobacteria,4CN8N@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
BYD2_k127_1322757_6	929712.KI912613_gene1652	2.832e-28	127.0	COG1595@1|root,COG1595@2|Bacteria,2II47@201174|Actinobacteria,4CSB0@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_1322757_4	266940.Krad_2866	1.178e-52	200.0	COG0350@1|root,COG0350@2|Bacteria,2GKA9@201174|Actinobacteria	201174|Actinobacteria	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	ogt	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
BYD2_k127_1322757_3	471852.Tcur_2861	4.447e-53	193.0	COG3780@1|root,COG3780@2|Bacteria,2HX4P@201174|Actinobacteria,4EQYW@85012|Streptosporangiales	201174|Actinobacteria	L	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1350378_6	1229780.BN381_310016	7.556e-31	136.0	COG0028@1|root,COG0028@2|Bacteria,2H8JC@201174|Actinobacteria	201174|Actinobacteria	EH	Thiamine pyrophosphate enzyme, central domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_M
BYD2_k127_1350378_2	1123320.KB889675_gene3901	1.605e-83	301.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
BYD2_k127_1350378_3	298654.FraEuI1c_5748	2.452e-71	253.0	COG2141@1|root,COG2141@2|Bacteria,2GMUP@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_1350378_4	882083.SacmaDRAFT_3053	2.25e-46	182.0	COG1168@1|root,COG1168@2|Bacteria	2|Bacteria	E	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
BYD2_k127_1350378_5	58344.JOEL01000038_gene4039	1.557e-35	145.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
BYD2_k127_1350378_7	43354.JOIJ01000002_gene4581	2.997e-30	133.0	2DMQN@1|root,32T1U@2|Bacteria,2GS5T@201174|Actinobacteria,4E6JM@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Branched-chain amino acid transport protein (AzlD)	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
BYD2_k127_1350378_1	479435.Kfla_1552	1.262e-89	300.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4DQH9@85009|Propionibacteriales	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
BYD2_k127_1350378_0	1449069.JMLO01000011_gene2457	8.328e-97	319.0	COG1396@1|root,COG1396@2|Bacteria,2GXAS@201174|Actinobacteria,4FX1F@85025|Nocardiaceae	201174|Actinobacteria	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
BYD2_k127_1350378_8	298654.FraEuI1c_4763	3.386e-10	60.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EU6F@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.41	ko:K00666,ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1366404_0	1121877.JQKF01000003_gene1540	1.434e-59	214.0	COG0018@1|root,COG0018@2|Bacteria,2GKQ3@201174|Actinobacteria,4CNAI@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Arginyl tRNA synthetase N terminal dom	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
BYD2_k127_1366404_1	365528.KB891285_gene5013	1.006e-30	132.0	COG0582@1|root,COG0582@2|Bacteria,2GJ2M@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
BYD2_k127_1379782_6	240016.ABIZ01000001_gene684	8.334e-35	149.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	3.5.1.28	ko:K03806	-	-	-	-	ko00000,ko01000,ko01011	-	-	-	Acetyltransf_1,Acetyltransf_7,Amidase_2,rRNA_methylase
BYD2_k127_1379782_2	1229780.BN381_110056	1.886e-95	317.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,3UXDW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_1379782_5	1229780.BN381_150073	4.281e-57	216.0	COG4585@1|root,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,3UWXU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Histidine kinase-like ATPases	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
BYD2_k127_1379782_1	298653.Franean1_1216	5.65e-104	357.0	COG0477@1|root,COG0477@2|Bacteria,2GKY2@201174|Actinobacteria,4EUMC@85013|Frankiales	201174|Actinobacteria	EGP	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_1379782_4	298655.KI912266_gene1438	3.418e-64	229.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria,4ESSZ@85013|Frankiales	201174|Actinobacteria	M	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
BYD2_k127_1379782_3	1313172.YM304_03920	1.118e-92	315.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,4CMZ7@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
BYD2_k127_1379782_0	1151061.CAJY01000005_gene2757	1.291e-261	814.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria	201174|Actinobacteria	O	associated with various cellular activities	clpC	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N,UVR
BYD2_k127_1383130_8	1504822.CCNO01000015_gene570	4.572e-42	166.0	COG4166@1|root,COG4166@2|Bacteria	2|Bacteria	E	transmembrane transport	-	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5,TAT_signal
BYD2_k127_1383130_6	742742.HMPREF9452_00045	1.156e-71	254.0	COG0601@1|root,COG0601@2|Bacteria,2GJ2C@201174|Actinobacteria,4CUGS@84998|Coriobacteriia	84998|Coriobacteriia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
BYD2_k127_1383130_5	883112.HMPREF9707_00808	1.827e-78	291.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,4HBB9@91061|Bacilli	91061|Bacilli	EP	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
BYD2_k127_1383130_3	566461.SSFG_02568	1.245e-111	374.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	bldKD	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
BYD2_k127_1383130_1	1179773.BN6_08500	2.391e-133	437.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4DXRP@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
BYD2_k127_1383130_9	1121877.JQKF01000028_gene2137	3.523e-18	87.0	COG1314@1|root,COG1314@2|Bacteria,2HGDT@201174|Actinobacteria,4CNCC@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Preprotein translocase SecG subunit	-	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
BYD2_k127_1383130_7	28042.GU90_16815	1.169e-69	241.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4E49V@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
BYD2_k127_1383130_0	525909.Afer_1569	0.0	1133.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4CMWW@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
BYD2_k127_1383130_4	1313172.YM304_33320	2.962e-96	353.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4CMQN@84992|Acidimicrobiia	84992|Acidimicrobiia	C	CO dehydrogenase flavoprotein C-terminal domain	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
BYD2_k127_1383130_2	1313172.YM304_33360	1.684e-119	394.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4CMRT@84992|Acidimicrobiia	84992|Acidimicrobiia	O	AAA domain (dynein-related subfamily)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
BYD2_k127_1383130_10	1313172.YM304_33370	3.08e-06	57.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CNNX@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
BYD2_k127_1392709_0	1078020.KEK_14233	3.345e-80	280.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,233UJ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	cyp142A3	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
BYD2_k127_1392709_1	935839.JAGJ01000004_gene2071	7.088e-06	59.0	COG1309@1|root,COG1309@2|Bacteria,2I8DJ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1400846_0	390989.JOEG01000012_gene3403	5.08e-226	713.0	COG0433@1|root,COG0433@2|Bacteria,2I0H5@201174|Actinobacteria,4D9TP@85008|Micromonosporales	201174|Actinobacteria	S	COG0433 Predicted ATPase	-	-	-	ko:K06915	-	-	-	-	ko00000	-	-	-	-
BYD2_k127_1400846_1	390989.JOEG01000012_gene3413	1.867e-84	288.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4D95R@85008|Micromonosporales	201174|Actinobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
BYD2_k127_1410990_12	1157635.KB892032_gene6112	3.244e-07	56.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,Sugar_tr
BYD2_k127_1410990_9	670307.HYPDE_40493	7.846e-24	113.0	COG0530@1|root,COG0530@2|Bacteria,1PMPV@1224|Proteobacteria,2V8K9@28211|Alphaproteobacteria,3N8Y2@45401|Hyphomicrobiaceae	28211|Alphaproteobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
BYD2_k127_1410990_6	1429046.RR21198_2274	1.316e-67	236.0	COG1576@1|root,COG1576@2|Bacteria,2I35D@201174|Actinobacteria,4GA0E@85025|Nocardiaceae	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_1410990_0	1078020.KEK_02035	5.751e-238	774.0	COG0477@1|root,COG0815@1|root,COG0815@2|Bacteria,COG2814@2|Bacteria,2GP5I@201174|Actinobacteria,23418@1762|Mycobacteriaceae	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
BYD2_k127_1410990_2	1313172.YM304_22510	6.856e-107	361.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
BYD2_k127_1410990_1	471852.Tcur_4171	1.459e-115	382.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4EGQA@85012|Streptosporangiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_1410990_5	512565.AMIS_10150	1.011e-81	305.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria,4DCA7@85008|Micromonosporales	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_1410990_3	1157640.AQWO01000010_gene2827	7.258e-104	344.0	COG0596@1|root,COG0596@2|Bacteria,2GNFU@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6
BYD2_k127_1410990_4	1464048.JNZS01000010_gene5159	7.66e-86	318.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
BYD2_k127_1410990_8	1313172.YM304_23250	1.316e-50	197.0	COG0730@1|root,COG0730@2|Bacteria,2HGFT@201174|Actinobacteria,4CNDC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
BYD2_k127_1410990_7	1380356.JNIK01000019_gene261	3.091e-54	198.0	COG0346@1|root,COG0346@2|Bacteria,2IJX2@201174|Actinobacteria,4EVM1@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_1410990_11	298654.FraEuI1c_3065	9.054e-08	53.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
BYD2_k127_1412373_3	1123024.AUII01000048_gene805	2.538e-143	455.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria,4DZ3D@85010|Pseudonocardiales	201174|Actinobacteria	L	Excinuclease ATPase subunit	uvrA2	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
BYD2_k127_1412373_6	561175.KB894100_gene4785	1.328e-96	325.0	COG0346@1|root,COG0346@2|Bacteria,2IS4J@201174|Actinobacteria,4EPSM@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_1412373_10	1380390.JIAT01000009_gene664	2.615e-57	203.0	COG3832@1|root,COG3832@2|Bacteria,2II8T@201174|Actinobacteria,4CQRH@84995|Rubrobacteria	84995|Rubrobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_1412373_2	690585.JNNU01000004_gene4053	9e-170	541.0	COG0620@1|root,COG0620@2|Bacteria,1MUI9@1224|Proteobacteria,2TTWK@28211|Alphaproteobacteria,4BDWB@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Cobalamin-independent synthase, Catalytic domain	metE	-	2.1.1.14,4.4.1.23	ko:K00549,ko:K22363	ko00270,ko00450,ko00625,ko01100,ko01110,ko01230,map00270,map00450,map00625,map01100,map01110,map01230	M00017	R04405,R09365,R11897,R11899	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
BYD2_k127_1412373_17	994479.GL877878_gene1314	9.38e-29	123.0	COG1309@1|root,COG1309@2|Bacteria,2HG87@201174|Actinobacteria,4E69G@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	tcmR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1412373_1	479431.Namu_0497	2.13e-183	603.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU1V@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_1412373_16	1229780.BN381_350095	2.557e-31	141.0	COG0526@1|root,COG0526@2|Bacteria,2H8ZP@201174|Actinobacteria	201174|Actinobacteria	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1412373_15	867903.ThesuDRAFT_00844	7.607e-33	135.0	COG1495@1|root,COG1495@2|Bacteria,1V79S@1239|Firmicutes,253UQ@186801|Clostridia	186801|Clostridia	C	PFAM Disulfide bond formation protein DsbB	-	-	-	ko:K03611	-	-	-	-	ko00000,ko03110	5.A.2.1	-	-	DsbB
BYD2_k127_1412373_4	390989.JOEG01000006_gene747	1.025e-136	449.0	COG1626@1|root,COG1626@2|Bacteria,2I1MU@201174|Actinobacteria,4DCE4@85008|Micromonosporales	201174|Actinobacteria	G	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_63,Trehalase
BYD2_k127_1412373_14	105420.BBPO01000045_gene1080	9.23e-34	147.0	COG3576@1|root,COG3576@2|Bacteria,2IG3P@201174|Actinobacteria,2NMBD@228398|Streptacidiphilus	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_1412373_0	1121877.JQKF01000001_gene1341	0.0	1313.0	COG0646@1|root,COG1410@1|root,COG0646@2|Bacteria,COG1410@2|Bacteria,2GM5Q@201174|Actinobacteria,4CN9K@84992|Acidimicrobiia	84992|Acidimicrobiia	H	B12 binding domain	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Met_synt_B12,Pterin_bind,S-methyl_trans
BYD2_k127_1412373_11	2002.JOEQ01000003_gene2375	2.766e-56	208.0	COG1309@1|root,COG1309@2|Bacteria,2GJ7G@201174|Actinobacteria,4EJK5@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1412373_5	711393.AYRX01000024_gene1404	1.709e-111	367.0	COG1801@1|root,COG1801@2|Bacteria,2GMSP@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
BYD2_k127_1412373_19	797114.C475_09434	8.934e-19	97.0	arCOG11971@1|root,arCOG11971@2157|Archaea,2XWIZ@28890|Euryarchaeota,23VA2@183963|Halobacteria	183963|Halobacteria	S	YndJ-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YndJ
BYD2_k127_1412373_8	321332.CYB_1677	5.92e-89	303.0	COG0111@1|root,COG0111@2|Bacteria,1G417@1117|Cyanobacteria,1H2J2@1129|Synechococcus	1117|Cyanobacteria	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	2-Hacid_dh,2-Hacid_dh_C
BYD2_k127_1412373_9	1068978.AMETH_5639	8.638e-59	210.0	COG1051@1|root,COG1051@2|Bacteria,2II3B@201174|Actinobacteria,4EE99@85010|Pseudonocardiales	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_1412373_12	1229780.BN381_80027	3.893e-55	209.0	COG2096@1|root,COG2096@2|Bacteria,2GMHN@201174|Actinobacteria,3UWVY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Cobalamin adenosyltransferase	yvqK	-	2.5.1.17	ko:K00798	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	Cob_adeno_trans
BYD2_k127_1412373_7	471852.Tcur_3385	9.476e-95	326.0	COG1028@1|root,COG1028@2|Bacteria,2GMEH@201174|Actinobacteria,4EMUX@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
BYD2_k127_1412373_18	471852.Tcur_3353	4.776e-24	106.0	2E7QZ@1|root,3326A@2|Bacteria,2GR1A@201174|Actinobacteria,4EKGI@85012|Streptosporangiales	201174|Actinobacteria	S	Stress responsive A/B Barrel Domain	-	-	-	-	-	-	-	-	-	-	-	-	Dabb
BYD2_k127_1412373_13	1242864.D187_003185	1.328e-39	160.0	COG2815@1|root,COG2815@2|Bacteria,1RIP7@1224|Proteobacteria,42XQG@68525|delta/epsilon subdivisions,2WT9P@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	TIR domain	-	-	-	-	-	-	-	-	-	-	-	-	TIR_2
BYD2_k127_1417859_23	1394178.AWOO02000038_gene9084	3.238e-22	101.0	COG0789@1|root,COG0789@2|Bacteria,2IKRG@201174|Actinobacteria,4EP1N@85012|Streptosporangiales	201174|Actinobacteria	K	MerR, DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
BYD2_k127_1417859_4	196162.Noca_4966	9.185e-189	618.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994,ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_1417859_7	671143.DAMO_0766	1.518e-168	550.0	COG0493@1|root,COG1143@1|root,COG0493@2|Bacteria,COG1143@2|Bacteria,2NNUW@2323|unclassified Bacteria	2|Bacteria	C	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster	pcmB	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9	ko:K03388,ko:K12527	ko00450,ko00680,ko01100,ko01120,ko01200,map00450,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R07229,R11928,R11931,R11943,R11944	RC00011,RC02420	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,FlpD,Pyr_redox_2,Pyr_redox_3
BYD2_k127_1417859_16	234267.Acid_3505	6.519e-79	271.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	petB	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
BYD2_k127_1417859_19	1382306.JNIM01000001_gene1048	2.158e-44	169.0	COG1290@1|root,COG1290@2|Bacteria	2|Bacteria	C	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis	pcmD	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C,Cytochrome_B
BYD2_k127_1417859_22	1229780.BN381_450009	4.76e-25	111.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
BYD2_k127_1417859_28	715451.ambt_08795	9.287e-10	70.0	COG0607@1|root,COG2010@1|root,COG0607@2|Bacteria,COG2010@2|Bacteria,1R6Z0@1224|Proteobacteria,1RXZ9@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	Cytochrome c	-	-	-	ko:K00406	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00156	-	-	ko00000,ko00001,ko00002	3.D.4.3	-	-	Cytochrome_CBB3,Rhodanese
BYD2_k127_1417859_27	1089545.KB913037_gene1517	8.308e-17	82.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
BYD2_k127_1417859_5	1380390.JIAT01000010_gene3933	2.384e-187	600.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_1417859_24	43759.JNWK01000057_gene2607	2.756e-21	104.0	COG1474@1|root,COG1474@2|Bacteria,2I4DX@201174|Actinobacteria	201174|Actinobacteria	LO	Belongs to the peptidase S16 family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1417859_18	1120949.KB903301_gene6396	4.622e-58	208.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_1417859_3	348824.LPU83_3304	3.684e-191	606.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,4B7GV@82115|Rhizobiaceae	28211|Alphaproteobacteria	Q	epoxide hydrolase	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
BYD2_k127_1417859_13	543632.JOJL01000023_gene1731	2.929e-96	321.0	COG1073@1|root,COG1073@2|Bacteria,2I2SC@201174|Actinobacteria,4D9P3@85008|Micromonosporales	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_1417859_21	2002.JOEQ01000022_gene6859	3.355e-32	136.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,4EFJJ@85012|Streptosporangiales	201174|Actinobacteria	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
BYD2_k127_1417859_1	1380390.JIAT01000010_gene3898	0.0	1111.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4CR4U@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_1417859_26	1123320.KB889697_gene9027	1.775e-18	92.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
BYD2_k127_1417859_8	1304865.JAGF01000001_gene2033	3.632e-142	460.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria	201174|Actinobacteria	G	polyphosphate kinase	ppk2	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006183,GO:0006464,GO:0006468,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030808,GO:0031323,GO:0031326,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0036211,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046777,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051704,GO:0055086,GO:0062012,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0080090,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
BYD2_k127_1417859_10	1283283.ATXA01000021_gene2882	7.207e-111	368.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ES16@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_1417859_15	1380346.JNIH01000027_gene5812	7.852e-88	298.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
BYD2_k127_1417859_0	1386089.N865_16515	0.0	1137.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4FG7V@85021|Intrasporangiaceae	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
BYD2_k127_1417859_11	1122622.ATWJ01000011_gene2138	6.266e-107	361.0	COG2239@1|root,COG2239@2|Bacteria,2I9TV@201174|Actinobacteria	201174|Actinobacteria	P	Divalent cation transporter	-	-	-	ko:K06213	-	-	-	-	ko00000,ko02000	1.A.26.1	-	-	CBS,MgtE
BYD2_k127_1417859_14	1313172.YM304_26770	5.182e-95	321.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CMST@84992|Acidimicrobiia	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Helicase_C,ResIII,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_1417859_12	1173263.Syn7502_03166	5.922e-105	348.0	COG0596@1|root,COG0596@2|Bacteria,1G0CB@1117|Cyanobacteria,1H3YW@1129|Synechococcus	1117|Cyanobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_1417859_25	222534.KB893778_gene5093	4.014e-19	92.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_1417859_2	404589.Anae109_2815	2.574e-224	713.0	COG1018@1|root,COG2258@1|root,COG1018@2|Bacteria,COG2258@2|Bacteria,1MU6E@1224|Proteobacteria,43AGX@68525|delta/epsilon subdivisions,2X5WW@28221|Deltaproteobacteria,2YVNA@29|Myxococcales	28221|Deltaproteobacteria	C	2Fe-2S iron-sulfur cluster binding domain	-	-	1.14.14.47	ko:K00491,ko:K21324	ko00220,ko00330,ko01100,ko01110,map00220,map00330,map01100,map01110	-	R11711,R11712,R11713	RC00177,RC00330,RC01044	ko00000,ko00001,ko01000	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
BYD2_k127_1417859_6	656024.FsymDg_0028	8.211e-179	571.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4ESCB@85013|Frankiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
BYD2_k127_1417859_17	1380390.JIAT01000009_gene611	5.081e-63	226.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4CSI7@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
BYD2_k127_1417859_9	469383.Cwoe_0403	2.75e-116	413.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
BYD2_k127_1417859_20	296591.Bpro_1404	2.843e-43	160.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2VQB7@28216|Betaproteobacteria,4AFVE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,Sacchrp_dh_NADP
BYD2_k127_1427058_0	335543.Sfum_1219	1.846e-146	473.0	COG0436@1|root,COG0436@2|Bacteria,1MWS8@1224|Proteobacteria,42MEF@68525|delta/epsilon subdivisions,2WJ4D@28221|Deltaproteobacteria,2MQW6@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	PFAM Aminotransferase class I and II	yfdZ	-	2.6.1.83	ko:K10206,ko:K14261	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
BYD2_k127_1427058_4	570268.ANBB01000035_gene2355	1.079e-61	216.0	COG0221@1|root,COG0221@2|Bacteria,2GM7F@201174|Actinobacteria,4EHYC@85012|Streptosporangiales	201174|Actinobacteria	C	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions	ppa	GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0071944	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3628	Pyrophosphatase
BYD2_k127_1427058_3	1313172.YM304_19170	8.988e-78	286.0	COG1940@1|root,COG1940@2|Bacteria,2GJA0@201174|Actinobacteria,4CNH1@84992|Acidimicrobiia	201174|Actinobacteria	G	ROK family	ppgK	-	2.7.1.2,2.7.1.63	ko:K00845,ko:K00886	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786,R02187,R02189	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
BYD2_k127_1427058_6	926569.ANT_25860	7.592e-29	133.0	COG1503@1|root,COG1503@2|Bacteria,2G745@200795|Chloroflexi	200795|Chloroflexi	J	translation release factor activity	-	-	-	ko:K03265	ko03015,map03015	-	-	-	ko00000,ko00001,ko03012,ko03019	-	-	-	eRF1_2,eRF1_3
BYD2_k127_1427058_1	397278.JOJN01000004_gene1185	4.838e-108	370.0	COG0003@1|root,COG0003@2|Bacteria,2GISZ@201174|Actinobacteria,4DPCJ@85009|Propionibacteriales	201174|Actinobacteria	P	Anion-transporting ATPase	arsA	-	3.6.3.16	ko:K01551	-	-	-	-	ko00000,ko01000,ko02000	3.A.19.1,3.A.21.1,3.A.4.1	-	-	ArsA_ATPase
BYD2_k127_1427058_5	1313172.YM304_19160	2.052e-36	143.0	COG2867@1|root,COG2867@2|Bacteria,2IFH4@201174|Actinobacteria,4CN9D@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc
BYD2_k127_1427058_2	345341.KUTG_01076	1.224e-95	329.0	COG0500@1|root,COG2226@2|Bacteria,2GJSF@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_1427058_7	1313172.YM304_19150	1.127e-11	72.0	28Z2K@1|root,2ZKV3@2|Bacteria,2HA4X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1434775_1	1227487.C474_04510	8.267e-78	272.0	COG2146@1|root,arCOG02852@2157|Archaea,2XUZH@28890|Euryarchaeota,23SZ3@183963|Halobacteria	183963|Halobacteria	P	COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
BYD2_k127_1434775_0	1229780.BN381_80295	1.921e-164	527.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
BYD2_k127_1434775_3	1122611.KB903940_gene1815	7.158e-22	104.0	COG1309@1|root,COG1309@2|Bacteria,2GUIR@201174|Actinobacteria,4EM84@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1434775_2	487521.OCU_44080	5.655e-68	235.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,2374Z@1762|Mycobacteriaceae	201174|Actinobacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_1463819_3	1449347.JQLN01000006_gene2726	3.568e-13	70.0	COG3832@1|root,COG3832@2|Bacteria,2IMFE@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_1463819_1	1283299.AUKG01000002_gene5228	7.09e-46	181.0	COG3576@1|root,COG3576@2|Bacteria,2H5HQ@201174|Actinobacteria,4CRVN@84995|Rubrobacteria	84995|Rubrobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_1465080_2	926564.KI911760_gene4791	1.504e-102	337.0	COG1209@1|root,COG1209@2|Bacteria,2GP20@201174|Actinobacteria,4F352@85017|Promicromonosporaceae	201174|Actinobacteria	M	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
BYD2_k127_1465080_0	570268.ANBB01000002_gene218	3.893e-151	485.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4EGFJ@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_1465080_1	1229780.BN381_10277	9.508e-138	444.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,3UXGG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	NMO
BYD2_k127_1495839_13	1229780.BN381_90006	1.051e-46	177.0	COG1028@1|root,COG1028@2|Bacteria,2GM3I@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_1495839_10	1229780.BN381_350102	1.931e-73	256.0	COG1028@1|root,COG1028@2|Bacteria,2GMAG@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase	-	GO:0003674,GO:0003824,GO:0004799,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008168,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016740,GO:0016741,GO:0019889,GO:0032259,GO:0033554,GO:0034599,GO:0042083,GO:0042221,GO:0042558,GO:0044237,GO:0046483,GO:0047040,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071704,GO:1901360,GO:1901564	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_1495839_11	1160137.KB907307_gene3904	2.808e-55	205.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4FU5R@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
BYD2_k127_1495839_3	1313172.YM304_03270	2.273e-120	406.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,4CNI4@84992|Acidimicrobiia	84992|Acidimicrobiia	JKL	DEAD-like helicases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
BYD2_k127_1495839_12	365528.KB891137_gene399	7.014e-54	200.0	COG0496@1|root,COG0496@2|Bacteria,2IRBR@201174|Actinobacteria,4EVR8@85013|Frankiales	201174|Actinobacteria	S	Survival protein SurE	-	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
BYD2_k127_1495839_14	33898.JRHJ01000087_gene2355	5.996e-36	152.0	COG3568@1|root,COG3568@2|Bacteria,2GNF9@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_1495839_1	471852.Tcur_2574	3.799e-125	416.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
BYD2_k127_1495839_16	1996.JOFO01000004_gene3534	3.314e-22	104.0	COG0589@1|root,COG0589@2|Bacteria,2IQPQ@201174|Actinobacteria,4EPZ3@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
BYD2_k127_1495839_2	471852.Tcur_1250	5.793e-122	399.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4EQRC@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_1495839_5	1380356.JNIK01000013_gene4169	4.354e-103	359.0	COG4907@1|root,COG4907@2|Bacteria,2GNW7@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
BYD2_k127_1495839_0	67275.JOAP01000001_gene2775	8.473e-238	768.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_1495839_4	471852.Tcur_2301	3.649e-110	375.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EH5C@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_1495839_17	390989.JOEG01000021_gene2647	5.312e-15	86.0	COG3595@1|root,COG3595@2|Bacteria,2HUCP@201174|Actinobacteria,4DG6I@85008|Micromonosporales	201174|Actinobacteria	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
BYD2_k127_1495839_9	1449353.JQMQ01000005_gene4350	2.278e-76	285.0	COG2197@1|root,COG2197@2|Bacteria,2HNBW@201174|Actinobacteria,2NI1S@228398|Streptacidiphilus	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_1495839_7	1120936.KB907211_gene89	1.101e-84	297.0	COG4585@1|root,COG4585@2|Bacteria,2GIXR@201174|Actinobacteria,4EHEE@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3,Sensor
BYD2_k127_1495839_15	1229780.BN381_400003	8.065e-33	136.0	COG5517@1|root,COG5517@2|Bacteria,2II1F@201174|Actinobacteria	201174|Actinobacteria	Q	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
BYD2_k127_1495839_8	1463920.JOGB01000016_gene5464	6.249e-78	277.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
BYD2_k127_1495839_6	66377.JOBH01000002_gene674	7.331e-95	336.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_1564947_2	298654.FraEuI1c_5256	9.496e-87	295.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1564947_4	1220583.GOACH_03_01920	0.0002298	44.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4GBY8@85026|Gordoniaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	aldA	GO:0000166,GO:0003674,GO:0003824,GO:0004029,GO:0004030,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0006066,GO:0006067,GO:0006069,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0022900,GO:0031974,GO:0034308,GO:0036094,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901615	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_1564947_3	471852.Tcur_2580	1.78e-05	56.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_1564947_1	471852.Tcur_2579	2.972e-104	344.0	COG1028@1|root,COG1028@2|Bacteria,2HP88@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
BYD2_k127_1564947_0	298654.FraEuI1c_4763	2.497e-206	655.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EU6F@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.41	ko:K00666,ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1585953_4	298653.Franean1_2973	1.451e-97	337.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,4ES18@85013|Frankiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain protein	paaE	-	-	ko:K02613	ko00360,ko01120,map00360,map01120	-	R09838	RC02690	ko00000,ko00001	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
BYD2_k127_1585953_0	1306990.BARG01000038_gene4481	1.718e-201	642.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1585953_2	1160137.KB907307_gene1826	3.419e-116	379.0	COG2175@1|root,COG2175@2|Bacteria,2GNUC@201174|Actinobacteria,4FYX5@85025|Nocardiaceae	201174|Actinobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	tfdA	-	1.14.11.17	ko:K03119	ko00430,ko00920,map00430,map00920	-	R05320	RC01331	ko00000,ko00001,ko01000	-	-	-	TauD
BYD2_k127_1585953_3	1172185.KB911512_gene5048	3.915e-103	355.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria,4FZ6B@85025|Nocardiaceae	201174|Actinobacteria	IQ	KR domain	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
BYD2_k127_1585953_5	1206730.BAGA01000182_gene2956	1.577e-40	171.0	COG1309@1|root,COG1309@2|Bacteria,2GNJZ@201174|Actinobacteria,4FUPU@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1585953_1	1229780.BN381_250032	1.792e-189	608.0	28JDP@1|root,2Z97Z@2|Bacteria,2I9EC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1589630_22	882082.SaccyDRAFT_2558	1.977e-50	184.0	COG1846@1|root,COG1846@2|Bacteria,2GP6A@201174|Actinobacteria,4E4U7@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BYD2_k127_1589630_17	1229780.BN381_60058	1.722e-72	261.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,3UWSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	YceI-like domain	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
BYD2_k127_1589630_5	1229780.BN381_450063	7.074e-190	605.0	COG0281@1|root,COG0281@2|Bacteria,2GJAJ@201174|Actinobacteria,3UX3I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Malic enzyme, NAD binding domain	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	ACT,ACT_4,Malic_M,malic
BYD2_k127_1589630_12	44251.PDUR_05950	3.092e-115	385.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,4HAB2@91061|Bacilli,26Q8R@186822|Paenibacillaceae	91061|Bacilli	E	Belongs to the Glu Leu Phe Val dehydrogenases family	ldh	-	1.4.1.9	ko:K00263	ko00280,ko00290,ko01100,ko01110,ko01130,map00280,map00290,map01100,map01110,map01130	-	R01088,R01434,R02196	RC00006,RC00036	ko00000,ko00001,ko01000	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
BYD2_k127_1589630_21	1313172.YM304_38880	5.202e-51	200.0	COG0461@1|root,COG0461@2|Bacteria,2HG8J@201174|Actinobacteria,4CN64@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
BYD2_k127_1589630_11	1229780.BN381_130022	3.13e-117	388.0	COG0150@1|root,COG0150@2|Bacteria,2GJNY@201174|Actinobacteria,3UWBB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	AIR synthase related protein, C-terminal domain	purM	GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016882,GO:0044424,GO:0044444,GO:0044464	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
BYD2_k127_1589630_6	1121946.AUAX01000006_gene3564	6.036e-144	473.0	COG0034@1|root,COG0034@2|Bacteria,2GK6I@201174|Actinobacteria,4DB2D@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	GO:0008150,GO:0040007	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
BYD2_k127_1589630_34	525909.Afer_1833	3.22e-18	94.0	COG2246@1|root,COG2246@2|Bacteria,2HGRJ@201174|Actinobacteria,4CNUB@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GtrA-like protein	-	-	-	-	-	-	-	-	-	-	-	-	GtrA
BYD2_k127_1589630_2	1229780.BN381_130019	7.528e-294	926.0	COG0046@1|root,COG0046@2|Bacteria,2GKG6@201174|Actinobacteria,3UWF7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purL	GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
BYD2_k127_1589630_29	1313172.YM304_38910	4.959e-33	132.0	2A58G@1|root,30TXM@2|Bacteria,2HG9Z@201174|Actinobacteria,4CN8R@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1589630_15	1229780.BN381_130016	4.475e-96	323.0	COG0047@1|root,COG0047@2|Bacteria,2GMJY@201174|Actinobacteria,3UWG1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase_5
BYD2_k127_1589630_31	1229780.BN381_130015	2.375e-26	111.0	COG1828@1|root,COG1828@2|Bacteria	2|Bacteria	F	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL	purS	-	6.3.2.6,6.3.5.3	ko:K01923,ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463,R04591	RC00010,RC00064,RC00162,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU06460	PurS
BYD2_k127_1589630_13	1229780.BN381_130013	8.523e-101	352.0	COG0152@1|root,COG0152@2|Bacteria,2GK3H@201174|Actinobacteria,3UWES@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	SAICAR synthetase	purC	GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	6.3.2.6,6.3.4.13	ko:K01923,ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04591	RC00064,RC00090,RC00162,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
BYD2_k127_1589630_4	909613.UO65_5776	1.699e-218	688.0	COG0015@1|root,COG0015@2|Bacteria,2GKBR@201174|Actinobacteria,4E0FG@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
BYD2_k127_1589630_23	1384066.JAGT01000001_gene1594	7.577e-48	179.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3WITM@541000|Ruminococcaceae	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
BYD2_k127_1589630_9	1229780.BN381_130009	2.816e-134	442.0	COG0151@1|root,COG0151@2|Bacteria,2I2F5@201174|Actinobacteria,3UW9D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphoribosylglycinamide synthetase, C domain	purD	GO:0008150,GO:0040007	6.3.3.1,6.3.4.13	ko:K01945,ko:K11788	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144,R04208	RC00090,RC00166,RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
BYD2_k127_1589630_3	1229780.BN381_130003	2.467e-219	687.0	COG0104@1|root,COG0104@2|Bacteria,2GMP4@201174|Actinobacteria,3UWF4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
BYD2_k127_1589630_25	240292.Ava_1042	5.778e-38	155.0	COG1216@1|root,COG1216@2|Bacteria,1G2TX@1117|Cyanobacteria	1117|Cyanobacteria	Q	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1589630_27	756067.MicvaDRAFT_2450	4.085e-37	153.0	COG0438@1|root,COG0457@1|root,COG0463@1|root,COG2518@1|root,COG0438@2|Bacteria,COG0457@2|Bacteria,COG0463@2|Bacteria,COG2518@2|Bacteria,1GR5V@1117|Cyanobacteria	1117|Cyanobacteria	H	Glycosyl transferase family 11	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_11,Methyltransf_21
BYD2_k127_1589630_0	351607.Acel_2119	3.769e-319	996.0	COG0542@1|root,COG0542@2|Bacteria,2GJ73@201174|Actinobacteria,4ERET@85013|Frankiales	201174|Actinobacteria	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
BYD2_k127_1589630_19	1121918.ARWE01000001_gene1733	5.067e-56	217.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,42NB4@68525|delta/epsilon subdivisions,2WK9E@28221|Deltaproteobacteria,43VZY@69541|Desulfuromonadales	28221|Deltaproteobacteria	D	Chain length determinant protein	wzc2	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,ParA,Wzz
BYD2_k127_1589630_36	1380763.BG53_11520	1.132e-14	87.0	COG3307@1|root,COG3307@2|Bacteria	2|Bacteria	M	-O-antigen	-	-	-	ko:K02847,ko:K13009	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	9.B.67.4,9.B.67.5	-	-	Wzy_C
BYD2_k127_1589630_24	1133850.SHJG_6991	1.528e-40	173.0	COG2244@1|root,COG2244@2|Bacteria,2GJK0@201174|Actinobacteria	201174|Actinobacteria	A	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1589630_7	240015.ACP_0749	1.059e-141	473.0	COG0451@1|root,COG0451@2|Bacteria,3Y3J3@57723|Acidobacteria,2JIFZ@204432|Acidobacteriia	204432|Acidobacteriia	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
BYD2_k127_1589630_14	1380386.JIAW01000017_gene3184	1.239e-98	341.0	COG0707@1|root,COG0707@2|Bacteria,2I5NP@201174|Actinobacteria,238K6@1762|Mycobacteriaceae	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
BYD2_k127_1589630_18	996637.SGM_4868	1.489e-64	237.0	COG0297@1|root,COG0297@2|Bacteria,2I30C@201174|Actinobacteria	201174|Actinobacteria	G	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_1589630_20	1121946.AUAX01000006_gene3268	7.991e-54	205.0	COG0438@1|root,COG0438@2|Bacteria,2GM53@201174|Actinobacteria,4D8SV@85008|Micromonosporales	201174|Actinobacteria	M	PFAM glycosyl transferase group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_1589630_35	298653.Franean1_6542	2.592e-17	94.0	COG2148@1|root,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4ES81@85013|Frankiales	201174|Actinobacteria	M	PFAM sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
BYD2_k127_1589630_28	1229780.BN381_150053	1.336e-33	147.0	COG0789@1|root,COG0789@2|Bacteria,2IQJ4@201174|Actinobacteria,3UWU5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	hspR	GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K13640	-	-	-	-	ko00000,ko03000	-	-	-	MerR_1
BYD2_k127_1589630_10	525909.Afer_1962	2.379e-130	426.0	COG0484@1|root,COG0484@2|Bacteria,2GJKK@201174|Actinobacteria,4CMRG@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
BYD2_k127_1589630_30	1313172.YM304_39190	2.552e-31	143.0	COG0576@1|root,COG0576@2|Bacteria,2HGAI@201174|Actinobacteria,4CN9N@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
BYD2_k127_1589630_1	1229780.BN381_150056	3.025e-308	979.0	COG0443@1|root,COG0443@2|Bacteria,2GJTY@201174|Actinobacteria,3UW7G@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Heat shock 70 kDa protein	dnaK	GO:0000302,GO:0000303,GO:0000305,GO:0001968,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009893,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016310,GO:0019222,GO:0019538,GO:0019899,GO:0030112,GO:0030162,GO:0030312,GO:0030313,GO:0031323,GO:0031325,GO:0031975,GO:0031982,GO:0032268,GO:0032270,GO:0033554,GO:0034599,GO:0034614,GO:0035375,GO:0036211,GO:0040007,GO:0042221,GO:0042603,GO:0043170,GO:0043226,GO:0043227,GO:0043230,GO:0043388,GO:0043412,GO:0044044,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046677,GO:0046688,GO:0046777,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051099,GO:0051101,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070613,GO:0070887,GO:0071450,GO:0071451,GO:0071704,GO:0071944,GO:0080090,GO:0097691,GO:1901564,GO:1901700,GO:1901701,GO:1903317,GO:1903319,GO:1903561,GO:2000677,GO:2000679	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
BYD2_k127_1589630_16	1229780.BN381_70023	3.241e-82	278.0	COG0512@1|root,COG0512@2|Bacteria,2GJUX@201174|Actinobacteria,3UWPF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Peptidase C26	trpG	GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
BYD2_k127_1589630_26	102232.GLO73106DRAFT_00009580	1.602e-37	161.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
BYD2_k127_1589630_8	1229780.BN381_80138	6.578e-138	457.0	COG0248@1|root,COG0248@2|Bacteria,2GMME@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx1	GO:0003674,GO:0003824,GO:0006793,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0044237	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
BYD2_k127_1589630_32	1229780.BN381_70025	2.865e-24	110.0	28YVQ@1|root,2ZKNY@2|Bacteria,2HCMJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1589630_38	1108045.GORHZ_022_00020	4.605e-09	60.0	COG2936@1|root,COG2936@2|Bacteria,2IAA6@201174|Actinobacteria,4GA2U@85026|Gordoniaceae	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
BYD2_k127_1603996_2	1229780.BN381_100118	2.806e-69	241.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07340,ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,LprI,NfeD,SDH_sah
BYD2_k127_1603996_5	1229780.BN381_100117	2.585e-27	114.0	2CC1Y@1|root,32S23@2|Bacteria,2IQS5@201174|Actinobacteria,3UWYX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB3	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
BYD2_k127_1603996_6	1122609.AUGT01000003_gene2189	1.325e-25	112.0	COG3030@1|root,COG3030@2|Bacteria,2IA8V@201174|Actinobacteria,4DR8M@85009|Propionibacteriales	201174|Actinobacteria	S	FxsA cytoplasmic membrane protein	-	-	-	ko:K07113	-	-	-	-	ko00000	-	-	-	FxsA
BYD2_k127_1603996_1	1121374.KB891576_gene763	1.639e-72	263.0	COG0491@1|root,COG0491@2|Bacteria,1MVC3@1224|Proteobacteria,1S25T@1236|Gammaproteobacteria	1236|Gammaproteobacteria	L	COG0491 Zn-dependent hydrolases, including glyoxylases	blaB	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B,NUDIX
BYD2_k127_1603996_4	1380390.JIAT01000009_gene571	1.789e-39	166.0	COG0789@1|root,COG0789@2|Bacteria,2GKAU@201174|Actinobacteria,4CRRD@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
BYD2_k127_1603996_0	1313172.YM304_38460	7.123e-128	427.0	COG0489@1|root,COG2151@1|root,COG0489@2|Bacteria,COG2151@2|Bacteria,2H1YI@201174|Actinobacteria,4CNPI@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	-	-	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
BYD2_k127_1603996_3	1229780.BN381_100112	1.921e-47	173.0	COG2345@1|root,COG2345@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_1628776_20	1185652.USDA257_c50210	1.595e-25	112.0	COG0500@1|root,COG0500@2|Bacteria,1R2QQ@1224|Proteobacteria	1224|Proteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_1628776_0	1048339.KB913029_gene1969	0.0	1183.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
BYD2_k127_1628776_9	1048339.KB913029_gene1968	8.831e-125	417.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1628776_2	106370.Francci3_3865	1.825e-300	947.0	COG1217@1|root,COG1217@2|Bacteria,2GJUJ@201174|Actinobacteria,4ES8A@85013|Frankiales	201174|Actinobacteria	T	GTP-binding protein TypA	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2
BYD2_k127_1628776_14	1123320.KB889719_gene7198	2.884e-98	325.0	COG0778@1|root,COG0778@2|Bacteria,2I6AB@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_1628776_15	748280.NH8B_1828	3.871e-93	312.0	COG0778@1|root,COG0778@2|Bacteria,1MZN8@1224|Proteobacteria,2VI8R@28216|Betaproteobacteria,2KQQK@206351|Neisseriales	206351|Neisseriales	C	Nitroreductase family	-	-	1.13.11.79	ko:K04719	ko00740,ko01100,map00740,map01100	-	R09083	RC00435,RC02413	ko00000,ko00001,ko01000	-	-	-	Nitroreductase
BYD2_k127_1628776_16	477641.MODMU_2176	1.249e-67	240.0	COG0329@1|root,COG0329@2|Bacteria,2IM0E@201174|Actinobacteria	201174|Actinobacteria	EM	Dihydrodipicolinate synthetase family	-	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
BYD2_k127_1628776_6	479433.Caci_8740	2.429e-179	576.0	COG0318@1|root,COG0318@2|Bacteria,2GMVB@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1628776_11	1229780.BN381_330092	7.667e-115	375.0	COG0289@1|root,COG0289@2|Bacteria,2GM2T@201174|Actinobacteria,3UWJR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	-	DapB_C,DapB_N
BYD2_k127_1628776_4	219305.MCAG_02191	6.627e-184	591.0	COG0488@1|root,COG0488@2|Bacteria,2GK9S@201174|Actinobacteria,4DC7J@85008|Micromonosporales	201174|Actinobacteria	S	ATPases associated with a variety of cellular activities	yjjK	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
BYD2_k127_1628776_10	1449353.JQMQ01000005_gene1940	3.961e-115	391.0	COG0612@1|root,COG0612@2|Bacteria,2GJZ3@201174|Actinobacteria,2NGPG@228398|Streptacidiphilus	201174|Actinobacteria	S	Insulinase (Peptidase family M16)	pepR	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Peptidase_M16,Peptidase_M16_C
BYD2_k127_1628776_1	1313172.YM304_16080	2.355e-309	967.0	COG1185@1|root,COG1185@2|Bacteria,2GIT2@201174|Actinobacteria,4CMSF@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,S1
BYD2_k127_1628776_18	1313172.YM304_16070	5.205e-30	123.0	COG0184@1|root,COG0184@2|Bacteria,2IQA0@201174|Actinobacteria,4CNBM@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
BYD2_k127_1628776_12	1229780.BN381_330076	4.258e-104	355.0	COG1073@1|root,COG1073@2|Bacteria,2IB59@201174|Actinobacteria	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_1628776_13	1229780.BN381_330075	3.224e-101	339.0	COG0196@1|root,COG0196@2|Bacteria,2GKQF@201174|Actinobacteria,3UWJD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Riboflavin kinase	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
BYD2_k127_1628776_7	1229780.BN381_10099	7.561e-146	494.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,3UX4H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	metB	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.48	ko:K01739	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00999,R01288,R02508,R03217,R03260,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00420,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1079	Cys_Met_Meta_PP
BYD2_k127_1628776_5	1229780.BN381_10098	7.42e-184	586.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,3UWFV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cbs	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0016020,GO:0019842,GO:0030170,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071944,GO:0097159,GO:1901363	4.2.1.22	ko:K01697	ko00260,ko00270,ko01100,ko01130,ko01230,map00260,map00270,map01100,map01130,map01230	M00035,M00338	R00891,R01290,R04942	RC00056,RC00069,RC00256,RC00489,RC01246	ko00000,ko00001,ko00002,ko01000	-	-	-	CBS,PALP
BYD2_k127_1628776_8	235985.BBPN01000014_gene5539	1.1e-145	471.0	COG1902@1|root,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,2NEZW@228398|Streptacidiphilus	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.8.1.20	ko:K22347	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_FMN
BYD2_k127_1628776_17	1229780.BN381_330073	3.79e-64	240.0	COG0130@1|root,COG0130@2|Bacteria,2GJZK@201174|Actinobacteria,3UWK5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB_C,TruB_C_2,TruB_N
BYD2_k127_1628776_19	1313172.YM304_15980	9.001e-27	118.0	COG0858@1|root,COG0858@2|Bacteria,2HGGX@201174|Actinobacteria,4CNEB@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
BYD2_k127_1628776_21	1229780.BN381_330071	3.399e-20	97.0	COG1550@1|root,COG1550@2|Bacteria,2I1A0@201174|Actinobacteria,3UXQB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF503)	-	-	-	-	-	-	-	-	-	-	-	-	DUF503
BYD2_k127_1628776_3	1229780.BN381_330070	2.033e-214	674.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,3UW6W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
BYD2_k127_167546_2	643648.Slip_1472	3.995e-30	128.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,42K31@68298|Syntrophomonadaceae	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
BYD2_k127_167546_3	471852.Tcur_0908	1.591e-24	109.0	COG2331@1|root,COG2331@2|Bacteria,2IQHE@201174|Actinobacteria,4EKKD@85012|Streptosporangiales	201174|Actinobacteria	S	Putative regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
BYD2_k127_167546_0	632292.Calhy_1362	1.173e-89	309.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,42EWQ@68295|Thermoanaerobacterales	186801|Clostridia	F	Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage	mtaP	-	2.4.2.1,2.4.2.28	ko:K00772,ko:K03783	ko00230,ko00240,ko00270,ko00760,ko01100,ko01110,map00230,map00240,map00270,map00760,map01100,map01110	M00034	R01402,R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122,RC02819	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
BYD2_k127_167546_1	1313172.YM304_10970	4.66e-87	296.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
BYD2_k127_167546_4	1229780.BN381_90072	7.678e-23	100.0	COG0312@1|root,COG0312@2|Bacteria	2|Bacteria	S	metallopeptidase activity	pmbA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
BYD2_k127_1681604_4	446470.Snas_2214	2.609e-60	236.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EXWB@85014|Glycomycetales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
BYD2_k127_1681604_2	1313172.YM304_07710	1.908e-81	282.0	COG0581@1|root,COG0581@2|Bacteria,2I2F2@201174|Actinobacteria	201174|Actinobacteria	P	phosphate transport system permease	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
BYD2_k127_1681604_0	1313172.YM304_07700	1.262e-100	338.0	COG0573@1|root,COG0573@2|Bacteria,2GJDA@201174|Actinobacteria	201174|Actinobacteria	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
BYD2_k127_1681604_1	1313172.YM304_07690	3.368e-99	344.0	COG0226@1|root,COG0226@2|Bacteria,2GMY1@201174|Actinobacteria	201174|Actinobacteria	P	phosphate binding protein	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	HSP70,PBP_like,PBP_like_2
BYD2_k127_1681604_6	1074488.AGBX01000001_gene387	2.232e-35	140.0	COG0406@1|root,COG1051@1|root,COG0406@2|Bacteria,COG1051@2|Bacteria,2I2N2@201174|Actinobacteria,4FBKV@85020|Dermabacteraceae	201174|Actinobacteria	FG	Phosphoglycerate mutase family	mutT	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
BYD2_k127_1681604_3	580340.Tlie_0063	2.731e-77	285.0	COG1322@1|root,COG1322@2|Bacteria,3T9XJ@508458|Synergistetes	508458|Synergistetes	S	PFAM RmuC family	-	-	-	ko:K09760	-	-	-	-	ko00000	-	-	-	RmuC
BYD2_k127_1681604_5	1229780.BN381_130089	1.08e-50	184.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,3UWBN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
BYD2_k127_1703535_10	877455.Metbo_1812	1.56e-63	222.0	COG1704@1|root,arCOG04574@2157|Archaea,2XXB9@28890|Euryarchaeota,23PHV@183925|Methanobacteria	183925|Methanobacteria	S	PFAM LemA	-	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
BYD2_k127_1703535_3	1313172.YM304_19800	7.6e-111	366.0	COG0501@1|root,COG0501@2|Bacteria,2GMJF@201174|Actinobacteria,4CNA7@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Peptidase family M48	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
BYD2_k127_1703535_2	1313172.YM304_19820	2.011e-145	465.0	COG0214@1|root,COG0214@2|Bacteria,2GK1T@201174|Actinobacteria,4CMSX@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
BYD2_k127_1703535_16	43354.JOIJ01000001_gene396	6.601e-14	86.0	COG3147@1|root,COG3147@2|Bacteria,2GYC2@201174|Actinobacteria,4ECZ4@85010|Pseudonocardiales	201174|Actinobacteria	S	Non-essential cell division protein that could be required for efficient cell constriction	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1703535_11	1123023.JIAI01000029_gene4439	1.611e-63	223.0	COG0311@1|root,COG0311@2|Bacteria,2GNYG@201174|Actinobacteria,4DXHN@85010|Pseudonocardiales	201174|Actinobacteria	H	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS	pdxT	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SNO
BYD2_k127_1703535_5	1229780.BN381_50101	1.134e-100	333.0	COG0217@1|root,COG0217@2|Bacteria,2GJ4G@201174|Actinobacteria,3UWE9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Transcriptional regulator	yebC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
BYD2_k127_1703535_14	1313172.YM304_19850	1.747e-49	185.0	COG1225@1|root,COG1225@2|Bacteria,2IJVV@201174|Actinobacteria,4CN6R@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Redoxin	-	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
BYD2_k127_1703535_15	1229780.BN381_50108	1.552e-46	173.0	COG0817@1|root,COG0817@2|Bacteria,2GJI5@201174|Actinobacteria,3UWKV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group	ruvC	GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576	3.1.22.4	ko:K01159	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvC
BYD2_k127_1703535_13	1229780.BN381_50109	3.476e-52	199.0	COG0632@1|root,COG0632@2|Bacteria,2GN17@201174|Actinobacteria,3UWUJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
BYD2_k127_1703535_1	1313172.YM304_19880	1.259e-147	488.0	COG2255@1|root,COG2255@2|Bacteria,2GJZF@201174|Actinobacteria,4CMVN@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
BYD2_k127_1703535_7	1313172.YM304_19900	1.788e-99	337.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,4CMRE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
BYD2_k127_1703535_4	1121861.KB899923_gene3419	9.005e-108	362.0	COG0343@1|root,COG0343@2|Bacteria,1MUCA@1224|Proteobacteria,2TR87@28211|Alphaproteobacteria,2JPNV@204441|Rhodospirillales	204441|Rhodospirillales	J	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
BYD2_k127_1703535_17	1123229.AUBC01000017_gene3851	5.803e-10	68.0	COG1862@1|root,COG1862@2|Bacteria,1MZT2@1224|Proteobacteria,2UBZ6@28211|Alphaproteobacteria,3JYU5@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	U	Preprotein translocase subunit	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
BYD2_k127_1703535_6	1313172.YM304_19930	1.606e-99	347.0	COG0342@1|root,COG0342@2|Bacteria,2GJTT@201174|Actinobacteria,4CMXX@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
BYD2_k127_1703535_9	1894.JOER01000023_gene7344	4.578e-72	276.0	COG0341@1|root,COG0341@2|Bacteria,2GJRS@201174|Actinobacteria	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secF	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944	-	ko:K03072,ko:K03074	ko03060,ko03070,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
BYD2_k127_1703535_12	1313172.YM304_19950	4.942e-57	211.0	COG0503@1|root,COG0503@2|Bacteria,2IM7C@201174|Actinobacteria	201174|Actinobacteria	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	GO:0003674,GO:0003824,GO:0003999,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006144,GO:0006168,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009113,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
BYD2_k127_1703535_0	1313172.YM304_19960	0.0	1009.0	COG0317@1|root,COG0317@2|Bacteria,2GJYQ@201174|Actinobacteria,4CMVH@84992|Acidimicrobiia	84992|Acidimicrobiia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	ACT_4,HD_4,RelA_SpoT,TGS
BYD2_k127_1703535_8	864702.OsccyDRAFT_3484	3.612e-89	314.0	COG3266@1|root,COG3391@1|root,COG3266@2|Bacteria,COG3391@2|Bacteria,1G33X@1117|Cyanobacteria,1H9RN@1150|Oscillatoriales	1117|Cyanobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_D1,PG_binding_1
BYD2_k127_1726079_12	47839.CCAU010000009_gene1857	6.269e-96	320.0	COG4638@1|root,COG4638@2|Bacteria,2GM3P@201174|Actinobacteria,233JP@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
BYD2_k127_1726079_9	1193181.BN10_690004	6.929e-108	358.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4FFNS@85021|Intrasporangiaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_1726079_5	298654.FraEuI1c_3329	1.596e-180	581.0	COG0318@1|root,COG0318@2|Bacteria,2IEKP@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_1726079_3	298654.FraEuI1c_3330	8.427e-186	616.0	COG2030@1|root,COG2030@2|Bacteria	2|Bacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
BYD2_k127_1726079_14	365528.KB891224_gene1384	2.717e-19	98.0	2F365@1|root,33W0Q@2|Bacteria,2H4WA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	EthD
BYD2_k127_1726079_6	365528.KB891181_gene4715	1.729e-168	544.0	COG1014@1|root,COG4231@1|root,COG1014@2|Bacteria,COG4231@2|Bacteria,2GKBW@201174|Actinobacteria	201174|Actinobacteria	C	indolepyruvate ferredoxin oxidoreductase	-	-	1.2.7.8	ko:K00179,ko:K04090	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR,POR_N,TPP_enzyme_C
BYD2_k127_1726079_2	298653.Franean1_6850	4.244e-200	630.0	COG1960@1|root,COG1960@2|Bacteria,2GP53@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_1726079_10	298654.FraEuI1c_5490	2.018e-105	370.0	COG1960@1|root,COG1960@2|Bacteria,2GIXH@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
BYD2_k127_1726079_1	547163.BN979_04853	6.683e-202	642.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,235CF@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_1726079_11	222534.KB893720_gene829	6.837e-97	328.0	COG1960@1|root,COG1960@2|Bacteria,2GM4S@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
BYD2_k127_1726079_0	298654.FraEuI1c_5487	1.529e-243	755.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_1726079_13	1206720.BAFQ01000053_gene1363	4.486e-23	104.0	COG1141@1|root,COG1141@2|Bacteria,2GWHY@201174|Actinobacteria,4G4BS@85025|Nocardiaceae	201174|Actinobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
BYD2_k127_1726079_8	1380390.JIAT01000012_gene3099	3.367e-108	372.0	COG3324@1|root,COG3324@2|Bacteria,2GJFC@201174|Actinobacteria,4CU3N@84995|Rubrobacteria	84995|Rubrobacteria	S	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1726079_4	477641.MODMU_1976	1.664e-185	627.0	COG1474@1|root,COG2909@1|root,COG1474@2|Bacteria,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_1726079_16	1283283.ATXA01000001_gene316	2.798e-16	93.0	COG3631@1|root,COG3631@2|Bacteria,2IQ1R@201174|Actinobacteria	201174|Actinobacteria	S	Ketosteroid isomerase-related protein	-	-	-	ko:K06893	-	-	-	-	ko00000	-	-	-	SnoaL_2
BYD2_k127_1726079_15	1283283.ATXA01000004_gene4371	1.468e-16	91.0	COG1028@1|root,COG1028@2|Bacteria,2I8XB@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_1726079_17	1120949.KB903294_gene3521	1.899e-05	56.0	COG1028@1|root,COG1028@2|Bacteria,2I8XB@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_1726079_7	485913.Krac_5346	3.51e-148	487.0	COG0492@1|root,COG0492@2|Bacteria,2G5Z5@200795|Chloroflexi	2|Bacteria	C	FAD-dependent pyridine nucleotide-disulphide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,cNMP_binding
BYD2_k127_1729102_1	345341.KUTG_04476	5.243e-40	150.0	COG0642@1|root,COG2205@2|Bacteria,2I3JI@201174|Actinobacteria,4DYM4@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BYD2_k127_1729102_0	1121926.AXWO01000008_gene2920	1.831e-123	410.0	COG0451@1|root,COG0451@2|Bacteria,2GK8K@201174|Actinobacteria,4EZBG@85014|Glycomycetales	201174|Actinobacteria	M	Polysaccharide biosynthesis protein	galE3	-	5.1.3.25	ko:K17947	ko00523,ko01130,map00523,map01130	-	R10279	RC00289	ko00000,ko00001,ko01000	-	-	-	Epimerase
BYD2_k127_1729102_2	1121385.AQXW01000002_gene101	2.16e-19	91.0	28KB1@1|root,2Z9Y5@2|Bacteria,2GM37@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1737017_1	710687.KI912270_gene2052	4.061e-73	265.0	COG2321@1|root,COG2321@2|Bacteria,2HBKZ@201174|Actinobacteria,235R2@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative neutral zinc metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zn_peptidase
BYD2_k127_1737017_0	1229780.BN381_330074	5.167e-196	642.0	COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,3UX4U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
BYD2_k127_1737017_2	1229780.BN381_80379	3.749e-17	82.0	COG1960@1|root,COG1960@2|Bacteria,2GJ7S@201174|Actinobacteria,3UX8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_1756760_3	329726.AM1_5320	2.302e-82	285.0	COG2146@1|root,COG2146@2|Bacteria,1G2KG@1117|Cyanobacteria	1117|Cyanobacteria	P	nitrite reductase [NAD(P)H] activity	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Rieske_2
BYD2_k127_1756760_4	266117.Rxyl_1743	1.024e-81	296.0	COG0842@1|root,COG0842@2|Bacteria,2IPQ3@201174|Actinobacteria,4CT8V@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_1756760_1	42256.RradSPS_0764	4.622e-124	406.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4CP6S@84995|Rubrobacteria	84995|Rubrobacteria	V	Daunorubicin resistance ABC transporter ATP-binding subunit	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_1756760_6	469383.Cwoe_3583	8.187e-71	244.0	COG0262@1|root,COG0262@2|Bacteria,2GK32@201174|Actinobacteria	201174|Actinobacteria	H	Dihydrofolate reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_1756760_8	926550.CLDAP_05840	1.235e-12	81.0	COG0457@1|root,COG4995@1|root,COG0457@2|Bacteria,COG4995@2|Bacteria,2G903@200795|Chloroflexi	200795|Chloroflexi	S	CHAT domain	-	-	-	-	-	-	-	-	-	-	-	-	CHAT
BYD2_k127_1756760_7	1380346.JNIH01000004_gene2421	1.506e-38	149.0	COG5015@1|root,COG5015@2|Bacteria,2GPHG@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07006	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
BYD2_k127_1756760_0	469371.Tbis_1574	0.0	1401.0	COG0507@1|root,COG1112@1|root,COG2852@1|root,COG0507@2|Bacteria,COG1112@2|Bacteria,COG2852@2|Bacteria,2HI92@201174|Actinobacteria,4DXAQ@85010|Pseudonocardiales	201174|Actinobacteria	L	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	-	-	-	-	-	-	-	-	-	AAA_11,AAA_12
BYD2_k127_1756760_2	1382303.JPOM01000001_gene2362	1.503e-82	279.0	COG4341@1|root,COG4341@2|Bacteria,1QHQD@1224|Proteobacteria,2U1W2@28211|Alphaproteobacteria,2KHXP@204458|Caulobacterales	204458|Caulobacterales	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	-	-	-	-	-	-	-	-	-	HD
BYD2_k127_1756760_5	164757.Mjls_2215	5.211e-71	256.0	COG3832@1|root,COG3832@2|Bacteria,2IHQ1@201174|Actinobacteria,238XQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_1764593_5	446470.Snas_1183	3.007e-38	143.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4EY5Q@85014|Glycomycetales	201174|Actinobacteria	J	Elongation factor Tu C-terminal domain	tuf	GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0019899,GO:0030312,GO:0035375,GO:0036293,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
BYD2_k127_1764593_8	525909.Afer_0383	9.062e-19	86.0	COG0267@1|root,COG0267@2|Bacteria,2HH2Z@201174|Actinobacteria,4CP34@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L33	-	-	-	ko:K02913	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L33
BYD2_k127_1764593_2	1229780.BN381_610018	1.376e-59	214.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,3UXIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_1764593_4	1121106.JQKB01000162_gene6108	5.916e-50	184.0	COG5553@1|root,COG5553@2|Bacteria,1RD6A@1224|Proteobacteria,2U7HF@28211|Alphaproteobacteria,2JVV3@204441|Rhodospirillales	204441|Rhodospirillales	S	of the double-stranded beta helix	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1764593_10	207954.MED92_04552	0.0002478	46.0	COG0690@1|root,COG0690@2|Bacteria,1RDI9@1224|Proteobacteria,1S3PA@1236|Gammaproteobacteria,1XKF5@135619|Oceanospirillales	135619|Oceanospirillales	U	Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
BYD2_k127_1764593_9	1229780.BN381_350057	1.784e-17	91.0	COG0690@1|root,COG0690@2|Bacteria	2|Bacteria	U	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	secE	GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
BYD2_k127_1764593_1	1229780.BN381_350058	5.043e-86	295.0	COG0250@1|root,COG0250@2|Bacteria,2GJFW@201174|Actinobacteria,3UWJ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in transcription elongation, termination and antitermination	nusG	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1903506,GO:2000112,GO:2001141	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusG
BYD2_k127_1764593_3	1229780.BN381_350060	1.36e-58	213.0	COG0080@1|root,COG0080@2|Bacteria,2IFCK@201174|Actinobacteria,3UWIZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
BYD2_k127_1764593_0	1313172.YM304_07900	1.501e-102	339.0	COG0081@1|root,COG0081@2|Bacteria,2GM51@201174|Actinobacteria,4CMU4@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
BYD2_k127_1764593_7	1123023.JIAI01000015_gene3302	2.352e-30	123.0	COG0244@1|root,COG0244@2|Bacteria,2GM0V@201174|Actinobacteria,4E0K2@85010|Pseudonocardiales	201174|Actinobacteria	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
BYD2_k127_176689_11	1313172.YM304_38450	1.029e-48	180.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_176689_13	525909.Afer_0240	2.828e-35	137.0	COG0316@1|root,COG0316@2|Bacteria,2IHR0@201174|Actinobacteria,4CN53@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Iron-sulphur cluster biosynthesis	erpA	-	-	ko:K13628	-	-	-	-	ko00000,ko03016	-	-	-	Fe-S_biosyn
BYD2_k127_176689_1	35754.JNYJ01000046_gene3102	1.536e-172	564.0	COG1520@1|root,COG1520@2|Bacteria,2I9S4@201174|Actinobacteria,4D97G@85008|Micromonosporales	201174|Actinobacteria	S	beta-propeller repeat	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
BYD2_k127_176689_2	1313172.YM304_38400	5.103e-160	539.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria	2|Bacteria	C	2 iron, 2 sulfur cluster binding	xdh	-	1.17.1.4,1.2.5.3,1.3.99.16	ko:K00087,ko:K03518,ko:K07302	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103,R11168	RC00143,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
BYD2_k127_176689_14	1313172.YM304_38390	2.331e-28	131.0	COG0251@1|root,COG0251@2|Bacteria	2|Bacteria	J	oxidation-reduction process	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
BYD2_k127_176689_4	1521187.JPIM01000046_gene1463	5.171e-114	392.0	COG1178@1|root,COG1178@2|Bacteria,2G5Q0@200795|Chloroflexi,375FG@32061|Chloroflexia	32061|Chloroflexia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
BYD2_k127_176689_7	1385515.N791_14575	3.677e-77	271.0	COG1840@1|root,COG1840@2|Bacteria,1MUEG@1224|Proteobacteria,1RQ6Z@1236|Gammaproteobacteria,1X3B1@135614|Xanthomonadales	135614|Xanthomonadales	P	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_6
BYD2_k127_176689_6	266117.Rxyl_1173	2.025e-88	303.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4CRCY@84995|Rubrobacteria	201174|Actinobacteria	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
BYD2_k127_176689_10	1380390.JIAT01000014_gene6287	1.827e-52	203.0	COG1807@1|root,COG1807@2|Bacteria,2HJTU@201174|Actinobacteria,4CPVS@84995|Rubrobacteria	84995|Rubrobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_176689_9	575540.Isop_0600	2.772e-60	220.0	COG1216@1|root,COG1216@2|Bacteria,2IZFD@203682|Planctomycetes	203682|Planctomycetes	M	Glycosyl transferase family 21	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_176689_15	1206735.BAGG01000093_gene3864	1.024e-09	72.0	COG0673@1|root,COG0673@2|Bacteria,2GJCY@201174|Actinobacteria,4FWPA@85025|Nocardiaceae	201174|Actinobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
BYD2_k127_176689_8	1089551.KE386572_gene4426	3.946e-63	235.0	COG3379@1|root,COG3379@2|Bacteria,1NBJ6@1224|Proteobacteria,2U12I@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
BYD2_k127_176689_12	1247963.JPHU01000002_gene2496	2.161e-41	177.0	COG1216@1|root,COG1216@2|Bacteria,1R5GW@1224|Proteobacteria,2TTEN@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_trans_2_3,Glycos_transf_2
BYD2_k127_176689_5	1313172.YM304_38350	4.889e-90	301.0	COG0745@1|root,COG0745@2|Bacteria,2GJGU@201174|Actinobacteria,4CN27@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
BYD2_k127_176689_0	1313172.YM304_38340	4.68e-193	614.0	COG0174@1|root,COG0174@2|Bacteria,2GJ2I@201174|Actinobacteria,4CMV7@84992|Acidimicrobiia	84992|Acidimicrobiia	E	glutamine synthetase	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
BYD2_k127_176689_3	134676.ACPL_2404	6.201e-153	486.0	COG0174@1|root,COG0174@2|Bacteria,2GKU9@201174|Actinobacteria,4DH1U@85008|Micromonosporales	201174|Actinobacteria	E	Glutamine synthetase, beta-Grasp domain	glnII	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
BYD2_k127_1769474_11	649831.L083_5787	8.227e-09	69.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
BYD2_k127_1769474_1	1229780.BN381_330109	5.204e-214	690.0	COG0423@1|root,COG0423@2|Bacteria,2GIT3@201174|Actinobacteria,3UW9K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
BYD2_k127_1769474_5	1121385.AQXW01000003_gene561	9.21e-79	281.0	COG2232@1|root,COG2232@2|Bacteria,2IDDC@201174|Actinobacteria,1ZWHS@145357|Dermacoccaceae	201174|Actinobacteria	S	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1769474_9	211165.AJLN01000149_gene6671	2.747e-29	123.0	COG1846@1|root,COG1846@2|Bacteria,1G8MU@1117|Cyanobacteria,1JM1T@1189|Stigonemataceae	1117|Cyanobacteria	K	Sugar-specific transcriptional regulator TrmB	-	-	-	-	-	-	-	-	-	-	-	-	MarR
BYD2_k127_1769474_0	479434.Sthe_2199	1.401e-257	814.0	COG2409@1|root,COG2409@2|Bacteria,2G6XZ@200795|Chloroflexi,27XX9@189775|Thermomicrobia	200795|Chloroflexi	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_1769474_10	1033736.CAHK01000033_gene1138	9.512e-18	97.0	COG0216@1|root,COG0216@2|Bacteria,2I7Z4@201174|Actinobacteria,4FA81@85019|Brevibacteriaceae	201174|Actinobacteria	J	RF-1 domain	-	-	-	ko:K15034	-	-	-	-	ko00000,ko03012	-	-	-	RF-1
BYD2_k127_1769474_4	479435.Kfla_5629	5.949e-83	295.0	COG0842@1|root,COG0842@2|Bacteria,2GMXR@201174|Actinobacteria,4DNU1@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
BYD2_k127_1769474_6	1122138.AQUZ01000003_gene399	1.837e-63	231.0	COG0842@1|root,COG0842@2|Bacteria,2GVC2@201174|Actinobacteria,4DQNH@85009|Propionibacteriales	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K09694	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC2_membrane
BYD2_k127_1769474_2	1120934.KB894413_gene3437	9.269e-133	431.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4E0JW@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC transporter	nodI	-	-	ko:K09695	ko02010,map02010	M00252	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.102	-	-	ABC_tran
BYD2_k127_1769474_8	211114.JOEF01000006_gene2571	8.83e-43	160.0	COG4954@1|root,COG4954@2|Bacteria,2IFBK@201174|Actinobacteria,4E3QH@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2000
BYD2_k127_1769474_3	675635.Psed_4541	1.402e-89	306.0	COG2207@1|root,COG2207@2|Bacteria,2GNEB@201174|Actinobacteria,4DY9K@85010|Pseudonocardiales	201174|Actinobacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
BYD2_k127_1769474_7	326424.FRAAL3575	2.267e-56	207.0	2A84P@1|root,30X5E@2|Bacteria,2IN6P@201174|Actinobacteria,4EWIK@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1782366_1	1229780.BN381_640025	6.154e-68	246.0	COG2856@1|root,COG2856@2|Bacteria,2GPBB@201174|Actinobacteria	201174|Actinobacteria	E	Zn peptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1782366_0	1229780.BN381_290057	3.079e-95	337.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,3UXH6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_1782366_2	1206732.BAGD01000074_gene2939	1.988e-62	227.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4G63V@85025|Nocardiaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_1782366_3	1078020.KEK_19426	7.549e-05	48.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2GJTZ@201174|Actinobacteria,2335I@1762|Mycobacteriaceae	201174|Actinobacteria	V	ABC-type transport system, involved in lipoprotein release, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_1799993_2	1394178.AWOO02000046_gene6491	1.357e-18	88.0	2E4G6@1|root,32ZBB@2|Bacteria,2GR6E@201174|Actinobacteria,4EKH1@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1799993_4	557599.MKAN_29125	5.872e-07	55.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria,23B9T@1762|Mycobacteriaceae	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_1799993_1	557599.MKAN_29150	5.466e-50	193.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,235YM@1762|Mycobacteriaceae	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_1799993_0	1229780.BN381_40088	1.611e-108	353.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,3UWJC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
BYD2_k127_1799993_3	1489678.RDMS_11420	8.817e-10	66.0	COG0229@1|root,COG0229@2|Bacteria,1WMZM@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	O	methionine sulfoxide reductase	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
BYD2_k127_18110_0	1313172.YM304_27360	1.706e-167	535.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMUC@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
BYD2_k127_18110_1	953739.SVEN_5039	1.438e-96	321.0	COG1637@1|root,COG1637@2|Bacteria,2GIYB@201174|Actinobacteria	201174|Actinobacteria	L	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures	nucS	-	-	ko:K07503	-	-	-	-	ko00000,ko01000	-	-	-	NucS
BYD2_k127_18110_2	1229780.BN381_10281	4.569e-36	138.0	COG2030@1|root,COG2030@2|Bacteria,2GJJI@201174|Actinobacteria,3UXJQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	htdY	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
BYD2_k127_1829474_2	1229780.BN381_250079	3.722e-91	305.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,3UWJK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	FAD_oxidored,Oxidored_FMN,Pyr_redox_2
BYD2_k127_1829474_3	882083.SacmaDRAFT_1199	7.492e-78	281.0	COG2025@1|root,COG2025@2|Bacteria,2IIKX@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein alpha subunit	-	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
BYD2_k127_1829474_0	1229780.BN381_250065	7.012e-176	560.0	COG0644@1|root,COG0644@2|Bacteria	2|Bacteria	C	geranylgeranyl reductase activity	-	-	-	ko:K00313	-	-	-	-	ko00000,ko01000	-	-	-	DAO,FAD_binding_3,FAD_oxidored,Pyr_redox_2
BYD2_k127_1829474_7	298655.KI912266_gene2255	3.386e-44	180.0	COG2440@1|root,COG2440@2|Bacteria,2IREY@201174|Actinobacteria	201174|Actinobacteria	C	Psort location Cytoplasmic, score	fixX	-	-	ko:K03855	-	-	-	-	ko00000	-	-	-	ETF_QO
BYD2_k127_1829474_6	994479.GL877879_gene5204	4.957e-50	190.0	COG2086@1|root,COG2086@2|Bacteria,2GSWB@201174|Actinobacteria	201174|Actinobacteria	C	Electron transfer flavoprotein	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
BYD2_k127_1829474_4	656024.FsymDg_2777	2.174e-75	268.0	COG1402@1|root,COG1402@2|Bacteria,2HCRK@201174|Actinobacteria,4ESNU@85013|Frankiales	201174|Actinobacteria	S	PFAM Creatininase	mftE	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
BYD2_k127_1829474_5	1229780.BN381_250061	3.755e-73	269.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
BYD2_k127_1829474_1	882083.SacmaDRAFT_1194	2.71e-112	387.0	COG1215@1|root,COG1215@2|Bacteria,2I4CF@201174|Actinobacteria,4EFEH@85010|Pseudonocardiales	201174|Actinobacteria	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_1908862_0	298654.FraEuI1c_4139	0.0	1092.0	COG0411@1|root,COG0559@1|root,COG4177@1|root,COG0411@2|Bacteria,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria,4EU9I@85013|Frankiales	201174|Actinobacteria	P	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
BYD2_k127_1908862_1	298653.Franean1_2697	8.733e-110	370.0	COG0683@1|root,COG0683@2|Bacteria,2IB96@201174|Actinobacteria	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
BYD2_k127_1908862_2	298654.FraEuI1c_5456	2.491e-72	246.0	COG0183@1|root,COG0183@2|Bacteria,2GKWR@201174|Actinobacteria,4ES3R@85013|Frankiales	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_1927323_1	1121272.KB903290_gene4739	4.611e-26	124.0	2A18G@1|root,30PEU@2|Bacteria,2IGED@201174|Actinobacteria,4DD94@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1927323_0	290397.Adeh_1181	3.381e-38	145.0	COG1573@1|root,COG1573@2|Bacteria,1MW8T@1224|Proteobacteria,42ZZ6@68525|delta/epsilon subdivisions,2WV5A@28221|Deltaproteobacteria	28221|Deltaproteobacteria	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
BYD2_k127_1932275_6	909613.UO65_2799	1.797e-54	194.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DXQ2@85010|Pseudonocardiales	201174|Actinobacteria	G	Alpha amylase, catalytic domain	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,3.2.1.20,5.4.99.16	ko:K01187,ko:K05343	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R01557,R02108,R02112,R06087,R06088,R11262	RC00028,RC00049,RC00077,RC01816	ko00000,ko00001,ko01000	-	GH13,GH31	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
BYD2_k127_1932275_1	565045.NOR51B_1530	2.268e-162	522.0	COG0620@1|root,COG0620@2|Bacteria,1QJ82@1224|Proteobacteria,1TH64@1236|Gammaproteobacteria,1J9IH@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	E	E COG0620 Methionine synthase II (cobalamin-independent)	-	-	-	-	-	-	-	-	-	-	-	-	Meth_synt_2
BYD2_k127_1932275_3	1449353.JQMQ01000005_gene499	4.885e-85	289.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,2NHGV@228398|Streptacidiphilus	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_1932275_5	1116232.AHBF01000077_gene8164	3.253e-55	206.0	COG0596@1|root,COG0596@2|Bacteria,2I5IJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_1932275_4	208444.JNYY01000001_gene5067	8.063e-80	293.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4DZJ6@85010|Pseudonocardiales	201174|Actinobacteria	K	TIGRFAM beta-ketoadipate pathway transcriptional regulators, PcaR PcaU PobR family	-	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
BYD2_k127_1932275_0	1298880.AUEV01000011_gene2658	8.775e-165	542.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
BYD2_k127_1932275_2	35754.JNYJ01000062_gene1459	3.766e-105	347.0	COG0372@1|root,COG0372@2|Bacteria,2H9YP@201174|Actinobacteria,4D8JE@85008|Micromonosporales	201174|Actinobacteria	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
BYD2_k127_1943604_0	1121877.JQKF01000045_gene1208	1.174e-195	646.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,4CMU8@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
BYD2_k127_1943604_1	1313172.YM304_19970	1.654e-136	446.0	COG0124@1|root,COG0124@2|Bacteria,2GIYJ@201174|Actinobacteria,4CNBR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Histidyl-tRNA synthetase	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_His
BYD2_k127_1943604_2	1313172.YM304_06320	8.084e-08	56.0	2DCWG@1|root,2ZFKS@2|Bacteria	2|Bacteria	S	CsbD-like	-	-	-	-	-	-	-	-	-	-	-	-	CsbD
BYD2_k127_1947725_7	2002.JOEQ01000014_gene5283	4.433e-91	317.0	COG1232@1|root,COG1232@2|Bacteria,2GMMA@201174|Actinobacteria,4EFNQ@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX	hemG	-	1.3.3.15,1.3.3.4	ko:K00231	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03222,R04178	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
BYD2_k127_1947725_14	1313172.YM304_09330	9.301e-35	153.0	COG3764@1|root,COG3764@2|Bacteria	2|Bacteria	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
BYD2_k127_1947725_10	1193181.BN10_1030008	4.256e-72	261.0	COG5542@1|root,COG5542@2|Bacteria,2HXZR@201174|Actinobacteria,4FIWN@85021|Intrasporangiaceae	201174|Actinobacteria	S	Mannosyltransferase (PIG-V)	-	-	-	-	-	-	-	-	-	-	-	-	Mannosyl_trans2
BYD2_k127_1947725_3	1229780.BN381_100020	1.974e-116	392.0	COG0815@1|root,COG0815@2|Bacteria,2GJ9F@201174|Actinobacteria,3UWR9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Transfers the fatty acyl group on membrane lipoproteins	lnt	-	-	ko:K03820	-	-	-	-	ko00000,ko01000	-	GT2	-	CN_hydrolase
BYD2_k127_1947725_13	1463887.KL590006_gene2516	3.081e-50	184.0	COG1490@1|root,COG1490@2|Bacteria,2IKVR@201174|Actinobacteria	201174|Actinobacteria	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
BYD2_k127_1947725_12	1123023.JIAI01000005_gene659	1.186e-52	212.0	COG0443@1|root,COG0443@2|Bacteria,2GNTE@201174|Actinobacteria,4E043@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
BYD2_k127_1947725_0	1229780.BN381_150118	4.782e-178	567.0	COG0438@1|root,COG0438@2|Bacteria,2GMXE@201174|Actinobacteria,3UX6F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_1947725_9	1298863.AUEP01000012_gene3789	2.277e-85	309.0	COG0500@1|root,COG2226@2|Bacteria,2H38T@201174|Actinobacteria,4DPDW@85009|Propionibacteriales	201174|Actinobacteria	Q	Mycolic acid cyclopropane synthetase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_1947725_1	1229780.BN381_150116	7.597e-142	477.0	COG3387@1|root,COG3387@2|Bacteria,2GKU7@201174|Actinobacteria,3UX92@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Prenyltrans
BYD2_k127_1947725_11	1463857.JOFZ01000009_gene6303	6.465e-62	230.0	COG1672@1|root,COG1672@2|Bacteria,2GMAZ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Archaeal ATPase	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
BYD2_k127_1947725_8	1313172.YM304_09090	2.933e-90	303.0	COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria,4CN8Q@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
BYD2_k127_1947725_6	1242864.D187_003353	1.996e-93	323.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,42NU4@68525|delta/epsilon subdivisions,2WKV0@28221|Deltaproteobacteria,2YVPN@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
BYD2_k127_1947725_2	1077972.ARGLB_116_00640	3.39e-117	404.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 1 family	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
BYD2_k127_1947725_5	525909.Afer_1834	5.794e-110	362.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,4CMRR@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Thioesterase-like superfamily	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
BYD2_k127_1947725_4	67281.JNZZ01000016_gene6115	2.812e-112	376.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,41AW1@629295|Streptomyces griseus group	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
BYD2_k127_1947725_16	1283299.AUKG01000001_gene1283	4.184e-20	96.0	COG3502@1|root,COG3502@2|Bacteria,2HTYI@201174|Actinobacteria,4CTAB@84995|Rubrobacteria	84995|Rubrobacteria	S	Protein of unknown function (DUF952)	-	-	-	-	-	-	-	-	-	-	-	-	DUF952
BYD2_k127_1947725_15	411483.FAEPRAA2165_00109	2.929e-30	132.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3WGGT@541000|Ruminococcaceae	186801|Clostridia	J	Methylates ribosomal protein L11	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
BYD2_k127_1951118_4	1385519.N801_14600	1.443e-64	230.0	COG0262@1|root,COG0262@2|Bacteria,2GJU5@201174|Actinobacteria,4FJID@85021|Intrasporangiaceae	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_1951118_2	37919.EP51_00200	8.039e-76	259.0	COG1309@1|root,COG1309@2|Bacteria,2IFH9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_1951118_1	37919.EP51_00195	1.465e-150	492.0	COG0654@1|root,COG0654@2|Bacteria,2GKUZ@201174|Actinobacteria,4FYKD@85025|Nocardiaceae	201174|Actinobacteria	CH	FAD binding domain	sppF	-	1.14.13.200	ko:K14672,ko:K15972	ko01057,ko01130,map01057,map01130	M00783	R06704,R10954	RC02681	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	FAD_binding_3
BYD2_k127_1951118_6	1385519.N801_15030	6.771e-46	169.0	COG0572@1|root,COG0572@2|Bacteria,2I5X2@201174|Actinobacteria,4FJI0@85021|Intrasporangiaceae	201174|Actinobacteria	F	uridine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1951118_0	1120950.KB892776_gene796	1.117e-179	571.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4DP99@85009|Propionibacteriales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
BYD2_k127_1951118_3	1128421.JAGA01000004_gene2699	5.139e-69	250.0	COG0384@1|root,COG0384@2|Bacteria,2NR2U@2323|unclassified Bacteria	2|Bacteria	S	Phenazine biosynthesis-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PhzC-PhzF
BYD2_k127_1951118_5	1123024.AUII01000028_gene2518	1.419e-57	211.0	COG0406@1|root,COG0406@2|Bacteria,2HRP2@201174|Actinobacteria,4EAZ6@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
BYD2_k127_1951118_7	1313172.YM304_18970	7.461e-21	95.0	2C2HI@1|root,345RC@2|Bacteria,2H8AE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1968886_0	1229780.BN381_140013	7.304e-112	385.0	COG0768@1|root,COG0768@2|Bacteria,2GKHH@201174|Actinobacteria,3UWG5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Penicillin-binding Protein dimerisation domain	ftsI	-	3.4.16.4	ko:K03587	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PBP_dimer,Transpeptidase
BYD2_k127_1972567_3	471852.Tcur_2404	2.729e-122	393.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4EI6I@85012|Streptosporangiales	201174|Actinobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_1972567_5	1078020.KEK_20558	4.131e-91	309.0	COG0778@1|root,COG0778@2|Bacteria,2GM9M@201174|Actinobacteria,235BZ@1762|Mycobacteriaceae	201174|Actinobacteria	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_1972567_7	1229780.BN381_90031	6.13e-36	154.0	COG2845@1|root,COG2845@2|Bacteria,2GU62@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF459)	-	-	-	ko:K09795	-	-	-	-	ko00000	-	-	-	DUF459
BYD2_k127_1972567_4	326424.FRAAL6221	2.775e-95	347.0	COG1696@1|root,COG1696@2|Bacteria,2GM6Z@201174|Actinobacteria,4EUU2@85013|Frankiales	201174|Actinobacteria	M	MBOAT, membrane-bound O-acyltransferase family	algI	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
BYD2_k127_1972567_9	164757.Mjls_1687	7.389e-17	96.0	2DZHZ@1|root,31ZDG@2|Bacteria,2IN6I@201174|Actinobacteria,23A9W@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_1972567_1	926550.CLDAP_06320	5.384e-146	471.0	COG0667@1|root,COG0667@2|Bacteria,2G5YU@200795|Chloroflexi	200795|Chloroflexi	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
BYD2_k127_1972567_8	1313172.YM304_36130	8.015e-19	92.0	COG0716@1|root,COG0716@2|Bacteria	2|Bacteria	C	FMN binding	fldA	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
BYD2_k127_1972567_6	2002.JOEQ01000015_gene5119	1.566e-42	175.0	COG0715@1|root,COG0715@2|Bacteria,2GNBY@201174|Actinobacteria	201174|Actinobacteria	P	NMT1/THI5 like	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
BYD2_k127_1972567_0	1121272.KB903263_gene589	5.191e-165	533.0	COG3508@1|root,COG3508@2|Bacteria,2GKZV@201174|Actinobacteria,4DA7H@85008|Micromonosporales	201174|Actinobacteria	Q	homogentisate 12-dioxygenase	hmgA	-	1.13.11.5	ko:K00451	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R02519	RC00737	ko00000,ko00001,ko00002,ko01000	-	-	-	HgmA
BYD2_k127_1972567_2	1464048.JNZS01000002_gene480	6.427e-139	453.0	COG0179@1|root,COG0179@2|Bacteria,2GNGC@201174|Actinobacteria,4D8QR@85008|Micromonosporales	201174|Actinobacteria	Q	Fumarylacetoacetase	fahA	-	3.7.1.2	ko:K01555	ko00350,ko00643,ko01100,ko01120,map00350,map00643,map01100,map01120	M00044	R01364	RC00326,RC00446	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FAA_hydrolase,FAA_hydrolase_N
BYD2_k127_1972567_10	667632.KB890172_gene3999	4.869e-06	49.0	COG0277@1|root,COG0277@2|Bacteria,1MU6Y@1224|Proteobacteria,2VH5A@28216|Betaproteobacteria,1K0RZ@119060|Burkholderiaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcD2	-	1.1.2.4	ko:K00102	ko00620,map00620	-	R00197	RC00044	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_1985227_0	593907.Celgi_2593	2.891e-122	402.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type antimicrobial peptide transport system, permease component	yknZ	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_1985227_4	590998.Celf_0867	1.719e-46	193.0	COG0845@1|root,COG0845@2|Bacteria,2IG0C@201174|Actinobacteria	201174|Actinobacteria	M	HlyD family secretion protein	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3
BYD2_k127_1985227_2	2002.JOEQ01000004_gene2832	2.883e-89	304.0	COG5036@1|root,COG5036@2|Bacteria,2GKBU@201174|Actinobacteria,4EM33@85012|Streptosporangiales	201174|Actinobacteria	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
BYD2_k127_1985227_5	293826.Amet_0309	1.354e-34	146.0	COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes,24G1I@186801|Clostridia,36HHF@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
BYD2_k127_1985227_1	1137268.AZXF01000021_gene1459	1.226e-100	348.0	COG5337@1|root,COG5337@2|Bacteria,2GN9M@201174|Actinobacteria,4EMXN@85012|Streptosporangiales	201174|Actinobacteria	M	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
BYD2_k127_1985227_3	526225.Gobs_3634	4.443e-68	240.0	COG0300@1|root,COG0300@2|Bacteria,2IGCX@201174|Actinobacteria,4EVA1@85013|Frankiales	201174|Actinobacteria	S	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_2005327_3	402881.Plav_0577	1.339e-46	171.0	COG2175@1|root,COG2175@2|Bacteria,1Q0C7@1224|Proteobacteria,2TRGF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA	-	-	-	-	-	-	-	-	-	-	-	-	TauD
BYD2_k127_2005327_0	1125971.ASJB01000028_gene7782	6.113e-124	412.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DZWN@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_2005327_2	504728.K649_14710	1.898e-103	351.0	COG0446@1|root,COG0446@2|Bacteria	2|Bacteria	Q	pyridine nucleotide-disulphide oxidoreductase	sqr	GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114	1.8.5.4	ko:K17218	ko00920,map00920	-	R10152	RC03155	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
BYD2_k127_2005327_1	1146883.BLASA_3968	1.153e-117	395.0	COG0520@1|root,COG0520@2|Bacteria,2GMIC@201174|Actinobacteria,4EUQQ@85013|Frankiales	201174|Actinobacteria	E	Aminotransferase class-V	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
BYD2_k127_2005327_4	1123322.KB904635_gene2634	2.116e-13	70.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria	201174|Actinobacteria	E	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_2008110_46	1463881.KL591005_gene6191	3.219e-44	161.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	fadA6	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003988,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005758,GO:0005777,GO:0005782,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0031907,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0032787,GO:0034440,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:1901363,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_2008110_17	298655.KI912266_gene1939	3.219e-119	393.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ERP0@85013|Frankiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran,DUF4162
BYD2_k127_2008110_34	298655.KI912266_gene1940	5.305e-64	245.0	COG0842@1|root,COG0842@2|Bacteria,2IART@201174|Actinobacteria	201174|Actinobacteria	V	ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_3
BYD2_k127_2008110_37	1449353.JQMQ01000005_gene987	5.542e-59	231.0	COG0842@1|root,COG0842@2|Bacteria,2HNB6@201174|Actinobacteria,2NHZ8@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
BYD2_k127_2008110_51	1120950.KB892751_gene6780	2.366e-34	139.0	2ESVG@1|root,33KDV@2|Bacteria,2IA6T@201174|Actinobacteria,4DSPK@85009|Propionibacteriales	201174|Actinobacteria	S	CHRD domain	-	-	-	-	-	-	-	-	-	-	-	-	CHRD
BYD2_k127_2008110_1	479432.Sros_6703	5.447e-225	709.0	COG1960@1|root,COG1960@2|Bacteria,2GJHM@201174|Actinobacteria,4EFWE@85012|Streptosporangiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	aidB	-	-	ko:K09456	-	-	-	-	ko00000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
BYD2_k127_2008110_32	909613.UO65_6007	2.304e-66	239.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DXY0@85010|Pseudonocardiales	201174|Actinobacteria	J	PFAM SpoU rRNA Methylase family	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
BYD2_k127_2008110_19	1206744.BAGL01000055_gene1557	3.029e-112	375.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4G6G9@85025|Nocardiaceae	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_2008110_38	345341.KUTG_03449	1.685e-54	207.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E3H9@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
BYD2_k127_2008110_61	1005048.CFU_3298	1.574e-17	89.0	COG5580@1|root,COG5580@2|Bacteria,1NMBI@1224|Proteobacteria,2W5GZ@28216|Betaproteobacteria	28216|Betaproteobacteria	O	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_2008110_44	882083.SacmaDRAFT_2792	2.785e-46	176.0	COG0730@1|root,COG0730@2|Bacteria,2IIY7@201174|Actinobacteria,4E3NW@85010|Pseudonocardiales	201174|Actinobacteria	S	membrane transporter protein	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
BYD2_k127_2008110_23	1122611.KB903965_gene4970	6.181e-102	355.0	COG2141@1|root,COG2141@2|Bacteria,2GMMJ@201174|Actinobacteria,4EGKE@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2008110_15	1206741.BAFX01000008_gene6695	8.824e-123	428.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4FV5H@85025|Nocardiaceae	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_2008110_16	526225.Gobs_3681	9.534e-121	393.0	COG3386@1|root,COG3386@2|Bacteria,2HE8D@201174|Actinobacteria,4ETTP@85013|Frankiales	201174|Actinobacteria	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.15	ko:K13874,ko:K14274	ko00040,ko00053,ko01100,map00040,map00053,map01100	-	R02427,R02526	RC00537,RC00713	ko00000,ko00001,ko01000	-	-	-	SGL
BYD2_k127_2008110_31	1313172.YM304_37110	8.724e-72	250.0	COG0637@1|root,COG0637@2|Bacteria,2GJNG@201174|Actinobacteria	201174|Actinobacteria	E	IA, variant 3	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
BYD2_k127_2008110_3	1229780.BN381_90096	5.979e-184	582.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UX13@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Thiolase, C-terminal domain	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_2008110_21	525909.Afer_1991	9.959e-106	354.0	COG0491@1|root,COG0491@2|Bacteria,2I9GW@201174|Actinobacteria,4CNHS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
BYD2_k127_2008110_28	1313172.YM304_37370	4.284e-78	280.0	COG1570@1|root,COG1570@2|Bacteria,2GJAS@201174|Actinobacteria,4CNA1@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
BYD2_k127_2008110_65	1313172.YM304_37380	2.483e-07	64.0	COG1722@1|root,COG1722@2|Bacteria,2HD2Z@201174|Actinobacteria	201174|Actinobacteria	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	-	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
BYD2_k127_2008110_41	1121926.AXWO01000008_gene2990	2.841e-49	198.0	COG1309@1|root,COG1309@2|Bacteria,2IE9K@201174|Actinobacteria,4F01I@85014|Glycomycetales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2008110_22	1313172.YM304_37400	6.067e-103	347.0	COG0142@1|root,COG0142@2|Bacteria,2GJEK@201174|Actinobacteria,4CMXY@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Polyprenyl synthetase	-	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13787	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00365	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	polyprenyl_synt
BYD2_k127_2008110_39	1313172.YM304_38760	6.739e-54	209.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4,NAD_binding_4
BYD2_k127_2008110_13	1313172.YM304_38750	7.386e-125	415.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
BYD2_k127_2008110_64	1134912.AJTV01000062_gene3920	4.674e-11	74.0	COG5653@1|root,COG5653@2|Bacteria,1N3Z9@1224|Proteobacteria,2TRT5@28211|Alphaproteobacteria,36Y5Z@31993|Methylocystaceae	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
BYD2_k127_2008110_2	1214101.BN159_4428	6.177e-205	663.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria	201174|Actinobacteria	F	Drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_2008110_47	1077974.GOEFS_115_00900	6.418e-42	162.0	COG1309@1|root,COG1309@2|Bacteria,2GP91@201174|Actinobacteria,4GAVW@85026|Gordoniaceae	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
BYD2_k127_2008110_33	926550.CLDAP_17000	1.874e-65	235.0	COG1738@1|root,COG1738@2|Bacteria,2G6BZ@200795|Chloroflexi	200795|Chloroflexi	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
BYD2_k127_2008110_52	1122182.KB903825_gene888	2.059e-33	141.0	COG1073@1|root,COG1073@2|Bacteria,2I44C@201174|Actinobacteria,4DMJE@85008|Micromonosporales	201174|Actinobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_2008110_26	36809.MAB_3073	1.288e-82	294.0	COG2128@1|root,COG2128@2|Bacteria,2IAD2@201174|Actinobacteria,23864@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_2008110_6	2074.JNYD01000012_gene207	5.883e-159	512.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4DZJ7@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	cyp	-	1.14.15.14	ko:K20497	-	-	-	-	ko00000,ko00199,ko01000	-	-	-	p450
BYD2_k127_2008110_48	1448389.BAVQ01000002_gene2862	1.21e-38	154.0	COG3576@1|root,COG3576@2|Bacteria,2I3RW@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_2008110_27	1229780.BN381_410016	1.877e-79	285.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,3UWQF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
BYD2_k127_2008110_56	235985.BBPN01000020_gene6409	1.046e-30	131.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,2NHAY@228398|Streptacidiphilus	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_2008110_4	103733.JNYO01000012_gene2781	9.562e-171	552.0	COG1793@1|root,COG1793@2|Bacteria,2GJ2P@201174|Actinobacteria,4DXPV@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair	lig	GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K10747	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,DNA_ligase_A_N
BYD2_k127_2008110_40	1120950.KB892746_gene3466	7.752e-54	214.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria,4DVQA@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25,Methyltransf_31
BYD2_k127_2008110_18	1172181.KB911740_gene5276	2.647e-112	381.0	COG1167@1|root,COG1167@2|Bacteria,2GJ5P@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
BYD2_k127_2008110_45	1120972.AUMH01000002_gene2814	9.692e-45	168.0	COG2128@1|root,COG2128@2|Bacteria,1V97G@1239|Firmicutes,4HHFF@91061|Bacilli	91061|Bacilli	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	ydfG	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_2008110_24	298655.KI912266_gene5725	5.714e-97	325.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_2008110_53	67267.JNXT01000035_gene2336	6.257e-33	147.0	COG1309@1|root,COG1309@2|Bacteria,2IGNJ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_C_3,TetR_N
BYD2_k127_2008110_29	1229780.BN381_130066	2.135e-73	267.0	COG3662@1|root,COG3662@2|Bacteria,2GJD2@201174|Actinobacteria,3UWQV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2236)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2236
BYD2_k127_2008110_14	1265310.CCBD010000070_gene168	2.407e-123	401.0	COG1024@1|root,COG1024@2|Bacteria,2IC08@201174|Actinobacteria,236U9@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_2008110_36	58123.JOFJ01000002_gene2473	2.298e-59	225.0	COG0300@1|root,COG0596@1|root,COG0300@2|Bacteria,COG0596@2|Bacteria,2I2RM@201174|Actinobacteria,4EMXB@85012|Streptosporangiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,adh_short
BYD2_k127_2008110_42	2055.JNXA01000016_gene3273	2.402e-48	180.0	COG1309@1|root,COG1309@2|Bacteria,2GK1H@201174|Actinobacteria,4GCBE@85026|Gordoniaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2008110_49	743718.Isova_1236	7.592e-38	148.0	2CMJR@1|root,32U2B@2|Bacteria,2I804@201174|Actinobacteria,4F4MS@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2008110_54	1157637.KB892132_gene3661	1.357e-32	140.0	COG1309@1|root,COG1309@2|Bacteria,2IFMU@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
BYD2_k127_2008110_7	561175.KB894094_gene1900	6.431e-159	523.0	COG3670@1|root,COG3670@2|Bacteria,2GK7D@201174|Actinobacteria,4EGGD@85012|Streptosporangiales	201174|Actinobacteria	Q	Retinal pigment epithelial membrane protein	-	-	-	ko:K11159	-	-	-	-	ko00000	-	-	-	RPE65
BYD2_k127_2008110_59	675635.Psed_1075	8.088e-24	107.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria,4E048@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2008110_66	235985.BBPN01000019_gene6091	5.87e-07	61.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria,2NHIZ@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2008110_8	1313172.YM304_26920	2.494e-148	512.0	COG0210@1|root,COG0514@1|root,COG0210@2|Bacteria,COG0514@2|Bacteria,2GISS@201174|Actinobacteria,4CMS6@84992|Acidimicrobiia	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
BYD2_k127_2008110_55	1229780.BN381_630008	5.354e-32	142.0	COG3544@1|root,COG3544@2|Bacteria,2IKUE@201174|Actinobacteria,3UWSG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
BYD2_k127_2008110_43	247633.GP2143_07434	1.936e-46	179.0	COG1051@1|root,COG1051@2|Bacteria,1QUPQ@1224|Proteobacteria	1224|Proteobacteria	F	COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_2008110_63	1121946.AUAX01000029_gene1941	1.236e-16	86.0	2933D@1|root,2ZQKJ@2|Bacteria,2H0UQ@201174|Actinobacteria,4DK1Q@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2008110_10	448385.sce8911	6.154e-138	452.0	COG0520@1|root,COG0520@2|Bacteria,1MUPD@1224|Proteobacteria,42PJT@68525|delta/epsilon subdivisions,2WKPW@28221|Deltaproteobacteria,2YXCR@29|Myxococcales	28221|Deltaproteobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
BYD2_k127_2008110_50	1298864.AUEQ01000013_gene693	9.399e-36	147.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria,238T5@1762|Mycobacteriaceae	201174|Actinobacteria	S	CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
BYD2_k127_2008110_57	40571.JOEA01000009_gene3066	1.052e-30	132.0	COG5446@1|root,COG5446@2|Bacteria,2H6Y9@201174|Actinobacteria,4E3NJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Probable cobalt transporter subunit (CbtA)	-	-	-	-	-	-	-	-	-	-	-	-	CbtA
BYD2_k127_2008110_30	525909.Afer_0804	2.157e-73	251.0	COG2109@1|root,COG2109@2|Bacteria,2GNJQ@201174|Actinobacteria,4CN3K@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP	cobO	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
BYD2_k127_2008110_9	266117.Rxyl_0634	1.714e-139	460.0	COG1492@1|root,COG1492@2|Bacteria,2GJ1W@201174|Actinobacteria,4CPS0@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	-	CbiA,GATase_3
BYD2_k127_2008110_0	1137269.AZWL01000008_gene4630	0.0	1215.0	COG1429@1|root,COG1429@2|Bacteria,2GK0U@201174|Actinobacteria	201174|Actinobacteria	H	cobaltochelatase CobN subunit	cobN	-	6.6.1.2	ko:K02230	ko00860,ko01100,map00860,map01100	-	R05227	RC02000	ko00000,ko00001,ko01000	-	-	-	CobN-Mg_chel
BYD2_k127_2008110_11	1110697.NCAST_05_04530	1.312e-130	447.0	COG1239@1|root,COG1240@1|root,COG1239@2|Bacteria,COG1240@2|Bacteria,2GN3S@201174|Actinobacteria,4FVXW@85025|Nocardiaceae	201174|Actinobacteria	H	Magnesium chelatase, subunit ChlI	chlI	-	6.6.1.1	ko:K03404,ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	AAA_5,Mg_chelatase,VWA_2
BYD2_k127_2008110_5	526225.Gobs_2405	2.011e-163	551.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2ICMZ@201174|Actinobacteria,4EX4U@85013|Frankiales	201174|Actinobacteria	K	PFAM transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
BYD2_k127_2008110_25	1229780.BN381_240010	4.518e-95	324.0	COG3396@1|root,COG3396@2|Bacteria,2GMBI@201174|Actinobacteria,3UXKD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
BYD2_k127_2008110_20	1229780.BN381_130289	1.024e-110	366.0	COG1230@1|root,COG1230@2|Bacteria,2GMRZ@201174|Actinobacteria,3UWI0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Cation efflux family	czcD	-	-	ko:K16264	-	-	-	-	ko00000,ko02000	2.A.4.1	-	-	Cation_efflux
BYD2_k127_2008110_35	1122138.AQUZ01000073_gene4428	6.481e-62	219.0	COG1576@1|root,COG3631@1|root,COG1576@2|Bacteria,COG3631@2|Bacteria,2IGAN@201174|Actinobacteria,4DVE4@85009|Propionibacteriales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_2008110_12	1463864.JOGO01000018_gene1368	6.545e-126	429.0	COG1797@1|root,COG1797@2|Bacteria,2GJ3R@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source	cobB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2,CbiA,GATase_3
BYD2_k127_2008110_58	1380390.JIAT01000015_gene5786	2.992e-24	118.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,2GM8G@201174|Actinobacteria,4CPF4@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,PrmA,TP_methylase
BYD2_k127_2008110_60	68219.JNXI01000010_gene5796	6.13e-18	93.0	COG1276@1|root,COG2372@1|root,COG1276@2|Bacteria,COG2372@2|Bacteria,2GMKG@201174|Actinobacteria	201174|Actinobacteria	P	Copper resistance protein CopC	-	-	-	ko:K14166	-	-	-	-	ko00000,ko02000	-	-	-	CopC,CopD
BYD2_k127_2034450_4	204669.Acid345_3970	2.036e-21	100.0	2DQJB@1|root,3377V@2|Bacteria,3Y8JD@57723|Acidobacteria	57723|Acidobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2034450_1	479432.Sros_7870	6.683e-131	426.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4EHZF@85012|Streptosporangiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2034450_0	479435.Kfla_0728	2.08e-230	734.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4DU3U@85009|Propionibacteriales	201174|Actinobacteria	G	Alpha-amylase domain	-	-	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
BYD2_k127_2034450_2	1380390.JIAT01000013_gene199	1.665e-91	331.0	COG1879@1|root,COG1879@2|Bacteria,2HFUA@201174|Actinobacteria,4CTI2@84995|Rubrobacteria	84995|Rubrobacteria	G	Periplasmic binding proteins and sugar binding domain of LacI family	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
BYD2_k127_2034450_3	1380390.JIAT01000013_gene200	2.354e-54	194.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4CQ95@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
BYD2_k127_2041642_1	33876.JNXY01000009_gene8886	9.098e-10	70.0	COG0642@1|root,COG2205@2|Bacteria,2I2WT@201174|Actinobacteria,4DBZG@85008|Micromonosporales	201174|Actinobacteria	T	Nitrate and nitrite sensing	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_2041642_0	298655.KI912267_gene6984	2.732e-170	558.0	COG2234@1|root,COG2234@2|Bacteria,2GJ67@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
BYD2_k127_2041642_2	745411.B3C1_06268	1.947e-07	63.0	COG5083@1|root,COG5083@2|Bacteria,1R6Q7@1224|Proteobacteria,1S13P@1236|Gammaproteobacteria,1JA0J@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	LNS2	-	-	-	-	-	-	-	-	-	-	-	-	LNS2
BYD2_k127_2054928_0	1229780.BN381_310054	7.552e-249	787.0	COG1138@1|root,COG1138@2|Bacteria,2HZM9@201174|Actinobacteria	201174|Actinobacteria	O	Cytochrome c-type biogenesis protein CcmF	ccmF	-	-	ko:K02198	-	-	-	-	ko00000,ko02000	9.B.14.1	-	-	CcmF_C,Cytochrom_C_asm
BYD2_k127_2054928_4	1229780.BN381_310055	2.439e-44	169.0	COG0526@1|root,COG0526@2|Bacteria	2|Bacteria	CO	cell redox homeostasis	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA
BYD2_k127_2054928_8	690597.JH730938_gene2123	2.155e-09	69.0	COG3088@1|root,COG3088@2|Bacteria,1MZZ5@1224|Proteobacteria,1S9DV@1236|Gammaproteobacteria,1YQ65@136843|Pseudomonas fluorescens group	1236|Gammaproteobacteria	P	subunit of a heme lyase	ccmH	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567	-	ko:K02200	-	-	-	-	ko00000	-	-	-	CcmH
BYD2_k127_2054928_7	1313172.YM304_09680	8.983e-26	113.0	COG2062@1|root,COG2062@2|Bacteria	2|Bacteria	T	phosphohistidine phosphatase, SixA	sixA	-	3.6.1.55	ko:K03574,ko:K08296	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	His_Phos_1,NUDIX
BYD2_k127_2054928_2	1229780.BN381_310060	6.343e-122	402.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,3UWEF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
BYD2_k127_2054928_5	1121877.JQKF01000016_gene162	7.16e-40	166.0	COG2345@1|root,COG2345@2|Bacteria,2HGTI@201174|Actinobacteria,4CNV8@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_2054928_1	1229780.BN381_310061	7.059e-186	590.0	COG0489@1|root,COG0489@2|Bacteria,2GJUZ@201174|Actinobacteria,3UWC1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	GO:0008150,GO:0040007	-	ko:K03593	-	-	-	-	ko00000,ko03029,ko03036	-	-	-	FeS_assembly_P,ParA
BYD2_k127_2054928_3	1313172.YM304_16870	8.401e-58	203.0	COG2267@1|root,COG2267@2|Bacteria,2GJNF@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
BYD2_k127_2067338_3	512565.AMIS_19440	5.177e-35	135.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4DM4B@85008|Micromonosporales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_2067338_1	101510.RHA1_ro04667	1.148e-132	435.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4FZ1Q@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the cytochrome P450 family	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
BYD2_k127_2067338_2	1229780.BN381_130223	1.874e-65	235.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
BYD2_k127_2067338_0	402881.Plav_2680	9.104e-209	665.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
BYD2_k127_2067338_4	134676.ACPL_1841	3.455e-22	108.0	COG0740@1|root,COG0740@2|Bacteria,2GPTS@201174|Actinobacteria,4DF0Y@85008|Micromonosporales	201174|Actinobacteria	OU	Belongs to the peptidase S14 family	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
BYD2_k127_2067338_5	1121022.ABENE_19365	5.411e-05	55.0	COG4299@1|root,COG4299@2|Bacteria,1R5FB@1224|Proteobacteria	1224|Proteobacteria	S	COGs COG4299 conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF1624,DUF5009
BYD2_k127_209627_3	1229780.BN381_90075	1.233e-34	138.0	COG5496@1|root,COG5496@2|Bacteria,2IKZP@201174|Actinobacteria,3UXP7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_209627_0	1229780.BN381_90073	6.05e-221	694.0	COG0312@1|root,COG0312@2|Bacteria,2GJ4E@201174|Actinobacteria,3UXHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative modulator of DNA gyrase	-	-	-	ko:K03568	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
BYD2_k127_209627_1	1313172.YM304_10900	3.78e-131	433.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
BYD2_k127_209627_2	1313172.YM304_10900	7.221e-87	309.0	COG0312@1|root,COG0312@2|Bacteria,2HGNU@201174|Actinobacteria,4CNQT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative modulator of DNA gyrase	-	-	-	ko:K03592	-	-	-	-	ko00000,ko01002	-	-	-	PmbA_TldD
BYD2_k127_2101195_1	1380354.JIAN01000007_gene369	1.362e-33	132.0	COG1396@1|root,COG1396@2|Bacteria,2GKRR@201174|Actinobacteria,4F2VJ@85016|Cellulomonadaceae	201174|Actinobacteria	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
BYD2_k127_2101195_0	1463825.JNXC01000027_gene3223	4.028e-115	374.0	COG0262@1|root,COG0262@2|Bacteria,2H16K@201174|Actinobacteria,4EEN8@85010|Pseudonocardiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_2101195_2	298655.KI912266_gene4081	5.995e-25	109.0	COG3631@1|root,COG3631@2|Bacteria,2IM0Y@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_2107327_0	1229780.BN381_40064	9.144e-125	416.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
BYD2_k127_2107327_1	1476876.JOJO01000013_gene4699	2.284e-57	203.0	COG0346@1|root,COG0346@2|Bacteria,2IKTR@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_2107327_2	590998.Celf_0778	5.525e-28	127.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_211214_5	1283283.ATXA01000021_gene2882	2.504e-40	154.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ES16@85013|Frankiales	201174|Actinobacteria	V	TIGRFAM daunorubicin resistance ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_211214_3	981369.JQMJ01000004_gene522	1.521e-91	309.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,2NHE9@228398|Streptacidiphilus	201174|Actinobacteria	V	ABC-2 family transporter protein	-	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
BYD2_k127_211214_4	1122609.AUGT01000001_gene2836	1.573e-90	314.0	COG3173@1|root,COG3173@2|Bacteria,2IA48@201174|Actinobacteria,4DR9I@85009|Propionibacteriales	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_211214_6	1032480.MLP_35470	8.259e-28	130.0	COG0500@1|root,COG2226@2|Bacteria,2GUHW@201174|Actinobacteria,4DS9J@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_211214_1	1313172.YM304_22760	8.948e-123	404.0	COG0861@1|root,COG0861@2|Bacteria,2GIWU@201174|Actinobacteria	201174|Actinobacteria	P	membrane protein terC	-	-	-	ko:K05794	-	-	-	-	ko00000	-	-	-	TerC
BYD2_k127_211214_0	1313172.YM304_22750	0.0	1246.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GK73@201174|Actinobacteria,4CMX0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Belongs to the PEP-utilizing enzyme family	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
BYD2_k127_211214_2	1122138.AQUZ01000019_gene8186	7.621e-120	400.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
BYD2_k127_2133592_1	1229780.BN381_130104	4.247e-32	128.0	COG1077@1|root,COG1077@2|Bacteria	2|Bacteria	D	Cell shape determining protein MreB Mrl	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
BYD2_k127_2133592_0	469383.Cwoe_0422	4.597e-114	382.0	COG0502@1|root,COG0502@2|Bacteria,2GIUE@201174|Actinobacteria,4CR7S@84995|Rubrobacteria	201174|Actinobacteria	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1589	BATS,Radical_SAM
BYD2_k127_2133592_2	1229780.BN381_250066	3.544e-30	123.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_2136497_3	710111.FraQA3DRAFT_3807	2.459e-07	63.0	COG3266@1|root,COG4251@1|root,COG3266@2|Bacteria,COG4251@2|Bacteria,2GK6E@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	cvnA6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_2136497_0	134676.ACPL_2138	2.542e-72	249.0	COG2229@1|root,COG2229@2|Bacteria,2HV3I@201174|Actinobacteria,4D923@85008|Micromonosporales	201174|Actinobacteria	S	Conserved hypothetical ATP binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
BYD2_k127_2136497_2	1449976.KALB_1772	1.346e-10	71.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	2.7.1.83	ko:K16328	ko00240,map00240	-	R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF3489,DUF742
BYD2_k127_2136497_1	1160137.KB907307_gene3814	1.588e-39	153.0	COG2018@1|root,COG2018@2|Bacteria,2IFP1@201174|Actinobacteria,4G0P4@85025|Nocardiaceae	201174|Actinobacteria	S	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
BYD2_k127_2188319_3	1380386.JIAW01000003_gene826	2.354e-99	344.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria,234NC@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_2188319_4	745776.DGo_CA1525	4.234e-73	262.0	COG2301@1|root,COG2301@2|Bacteria	2|Bacteria	G	Belongs to the HpcH HpaI aldolase family	citE	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0046872,GO:0071704	4.1.3.25,4.1.3.34	ko:K01644,ko:K18292	ko00660,ko01100,ko02020,map00660,map01100,map02020	-	R00237,R00362	RC00067,RC00502,RC01118,RC01205	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
BYD2_k127_2188319_5	1540221.JQNI01000002_gene1027	5.321e-54	201.0	COG2030@1|root,COG2030@2|Bacteria,1WJC4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
BYD2_k127_2188319_1	1156844.KB891797_gene5596	4.385e-171	563.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	fadD16	-	6.2.1.41	ko:K18687	ko00984,ko01100,ko01120,map00984,map01100,map01120	-	R10769	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_2188319_6	298653.Franean1_3688	2.324e-17	95.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria,4ETXR@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_2188319_2	285535.JOEY01000006_gene8159	4.906e-144	465.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2188319_0	365528.KB891262_gene5089	2.914e-182	579.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_2191318_1	1313172.YM304_18500	1.468e-28	115.0	COG0227@1|root,COG0227@2|Bacteria,2HH3N@201174|Actinobacteria,4CP3S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
BYD2_k127_2191318_2	1313172.YM304_18490	1.709e-24	107.0	COG1278@1|root,COG1278@2|Bacteria,2HC2C@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	-
BYD2_k127_2191318_0	1229780.BN381_10340	1.511e-223	704.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,3UWAV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0016020,GO:0019725,GO:0030003,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0071944,GO:0075136,GO:0098771	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
BYD2_k127_2204454_18	68170.KL590552_gene8222	8.732e-35	136.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4DYX8@85010|Pseudonocardiales	201174|Actinobacteria	CG	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
BYD2_k127_2204454_22	675635.Psed_4350	7.212e-13	81.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_2204454_4	1157640.AQWO01000004_gene4809	6.887e-124	429.0	COG2227@1|root,COG2227@2|Bacteria,2GNRH@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
BYD2_k127_2204454_16	106370.Francci3_0716	9.382e-43	163.0	COG1309@1|root,COG1309@2|Bacteria,2HG87@201174|Actinobacteria,4EVUR@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2204454_1	469383.Cwoe_3291	5.093e-172	558.0	COG0477@1|root,COG1846@1|root,COG0477@2|Bacteria,COG1846@2|Bacteria,2GJ09@201174|Actinobacteria,4CP7Q@84995|Rubrobacteria	84995|Rubrobacteria	EGP	Fungal trichothecene efflux pump (TRI12)	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_2204454_3	471852.Tcur_0579	2.386e-126	423.0	COG5002@1|root,COG5002@2|Bacteria,2I2DU@201174|Actinobacteria,4EHHW@85012|Streptosporangiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_2204454_7	1120936.KB907215_gene4161	2.166e-100	335.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4EI79@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	phoP	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_2204454_10	1120950.KB892768_gene5344	1.364e-84	304.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,4DNEM@85009|Propionibacteriales	201174|Actinobacteria	O	Trypsin-like peptidase domain	pepD	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
BYD2_k127_2204454_9	1068980.ARVW01000001_gene6015	5.311e-90	302.0	COG0406@1|root,COG0406@2|Bacteria,2HUBQ@201174|Actinobacteria,4E141@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
BYD2_k127_2204454_2	35754.JNYJ01000031_gene6977	1.728e-132	453.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DAB5@85008|Micromonosporales	201174|Actinobacteria	T	signal transduction protein containing a membrane domain, an EAL and a GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
BYD2_k127_2204454_5	1121272.KB903249_gene1789	4.809e-120	391.0	COG1878@1|root,COG1878@2|Bacteria,2GNFV@201174|Actinobacteria,4DCEI@85008|Micromonosporales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
BYD2_k127_2204454_15	405948.SACE_0740	1.824e-48	186.0	COG3981@1|root,COG3981@2|Bacteria,2IGK9@201174|Actinobacteria,4E4TP@85010|Pseudonocardiales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
BYD2_k127_2204454_20	1869.MB27_10045	3.529e-30	134.0	COG0346@1|root,COG0346@2|Bacteria,2IQJB@201174|Actinobacteria,4DJXM@85008|Micromonosporales	201174|Actinobacteria	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2204454_11	1313172.YM304_33960	2.638e-83	289.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,2IQM9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
BYD2_k127_2204454_13	1146883.BLASA_2841	6.168e-67	241.0	COG1752@1|root,COG1752@2|Bacteria,2IB0F@201174|Actinobacteria,4ET56@85013|Frankiales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_2204454_17	882086.SacxiDRAFT_4363	3.626e-35	138.0	COG0346@1|root,COG0346@2|Bacteria,2II0X@201174|Actinobacteria,4E523@85010|Pseudonocardiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_2204454_12	1068980.ARVW01000001_gene7940	3.585e-79	278.0	COG1018@1|root,COG1018@2|Bacteria,2GJSW@201174|Actinobacteria,4E315@85010|Pseudonocardiales	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
BYD2_k127_2204454_6	1265310.CCBD010000069_gene459	6.093e-108	378.0	COG3239@1|root,COG3239@2|Bacteria,2GJKF@201174|Actinobacteria,232R3@1762|Mycobacteriaceae	201174|Actinobacteria	I	fatty acid desaturase	desA3_2	-	1.14.19.3	ko:K00508	ko00591,ko01100,map00591,map01100	-	R07063	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase
BYD2_k127_2204454_8	675635.Psed_3642	1.673e-96	327.0	COG2227@1|root,COG2227@2|Bacteria,2I3SM@201174|Actinobacteria,4EF8V@85010|Pseudonocardiales	201174|Actinobacteria	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
BYD2_k127_2204454_23	1286093.C266_23156	8.723e-12	79.0	COG4454@1|root,COG4454@2|Bacteria,1R91G@1224|Proteobacteria,2VSS8@28216|Betaproteobacteria,1K8EJ@119060|Burkholderiaceae	28216|Betaproteobacteria	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind
BYD2_k127_2204454_0	390989.JOEG01000005_gene2042	2.012e-282	885.0	COG0365@1|root,COG0365@2|Bacteria,2GM20@201174|Actinobacteria,4D8NB@85008|Micromonosporales	201174|Actinobacteria	I	Acetyl-coenzyme A synthetase N-terminus	-	-	6.2.1.16	ko:K01907	ko00280,ko00650,map00280,map00650	-	R01357	RC00004,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
BYD2_k127_2217518_0	1906.SFRA_07890	3.788e-84	297.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase M50B family	-	-	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
BYD2_k127_2217518_1	1380355.JNIJ01000007_gene3289	2.733e-25	112.0	COG0640@1|root,COG0640@2|Bacteria,1RCIH@1224|Proteobacteria,2U6EZ@28211|Alphaproteobacteria,3K3ZG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_2217518_3	446471.Xcel_0874	1.203e-08	66.0	2CIBE@1|root,32S7P@2|Bacteria,2IRU5@201174|Actinobacteria,4F4VH@85017|Promicromonosporaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2217518_2	1122951.ATUE01000005_gene2003	1.051e-13	76.0	COG1872@1|root,COG1872@2|Bacteria,1MZ4E@1224|Proteobacteria,1S9AB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the UPF0235 family	yggU	-	-	ko:K09131	-	-	-	-	ko00000	-	-	-	DUF167
BYD2_k127_2240487_3	525909.Afer_0762	4.575e-62	235.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
BYD2_k127_2240487_0	1313172.YM304_18300	3.803e-95	331.0	COG0544@1|root,COG0544@2|Bacteria,2GJIG@201174|Actinobacteria,4CN55@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	Trigger_C,Trigger_N
BYD2_k127_2240487_4	1183438.GKIL_2486	2.205e-12	81.0	298HN@1|root,2ZVNP@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2240487_2	196162.Noca_3341	1.059e-67	235.0	COG1832@1|root,COG1832@2|Bacteria,2IJYY@201174|Actinobacteria	201174|Actinobacteria	S	PFAM CoA-binding domain protein	-	-	-	ko:K06929	-	-	-	-	ko00000	-	-	-	CoA_binding_2
BYD2_k127_2240487_1	471852.Tcur_4538	1.845e-93	314.0	COG2343@1|root,COG2343@2|Bacteria,2IKUM@201174|Actinobacteria,4EJGR@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF427)	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_9
BYD2_k127_2273408_5	479432.Sros_9038	1.774e-09	59.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4EMB0@85012|Streptosporangiales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
BYD2_k127_2273408_2	298654.FraEuI1c_1116	2.192e-44	176.0	COG1595@1|root,COG1595@2|Bacteria,2IKVM@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_2273408_4	68219.JNXI01000020_gene8075	1.244e-14	83.0	COG0500@1|root,COG2226@2|Bacteria,2GP9N@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_2273408_0	1313172.YM304_18530	3.249e-278	874.0	COG1200@1|root,COG1200@2|Bacteria,2GKA3@201174|Actinobacteria,4CMPC@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
BYD2_k127_2273408_1	1313172.YM304_18510	7.819e-172	557.0	COG1461@1|root,COG1461@2|Bacteria,2GKII@201174|Actinobacteria,4CMTA@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Dak1_2	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
BYD2_k127_2273408_3	1313172.YM304_18500	3.737e-28	114.0	COG0227@1|root,COG0227@2|Bacteria,2HH3N@201174|Actinobacteria,4CP3S@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal L28 family	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
BYD2_k127_2273424_1	1229780.BN381_150009	6.781e-131	441.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,3UWGP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_2273424_0	1229780.BN381_150010	5.869e-146	471.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,3UW6J@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
BYD2_k127_2273424_5	247156.NFA_27990	8.711e-34	136.0	2DNTJ@1|root,32Z2U@2|Bacteria,2I8BW@201174|Actinobacteria,4GA2K@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
BYD2_k127_2273424_4	1464048.JNZS01000010_gene5117	5.76e-53	189.0	COG0346@1|root,COG0346@2|Bacteria,2IIMV@201174|Actinobacteria,4DEC9@85008|Micromonosporales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,TetR_N
BYD2_k127_2273424_2	525909.Afer_1577	2.257e-124	431.0	COG0642@1|root,COG1129@1|root,COG1129@2|Bacteria,COG2205@2|Bacteria,2GJDV@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter	-	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
BYD2_k127_2273424_3	525909.Afer_1576	3.078e-80	278.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_2273424_6	1123065.ATWL01000005_gene1386	6.93e-28	120.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria	201174|Actinobacteria	G	ABC transporter substrate-binding protein	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
BYD2_k127_2287490_7	645465.ACUR01000501_gene2491	3.113e-65	231.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
BYD2_k127_2287490_12	467200.ACFA01000687_gene2080	1.033e-07	61.0	COG3023@1|root,COG3409@1|root,COG3023@2|Bacteria,COG3409@2|Bacteria,2GJ9M@201174|Actinobacteria	201174|Actinobacteria	V	Negative regulator of	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,PG_binding_1
BYD2_k127_2287490_0	1150864.MILUP08_46168	1.044e-233	728.0	COG0538@1|root,COG0538@2|Bacteria,2GM3D@201174|Actinobacteria,4D97E@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
BYD2_k127_2287490_10	1127134.NOCYR_4774	3.293e-27	120.0	2CK3K@1|root,32SBH@2|Bacteria,2IQJH@201174|Actinobacteria,4G23H@85025|Nocardiaceae	201174|Actinobacteria	S	Ion channel	-	-	-	-	-	-	-	-	-	-	-	-	Ion_trans_2
BYD2_k127_2287490_13	326298.Suden_0122	0.0001809	53.0	2BUAB@1|root,32PJW@2|Bacteria,1Q49J@1224|Proteobacteria,42YP0@68525|delta/epsilon subdivisions,2YR52@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2287490_4	1229780.BN381_640016	1.745e-145	475.0	COG0863@1|root,COG0863@2|Bacteria	2|Bacteria	L	N-4 methylation of cytosine	bglIM	-	2.1.1.113,2.1.1.72	ko:K00571,ko:K00590	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	N6_N4_Mtase
BYD2_k127_2287490_6	1229780.BN381_130064	5.505e-103	342.0	COG0685@1|root,COG0685@2|Bacteria,2GJTN@201174|Actinobacteria,3UWKR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Methylenetetrahydrofolate reductase	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
BYD2_k127_2287490_5	338963.Pcar_2461	1.316e-117	391.0	COG0190@1|root,COG0190@2|Bacteria,1MWU4@1224|Proteobacteria,42MW0@68525|delta/epsilon subdivisions,2WJ90@28221|Deltaproteobacteria,43UKB@69541|Desulfuromonadales	28221|Deltaproteobacteria	F	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
BYD2_k127_2287490_8	1111729.ATYV01000001_gene2332	8.304e-65	233.0	COG0024@1|root,COG0024@2|Bacteria,2GKIZ@201174|Actinobacteria,22JZ9@1653|Corynebacteriaceae	2|Bacteria	E	Methionine aminopeptidase	map2	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
BYD2_k127_2287490_1	1313172.YM304_07240	6.261e-168	552.0	COG0138@1|root,COG0138@2|Bacteria,2GJWU@201174|Actinobacteria,4CMQ0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	AICARFT/IMPCHase bienzyme	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas,MGS
BYD2_k127_2287490_9	1229780.BN381_130059	6.168e-52	195.0	COG0299@1|root,COG0299@2|Bacteria,2H8QB@201174|Actinobacteria,3UWRP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	GO:0000287,GO:0003674,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0034641,GO:0042558,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0046653,GO:0046872,GO:0051186,GO:0071704,GO:1901360,GO:1901564	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	-	Formyl_trans_N
BYD2_k127_2287490_3	1229780.BN381_130058	3.847e-153	490.0	COG0074@1|root,COG0074@2|Bacteria,2GK00@201174|Actinobacteria,3UWCZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit	sucD	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	6.2.1.5	ko:K01902	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding,Ligase_CoA
BYD2_k127_2287490_2	1313172.YM304_36100	1.073e-153	494.0	COG0045@1|root,COG0045@2|Bacteria,2GKSB@201174|Actinobacteria,4CMVM@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit	sucC	-	6.2.1.5	ko:K01903	ko00020,ko00640,ko00660,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00640,map00660,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00405,R02404	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_2,Ligase_CoA
BYD2_k127_2287637_0	40571.JOEA01000045_gene5569	4.449e-155	503.0	COG0477@1|root,COG0477@2|Bacteria,2GMFC@201174|Actinobacteria,4DZE8@85010|Pseudonocardiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_2287637_1	710111.FraQA3DRAFT_4604	1.852e-70	251.0	2BXSN@1|root,32R1X@2|Bacteria,2GN1N@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4243)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4243
BYD2_k127_2289473_2	929712.KI912613_gene1912	1.036e-49	193.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4CQYN@84995|Rubrobacteria	84995|Rubrobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_2289473_3	1054860.KB913030_gene52	2.046e-10	74.0	2EREK@1|root,33J04@2|Bacteria,2IRRD@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2289473_0	369723.Strop_1560	2.916e-174	565.0	COG2723@1|root,COG2723@2|Bacteria,2GJAF@201174|Actinobacteria,4DAN2@85008|Micromonosporales	201174|Actinobacteria	G	Beta-glucosidase	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
BYD2_k127_2289473_1	570268.ANBB01000054_gene4616	1.544e-93	338.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4EHJN@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn _helix lactose operon repressor	cebR	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
BYD2_k127_2292212_24	710686.Mycsm_06053	2.751e-55	216.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23CU1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
BYD2_k127_2292212_7	44454.NF84_20395	4.202e-127	415.0	COG0111@1|root,COG0111@2|Bacteria,2GIZV@201174|Actinobacteria,236W4@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	serA2	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
BYD2_k127_2292212_21	47839.CCAU010000004_gene1020	2.432e-66	233.0	COG0235@1|root,COG0235@2|Bacteria,2GNI6@201174|Actinobacteria,235JB@1762|Mycobacteriaceae	201174|Actinobacteria	G	Aldolase	fucA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008742,GO:0009056,GO:0009058,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019324,GO:0019566,GO:0019568,GO:0019569,GO:0019572,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046373,GO:0046872,GO:0046914,GO:0051167,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901159,GO:1901575,GO:1901576	4.1.1.104,4.1.2.17,5.1.3.4	ko:K01628,ko:K03077,ko:K22130	ko00040,ko00051,ko00053,ko01100,ko01120,map00040,map00051,map00053,map01100,map01120	M00550	R02262,R05850	RC00603,RC00604,RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
BYD2_k127_2292212_10	1041522.MCOL_V216609	4.178e-124	426.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,2363K@1762|Mycobacteriaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
BYD2_k127_2292212_17	298653.Franean1_4041	5.566e-80	290.0	COG0410@1|root,COG0410@2|Bacteria	2|Bacteria	E	branched-chain amino acid transmembrane transporter activity	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_2292212_13	298653.Franean1_4040	1.245e-93	347.0	COG0411@1|root,COG0411@2|Bacteria,2ICYZ@201174|Actinobacteria	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_2292212_0	298653.Franean1_4038	6.121e-278	870.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
BYD2_k127_2292212_6	222534.KB893719_gene1026	8.142e-134	441.0	COG0683@1|root,COG0683@2|Bacteria	2|Bacteria	E	ABC-type branched-chain amino acid transport systems, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
BYD2_k127_2292212_32	1408452.JAGZ01000001_gene3404	1.841e-17	83.0	COG1141@1|root,COG1141@2|Bacteria,2GSUD@201174|Actinobacteria,23BGM@1762|Mycobacteriaceae	201174|Actinobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	-	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
BYD2_k127_2292212_9	1169154.KB897779_gene2871	1.988e-124	425.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria	201174|Actinobacteria	L	DNA helicase	helD	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2
BYD2_k127_2292212_4	1229780.BN381_250088	9.171e-168	543.0	COG1020@1|root,COG1020@2|Bacteria,2GKGU@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the long-chain O-acyltransferase family	-	GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
BYD2_k127_2292212_30	298655.KI912266_gene5563	3.241e-23	112.0	2FIRN@1|root,34AHB@2|Bacteria,2IHJ0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2292212_16	1229780.BN381_10037	8.892e-87	307.0	COG0410@1|root,COG0410@2|Bacteria,2I8GT@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_2292212_18	1123320.KB889697_gene8873	3.188e-74	281.0	COG0411@1|root,COG0411@2|Bacteria,2H5WA@201174|Actinobacteria	201174|Actinobacteria	E	PFAM ABC transporter related	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_2292212_3	1229780.BN381_130215	4.18e-172	584.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_2292212_14	1229780.BN381_130214	8.424e-92	319.0	COG0683@1|root,COG0683@2|Bacteria,2IE69@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
BYD2_k127_2292212_26	1283299.AUKG01000003_gene289	4.438e-54	193.0	COG1959@1|root,COG1959@2|Bacteria,2INF3@201174|Actinobacteria,4CQ7H@84995|Rubrobacteria	84995|Rubrobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
BYD2_k127_2292212_15	1068978.AMETH_3171	1.482e-90	304.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria,4EA88@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.149,4.2.1.17	ko:K01692,ko:K08299	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093,R10675	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_2292212_33	526225.Gobs_4263	7.863e-15	85.0	COG1051@1|root,COG1051@2|Bacteria,2IQEU@201174|Actinobacteria,4ETAP@85013|Frankiales	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_2292212_31	1229780.BN381_400023	8.544e-23	110.0	COG0454@1|root,COG0456@2|Bacteria,2HBQK@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_2292212_35	1121877.JQKF01000002_gene1631	6.502e-12	72.0	2DDS5@1|root,2ZJ1Y@2|Bacteria,2HDMP@201174|Actinobacteria,4CP3T@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2292212_2	1313172.YM304_25950	1.816e-231	732.0	COG1351@1|root,COG1351@2|Bacteria,2HBYZ@201174|Actinobacteria,4CMUK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
BYD2_k127_2292212_8	1229780.BN381_400028	1.343e-126	432.0	COG1473@1|root,COG1473@2|Bacteria,2GNEG@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase, M20	amiB1	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
BYD2_k127_2292212_25	604331.AUHY01000081_gene209	1.344e-54	213.0	COG0604@1|root,COG0604@2|Bacteria,1WI1Y@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	COG0604 NADPH quinone reductase and related Zn-dependent	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_2292212_28	1313172.YM304_25960	9.287e-32	135.0	COG1597@1|root,COG1597@2|Bacteria,2HCNI@201174|Actinobacteria	201174|Actinobacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2292212_1	1229780.BN381_400030	4.98e-266	846.0	COG4581@1|root,COG4581@2|Bacteria,2GJEX@201174|Actinobacteria,3UWB3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DSHCT	helY	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K03727	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,DSHCT,Helicase_C,rRNA_proc-arch
BYD2_k127_2292212_20	1313172.YM304_25980	4.267e-68	240.0	COG0805@1|root,COG0805@2|Bacteria,2GJK8@201174|Actinobacteria,4CN3F@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides	tatC	-	-	ko:K03118	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	TatC
BYD2_k127_2292212_36	883.DvMF_3124	2.033e-09	66.0	COG1826@1|root,COG1826@2|Bacteria,1NI3F@1224|Proteobacteria,42VIZ@68525|delta/epsilon subdivisions,2WRC5@28221|Deltaproteobacteria,2MDCV@213115|Desulfovibrionales	28221|Deltaproteobacteria	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes	tatB	-	-	ko:K03116,ko:K03117	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
BYD2_k127_2292212_19	1313172.YM304_26000	5.998e-72	250.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
BYD2_k127_2292212_27	1229780.BN381_400037	7.301e-39	158.0	COG0681@1|root,COG0681@2|Bacteria,2GIYN@201174|Actinobacteria,3UWRN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Belongs to the peptidase S26 family	lepB	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24,Peptidase_S26
BYD2_k127_2292212_22	1229780.BN381_400038	5.74e-66	253.0	COG2378@1|root,COG2378@2|Bacteria,2GMAU@201174|Actinobacteria,3UWZY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	WYL domain	pafC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
BYD2_k127_2292212_23	1229780.BN381_400039	1.947e-62	238.0	COG2378@1|root,COG2378@2|Bacteria,2GM46@201174|Actinobacteria,3UWZ5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	WYL domain	pafB	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K13572,ko:K13573	-	-	-	-	ko00000,ko03051	-	-	-	WYL
BYD2_k127_2292212_11	1229780.BN381_400040	5.287e-104	348.0	COG3502@1|root,COG3502@2|Bacteria,2H2JJ@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3866)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3866
BYD2_k127_2292212_5	1313172.YM304_26020	9.994e-150	477.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
BYD2_k127_2292291_9	1229780.BN381_130039	1.836e-30	122.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,3UW7Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
BYD2_k127_2292291_1	1906.SFRA_02215	4.427e-128	428.0	COG0042@1|root,COG0042@2|Bacteria,2GJ8I@201174|Actinobacteria	201174|Actinobacteria	J	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	-	-	-	-	-	-	-	-	-	Dus
BYD2_k127_2292291_4	1169161.KB897717_gene2957	9.362e-65	230.0	COG0424@1|root,COG0424@2|Bacteria,2GNI0@201174|Actinobacteria	201174|Actinobacteria	D	Maf-like protein	maf	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf,NUDIX
BYD2_k127_2292291_8	1229780.BN381_130040	1.484e-39	159.0	COG0494@1|root,COG0494@2|Bacteria,2GKG9@201174|Actinobacteria,3UWZK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_2292291_0	309801.trd_1438	2.05e-216	682.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,2G5ZX@200795|Chloroflexi,27XW4@189775|Thermomicrobia	189775|Thermomicrobia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
BYD2_k127_2292291_10	1380393.JHVP01000007_gene4325	3.359e-20	106.0	2EPJR@1|root,33H6B@2|Bacteria,2GXK1@201174|Actinobacteria,4EWWU@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2292291_2	1394178.AWOO02000100_gene8282	4.368e-116	399.0	COG2041@1|root,COG2041@2|Bacteria,2GIZH@201174|Actinobacteria,4ENAJ@85012|Streptosporangiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
BYD2_k127_2292291_7	1449976.KALB_733	1.141e-40	169.0	COG0500@1|root,COG0500@2|Bacteria,2I2R3@201174|Actinobacteria,4E3W2@85010|Pseudonocardiales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
BYD2_k127_2292291_5	66429.JOFL01000006_gene1996	4.25e-60	215.0	COG3222@1|root,COG3222@2|Bacteria,2GN3B@201174|Actinobacteria	201174|Actinobacteria	Q	protein conserved in bacteria	-	-	-	ko:K09931	-	-	-	-	ko00000	-	-	-	DUF2064
BYD2_k127_2292291_3	1394178.AWOO02000011_gene4017	3.008e-93	312.0	COG0745@1|root,COG0745@2|Bacteria,2GK5S@201174|Actinobacteria,4EHHP@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_2292291_6	1464048.JNZS01000007_gene4520	1.32e-49	199.0	COG0642@1|root,COG2205@2|Bacteria,2I3JI@201174|Actinobacteria,4DMR4@85008|Micromonosporales	201174|Actinobacteria	T	PFAM ATP-binding region, ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BYD2_k127_2295189_2	67352.JODS01000028_gene2341	1.258e-63	229.0	COG0438@1|root,COG0438@2|Bacteria,2I6NY@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_2295189_0	67352.JODS01000028_gene2344	9.229e-99	351.0	COG0438@1|root,COG0438@2|Bacteria,2GNR8@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	ko:K19424	-	-	-	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_2295189_1	530564.Psta_1247	6.827e-76	277.0	COG3118@1|root,COG3118@2|Bacteria,2J50V@203682|Planctomycetes	203682|Planctomycetes	O	ASPIC and UnbV	-	-	-	-	-	-	-	-	-	-	-	-	UnbV_ASPIC,VCBS
BYD2_k127_2295189_3	530564.Psta_1246	1.58e-43	175.0	COG3391@1|root,COG3391@2|Bacteria,2J1IA@203682|Planctomycetes	203682|Planctomycetes	S	amine dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2297750_3	1122247.C731_4793	1.394e-92	313.0	COG0318@1|root,COG0318@2|Bacteria,2IBED@201174|Actinobacteria,2370C@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_2297750_0	2002.JOEQ01000015_gene5076	2.062e-131	427.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,4EK30@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_2297750_2	1041522.MCOL_V205420	6.783e-98	340.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,238FA@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase carnithine racemase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_2297750_1	298654.FraEuI1c_5278	1.294e-124	404.0	COG1960@1|root,COG1960@2|Bacteria,2IBE0@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_2300949_1	1229780.BN381_10242	1.738e-89	316.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
BYD2_k127_2300949_4	649831.L083_7395	2.175e-24	112.0	COG1309@1|root,COG1309@2|Bacteria,2IEU9@201174|Actinobacteria,4DCCF@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2300949_0	1229780.BN381_290016	8.59e-102	337.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	ydaD	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_2300949_2	446462.Amir_5876	4.621e-49	185.0	COG0726@1|root,COG0726@2|Bacteria,2GPRN@201174|Actinobacteria,4DZAB@85010|Pseudonocardiales	201174|Actinobacteria	G	Polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
BYD2_k127_231704_10	645465.ACUR01000507_gene410	1.901e-31	134.0	COG0745@1|root,COG0745@2|Bacteria,2IQB8@201174|Actinobacteria	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Trans_reg_C
BYD2_k127_231704_8	1380356.JNIK01000013_gene4245	8.467e-40	161.0	COG0583@1|root,COG0583@2|Bacteria,2HGRW@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BYD2_k127_231704_7	1122247.C731_4197	4.271e-51	186.0	COG4044@1|root,COG4044@2|Bacteria,2IJGW@201174|Actinobacteria,238KG@1762|Mycobacteriaceae	201174|Actinobacteria	S	May play a role in the intracellular transport of hydrophobic ligands	-	-	-	-	-	-	-	-	-	-	-	-	DUF1794
BYD2_k127_231704_3	269800.Tfu_2911	1.058e-104	346.0	COG0588@1|root,COG0588@2|Bacteria,2GK8F@201174|Actinobacteria,4EFVY@85012|Streptosporangiales	201174|Actinobacteria	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmA	GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031323,GO:0031329,GO:0032787,GO:0032991,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0060255,GO:0062012,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031	5.4.2.11	ko:K01834	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko05230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map05230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	His_Phos_1
BYD2_k127_231704_0	1121877.JQKF01000011_gene362	1.044e-150	498.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria,4CMUZ@84992|Acidimicrobiia	84992|Acidimicrobiia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
BYD2_k127_231704_2	1229780.BN381_70019	8.698e-136	448.0	COG0768@1|root,COG0768@2|Bacteria,2GJUQ@201174|Actinobacteria,3UW84@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Penicillin binding protein transpeptidase domain	-	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
BYD2_k127_231704_1	1313172.YM304_02140	2.763e-138	473.0	COG0772@1|root,COG0772@2|Bacteria,2GJTI@201174|Actinobacteria,4CMWK@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell cycle protein	-	-	-	-	-	-	-	-	-	-	-	-	FTSW_RODA_SPOVE
BYD2_k127_231704_4	1229780.BN381_70017	9.695e-75	270.0	COG0631@1|root,COG0631@2|Bacteria,2GJ3M@201174|Actinobacteria,3UWNU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K01090,ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
BYD2_k127_231704_9	1229780.BN381_70016	5.289e-35	149.0	COG1716@1|root,COG1716@2|Bacteria,2GKA7@201174|Actinobacteria,3UWWG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Forkhead associated domain	fhaB	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl
BYD2_k127_231704_5	1229780.BN381_70015	8.355e-69	243.0	COG1716@1|root,COG1716@2|Bacteria,2GNU2@201174|Actinobacteria,3UWPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Protein of unknown function (DUF2662)	fhaA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363	-	-	-	-	-	-	-	-	-	-	DUF3662,FHA,Yop-YscD_cpl
BYD2_k127_231704_6	263358.VAB18032_24355	1.857e-57	225.0	COG4907@1|root,COG4907@2|Bacteria,2IBZ3@201174|Actinobacteria,4DBRQ@85008|Micromonosporales	201174|Actinobacteria	S	Predicted membrane protein (DUF2207)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2207
BYD2_k127_231704_11	1121007.AUML01000004_gene2496	8.326e-05	45.0	COG1961@1|root,COG1961@2|Bacteria,4P6RD@976|Bacteroidetes,1IC2M@117743|Flavobacteriia	976|Bacteroidetes	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2329106_8	395495.Lcho_2360	6.585e-23	115.0	COG5653@1|root,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,2VXRC@28216|Betaproteobacteria,1KN5M@119065|unclassified Burkholderiales	28216|Betaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
BYD2_k127_2329106_7	1121033.AUCF01000004_gene5071	2.628e-54	208.0	COG1247@1|root,COG1247@2|Bacteria	2|Bacteria	M	phosphinothricin N-acetyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
BYD2_k127_2329106_0	1120948.KB903243_gene2390	1.728e-194	634.0	COG1020@1|root,COG1020@2|Bacteria,2GP0R@201174|Actinobacteria,4E14R@85010|Pseudonocardiales	201174|Actinobacteria	Q	AMP-binding enzyme C-terminal domain	-	-	-	ko:K21780	ko00333,map00333	M00837,M00838	R06746	RC00039,RC01438	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_2329106_4	1120948.KB903243_gene2391	5.663e-128	417.0	COG2141@1|root,COG2141@2|Bacteria,2IDX7@201174|Actinobacteria,4EBHH@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
BYD2_k127_2329106_6	1121033.AUCF01000004_gene5068	3.368e-72	259.0	COG0223@1|root,COG0223@2|Bacteria,1N59R@1224|Proteobacteria,2UIHM@28211|Alphaproteobacteria,2JYNE@204441|Rhodospirillales	204441|Rhodospirillales	J	Formyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Formyl_trans_N
BYD2_k127_2329106_5	196162.Noca_2748	1.197e-107	366.0	COG0613@1|root,COG0613@2|Bacteria,2IDTP@201174|Actinobacteria	201174|Actinobacteria	S	PHP domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF3604
BYD2_k127_2329106_1	1229780.BN381_10012	9.435e-171	550.0	COG0460@1|root,COG0460@2|Bacteria,2GIX9@201174|Actinobacteria,3UWE2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Homoserine dehydrogenase	hom	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.1.1.3,2.7.2.4	ko:K00003,ko:K12524	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00017,M00018,M00526,M00527	R00480,R01773,R01775	RC00002,RC00043,RC00087	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1294	ACT,Homoserine_dh,NAD_binding_3
BYD2_k127_2329106_2	1296990.H845_571	4.451e-162	529.0	COG0498@1|root,COG0498@2|Bacteria,1MUWQ@1224|Proteobacteria,2TT0D@28211|Alphaproteobacteria,2JPG8@204441|Rhodospirillales	204441|Rhodospirillales	E	Threonine synthase	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP,Thr_synth_N
BYD2_k127_2329106_3	1229780.BN381_10014	5.054e-156	501.0	COG3635@1|root,COG3635@2|Bacteria,2IQCA@201174|Actinobacteria	201174|Actinobacteria	G	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
BYD2_k127_2329106_10	1229780.BN381_10016	1.108e-08	62.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,3UW70@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006351,GO:0006353,GO:0006360,GO:0006363,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0018130,GO:0019438,GO:0030312,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
BYD2_k127_2362775_1	266117.Rxyl_1586	1.169e-172	548.0	COG0620@1|root,COG0620@2|Bacteria,2I9RI@201174|Actinobacteria,4CPPJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Cobalamin-independent synthase, Catalytic domain	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
BYD2_k127_2362775_8	882083.SacmaDRAFT_2716	8.901e-89	304.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria,4E9TU@85010|Pseudonocardiales	201174|Actinobacteria	P	NMT1-like family	ssuA_3	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
BYD2_k127_2362775_7	1121933.AUHH01000003_gene1334	4.093e-118	386.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4DQPN@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2362775_3	1469613.JT55_07845	8.36e-157	521.0	COG0654@1|root,COG0654@2|Bacteria,1MV8T@1224|Proteobacteria,2TRB8@28211|Alphaproteobacteria	28211|Alphaproteobacteria	CH	4-hydroxybenzoate	pobA	-	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_3
BYD2_k127_2362775_6	1056512.D515_04448	7.233e-123	401.0	COG0673@1|root,COG0673@2|Bacteria,1MXUP@1224|Proteobacteria,1RP9K@1236|Gammaproteobacteria,1XW82@135623|Vibrionales	135623|Vibrionales	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.312	ko:K10219	ko00350,ko00362,ko00627,ko01120,ko01220,map00350,map00362,map00627,map01120,map01220	M00533	R04278,R04279,R04418,R04419	RC00251,RC00254	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA
BYD2_k127_2362775_11	1123023.JIAI01000009_gene1146	3.514e-52	191.0	COG1802@1|root,COG1802@2|Bacteria,2IBT4@201174|Actinobacteria,4E2PM@85010|Pseudonocardiales	201174|Actinobacteria	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
BYD2_k127_2362775_10	566466.NOR53_932	5.762e-69	255.0	COG2084@1|root,COG2084@2|Bacteria,1MX8V@1224|Proteobacteria,1RW94@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	-	-	-	-	-	-	-	-	-	-	-	-	DUF1932,NAD_binding_2
BYD2_k127_2362775_9	649831.L083_3805	5.264e-72	264.0	COG0684@1|root,COG0684@2|Bacteria,2I8VQ@201174|Actinobacteria,4DCVQ@85008|Micromonosporales	201174|Actinobacteria	H	Aldolase/RraA	ligK	-	4.1.3.17	ko:K10218	ko00362,ko00660,ko01120,map00362,map00660,map01120	-	R00008,R00350	RC00067,RC00502,RC01205	ko00000,ko00001,ko01000	-	-	-	RraA-like
BYD2_k127_2362775_2	1116375.VEJY3_18091	3.674e-169	538.0	COG2159@1|root,COG2159@2|Bacteria,1MVHB@1224|Proteobacteria,1RMYJ@1236|Gammaproteobacteria,1XVYI@135623|Vibrionales	135623|Vibrionales	S	Amidohydrolase	-	-	4.2.1.83	ko:K10220	ko00362,ko01120,map00362,map01120	-	R04478	RC00498	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
BYD2_k127_2362775_12	1190606.AJYG01000057_gene3865	1.744e-44	165.0	COG3384@1|root,COG3384@2|Bacteria,1RA8A@1224|Proteobacteria,1S8CE@1236|Gammaproteobacteria,1XZ81@135623|Vibrionales	135623|Vibrionales	S	Aromatic-ring-opening dioxygenase LigAB, LigA subunit	-	-	-	-	-	-	-	-	-	-	-	-	LigA
BYD2_k127_2362775_4	1123355.JHYO01000031_gene1598	9.643e-127	417.0	COG3384@1|root,COG3384@2|Bacteria,1MW77@1224|Proteobacteria,2TRP1@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Extradiol catechol dioxygenase that catalyzes the oxidative cleavage of substituted catechols	ligB	-	1.13.11.8	ko:K04101	ko00362,ko00624,ko00627,ko01120,map00362,map00624,map00627,map01120	-	R01632,R03550,R04280,R09565	RC00233,RC00387,RC00535,RC02567,RC02694	br01602,ko00000,ko00001,ko01000	-	-	-	LigB
BYD2_k127_2362775_5	68260.JOAY01000003_gene4488	1.745e-123	404.0	COG2897@1|root,COG2897@2|Bacteria,2GIYU@201174|Actinobacteria	201174|Actinobacteria	P	sulfurtransferase	-	-	2.8.1.1,2.8.1.2	ko:K01011	ko00270,ko00920,ko01100,ko01120,ko04122,map00270,map00920,map01100,map01120,map04122	-	R01931,R03105,R03106	RC00214	ko00000,ko00001,ko01000	-	-	-	Rhodanese
BYD2_k127_2362775_0	1312959.KI914644_gene1047	7.002e-184	586.0	COG5276@1|root,COG5276@2|Bacteria,2IAAZ@201174|Actinobacteria	201174|Actinobacteria	O	aminopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,P_proprotein
BYD2_k127_2379712_1	1283299.AUKG01000005_gene146	1.675e-35	152.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria,4CREI@84995|Rubrobacteria	84995|Rubrobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BYD2_k127_2379712_2	1454010.JEOE01000013_gene2276	1.084e-33	146.0	COG0845@1|root,COG0845@2|Bacteria,2H154@201174|Actinobacteria	201174|Actinobacteria	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005,ko:K13888	-	M00709	-	-	ko00000,ko00002,ko02000	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
BYD2_k127_2379712_0	675635.Psed_4503	5.395e-91	312.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DXK6@85010|Pseudonocardiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_2379712_3	408672.NBCG_05019	1.192e-30	123.0	COG0577@1|root,COG0577@2|Bacteria,2GIRW@201174|Actinobacteria,4DPWF@85009|Propionibacteriales	201174|Actinobacteria	V	MacB-like periplasmic core domain	yknZ	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_2389113_2	1229780.BN381_100166	1.436e-130	426.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,3UW7I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
BYD2_k127_2389113_1	1229780.BN381_100168	1.834e-138	450.0	COG0592@1|root,COG0592@2|Bacteria,2GJK3@201174|Actinobacteria,3UWB4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
BYD2_k127_2389113_4	1246445.ANAY01000036_gene1399	6.013e-82	286.0	COG1195@1|root,COG1195@2|Bacteria,2GJCS@201174|Actinobacteria,4EHXE@85012|Streptosporangiales	201174|Actinobacteria	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
BYD2_k127_2389113_5	1449069.JMLO01000026_gene2281	3.435e-37	145.0	COG4319@1|root,COG4319@2|Bacteria,2IKUP@201174|Actinobacteria,4G1CY@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
BYD2_k127_2389113_3	479432.Sros_2057	1.71e-83	287.0	COG1309@1|root,COG1309@2|Bacteria,2GIVD@201174|Actinobacteria,4EJM3@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2389113_6	1273125.Rrhod_2956	1.989e-06	54.0	COG5512@1|root,COG5512@2|Bacteria,2GNQ4@201174|Actinobacteria,4FUXM@85025|Nocardiaceae	201174|Actinobacteria	S	Belongs to the UPF0232 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF721
BYD2_k127_2389113_0	351607.Acel_0005	4.117e-152	493.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4ES0Z@85013|Frankiales	201174|Actinobacteria	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
BYD2_k127_2395537_9	1232429.CBLL010000160_gene623	0.000683	49.0	COG1409@1|root,COG1520@1|root,COG1409@2|Bacteria,COG1520@2|Bacteria,2H0VM@201174|Actinobacteria	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,PQQ_2
BYD2_k127_2395537_0	1206732.BAGD01000281_gene6568	2.775e-148	483.0	COG4106@1|root,COG4106@2|Bacteria,2I3QF@201174|Actinobacteria,4G039@85025|Nocardiaceae	201174|Actinobacteria	S	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
BYD2_k127_2395537_7	1246448.ANAZ01000019_gene968	8.844e-19	92.0	COG1765@1|root,COG1765@2|Bacteria,2IG8A@201174|Actinobacteria,4EKV5@85012|Streptosporangiales	201174|Actinobacteria	O	OsmC-like protein	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
BYD2_k127_2395537_1	1246448.ANAZ01000019_gene969	2.619e-133	445.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
BYD2_k127_2395537_4	479431.Namu_0023	1.26e-41	157.0	2BG65@1|root,32A2Y@2|Bacteria,2IRVF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2395537_2	134676.ACPL_3895	1.384e-93	333.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4DHH0@85008|Micromonosporales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
BYD2_k127_2395537_3	1179773.BN6_53060	1.2e-66	241.0	COG1366@1|root,COG1366@2|Bacteria,2II36@201174|Actinobacteria,4E3T4@85010|Pseudonocardiales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	MEDS,STAS_2
BYD2_k127_2395537_5	1120949.KB903313_gene508	5.745e-38	155.0	COG1309@1|root,COG1309@2|Bacteria,2I9F9@201174|Actinobacteria,4DEUA@85008|Micromonosporales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2395537_6	543632.JOJL01000024_gene1979	2.35e-30	136.0	COG5637@1|root,COG5637@2|Bacteria,2I3U7@201174|Actinobacteria,4DMM4@85008|Micromonosporales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_2395537_8	103733.JNYO01000039_gene4480	9.287e-10	70.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,4DZUJ@85010|Pseudonocardiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2404278_7	1463854.JOHT01000027_gene2503	3.436e-162	521.0	COG0277@1|root,COG0277@2|Bacteria,2GKQR@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cytokin-bind,FAD_binding_4
BYD2_k127_2404278_18	58344.JOEL01000015_gene6281	4.364e-69	257.0	COG2188@1|root,COG2188@2|Bacteria,2GKMH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
BYD2_k127_2404278_35	263358.VAB18032_13480	3.951e-23	105.0	COG1671@1|root,COG1671@2|Bacteria	2|Bacteria	S	Uncharacterized BCR, YaiI/YqxD family COG1671	yaiI	-	-	ko:K09768	-	-	-	-	ko00000	-	-	-	DUF188
BYD2_k127_2404278_5	263358.VAB18032_13485	1.834e-173	563.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4D9U7@85008|Micromonosporales	201174|Actinobacteria	P	Sulfate permease family	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
BYD2_k127_2404278_19	644283.Micau_2766	3.59e-63	235.0	COG0607@1|root,COG0607@2|Bacteria,2IB6H@201174|Actinobacteria,4D9CF@85008|Micromonosporales	201174|Actinobacteria	P	Protein of unknown function (DUF2892)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2892,Rhodanese
BYD2_k127_2404278_3	1229780.BN381_300001	5.14e-191	607.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria	201174|Actinobacteria	P	PFAM beta-lactamase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
BYD2_k127_2404278_29	1229780.BN381_130242	6.257e-31	123.0	COG1937@1|root,COG1937@2|Bacteria,2IQ7U@201174|Actinobacteria,3UWY5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metal-sensitive transcriptional repressor	csoR	-	-	-	-	-	-	-	-	-	-	-	Trns_repr_metal
BYD2_k127_2404278_24	1240349.ANGC01000010_gene2820	1.169e-46	171.0	COG3118@1|root,COG3118@2|Bacteria,2I2FB@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the thioredoxin family	-	-	1.8.1.9	ko:K00384,ko:K03671	ko00450,ko04621,ko05418,map00450,map04621,map05418	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000,ko03110	-	-	-	Thioredoxin
BYD2_k127_2404278_27	477641.MODMU_5086	4.085e-39	158.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BYD2_k127_2404278_25	208439.AJAP_14665	7.506e-45	168.0	COG3554@1|root,COG3554@2|Bacteria,2INM2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2404278_8	298654.FraEuI1c_5790	4.268e-151	486.0	COG0667@1|root,COG0667@2|Bacteria,2GMNA@201174|Actinobacteria,4EU12@85013|Frankiales	201174|Actinobacteria	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
BYD2_k127_2404278_30	28444.JODQ01000017_gene6538	9.715e-31	139.0	COG1302@1|root,COG1302@2|Bacteria,2GVSV@201174|Actinobacteria,4EPIY@85012|Streptosporangiales	201174|Actinobacteria	S	Asp23 family, cell envelope-related function	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
BYD2_k127_2404278_28	1229780.BN381_10159	6.252e-35	138.0	COG1848@1|root,COG1848@2|Bacteria,2GSP5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
BYD2_k127_2404278_11	439235.Dalk_0066	2.1e-132	452.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria,2MHUE@213118|Desulfobacterales	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
BYD2_k127_2404278_33	446468.Ndas_1111	3.401e-25	121.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EJD9@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
BYD2_k127_2404278_26	479431.Namu_1714	1.97e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,2GP92@201174|Actinobacteria,4ETB6@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2404278_14	397278.JOJN01000002_gene372	1.42e-82	289.0	COG1131@1|root,COG1131@2|Bacteria,2I2I7@201174|Actinobacteria,4DQ62@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_2404278_15	479433.Caci_5571	7.812e-79	270.0	COG0842@1|root,COG0842@2|Bacteria,2GJ7Y@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01990,ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_2404278_2	675635.Psed_6375	1.7e-204	640.0	COG0409@1|root,COG0409@2|Bacteria,2GMHA@201174|Actinobacteria,4DYZ6@85010|Pseudonocardiales	201174|Actinobacteria	O	hydrogenase expression formation protein HypD	hypD	-	-	ko:K04654	-	-	-	-	ko00000	-	-	-	HypD
BYD2_k127_2404278_10	1078020.KEK_10973	2.919e-135	454.0	COG0309@1|root,COG0309@2|Bacteria,2GJ7N@201174|Actinobacteria,232GN@1762|Mycobacteriaceae	201174|Actinobacteria	O	hydrogenase expression formation protein HypE	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
BYD2_k127_2404278_20	935866.JAER01000029_gene1441	7.195e-61	224.0	COG0279@1|root,COG0279@2|Bacteria,2GM2Q@201174|Actinobacteria,4DS8W@85009|Propionibacteriales	201174|Actinobacteria	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
BYD2_k127_2404278_21	1150599.MPHLEI_15441	8.345e-60	222.0	COG0279@1|root,COG0279@2|Bacteria,2GMKE@201174|Actinobacteria,2349G@1762|Mycobacteriaceae	201174|Actinobacteria	G	HupF/HypC family	-	-	-	-	-	-	-	-	-	-	-	-	HupF_HypC
BYD2_k127_2404278_36	326427.Cagg_0478	5.214e-21	108.0	COG0298@1|root,COG0298@2|Bacteria,2G7GW@200795|Chloroflexi,377Q5@32061|Chloroflexia	32061|Chloroflexia	O	PFAM hydrogenase expression formation protein (HUPF HYPC)	-	-	-	ko:K04653	-	-	-	-	ko00000	-	-	-	HupF_HypC
BYD2_k127_2404278_0	469371.Tbis_3230	1.687e-265	841.0	COG0068@1|root,COG0068@2|Bacteria,2GJYF@201174|Actinobacteria,4DYVA@85010|Pseudonocardiales	201174|Actinobacteria	O	Belongs to the carbamoyltransferase HypF family	hypF	-	-	ko:K04656	-	-	-	-	ko00000	-	-	-	Acylphosphatase,Sua5_yciO_yrdC,zf-HYPF
BYD2_k127_2404278_37	926560.KE387023_gene1933	4.435e-12	78.0	COG5624@1|root,COG5624@2|Bacteria,1WJK4@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	K	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2404278_4	1108045.GORHZ_080_00080	6.774e-190	615.0	COG0842@1|root,COG1131@1|root,COG0842@2|Bacteria,COG1131@2|Bacteria,2GKEU@201174|Actinobacteria,4GBVK@85026|Gordoniaceae	201174|Actinobacteria	V	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	ko:K01990,ko:K21397	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC_tran,FHA,Yop-YscD_cpl
BYD2_k127_2404278_23	1043493.BBLU01000003_gene2496	5.277e-55	217.0	COG4977@1|root,COG4977@2|Bacteria,2GM0M@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
BYD2_k127_2404278_9	1435356.Y013_05145	3.014e-136	450.0	2DBMA@1|root,2Z9Y3@2|Bacteria,2I9ER@201174|Actinobacteria,4FWK9@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF4389)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4389
BYD2_k127_2404278_6	1229780.BN381_110006	3.546e-173	569.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_2404278_22	326424.FRAAL2901	3.743e-59	217.0	COG2227@1|root,COG2227@2|Bacteria,2IIRY@201174|Actinobacteria	201174|Actinobacteria	H	Thiopurine S-methyltransferase (TPMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_2404278_32	43759.JNWK01000111_gene382	1.411e-28	119.0	COG0640@1|root,COG0640@2|Bacteria,2IMCE@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_2404278_16	1306990.BARG01000083_gene8389	9.059e-74	261.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
BYD2_k127_2404278_17	1056816.JAFQ01000004_gene814	6.16e-73	269.0	COG3509@1|root,COG3509@2|Bacteria,2GNV6@201174|Actinobacteria,4FU2W@85025|Nocardiaceae	201174|Actinobacteria	Q	Esterase PHB depolymerase	-	-	-	ko:K03932	-	-	-	-	ko00000	-	CE1	-	Esterase_phd
BYD2_k127_2404278_1	247156.NFA_43520	9.511e-229	713.0	COG1960@1|root,COG1960@2|Bacteria,2GJX5@201174|Actinobacteria,4FXG8@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE12_3	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_2404278_13	2074.JNYD01000031_gene6583	9.581e-91	325.0	COG1024@1|root,COG1024@2|Bacteria,2H25N@201174|Actinobacteria,4EBYU@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_2404278_12	2074.JNYD01000031_gene6587	2.072e-122	407.0	COG3173@1|root,COG3173@2|Bacteria,2HU7E@201174|Actinobacteria,4DYKS@85010|Pseudonocardiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_2404278_34	1194972.MVAC_08754	4.192e-25	121.0	28M2T@1|root,2ZAH6@2|Bacteria,2H696@201174|Actinobacteria,237M6@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2404278_38	1125971.ASJB01000069_gene473	1.986e-11	69.0	COG1309@1|root,COG1309@2|Bacteria,2GQ1K@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2404278_31	1120950.KB892796_gene2243	6.646e-29	120.0	COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria,4DSPB@85009|Propionibacteriales	201174|Actinobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
BYD2_k127_2426586_9	298655.KI912266_gene2835	2.279e-47	191.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2ICGU@201174|Actinobacteria	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
BYD2_k127_2426586_7	298655.KI912266_gene2834	1.3e-86	295.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_2426586_3	1313172.YM304_24680	1.494e-140	455.0	COG2230@1|root,COG2230@2|Bacteria,2H060@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
BYD2_k127_2426586_1	446468.Ndas_1353	1.536e-169	546.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,2GJB4@201174|Actinobacteria,4EG8R@85012|Streptosporangiales	201174|Actinobacteria	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
BYD2_k127_2426586_6	247634.GPB2148_1962	3.062e-94	323.0	COG0121@1|root,COG0121@2|Bacteria,1Q80V@1224|Proteobacteria,1SN0H@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Phosphoinositide phospholipase C, Ca2+-dependent	-	-	-	-	-	-	-	-	-	-	-	-	PI-PLC-C1
BYD2_k127_2426586_0	1229780.BN381_20132	1.677e-171	555.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,3UXHK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
BYD2_k127_2426586_5	1229780.BN381_20133	7e-105	353.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,3UXS5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
BYD2_k127_2426586_8	1229780.BN381_50087	6.939e-83	288.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,3UWXI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
BYD2_k127_2426586_2	1120936.KB907209_gene1792	2.283e-141	474.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
BYD2_k127_2426586_4	1229780.BN381_50085	4.5e-136	461.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,3UX3T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
BYD2_k127_2426586_11	208444.JNYY01000033_gene5837	4.059e-15	83.0	COG1309@1|root,COG1309@2|Bacteria,2IGE6@201174|Actinobacteria,4E2XV@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2426586_10	1463856.JOHY01000003_gene5237	2.384e-22	100.0	COG4974@1|root,COG4974@2|Bacteria,2HD2H@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_2439650_10	306281.AJLK01000102_gene3405	4.192e-67	234.0	COG2258@1|root,COG2258@2|Bacteria,1GE7I@1117|Cyanobacteria	1117|Cyanobacteria	S	MOSC domain	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2439650_14	1120948.KB903243_gene2394	1.327e-48	195.0	2E29A@1|root,30QXH@2|Bacteria,2H74E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2439650_12	1340493.JNIF01000003_gene3428	2.477e-59	213.0	COG2207@1|root,COG2207@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_2439650_11	1122138.AQUZ01000023_gene7839	3.956e-60	219.0	COG0262@1|root,COG0262@2|Bacteria,2IFCY@201174|Actinobacteria,4DWQI@85009|Propionibacteriales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_2439650_2	1380386.JIAW01000005_gene1435	4.611e-153	489.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,237Y2@1762|Mycobacteriaceae	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_2439650_8	1123023.JIAI01000003_gene2891	5.681e-69	254.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria,4E70D@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_2439650_13	1304865.JAGF01000001_gene36	6.768e-53	192.0	COG4430@1|root,COG4430@2|Bacteria,2IN25@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
BYD2_k127_2439650_18	497964.CfE428DRAFT_4343	1.304e-08	59.0	COG0662@1|root,COG0662@2|Bacteria	2|Bacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_2439650_19	1267535.KB906767_gene2265	1.163e-07	63.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_2439650_20	1463857.JOFZ01000001_gene5811	1.31e-06	59.0	COG2442@1|root,COG2442@2|Bacteria,2IJ8Q@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF433)	-	-	-	-	-	-	-	-	-	-	-	-	DUF433,MerR_1
BYD2_k127_2439650_17	888056.HMPREF9062_0641	2.787e-40	154.0	COG0454@1|root,COG0456@2|Bacteria,2IMVD@201174|Actinobacteria,4D5W9@85005|Actinomycetales	201174|Actinobacteria	K	(GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_2439650_4	67373.JOBF01000016_gene4962	1.594e-143	475.0	COG0372@1|root,COG0372@2|Bacteria,2GKST@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the citrate synthase family	citA	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
BYD2_k127_2439650_6	1298863.AUEP01000005_gene2353	2.597e-77	269.0	COG1938@1|root,COG1938@2|Bacteria,2GK10@201174|Actinobacteria,4DNMH@85009|Propionibacteriales	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
BYD2_k127_2439650_0	1229780.BN381_290013	1.392e-174	562.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	2|Bacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
BYD2_k127_2439650_15	457425.XNR_4118	1.518e-46	182.0	COG0628@1|root,COG0628@2|Bacteria,2GK0H@201174|Actinobacteria	201174|Actinobacteria	D	permease	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
BYD2_k127_2439650_5	42256.RradSPS_2551	1.325e-103	376.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4CQDA@84995|Rubrobacteria	84995|Rubrobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BYD2_k127_2439650_9	1229780.BN381_310079	2.362e-68	250.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,3UXS8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	yvhJ	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
BYD2_k127_2439650_16	710685.MycrhN_0150	4.398e-44	185.0	COG4221@1|root,COG4221@2|Bacteria,2IFSP@201174|Actinobacteria,23966@1762|Mycobacteriaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_2439650_7	1123320.KB889585_gene1873	4.144e-70	249.0	COG1960@1|root,COG1960@2|Bacteria,2GK9C@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE27	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
BYD2_k127_2439650_1	1123320.KB889585_gene1872	7.814e-171	546.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_2439650_3	298655.KI912266_gene5765	2.393e-150	486.0	COG0318@1|root,COG0318@2|Bacteria,2IBED@201174|Actinobacteria,4EU08@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_2456431_0	1896.JOAU01000012_gene586	3.925e-81	276.0	COG0376@1|root,COG0376@2|Bacteria,2GJFP@201174|Actinobacteria	201174|Actinobacteria	P	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity	katG	-	1.11.1.21	ko:K03782	ko00360,ko00380,ko00940,ko00983,ko01100,ko01110,map00360,map00380,map00940,map00983,map01100,map01110	-	R00602,R00698,R02596,R02670,R03919,R04007,R07443,R11906	RC00034,RC00213,RC00767,RC02141	ko00000,ko00001,ko01000	-	-	-	peroxidase
BYD2_k127_2456431_1	469383.Cwoe_2725	9.725e-60	209.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,4CTCG@84995|Rubrobacteria	84995|Rubrobacteria	P	Ferric uptake regulator family	-	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
BYD2_k127_2456431_4	1463921.JODF01000027_gene6372	1.886e-26	114.0	COG2128@1|root,COG2128@2|Bacteria,2I9B5@201174|Actinobacteria	201174|Actinobacteria	S	carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_2456431_2	1298863.AUEP01000011_gene587	5.724e-46	177.0	COG5486@1|root,COG5486@2|Bacteria	2|Bacteria	S	Metal-binding integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
BYD2_k127_2456431_3	1298863.AUEP01000011_gene586	5.385e-29	120.0	2DBCY@1|root,2Z8GH@2|Bacteria	2|Bacteria	S	PFAM Tyrosinase	-	-	1.10.3.1,1.14.18.1	ko:K00422,ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00031,R00045,R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	PPO1_DWL,PPO1_KFDV,Tyrosinase
BYD2_k127_2465891_1	1313172.YM304_33140	4.143e-117	402.0	COG1694@1|root,COG3956@2|Bacteria,2GNKC@201174|Actinobacteria,4CN31@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	ko:K02499	-	-	-	-	ko00000,ko03036	-	-	-	MazG
BYD2_k127_2465891_0	1313172.YM304_33170	2.669e-195	617.0	COG0148@1|root,COG0148@2|Bacteria,2GJAY@201174|Actinobacteria,4CMRI@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
BYD2_k127_2466355_2	521674.Plim_3874	2.488e-21	109.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,2J0AY@203682|Planctomycetes	203682|Planctomycetes	D	Capsular exopolysaccharide family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31,Wzz
BYD2_k127_2466355_0	1348663.KCH_16860	1.58e-109	382.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria,2M4SG@2063|Kitasatospora	201174|Actinobacteria	E	DegT DnrJ EryC1 StrS aminotransferase family	eryCIV	GO:0005575,GO:0005576,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009607,GO:0009987,GO:0009991,GO:0010106,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042592,GO:0042594,GO:0043207,GO:0044403,GO:0044419,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071496,GO:0075136,GO:0098771	2.6.1.33	ko:K13308	ko00523,ko01130,map00523,map01130	M00797	R02773	RC00006,RC00781	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
BYD2_k127_2466355_1	314230.DSM3645_07985	2.865e-24	110.0	COG0451@1|root,COG0451@2|Bacteria,2IYGP@203682|Planctomycetes	203682|Planctomycetes	M	PFAM NAD dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
BYD2_k127_2484742_30	1297570.MESS4_750310	8.977e-05	49.0	COG0500@1|root,COG2226@2|Bacteria,1N5QH@1224|Proteobacteria,2UM5M@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
BYD2_k127_2484742_12	631454.N177_2111	6.855e-48	190.0	COG1280@1|root,COG1280@2|Bacteria,1MXAI@1224|Proteobacteria,2TQWG@28211|Alphaproteobacteria,1JPMT@119043|Rhodobiaceae	28211|Alphaproteobacteria	E	LysE type translocator	MA20_04860	-	-	-	-	-	-	-	-	-	-	-	LysE
BYD2_k127_2484742_22	103733.JNYO01000014_gene3764	6.901e-28	119.0	COG1695@1|root,COG1695@2|Bacteria,2IQ70@201174|Actinobacteria,4E6C0@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
BYD2_k127_2484742_29	1121926.AXWO01000007_gene202	1.643e-05	49.0	COG0286@1|root,COG0286@2|Bacteria,2IBQ1@201174|Actinobacteria	201174|Actinobacteria	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
BYD2_k127_2484742_18	1229780.BN381_350150	1.886e-36	141.0	COG3536@1|root,COG3536@2|Bacteria,2HDP4@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF971)	-	-	-	-	-	-	-	-	-	-	-	-	DUF971
BYD2_k127_2484742_7	106370.Francci3_0222	2.738e-97	329.0	COG2267@1|root,COG2267@2|Bacteria,2I94I@201174|Actinobacteria,4EU87@85013|Frankiales	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_2484742_9	1242864.D187_008170	2.051e-92	313.0	COG2378@1|root,COG2378@2|Bacteria,1PXCX@1224|Proteobacteria,42V48@68525|delta/epsilon subdivisions,2WPJT@28221|Deltaproteobacteria	28221|Deltaproteobacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
BYD2_k127_2484742_2	1229780.BN381_290124	4.63e-189	619.0	COG1012@1|root,COG1012@2|Bacteria,2GJ95@201174|Actinobacteria,3UWDK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	gabD2	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009013,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	1.2.1.16,1.2.1.20,1.2.1.79	ko:K00135	ko00250,ko00310,ko00350,ko00650,ko00760,ko01100,ko01120,map00250,map00310,map00350,map00650,map00760,map01100,map01120	M00027	R00713,R00714,R02401	RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_2484742_3	909613.UO65_2457	3.37e-176	572.0	COG5267@1|root,COG5267@2|Bacteria,2I8YT@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1800
BYD2_k127_2484742_5	909613.UO65_2456	2.361e-128	422.0	COG4102@1|root,COG4102@2|Bacteria,2GJWB@201174|Actinobacteria,4E24Q@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1501
BYD2_k127_2484742_24	1121413.JMKT01000009_gene2170	2.957e-23	106.0	COG0361@1|root,COG0361@2|Bacteria,1MZFU@1224|Proteobacteria,42TRU@68525|delta/epsilon subdivisions,2WPZK@28221|Deltaproteobacteria,2MCF7@213115|Desulfovibrionales	28221|Deltaproteobacteria	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
BYD2_k127_2484742_23	1229780.BN381_290029	1.015e-25	111.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria,3UWUK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	'Cold-shock' DNA-binding domain	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
BYD2_k127_2484742_20	1121877.JQKF01000017_gene178	1.615e-32	135.0	COG1595@1|root,COG1595@2|Bacteria,2HG3F@201174|Actinobacteria,4CP1C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_2484742_1	1127134.NOCYR_3228	5.029e-198	642.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,2GMN4@201174|Actinobacteria,4FX0N@85025|Nocardiaceae	201174|Actinobacteria	GT	Pyruvate phosphate dikinase, PEP/pyruvate binding domain	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
BYD2_k127_2484742_14	1127134.NOCYR_3227	1.891e-44	168.0	2FHIX@1|root,349CW@2|Bacteria,2GN7H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2484742_11	1229780.BN381_80064	5.491e-74	262.0	COG2265@1|root,COG2265@2|Bacteria,2GIR3@201174|Actinobacteria,3UWPY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
BYD2_k127_2484742_8	1229780.BN381_80063	5.818e-96	319.0	COG0036@1|root,COG0036@2|Bacteria,2GJZ9@201174|Actinobacteria,3UWJU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Ribulose-phosphate 3 epimerase family	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
BYD2_k127_2484742_10	1229780.BN381_80062	2.441e-83	282.0	COG0740@1|root,COG0740@2|Bacteria,2GK5C@201174|Actinobacteria,3UWHQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
BYD2_k127_2484742_17	1449976.KALB_2627	1.236e-36	160.0	COG3179@1|root,COG5640@1|root,COG3179@2|Bacteria,COG5640@2|Bacteria,2I1PP@201174|Actinobacteria,4EDFP@85010|Pseudonocardiales	2|Bacteria	O	chitinase	-	-	-	ko:K03791,ko:K14645,ko:K17733	ko02024,map02024	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011,ko03110	-	GH19	-	Glyco_hydro_19,PG_binding_1
BYD2_k127_2484742_26	1249627.D779_2366	1.141e-21	111.0	COG1680@1|root,COG1680@2|Bacteria	2|Bacteria	V	peptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2484742_25	1122179.KB890452_gene4643	2.839e-22	113.0	COG0739@1|root,COG0739@2|Bacteria,4NEBZ@976|Bacteroidetes,1IWGS@117747|Sphingobacteriia	976|Bacteroidetes	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23,SH3_3,SH3_4
BYD2_k127_2484742_4	287986.DV20_32790	5.198e-149	481.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DY4T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA primase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2484742_21	656024.FsymDg_0590	2.969e-29	122.0	2FCKD@1|root,344PQ@2|Bacteria,2GVQX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2484742_0	351607.Acel_1394	0.0	1195.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,4ESAU@85013|Frankiales	201174|Actinobacteria	C	Aconitate hydratase 1	acnA	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
BYD2_k127_2484742_16	1121439.dsat_0772	1.528e-41	169.0	COG0127@1|root,COG0127@2|Bacteria,1MUK5@1224|Proteobacteria,42NGT@68525|delta/epsilon subdivisions,2WK3E@28221|Deltaproteobacteria,2MB1P@213115|Desulfovibrionales	28221|Deltaproteobacteria	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	iAF987.Gmet_1875	Ham1p_like
BYD2_k127_2484742_6	1313172.YM304_27700	1.757e-105	347.0	COG0689@1|root,COG0689@2|Bacteria,2GJFI@201174|Actinobacteria,4CMXE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates	rph	-	2.7.7.56	ko:K00989	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RNase_PH,RNase_PH_C
BYD2_k127_2484742_15	1229780.BN381_80057	5.538e-44	170.0	COG1234@1|root,COG1234@2|Bacteria,2HNMK@201174|Actinobacteria,3UXIJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
BYD2_k127_2484742_13	1333998.M2A_2494	5.048e-46	182.0	2EXDM@1|root,33QQ7@2|Bacteria,1NTQ6@1224|Proteobacteria,2UQVJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2484742_19	1313172.YM304_31780	7.152e-35	153.0	COG2119@1|root,COG2119@2|Bacteria,2GNR0@201174|Actinobacteria	201174|Actinobacteria	O	membrane	-	-	-	-	-	-	-	-	-	-	-	-	UPF0016
BYD2_k127_2506610_16	1313172.YM304_07200	6.006e-38	149.0	COG1716@1|root,COG2114@1|root,COG1716@2|Bacteria,COG2114@2|Bacteria,2I8W5@201174|Actinobacteria	201174|Actinobacteria	T	COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain)	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
BYD2_k127_2506610_15	1229780.BN381_630015	7.364e-49	180.0	COG1507@1|root,COG1507@2|Bacteria,2I8CS@201174|Actinobacteria,3UWSU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF501)	-	-	-	ko:K09009	-	-	-	-	ko00000	-	-	-	DUF501
BYD2_k127_2506610_11	1155714.KB891996_gene3476	7.226e-81	287.0	COG0248@1|root,COG1507@1|root,COG0248@2|Bacteria,COG1507@2|Bacteria,2GJBN@201174|Actinobacteria	201174|Actinobacteria	FP	Ppx GppA phosphatase	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	Ppx-GppA
BYD2_k127_2506610_1	1380347.JNII01000008_gene4090	4.952e-158	505.0	COG0075@1|root,COG0075@2|Bacteria,2H16A@201174|Actinobacteria	201174|Actinobacteria	E	Serine-pyruvate aminotransferase archaeal aspartate aminotransferase	agxT	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
BYD2_k127_2506610_12	1313172.YM304_33450	4.594e-55	221.0	COG1670@1|root,COG1670@2|Bacteria,2HFKU@201174|Actinobacteria,4CP4F@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
BYD2_k127_2506610_17	1229780.BN381_220032	2.116e-30	131.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
BYD2_k127_2506610_22	1283299.AUKG01000001_gene2158	4.765e-14	74.0	2B8TX@1|root,32240@2|Bacteria,2HRST@201174|Actinobacteria,4CTW1@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2506610_10	1313172.YM304_33510	2.73e-86	295.0	COG1024@1|root,COG1024@2|Bacteria,2H2G7@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA14	GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_2506610_19	1313172.YM304_34030	2.92e-27	117.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_2506610_18	1246445.ANAY01000047_gene2667	2.422e-27	129.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4EI14@85012|Streptosporangiales	201174|Actinobacteria	K	Cell envelope-related transcriptional attenuator domain	yvhJ	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
BYD2_k127_2506610_13	1229780.BN381_90069	5e-49	192.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
BYD2_k127_2506610_14	1229780.BN381_90069	6.753e-49	192.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
BYD2_k127_2506610_5	1229780.BN381_630011	2.166e-132	443.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,3UWTN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	NAD dependent epimerase/dehydratase family	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
BYD2_k127_2506610_8	1229780.BN381_630010	1.296e-99	338.0	COG0204@1|root,COG0204@2|Bacteria,2GJKH@201174|Actinobacteria,3UXD2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Phosphate acyltransferases	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Acyltransferase
BYD2_k127_2506610_21	1313172.YM304_32820	2.644e-14	76.0	2CK2C@1|root,2ZY21@2|Bacteria,2HE72@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2506610_6	1229780.BN381_10328	4.454e-122	409.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,3UX6E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
BYD2_k127_2506610_4	1229780.BN381_70077	8.172e-143	467.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria	201174|Actinobacteria	Q	diacylglycerol O-acyltransferase	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
BYD2_k127_2506610_3	1313172.YM304_21460	1.335e-144	470.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CN10@84992|Acidimicrobiia	201174|Actinobacteria	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
BYD2_k127_2506610_2	1313172.YM304_21470	9.539e-152	496.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4CN10@84992|Acidimicrobiia	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
BYD2_k127_2506610_7	67356.KL575603_gene6771	1.662e-113	381.0	COG5549@1|root,COG5549@2|Bacteria,2I9HV@201174|Actinobacteria	201174|Actinobacteria	O	Zinc-dependent metalloprotease	-	-	-	-	-	-	-	-	-	-	-	-	Astacin
BYD2_k127_2506610_0	1394178.AWOO02000017_gene6792	5.842e-211	659.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria,4EN8T@85012|Streptosporangiales	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_2506610_20	337191.KTR9_3738	1.741e-19	93.0	COG0535@1|root,COG0535@2|Bacteria,2GQQT@201174|Actinobacteria,4GF04@85026|Gordoniaceae	201174|Actinobacteria	S	Mycofactocin system	mftB	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2506610_9	1206744.BAGL01000127_gene7070	1.463e-95	319.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria,4FWJS@85025|Nocardiaceae	201174|Actinobacteria	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
BYD2_k127_2507313_0	1463934.JOCF01000061_gene3287	5.323e-38	145.0	COG0583@1|root,COG0657@1|root,COG0583@2|Bacteria,COG0657@2|Bacteria,2I8XP@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3,HTH_1
BYD2_k127_2507313_1	446471.Xcel_3289	3.851e-27	122.0	COG2353@1|root,COG2353@2|Bacteria,2IM4N@201174|Actinobacteria,4F4I6@85017|Promicromonosporaceae	201174|Actinobacteria	S	YceI-like domain	-	-	-	-	-	-	-	-	-	-	-	-	YceI
BYD2_k127_2522715_0	675635.Psed_3915	3.134e-143	467.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4E1N9@85010|Pseudonocardiales	201174|Actinobacteria	L	PFAM Transposase, IS111A IS1328 IS1533, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
BYD2_k127_2530283_1	525368.HMPREF0591_0754	3.562e-91	305.0	COG4638@1|root,COG4638@2|Bacteria,2GM3P@201174|Actinobacteria,233JP@1762|Mycobacteriaceae	201174|Actinobacteria	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
BYD2_k127_2530283_0	749927.AMED_7139	3.829e-231	728.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria,4E0RS@85010|Pseudonocardiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	1.14.13.22,1.14.13.226	ko:K03379,ko:K18371	ko00640,ko00930,ko01120,ko01220,map00640,map00930,map01120,map01220	-	R02231,R06622,R10704	RC00662,RC01550,RC03250	ko00000,ko00001,ko01000	-	-	-	FMO-like,Pyr_redox_2,Pyr_redox_3
BYD2_k127_2574024_3	875328.JDM601_4190	7.594e-68	260.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,23435@1762|Mycobacteriaceae	201174|Actinobacteria	EI	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BYD2_k127_2574024_4	1122939.ATUD01000002_gene1205	4.77e-52	208.0	COG0705@1|root,COG0705@2|Bacteria,2GJYG@201174|Actinobacteria,4CQ6Z@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
BYD2_k127_2574024_0	321327.CYA_1973	1.25e-150	506.0	COG1449@1|root,COG1449@2|Bacteria,1G0BM@1117|Cyanobacteria,1GYNP@1129|Synechococcus	1117|Cyanobacteria	G	Belongs to the glycosyl hydrolase 57 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF3536,Glyco_hydro_57
BYD2_k127_2574024_2	1122138.AQUZ01000015_gene6845	1.462e-68	249.0	COG0477@1|root,COG2814@2|Bacteria,2I8HS@201174|Actinobacteria,4DVK7@85009|Propionibacteriales	201174|Actinobacteria	EGP	Sugar (and other) transporter	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_1_like,Sugar_tr
BYD2_k127_2574024_1	1123257.AUFV01000001_gene1903	6.82e-71	244.0	COG0296@1|root,COG0296@2|Bacteria,1QTVN@1224|Proteobacteria,1RQSK@1236|Gammaproteobacteria,1X555@135614|Xanthomonadales	135614|Xanthomonadales	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB1	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
BYD2_k127_2575910_4	1313172.YM304_24920	3.293e-77	263.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CMZU@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
BYD2_k127_2575910_11	1151119.KB895491_gene1840	8.817e-17	84.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	-	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
BYD2_k127_2575910_7	298655.KI912267_gene7279	1.124e-63	229.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4ESC1@85013|Frankiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_2575910_1	1206720.BAFQ01000281_gene5906	5.686e-110	362.0	COG2220@1|root,COG2220@2|Bacteria,2IT2Z@201174|Actinobacteria,4FXF0@85025|Nocardiaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_3
BYD2_k127_2575910_8	1449069.JMLO01000018_gene596	1.634e-61	218.0	COG1024@1|root,COG1024@2|Bacteria,2IP2B@201174|Actinobacteria,4G2VY@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_2575910_0	457429.ABJI02000346_gene6157	2.944e-115	382.0	COG0180@1|root,COG0180@2|Bacteria,2GJ9A@201174|Actinobacteria	201174|Actinobacteria	J	Tryptophanyl-tRNA synthetase	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
BYD2_k127_2575910_3	1229780.BN381_290072	6.339e-91	310.0	COG1354@1|root,COG1354@2|Bacteria,2GN1U@201174|Actinobacteria,3UWJ9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
BYD2_k127_2575910_5	1229780.BN381_290071	7.011e-71	249.0	COG1386@1|root,COG1386@2|Bacteria,2GISY@201174|Actinobacteria,3UWQK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
BYD2_k127_2575910_2	1229780.BN381_290070	3.448e-95	318.0	COG1187@1|root,COG1187@2|Bacteria,2GJ4N@201174|Actinobacteria,3UWKC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	RNA pseudouridylate synthase	rluB	GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	5.4.99.19,5.4.99.22	ko:K06178,ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
BYD2_k127_2575910_9	1229780.BN381_290069	6.165e-51	183.0	COG4401@1|root,COG4401@2|Bacteria,2IHWT@201174|Actinobacteria,3UXJE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Chorismate mutase type I	-	-	5.4.99.5	ko:K06208	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_1
BYD2_k127_2575910_6	1313172.YM304_24990	1.696e-65	231.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CNBS@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
BYD2_k127_2587078_7	1313172.YM304_12570	6.078e-22	113.0	2CDEB@1|root,2ZRID@2|Bacteria,2HDK8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2587078_4	1313172.YM304_12580	4.805e-52	207.0	COG0620@1|root,COG0620@2|Bacteria	2|Bacteria	E	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation	-	-	2.1.1.14	ko:K00549	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	M00017	R04405,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Meth_synt_2
BYD2_k127_2587078_0	1229780.BN381_10084	7.065e-256	806.0	COG0272@1|root,COG0272@2|Bacteria,2GJUY@201174|Actinobacteria,3UW7F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
BYD2_k127_2587078_2	1313172.YM304_12630	5.673e-81	296.0	COG0515@1|root,COG2815@1|root,COG0515@2|Bacteria,COG2815@2|Bacteria,2GJ1J@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase,Pkinase_Tyr
BYD2_k127_2587078_5	1229780.BN381_10089	4.237e-32	132.0	COG3255@1|root,COG3255@2|Bacteria,2H0GP@201174|Actinobacteria	201174|Actinobacteria	I	Sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2587078_8	1229780.BN381_140034	1.473e-15	90.0	COG1309@1|root,COG1309@2|Bacteria,2GXGA@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2587078_3	1313172.YM304_33890	4.919e-63	226.0	COG1647@1|root,COG1647@2|Bacteria,2GM1Y@201174|Actinobacteria	201174|Actinobacteria	S	Esterase	yvaK	-	3.1.1.1	ko:K03928	-	-	-	-	ko00000,ko01000	-	-	-	Hydrolase_4
BYD2_k127_2587078_6	1137268.AZXF01000010_gene2790	2.836e-24	106.0	COG0721@1|root,COG0721@2|Bacteria,2IQJN@201174|Actinobacteria,4EJUI@85012|Streptosporangiales	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
BYD2_k127_2587078_1	1229780.BN381_10093	3.926e-186	604.0	COG0154@1|root,COG0154@2|Bacteria,2GJK5@201174|Actinobacteria,3UWA6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	GO:0008150,GO:0040007	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
BYD2_k127_2587078_9	749414.SBI_04978	3.621e-13	69.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone reductase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_2587949_2	1122176.KB903531_gene3019	3.28e-51	196.0	COG1680@1|root,COG1680@2|Bacteria,4NEVS@976|Bacteroidetes	976|Bacteroidetes	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_2587949_1	1229780.BN381_290011	1.123e-82	284.0	COG2375@1|root,COG2375@2|Bacteria,2HEWI@201174|Actinobacteria,3UWVN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Siderophore-interacting FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
BYD2_k127_2587949_0	1380390.JIAT01000010_gene3581	3.778e-179	576.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4CS1B@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
BYD2_k127_2587949_3	1380390.JIAT01000010_gene3582	8.04e-48	173.0	COG3795@1|root,COG3795@2|Bacteria,2IQKK@201174|Actinobacteria,4CTDA@84995|Rubrobacteria	84995|Rubrobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_2587949_4	504472.Slin_3264	9.883e-41	156.0	COG0262@1|root,COG0262@2|Bacteria,4NSY9@976|Bacteroidetes,47XF5@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_2598257_0	471852.Tcur_1029	0.0	1485.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,2GM65@201174|Actinobacteria,4EHBK@85012|Streptosporangiales	201174|Actinobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0047727,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564	5.4.99.13,5.4.99.2	ko:K01848,ko:K11942	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00375,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
BYD2_k127_2598257_26	28042.GU90_18260	3.96e-51	186.0	COG1846@1|root,COG1846@2|Bacteria,2GKZA@201174|Actinobacteria,4DXV5@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
BYD2_k127_2598257_4	1229780.BN381_210077	2.609e-236	753.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_2598257_16	1211815.CBYP010000042_gene2406	6.158e-100	336.0	COG5285@1|root,COG5285@2|Bacteria,2GNXP@201174|Actinobacteria	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
BYD2_k127_2598257_3	1123023.JIAI01000001_gene6484	9.307e-250	797.0	COG4805@1|root,COG4805@2|Bacteria,2GMUR@201174|Actinobacteria,4DZQU@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF885)	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
BYD2_k127_2598257_17	1144319.PMI16_00602	1.632e-90	304.0	COG0580@1|root,COG0580@2|Bacteria,1MXTJ@1224|Proteobacteria,2VK6T@28216|Betaproteobacteria,473E7@75682|Oxalobacteraceae	28216|Betaproteobacteria	U	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity	aqpZ	-	-	ko:K06188	-	-	-	-	ko00000,ko02000	1.A.8	-	-	MIP
BYD2_k127_2598257_19	644283.Micau_0572	2.006e-77	276.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria,4D8GP@85008|Micromonosporales	201174|Actinobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
BYD2_k127_2598257_27	326424.FRAAL4218	1.29e-50	203.0	COG0563@1|root,COG0563@2|Bacteria,2I8TV@201174|Actinobacteria	201174|Actinobacteria	F	adenylate kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2598257_13	1120950.KB892784_gene202	7.406e-119	396.0	COG2171@1|root,COG2171@2|Bacteria,2IBDI@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the transferase hexapeptide repeat family	dapD	-	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,Hexapep_2,THDPS_N_2
BYD2_k127_2598257_29	1313172.YM304_03320	1.148e-36	141.0	COG2964@1|root,COG2964@2|Bacteria,2IHSD@201174|Actinobacteria	201174|Actinobacteria	S	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22
BYD2_k127_2598257_31	882082.SaccyDRAFT_2605	1.702e-15	84.0	COG0011@1|root,COG0011@2|Bacteria,2HS4V@201174|Actinobacteria,4ECDI@85010|Pseudonocardiales	201174|Actinobacteria	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
BYD2_k127_2598257_6	298655.KI912266_gene6563	1.413e-213	673.0	COG0402@1|root,COG0402@2|Bacteria,2GM63@201174|Actinobacteria,4ETUC@85013|Frankiales	201174|Actinobacteria	F	PFAM amidohydrolase	-	-	3.5.4.32	ko:K18456	-	-	-	-	ko00000,ko01000	-	-	-	Amidohydro_1
BYD2_k127_2598257_32	1411123.JQNH01000001_gene1763	8.609e-15	89.0	COG5653@1|root,COG5653@2|Bacteria,1N7WR@1224|Proteobacteria,2U6KY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_6
BYD2_k127_2598257_24	1160718.SU9_29346	1.715e-55	219.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_2_3,Glycos_transf_2
BYD2_k127_2598257_10	196162.Noca_1635	2.031e-131	435.0	COG0044@1|root,COG0044@2|Bacteria,2GK4A@201174|Actinobacteria,4DP6H@85009|Propionibacteriales	201174|Actinobacteria	F	Amidohydrolase family	hyuA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
BYD2_k127_2598257_20	1313172.YM304_25320	1.226e-69	246.0	COG4630@1|root,COG4630@2|Bacteria,2I33J@201174|Actinobacteria	201174|Actinobacteria	F	Xanthine dehydrogenase iron-sulfur cluster and FAD-binding subunit A	xdhA	-	1.17.1.4	ko:K13481	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5,Fer2,Fer2_2
BYD2_k127_2598257_28	526225.Gobs_3388	7.421e-50	194.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4EX6A@85013|Frankiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
BYD2_k127_2598257_2	1313172.YM304_25340	1.684e-261	830.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	pucD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
BYD2_k127_2598257_7	1313172.YM304_01600	5.819e-159	516.0	COG0624@1|root,COG0624@2|Bacteria,2GJDE@201174|Actinobacteria,4CN6K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase family M28	-	-	3.5.1.6,3.5.1.87	ko:K06016	ko00240,ko01100,map00240,map01100	M00046	R00905,R04666	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
BYD2_k127_2598257_11	335659.S23_54090	2.981e-128	419.0	COG0388@1|root,COG0388@2|Bacteria,1MXG5@1224|Proteobacteria,2TVCS@28211|Alphaproteobacteria,3JVWS@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Carbon-nitrogen hydrolase	-	-	3.5.1.77	ko:K01459	-	-	-	-	ko00000,ko01000	-	-	-	CN_hydrolase
BYD2_k127_2598257_15	266117.Rxyl_3023	4.306e-107	360.0	COG1171@1|root,COG1171@2|Bacteria,2I8ZW@201174|Actinobacteria,4CQ5T@84995|Rubrobacteria	84995|Rubrobacteria	E	Pyridoxal-phosphate dependent enzyme	-	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
BYD2_k127_2598257_1	1313172.YM304_01580	0.0	1134.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
BYD2_k127_2598257_14	1313172.YM304_01570	1.649e-118	390.0	COG0402@1|root,COG0402@2|Bacteria,2ISY0@201174|Actinobacteria	201174|Actinobacteria	F	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
BYD2_k127_2598257_9	196162.Noca_1630	1.187e-132	436.0	COG2141@1|root,COG2141@2|Bacteria,2GNQ3@201174|Actinobacteria,4DT50@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
BYD2_k127_2598257_8	35754.JNYJ01000021_gene572	4.102e-141	466.0	COG2141@1|root,COG4639@1|root,COG2141@2|Bacteria,COG4639@2|Bacteria,2GM7W@201174|Actinobacteria,4DKZI@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33,Bac_luciferase
BYD2_k127_2598257_23	479435.Kfla_5998	3.262e-58	207.0	COG0030@1|root,COG0030@2|Bacteria,2IMS8@201174|Actinobacteria,4DWR1@85009|Propionibacteriales	201174|Actinobacteria	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family	-	-	2.1.1.184	ko:K00561	-	-	R10716	RC00003,RC03257	br01600,ko00000,ko01000,ko01504,ko03009	-	-	-	RrnaAD
BYD2_k127_2598257_21	298653.Franean1_2324	2.94e-66	228.0	COG0655@1|root,COG0655@2|Bacteria,2II43@201174|Actinobacteria,4ESWD@85013|Frankiales	201174|Actinobacteria	S	Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
BYD2_k127_2598257_12	1229780.BN381_130222	1.481e-119	411.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_2598257_5	1229780.BN381_130221	1.037e-213	668.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_2598257_18	644283.Micau_4933	1.523e-82	284.0	COG1073@1|root,COG1073@2|Bacteria,2GNDJ@201174|Actinobacteria,4DMCT@85008|Micromonosporales	201174|Actinobacteria	S	alpha beta	-	-	3.1.1.101	ko:K21104	-	-	R11540	-	ko00000,ko01000	-	-	-	Abhydrolase_5,DLH,Hydrolase_4,PAF-AH_p_II
BYD2_k127_2598257_22	392499.Swit_2085	1.459e-58	211.0	2CG3W@1|root,32X0W@2|Bacteria,1NZC5@1224|Proteobacteria,2USZ5@28211|Alphaproteobacteria,2KASK@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2598257_34	1123258.AQXZ01000008_gene1315	1.201e-10	68.0	2DWDF@1|root,33ZT1@2|Bacteria,2GU9G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2598257_33	287986.DV20_10210	3.63e-13	81.0	2DWDF@1|root,33ZT1@2|Bacteria,2GU9G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2598257_25	408672.NBCG_01788	4.577e-54	204.0	COG3153@1|root,COG3153@2|Bacteria,2IKX0@201174|Actinobacteria,4DSCI@85009|Propionibacteriales	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	ko:K03824,ko:K09964	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
BYD2_k127_2598257_30	1292020.H483_0102440	2.361e-23	112.0	COG1024@1|root,COG1024@2|Bacteria,2GKJ6@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA19	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_2609656_10	298655.KI912266_gene5952	2.641e-32	127.0	COG1946@1|root,COG1946@2|Bacteria,2GZFD@201174|Actinobacteria,4EV2I@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
BYD2_k127_2609656_6	298653.Franean1_4035	1.507e-114	374.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,4EU5K@85013|Frankiales	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_2609656_2	298653.Franean1_4034	2.651e-217	680.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria,4ETXR@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_2609656_3	222534.KB893716_gene1882	2.586e-195	616.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,4EUN3@85013|Frankiales	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
BYD2_k127_2609656_5	365528.KB891226_gene1281	5.358e-127	411.0	COG1028@1|root,COG1028@2|Bacteria,2GKJD@201174|Actinobacteria	201174|Actinobacteria	IQ	Dehydrogenase reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_2609656_0	365528.KB891210_gene2148	9.988e-295	910.0	COG0183@1|root,COG1545@1|root,COG0183@2|Bacteria,COG1545@2|Bacteria,2IETY@201174|Actinobacteria,4EXA5@85013|Frankiales	201174|Actinobacteria	I	Rubredoxin-like zinc ribbon domain (DUF35_N)	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
BYD2_k127_2609656_4	1150398.JIBJ01000012_gene2117	4.664e-165	525.0	COG0604@1|root,COG0604@2|Bacteria,2GK40@201174|Actinobacteria	201174|Actinobacteria	C	NADPH quinone reductase	fadB5	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_2609656_8	365528.KB891231_gene176	4.543e-70	242.0	2A3AC@1|root,30RSD@2|Bacteria,2IKHP@201174|Actinobacteria,4EVHF@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2609656_9	388051.AUFE01000103_gene4871	2.876e-46	173.0	COG1846@1|root,COG1846@2|Bacteria,1QWDS@1224|Proteobacteria,2WH7Q@28216|Betaproteobacteria	28216|Betaproteobacteria	K	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
BYD2_k127_2609656_1	1380393.JHVP01000004_gene612	1.24e-220	702.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
BYD2_k127_2609656_7	1463858.JOHR01000014_gene5138	3.875e-80	273.0	COG4977@1|root,COG4977@2|Bacteria,2I2KX@201174|Actinobacteria	201174|Actinobacteria	K	PFAM ThiJ PfpI	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
BYD2_k127_2629801_8	537013.CLOSTMETH_02348	5.627e-14	72.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3WGCR@541000|Ruminococcaceae	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
BYD2_k127_2629801_1	1229780.BN381_330051	3.232e-107	366.0	COG0052@1|root,COG0052@2|Bacteria,2GMYC@201174|Actinobacteria,3UWBA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS2 family	rpsB	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
BYD2_k127_2629801_5	471853.Bcav_1964	3.788e-70	245.0	COG2045@1|root,COG2045@2|Bacteria,2II0K@201174|Actinobacteria	201174|Actinobacteria	H	Belongs to the ComB family	-	-	3.1.3.71	ko:K05979	ko00680,ko01120,map00680,map01120	M00358	R05789	RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	2-ph_phosp
BYD2_k127_2629801_7	1229780.BN381_330050	5.321e-24	119.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
BYD2_k127_2629801_4	235985.BBPN01000031_gene2098	1.909e-73	256.0	COG1191@1|root,COG1191@2|Bacteria,2GKBK@201174|Actinobacteria,2NE9K@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70, region 4	whiG	-	-	ko:K02405	ko02020,ko02025,ko02026,ko02040,ko05111,map02020,map02025,map02026,map02040,map05111	-	-	-	ko00000,ko00001,ko02035,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_2629801_2	1313172.YM304_27520	8.308e-82	295.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CN5T@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	ko:K03733	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
BYD2_k127_2629801_6	1313172.YM304_27530	3.82e-61	236.0	COG0758@1|root,COG0758@2|Bacteria,2GKDA@201174|Actinobacteria	201174|Actinobacteria	LU	DNA protecting protein DprA	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
BYD2_k127_2629801_0	1313172.YM304_27540	9.648e-157	515.0	COG0606@1|root,COG0606@2|Bacteria,2GJIQ@201174|Actinobacteria	201174|Actinobacteria	O	PFAM magnesium chelatase ChlI subunit	comM	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
BYD2_k127_2629801_3	1313172.YM304_18790	2.145e-76	269.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4CNAF@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
BYD2_k127_2663222_7	1313172.YM304_24990	7.512e-08	55.0	COG0287@1|root,COG0287@2|Bacteria,2GKB4@201174|Actinobacteria,4CNBS@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydrogenase	-	-	1.3.1.12	ko:K00210,ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	PDH
BYD2_k127_2663222_3	649831.L083_2002	3.481e-131	435.0	COG0128@1|root,COG0128@2|Bacteria,2GJKX@201174|Actinobacteria,4DB3A@85008|Micromonosporales	201174|Actinobacteria	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
BYD2_k127_2663222_4	1313172.YM304_20150	1.166e-61	218.0	COG0283@1|root,COG0283@2|Bacteria,2H3SI@201174|Actinobacteria,4CNDQ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Cytidylate kinase	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
BYD2_k127_2663222_5	1313172.YM304_20160	2.463e-57	209.0	COG0204@1|root,COG0204@2|Bacteria,2HG51@201174|Actinobacteria,4CN6X@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
BYD2_k127_2663222_6	1089544.KB912942_gene1790	2.863e-32	143.0	2E8WU@1|root,3336Z@2|Bacteria,2GR5V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2663222_2	1313172.YM304_25520	7.676e-151	508.0	COG0761@1|root,COG0761@2|Bacteria,2GIZ7@201174|Actinobacteria,4CMP7@84992|Acidimicrobiia	84992|Acidimicrobiia	IM	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K03527	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05884,R08210	RC01137,RC01487	ko00000,ko00001,ko00002,ko01000	-	-	-	LYTB
BYD2_k127_2663222_0	1313172.YM304_25530	4.13e-190	604.0	COG1625@1|root,COG1625@2|Bacteria,2H3RR@201174|Actinobacteria,4CMW9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Protein of unknown function (DUF512)	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
BYD2_k127_2663222_1	1229780.BN381_40072	2.048e-176	587.0	COG1160@1|root,COG1160@2|Bacteria,2GJ8J@201174|Actinobacteria,3UWEY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	Cytidylate_kin,KH_dom-like,MMR_HSR1
BYD2_k127_2693915_7	35754.JNYJ01000011_gene736	5.59e-40	159.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DH9I@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_2693915_10	35754.JNYJ01000023_gene8323	2.503e-31	123.0	2C82G@1|root,32RK9@2|Bacteria,2IRVD@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
BYD2_k127_2693915_11	1122138.AQUZ01000066_gene4373	3.928e-24	104.0	COG2823@1|root,COG2823@2|Bacteria,2IS5M@201174|Actinobacteria	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
BYD2_k127_2693915_6	1121946.AUAX01000005_gene5515	2.61e-60	224.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4DA6A@85008|Micromonosporales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_2693915_9	216594.MMAR_4436	1.796e-34	139.0	2B2M4@1|root,31V6I@2|Bacteria,2GV2T@201174|Actinobacteria,23DZT@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2693915_12	1380390.JIAT01000011_gene2429	8.16e-20	105.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	MA20_40075	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
BYD2_k127_2693915_0	1211815.CBYP010000056_gene3341	0.0	1002.0	COG2072@1|root,COG2072@2|Bacteria,2GKYU@201174|Actinobacteria,4EU3A@85013|Frankiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	pamO	GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0016999,GO:0017000,GO:0017144,GO:0018130,GO:0044237,GO:0044249,GO:0046483,GO:0055114,GO:0071704,GO:1901334,GO:1901336,GO:1901360,GO:1901362,GO:1901576	1.14.13.170,1.14.13.171,1.14.13.22	ko:K03379,ko:K18091	ko00930,ko01120,ko01130,ko01220,map00930,map01120,map01130,map01220	M00819	R02231,R06622	RC00662,RC01550	ko00000,ko00001,ko00002,ko01000	-	-	-	FMO-like,NAD_binding_8,Pyr_redox_2,Pyr_redox_3
BYD2_k127_2693915_4	1246995.AFR_27020	1.988e-98	329.0	COG0656@1|root,COG0656@2|Bacteria,2HGQC@201174|Actinobacteria,4DCC2@85008|Micromonosporales	201174|Actinobacteria	S	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
BYD2_k127_2693915_5	1229780.BN381_210023	2.659e-62	229.0	COG0662@1|root,COG0662@2|Bacteria,2IMPE@201174|Actinobacteria	201174|Actinobacteria	G	COG0662 Mannose-6-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_2693915_2	1313172.YM304_09700	2.068e-179	580.0	COG0749@1|root,COG0749@2|Bacteria,2GM8R@201174|Actinobacteria	201174|Actinobacteria	L	DNA polymerase	polA2	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_pol_A
BYD2_k127_2693915_1	1122604.JONR01000011_gene3651	3.21e-184	585.0	COG4941@1|root,COG4941@2|Bacteria,1MU3D@1224|Proteobacteria,1RN25@1236|Gammaproteobacteria,1X30Y@135614|Xanthomonadales	135614|Xanthomonadales	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_2693915_8	313589.JNB_14338	8.973e-40	152.0	COG3795@1|root,COG3795@2|Bacteria,2IHYC@201174|Actinobacteria,4FHYY@85021|Intrasporangiaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_2693915_3	1449346.JQMO01000002_gene1686	8.815e-133	428.0	COG0655@1|root,COG0655@2|Bacteria,2GKTM@201174|Actinobacteria,2M1ZC@2063|Kitasatospora	201174|Actinobacteria	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
BYD2_k127_2708061_4	106370.Francci3_2657	2.115e-65	237.0	COG2243@1|root,COG2243@2|Bacteria,2GJFA@201174|Actinobacteria,4ESHJ@85013|Frankiales	201174|Actinobacteria	H	precorrin-6A synthase (deacetylating)	cobF	-	2.1.1.152	ko:K02228	ko00860,ko01100,map00860,map01100	-	R05219	RC00003,RC00923,RC02890	ko00000,ko00001,ko01000	-	-	-	TP_methylase
BYD2_k127_2708061_0	561175.KB894102_gene1115	3.686e-194	615.0	COG0766@1|root,COG0766@2|Bacteria,2GJPW@201174|Actinobacteria,4EH9W@85012|Streptosporangiales	201174|Actinobacteria	M	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase)	-	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
BYD2_k127_2708061_5	794903.OPIT5_00825	1.863e-63	225.0	COG1896@1|root,COG1896@2|Bacteria,46V77@74201|Verrucomicrobia,3K7Z9@414999|Opitutae	414999|Opitutae	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
BYD2_k127_2708061_10	1463881.KL591003_gene5756	0.0005772	49.0	COG0517@1|root,COG1994@1|root,COG0517@2|Bacteria,COG1994@2|Bacteria,2GJBZ@201174|Actinobacteria	201174|Actinobacteria	M	Belongs to the peptidase M50B family	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	CBS,Peptidase_M50
BYD2_k127_2708061_1	378806.STAUR_0517	9.298e-148	493.0	COG0768@1|root,COG0768@2|Bacteria,1MV8C@1224|Proteobacteria,42M1S@68525|delta/epsilon subdivisions,2WJ02@28221|Deltaproteobacteria,2YU5Y@29|Myxococcales	28221|Deltaproteobacteria	M	Penicillin-binding Protein dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	MecA_N,PBP_dimer,Transpeptidase
BYD2_k127_2708061_7	68170.KL590511_gene2984	4.824e-54	192.0	COG3576@1|root,COG3576@2|Bacteria,2I46F@201174|Actinobacteria,4EDRQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_2708061_6	1237500.ANBA01000007_gene2760	3.327e-61	214.0	COG0346@1|root,COG0346@2|Bacteria,2I2S6@201174|Actinobacteria,4EJSE@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_2708061_2	591158.SSMG_01810	4.306e-122	401.0	COG2378@1|root,COG2378@2|Bacteria,2GKFU@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
BYD2_k127_2708061_8	1172179.AUKV01000027_gene7528	8.256e-49	185.0	2E4BX@1|root,32Z7H@2|Bacteria,2IM6W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
BYD2_k127_2708061_3	1463845.JOIG01000005_gene3382	2.52e-84	289.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria	201174|Actinobacteria	L	Participates in initiation and elongation during chromosome replication	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
BYD2_k127_2713645_1	1380346.JNIH01000027_gene5813	6.463e-91	304.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_2713645_2	1120934.KB894405_gene5454	6.162e-13	79.0	COG1846@1|root,COG1846@2|Bacteria,2IHYF@201174|Actinobacteria,4E75R@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
BYD2_k127_2713645_0	1229780.BN381_330110	1.13e-147	482.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,3UWAA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
BYD2_k127_2719262_2	1298863.AUEP01000011_gene586	4.092e-114	381.0	2DBCY@1|root,2Z8GH@2|Bacteria	2|Bacteria	S	PFAM Tyrosinase	-	-	1.10.3.1,1.14.18.1	ko:K00422,ko:K00505	ko00350,ko00950,ko00965,ko01100,ko01110,ko04916,map00350,map00950,map00965,map01100,map01110,map04916	M00042	R00031,R00045,R00731,R02078,R02363,R02383,R04693,R04884	RC00046,RC00150,RC00180	ko00000,ko00001,ko00002,ko01000	-	-	-	PPO1_DWL,PPO1_KFDV,Tyrosinase
BYD2_k127_2719262_8	1041159.AZUW01000063_gene411	1.237e-45	191.0	COG2333@1|root,COG2333@2|Bacteria,1RE10@1224|Proteobacteria,2U7SC@28211|Alphaproteobacteria,4BI87@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	competence protein COMEC	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
BYD2_k127_2719262_1	936136.ARRT01000007_gene1059	1.176e-153	512.0	COG1404@1|root,COG1404@2|Bacteria,1PSEZ@1224|Proteobacteria,2V4M5@28211|Alphaproteobacteria,4BFDK@82115|Rhizobiaceae	28211|Alphaproteobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
BYD2_k127_2719262_7	1246995.AFR_08500	4.211e-52	188.0	COG2453@1|root,COG2453@2|Bacteria,2IHXA@201174|Actinobacteria,4DE5E@85008|Micromonosporales	201174|Actinobacteria	T	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase
BYD2_k127_2719262_6	1122939.ATUD01000008_gene2505	7.597e-76	267.0	COG3861@1|root,COG3861@2|Bacteria,2II0U@201174|Actinobacteria,4CPJ3@84995|Rubrobacteria	84995|Rubrobacteria	S	Domain of unknown function (DUF2382)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2382,PRC
BYD2_k127_2719262_5	928724.SacglDRAFT_00135	1.907e-91	325.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4DX43@85010|Pseudonocardiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11	ko:K07304	-	-	-	-	ko00000,ko01000	-	-	-	PMSR
BYD2_k127_2719262_10	1380354.JIAN01000008_gene3290	1.466e-34	150.0	COG1716@1|root,COG1716@2|Bacteria,2GSQ0@201174|Actinobacteria	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2719262_12	469383.Cwoe_2612	2.775e-13	80.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,4CSB9@84995|Rubrobacteria	84995|Rubrobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
BYD2_k127_2719262_11	479433.Caci_8160	4.108e-33	142.0	COG1414@1|root,COG1414@2|Bacteria,2GP02@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR
BYD2_k127_2719262_0	595593.JREV01000042_gene3975	3.691e-226	716.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,1W8T9@1268|Micrococcaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	caiA	-	1.3.8.13	ko:K08297,ko:K20035	ko00920,map00920	-	R11130	RC03363	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_2719262_4	1157637.KB892090_gene6163	1.599e-95	320.0	COG1680@1|root,COG1680@2|Bacteria,2GNVX@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	bla	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_2719262_9	1380390.JIAT01000009_gene927	7.876e-36	153.0	COG2114@1|root,COG2114@2|Bacteria,2ICJJ@201174|Actinobacteria,4CQDR@84995|Rubrobacteria	84995|Rubrobacteria	T	Adenylate and Guanylate cyclase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
BYD2_k127_2719262_3	1229780.BN381_80340	2.019e-96	324.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
BYD2_k127_2743844_4	512565.AMIS_49100	6.513e-76	271.0	COG1674@1|root,COG1716@1|root,COG1674@2|Bacteria,COG1716@2|Bacteria,2GJBR@201174|Actinobacteria	201174|Actinobacteria	D	DNA segregation ATPase FtsK SpoIIIE and related	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FHA,FtsK_SpoIIIE,Yop-YscD_cpl
BYD2_k127_2743844_0	1229780.BN381_130375	0.0	1028.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,3UX5E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	drug exporters of the RND superfamily	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	CarboxypepD_reg,MMPL
BYD2_k127_2743844_8	1122603.ATVI01000012_gene1096	1.576e-24	113.0	COG0454@1|root,COG0456@2|Bacteria,1QZJR@1224|Proteobacteria,1S8SA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_2743844_1	1242864.D187_001549	1.898e-197	639.0	COG1022@1|root,COG1022@2|Bacteria,1MU4D@1224|Proteobacteria,42N2G@68525|delta/epsilon subdivisions,2WIXB@28221|Deltaproteobacteria	28221|Deltaproteobacteria	I	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
BYD2_k127_2743844_11	1449346.JQMO01000003_gene2419	8.26e-10	72.0	2DGCV@1|root,2ZVG4@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3068)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3068
BYD2_k127_2743844_5	1254432.SCE1572_15625	1.398e-62	240.0	COG3591@1|root,COG3591@2|Bacteria	2|Bacteria	E	Belongs to the peptidase S1B family	ydgD	-	-	ko:K04775	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Trypsin,Trypsin_2
BYD2_k127_2743844_9	621372.ACIH01000160_gene3419	1.339e-21	111.0	COG0584@1|root,COG0584@2|Bacteria,1V6FX@1239|Firmicutes,4HWQD@91061|Bacilli,26TWI@186822|Paenibacillaceae	91061|Bacilli	C	glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
BYD2_k127_2743844_7	1121946.AUAX01000004_gene690	1.106e-25	112.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4DDTW@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_2743844_10	1157637.KB892100_gene2376	3.687e-21	97.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_2743844_2	2002.JOEQ01000004_gene2663	4.382e-180	597.0	COG0577@1|root,COG0577@2|Bacteria,2HW2M@201174|Actinobacteria	201174|Actinobacteria	V	efflux transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
BYD2_k127_2743844_3	35754.JNYJ01000061_gene2384	1.887e-81	301.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria,4DBDJ@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_2743844_6	1229780.BN381_170028	3e-29	130.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
BYD2_k127_2806683_4	298655.KI912266_gene5537	1.437e-125	413.0	COG2141@1|root,COG2141@2|Bacteria,2GKP1@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2806683_2	1229780.BN381_310021	1.688e-176	586.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,3UXSB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_2806683_3	1229780.BN381_310013	1.126e-135	437.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_2806683_11	1313172.YM304_11920	1.618e-72	254.0	COG0500@1|root,COG2226@2|Bacteria,2HFKS@201174|Actinobacteria,4CNX7@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2806683_15	1032480.MLP_45100	2.989e-28	134.0	COG3583@1|root,COG3583@2|Bacteria,2H4RU@201174|Actinobacteria,4DMZZ@85009|Propionibacteriales	201174|Actinobacteria	M	G5	rlpA	-	-	ko:K21688	-	-	-	-	ko00000	-	-	-	DUF348,G5,Transglycosylas
BYD2_k127_2806683_0	1449353.JQMQ01000005_gene5516	4.976e-195	616.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,2NGFF@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
BYD2_k127_2806683_20	1297742.A176_03974	0.0002521	51.0	COG0417@1|root,COG0417@2|Bacteria,1MVY9@1224|Proteobacteria,42Q4K@68525|delta/epsilon subdivisions,2WKQ1@28221|Deltaproteobacteria,2YY3U@29|Myxococcales	28221|Deltaproteobacteria	L	DNA polymerase type-B family	polB	-	2.7.7.7	ko:K02336	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol_B,DNA_pol_B_exo1,RNase_H_2
BYD2_k127_2806683_14	227882.SAV_322	1.476e-47	179.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria	201174|Actinobacteria	S	protein hemolysin III	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
BYD2_k127_2806683_17	1157640.AQWO01000006_gene2432	8.128e-15	87.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria	201174|Actinobacteria	S	protein hemolysin III	hlyIII	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
BYD2_k127_2806683_5	1313172.YM304_29160	9.713e-113	384.0	COG1126@1|root,COG1126@2|Bacteria,2GIZW@201174|Actinobacteria,4CP57@84992|Acidimicrobiia	201174|Actinobacteria	E	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	3.6.3.21	ko:K02028,ko:K09972,ko:K10041	ko02010,map02010	M00228,M00232,M00236	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.3,3.A.1.3.17,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	ABC_tran
BYD2_k127_2806683_10	1128421.JAGA01000002_gene1954	1.206e-73	276.0	COG0765@1|root,COG0765@2|Bacteria	2|Bacteria	P	amino acid transport	-	-	-	ko:K02029,ko:K09971	ko02010,map02010	M00232,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
BYD2_k127_2806683_8	1313172.YM304_29140	1.317e-80	282.0	COG4597@1|root,COG4597@2|Bacteria	2|Bacteria	P	amino acid transport	bgtB	-	-	ko:K09970,ko:K09971	ko02010,map02010	M00232	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3.18,3.A.1.3.7,3.A.1.3.8	-	-	BPD_transp_1
BYD2_k127_2806683_7	1081644.IMCC13023_09910	8.414e-112	375.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4FQH8@85023|Microbacteriaceae	201174|Actinobacteria	ET	Bacterial periplasmic substrate-binding proteins	glnH	-	-	ko:K02030,ko:K10005	ko02010,map02010	M00233,M00236	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.3,3.A.1.3.9	-	-	SBP_bac_3
BYD2_k127_2806683_1	1435356.Y013_21880	4.134e-185	589.0	COG1875@1|root,COG1875@2|Bacteria,2GK8U@201174|Actinobacteria,4FUV0@85025|Nocardiaceae	201174|Actinobacteria	T	PIN domain	phoH2	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
BYD2_k127_2806683_18	1304883.KI912532_gene215	8.422e-14	86.0	COG1556@1|root,COG1556@2|Bacteria,1R4TE@1224|Proteobacteria,2VJCF@28216|Betaproteobacteria,2KWJC@206389|Rhodocyclales	206389|Rhodocyclales	S	LUD domain	-	-	-	ko:K00782	-	-	-	-	ko00000	-	-	-	LUD_dom
BYD2_k127_2806683_6	1033738.CAEP01000028_gene1695	1.044e-112	390.0	COG1139@1|root,COG1139@2|Bacteria,1TREQ@1239|Firmicutes,4H9UI@91061|Bacilli,26EMF@186818|Planococcaceae	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate	lutB	-	-	ko:K18929	-	-	-	-	ko00000	-	-	-	DUF3390,Fer4_8,LUD_dom
BYD2_k127_2806683_13	1048834.TC41_0687	1.8e-48	183.0	COG0247@1|root,COG0247@2|Bacteria,1TPFC@1239|Firmicutes,4HAKC@91061|Bacilli	91061|Bacilli	C	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source	lutA	-	-	ko:K18928	-	-	-	-	ko00000	-	-	-	CCG
BYD2_k127_2806683_12	68260.JOAY01000003_gene4553	1.811e-55	211.0	COG0537@1|root,COG0537@2|Bacteria,2IHPT@201174|Actinobacteria	201174|Actinobacteria	FG	Histidine triad (Hit) protein	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
BYD2_k127_2806683_9	298655.KI912266_gene6056	1.431e-80	273.0	COG3467@1|root,COG3467@2|Bacteria,2IHW4@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_2806683_16	1394178.AWOO02000056_gene797	2.845e-20	92.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_2843433_4	1394178.AWOO02000056_gene797	4.788e-136	439.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_2843433_28	2074.JNYD01000004_gene4921	6.318e-22	100.0	2E3KN@1|root,32YIY@2|Bacteria,2GQXH@201174|Actinobacteria,4E6WI@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2630)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2630
BYD2_k127_2843433_30	1112204.GPOL_c00110	1.013e-19	96.0	2DSC0@1|root,33FF9@2|Bacteria,2HB1X@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2843433_31	1237149.C900_00978	3.495e-19	94.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	arsR	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
BYD2_k127_2843433_29	1171373.PACID_26860	1.413e-20	101.0	2DPEX@1|root,331T0@2|Bacteria,2IR24@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4440)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440
BYD2_k127_2843433_18	1163407.UU7_07408	3.412e-60	213.0	COG0346@1|root,COG0346@2|Bacteria,1RE6F@1224|Proteobacteria,1SP6R@1236|Gammaproteobacteria,1X75F@135614|Xanthomonadales	135614|Xanthomonadales	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_2843433_16	1121019.AUMN01000019_gene3858	1.968e-64	224.0	COG2230@1|root,COG2230@2|Bacteria,2IHZD@201174|Actinobacteria	201174|Actinobacteria	M	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
BYD2_k127_2843433_19	235985.BBPN01000012_gene6900	1.066e-59	216.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
BYD2_k127_2843433_20	1210045.ALNP01000007_gene46	4.412e-53	204.0	COG1678@1|root,COG1678@2|Bacteria,2GNRA@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the UPF0301 (AlgH) family	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K07735	-	-	-	-	ko00000,ko03000	-	-	-	DUF179
BYD2_k127_2843433_15	1313172.YM304_14930	4.571e-82	293.0	COG2120@1|root,COG2120@2|Bacteria,2IR6Y@201174|Actinobacteria,4CN50@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
BYD2_k127_2843433_23	1229780.BN381_80155	6.724e-46	175.0	COG1920@1|root,COG1920@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	cofC	GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568	2.7.7.68	ko:K14941	ko00680,ko01120,map00680,map01120	M00378	R09397	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CofC,NTP_transf_3
BYD2_k127_2843433_7	1313172.YM304_14950	3.053e-125	410.0	COG0240@1|root,COG0240@2|Bacteria,2GJSD@201174|Actinobacteria	201174|Actinobacteria	I	Glycerol-3-phosphate dehydrogenase	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
BYD2_k127_2843433_5	1260251.SPISAL_08000	2.479e-134	458.0	COG3387@1|root,COG3387@2|Bacteria,1RDWY@1224|Proteobacteria,1T141@1236|Gammaproteobacteria,1X17G@135613|Chromatiales	135613|Chromatiales	G	PFAM Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2843433_22	208444.JNYY01000033_gene5849	5.158e-48	197.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,4E1TB@85010|Pseudonocardiales	201174|Actinobacteria	T	Adenylate cyclase regulatory domain	cya	-	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
BYD2_k127_2843433_2	211114.JOEF01000016_gene3623	1.018e-168	562.0	COG0383@1|root,COG0383@2|Bacteria,2GM02@201174|Actinobacteria,4EAFE@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycosyl hydrolases family 38 N-terminal domain	-	-	3.2.1.170,3.2.1.24	ko:K01191,ko:K15524	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
BYD2_k127_2843433_10	298655.KI912266_gene5570	4.573e-118	387.0	COG1878@1|root,COG1878@2|Bacteria,2GJ59@201174|Actinobacteria,4EVXM@85013|Frankiales	201174|Actinobacteria	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
BYD2_k127_2843433_12	1155718.KB891885_gene6322	1.023e-95	325.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2843433_14	926550.CLDAP_19060	2.789e-85	306.0	COG2326@1|root,COG2326@2|Bacteria,2G5UP@200795|Chloroflexi	200795|Chloroflexi	S	Polyphosphate kinase 2 (PPK2)	-	-	-	-	-	-	-	-	-	-	-	-	PPK2
BYD2_k127_2843433_3	1123320.KB889562_gene6799	2.337e-144	465.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_2843433_21	1160137.KB907308_gene6845	5.28e-53	199.0	COG0698@1|root,COG0698@2|Bacteria,2IIDQ@201174|Actinobacteria,4G1FU@85025|Nocardiaceae	201174|Actinobacteria	G	Ribose/Galactose Isomerase	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
BYD2_k127_2843433_13	1313172.YM304_14970	5.95e-86	299.0	COG0164@1|root,COG0164@2|Bacteria,2GJFN@201174|Actinobacteria,4CN9Z@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
BYD2_k127_2843433_17	1068980.ARVW01000001_gene8075	2.098e-62	242.0	COG1834@1|root,COG1834@2|Bacteria,2GNTN@201174|Actinobacteria,4DYJJ@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM amidinotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Amidinotransf
BYD2_k127_2843433_8	477641.MODMU_3515	1.436e-124	413.0	COG1915@1|root,COG1915@2|Bacteria,2GMEZ@201174|Actinobacteria,4EUTP@85013|Frankiales	201174|Actinobacteria	S	PFAM LOR SDH bifunctional	-	-	-	-	-	-	-	-	-	-	-	-	Saccharop_dh_N
BYD2_k127_2843433_26	1313172.YM304_29470	3.336e-24	108.0	2C1D9@1|root,2ZD16@2|Bacteria,2HBJG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2843433_6	446469.Sked_08360	8.15e-128	423.0	COG0334@1|root,COG0334@2|Bacteria,2GKXG@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3	ko:K00261	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
BYD2_k127_2843433_27	1352941.M877_27240	9.821e-24	117.0	2DEAM@1|root,32U30@2|Bacteria,2IQPT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2843433_1	1169161.KB897715_gene5611	7.192e-235	744.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
BYD2_k127_2843433_24	1120950.KB892773_gene1079	6.911e-42	168.0	COG4544@1|root,COG4544@2|Bacteria,2IIXE@201174|Actinobacteria,4DR5F@85009|Propionibacteriales	201174|Actinobacteria	S	Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division	-	GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2843433_9	1229780.BN381_80180	2.316e-120	413.0	COG0389@1|root,COG0389@2|Bacteria,2GMZ3@201174|Actinobacteria,3UWGC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	impB/mucB/samB family	dinB_2	-	-	ko:K14161	-	-	-	-	ko00000,ko03400	-	-	-	IMS
BYD2_k127_2843433_11	1229780.BN381_50094	1.233e-96	355.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,3UW6V@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Pyruvate kinase, barrel domain	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
BYD2_k127_2843433_25	1156844.KB891820_gene290	4.911e-35	155.0	COG1695@1|root,COG1695@2|Bacteria,2GNEN@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_2843433_0	1464048.JNZS01000014_gene3101	0.0	1157.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4D8EW@85008|Micromonosporales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
BYD2_k127_2860495_0	84531.JMTZ01000052_gene1601	1.695e-15	87.0	COG1222@1|root,COG1222@2|Bacteria,1QVRV@1224|Proteobacteria,1SJQT@1236|Gammaproteobacteria,1X9QK@135614|Xanthomonadales	135614|Xanthomonadales	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
BYD2_k127_2860495_1	1120948.KB903224_gene336	1.828e-08	66.0	COG4251@1|root,COG5263@1|root,COG4251@2|Bacteria,COG5263@2|Bacteria,2GK6E@201174|Actinobacteria,4DX42@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_2883243_3	1120950.KB892752_gene6177	1.958e-17	88.0	COG0640@1|root,COG0640@2|Bacteria,2I4A4@201174|Actinobacteria,4DS2M@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BYD2_k127_2883243_1	525909.Afer_1754	1.721e-43	164.0	COG0691@1|root,COG0691@2|Bacteria,2GJX1@201174|Actinobacteria,4CN4T@84992|Acidimicrobiia	84992|Acidimicrobiia	J	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
BYD2_k127_2883243_2	1313172.YM304_27760	2.887e-34	138.0	COG1310@1|root,COG1310@2|Bacteria,2HG96@201174|Actinobacteria,4CN7H@84992|Acidimicrobiia	84992|Acidimicrobiia	S	JAB/MPN domain	-	-	3.13.1.6	ko:K21140	ko04122,map04122	-	R11524	RC00064,RC00090	ko00000,ko00001,ko01000	-	-	-	Prok-JAB
BYD2_k127_2883243_0	1229780.BN381_80117	4.73e-117	382.0	COG0031@1|root,COG0031@2|Bacteria,2GIXE@201174|Actinobacteria,3UX63@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Pyridoxal-phosphate dependent enzyme	cysM	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.5.1.113	ko:K21148	ko04122,map04122	-	R10610	RC03225	ko00000,ko00001,ko01000	-	-	-	PALP
BYD2_k127_2887359_0	561175.KB894094_gene1898	1.046e-221	696.0	COG0065@1|root,COG0065@2|Bacteria,2GKT7@201174|Actinobacteria,4EFIU@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	4.2.1.33,4.2.1.35	ko:K01703	ko00290,ko00660,ko00966,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map00966,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase
BYD2_k127_2887359_1	1313172.YM304_12870	3.465e-55	201.0	COG1414@1|root,COG1414@2|Bacteria,2HGKQ@201174|Actinobacteria,4CP2Q@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix isocitrate lyase regulation	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
BYD2_k127_2888053_4	710111.FraQA3DRAFT_5703	3.742e-54	196.0	COG0366@1|root,COG0366@2|Bacteria,2GIV1@201174|Actinobacteria,4EREC@85013|Frankiales	201174|Actinobacteria	G	Trehalose synthase	treS	GO:0000023,GO:0000271,GO:0003674,GO:0003824,GO:0004553,GO:0004556,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005984,GO:0005991,GO:0005992,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009311,GO:0009312,GO:0009987,GO:0015980,GO:0016020,GO:0016051,GO:0016160,GO:0016161,GO:0016787,GO:0016798,GO:0016853,GO:0016866,GO:0033692,GO:0034637,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046872,GO:0047471,GO:0055114,GO:0071704,GO:0071944,GO:1901576	3.2.1.1,5.4.99.16	ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R02108,R02112,R11262	RC01816	ko00000,ko00001,ko01000	-	GH13	iNJ661.Rv0126	Alpha-amylase,Malt_amylase_C
BYD2_k127_2888053_0	235985.BBPN01000009_gene3843	2.504e-288	904.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,2NJXT@228398|Streptacidiphilus	201174|Actinobacteria	P	Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
BYD2_k127_2888053_3	247156.NFA_28310	7.367e-84	287.0	COG0426@1|root,COG0426@2|Bacteria,2GKJ9@201174|Actinobacteria,4FV5C@85025|Nocardiaceae	201174|Actinobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2888053_2	526225.Gobs_2405	8.522e-156	533.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2ICMZ@201174|Actinobacteria,4EX4U@85013|Frankiales	201174|Actinobacteria	K	PFAM transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
BYD2_k127_2888053_1	463191.SSEG_08420	1.796e-211	674.0	COG0366@1|root,COG0366@2|Bacteria,2GJKR@201174|Actinobacteria	201174|Actinobacteria	G	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB	glgE	-	2.4.99.16	ko:K16147	ko00500,ko01100,map00500,map01100	-	R09994	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3416
BYD2_k127_2916496_2	1121377.KB906400_gene1245	7.244e-05	48.0	COG0554@1|root,COG0554@2|Bacteria,1WI6Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
BYD2_k127_2916496_1	1313172.YM304_19200	4.386e-40	161.0	COG0317@1|root,COG0317@2|Bacteria	2|Bacteria	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	sdaAB	-	2.7.6.5,3.1.7.2,4.3.1.17,4.3.1.19	ko:K01139,ko:K01752,ko:K01754	ko00230,ko00260,ko00270,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00230,map00260,map00270,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00336,R00429,R00590,R00996	RC00002,RC00078,RC00331,RC00418,RC02600	ko00000,ko00001,ko00002,ko01000,ko03009	-	-	-	ACT,HD_4,PALP,RelA_SpoT,SDH_beta
BYD2_k127_2916496_0	1156844.KB891813_gene6686	2.775e-85	322.0	COG0642@1|root,COG2205@2|Bacteria,2I2WT@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_2935399_5	929712.KI912613_gene1212	2.399e-21	109.0	COG0515@1|root,COG0515@2|Bacteria,2HMAN@201174|Actinobacteria	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
BYD2_k127_2935399_6	561175.KB894093_gene2688	3.731e-06	56.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
BYD2_k127_2935399_3	1120797.KB908263_gene164	1.202e-29	138.0	COG1520@1|root,COG1520@2|Bacteria,2IBDZ@201174|Actinobacteria,236PD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,zinc_ribbon_2
BYD2_k127_2935399_4	1184609.KILIM_004_00210	7.605e-23	111.0	2DR8X@1|root,33AQM@2|Bacteria,2GXTC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2935399_2	1184609.KILIM_004_00220	1.077e-35	145.0	COG4113@1|root,COG4113@2|Bacteria	2|Bacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
BYD2_k127_2935399_0	1123253.AUBD01000005_gene242	2.315e-70	254.0	COG0189@1|root,COG0189@2|Bacteria,1MV29@1224|Proteobacteria,1SB70@1236|Gammaproteobacteria,1X81A@135614|Xanthomonadales	135614|Xanthomonadales	HJ	COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase)	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2935399_1	935839.JAGJ01000008_gene1750	6.76e-58	205.0	COG3865@1|root,COG3865@2|Bacteria,2IHTH@201174|Actinobacteria,4F4NZ@85017|Promicromonosporaceae	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	3-dmu-9_3-mt
BYD2_k127_2956608_5	525904.Tter_1698	1.041e-136	439.0	COG0719@1|root,COG0719@2|Bacteria,2NNKT@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufB	sufB	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360	-	ko:K07033,ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
BYD2_k127_2956608_26	66377.JOBH01000006_gene238	2.939e-40	158.0	COG1309@1|root,COG1309@2|Bacteria,2GWAE@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2956608_1	1211815.CBYP010000067_gene124	2.114e-216	685.0	COG0747@1|root,COG0747@2|Bacteria,2ID29@201174|Actinobacteria,4EX5B@85013|Frankiales	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
BYD2_k127_2956608_8	1211815.CBYP010000067_gene121	7.217e-134	435.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,4EU1K@85013|Frankiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
BYD2_k127_2956608_13	1146883.BLASA_2835	7.199e-94	318.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,4EX5A@85013|Frankiales	201174|Actinobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
BYD2_k127_2956608_7	1211815.CBYP010000067_gene119	5.305e-134	451.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
BYD2_k127_2956608_6	1211815.CBYP010000067_gene118	1.122e-134	453.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EU6B@85013|Frankiales	201174|Actinobacteria	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
BYD2_k127_2956608_11	1254432.SCE1572_01045	2.409e-98	343.0	COG1222@1|root,COG1222@2|Bacteria,1R4U1@1224|Proteobacteria	1224|Proteobacteria	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA,ClpS
BYD2_k127_2956608_25	1206737.BAGF01000060_gene3979	5.863e-44	164.0	COG5470@1|root,COG5470@2|Bacteria,2IQ47@201174|Actinobacteria,4G20Z@85025|Nocardiaceae	201174|Actinobacteria	S	Domain of unknown function (DUF1330)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
BYD2_k127_2956608_3	1313172.YM304_29200	4.22e-197	632.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CNI7@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_2956608_2	1313172.YM304_29210	3.981e-208	664.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CNI7@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_2956608_27	525904.Tter_0358	9.352e-29	127.0	COG3266@1|root,COG4719@1|root,COG3266@2|Bacteria,COG4719@2|Bacteria	2|Bacteria	GM	domain, Protein	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	DUF11,Pkinase
BYD2_k127_2956608_16	66875.JODY01000019_gene330	2.707e-87	303.0	COG2141@1|root,COG2141@2|Bacteria,2GJTP@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2956608_29	105422.BBPM01000007_gene6433	1.439e-19	93.0	2E37T@1|root,32Y7G@2|Bacteria,2GQH5@201174|Actinobacteria,2NJ15@228398|Streptacidiphilus	201174|Actinobacteria	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
BYD2_k127_2956608_28	644283.Micau_0783	9.748e-24	109.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,4DDA7@85008|Micromonosporales	201174|Actinobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	-
BYD2_k127_2956608_19	526227.Mesil_1866	9.561e-66	238.0	COG1611@1|root,COG1611@2|Bacteria	2|Bacteria	S	cytokinin biosynthetic process	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
BYD2_k127_2956608_20	479433.Caci_1632	2.752e-59	209.0	COG0663@1|root,COG0663@2|Bacteria,2GP22@201174|Actinobacteria	201174|Actinobacteria	K	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily	gca	-	-	ko:K02617	-	-	-	-	ko00000	-	-	-	Hexapep
BYD2_k127_2956608_23	13689.BV96_02051	2.909e-55	198.0	COG1853@1|root,COG1853@2|Bacteria,1RGYM@1224|Proteobacteria,2UCHI@28211|Alphaproteobacteria,2K4VD@204457|Sphingomonadales	204457|Sphingomonadales	K	DIM6 NTAB family	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
BYD2_k127_2956608_14	1313172.YM304_14700	1.337e-89	305.0	COG1235@1|root,COG1235@2|Bacteria,2IJCH@201174|Actinobacteria	201174|Actinobacteria	S	Beta-lactamase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
BYD2_k127_2956608_9	471852.Tcur_1579	1.174e-102	342.0	COG0596@1|root,COG0596@2|Bacteria,2HMX1@201174|Actinobacteria,4EHZ7@85012|Streptosporangiales	201174|Actinobacteria	S	Alpha/beta hydrolase family	ephC	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_2956608_15	1313172.YM304_14260	3.354e-89	308.0	COG1194@1|root,COG1194@2|Bacteria,2GJD9@201174|Actinobacteria,4CNWS@84992|Acidimicrobiia	84992|Acidimicrobiia	L	endonuclease III	-	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD
BYD2_k127_2956608_22	1192034.CAP_8545	1.54e-55	205.0	COG0500@1|root,COG2226@2|Bacteria,1R51W@1224|Proteobacteria,43AS2@68525|delta/epsilon subdivisions,2X666@28221|Deltaproteobacteria,2Z27D@29|Myxococcales	28221|Deltaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_2956608_17	1313172.YM304_14250	7.435e-76	263.0	COG2030@1|root,COG2030@2|Bacteria,2GN4R@201174|Actinobacteria,4CMYB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
BYD2_k127_2956608_31	1906.SFRA_02465	0.0003016	53.0	2DPU0@1|root,333DA@2|Bacteria,2IARZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2956608_0	1229780.BN381_210057	3.903e-235	745.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.1,1.3.8.12	ko:K00248,ko:K14448	ko00071,ko00280,ko00630,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00630,map00650,map01100,map01110,map01120,map01200,map01212	M00373	R01175,R01178,R02661,R03172,R04751,R09293	RC00052,RC00068,RC00076,RC00120,RC00148,RC02483	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_2956608_12	882086.SacxiDRAFT_0956	2.003e-96	331.0	COG2120@1|root,COG2120@2|Bacteria,2GMVD@201174|Actinobacteria,4DZM2@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
BYD2_k127_2956608_21	685727.REQ_13980	3.577e-57	203.0	2F5RB@1|root,33YA7@2|Bacteria,2GMGC@201174|Actinobacteria,4G0Y7@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2,SnoaL_4
BYD2_k127_2956608_18	1229780.BN381_10204	3.698e-68	242.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,3UXFS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_2956608_24	1382356.JQMP01000003_gene1667	1.211e-45	178.0	COG2141@1|root,COG2141@2|Bacteria,2GB9A@200795|Chloroflexi,27Y8J@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_2956608_10	1120949.KB903315_gene252	1.958e-102	347.0	COG0654@1|root,COG0654@2|Bacteria,2GJG5@201174|Actinobacteria,4DII5@85008|Micromonosporales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
BYD2_k127_2956608_4	1146883.BLASA_3314	1.304e-180	576.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4EVDD@85013|Frankiales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
BYD2_k127_2956608_30	345341.KUTG_00776	2.566e-15	77.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,4E1G7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BYD2_k127_2959172_14	211114.JOEF01000004_gene6501	1.565e-73	250.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,2GNNG@201174|Actinobacteria,4E244@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	yjgM	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
BYD2_k127_2959172_10	479431.Namu_1999	4.4e-99	338.0	COG1073@1|root,COG1073@2|Bacteria,2IPVI@201174|Actinobacteria	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2959172_4	1394178.AWOO02000014_gene7681	4.226e-203	647.0	COG2124@1|root,COG2124@2|Bacteria,2HMMY@201174|Actinobacteria,4ENAU@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_2959172_29	1038867.AXAY01000001_gene6250	5.525e-18	94.0	COG1141@1|root,COG1141@2|Bacteria,1MZJU@1224|Proteobacteria,2UCKK@28211|Alphaproteobacteria,3K07G@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	4Fe-4S single cluster domain of Ferredoxin I	MA20_16570	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_15
BYD2_k127_2959172_20	1394178.AWOO02000014_gene7679	2.347e-53	195.0	COG1309@1|root,COG1309@2|Bacteria,2GUIR@201174|Actinobacteria,4EM84@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2959172_5	2754.EH55_03185	3.595e-151	510.0	COG0474@1|root,COG0474@2|Bacteria,3TBY8@508458|Synergistetes	508458|Synergistetes	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
BYD2_k127_2959172_11	196162.Noca_0968	5.185e-89	303.0	COG1136@1|root,COG1136@2|Bacteria,2GJQV@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_2959172_2	196162.Noca_0969	6.269e-211	683.0	COG0577@1|root,COG0577@2|Bacteria	2|Bacteria	V	efflux transmembrane transporter activity	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_2959172_15	1386089.N865_15090	1.938e-72	249.0	COG1765@1|root,COG1765@2|Bacteria,2IG8A@201174|Actinobacteria,4FJTH@85021|Intrasporangiaceae	201174|Actinobacteria	O	redox protein regulator of disulfide bond formation	-	-	-	-	-	-	-	-	-	-	-	-	OsmC
BYD2_k127_2959172_19	1298863.AUEP01000011_gene622	4.519e-56	209.0	COG2120@1|root,COG2120@2|Bacteria,2IJD0@201174|Actinobacteria	201174|Actinobacteria	S	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
BYD2_k127_2959172_30	1043493.BBLU01000015_gene1145	9.006e-16	90.0	COG1309@1|root,COG1309@2|Bacteria,2IHGM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_2959172_12	1121019.AUMN01000002_gene145	1.065e-84	291.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_2959172_1	35754.JNYJ01000020_gene289	3.952e-236	750.0	COG2267@1|root,COG4671@1|root,COG2267@2|Bacteria,COG4671@2|Bacteria,2HU5Q@201174|Actinobacteria,4DBMT@85008|Micromonosporales	201174|Actinobacteria	I	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Glyco_tran_28_C
BYD2_k127_2959172_13	37919.EP51_08760	1.053e-77	268.0	COG1028@1|root,COG1028@2|Bacteria,2GM6W@201174|Actinobacteria,4FZ74@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_2959172_9	1211815.CBYP010000069_gene1395	7.206e-102	337.0	COG1028@1|root,COG1028@2|Bacteria,2I95F@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K14633	ko01057,ko01130,map01057,map01130	-	R09309,R09310	RC02484	ko00000,ko00001,ko01000	-	-	-	adh_short,adh_short_C2
BYD2_k127_2959172_22	1229780.BN381_130095	1.314e-51	210.0	COG0346@1|root,COG0346@2|Bacteria,2IFUM@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	cadI	GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_2959172_17	1394178.AWOO02000023_gene5476	9.17e-60	212.0	COG2606@1|root,COG2606@2|Bacteria,2GKUX@201174|Actinobacteria,4EJAQ@85012|Streptosporangiales	201174|Actinobacteria	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
BYD2_k127_2959172_23	1313172.YM304_16750	4.91e-41	158.0	COG3467@1|root,COG3467@2|Bacteria,2IK9H@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_2959172_8	1464048.JNZS01000028_gene1716	7.397e-131	424.0	COG2207@1|root,COG2207@2|Bacteria,2GK7Q@201174|Actinobacteria,4DCA4@85008|Micromonosporales	201174|Actinobacteria	K	Cupin	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_6,HTH_18
BYD2_k127_2959172_27	1125971.ASJB01000055_gene6801	1.421e-26	123.0	COG1359@1|root,COG1359@2|Bacteria,2IM32@201174|Actinobacteria,4EBNC@85010|Pseudonocardiales	201174|Actinobacteria	S	NIPSNAP	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
BYD2_k127_2959172_3	1089546.AQUI01000002_gene3138	2.153e-205	649.0	COG0491@1|root,COG0607@1|root,COG0491@2|Bacteria,COG0607@2|Bacteria,2GN50@201174|Actinobacteria,40A50@622450|Actinopolysporales	201174|Actinobacteria	P	Rhodanese Homology Domain	blh	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
BYD2_k127_2959172_7	479434.Sthe_0078	6.022e-138	455.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_2959172_25	543632.JOJL01000027_gene2731	2.886e-38	157.0	COG1846@1|root,COG1846@2|Bacteria,2HV1B@201174|Actinobacteria,4DGHE@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BYD2_k127_2959172_16	1003195.SCAT_0388	1.63e-67	235.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
BYD2_k127_2959172_6	243231.GSU1203	3.214e-150	491.0	COG3263@1|root,COG3263@2|Bacteria,1MVKV@1224|Proteobacteria,42MWU@68525|delta/epsilon subdivisions,2WKCW@28221|Deltaproteobacteria	28221|Deltaproteobacteria	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
BYD2_k127_2959172_21	211114.JOEF01000016_gene3571	2.784e-52	192.0	COG1510@1|root,COG1510@2|Bacteria,2GNYV@201174|Actinobacteria,4E4M4@85010|Pseudonocardiales	201174|Actinobacteria	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BYD2_k127_2959172_26	365528.KB891286_gene5809	1.603e-28	136.0	COG5500@1|root,COG5500@2|Bacteria,2HU1F@201174|Actinobacteria,4EWCH@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF1772)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1772
BYD2_k127_2959172_28	1110697.NCAST_20_05570	2.82e-22	98.0	COG2608@1|root,COG2608@2|Bacteria,2GQK5@201174|Actinobacteria,4G3TS@85025|Nocardiaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	copZ	-	-	ko:K07213	ko04978,map04978	-	-	-	ko00000,ko00001	-	-	-	HMA
BYD2_k127_2959172_0	1110697.NCAST_25_03590	2.9e-322	1005.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4FVQ3@85025|Nocardiaceae	201174|Actinobacteria	P	Heavy-metal-associated domain	copA	-	3.6.3.54	ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
BYD2_k127_2959172_31	66869.JNXG01000002_gene5667	2.569e-11	75.0	COG0662@1|root,COG0662@2|Bacteria,2IQE7@201174|Actinobacteria,41AZG@629295|Streptomyces griseus group	201174|Actinobacteria	G	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_2959172_24	1229780.BN381_100088	7.086e-40	149.0	COG3448@1|root,COG3448@2|Bacteria,2IJXV@201174|Actinobacteria	201174|Actinobacteria	T	HPP family	-	-	-	-	-	-	-	-	-	-	-	-	HPP
BYD2_k127_2984089_0	1211815.CBYP010000063_gene1912	2.213e-136	440.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
BYD2_k127_2984089_1	1211815.CBYP010000063_gene1913	1.357e-123	398.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
BYD2_k127_2992335_9	1229780.BN381_100118	2.006e-36	149.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07340,ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,LprI,NfeD,SDH_sah
BYD2_k127_2992335_2	1229780.BN381_100119	9.973e-93	317.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria,3UXHX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
BYD2_k127_2992335_1	1229780.BN381_100120	3.438e-116	400.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria,3UX1R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
BYD2_k127_2992335_11	1229780.BN381_100121	1.143e-31	135.0	COG1366@1|root,COG1366@2|Bacteria,2HPDM@201174|Actinobacteria,3UXK8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS
BYD2_k127_2992335_10	1229780.BN381_100122	7.343e-32	130.0	COG0745@1|root,COG0745@2|Bacteria	1229780.BN381_100122|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2992335_17	1038862.KB893806_gene2931	1.148e-05	53.0	COG0582@1|root,COG0582@2|Bacteria,1RBMJ@1224|Proteobacteria,2U0ET@28211|Alphaproteobacteria,3JYWG@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_2992335_13	67373.JOBF01000046_gene2694	2.722e-22	103.0	COG1051@1|root,COG1051@2|Bacteria,2I4EG@201174|Actinobacteria	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_2992335_12	591158.SSMG_00040	8.974e-30	125.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
BYD2_k127_2992335_8	345341.KUTG_02263	1.497e-43	163.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria,4DX87@85010|Pseudonocardiales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
BYD2_k127_2992335_6	386456.JQKN01000001_gene1795	9.201e-60	218.0	COG0330@1|root,arCOG01915@2157|Archaea,2XTA2@28890|Euryarchaeota,23PHG@183925|Methanobacteria	183925|Methanobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
BYD2_k127_2992335_18	158190.SpiGrapes_0105	3.176e-05	53.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	nfeD	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
BYD2_k127_2992335_0	1906.SFRA_28005	0.0	1039.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria	201174|Actinobacteria	P	ATPase P-type (Transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
BYD2_k127_2992335_4	1172181.KB911713_gene4408	2.251e-75	268.0	COG0569@1|root,COG0569@2|Bacteria,2HB3U@201174|Actinobacteria	201174|Actinobacteria	P	TrkA-N domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_N
BYD2_k127_2992335_5	1172181.KB911713_gene4409	2.183e-70	248.0	COG0569@1|root,COG0569@2|Bacteria,2GKB9@201174|Actinobacteria	201174|Actinobacteria	P	PFAM TrkA-N domain protein	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
BYD2_k127_2992335_15	1056816.JAFQ01000004_gene4423	1.362e-11	70.0	2AY0M@1|root,31Q26@2|Bacteria,2IMBI@201174|Actinobacteria,4G24E@85025|Nocardiaceae	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
BYD2_k127_2992335_3	1894.JOER01000062_gene101	1.506e-87	295.0	COG2162@1|root,COG2162@2|Bacteria,2GP1R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the arylamine N-acetyltransferase family	-	-	2.3.1.118	ko:K00675,ko:K15466	ko01051,ko01052,map01051,map01052	-	-	-	ko00000,ko00001,ko01000,ko01008	-	-	-	Acetyltransf_2
BYD2_k127_2992335_16	66373.JOFQ01000001_gene1884	3.016e-10	65.0	2E62U@1|root,330RX@2|Bacteria,2GTSM@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_2992335_7	1440053.JOEI01000007_gene2438	3.611e-47	184.0	COG0500@1|root,COG2226@2|Bacteria,2IAGR@201174|Actinobacteria	201174|Actinobacteria	Q	Nodulation protein S (NodS)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_2992335_14	1461694.ATO9_22535	2.863e-17	85.0	COG2197@1|root,COG2909@1|root,COG2197@2|Bacteria,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_3000546_0	1229780.BN381_300038	4.481e-82	288.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,3UXDP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	of an ABC-type transport system	-	-	-	-	-	-	-	-	-	-	-	-	OpuAC
BYD2_k127_3000546_2	1463936.JOJI01000025_gene1438	4.494e-49	196.0	COG1174@1|root,COG1174@2|Bacteria,2GYTC@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter (Permease)	proW	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
BYD2_k127_3000546_1	1229780.BN381_300040	2.096e-68	248.0	COG1174@1|root,COG1174@2|Bacteria,2GMU0@201174|Actinobacteria,3UXGB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K05846	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	BPD_transp_1
BYD2_k127_3000546_3	1380347.JNII01000006_gene1275	2.056e-28	120.0	COG0517@1|root,COG1125@1|root,COG0517@2|Bacteria,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,4ESFV@85013|Frankiales	201174|Actinobacteria	E	Product type t transporter	opuCA	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
BYD2_k127_3000614_22	1123320.KB889747_gene7192	1.367e-16	80.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria	201174|Actinobacteria	IQ	synthetase	fadD19	GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009605,GO:0009607,GO:0009987,GO:0015645,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019752,GO:0030312,GO:0032787,GO:0042546,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051087,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:0071944,GO:0075136,GO:1901576	6.2.1.42	ko:K00666,ko:K18688	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_3000614_20	479432.Sros_8868	6.413e-26	115.0	COG1309@1|root,COG1309@2|Bacteria,2H131@201174|Actinobacteria,4EQC9@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_3000614_4	479432.Sros_8869	4.087e-153	499.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4EFPE@85012|Streptosporangiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_3000614_2	330084.JNYZ01000020_gene4598	6.616e-213	679.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4DYT2@85010|Pseudonocardiales	201174|Actinobacteria	P	Flavin-binding monooxygenase-like	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase
BYD2_k127_3000614_21	1123024.AUII01000006_gene4554	4.398e-18	93.0	COG1309@1|root,COG1309@2|Bacteria,2GMNZ@201174|Actinobacteria,4E3N6@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_3000614_3	1229780.BN381_400017	1.555e-170	543.0	COG1960@1|root,COG1960@2|Bacteria,2GIXS@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_3000614_11	298655.KI912266_gene3406	1.202e-89	309.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EU2D@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
BYD2_k127_3000614_7	330084.JNYZ01000007_gene8852	7.174e-137	446.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,4DYUC@85010|Pseudonocardiales	201174|Actinobacteria	C	PFAM CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
BYD2_k127_3000614_18	1206737.BAGF01000058_gene3655	6.154e-44	172.0	COG4636@1|root,COG4636@2|Bacteria,2GW9A@201174|Actinobacteria	201174|Actinobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
BYD2_k127_3000614_16	1123023.JIAI01000003_gene3171	1.44e-56	204.0	COG3832@1|root,COG3832@2|Bacteria,2I3G9@201174|Actinobacteria,4EE5D@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_3000614_12	653045.Strvi_1870	2.907e-69	251.0	COG1225@1|root,COG1225@2|Bacteria,2IIDG@201174|Actinobacteria	201174|Actinobacteria	O	AhpC/TSA family	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,AhpC-TSA_2
BYD2_k127_3000614_13	103733.JNYO01000009_gene4621	5.658e-69	240.0	COG1309@1|root,COG1309@2|Bacteria,2IHQX@201174|Actinobacteria,4E4F0@85010|Pseudonocardiales	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
BYD2_k127_3000614_19	1122622.ATWJ01000013_gene79	1.432e-34	135.0	2DJKR@1|root,32YT5@2|Bacteria,2I86F@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3000614_10	1220534.B655_1022	1.873e-90	324.0	COG0025@1|root,arCOG01961@2157|Archaea,2XT52@28890|Euryarchaeota	28890|Euryarchaeota	P	COG0025 NhaP-type Na H and K H antiporters	kef1	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_C,TrkA_N
BYD2_k127_3000614_1	471852.Tcur_1862	2.07e-244	768.0	COG0511@1|root,COG4799@1|root,COG0511@2|Bacteria,COG4799@2|Bacteria,2I46V@201174|Actinobacteria	201174|Actinobacteria	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl,Carboxyl_trans
BYD2_k127_3000614_8	1229780.BN381_80127	5.866e-110	363.0	COG1028@1|root,COG1028@2|Bacteria,2GK47@201174|Actinobacteria,3UXC4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	KR domain	rhlG	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
BYD2_k127_3000614_14	1146883.BLASA_3115	1.246e-68	254.0	COG1597@1|root,COG1597@2|Bacteria,2GNTZ@201174|Actinobacteria	201174|Actinobacteria	I	lipid kinase activity	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
BYD2_k127_3000614_6	591167.Sfla_0345	6.517e-141	457.0	COG1502@1|root,COG1502@2|Bacteria,2GM0P@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
BYD2_k127_3000614_9	1464048.JNZS01000033_gene2794	3.873e-104	355.0	COG1075@1|root,COG1075@2|Bacteria,2HXFM@201174|Actinobacteria,4DI5G@85008|Micromonosporales	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_2
BYD2_k127_3000614_17	471852.Tcur_3213	3.627e-49	192.0	COG0477@1|root,COG2814@2|Bacteria,2H8PB@201174|Actinobacteria,4EFTY@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_3000614_5	1229780.BN381_130250	2.197e-152	494.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_3000614_0	1121946.AUAX01000001_gene2119	2.684e-249	786.0	COG2373@1|root,COG2373@2|Bacteria,2H4M3@201174|Actinobacteria,4DCH5@85008|Micromonosporales	201174|Actinobacteria	G	Animal haem peroxidase	-	-	-	-	-	-	-	-	-	-	-	-	An_peroxidase
BYD2_k127_3000614_15	68170.KL590542_gene11400	2.528e-61	217.0	COG1309@1|root,COG1309@2|Bacteria,2HAUK@201174|Actinobacteria,4E5WT@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_3035799_2	471852.Tcur_2020	3.726e-05	47.0	COG1670@1|root,COG1670@2|Bacteria,2GR79@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
BYD2_k127_3079870_7	1229780.BN381_10192	3.038e-54	203.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,3UWUN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
BYD2_k127_3079870_0	1211815.CBYP010000045_gene810	5.625e-205	662.0	COG0726@1|root,COG1215@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Polysacc_deac_1
BYD2_k127_3079870_6	1089546.AQUI01000002_gene2055	1.116e-63	248.0	COG3858@1|root,COG3858@2|Bacteria,2HZ7I@201174|Actinobacteria,409RI@622450|Actinopolysporales	201174|Actinobacteria	S	Glycosyl hydrolases family 18	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18
BYD2_k127_3079870_5	1121877.JQKF01000001_gene1361	1.152e-75	268.0	COG0438@1|root,COG0438@2|Bacteria,2GIVP@201174|Actinobacteria,4CN35@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_3079870_2	1229780.BN381_10190	3.403e-113	372.0	COG1089@1|root,COG1089@2|Bacteria,2GNMA@201174|Actinobacteria	201174|Actinobacteria	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	-	-	1.1.1.281	ko:K15856	ko00051,ko00520,map00051,map00520	-	R03397,R03399	RC00182	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
BYD2_k127_3079870_1	867845.KI911784_gene1522	1.572e-169	537.0	COG1089@1|root,COG1089@2|Bacteria,2G5P2@200795|Chloroflexi,375CR@32061|Chloroflexia	32061|Chloroflexia	M	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose	gmd	-	4.2.1.47	ko:K01711	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R00888	RC00402	ko00000,ko00001,ko01000	-	-	-	GDP_Man_Dehyd
BYD2_k127_3079870_3	1313172.YM304_28610	6.282e-93	322.0	COG0391@1|root,COG0391@2|Bacteria,2GJZ2@201174|Actinobacteria,4CN0F@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein family UPF0052	-	-	2.7.8.28	ko:K11212	ko00680,ko01120,map00680,map01120	M00378	R09398	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	UPF0052
BYD2_k127_3079870_4	1229780.BN381_10186	2.421e-87	294.0	COG1478@1|root,COG1478@2|Bacteria,2GMJ8@201174|Actinobacteria,3UXCJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	F420-0:Gamma-glutamyl ligase	fbiB	GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016020,GO:0044237,GO:0044249,GO:0044464,GO:0051186,GO:0051188,GO:0071944	6.3.2.31,6.3.2.34	ko:K12234	ko00680,ko01120,map00680,map01120	M00378	R09399,R09400	RC00064,RC00090,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_ligase,Nitroreductase
BYD2_k127_3079870_8	1304865.JAGF01000001_gene83	1.488e-51	186.0	COG4319@1|root,COG4319@2|Bacteria,2IPRQ@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_3103683_1	66874.JOFS01000003_gene7103	4.363e-123	396.0	COG0262@1|root,COG0262@2|Bacteria,2GMZV@201174|Actinobacteria	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_3103683_4	1380386.JIAW01000004_gene88	5.169e-75	258.0	COG0684@1|root,COG0684@2|Bacteria,2IH5H@201174|Actinobacteria,237HZ@1762|Mycobacteriaceae	201174|Actinobacteria	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
BYD2_k127_3103683_5	1380393.JHVP01000004_gene615	1.005e-68	249.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4ESAF@85013|Frankiales	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
BYD2_k127_3103683_7	656024.FsymDg_2709	5.907e-63	228.0	COG2197@1|root,COG2197@2|Bacteria,2GJHH@201174|Actinobacteria,4ESAK@85013|Frankiales	201174|Actinobacteria	K	Two component transcriptional regulator, LuxR family	-	-	-	ko:K07696	ko02020,map02020	M00483	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	GerE,Response_reg
BYD2_k127_3103683_8	172088.AUGA01000003_gene5673	1.436e-15	89.0	COG2050@1|root,COG2050@2|Bacteria,1RK46@1224|Proteobacteria,2U29Q@28211|Alphaproteobacteria,3JW02@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	Q	Domain of unknown function (DUF4442)	MA20_27405	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_3103683_9	882083.SacmaDRAFT_3624	1.995e-11	68.0	COG3462@1|root,COG3462@2|Bacteria,2GWIQ@201174|Actinobacteria,4E7TB@85010|Pseudonocardiales	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
BYD2_k127_3103683_3	1121272.KB903279_gene6980	2.83e-90	304.0	COG1131@1|root,COG1131@2|Bacteria,2GP3F@201174|Actinobacteria,4DCSH@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
BYD2_k127_3103683_2	1957.JODX01000007_gene2136	1.341e-122	414.0	28JCJ@1|root,2Z977@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
BYD2_k127_3103683_0	1410634.JHVD01000027_gene1655	0.0	1076.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DPNE@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	Cupredoxin_1,E1-E2_ATPase,HMA,Hydrolase,YHS
BYD2_k127_3103683_6	1122138.AQUZ01000019_gene8190	8.573e-66	233.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	2|Bacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
BYD2_k127_3103683_10	713587.THITH_02995	6.67e-08	63.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18,3.4.11.10	ko:K01186,ko:K05994	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko01002,ko02042	-	GH33	-	PA,PKD,fn3
BYD2_k127_3130732_0	1150864.MILUP08_46453	0.0	1280.0	COG2374@1|root,COG2374@2|Bacteria,2HTX5@201174|Actinobacteria,4D99T@85008|Micromonosporales	201174|Actinobacteria	S	Lamin Tail Domain	-	-	-	ko:K07004	-	-	-	-	ko00000	-	-	-	Exo_endo_phos,LTD
BYD2_k127_3130732_1	1229780.BN381_150069	0.0	1008.0	COG2185@1|root,COG2185@2|Bacteria,2I2N3@201174|Actinobacteria,3UX6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	B12 binding domain	meaA	-	5.4.99.63	ko:K14447	ko00630,ko01120,ko01200,map00630,map01120,map01200	M00373	R09292	RC02835	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
BYD2_k127_3130732_5	1048339.KB913029_gene4637	3.361e-91	309.0	COG2360@1|root,COG2360@2|Bacteria,2IFT7@201174|Actinobacteria,4EVRP@85013|Frankiales	201174|Actinobacteria	O	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine	aat	-	2.3.2.6	ko:K00684	-	-	R03813,R11443,R11444	RC00055,RC00064	ko00000,ko01000	-	-	-	Leu_Phe_trans
BYD2_k127_3130732_4	1229780.BN381_100132	1.362e-114	375.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,3UX97@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain	-	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
BYD2_k127_3130732_6	1229780.BN381_100131	5.688e-56	203.0	COG4242@1|root,COG4242@2|Bacteria	2|Bacteria	PQ	Belongs to the peptidase S51 family	cphB	-	3.4.15.6	ko:K13282	-	-	R09722	RC00064,RC00141	ko00000,ko01000,ko01002	-	-	-	Peptidase_S51
BYD2_k127_3130732_3	1172188.KB911820_gene2749	3.192e-183	578.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4FEE3@85021|Intrasporangiaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
BYD2_k127_3130732_2	1184607.AUCHE_05_04270	1.615e-189	599.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
BYD2_k127_3130952_10	1298863.AUEP01000001_gene1038	1.889e-15	79.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4DNV7@85009|Propionibacteriales	201174|Actinobacteria	EG	Belongs to the IlvD Edd family	ilvD	GO:0003674,GO:0003824,GO:0004160,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
BYD2_k127_3130952_9	58123.JOFJ01000007_gene683	2.176e-26	126.0	COG5662@1|root,COG5662@2|Bacteria,2I4J2@201174|Actinobacteria	201174|Actinobacteria	K	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,zf-HC2
BYD2_k127_3130952_8	28444.JODQ01000007_gene5549	1.261e-47	178.0	COG1595@1|root,COG1595@2|Bacteria,2GKGB@201174|Actinobacteria,4EJHK@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_3130952_0	1229780.BN381_80039	6.344e-313	967.0	COG0028@1|root,COG0028@2|Bacteria,2GKU4@201174|Actinobacteria,3UWFJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Thiamine pyrophosphate enzyme, central domain	ilvB	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030312,GO:0030976,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3003c	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
BYD2_k127_3130952_6	1313172.YM304_11440	4.281e-57	216.0	COG0440@1|root,COG0440@2|Bacteria,2GJCH@201174|Actinobacteria,4CN3W@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ACT domain	-	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT_5,ALS_ss_C
BYD2_k127_3130952_1	1229780.BN381_80043	1.283e-166	532.0	COG0059@1|root,COG0059@2|Bacteria,2GKXA@201174|Actinobacteria,3UWCK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008677,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
BYD2_k127_3130952_11	1464048.JNZS01000007_gene4551	1.235e-07	65.0	COG5401@1|root,COG5401@2|Bacteria,2IRGJ@201174|Actinobacteria,4DF2T@85008|Micromonosporales	201174|Actinobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
BYD2_k127_3130952_4	1313172.YM304_24120	1.753e-92	320.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_3130952_7	55952.BU52_17070	6.602e-52	186.0	COG3467@1|root,COG3467@2|Bacteria,2IFRI@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
BYD2_k127_3130952_5	1280954.HPO_12958	1.021e-89	310.0	COG1680@1|root,COG1680@2|Bacteria,1MY4Y@1224|Proteobacteria,2U8KF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_3130952_3	369723.Strop_1651	2.183e-139	467.0	COG0443@1|root,COG3266@1|root,COG0443@2|Bacteria,COG3266@2|Bacteria,2GNTE@201174|Actinobacteria,4DM1N@85008|Micromonosporales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
BYD2_k127_3130952_2	1282876.BAOK01000002_gene557	2.667e-144	477.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2TR2W@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BYD2_k127_3173393_30	1229780.BN381_450005	3.504e-68	232.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,3UWJQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
BYD2_k127_3173393_38	1313172.YM304_04060	6.862e-42	160.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,4CN51@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	-	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
BYD2_k127_3173393_45	1313172.YM304_04050	5.212e-28	124.0	2FE68@1|root,34663@2|Bacteria,2H83B@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3173393_27	1229780.BN381_450008	2.099e-73	264.0	COG2010@1|root,COG2010@2|Bacteria,2H49G@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome C oxidase, cbb3-type, subunit III	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
BYD2_k127_3173393_15	1229780.BN381_450009	3.108e-100	337.0	COG0723@1|root,COG0723@2|Bacteria,2H0R5@201174|Actinobacteria	201174|Actinobacteria	C	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
BYD2_k127_3173393_14	1229780.BN381_450010	1.853e-100	334.0	COG1290@1|root,COG1290@2|Bacteria,2H1Y8@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b(C-terminal)/b6/petD	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B_C
BYD2_k127_3173393_4	1229780.BN381_450011	7.135e-147	468.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome b	-	-	-	ko:K03887	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_B
BYD2_k127_3173393_24	1229780.BN381_450012	2.326e-75	254.0	COG1143@1|root,COG1143@2|Bacteria,2H4NQ@201174|Actinobacteria	201174|Actinobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10
BYD2_k127_3173393_41	1229780.BN381_450013	1.562e-36	143.0	2C3UQ@1|root,341WW@2|Bacteria,2H6NT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3173393_56	1229780.BN381_450015	7.376e-07	54.0	COG2010@1|root,COG2010@2|Bacteria,2H5KX@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3173393_42	1229780.BN381_450015	2.297e-31	129.0	COG2010@1|root,COG2010@2|Bacteria,2H5KX@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3173393_1	1229780.BN381_450016	2.649e-191	618.0	COG0644@1|root,COG0644@2|Bacteria,2GKGH@201174|Actinobacteria,3UX9K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD binding domain	menJ	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016491,GO:0016627,GO:0030312,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663	1.3.99.38	ko:K21401	-	-	-	-	ko00000,ko01000	-	-	-	FAD_binding_3
BYD2_k127_3173393_49	1313172.YM304_37260	3.429e-14	78.0	COG3794@1|root,COG3794@2|Bacteria,2HH58@201174|Actinobacteria,4CP4V@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
BYD2_k127_3173393_44	1313172.YM304_33880	2.689e-29	136.0	COG0682@1|root,COG0682@2|Bacteria,2HGGR@201174|Actinobacteria,4CNDX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	-	-	-	-	-	-	-	-	-	LGT
BYD2_k127_3173393_2	1267535.KB906767_gene3855	4.416e-155	515.0	COG0364@1|root,COG0364@2|Bacteria,3Y627@57723|Acidobacteria,2JKTN@204432|Acidobacteriia	204432|Acidobacteriia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	-	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
BYD2_k127_3173393_11	269800.Tfu_0003	3.828e-113	375.0	COG1023@1|root,COG1023@2|Bacteria,2I2DH@201174|Actinobacteria,4EHS7@85012|Streptosporangiales	201174|Actinobacteria	G	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
BYD2_k127_3173393_8	314278.NB231_09548	1.184e-124	439.0	COG0166@1|root,COG0176@1|root,COG0166@2|Bacteria,COG0176@2|Bacteria,1MUFP@1224|Proteobacteria	1224|Proteobacteria	G	Belongs to the GPI family	tal	-	2.2.1.2,5.3.1.9	ko:K01810,ko:K13810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00004,M00007,M00114	R01827,R02739,R02740,R03321	RC00376,RC00439,RC00563,RC00604	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI,TAL_FSA
BYD2_k127_3173393_3	1313172.YM304_37790	8.559e-150	484.0	COG0001@1|root,COG0001@2|Bacteria,2GJSH@201174|Actinobacteria,4CMTZ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Aminotransferase class-III	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
BYD2_k127_3173393_33	1229780.BN381_500002	4.001e-58	229.0	COG3568@1|root,COG3568@2|Bacteria,2HQV4@201174|Actinobacteria	201174|Actinobacteria	M	Jacalin-like lectin domain	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos,Jacalin
BYD2_k127_3173393_5	1229780.BN381_60037	4.04e-138	445.0	COG0113@1|root,COG0113@2|Bacteria,2GJJ0@201174|Actinobacteria,3UW8S@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Delta-aminolevulinic acid dehydratase	hemB	GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
BYD2_k127_3173393_34	1229780.BN381_130109	1.962e-57	217.0	COG0683@1|root,COG0683@2|Bacteria,2HN41@201174|Actinobacteria,3UXIC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
BYD2_k127_3173393_32	1229780.BN381_130108	1.134e-62	241.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,3UXF4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_3173393_31	66874.JOFS01000005_gene3824	6.793e-68	251.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_3173393_20	1313172.YM304_30760	1.895e-85	291.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4CN2Y@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_3173393_16	298654.FraEuI1c_3249	2.661e-96	321.0	COG0411@1|root,COG0411@2|Bacteria,2IJ5Y@201174|Actinobacteria,4EV5P@85013|Frankiales	201174|Actinobacteria	E	Evidence 2a Function of homologous gene experimentally demonstrated in an other organism	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_3173393_10	469383.Cwoe_5880	1.92e-119	415.0	COG0007@1|root,COG1587@1|root,COG0007@2|Bacteria,COG1587@2|Bacteria,2GK3B@201174|Actinobacteria,4CPJJ@84995|Rubrobacteria	84995|Rubrobacteria	H	Uroporphyrinogen-III synthase HemD	-	-	2.1.1.107,4.2.1.75	ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165,R03194	RC00003,RC00871,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,TP_methylase
BYD2_k127_3173393_25	1125863.JAFN01000001_gene1122	5.161e-75	274.0	COG0181@1|root,COG0181@2|Bacteria,1MU56@1224|Proteobacteria,42M84@68525|delta/epsilon subdivisions,2WJ5V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps	hemC	GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.61	ko:K01749	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00084	RC02317	ko00000,ko00001,ko00002,ko01000	-	-	-	Porphobil_deam,Porphobil_deamC
BYD2_k127_3173393_13	1313172.YM304_37850	1.384e-106	360.0	COG0373@1|root,COG0373@2|Bacteria,2GJRA@201174|Actinobacteria,4CN61@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,Shikimate_DH
BYD2_k127_3173393_39	1121428.DESHY_10149___1	1.079e-40	158.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,2625C@186807|Peptococcaceae	186801|Clostridia	H	TIGRFAM siroheme synthase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
BYD2_k127_3173393_21	452652.KSE_33640	1.046e-83	283.0	COG2344@1|root,COG2344@2|Bacteria,2GMV2@201174|Actinobacteria,2M0T9@2063|Kitasatospora	201174|Actinobacteria	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
BYD2_k127_3173393_7	1089545.KB913037_gene1902	1.135e-130	433.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria,4E9IR@85010|Pseudonocardiales	201174|Actinobacteria	J	Amidase	zhuL	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
BYD2_k127_3173393_12	1313172.YM304_31060	3.841e-112	391.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BYD2_k127_3173393_18	1313172.YM304_37870	4.601e-91	308.0	COG1912@1|root,COG1912@2|Bacteria,2IASJ@201174|Actinobacteria	201174|Actinobacteria	S	transferase activity, transferring alkyl or aryl (other than methyl) groups	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
BYD2_k127_3173393_51	397278.JOJN01000002_gene366	2.003e-13	73.0	COG3311@1|root,COG3311@2|Bacteria,2GQGV@201174|Actinobacteria,4DS39@85009|Propionibacteriales	201174|Actinobacteria	K	Helix-turn-helix domain	xis	-	-	-	-	-	-	-	-	-	-	-	HTH_17
BYD2_k127_3173393_29	1229780.BN381_60047	9.144e-72	252.0	COG0345@1|root,COG0345@2|Bacteria,2GJ7D@201174|Actinobacteria,3UWS1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
BYD2_k127_3173393_40	1313172.YM304_37890	4.88e-38	147.0	2AZ39@1|root,31R9K@2|Bacteria,2GMCY@201174|Actinobacteria	201174|Actinobacteria	S	Putative bacterial sensory transduction regulator	-	-	-	-	-	-	-	-	-	-	-	-	YbjN
BYD2_k127_3173393_6	1313172.YM304_37900	9.671e-131	430.0	COG0297@1|root,COG0438@1|root,COG0297@2|Bacteria,COG0438@2|Bacteria,2GJ57@201174|Actinobacteria,4CMYV@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferase 4-like domain	-	-	2.4.1.250	ko:K15521	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_3173393_23	1121935.AQXX01000097_gene1731	5.053e-80	274.0	COG0605@1|root,COG0605@2|Bacteria,1MVW2@1224|Proteobacteria,1RP7X@1236|Gammaproteobacteria,1XHSZ@135619|Oceanospirillales	135619|Oceanospirillales	C	Destroys radicals which are normally produced within the cells and which are toxic to biological systems	sodB	-	1.15.1.1	ko:K04564	ko04013,ko04068,ko04146,ko04211,ko04212,ko04213,ko05016,map04013,map04068,map04146,map04211,map04212,map04213,map05016	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Fe_C,Sod_Fe_N
BYD2_k127_3173393_47	1313172.YM304_37920	2.222e-21	102.0	COG1977@1|root,COG1977@2|Bacteria	2|Bacteria	H	Mo-molybdopterin cofactor metabolic process	moaD	-	2.8.1.12	ko:K03636,ko:K21142	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE,ThiS
BYD2_k127_3173393_36	1229780.BN381_60053	1.212e-53	195.0	COG0406@1|root,COG0406@2|Bacteria,2GJ9R@201174|Actinobacteria,3UWZM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Belongs to the phosphoglycerate mutase family	-	-	-	ko:K15640	-	-	-	-	ko00000	-	-	-	His_Phos_1
BYD2_k127_3173393_55	443906.CMM_2277	2.622e-08	60.0	COG1734@1|root,COG1734@2|Bacteria,2GJBE@201174|Actinobacteria,4FQIV@85023|Microbacteriaceae	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
BYD2_k127_3173393_59	2045.KR76_05620	6.241e-05	52.0	COG1404@1|root,COG4188@1|root,COG1404@2|Bacteria,COG4188@2|Bacteria,2I3KQ@201174|Actinobacteria,4DN0K@85009|Propionibacteriales	201174|Actinobacteria	O	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,Calx-beta,Chlorophyllase2
BYD2_k127_3173393_0	350058.Mvan_2010	2.919e-218	692.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,232FY@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD19_2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_3173393_57	1313172.YM304_02450	2.951e-05	55.0	2DH1Q@1|root,2ZY32@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF2510)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510
BYD2_k127_3173393_22	298654.FraEuI1c_4744	3.494e-83	286.0	COG1793@1|root,COG1793@2|Bacteria,2IKE5@201174|Actinobacteria,4ESAR@85013|Frankiales	201174|Actinobacteria	L	DNA polymerase LigD, ligase domain protein	ligD	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
BYD2_k127_3173393_58	1123239.KB898636_gene2799	6.235e-05	51.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli	91061|Bacilli	T	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
BYD2_k127_3173393_19	1229780.BN381_130288	2.258e-88	313.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,3UWVR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	ABC 3 transport family	mntB	-	-	ko:K09819,ko:K11602,ko:K19975,ko:K19976	ko02010,ko02020,map02010,map02020	M00243,M00316,M00792	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15,3.A.1.15.1,3.A.1.15.15	-	-	ABC-3
BYD2_k127_3173393_17	1229780.BN381_130287	8.365e-95	320.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria,3UXDF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	3.6.3.35	ko:K09820,ko:K11710,ko:K19973	ko02010,map02010	M00243,M00319,M00792	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.15,3.A.1.15.15	-	-	ABC_tran
BYD2_k127_3173393_9	1229780.BN381_130286	2.127e-121	398.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,3UWXB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	-	-	-	ko:K09818	-	M00243	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
BYD2_k127_3173393_37	1313172.YM304_38230	1.841e-49	182.0	COG0756@1|root,COG0756@2|Bacteria,2IHYY@201174|Actinobacteria,4CN99@84992|Acidimicrobiia	84992|Acidimicrobiia	F	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
BYD2_k127_3173393_28	1313172.YM304_38580	3.619e-73	255.0	COG1949@1|root,COG1949@2|Bacteria,2GJR7@201174|Actinobacteria,4CN0M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	3'-to-5' exoribonuclease specific for small oligoribonucleotides	orn	-	-	ko:K13288	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	RNase_T
BYD2_k127_3173393_43	1313172.YM304_38500	2.749e-31	130.0	2DMIS@1|root,32RVG@2|Bacteria,2IQ99@201174|Actinobacteria	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB7	GO:0001101,GO:0008150,GO:0010033,GO:0033993,GO:0042221,GO:0046677,GO:0050896,GO:0070542,GO:1901700	-	ko:K18958	-	-	-	-	ko00000,ko03000	-	-	-	AT_hook,Whib
BYD2_k127_3173393_46	926560.KE387023_gene3475	2.062e-21	107.0	COG0526@1|root,COG0526@2|Bacteria,1WJ2P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	CO	periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily	ccmG	-	-	ko:K02199	-	-	-	-	ko00000,ko03110	-	-	-	AhpC-TSA
BYD2_k127_3173393_35	1048339.KB913029_gene2808	3.246e-56	218.0	COG0785@1|root,COG0785@2|Bacteria,2I8T6@201174|Actinobacteria,4EVDM@85013|Frankiales	201174|Actinobacteria	O	Cytochrome c biogenesis protein transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	DsbD
BYD2_k127_3173393_26	235985.BBPN01000029_gene2382	1.287e-73	253.0	COG0259@1|root,COG0259@2|Bacteria,2GJCR@201174|Actinobacteria,2NEDK@228398|Streptacidiphilus	201174|Actinobacteria	H	Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region	pdxH	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0010181,GO:0016491,GO:0016614,GO:0016899,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032553,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042803,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	1.4.3.5	ko:K00275	ko00750,ko01100,ko01120,map00750,map01100,map01120	M00124	R00277,R00278,R01710,R01711	RC00048,RC00116	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2607	PNP_phzG_C,Putative_PNPOx
BYD2_k127_3173393_50	500153.JOEK01000001_gene3778	4.23e-14	84.0	COG1737@1|root,COG1737@2|Bacteria,2GMN2@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
BYD2_k127_3173393_52	471857.Svir_23570	1.349e-11	73.0	COG0436@1|root,COG0436@2|Bacteria,2GM3B@201174|Actinobacteria,4DZ77@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
BYD2_k127_3173393_53	66373.JOFQ01000003_gene5712	9.943e-11	68.0	COG0436@1|root,COG0436@2|Bacteria,2GM3B@201174|Actinobacteria	201174|Actinobacteria	E	COG0436 Aspartate tyrosine aromatic aminotransferase	-	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
BYD2_k127_3211433_6	1348663.KCH_09190	6.22e-10	63.0	COG0510@1|root,COG0510@2|Bacteria,2GMFN@201174|Actinobacteria,2M4IM@2063|Kitasatospora	201174|Actinobacteria	M	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_3211433_4	670307.HYPDE_33248	6.793e-26	114.0	COG1917@1|root,COG1917@2|Bacteria	2|Bacteria	L	Cupin 2, conserved barrel domain protein	nbaC	GO:0000334,GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0044237,GO:0044248,GO:0051213,GO:0055114	1.13.11.6	ko:K00452	ko00380,ko01100,map00380,map01100	M00038	R02665	RC00387	ko00000,ko00001,ko00002,ko01000	-	-	-	3-HAO,Cupin_2
BYD2_k127_3211433_3	1206744.BAGL01000065_gene4899	3.694e-53	197.0	COG0500@1|root,COG2226@2|Bacteria,2HJCZ@201174|Actinobacteria,4G6D4@85025|Nocardiaceae	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_3211433_5	1111479.AXAR01000031_gene1476	3.149e-20	97.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,4HIQX@91061|Bacilli,27A65@186823|Alicyclobacillaceae	91061|Bacilli	K	Acetyltransferase (GNAT) domain	yxbD	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Acetyltransf_1
BYD2_k127_3211433_2	1229780.BN381_210048	4.759e-80	272.0	COG4430@1|root,COG4430@2|Bacteria,2II0D@201174|Actinobacteria,3UXQY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
BYD2_k127_3211433_7	1229780.BN381_100174	0.0002121	54.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF3566
BYD2_k127_3211433_0	1313172.YM304_00070	0.0	1060.0	COG0188@1|root,COG0188@2|Bacteria,2GJ2Q@201174|Actinobacteria,4CMSQ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	DNA Topoisomerase IV	-	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
BYD2_k127_3211433_1	1313172.YM304_00060	1.605e-117	381.0	COG0187@1|root,COG0187@2|Bacteria,2GKGP@201174|Actinobacteria,4CMQZ@84992|Acidimicrobiia	84992|Acidimicrobiia	L	TopoisomeraseII	-	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
BYD2_k127_3250925_0	196162.Noca_2938	1.448e-85	295.0	COG5002@1|root,COG5002@2|Bacteria,2GIX7@201174|Actinobacteria,4DTJI@85009|Propionibacteriales	201174|Actinobacteria	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_3250925_1	1035308.AQYY01000001_gene3215	1.873e-83	285.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07668,ko:K07775	ko02020,map02020	M00458,M00459	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_3250925_4	710696.Intca_2711	4.123e-05	55.0	2B3SZ@1|root,31WGK@2|Bacteria,2GYUG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3250925_3	1380356.JNIK01000015_gene2511	1.841e-31	127.0	COG3439@1|root,COG3439@2|Bacteria,2IKVF@201174|Actinobacteria,4ET57@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	DUF302
BYD2_k127_3250925_5	649831.L083_4261	0.0002442	53.0	COG1520@1|root,COG1520@2|Bacteria,2HWS1@201174|Actinobacteria,4DK60@85008|Micromonosporales	201174|Actinobacteria	S	beta-propeller repeat	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2
BYD2_k127_3250925_2	1123023.JIAI01000001_gene7656	1.208e-67	243.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,4E28A@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_3260277_3	1048339.KB913029_gene2994	8.114e-26	111.0	COG0642@1|root,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria,4ESNT@85013|Frankiales	201174|Actinobacteria	T	Response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,GAF_2,HAMP,HATPase_c,HisKA,PAS_4,Response_reg
BYD2_k127_3260277_1	1206737.BAGF01000084_gene5485	6.508e-92	312.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4FUZK@85025|Nocardiaceae	201174|Actinobacteria	EG	EamA-like transporter family	cyeA	-	-	-	-	-	-	-	-	-	-	-	EamA
BYD2_k127_3260277_2	1121481.AUAS01000006_gene588	1.489e-30	130.0	2B9NZ@1|root,3231D@2|Bacteria,4NR0T@976|Bacteroidetes	976|Bacteroidetes	S	Protein of unknown function (DUF1579)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1579
BYD2_k127_3260277_0	525909.Afer_0306	2.139e-123	409.0	COG0215@1|root,COG0215@2|Bacteria,2GJF2@201174|Actinobacteria,4CMTW@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Belongs to the class-I aminoacyl-tRNA synthetase family	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e
BYD2_k127_3260277_4	1120959.ATXF01000004_gene2589	0.0004335	46.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FMWW@85023|Microbacteriaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
BYD2_k127_3261217_1	356851.JOAN01000029_gene4970	1.298e-97	327.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4DD0R@85008|Micromonosporales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,NmrA
BYD2_k127_3261217_0	1353531.AZNX01000008_gene715	1.974e-124	400.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2TTHB@28211|Alphaproteobacteria,4B9T6@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	Bacterial protein of unknown function (DUF899)	MA20_01595	-	-	-	-	-	-	-	-	-	-	-	DUF899
BYD2_k127_3261217_2	1313172.YM304_04330	7.593e-54	192.0	COG4270@1|root,COG4270@2|Bacteria,2IKKP@201174|Actinobacteria	201174|Actinobacteria	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
BYD2_k127_3261217_3	479435.Kfla_5396	1.61e-46	181.0	COG0640@1|root,COG0640@2|Bacteria,2GP04@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_3261217_5	525904.Tter_0384	5.18e-33	138.0	COG2259@1|root,COG2259@2|Bacteria	2|Bacteria	S	methylamine metabolic process	doxD	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
BYD2_k127_3261217_6	469383.Cwoe_1110	1.179e-31	137.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3261217_4	1440774.Y900_018595	6.554e-34	136.0	COG1902@1|root,COG1902@2|Bacteria,2IHUT@201174|Actinobacteria,239AX@1762|Mycobacteriaceae	201174|Actinobacteria	C	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
BYD2_k127_3261217_7	526225.Gobs_3634	4.142e-21	96.0	COG0300@1|root,COG0300@2|Bacteria,2IGCX@201174|Actinobacteria,4EVA1@85013|Frankiales	201174|Actinobacteria	S	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_3275312_20	1313172.YM304_22230	2.14e-07	55.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4CN1J@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
BYD2_k127_3275312_1	1313172.YM304_22240	1.85e-239	749.0	COG3875@1|root,COG3875@2|Bacteria,2IAM4@201174|Actinobacteria,4CMV3@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
BYD2_k127_3275312_17	500153.JOEK01000011_gene1867	1.689e-22	112.0	COG3631@1|root,COG3631@2|Bacteria,2IM60@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_3275312_7	266117.Rxyl_2111	4.403e-85	319.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_3275312_0	1313172.YM304_22260	0.0	1026.0	COG0560@1|root,COG3320@1|root,COG0560@2|Bacteria,COG3320@2|Bacteria,2GJVX@201174|Actinobacteria,4CMQQ@84992|Acidimicrobiia	84992|Acidimicrobiia	EQ	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD,NAD_binding_4
BYD2_k127_3275312_12	1313172.YM304_22270	1.428e-46	175.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	ko:K09017	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
BYD2_k127_3275312_14	1449976.KALB_4498	1.448e-34	145.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria,4E225@85010|Pseudonocardiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_3275312_3	1415754.JQMK01000012_gene909	6.907e-170	556.0	COG2234@1|root,COG2234@2|Bacteria,1MV86@1224|Proteobacteria,1RNNQ@1236|Gammaproteobacteria,464MC@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
BYD2_k127_3275312_6	479432.Sros_5116	1.53e-112	369.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria,4EIEK@85012|Streptosporangiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_3275312_18	1429046.RR21198_4379	1.231e-17	89.0	2BKDI@1|root,32EU7@2|Bacteria,2HJMF@201174|Actinobacteria,4G71C@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3275312_16	1240349.ANGC01000002_gene2260	1.238e-33	136.0	2AQK7@1|root,31FT5@2|Bacteria,2HADC@201174|Actinobacteria,4G6NU@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_3275312_13	66429.JOFL01000033_gene4005	3.165e-46	173.0	COG3557@1|root,COG3557@2|Bacteria,2IFIQ@201174|Actinobacteria	201174|Actinobacteria	J	Protein of unknown function (DUF402)	-	-	-	ko:K07586	-	-	-	-	ko00000	-	-	-	DUF402
BYD2_k127_3275312_10	675635.Psed_0911	2.509e-58	206.0	COG3324@1|root,COG3324@2|Bacteria	2|Bacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
BYD2_k127_3275312_9	1463917.JODC01000005_gene6472	1.647e-61	217.0	COG0748@1|root,COG0748@2|Bacteria,2INF5@201174|Actinobacteria	201174|Actinobacteria	P	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_3275312_5	258052.JNYV01000002_gene1542	1.26e-128	422.0	COG1181@1|root,COG1181@2|Bacteria,2GITC@201174|Actinobacteria,2M0JG@2063|Kitasatospora	201174|Actinobacteria	M	D-ala D-ala ligase N-terminus	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
BYD2_k127_3275312_4	1172185.KB911512_gene5025	5.062e-135	446.0	COG0770@1|root,COG0770@2|Bacteria,2GK0Y@201174|Actinobacteria,4FWIU@85025|Nocardiaceae	201174|Actinobacteria	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
BYD2_k127_3275312_8	1229780.BN381_80413	3.05e-84	297.0	COG0477@1|root,COG2814@2|Bacteria,2I2EY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
BYD2_k127_3275312_19	1193181.BN10_930025	1.804e-10	74.0	2DECH@1|root,2ZMD6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3275312_11	1121877.JQKF01000035_gene1966	2.108e-56	214.0	COG1329@1|root,COG1329@2|Bacteria,2GKSU@201174|Actinobacteria,4CN2D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
BYD2_k127_3275312_2	1229780.BN381_210110	6.418e-176	578.0	COG1960@1|root,COG1960@2|Bacteria,2HY6H@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE21	-	-	ko:K00257	-	-	R04547,R04592	RC01942	ko00000,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_3275312_15	1123023.JIAI01000010_gene8515	6.622e-34	130.0	COG1960@1|root,COG1960@2|Bacteria,2GM3V@201174|Actinobacteria,4DXM5@85010|Pseudonocardiales	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_3286843_6	1120950.KB892811_gene7253	4.819e-25	111.0	COG1895@1|root,COG1895@2|Bacteria,2I82C@201174|Actinobacteria	201174|Actinobacteria	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3286843_3	1123024.AUII01000001_gene3029	1.454e-57	226.0	COG0428@1|root,COG0428@2|Bacteria,2ICIQ@201174|Actinobacteria	201174|Actinobacteria	P	Mediates zinc uptake. May also transport other divalent cations	zupT	-	-	-	-	-	-	-	-	-	-	-	Zip
BYD2_k127_3286843_1	1121378.KB899704_gene2420	7.613e-116	382.0	COG2132@1|root,COG2132@2|Bacteria,1WJQI@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
BYD2_k127_3286843_7	251221.35214868	6.489e-15	83.0	COG2146@1|root,COG2146@2|Bacteria,1G9AZ@1117|Cyanobacteria	1117|Cyanobacteria	P	of nitrite reductase and ring-hydroxylating dioxygenase	-	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
BYD2_k127_3286843_2	1173026.Glo7428_2181	1.115e-92	310.0	COG2406@1|root,COG2406@2|Bacteria,1G4NT@1117|Cyanobacteria	1117|Cyanobacteria	S	Belongs to the Dps family	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin
BYD2_k127_3286843_5	1157640.AQWO01000006_gene2625	1.446e-45	185.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria	201174|Actinobacteria	P	Belongs to the Fur family	furA	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
BYD2_k127_3286843_4	882082.SaccyDRAFT_2707	8.986e-55	202.0	COG0132@1|root,COG0132@2|Bacteria,2H6DY@201174|Actinobacteria	201174|Actinobacteria	H	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_26
BYD2_k127_3286843_0	1229780.BN381_350072	2.059e-119	396.0	COG0156@1|root,COG0156@2|Bacteria,2GISV@201174|Actinobacteria,3UXC7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class I and II	bioF	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0030312,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.3.1.47,6.2.1.14	ko:K00652,ko:K01906	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03209,R03210,R10124	RC00004,RC00014,RC00039,RC02725	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iNJ661.Rv1569	Aminotran_1_2
BYD2_k127_3293049_0	1313172.YM304_39270	0.0	1032.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2GJ7M@201174|Actinobacteria,4CMWD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
BYD2_k127_3309643_7	550540.Fbal_2965	8.82e-145	462.0	COG1180@1|root,COG1180@2|Bacteria,1NQC1@1224|Proteobacteria	1224|Proteobacteria	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
BYD2_k127_3309643_17	1121033.AUCF01000005_gene5291	3.312e-87	305.0	COG1355@1|root,COG2078@1|root,COG1355@2|Bacteria,COG2078@2|Bacteria,1MXK5@1224|Proteobacteria,2U13I@28211|Alphaproteobacteria,2JQVM@204441|Rhodospirillales	204441|Rhodospirillales	S	Belongs to the MEMO1 family	-	-	-	ko:K06990	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,Memo
BYD2_k127_3309643_6	471852.Tcur_0691	1.943e-159	531.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,4ENHY@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	fadD19_2	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_3309643_22	469383.Cwoe_3159	6.516e-58	211.0	COG2050@1|root,COG2050@2|Bacteria,2HMKZ@201174|Actinobacteria,4CSHW@84995|Rubrobacteria	84995|Rubrobacteria	Q	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
BYD2_k127_3309643_24	1382306.JNIM01000001_gene3962	5.027e-45	176.0	COG0652@1|root,COG0652@2|Bacteria,2G6RE@200795|Chloroflexi	200795|Chloroflexi	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802,ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
BYD2_k127_3309643_23	1463821.JOGR01000009_gene1850	3.126e-55	200.0	COG0243@1|root,COG0243@2|Bacteria,2GJ62@201174|Actinobacteria,4F07N@85014|Glycomycetales	201174|Actinobacteria	C	molybdopterin cofactor binding	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_3309643_10	1146883.BLASA_2833	9.899e-135	454.0	COG4608@1|root,COG4608@2|Bacteria,2H4BW@201174|Actinobacteria,4EUCP@85013|Frankiales	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
BYD2_k127_3309643_9	1120936.KB907209_gene1792	1.651e-136	457.0	COG0444@1|root,COG0444@2|Bacteria,2GIXV@201174|Actinobacteria	201174|Actinobacteria	EP	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031,ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,BPD_transp_1,oligo_HPY
BYD2_k127_3309643_21	1229780.BN381_50087	2.181e-69	246.0	COG1173@1|root,COG1173@2|Bacteria,2GJ9E@201174|Actinobacteria,3UWXI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
BYD2_k127_3309643_16	1229780.BN381_20133	1.1e-88	323.0	COG0601@1|root,COG0601@2|Bacteria,2GK0Z@201174|Actinobacteria,3UXS5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
BYD2_k127_3309643_3	1229780.BN381_20132	6.43e-166	540.0	COG0747@1|root,COG0747@2|Bacteria,2GJ4B@201174|Actinobacteria,3UXHK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Evidence 5 No homology to any previously reported sequences	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
BYD2_k127_3309643_14	1386089.N865_18735	1.219e-96	323.0	COG4122@1|root,COG4122@2|Bacteria,2GP7A@201174|Actinobacteria,4FIS4@85021|Intrasporangiaceae	201174|Actinobacteria	S	O-methyltransferase	mdmC	-	2.1.1.104	ko:K00588	ko00360,ko00940,ko00941,ko00945,ko01100,ko01110,map00360,map00940,map00941,map00945,map01100,map01110	M00039,M00350	R01942,R06578	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_3
BYD2_k127_3309643_19	1380393.JHVP01000012_gene2755	3.967e-82	282.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4ET1X@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_3309643_13	1394178.AWOO02000072_gene443	4.527e-101	338.0	COG1024@1|root,COG1024@2|Bacteria,2GKC4@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_3309643_5	479431.Namu_4908	3.871e-164	533.0	COG0405@1|root,COG0405@2|Bacteria,2GJYW@201174|Actinobacteria,4EUJP@85013|Frankiales	201174|Actinobacteria	E	Gamma-glutamyltranspeptidase	ywrD	-	2.3.2.2,3.4.19.13	ko:K00681	ko00430,ko00460,ko00480,ko01100,map00430,map00460,map00480,map01100	-	R00494,R01262,R01687,R03867,R03916,R03970,R03971,R04935	RC00064,RC00090,RC00096	ko00000,ko00001,ko01000,ko01002	-	-	-	G_glu_transpept
BYD2_k127_3309643_27	391589.RGAI101_4051	7.977e-20	105.0	COG1737@1|root,COG1737@2|Bacteria,1N3YS@1224|Proteobacteria,2TTJD@28211|Alphaproteobacteria,2P12G@2433|Roseobacter	28211|Alphaproteobacteria	K	COG1737 Transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
BYD2_k127_3309643_8	1382359.JIAL01000001_gene757	3.447e-140	461.0	COG1012@1|root,COG1012@2|Bacteria,3Y3V5@57723|Acidobacteria,2JIX2@204432|Acidobacteriia	204432|Acidobacteriia	C	Aldehyde dehydrogenase family	-	-	1.2.1.28	ko:K00141,ko:K22187	ko00040,ko00622,ko00623,ko00627,ko01100,ko01120,ko01220,map00040,map00622,map00623,map00627,map01100,map01120,map01220	M00537,M00538	R01293,R01419,R05289,R05663,R05664,R07667,R11768	RC00075,RC00080	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_3309643_12	338966.Ppro_0566	3.671e-111	399.0	COG0160@1|root,COG0160@2|Bacteria,1MWY6@1224|Proteobacteria,42MB7@68525|delta/epsilon subdivisions,2WJVU@28221|Deltaproteobacteria,43TEH@69541|Desulfuromonadales	28221|Deltaproteobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	2.6.1.19,2.6.1.22	ko:K00823,ko:K07250	ko00250,ko00280,ko00410,ko00640,ko00650,ko01100,ko01120,map00250,map00280,map00410,map00640,map00650,map01100,map01120	M00027	R00908,R01648,R04188	RC00006,RC00062,RC00160	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
BYD2_k127_3309643_0	518766.Rmar_1486	4.228e-234	756.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,4NE71@976|Bacteroidetes,1FINA@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Transketolase, pyrimidine binding domain	bfmBA	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
BYD2_k127_3309643_20	1894.JOER01000002_gene3502	7.444e-80	281.0	COG0584@1|root,COG0584@2|Bacteria,2GJ5W@201174|Actinobacteria	201174|Actinobacteria	C	glycerophosphoryl diester phosphodiesterase	glpQ2	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
BYD2_k127_3309643_2	471852.Tcur_0327	3.007e-171	550.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EHQQ@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
BYD2_k127_3309643_15	33876.JNXY01000009_gene8886	3.502e-95	343.0	COG0642@1|root,COG2205@2|Bacteria,2I2WT@201174|Actinobacteria,4DBZG@85008|Micromonosporales	201174|Actinobacteria	T	Nitrate and nitrite sensing	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_3309643_28	861299.J421_4333	6.524e-10	67.0	COG4911@1|root,COG4911@2|Bacteria	2|Bacteria	S	Uncharacterized conserved protein (DUF2203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2203
BYD2_k127_3309643_1	58123.JOFJ01000013_gene4952	8.499e-220	697.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4EIDS@85012|Streptosporangiales	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_3309643_25	1313172.YM304_25480	1.293e-40	160.0	COG2912@1|root,COG2912@2|Bacteria,2GMER@201174|Actinobacteria	201174|Actinobacteria	S	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	TPR_9,Transglut_core2
BYD2_k127_3309643_4	1313172.YM304_25510	6.156e-165	527.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4CNFE@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-CoA dehydrogenase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_3309643_11	1313172.YM304_20190	9.973e-133	438.0	COG0469@1|root,COG0469@2|Bacteria,2GJY8@201174|Actinobacteria,4CMXD@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Pyruvate kinase, barrel domain	-	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PK,PK_C
BYD2_k127_3309643_26	1283283.ATXA01000010_gene4499	9.501e-25	116.0	COG0596@1|root,COG0596@2|Bacteria	2|Bacteria	S	hydrolase activity, acting on ester bonds	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
BYD2_k127_3309643_18	1229780.BN381_50095	3.154e-84	299.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_3311184_1	1120936.KB907223_gene2415	4.749e-16	89.0	COG0501@1|root,COG0501@2|Bacteria,2H0IM@201174|Actinobacteria,4EKS4@85012|Streptosporangiales	201174|Actinobacteria	O	Peptidase family M48	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M48
BYD2_k127_3311184_0	68219.JNXI01000040_gene5462	2.006e-44	173.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
BYD2_k127_331600_4	164757.Mjls_5272	2.085e-18	89.0	COG0718@1|root,COG0718@2|Bacteria,2IRC4@201174|Actinobacteria,23A0U@1762|Mycobacteriaceae	201174|Actinobacteria	S	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	ybaB	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
BYD2_k127_331600_2	67267.JNXT01000099_gene1106	4.149e-93	308.0	COG0353@1|root,COG0353@2|Bacteria,2GJY0@201174|Actinobacteria	201174|Actinobacteria	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
BYD2_k127_331600_1	2074.JNYD01000004_gene4763	9.747e-101	362.0	COG2197@1|root,COG2197@2|Bacteria,2GNUY@201174|Actinobacteria,4DYXQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BYD2_k127_331600_5	1178540.BA70_09045	5.559e-12	71.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HM6Z@91061|Bacilli,1ZQQZ@1386|Bacillus	91061|Bacilli	F	Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B)	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
BYD2_k127_331600_3	1463854.JOHT01000003_gene6414	1.646e-31	126.0	COG1366@1|root,COG1366@2|Bacteria,2IHQG@201174|Actinobacteria	201174|Actinobacteria	T	Belongs to the anti-sigma-factor antagonist family	rsbV	GO:0003674,GO:0005488,GO:0005515,GO:0042802	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
BYD2_k127_331600_0	1229780.BN381_150129	2.507e-228	733.0	COG1205@1|root,COG1205@2|Bacteria,2GJJ6@201174|Actinobacteria,3UX61@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Domain of unknown function (DUF1998)	-	-	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
BYD2_k127_3322960_1	1429046.RR21198_5915	6.98e-121	398.0	COG4974@1|root,COG4974@2|Bacteria,2I9ZX@201174|Actinobacteria,4G3TF@85025|Nocardiaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
BYD2_k127_3322960_0	1027371.GOALK_070_00010	4.42e-132	440.0	COG4974@1|root,COG4974@2|Bacteria,2IBD6@201174|Actinobacteria,4GFSJ@85026|Gordoniaceae	201174|Actinobacteria	L	PFAM integrase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
BYD2_k127_3337495_2	471852.Tcur_2301	5.263e-105	347.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EH5C@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_3337495_0	1048339.KB913029_gene2528	5.94e-169	563.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_3337495_4	1229780.BN381_60026	4.299e-47	173.0	COG3871@1|root,COG3871@2|Bacteria,2IKYK@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Pyridoxamine 5'-phosphate	-	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0030312,GO:0031406,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0070967,GO:0071944,GO:0097159,GO:0097367,GO:1901363	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_3337495_5	1380390.JIAT01000010_gene4585	2.005e-38	154.0	2DMMQ@1|root,32SHK@2|Bacteria,2IHWW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3052
BYD2_k127_3337495_6	1229780.BN381_350092	4.404e-31	126.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	ksi	-	5.3.3.1	ko:K01822	ko00140,ko00984,ko01100,ko01120,map00140,map00984,map01100,map01120	M00107,M00110	R01837,R02216,R02499,R02840,R03327,R04163,R04678,R04849,R09955	RC00146,RC00762	ko00000,ko00001,ko00002,ko01000	-	-	-	SnoaL_2
BYD2_k127_3337495_1	518766.Rmar_2662	4.026e-146	475.0	COG1252@1|root,COG1252@2|Bacteria,4NE0H@976|Bacteroidetes,1FJ2X@1100069|Bacteroidetes Order II. Incertae sedis	976|Bacteroidetes	C	Pyridine nucleotide-disulphide oxidoreductase	ndh	-	1.6.99.3	ko:K03885	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
BYD2_k127_3337495_3	749414.SBI_06911	3.558e-91	318.0	COG4977@1|root,COG4977@2|Bacteria,2GIRA@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	adpA	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
BYD2_k127_3337495_7	345341.KUTG_09446	0.0002091	52.0	2E39G@1|root,32Y91@2|Bacteria,2GQNT@201174|Actinobacteria,4E705@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3363213_0	1313172.YM304_26020	4.979e-119	383.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
BYD2_k127_3363213_2	1229780.BN381_400042	3.817e-83	295.0	COG0638@1|root,COG0638@2|Bacteria,2GKZ1@201174|Actinobacteria,3UX82@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Proteasome subunit	prcA	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019773,GO:0019941,GO:0030163,GO:0030312,GO:0032991,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03432	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
BYD2_k127_3363213_1	1229780.BN381_400043	1.752e-108	358.0	COG0638@1|root,COG0638@2|Bacteria,2GJ60@201174|Actinobacteria,3UX89@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Proteasome subunit	prcB	GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369	3.4.25.1	ko:K03433	ko03050,map03050	M00342,M00343	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03051	-	-	-	Proteasome
BYD2_k127_3363213_4	463191.SSEG_10059	4.897e-16	83.0	2EFG7@1|root,3398W@2|Bacteria,2ID0P@201174|Actinobacteria	201174|Actinobacteria	L	Recombination endonuclease VII	-	-	-	-	-	-	-	-	-	-	-	-	Endonuclease_7
BYD2_k127_3363213_3	1313172.YM304_26060	8.376e-18	83.0	2E9C2@1|root,333JS@2|Bacteria,2HGHP@201174|Actinobacteria,4CNEV@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation	pup	-	-	ko:K13570	-	-	-	-	ko00000,ko04121	-	-	-	Pup
BYD2_k127_3367809_0	1184607.AUCHE_05_04270	0.0	1048.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG1149@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,COG1149@2|Bacteria,2I995@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
BYD2_k127_3367809_3	395961.Cyan7425_4370	4.839e-89	331.0	COG0167@1|root,COG0167@2|Bacteria,1G2B6@1117|Cyanobacteria,3KHF5@43988|Cyanothece	1117|Cyanobacteria	F	Catalyzes the conversion of dihydroorotate to orotate	-	-	1.3.98.1	ko:K00226	ko00240,ko01100,map00240,map01100	M00051	R01867	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
BYD2_k127_3367809_4	1525715.IX54_10105	7.253e-51	186.0	COG1247@1|root,COG1247@2|Bacteria,1RDNE@1224|Proteobacteria,2U9BP@28211|Alphaproteobacteria,2PWW6@265|Paracoccus	28211|Alphaproteobacteria	M	Acetyltransferase (GNAT) domain	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
BYD2_k127_3367809_7	390235.PputW619_3640	2.026e-25	115.0	COG0545@1|root,COG0545@2|Bacteria,1RDA1@1224|Proteobacteria,1S617@1236|Gammaproteobacteria,1YVJ5@136845|Pseudomonas putida group	1236|Gammaproteobacteria	G	Peptidyl-prolyl cis-trans isomerase	fbp	-	5.2.1.8	ko:K01802,ko:K03772	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	FKBP_C,Rhodanese
BYD2_k127_3367809_5	105420.BBPO01000060_gene3311	1.049e-31	130.0	COG1395@1|root,COG1395@2|Bacteria,2GVFR@201174|Actinobacteria,2NEHZ@228398|Streptacidiphilus	201174|Actinobacteria	K	Helix-turn-helix	bldD	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BYD2_k127_3367809_1	1229780.BN381_100129	2.522e-172	559.0	COG0527@1|root,COG0527@2|Bacteria,2GN0G@201174|Actinobacteria,3UWDX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	ACT domain	ask	GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
BYD2_k127_3367809_2	1120950.KB892720_gene1844	2.837e-160	511.0	COG0136@1|root,COG0136@2|Bacteria,2GJJ8@201174|Actinobacteria,4DNGU@85009|Propionibacteriales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate	asd	GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3708c	Semialdhyde_dh,Semialdhyde_dhC
BYD2_k127_3367809_6	367299.JOEE01000002_gene2532	3.081e-28	130.0	COG1694@1|root,COG1694@2|Bacteria,2ISAF@201174|Actinobacteria,4FJCG@85021|Intrasporangiaceae	201174|Actinobacteria	S	MazG nucleotide pyrophosphohydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	MazG
BYD2_k127_3367809_8	326424.FRAAL2698	7.344e-19	99.0	COG2518@1|root,COG2518@2|Bacteria,2GJ3I@201174|Actinobacteria	201174|Actinobacteria	O	PFAM Protein-L-isoaspartate(D-aspartate) O-methyltransferase	-	-	2.1.1.77	ko:K00573	-	-	-	-	ko00000,ko01000	-	-	-	Lant_dehydr_C,PCMT
BYD2_k127_3384126_9	632518.Calow_1478	6.421e-22	104.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,42GX3@68295|Thermoanaerobacterales	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
BYD2_k127_3384126_10	1229780.BN381_450089	7.061e-12	72.0	COG0255@1|root,COG0255@2|Bacteria,2IQ6V@201174|Actinobacteria,3UWTS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uL29 family	rpmC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
BYD2_k127_3384126_5	1229780.BN381_450090	1.622e-68	243.0	COG0197@1|root,COG0197@2|Bacteria,2IFEI@201174|Actinobacteria,3UWIH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
BYD2_k127_3384126_2	1229780.BN381_450091	8.108e-123	408.0	COG0092@1|root,COG0092@2|Bacteria,2GKF1@201174|Actinobacteria,3UW7M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
BYD2_k127_3384126_7	1313172.YM304_08300	1.045e-38	159.0	COG0091@1|root,COG0091@2|Bacteria,2IM3J@201174|Actinobacteria,4CNBP@84992|Acidimicrobiia	84992|Acidimicrobiia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
BYD2_k127_3384126_6	1121877.JQKF01000009_gene544	6.855e-44	175.0	COG0185@1|root,COG0185@2|Bacteria,2IKMS@201174|Actinobacteria,4CN5R@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
BYD2_k127_3384126_1	1229780.BN381_450094	1.079e-149	482.0	COG0090@1|root,COG0090@2|Bacteria,2GK7R@201174|Actinobacteria,3UWDY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
BYD2_k127_3384126_8	1313172.YM304_08270	1.541e-32	138.0	COG0089@1|root,COG0089@2|Bacteria,2IQ7V@201174|Actinobacteria,4CN84@84992|Acidimicrobiia	84992|Acidimicrobiia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
BYD2_k127_3384126_4	1229780.BN381_450096	5.107e-76	260.0	COG0088@1|root,COG0088@2|Bacteria,2GJYJ@201174|Actinobacteria,3UWGH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Forms part of the polypeptide exit tunnel	rplD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
BYD2_k127_3384126_3	1386969.AWTB01000007_gene2666	6.079e-84	284.0	COG0087@1|root,COG0087@2|Bacteria,2GJXT@201174|Actinobacteria,4GC8B@85026|Gordoniaceae	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
BYD2_k127_3384126_0	448385.sce7039	1.021e-185	604.0	COG0737@1|root,COG0737@2|Bacteria,1MX03@1224|Proteobacteria,42Q71@68525|delta/epsilon subdivisions,2WK8Q@28221|Deltaproteobacteria,2YX8I@29|Myxococcales	28221|Deltaproteobacteria	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5	ko:K01081	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
BYD2_k127_3406841_14	219305.MCAG_03981	2.659e-24	112.0	COG1670@1|root,COG1670@2|Bacteria,2GNYE@201174|Actinobacteria,4DA8Y@85008|Micromonosporales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
BYD2_k127_3406841_6	113395.AXAI01000011_gene6651	1.902e-76	264.0	COG0596@1|root,COG0596@2|Bacteria,1MWVN@1224|Proteobacteria,2TQVB@28211|Alphaproteobacteria,3JRID@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Epoxide hydrolase N terminus	-	-	3.3.2.9	ko:K01253,ko:K21159	ko00980,ko01059,ko04976,ko05204,map00980,map01059,map04976,map05204	-	R07013,R07014,R07027,R07071,R07072,R07082,R09410,R09417,R09443	RC01447,RC01728,RC01764,RC02528	ko00000,ko00001,ko01000,ko01002	-	-	-	EHN
BYD2_k127_3406841_1	1172185.KB911526_gene721	1.725e-210	674.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4FUM5@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BYD2_k127_3406841_15	591158.SSMG_06782	3.094e-24	109.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_3406841_10	1172185.KB911526_gene722	2.448e-53	197.0	2E4PM@1|root,32P93@2|Bacteria,2I85P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3406841_18	1304865.JAGF01000001_gene83	0.0001334	52.0	COG4319@1|root,COG4319@2|Bacteria,2IPRQ@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_3406841_8	562970.Btus_2387	1.661e-57	221.0	COG0508@1|root,COG0508@2|Bacteria,1TR5N@1239|Firmicutes,4HD9Z@91061|Bacilli,279NA@186823|Alicyclobacillaceae	91061|Bacilli	C	e3 binding domain	-	-	2.3.1.12	ko:K00627	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00209,R02569	RC00004,RC02742,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
BYD2_k127_3406841_2	1382304.JNIL01000001_gene1518	2.906e-152	487.0	COG0022@1|root,COG0022@2|Bacteria,1TP3J@1239|Firmicutes,4HAP6@91061|Bacilli	91061|Bacilli	C	COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit	-	-	-	ko:K21417	-	-	-	-	ko00000,ko01000	-	-	-	Transket_pyr,Transketolase_C
BYD2_k127_3406841_3	273068.TTE0688	3.903e-127	414.0	COG1071@1|root,COG1071@2|Bacteria,1TQDG@1239|Firmicutes,249HX@186801|Clostridia,42HZK@68295|Thermoanaerobacterales	186801|Clostridia	C	1-deoxy-D-xylulose-5-phosphate synthase	-	-	1.2.4.1	ko:K00161,ko:K21416	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko04066,ko04922,ko05230,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200,map04066,map04922,map05230	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh
BYD2_k127_3406841_9	309801.trd_1495	1.166e-54	207.0	COG0061@1|root,COG3199@1|root,COG0061@2|Bacteria,COG3199@2|Bacteria,2G8JA@200795|Chloroflexi,27YB7@189775|Thermomicrobia	189775|Thermomicrobia	G	ATP-NAD kinase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_kinase
BYD2_k127_3406841_0	1032480.MLP_14060	1.042e-240	806.0	COG1412@1|root,COG3209@1|root,COG1412@2|Bacteria,COG3209@2|Bacteria,2GMBB@201174|Actinobacteria,4DSV8@85009|Propionibacteriales	201174|Actinobacteria	M	RHS Repeat	-	-	-	-	-	-	-	-	-	-	-	-	PT-HINT,RHS_repeat
BYD2_k127_3406841_17	512565.AMIS_48940	5.952e-06	54.0	COG3209@1|root,COG3209@2|Bacteria	2|Bacteria	M	self proteolysis	-	-	-	-	-	-	-	-	-	-	-	-	Calx-beta,Flg_new,Laminin_G_3,PA14,PT-HINT,RHS_repeat
BYD2_k127_3406841_13	1206729.BAFZ01000041_gene4626	4.078e-27	128.0	2BNH2@1|root,32H59@2|Bacteria,2HHBE@201174|Actinobacteria,4FX35@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3406841_7	365528.KB891269_gene5983	2.043e-72	253.0	COG3427@1|root,COG3427@2|Bacteria,2GKTQ@201174|Actinobacteria,4ESNJ@85013|Frankiales	201174|Actinobacteria	S	carbon monoxide dehydrogenase subunit G	-	-	-	ko:K09386	-	-	-	-	ko00000	-	-	-	COXG
BYD2_k127_3406841_11	1313172.YM304_33410	3.018e-42	161.0	COG2068@1|root,COG2068@2|Bacteria,2HG9S@201174|Actinobacteria,4CN88@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MobA-like NTP transferase domain	-	-	1.1.1.328,2.7.7.76	ko:K07141,ko:K19190	ko00760,ko00790,ko01120,map00760,map00790,map01120	-	R10131,R10132,R11582	RC03053	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
BYD2_k127_3406841_4	1306174.JODP01000006_gene3139	4.378e-98	331.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
BYD2_k127_3406841_12	1306174.JODP01000006_gene3139	6.624e-35	136.0	COG1975@1|root,COG1975@2|Bacteria,2GIZS@201174|Actinobacteria	201174|Actinobacteria	O	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
BYD2_k127_3406841_5	1265310.CCBD010000015_gene3496	7.461e-91	306.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,2359Z@1762|Mycobacteriaceae	201174|Actinobacteria	S	VWA containing CoxE family protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
BYD2_k127_3407609_0	1157638.KB892191_gene5137	5.364e-114	382.0	COG1819@1|root,COG1819@2|Bacteria,2GJMF@201174|Actinobacteria	201174|Actinobacteria	CG	glycosyl	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
BYD2_k127_3407609_1	463191.SSEG_01292	1.163e-108	360.0	COG1024@1|root,COG1024@2|Bacteria,2HEIS@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_3407609_4	1121272.KB903258_gene5360	3.867e-24	110.0	COG1595@1|root,COG1595@2|Bacteria,2GWFT@201174|Actinobacteria,4DJEK@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_3407609_3	298653.Franean1_4281	2.738e-26	125.0	COG3507@1|root,COG3507@2|Bacteria,2HTZY@201174|Actinobacteria,4EVX3@85013|Frankiales	201174|Actinobacteria	G	Glycosyl hydrolases family 43	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
BYD2_k127_3407609_2	357808.RoseRS_0965	4.885e-42	157.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,376D2@32061|Chloroflexia	32061|Chloroflexia	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
BYD2_k127_3416212_11	1380356.JNIK01000017_gene2805	1.389e-32	132.0	COG4319@1|root,COG4319@2|Bacteria,2IBWU@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
BYD2_k127_3416212_3	1123320.KB889585_gene1767	1.431e-87	308.0	COG2141@1|root,COG2141@2|Bacteria,2I9FZ@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_3416212_10	1313172.YM304_01020	1.859e-47	177.0	COG4803@1|root,COG4803@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1269
BYD2_k127_3416212_6	298655.KI912266_gene3382	4.674e-59	214.0	COG1296@1|root,COG1296@2|Bacteria,2IKHA@201174|Actinobacteria	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
BYD2_k127_3416212_1	1120949.KB903339_gene8068	1.487e-108	365.0	COG0644@1|root,COG0644@2|Bacteria,2GJDF@201174|Actinobacteria	201174|Actinobacteria	C	Tryptophan halogenase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
BYD2_k127_3416212_0	1298863.AUEP01000011_gene627	1.644e-125	434.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2GM4U@201174|Actinobacteria,4DUTC@85009|Propionibacteriales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
BYD2_k127_3416212_12	33876.JNXY01000052_gene6395	3.819e-28	133.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,4DMHP@85008|Micromonosporales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
BYD2_k127_3416212_8	1001240.GY21_09500	2.321e-53	190.0	COG0346@1|root,COG0346@2|Bacteria,2GQZ9@201174|Actinobacteria,4FT4H@85023|Microbacteriaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_3416212_9	1283283.ATXA01000001_gene348	4.471e-49	184.0	COG2030@1|root,COG2030@2|Bacteria,2IK2Z@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
BYD2_k127_3416212_2	1120949.KB903339_gene8070	4.742e-102	368.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I75H@201174|Actinobacteria	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_3416212_7	1449347.JQLN01000004_gene6330	7.387e-57	209.0	COG2755@1|root,COG2755@2|Bacteria,2IFV1@201174|Actinobacteria	201174|Actinobacteria	E	lipolytic protein G-D-S-L family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
BYD2_k127_3416212_4	1229780.BN381_330062	2.645e-85	304.0	COG4690@1|root,COG4690@2|Bacteria	2|Bacteria	E	dipeptidase activity	-	-	-	ko:K14358	-	-	-	-	ko00000,ko01002	-	-	-	AAT,Peptidase_C69
BYD2_k127_3416212_5	1121946.AUAX01000019_gene7792	4.717e-82	281.0	COG1231@1|root,COG1231@2|Bacteria,2GK23@201174|Actinobacteria,4DD66@85008|Micromonosporales	201174|Actinobacteria	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
BYD2_k127_3434570_15	404589.Anae109_0053	2.835e-22	105.0	COG0697@1|root,COG0697@2|Bacteria,1N024@1224|Proteobacteria,42NW9@68525|delta/epsilon subdivisions,2WJEJ@28221|Deltaproteobacteria,2YXIG@29|Myxococcales	28221|Deltaproteobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
BYD2_k127_3434570_14	1229780.BN381_10085	3.63e-28	124.0	COG1011@1|root,COG1011@2|Bacteria,2HP8I@201174|Actinobacteria,3UWYW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
BYD2_k127_3434570_0	1313172.YM304_38270	8.116e-230	734.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,2GK2C@201174|Actinobacteria,4CMPV@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
BYD2_k127_3434570_2	44060.JODL01000010_gene1660	3.065e-166	578.0	COG1391@1|root,COG1391@2|Bacteria,2GJ91@201174|Actinobacteria	201174|Actinobacteria	OT	Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell	glnE	GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698	2.7.7.42,2.7.7.89	ko:K00982	-	-	-	-	ko00000,ko01000	-	-	-	GlnD_UR_UTase,GlnE
BYD2_k127_3434570_4	1347086.CCBA010000003_gene3907	5.122e-95	321.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,4HB91@91061|Bacilli,1ZB27@1386|Bacillus	91061|Bacilli	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
BYD2_k127_3434570_1	512565.AMIS_58670	5.487e-187	601.0	COG2234@1|root,COG2234@2|Bacteria,2HVJR@201174|Actinobacteria,4DHBB@85008|Micromonosporales	201174|Actinobacteria	S	PA domain	-	-	-	-	-	-	-	-	-	-	-	-	PA,Peptidase_M28
BYD2_k127_3434570_7	1313172.YM304_41590	1.886e-66	233.0	COG0218@1|root,COG0218@2|Bacteria	2|Bacteria	D	Necessary for normal cell division and for the maintenance of normal septation	engB	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
BYD2_k127_3434570_13	234267.Acid_2841	8.989e-30	131.0	COG1476@1|root,COG1910@1|root,COG1476@2|Bacteria,COG1910@2|Bacteria	2|Bacteria	P	PBP superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,PBP_like
BYD2_k127_3434570_8	326427.Cagg_1370	3.854e-58	227.0	COG0725@1|root,COG0725@2|Bacteria,2G6J6@200795|Chloroflexi,376NT@32061|Chloroflexia	32061|Chloroflexia	P	TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein	-	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	SBP_bac_11
BYD2_k127_3434570_9	1452718.JBOY01000092_gene2704	2.576e-57	208.0	COG4149@1|root,COG4149@2|Bacteria,1MUXR@1224|Proteobacteria,1RRDV@1236|Gammaproteobacteria	1236|Gammaproteobacteria	P	ABC-type molybdate transport system, permease component	modB	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iECO103_1326.ECO103_0752	BPD_transp_1
BYD2_k127_3434570_11	292459.STH998	3.632e-40	166.0	COG3842@1|root,COG3842@2|Bacteria,1TQ18@1239|Firmicutes,24AEK@186801|Clostridia	186801|Clostridia	E	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
BYD2_k127_3434570_5	1240349.ANGC01000001_gene2575	3.034e-79	295.0	COG0500@1|root,COG2226@2|Bacteria,2GM2N@201174|Actinobacteria	201174|Actinobacteria	Q	PFAM Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_3434570_3	1032480.MLP_17680	3.099e-116	395.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,4DQF1@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,TPR_19
BYD2_k127_3434570_12	1996.JOFO01000001_gene3942	1.498e-39	153.0	COG2002@1|root,COG2002@2|Bacteria,2I3FX@201174|Actinobacteria	201174|Actinobacteria	K	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905
BYD2_k127_3434570_10	1206741.BAFX01000199_gene2986	1.817e-49	181.0	COG0500@1|root,COG0500@2|Bacteria,2GM5T@201174|Actinobacteria,4FUHD@85025|Nocardiaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_3434570_16	1156844.KB891797_gene5514	1.594e-17	93.0	COG0346@1|root,COG0346@2|Bacteria,2IFMD@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3434570_6	1280950.HJO_16100	1.848e-67	239.0	COG1024@1|root,COG1024@2|Bacteria,1MVQN@1224|Proteobacteria,2U31Y@28211|Alphaproteobacteria	1224|Proteobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_3434570_17	1449353.JQMQ01000005_gene1429	2.172e-08	62.0	COG1946@1|root,COG1946@2|Bacteria,2GJ1B@201174|Actinobacteria,2NEH9@228398|Streptacidiphilus	201174|Actinobacteria	I	Acyl-CoA thioesterase	tesB	-	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
BYD2_k127_3533030_16	479433.Caci_7398	1.424e-39	153.0	COG2864@1|root,COG2864@2|Bacteria,2GNYK@201174|Actinobacteria	201174|Actinobacteria	C	Prokaryotic cytochrome b561	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
BYD2_k127_3533030_21	882086.SacxiDRAFT_1324	8.054e-10	63.0	2E3M2@1|root,32YJA@2|Bacteria,2GQQW@201174|Actinobacteria,4E6SK@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF3107)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3107
BYD2_k127_3533030_6	1229780.BN381_310065	1.649e-113	374.0	COG0003@1|root,COG0003@2|Bacteria,2GJ0J@201174|Actinobacteria	201174|Actinobacteria	D	Pfam Anion-transporting ATPase	arsA_2	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
BYD2_k127_3533030_1	1229780.BN381_310066	6.688e-155	497.0	COG0003@1|root,COG0003@2|Bacteria,2GJYN@201174|Actinobacteria	201174|Actinobacteria	D	anion-transporting ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ArsA_ATPase
BYD2_k127_3533030_2	1313172.YM304_09850	5.112e-139	469.0	COG3920@1|root,COG3920@2|Bacteria,2GKMP@201174|Actinobacteria,4CMRV@84992|Acidimicrobiia	84992|Acidimicrobiia	T	Histidine kinase	-	-	2.7.13.3	ko:K00936	-	M00839	-	-	ko00000,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,H_kinase_N,HisKA_2
BYD2_k127_3533030_17	1229780.BN381_310068	3.072e-39	148.0	2DMIE@1|root,32RSG@2|Bacteria,2IQCG@201174|Actinobacteria,3UWR8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	whiB	GO:0000302,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0010035,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0015035,GO:0015036,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0042221,GO:0042493,GO:0045892,GO:0045934,GO:0047134,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
BYD2_k127_3533030_15	1313172.YM304_09890	1.015e-43	173.0	COG0584@1|root,COG0584@2|Bacteria	2|Bacteria	C	glycerophosphodiester phosphodiesterase activity	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
BYD2_k127_3533030_8	1313172.YM304_09900	3.164e-91	312.0	COG1597@1|root,COG1597@2|Bacteria,2HH1A@201174|Actinobacteria,4CP1H@84992|Acidimicrobiia	2|Bacteria	G	Diacylglycerol kinase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
BYD2_k127_3533030_14	649831.L083_2714	1.16e-49	186.0	COG0745@1|root,COG0745@2|Bacteria,2GMZK@201174|Actinobacteria	201174|Actinobacteria	T	regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_3533030_7	1386089.N865_18020	3.941e-112	389.0	2CA6S@1|root,2Z9P6@2|Bacteria,2IAT3@201174|Actinobacteria,4FFFX@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3533030_18	1380356.JNIK01000011_gene1782	7.338e-38	151.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_3533030_10	1121877.JQKF01000016_gene169	1.102e-80	288.0	COG2086@1|root,COG2086@2|Bacteria,2GKV6@201174|Actinobacteria,4CMXI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Electron transfer flavoprotein domain	-	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
BYD2_k127_3533030_5	1229780.BN381_310072	3.143e-117	399.0	COG2025@1|root,COG2025@2|Bacteria,2GJWH@201174|Actinobacteria,3UWMR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Electron transfer flavoprotein FAD-binding domain	etfA	-	-	ko:K03522	-	-	-	-	ko00000,ko04147	-	-	-	ETF,ETF_alpha
BYD2_k127_3533030_11	649638.Trad_1636	1.935e-73	259.0	COG2321@1|root,COG2321@2|Bacteria,1WMCA@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Putative neutral zinc metallopeptidase	-	-	-	ko:K07054	-	-	-	-	ko00000	-	-	-	Zn_peptidase
BYD2_k127_3533030_4	35754.JNYJ01000044_gene4355	1.62e-127	450.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4DHDF@85008|Micromonosporales	201174|Actinobacteria	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
BYD2_k127_3533030_13	396014.BF93_11205	1.797e-66	239.0	COG5032@1|root,COG5032@2|Bacteria,2GME7@201174|Actinobacteria,4FD4E@85020|Dermabacteraceae	201174|Actinobacteria	BDLTU	Phosphatidylinositol	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3533030_20	1121877.JQKF01000069_gene1260	3.346e-26	119.0	298YA@1|root,2ZW25@2|Bacteria,2GIYI@201174|Actinobacteria,4CN9I@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3090)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3090
BYD2_k127_3533030_12	136273.GY22_04980	1.702e-69	244.0	COG0406@1|root,COG0406@2|Bacteria,2GK8N@201174|Actinobacteria,1W9CE@1268|Micrococcaceae	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
BYD2_k127_3533030_9	1229780.BN381_310076	2.803e-83	297.0	COG1573@1|root,COG1573@2|Bacteria,2GK1I@201174|Actinobacteria,3UXAR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Uracil DNA glycosylase superfamily	udgB	GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360	3.2.2.27	ko:K21929	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
BYD2_k127_3533030_3	391037.Sare_1636	1.816e-129	441.0	COG0443@1|root,COG3266@1|root,COG0443@2|Bacteria,COG3266@2|Bacteria,2GNTE@201174|Actinobacteria,4DM1N@85008|Micromonosporales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
BYD2_k127_3533030_0	1229780.BN381_310078	8.986e-196	619.0	COG1035@1|root,COG1146@1|root,COG1035@2|Bacteria,COG1146@2|Bacteria,2GRHK@201174|Actinobacteria	201174|Actinobacteria	C	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term	-	-	1.12.98.1	ko:K00441	ko00680,ko01100,ko01120,map00680,map01100,map01120	-	R03025	RC02628	ko00000,ko00001,ko01000	-	-	-	Fer4_9,FrhB_FdhB_C,FrhB_FdhB_N
BYD2_k127_3533030_19	1122611.KB903954_gene5666	5.645e-30	138.0	COG1316@1|root,COG1316@2|Bacteria,2GJM3@201174|Actinobacteria,4EGTU@85012|Streptosporangiales	201174|Actinobacteria	K	LytR cell envelope-related transcriptional attenuator	yvhJ	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
BYD2_k127_3552101_0	204669.Acid345_0465	0.0	1172.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria,2JHJH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
BYD2_k127_3555661_4	1229780.BN381_210103	7.303e-40	171.0	COG0560@1|root,COG0560@2|Bacteria,2GTHF@201174|Actinobacteria	201174|Actinobacteria	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.27	ko:K18697	ko00564,map00564	-	R02029	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD
BYD2_k127_3555661_1	58123.JOFJ01000001_gene3202	9.991e-86	308.0	COG1090@1|root,COG1090@2|Bacteria,2GJS0@201174|Actinobacteria,4EFV0@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF1731)	-	-	-	ko:K07071	-	-	-	-	ko00000	-	-	-	DUF1731,Epimerase
BYD2_k127_3555661_6	106370.Francci3_0070	1.508e-32	132.0	COG1970@1|root,COG1970@2|Bacteria,2IQDN@201174|Actinobacteria,4ET97@85013|Frankiales	201174|Actinobacteria	M	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell	mscL	-	-	ko:K03282	-	-	-	-	ko00000,ko02000	1.A.22.1	-	-	MscL
BYD2_k127_3555661_3	391625.PPSIR1_33806	5.664e-58	209.0	COG2193@1|root,COG2193@2|Bacteria,1RCW7@1224|Proteobacteria,42SK2@68525|delta/epsilon subdivisions,2WPB3@28221|Deltaproteobacteria,2Z0CU@29|Myxococcales	28221|Deltaproteobacteria	P	Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex	bfr	GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771	1.16.3.1	ko:K03594	ko00860,map00860	-	R00078	RC02758	ko00000,ko00001,ko01000	-	-	-	Ferritin
BYD2_k127_3555661_7	2074.JNYD01000001_gene6165	2.654e-11	68.0	COG1251@1|root,COG1251@2|Bacteria	2|Bacteria	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	bfd	-	-	ko:K00360,ko:K02192	ko00910,ko01120,map00910,map01120	M00531	R00798	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,Pyr_redox_2
BYD2_k127_3555661_2	649831.L083_3320	2.566e-78	282.0	COG1680@1|root,COG1680@2|Bacteria,2I2WV@201174|Actinobacteria	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_3555661_0	1229780.BN381_210107	2.014e-183	611.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,3UWCV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
BYD2_k127_3555661_5	1313172.YM304_29650	3.232e-36	141.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
BYD2_k127_3567994_5	644548.SCNU_07498	1.299e-79	270.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4GAKY@85026|Gordoniaceae	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_3567994_7	1229203.KI301992_gene1421	3.843e-48	177.0	COG1393@1|root,COG1393@2|Bacteria,2HZAU@201174|Actinobacteria,3UXRD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	ArsC family	-	-	-	-	-	-	-	-	-	-	-	-	ArsC
BYD2_k127_3567994_1	937777.Deipe_0633	3.49e-143	466.0	COG0039@1|root,COG0039@2|Bacteria,1WJHY@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	C	Catalyzes the reversible oxidation of malate to oxaloacetate	mdh	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564	1.1.1.37	ko:K00024	ko00020,ko00270,ko00620,ko00630,ko00680,ko00710,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00270,map00620,map00630,map00680,map00710,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00012,M00168,M00173,M00346,M00374,M00620,M00740	R00342,R07136	RC00031	ko00000,ko00001,ko00002,ko01000	-	-	-	Ldh_1_C,Ldh_1_N
BYD2_k127_3567994_4	369723.Strop_2135	8.994e-92	328.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
BYD2_k127_3567994_2	1313172.YM304_07320	7.072e-103	345.0	COG0266@1|root,COG0266@2|Bacteria,2GKAM@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the FPG family	mutM1	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
BYD2_k127_3567994_8	1313172.YM304_07330	2.643e-14	80.0	COG3255@1|root,COG3255@2|Bacteria,2IGUY@201174|Actinobacteria	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
BYD2_k127_3567994_3	1229780.BN381_130073	2.408e-96	325.0	COG3173@1|root,COG3173@2|Bacteria,2GMZQ@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	EcKinase
BYD2_k127_3567994_6	419610.Mext_0105	6.022e-51	188.0	COG0586@1|root,COG0586@2|Bacteria,1MX4M@1224|Proteobacteria,2U6ZF@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane-associated protein	-	-	3.1.3.1	ko:K01077	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	SNARE_assoc
BYD2_k127_3567994_0	1146883.BLASA_0347	5.039e-160	523.0	COG1086@1|root,COG1086@2|Bacteria,2GIXM@201174|Actinobacteria,4ERU6@85013|Frankiales	201174|Actinobacteria	GM	Polysaccharide biosynthesis protein	capD	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_binding_3,Polysacc_synt_2
BYD2_k127_3568952_7	58123.JOFJ01000012_gene5386	3.236e-41	153.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria,4EHW2@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_3568952_6	526225.Gobs_3702	6.404e-43	166.0	COG1917@1|root,COG1917@2|Bacteria,2IIQY@201174|Actinobacteria	201174|Actinobacteria	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_3568952_4	745310.G432_06970	1.802e-51	194.0	COG0824@1|root,COG0824@2|Bacteria,1R6A6@1224|Proteobacteria,2TU6J@28211|Alphaproteobacteria,2K9RB@204457|Sphingomonadales	204457|Sphingomonadales	S	Thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3568952_1	526225.Gobs_2306	1.865e-58	211.0	COG1266@1|root,COG1266@2|Bacteria,2GKRA@201174|Actinobacteria,4EVQR@85013|Frankiales	201174|Actinobacteria	S	Abortive infection protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
BYD2_k127_3568952_2	1229780.BN381_310040	1.02e-53	196.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,3UWW4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_3568952_10	935866.JAER01000037_gene578	1.455e-08	66.0	COG2013@1|root,COG2013@2|Bacteria,2GSX6@201174|Actinobacteria,4DPJ8@85009|Propionibacteriales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF2510
BYD2_k127_3568952_0	1313172.YM304_09570	5.911e-60	216.0	COG1024@1|root,COG1024@2|Bacteria,2GJG7@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA6	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_3568952_8	269800.Tfu_2084	2.495e-25	118.0	2EGCD@1|root,33A46@2|Bacteria,2I14B@201174|Actinobacteria,4EKUH@85012|Streptosporangiales	201174|Actinobacteria	S	Septum formation	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
BYD2_k127_3568952_11	2045.KR76_07500	6.127e-06	58.0	COG2013@1|root,COG2013@2|Bacteria,2GSX6@201174|Actinobacteria,4DPJ8@85009|Propionibacteriales	201174|Actinobacteria	S	Mitochondrial biogenesis AIM24	-	-	-	-	-	-	-	-	-	-	-	-	AIM24,DUF2510
BYD2_k127_3568952_3	1229780.BN381_310048	4.892e-52	197.0	COG3764@1|root,COG3764@2|Bacteria,2GKT6@201174|Actinobacteria,3UXMS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 5 No homology to any previously reported sequences	srtB	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
BYD2_k127_3568952_5	1229780.BN381_310049	1.121e-48	178.0	COG1131@1|root,COG1131@2|Bacteria,2IRXJ@201174|Actinobacteria	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	3.6.3.41	ko:K02193	ko02010,map02010	M00259	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.107	-	-	ABC_tran
BYD2_k127_3569935_0	63737.Npun_R0280	7.193e-142	469.0	COG3540@1|root,COG3540@2|Bacteria,1G0C9@1117|Cyanobacteria,1HKPP@1161|Nostocales	1117|Cyanobacteria	P	PhoD-like phosphatase, N-terminal domain	phoD	-	3.1.3.1	ko:K01113	ko00790,ko01100,ko02020,map00790,map01100,map02020	M00126	R04620	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PhoD,PhoD_N
BYD2_k127_3569935_1	2002.JOEQ01000013_gene5478	2.339e-58	217.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
BYD2_k127_3585534_0	1229780.BN381_80149	6.631e-148	482.0	COG0008@1|root,COG0008@2|Bacteria,2GJJS@201174|Actinobacteria,3UW9W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
BYD2_k127_3585534_6	1313172.YM304_13340	6.121e-44	175.0	COG1434@1|root,COG1434@2|Bacteria,2I2NF@201174|Actinobacteria	201174|Actinobacteria	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
BYD2_k127_3585534_8	981369.JQMJ01000004_gene246	2.121e-36	154.0	COG2267@1|root,COG2267@2|Bacteria,2II1K@201174|Actinobacteria,2NIRM@228398|Streptacidiphilus	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Glyoxalase
BYD2_k127_3585534_4	472759.Nhal_3033	5.591e-53	196.0	COG0346@1|root,COG0346@2|Bacteria,1RI3Q@1224|Proteobacteria,1S6F6@1236|Gammaproteobacteria,1X126@135613|Chromatiales	135613|Chromatiales	C	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_3585534_5	208444.JNYY01000006_gene6874	6.879e-52	186.0	COG3801@1|root,COG3801@2|Bacteria,2IQGZ@201174|Actinobacteria,4E52D@85010|Pseudonocardiales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_3585534_1	1313172.YM304_36470	1.781e-100	332.0	COG0692@1|root,COG0692@2|Bacteria,2GJ9Z@201174|Actinobacteria	201174|Actinobacteria	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
BYD2_k127_3585534_3	1120936.KB907226_gene2797	3.038e-68	241.0	COG4689@1|root,COG4689@2|Bacteria,2GJWN@201174|Actinobacteria,4EI2S@85012|Streptosporangiales	201174|Actinobacteria	Q	Acetoacetate decarboxylase (ADC)	-	-	-	-	-	-	-	-	-	-	-	-	ADC
BYD2_k127_3585534_2	105425.BBPL01000002_gene6534	2.483e-82	284.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,2NH95@228398|Streptacidiphilus	201174|Actinobacteria	L	Phage integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_3585534_7	1122609.AUGT01000005_gene1816	5.68e-40	150.0	COG2963@1|root,COG2963@2|Bacteria,2IM4Y@201174|Actinobacteria,4DSTP@85009|Propionibacteriales	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07483	-	-	-	-	ko00000	-	-	-	HTH_Tnp_1
BYD2_k127_3585534_11	1122622.ATWJ01000002_gene713	0.0008535	47.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4FEGQ@85021|Intrasporangiaceae	201174|Actinobacteria	L	COG2801 Transposase and inactivated derivatives	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,rve,rve_2,rve_3
BYD2_k127_3585534_9	136273.GY22_16965	4.273e-27	111.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,1W7H6@1268|Micrococcaceae	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_2,rve_3
BYD2_k127_361284_2	350054.Mflv_2468	1.026e-21	95.0	COG1018@1|root,COG1018@2|Bacteria,2GKGS@201174|Actinobacteria,235CQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Fer2,NAD_binding_1
BYD2_k127_361284_1	1206726.BAFV01000122_gene6146	9.727e-56	201.0	COG4319@1|root,COG4319@2|Bacteria,2IFX9@201174|Actinobacteria,4G0HN@85025|Nocardiaceae	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
BYD2_k127_361284_0	47839.CCAU010000017_gene3850	3.047e-139	451.0	COG1960@1|root,COG1960@2|Bacteria,2GKYN@201174|Actinobacteria,234GS@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_361284_3	1206731.BAGB01000166_gene843	0.0003638	53.0	COG1960@1|root,COG1960@2|Bacteria,2GM6Q@201174|Actinobacteria,4FX04@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
BYD2_k127_3638345_1	1313172.YM304_12700	2.442e-194	621.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,4CMQA@84992|Acidimicrobiia	84992|Acidimicrobiia	EH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
BYD2_k127_3638345_8	477641.MODMU_1067	2.388e-82	285.0	COG0122@1|root,COG2169@1|root,COG0122@2|Bacteria,COG2169@2|Bacteria,2GITG@201174|Actinobacteria,4ES83@85013|Frankiales	201174|Actinobacteria	K	helix-turn-helix- domain containing protein AraC type	ada	-	2.1.1.63,3.2.2.21	ko:K00567,ko:K13529	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,HTH_18,HhH-GPD
BYD2_k127_3638345_0	2074.JNYD01000035_gene6708	4.116e-245	785.0	COG1506@1|root,COG1506@2|Bacteria,2GNG5@201174|Actinobacteria,4DXIE@85010|Pseudonocardiales	201174|Actinobacteria	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
BYD2_k127_3638345_11	452652.KSE_04175	8.596e-42	171.0	COG3170@1|root,COG3170@2|Bacteria,2H5I1@201174|Actinobacteria,2M58V@2063|Kitasatospora	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3638345_2	1394178.AWOO02000003_gene2793	4.323e-193	612.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4EGQ9@85012|Streptosporangiales	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	-	2.6.1.1	ko:K00812	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
BYD2_k127_3638345_3	1229780.BN381_80054	1.294e-154	497.0	COG1932@1|root,COG1932@2|Bacteria,2GKYK@201174|Actinobacteria,3UWA9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005886,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0040007,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
BYD2_k127_3638345_6	1869.MB27_33290	2.596e-107	357.0	COG2141@1|root,COG2141@2|Bacteria,2HGTQ@201174|Actinobacteria,4DENR@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_3638345_15	1120948.KB903231_gene4715	0.0002998	54.0	2BRWA@1|root,32KWK@2|Bacteria	1120948.KB903231_gene4715|-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3638345_12	1122622.ATWJ01000002_gene795	2.192e-29	123.0	COG1733@1|root,COG1733@2|Bacteria,2IRHS@201174|Actinobacteria,4FI6I@85021|Intrasporangiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
BYD2_k127_3638345_10	1229780.BN381_130137	3.388e-75	269.0	COG0265@1|root,COG0265@2|Bacteria,2INQH@201174|Actinobacteria	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
BYD2_k127_3638345_7	1121946.AUAX01000012_gene6615	1.573e-89	308.0	COG0265@1|root,COG0265@2|Bacteria,2GNZT@201174|Actinobacteria,4DCKP@85008|Micromonosporales	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	-	-	-	-	-	-	-	-	-	-	-	-	PDZ_2,Trypsin_2
BYD2_k127_3638345_14	1089544.KB912942_gene490	2.371e-12	76.0	COG3324@1|root,COG3324@2|Bacteria,2IRUY@201174|Actinobacteria,4E63A@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Glyoxalase Bleomycin resistance protein Dioxygenase superfamily	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
BYD2_k127_3638345_13	1201293.AKXQ01000005_gene139	1.389e-12	77.0	2EGVV@1|root,33AN3@2|Bacteria,1NJ5K@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3638345_9	436229.JOEH01000004_gene49	1.742e-81	283.0	COG1595@1|root,COG1595@2|Bacteria,2H8GI@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_3638345_5	1500306.JQLA01000030_gene3930	4.954e-135	436.0	COG0596@1|root,COG0596@2|Bacteria,1R4ZX@1224|Proteobacteria,2TU6R@28211|Alphaproteobacteria,4BAEH@82115|Rhizobiaceae	28211|Alphaproteobacteria	S	alpha/beta hydrolase fold	-	-	3.8.1.5	ko:K01563	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05284,R05367,R05368,R05369,R05370,R07669,R07670	RC01317,RC01340,RC01341,RC02013	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_3638345_4	1429046.RR21198_1177	2.359e-142	463.0	COG1752@1|root,COG1752@2|Bacteria,2HJ6N@201174|Actinobacteria,4G5HY@85025|Nocardiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_3674049_3	1313172.YM304_05230	3.446e-125	412.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria	201174|Actinobacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_3674049_0	2074.JNYD01000001_gene6179	3.011e-192	606.0	COG2141@1|root,COG2141@2|Bacteria,2GITK@201174|Actinobacteria,4E091@85010|Pseudonocardiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	limB	-	1.14.13.107	ko:K14733	ko00903,map00903	-	R06398,R09385,R09389,R09393	RC01506	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
BYD2_k127_3674049_2	2074.JNYD01000012_gene450	1.196e-137	446.0	COG2267@1|root,COG2267@2|Bacteria,2I2KD@201174|Actinobacteria,4EF63@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	ephA	GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006725,GO:0006793,GO:0006796,GO:0006950,GO:0006952,GO:0006954,GO:0007600,GO:0008015,GO:0008150,GO:0008152,GO:0008217,GO:0009056,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015643,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0018742,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019439,GO:0019752,GO:0030258,GO:0032501,GO:0032787,GO:0033559,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045777,GO:0046272,GO:0046483,GO:0046839,GO:0046872,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050877,GO:0050896,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090181,GO:0097176,GO:1900673,GO:1901360,GO:1901361,GO:1901575	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_3674049_8	1313172.YM304_02290	1.328e-78	283.0	COG0654@1|root,COG0654@2|Bacteria,2I901@201174|Actinobacteria	201174|Actinobacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,NAD_binding_8,Trp_halogenase
BYD2_k127_3674049_10	2074.JNYD01000001_gene6181	8.477e-51	187.0	COG1309@1|root,COG1309@2|Bacteria,2GNGT@201174|Actinobacteria,4EEZU@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_3674049_5	640511.BC1002_6195	3.159e-83	284.0	COG3485@1|root,COG3485@2|Bacteria,1MX7W@1224|Proteobacteria,2VMB9@28216|Betaproteobacteria,1K1M2@119060|Burkholderiaceae	28216|Betaproteobacteria	Q	PFAM intradiol ring-cleavage dioxygenase	-	-	1.13.11.1	ko:K03381	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	M00568	R00817,R04258,R05299,R08114,R08115,R09134	RC00388,RC00535,RC01366	ko00000,ko00001,ko00002,ko01000	-	-	-	Dioxygenase_C,Dioxygenase_N
BYD2_k127_3674049_1	479432.Sros_7930	1.208e-172	549.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4EHEH@85012|Streptosporangiales	201174|Actinobacteria	I	Thiolase, C-terminal domain	pcaF	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_3674049_6	1149133.ppKF707_1760	3.609e-79	294.0	COG4177@1|root,COG4177@2|Bacteria,1NY9G@1224|Proteobacteria,1TBH0@1236|Gammaproteobacteria,1YHIP@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	U	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_3674049_4	1123060.JONP01000011_gene3074	4.178e-93	326.0	COG0559@1|root,COG0559@2|Bacteria,1QDNH@1224|Proteobacteria,2U1CJ@28211|Alphaproteobacteria,2JTED@204441|Rhodospirillales	204441|Rhodospirillales	E	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
BYD2_k127_3674049_9	1149133.ppKF707_1758	2.862e-73	264.0	COG0410@1|root,COG0410@2|Bacteria,1MVVC@1224|Proteobacteria,1SNHZ@1236|Gammaproteobacteria,1YHG4@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_3674049_7	196367.JNFG01000201_gene2742	1.321e-78	268.0	COG0411@1|root,COG0411@2|Bacteria,1MUFT@1224|Proteobacteria,2VZHK@28216|Betaproteobacteria,1K943@119060|Burkholderiaceae	28216|Betaproteobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_3679461_1	365528.KB891208_gene2834	7.943e-59	218.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_3679461_0	1394178.AWOO02000046_gene6514	9.431e-89	307.0	COG0657@1|root,COG0657@2|Bacteria,2I6Z1@201174|Actinobacteria	201174|Actinobacteria	I	Esterase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
BYD2_k127_3679461_2	649638.Trad_0372	1.079e-09	63.0	COG1503@1|root,COG1503@2|Bacteria,1WN5J@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	J	translation release factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3687139_4	471852.Tcur_2020	1.76e-22	103.0	COG1670@1|root,COG1670@2|Bacteria,2GR79@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
BYD2_k127_3687139_1	313624.NSP_13800	1.278e-108	377.0	COG0438@1|root,COG1216@1|root,COG0438@2|Bacteria,COG1216@2|Bacteria,1G705@1117|Cyanobacteria,1HP47@1161|Nostocales	1117|Cyanobacteria	M	Glycosyltransferase like family 2	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1,Glycos_transf_2,RgpF
BYD2_k127_3687139_0	2002.JOEQ01000017_gene7846	6.464e-130	448.0	COG3903@1|root,COG3903@2|Bacteria,2GIRS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator, SARP family	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,NB-ARC,TPR_12,Trans_reg_C
BYD2_k127_3687139_2	1229780.BN381_40055	3.343e-47	183.0	COG2764@1|root,COG2764@2|Bacteria,2IKY5@201174|Actinobacteria,3UX0U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	3-demethylubiquinone-9 3-methyltransferase	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	3-dmu-9_3-mt
BYD2_k127_3687139_3	1313172.YM304_25150	7.41e-23	108.0	28TMQ@1|root,3459Q@2|Bacteria,2H8NA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3687139_5	1380356.JNIK01000004_gene134	3.616e-05	50.0	2E9QE@1|root,333WR@2|Bacteria,2I2DC@201174|Actinobacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_36980_0	1229780.BN381_50029	2.609e-63	239.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,3UXN4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
BYD2_k127_3700394_0	1229780.BN381_80377	1.531e-145	475.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
BYD2_k127_3700394_3	653045.Strvi_3217	2.11e-10	71.0	COG0842@1|root,COG0842@2|Bacteria,2GJGH@201174|Actinobacteria	201174|Actinobacteria	V	transport, permease protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_3700394_1	1120936.KB907208_gene734	5.003e-70	251.0	COG1131@1|root,COG1131@2|Bacteria,2GKI7@201174|Actinobacteria,4EHBY@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_3700394_2	1380386.JIAW01000002_gene5520	1.565e-21	98.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,236KX@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_372973_1	1229780.BN381_130116	7.68e-172	551.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,3UX5K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
BYD2_k127_372973_5	479434.Sthe_1384	5.018e-43	169.0	COG1321@1|root,COG1918@1|root,COG1321@2|Bacteria,COG1918@2|Bacteria,2G6N4@200795|Chloroflexi,27YBV@189775|Thermomicrobia	189775|Thermomicrobia	K	FeoA	-	-	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
BYD2_k127_372973_3	234621.RER_56320	3.884e-68	237.0	COG1545@1|root,COG1545@2|Bacteria,2IFQP@201174|Actinobacteria,4G0JI@85025|Nocardiaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
BYD2_k127_372973_0	935866.JAER01000023_gene2288	7.912e-200	636.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,4DPZ9@85009|Propionibacteriales	201174|Actinobacteria	I	Beta-ketoacyl synthase, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_N,ketoacyl-synt
BYD2_k127_372973_4	1123320.KB889697_gene8963	1.155e-53	209.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria	201174|Actinobacteria	I	dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
BYD2_k127_372973_2	479432.Sros_2090	3.453e-110	364.0	COG1028@1|root,COG1028@2|Bacteria,2GN3D@201174|Actinobacteria,4EFK1@85012|Streptosporangiales	201174|Actinobacteria	IQ	KR domain	-	GO:0003674,GO:0003824,GO:0004303,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006066,GO:0006629,GO:0007568,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0009719,GO:0009725,GO:0009987,GO:0010033,GO:0014070,GO:0016125,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0018812,GO:0030283,GO:0032502,GO:0033764,GO:0033993,GO:0042221,GO:0042493,GO:0042579,GO:0042802,GO:0042803,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0044594,GO:0046983,GO:0048545,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071310,GO:0071407,GO:0071704,GO:1901360,GO:1901615,GO:1902652	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
BYD2_k127_372973_6	745014.OMB55_00007370	1.785e-33	133.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,1RPZ9@1236|Gammaproteobacteria,1J7GJ@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	C	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_376844_12	1214101.BN159_5119	3.184e-32	135.0	COG0310@1|root,COG0310@2|Bacteria,2GK2U@201174|Actinobacteria	201174|Actinobacteria	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
BYD2_k127_376844_11	345341.KUTG_03432	6.264e-39	163.0	COG0007@1|root,COG0007@2|Bacteria,2GK3B@201174|Actinobacteria,4DYZE@85010|Pseudonocardiales	201174|Actinobacteria	H	Uroporphyrin-III C-methyltransferase	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,NAD_binding_7,TP_methylase
BYD2_k127_376844_8	1150864.MILUP08_43861	9.166e-48	198.0	COG2082@1|root,COG2082@2|Bacteria,2GK0B@201174|Actinobacteria,4DE9T@85008|Micromonosporales	201174|Actinobacteria	H	Precorrin-8X methylmutase	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
BYD2_k127_376844_7	251221.35213114	1.47e-50	205.0	COG1010@1|root,COG2073@1|root,COG1010@2|Bacteria,COG2073@2|Bacteria,1G10M@1117|Cyanobacteria	1117|Cyanobacteria	H	precorrin-3B C17-methyltransferase	cobJ	-	2.1.1.131,3.7.1.12	ko:K13541	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R07772	RC00003,RC01293,RC01545,RC02097,RC03471	ko00000,ko00001,ko01000	-	-	-	CbiG_C,CbiG_N,CbiG_mid,TP_methylase
BYD2_k127_376844_6	1463879.JOHP01000011_gene1179	8.435e-56	222.0	COG2241@1|root,COG2242@1|root,COG2241@2|Bacteria,COG2242@2|Bacteria,2GM8G@201174|Actinobacteria	201174|Actinobacteria	H	Precorrin-6y C5,15-methyltransferase	cobL1	-	2.1.1.132	ko:K00595	ko00860,ko01100,map00860,map01100	-	R05149	RC00003,RC01279	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,TP_methylase
BYD2_k127_376844_14	1122939.ATUD01000003_gene3296	1.73e-15	87.0	COG0007@1|root,COG0007@2|Bacteria,2H1VF@201174|Actinobacteria,4CPVP@84995|Rubrobacteria	84995|Rubrobacteria	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	-	-	-	-	-	-	-	-	-	-	-	-	TP_methylase
BYD2_k127_376844_0	345341.KUTG_03430	5.042e-94	329.0	COG2875@1|root,COG2875@2|Bacteria,2GJ97@201174|Actinobacteria,4DXAP@85010|Pseudonocardiales	201174|Actinobacteria	H	Belongs to the precorrin methyltransferase family	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
BYD2_k127_376844_9	68219.JNXI01000015_gene799	2.691e-46	179.0	COG2243@1|root,COG2243@2|Bacteria,2GUI0@201174|Actinobacteria	201174|Actinobacteria	H	Precorrin-2 C(20)-methyltransferase	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
BYD2_k127_376844_10	543632.JOJL01000039_gene1681	9.965e-46	176.0	COG0500@1|root,COG2226@2|Bacteria,2I4T7@201174|Actinobacteria,4DMSC@85008|Micromonosporales	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_20
BYD2_k127_376844_2	656024.FsymDg_4333	1.491e-73	257.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4ESC1@85013|Frankiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_376844_16	1172181.KB911698_gene5831	1.391e-07	55.0	COG3315@1|root,COG3315@2|Bacteria,2GJIS@201174|Actinobacteria	201174|Actinobacteria	Q	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_376844_1	298654.FraEuI1c_2049	9.05e-86	304.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	cyp142A3	GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0006066,GO:0006629,GO:0006706,GO:0006707,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008395,GO:0009056,GO:0016042,GO:0016125,GO:0016127,GO:0016491,GO:0016705,GO:0016709,GO:0020037,GO:0030312,GO:0031073,GO:0036199,GO:0044238,GO:0044281,GO:0044282,GO:0044464,GO:0046164,GO:0046906,GO:0048037,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1901615,GO:1901616,GO:1902652	1.14.13.221	ko:K16046	ko00984,ko01120,map00984,map01120	-	R09859,R11361	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
BYD2_k127_376844_17	550540.Fbal_0689	6.166e-07	63.0	COG1309@1|root,COG1309@2|Bacteria,1NGCB@1224|Proteobacteria	1224|Proteobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_376844_5	1282876.BAOK01000001_gene3434	3.591e-59	209.0	COG1917@1|root,COG1917@2|Bacteria,1RB86@1224|Proteobacteria	1224|Proteobacteria	S	PFAM Cupin 2 conserved barrel domain protein	-	-	1.13.11.41	ko:K05913	ko00363,ko01120,map00363,map01120	-	R01305	RC00415,RC01565	ko00000,ko00001,ko01000	-	-	-	Cupin_7
BYD2_k127_376844_4	304371.MCP_2977	3.275e-64	238.0	arCOG11014@1|root,arCOG11014@2157|Archaea	2157|Archaea	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
BYD2_k127_376844_13	290399.Arth_4114	3.818e-26	113.0	COG3809@1|root,COG3809@2|Bacteria	2|Bacteria	S	Transcription factor zinc-finger	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
BYD2_k127_376844_15	1229780.BN381_10211	1.39e-12	76.0	2CIFA@1|root,348QY@2|Bacteria,2H88E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_376844_3	58123.JOFJ01000014_gene4986	9.629e-67	233.0	COG1309@1|root,COG1309@2|Bacteria,2GJ7G@201174|Actinobacteria,4EJK5@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_376844_18	1122611.KB903941_gene2092	2.572e-06	58.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4EHYK@85012|Streptosporangiales	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_3772521_1	365528.KB891102_gene4556	1.634e-184	603.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4EU1V@85013|Frankiales	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_3772521_0	452637.Oter_2190	4.674e-186	614.0	COG1472@1|root,COG1472@2|Bacteria,46UPF@74201|Verrucomicrobia,3K900@414999|Opitutae	414999|Opitutae	G	PFAM glycoside hydrolase family 3 domain protein	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
BYD2_k127_3772521_2	1229780.BN381_170003	2.135e-181	593.0	COG1290@1|root,COG1290@2|Bacteria,2GJ1E@201174|Actinobacteria,3UWCW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Cytochrome b/b6/petB	qcrB	-	-	ko:K03891	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrom_B_N_2
BYD2_k127_3772521_3	1121877.JQKF01000003_gene1556	5.651e-67	244.0	COG0723@1|root,COG0723@2|Bacteria,2GIX6@201174|Actinobacteria,4CNF9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rieske [2Fe-2S] domain	-	-	-	ko:K03890	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Rieske
BYD2_k127_3772521_4	298653.Franean1_1810	9.05e-60	216.0	COG2010@1|root,COG2010@2|Bacteria,2GKUB@201174|Actinobacteria,4ESET@85013|Frankiales	201174|Actinobacteria	C	cytochrome C	qcrC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03889	ko00190,ko01100,map00190,map01100	M00151	-	-	ko00000,ko00001,ko00002	-	-	-	Cytochrome_CBB3
BYD2_k127_3809066_0	1298863.AUEP01000003_gene2771	2.5e-45	168.0	COG1028@1|root,COG1028@2|Bacteria,2GNVA@201174|Actinobacteria,4DTR0@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_3809066_3	106370.Francci3_1497	2.212e-20	102.0	COG2839@1|root,COG2839@2|Bacteria,2IQDE@201174|Actinobacteria,4EW98@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF456)	-	-	-	ko:K09793	-	-	-	-	ko00000	-	-	-	DUF456
BYD2_k127_3809066_2	1210884.HG799467_gene13402	5.761e-41	174.0	COG5305@1|root,COG5305@2|Bacteria,2J08D@203682|Planctomycetes	203682|Planctomycetes	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
BYD2_k127_3809066_1	1313172.YM304_20220	3.222e-45	168.0	2DMMI@1|root,32SFN@2|Bacteria	2|Bacteria	S	Protein of unknown function (DUF3151)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3151
BYD2_k127_3809066_4	1229780.BN381_50095	7.807e-12	69.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria	201174|Actinobacteria	K	Esterase of the alpha-beta hydrolase superfamily	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_3810840_0	1287276.X752_13075	4.769e-124	403.0	COG3386@1|root,COG3386@2|Bacteria,1QN8Y@1224|Proteobacteria,2U82N@28211|Alphaproteobacteria,43PGE@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	G	SMP-30 gluconolaconase LRE-like	-	-	-	-	-	-	-	-	-	-	-	-	SGL
BYD2_k127_3810840_5	1313172.YM304_32980	3.358e-32	132.0	COG1430@1|root,COG1430@2|Bacteria,2IKSE@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
BYD2_k127_3810840_2	1313172.YM304_32990	2.307e-76	269.0	COG0313@1|root,COG0313@2|Bacteria,2GJ9Q@201174|Actinobacteria,4CNAK@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Tetrapyrrole (Corrin/Porphyrin) Methylases	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
BYD2_k127_3810840_3	1246995.AFR_11890	6.387e-46	183.0	COG0346@1|root,COG0346@2|Bacteria,2I9G1@201174|Actinobacteria,4DEZW@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3810840_1	1313172.YM304_10860	2.842e-117	386.0	COG1085@1|root,COG1085@2|Bacteria,2I2DM@201174|Actinobacteria,4CMV6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Domain of unknown function (DUF4921)	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
BYD2_k127_3810840_4	1123023.JIAI01000002_gene5476	4.243e-44	168.0	COG0030@1|root,COG0030@2|Bacteria,2GIZ8@201174|Actinobacteria,4DYTH@85010|Pseudonocardiales	201174|Actinobacteria	J	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_3820413_0	66874.JOFS01000004_gene5306	1.372e-05	57.0	COG0642@1|root,COG2205@2|Bacteria,2I2WT@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_3847845_2	1229780.BN381_100154	7.268e-106	363.0	COG0515@1|root,COG0515@2|Bacteria,2GJ1J@201174|Actinobacteria,3UW9J@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KLT	Serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
BYD2_k127_3847845_5	1313172.YM304_42760	8.723e-46	173.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigW	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_3847845_0	525909.Afer_0030	6.046e-139	450.0	COG0492@1|root,COG0492@2|Bacteria,2GKD2@201174|Actinobacteria,4CMUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
BYD2_k127_3847845_7	1172185.KB911513_gene4470	8.924e-33	144.0	COG3118@1|root,COG3118@2|Bacteria,2IQ9T@201174|Actinobacteria,4G24Y@85025|Nocardiaceae	201174|Actinobacteria	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
BYD2_k127_3847845_3	298653.Franean1_7332	2.539e-84	288.0	COG1475@1|root,COG1475@2|Bacteria,2GNRN@201174|Actinobacteria,4ERK5@85013|Frankiales	201174|Actinobacteria	K	Belongs to the ParB family	parB	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005694,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044464,GO:0060187,GO:0071944	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
BYD2_k127_3847845_1	1313172.YM304_42850	8.71e-117	387.0	COG1192@1|root,COG1192@2|Bacteria,2GMU7@201174|Actinobacteria,4CMSR@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cellulose biosynthesis protein BcsQ	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
BYD2_k127_3847845_8	1229780.BN381_60003	1.454e-31	138.0	COG0357@1|root,COG0357@2|Bacteria	2|Bacteria	J	rRNA methyltransferase activity	rsmG	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
BYD2_k127_3847845_6	1313172.YM304_42870	9.287e-45	175.0	COG1847@1|root,COG1847@2|Bacteria,2GPZK@201174|Actinobacteria,4CN3J@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative single-stranded nucleic acids-binding domain	-	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,R3H
BYD2_k127_3847845_4	1229780.BN381_100163	1.018e-53	202.0	COG0706@1|root,COG0706@2|Bacteria,2GJBU@201174|Actinobacteria,3UWKK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	60Kd inner membrane protein	yidC	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
BYD2_k127_3847845_9	1229780.BN381_100164	1.757e-20	97.0	COG0759@1|root,COG0759@2|Bacteria,2GQZG@201174|Actinobacteria,3UWY8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Could be involved in insertion of integral membrane proteins into the membrane	ytjA	-	-	ko:K08998	-	-	-	-	ko00000	-	-	-	Haemolytic
BYD2_k127_3847845_13	656024.FsymDg_0004	3.882e-07	60.0	COG0594@1|root,COG0594@2|Bacteria	2|Bacteria	J	ribonuclease P activity	rnpA	GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904	3.1.26.5	ko:K03536,ko:K08998	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
BYD2_k127_3847845_12	1203190.CAJP01000011_gene754	5.33e-08	61.0	COG0230@1|root,COG0230@2|Bacteria,2GQFY@201174|Actinobacteria,22P7M@1653|Corynebacteriaceae	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL34 family	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
BYD2_k127_3847845_11	1229780.BN381_100166	2.275e-09	67.0	COG0593@1|root,COG0593@2|Bacteria,2GJKI@201174|Actinobacteria,3UW7I@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C
BYD2_k127_3854555_0	1313172.YM304_03480	1.645e-311	980.0	COG0550@1|root,COG1754@1|root,COG0550@2|Bacteria,COG1754@2|Bacteria,2GJU7@201174|Actinobacteria,4CMPI@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,Toprim_C_rpt
BYD2_k127_3854555_3	1313172.YM304_03470	8.644e-54	199.0	COG0125@1|root,COG0125@2|Bacteria,2HF93@201174|Actinobacteria,4CNDK@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis	tmk	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylate_kin
BYD2_k127_3854555_1	1313172.YM304_03460	6.928e-66	243.0	COG0470@1|root,COG0470@2|Bacteria	2|Bacteria	L	replication factor c	holB	-	2.7.7.7	ko:K02341,ko:K02343,ko:K09384	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
BYD2_k127_3864480_7	338966.Ppro_0858	2.492e-06	57.0	COG0599@1|root,COG0599@2|Bacteria	2|Bacteria	S	peroxiredoxin activity	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
BYD2_k127_3864480_5	350058.Mvan_3636	3.119e-07	59.0	COG3462@1|root,COG3462@2|Bacteria,2GRGM@201174|Actinobacteria,23B0W@1762|Mycobacteriaceae	201174|Actinobacteria	S	membrane protein (DUF2078)	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	SHOCT
BYD2_k127_3864480_1	926550.CLDAP_02880	6.176e-49	185.0	COG2128@1|root,COG2128@2|Bacteria,2G7D8@200795|Chloroflexi	200795|Chloroflexi	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_3864480_6	298653.Franean1_4795	6.23e-07	55.0	2CI2I@1|root,32S76@2|Bacteria,2GK9P@201174|Actinobacteria,4EVAY@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3864480_2	1449976.KALB_4780	9.272e-49	183.0	2E4HJ@1|root,32ZCP@2|Bacteria,2IIYC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3864480_0	383372.Rcas_1001	2.168e-54	197.0	COG0596@1|root,COG0596@2|Bacteria,2G8HQ@200795|Chloroflexi,376XF@32061|Chloroflexia	32061|Chloroflexia	S	PFAM alpha beta hydrolase fold	-	-	3.8.1.3	ko:K01561	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
BYD2_k127_3864480_3	1380393.JHVP01000004_gene612	1.079e-09	63.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3
BYD2_k127_3886480_2	251221.35214789	7.34e-51	196.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
BYD2_k127_3886480_1	103733.JNYO01000025_gene8911	1.364e-64	239.0	COG3835@1|root,COG3835@2|Bacteria,2GRBZ@201174|Actinobacteria,4E2N5@85010|Pseudonocardiales	201174|Actinobacteria	KT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
BYD2_k127_3886480_0	479435.Kfla_1387	2.523e-92	306.0	COG2318@1|root,COG2318@2|Bacteria,2HUJD@201174|Actinobacteria,4DR6E@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
BYD2_k127_3886480_4	1463917.JODC01000001_gene174	1.62e-11	69.0	COG4251@1|root,COG4251@2|Bacteria,2I2KA@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K18351	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_3886480_3	1211815.CBYP010000075_gene2952	3.758e-25	117.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
BYD2_k127_3886480_5	931627.MycrhDRAFT_1714	5.272e-05	48.0	COG0493@1|root,COG0493@2|Bacteria,2GJ4A@201174|Actinobacteria,232NA@1762|Mycobacteriaceae	201174|Actinobacteria	C	4Fe-4S binding domain	-	-	1.18.1.2,1.19.1.1	ko:K00528	-	-	R10159	-	ko00000,ko01000	-	-	-	Fer4,Pyr_redox_2
BYD2_k127_3889828_0	1313172.YM304_09040	5.001e-139	452.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	201174|Actinobacteria	D	Cell division protein FtsA	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
BYD2_k127_3889828_3	1313172.YM304_09020	1.195e-53	192.0	COG0314@1|root,COG0314@2|Bacteria,2HG21@201174|Actinobacteria,4CN80@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoaE protein	-	-	2.8.1.12	ko:K03635	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09395	RC02507	ko00000,ko00001,ko01000	-	-	-	MoaE
BYD2_k127_3889828_4	1121372.AULK01000009_gene640	1.763e-21	109.0	COG0265@1|root,COG0265@2|Bacteria,2GJJ3@201174|Actinobacteria,4FN9N@85023|Microbacteriaceae	201174|Actinobacteria	O	Domain present in PSD-95, Dlg, and ZO-1/2.	pepA	-	-	ko:K08372	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ_2,Trypsin_2
BYD2_k127_3889828_2	1313172.YM304_09000	7.017e-61	224.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria	201174|Actinobacteria	GM	Epimerase dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
BYD2_k127_3889828_1	1313172.YM304_07800	1.934e-89	310.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,4CNC4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
BYD2_k127_3890172_12	1157635.KB892032_gene6112	7.735e-45	176.0	COG0477@1|root,COG2814@2|Bacteria,2GIR8@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	ydeG	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,Sugar_tr
BYD2_k127_3890172_7	208444.JNYY01000005_gene6566	2.929e-68	242.0	COG1522@1|root,COG1522@2|Bacteria,2IFSQ@201174|Actinobacteria,4E2K1@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
BYD2_k127_3890172_18	1122138.AQUZ01000074_gene7330	7.231e-22	108.0	29PQU@1|root,30AP1@2|Bacteria,2IFHX@201174|Actinobacteria,4DSGB@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF1203)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1203
BYD2_k127_3890172_3	1242864.D187_003353	1.441e-105	357.0	COG4325@1|root,COG4325@2|Bacteria,1MXTM@1224|Proteobacteria,42NU4@68525|delta/epsilon subdivisions,2WKV0@28221|Deltaproteobacteria,2YVPN@29|Myxococcales	28221|Deltaproteobacteria	S	Predicted membrane protein (DUF2254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2254
BYD2_k127_3890172_2	1236902.ANAS01000005_gene4929	7.445e-158	522.0	COG0475@1|root,COG0475@2|Bacteria,2I7Q8@201174|Actinobacteria,4ERA4@85012|Streptosporangiales	201174|Actinobacteria	P	Zn-finger in ubiquitin-hydrolases and other protein	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N,zf-UBP
BYD2_k127_3890172_4	479432.Sros_2735	3.803e-101	351.0	COG1266@1|root,COG1266@2|Bacteria,2I2YJ@201174|Actinobacteria,4EIQQ@85012|Streptosporangiales	201174|Actinobacteria	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
BYD2_k127_3890172_10	263358.VAB18032_17890	5.399e-46	175.0	COG3371@1|root,COG3371@2|Bacteria,2IMS7@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF998)	-	-	-	-	-	-	-	-	-	-	-	-	DUF998
BYD2_k127_3890172_14	561175.KB894096_gene605	3.295e-39	153.0	COG1309@1|root,COG1309@2|Bacteria,2HAUK@201174|Actinobacteria,4EP2S@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_3890172_5	930171.Asphe3_30260	4.639e-73	256.0	COG3568@1|root,COG3568@2|Bacteria,2GNF9@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_3890172_15	296591.Bpro_2748	1.654e-36	146.0	COG0500@1|root,COG2226@2|Bacteria,1MZVH@1224|Proteobacteria,2VZ2M@28216|Betaproteobacteria	28216|Betaproteobacteria	H	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_3890172_17	479432.Sros_4332	1.043e-23	105.0	2DWQ8@1|root,341E2@2|Bacteria,2IRXG@201174|Actinobacteria,4EQWQ@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3890172_16	1077972.ARGLB_039_00800	1.014e-29	119.0	COG0346@1|root,COG0346@2|Bacteria,2HTKK@201174|Actinobacteria,1WBPU@1268|Micrococcaceae	201174|Actinobacteria	E	Glyoxalase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3890172_21	1121877.JQKF01000043_gene1156	8.98e-05	51.0	COG2361@1|root,COG2361@2|Bacteria,2GUED@201174|Actinobacteria,4CNZ4@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
BYD2_k127_3890172_20	1380386.JIAW01000001_gene4730	5.384e-05	51.0	COG2315@1|root,COG2315@2|Bacteria,2IHRR@201174|Actinobacteria	201174|Actinobacteria	K	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_3890172_8	1206744.BAGL01000063_gene4683	7.885e-62	223.0	COG3871@1|root,COG3871@2|Bacteria,2I4HQ@201174|Actinobacteria,4G9UN@85025|Nocardiaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_3890172_1	1380386.JIAW01000013_gene2594	3.323e-196	620.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,2334N@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_3890172_9	1380386.JIAW01000013_gene2593	1.714e-48	175.0	COG3795@1|root,COG3795@2|Bacteria,2IMCW@201174|Actinobacteria,23AH1@1762|Mycobacteriaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_3890172_6	1120950.KB892781_gene428	4.83e-69	244.0	COG2764@1|root,COG2764@2|Bacteria,2IG41@201174|Actinobacteria,4DVT3@85009|Propionibacteriales	201174|Actinobacteria	S	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	ko:K04750	-	-	-	-	ko00000	-	-	-	Glyoxalase
BYD2_k127_3890172_13	390989.JOEG01000022_gene2327	7.287e-42	167.0	COG3899@1|root,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4DAX8@85008|Micromonosporales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,DZR,GerE,Guanylate_cyc,Trans_reg_C
BYD2_k127_3890172_11	345341.KUTG_07442	1.937e-45	179.0	COG2267@1|root,COG2267@2|Bacteria,2HM71@201174|Actinobacteria,4EEVY@85010|Pseudonocardiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_3890172_19	391613.RTM1035_10570	2.133e-15	89.0	COG3809@1|root,COG3809@2|Bacteria,1N6ZY@1224|Proteobacteria,2UFVY@28211|Alphaproteobacteria,46R4X@74030|Roseovarius	28211|Alphaproteobacteria	S	protein conserved in bacteria	-	-	-	ko:K09981	-	-	-	-	ko00000	-	-	-	zf-TFIIB
BYD2_k127_3890172_0	251221.35214789	6.414e-270	854.0	COG0474@1|root,COG0474@2|Bacteria,1G0JX@1117|Cyanobacteria	1117|Cyanobacteria	P	ATPase, P-type (transporting), HAD superfamily, subfamily IC	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase,Hydrolase_3
BYD2_k127_3890780_19	525909.Afer_0728	2.498e-48	174.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CMRS@84992|Acidimicrobiia	84992|Acidimicrobiia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
BYD2_k127_3890780_12	935261.JAGL01000014_gene3634	3.704e-73	273.0	COG3119@1|root,COG3119@2|Bacteria	2|Bacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest,Sulfatase
BYD2_k127_3890780_22	1057002.KB905370_gene5443	4.518e-20	98.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	ko:K06219	-	-	-	-	ko00000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
BYD2_k127_3890780_23	485915.Dret_1183	1.058e-12	81.0	2ECWR@1|root,336TY@2|Bacteria,1NAQG@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
BYD2_k127_3890780_15	1121372.AULK01000002_gene853	2.079e-64	236.0	COG0438@1|root,COG0438@2|Bacteria,2GJBP@201174|Actinobacteria,4FN4A@85023|Microbacteriaceae	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1,Stealth_CR1,Stealth_CR2,Stealth_CR3,Stealth_CR4
BYD2_k127_3890780_21	1316936.K678_05428	1.956e-39	166.0	COG2327@1|root,COG2327@2|Bacteria,1RK8W@1224|Proteobacteria	1224|Proteobacteria	S	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
BYD2_k127_3890780_24	1229780.BN381_330026	5.961e-06	59.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
BYD2_k127_3890780_1	1380347.JNII01000007_gene391	1.053e-156	516.0	COG0438@1|root,COG2227@1|root,COG0438@2|Bacteria,COG2227@2|Bacteria,2IA6D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4
BYD2_k127_3890780_10	644283.Micau_2846	7.464e-74	274.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
BYD2_k127_3890780_9	426355.Mrad2831_1216	6.226e-82	292.0	COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria,1NBIU@1224|Proteobacteria,2UFYB@28211|Alphaproteobacteria	28211|Alphaproteobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
BYD2_k127_3890780_8	298655.KI912266_gene711	3.15e-86	311.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
BYD2_k127_3890780_13	263358.VAB18032_23365	1.111e-71	268.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
BYD2_k127_3890780_3	1380347.JNII01000007_gene385	1.426e-122	406.0	COG1134@1|root,COG1134@2|Bacteria,2GIVF@201174|Actinobacteria,4ESAJ@85013|Frankiales	201174|Actinobacteria	GM	PFAM ABC transporter related	rfbB2	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
BYD2_k127_3890780_14	479431.Namu_4205	2.948e-65	234.0	COG1682@1|root,COG1682@2|Bacteria,2GP5K@201174|Actinobacteria,4ESU0@85013|Frankiales	201174|Actinobacteria	GM	Transport permease protein	wzm	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_3890780_18	220664.PFL_5493	2.432e-50	198.0	COG1216@1|root,COG4372@1|root,COG1216@2|Bacteria,COG4372@2|Bacteria,1R6SJ@1224|Proteobacteria	1224|Proteobacteria	M	Pfam Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
BYD2_k127_3890780_7	326424.FRAAL1236	4.397e-90	333.0	COG0438@1|root,COG0438@2|Bacteria,2IJ4J@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase, group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_3890780_2	469383.Cwoe_3710	9.527e-132	456.0	COG1215@1|root,COG1215@2|Bacteria,2I2PK@201174|Actinobacteria,4CPE1@84995|Rubrobacteria	84995|Rubrobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_3890780_16	313625.BL107_06159	1.889e-54	218.0	COG0463@1|root,COG0463@2|Bacteria,1GMYZ@1117|Cyanobacteria,1H00Z@1129|Synechococcus	1117|Cyanobacteria	M	COG0463 Glycosyltransferases involved in cell wall biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_3890780_6	1463825.JNXC01000001_gene5547	1.182e-105	377.0	COG1215@1|root,COG2227@1|root,COG4942@1|root,COG1215@2|Bacteria,COG2227@2|Bacteria,COG4942@2|Bacteria,2I4KI@201174|Actinobacteria,4DYH9@85010|Pseudonocardiales	201174|Actinobacteria	DHM	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_11
BYD2_k127_3890780_11	211114.JOEF01000024_gene72	2.796e-73	255.0	COG0504@1|root,COG0504@2|Bacteria,2I8KR@201174|Actinobacteria,4EBR6@85010|Pseudonocardiales	201174|Actinobacteria	F	Glutamine amidotransferase class-I	-	-	-	-	-	-	-	-	-	-	-	-	GATase
BYD2_k127_3890780_5	298653.Franean1_1977	2.865e-119	404.0	COG0500@1|root,COG2226@2|Bacteria,2H0T3@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_3890780_4	1333998.M2A_1935	3.085e-121	399.0	COG1703@1|root,COG1703@2|Bacteria,1MVI0@1224|Proteobacteria,2TS96@28211|Alphaproteobacteria,4BPNJ@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	E	ArgK protein	argK	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
BYD2_k127_3890780_20	1095767.CAHD01000163_gene2999	1.518e-46	182.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	mprF	-	-	ko:K07027,ko:K20468	-	-	-	-	ko00000,ko02000	4.D.2,4.D.2.4.1	-	-	LPG_synthase_TM
BYD2_k127_3890780_17	469383.Cwoe_3711	1.226e-53	199.0	COG0500@1|root,COG2226@2|Bacteria,2HNEB@201174|Actinobacteria,4CP8F@84995|Rubrobacteria	84995|Rubrobacteria	Q	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_3890780_0	1231392.OCGS_0525	1.633e-294	912.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Methylmalonyl-CoA mutase	bhbA	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,MM_CoA_mutase
BYD2_k127_3894631_7	1306990.BARG01000018_gene1582	8.084e-19	95.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
BYD2_k127_3894631_5	1120948.KB903218_gene2005	3.983e-35	142.0	COG0789@1|root,COG0789@2|Bacteria,2IFX0@201174|Actinobacteria,4E6WK@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
BYD2_k127_3894631_0	35754.JNYJ01000020_gene153	6.446e-222	702.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria,4DCQS@85008|Micromonosporales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
BYD2_k127_3894631_1	706587.Desti_3549	1.237e-155	525.0	COG0421@1|root,COG0421@2|Bacteria,1P220@1224|Proteobacteria,42NG6@68525|delta/epsilon subdivisions,2WIRU@28221|Deltaproteobacteria,2MQH9@213462|Syntrophobacterales	28221|Deltaproteobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3894631_3	105559.Nwat_1530	4.809e-100	336.0	COG1295@1|root,COG1295@2|Bacteria,1MXQA@1224|Proteobacteria,1RP8E@1236|Gammaproteobacteria,1X06N@135613|Chromatiales	135613|Chromatiales	S	Virulence factor BrkB	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
BYD2_k127_3894631_4	1343740.M271_04915	3.527e-83	278.0	COG1247@1|root,COG1247@2|Bacteria,2IHVW@201174|Actinobacteria	201174|Actinobacteria	M	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_3894631_6	1210045.ALNP01000011_gene985	2.087e-21	97.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
BYD2_k127_3894631_2	1229780.BN381_130116	1.755e-128	418.0	COG3808@1|root,COG3808@2|Bacteria,2GN8B@201174|Actinobacteria,3UX5K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
BYD2_k127_3901786_2	1122611.KB903992_gene7321	9.902e-13	70.0	COG3327@1|root,COG3327@2|Bacteria,2HHB2@201174|Actinobacteria,4EIW4@85012|Streptosporangiales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
BYD2_k127_3901786_0	1380390.JIAT01000011_gene2697	9.84e-165	548.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CPIY@84995|Rubrobacteria	84995|Rubrobacteria	S	MMPL family	-	-	-	-	-	-	-	-	-	-	-	-	MMPL
BYD2_k127_3901786_1	356851.JOAN01000016_gene6075	1.5e-34	141.0	COG4403@1|root,COG4403@2|Bacteria,2IB4N@201174|Actinobacteria,4DFIX@85008|Micromonosporales	201174|Actinobacteria	V	Lanthionine synthetase C family protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3901786_3	1313172.YM304_25150	6.919e-06	58.0	28TMQ@1|root,3459Q@2|Bacteria,2H8NA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3909288_7	1229780.BN381_50123	4.42e-30	119.0	COG0173@1|root,COG0173@2|Bacteria,2GJHU@201174|Actinobacteria,3UW76@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
BYD2_k127_3909288_9	469383.Cwoe_1560	7.052e-29	127.0	COG2852@1|root,COG5340@1|root,COG2852@2|Bacteria,COG5340@2|Bacteria,2HPSH@201174|Actinobacteria,4CR5Y@84995|Rubrobacteria	84995|Rubrobacteria	K	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
BYD2_k127_3909288_2	1313172.YM304_26410	1.798e-175	565.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
BYD2_k127_3909288_11	1123023.JIAI01000009_gene958	4.396e-11	68.0	COG4768@1|root,COG4768@2|Bacteria,2II1J@201174|Actinobacteria,4E3ET@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF948)	-	-	-	-	-	-	-	-	-	-	-	-	DUF948
BYD2_k127_3909288_13	1169154.KB897790_gene436	8.747e-06	56.0	2EGGE@1|root,33A8E@2|Bacteria,2IKUG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_3909288_0	1229780.BN381_50129	0.0	1040.0	COG0013@1|root,COG0013@2|Bacteria,2GIUG@201174|Actinobacteria,3UW8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
BYD2_k127_3909288_8	1229780.BN381_50130	1.729e-29	123.0	COG0816@1|root,COG0816@2|Bacteria,2IQB0@201174|Actinobacteria,3UX0K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	ruvX	GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
BYD2_k127_3909288_5	1211815.CBYP010000005_gene242	1.584e-63	243.0	COG1559@1|root,COG1559@2|Bacteria,2GKGQ@201174|Actinobacteria,4ESC2@85013|Frankiales	201174|Actinobacteria	S	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation	mltG	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
BYD2_k127_3909288_4	1313172.YM304_20320	3.73e-64	233.0	COG0169@1|root,COG0169@2|Bacteria,2GPQQ@201174|Actinobacteria,4CN43@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
BYD2_k127_3909288_12	326427.Cagg_2678	8.468e-09	68.0	COG2199@1|root,COG3706@2|Bacteria,2GBJP@200795|Chloroflexi,37810@32061|Chloroflexia	32061|Chloroflexia	T	Domain of unknown function (DUF4388)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4388
BYD2_k127_3909288_10	500153.JOEK01000013_gene1666	3.473e-16	89.0	COG1989@1|root,COG1989@2|Bacteria,2GJ7K@201174|Actinobacteria	201174|Actinobacteria	NOU	Peptidase A24A, prepilin type IV	pilD	-	3.4.23.43	ko:K02654	-	M00331	-	-	ko00000,ko00002,ko01000,ko01002,ko02035,ko02044	3.A.15.2	-	-	Peptidase_A24
BYD2_k127_3909288_1	1313172.YM304_20340	9.846e-183	582.0	COG0082@1|root,COG0082@2|Bacteria,2GJJN@201174|Actinobacteria,4CMPX@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
BYD2_k127_3909288_3	1313172.YM304_20360	4.506e-116	394.0	COG0337@1|root,COG0337@2|Bacteria,2GIUZ@201174|Actinobacteria,4CMXJ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	3-dehydroquinate synthase	aroB	-	-	ko:K16020	ko01051,ko01130,map01051,map01130	-	R06592	RC00847	ko00000,ko00001	-	-	-	DHQ_synthase
BYD2_k127_3909288_6	1229780.BN381_50135	4.44e-36	157.0	COG0757@1|root,COG0757@2|Bacteria,2IMBY@201174|Actinobacteria,3UWWA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes a trans-dehydration via an enolate intermediate	aroQ	-	4.2.1.10	ko:K03786,ko:K16021	ko00400,ko01051,ko01100,ko01110,ko01130,ko01230,map00400,map01051,map01100,map01110,map01130,map01230	M00022	R03084,R06593	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_II
BYD2_k127_3941202_1	1218084.BBJK01000003_gene353	3.206e-88	301.0	COG1454@1|root,COG1454@2|Bacteria,1MVPH@1224|Proteobacteria,2VM53@28216|Betaproteobacteria,1K0IU@119060|Burkholderiaceae	28216|Betaproteobacteria	C	maleylacetate reductase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
BYD2_k127_3941202_0	1301098.PKB_3302	4.491e-120	414.0	COG0683@1|root,COG0683@2|Bacteria,1N0MT@1224|Proteobacteria	1224|Proteobacteria	E	ABC transporter substrate-binding protein	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6,TAT_signal
BYD2_k127_394469_11	1313172.YM304_21020	1.769e-48	194.0	COG0658@1|root,COG0658@2|Bacteria,2GJGR@201174|Actinobacteria	201174|Actinobacteria	L	ComEC Rec2-related protein	comEC	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
BYD2_k127_394469_12	521393.JH806633_gene1470	2.871e-39	164.0	COG1555@1|root,COG1555@2|Bacteria,2IQDC@201174|Actinobacteria,4D3V2@85005|Actinomycetales	201174|Actinobacteria	L	ComEA protein	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
BYD2_k127_394469_18	1166018.FAES_5093	0.0001721	52.0	2C8RN@1|root,32RMQ@2|Bacteria,4NSD0@976|Bacteroidetes,47RVK@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_394469_7	1313172.YM304_20990	3.917e-78	271.0	COG3118@1|root,COG3118@2|Bacteria,2GJ7B@201174|Actinobacteria,4CMY0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Tetratricopeptide repeat	-	-	-	ko:K05838	-	-	-	-	ko00000,ko03110	-	-	-	TPR_20,Thioredoxin
BYD2_k127_394469_5	1229780.BN381_10252	7.836e-120	396.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,3UX9P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_394469_8	1229780.BN381_10251	4.399e-76	269.0	COG2047@1|root,COG2047@2|Bacteria,2GK8I@201174|Actinobacteria	201174|Actinobacteria	S	PAC2 family	-	-	-	-	-	-	-	-	-	-	-	-	PAC2
BYD2_k127_394469_3	1313172.YM304_20970	5.03e-136	444.0	COG2141@1|root,COG2141@2|Bacteria,2GNE9@201174|Actinobacteria	201174|Actinobacteria	C	F420-dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_394469_2	1229780.BN381_10241	2.716e-203	648.0	COG0318@1|root,COG0318@2|Bacteria	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	pks16	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008922,GO:0009058,GO:0009987,GO:0015645,GO:0016020,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016874,GO:0016877,GO:0016878,GO:0017076,GO:0019752,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044403,GO:0044419,GO:0044464,GO:0046394,GO:0051704,GO:0070566,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576	6.2.1.20	ko:K00666,ko:K01909	ko00071,map00071	-	R01406	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C,AMP-binding_C_2
BYD2_k127_394469_0	1380356.JNIK01000021_gene4515	0.0	1382.0	COG0495@1|root,COG0495@2|Bacteria,2GJI1@201174|Actinobacteria,4ERFA@85013|Frankiales	201174|Actinobacteria	J	Belongs to the class-I aminoacyl-tRNA synthetase family	leuS	GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
BYD2_k127_394469_16	1137268.AZXF01000011_gene3732	1.622e-08	66.0	COG4114@1|root,COG4114@2|Bacteria,2I21U@201174|Actinobacteria,4EQB2@85012|Streptosporangiales	201174|Actinobacteria	S	FhuF 2Fe-2S C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FhuF_C
BYD2_k127_394469_13	1313172.YM304_26740	3.992e-29	120.0	COG0799@1|root,COG0799@2|Bacteria,2IKZ3@201174|Actinobacteria,4CN96@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
BYD2_k127_394469_17	644966.Tmar_2199	4.131e-06	60.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,24AAY@186801|Clostridia,3WD9K@538999|Clostridiales incertae sedis	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	lytR	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
BYD2_k127_394469_9	1313172.YM304_26760	2.023e-65	239.0	COG1057@1|root,COG1057@2|Bacteria,2GMFZ@201174|Actinobacteria,4CN49@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
BYD2_k127_394469_4	869210.Marky_0319	2.959e-125	417.0	COG1488@1|root,COG1488@2|Bacteria,1WIWH@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	-	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase
BYD2_k127_394469_10	1229780.BN381_60027	2.227e-59	216.0	COG1335@1|root,COG1335@2|Bacteria,2IFQW@201174|Actinobacteria,3UWWF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Isochorismatase family	pncA	GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006769,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0071704,GO:0072524,GO:1901360,GO:1901564	3.5.1.19	ko:K08281	ko00760,ko01100,map00760,map01100	-	R01268	RC00100	ko00000,ko00001,ko01000	-	-	-	Isochorismatase
BYD2_k127_394469_6	1313172.YM304_26770	1.45e-109	366.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,4CMST@84992|Acidimicrobiia	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Helicase_C,ResIII,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_394469_1	1313172.YM304_26780	1.43e-217	689.0	COG3200@1|root,COG3200@2|Bacteria,2GJBX@201174|Actinobacteria,4CMTE@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Class-II DAHP synthetase family	-	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_2
BYD2_k127_394469_15	1110697.NCAST_21_00780	3.578e-10	69.0	COG0425@1|root,COG0425@2|Bacteria,2GSNH@201174|Actinobacteria	201174|Actinobacteria	O	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_394469_14	557599.MKAN_03795	4.493e-23	102.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria,237JF@1762|Mycobacteriaceae	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
BYD2_k127_3945769_4	1089552.KI911559_gene890	1.124e-78	266.0	COG1884@1|root,COG2185@1|root,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2TQYC@28211|Alphaproteobacteria,2JP9C@204441|Rhodospirillales	204441|Rhodospirillales	I	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	-	5.4.99.2	ko:K01847	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00376,M00741	R00833	RC00395	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
BYD2_k127_3945769_2	1229780.BN381_110033	5.01e-103	344.0	COG1215@1|root,COG1215@2|Bacteria,2GP1D@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_3945769_5	525368.HMPREF0591_2394	5.453e-61	224.0	COG1117@1|root,COG1117@2|Bacteria,2ID49@201174|Actinobacteria,2384V@1762|Mycobacteriaceae	201174|Actinobacteria	P	Belongs to the ABC transporter superfamily	pstB	-	-	ko:K02068	-	M00211	-	-	ko00000,ko00002,ko02000	-	-	-	ABC_tran
BYD2_k127_3945769_3	216594.MMAR_4973	3.642e-80	276.0	COG0390@1|root,COG0390@2|Bacteria,2GMHX@201174|Actinobacteria,235M0@1762|Mycobacteriaceae	201174|Actinobacteria	S	Permease component	ybbM	-	-	ko:K02069	-	M00211	-	-	ko00000,ko00002,ko02000	9.B.25.1	-	-	UPF0014
BYD2_k127_3945769_1	1313172.YM304_28810	1.675e-197	625.0	COG1249@1|root,COG1249@2|Bacteria,2GIXY@201174|Actinobacteria,4CMT7@84992|Acidimicrobiia	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
BYD2_k127_3945769_0	1229780.BN381_10171	4.842e-262	818.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria,3UWDD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Biotin carboxylase C-terminal domain	-	-	6.3.4.14,6.4.1.2,6.4.1.3	ko:K11263	ko00061,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00741	R00742,R01859,R04385	RC00040,RC00097,RC00253,RC00367,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
BYD2_k127_3948478_0	1229780.BN381_100024	6.839e-99	342.0	COG0276@1|root,COG0276@2|Bacteria,2GJTQ@201174|Actinobacteria,3UWVK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the ferrous insertion into protoporphyrin IX	hemH	-	4.99.1.1,4.99.1.9	ko:K01772	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R00310,R11329	RC01012	ko00000,ko00001,ko00002,ko01000	-	-	-	Ferrochelatase
BYD2_k127_3948478_1	1157637.KB892135_gene3561	4.378e-94	314.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
BYD2_k127_3957652_2	649831.L083_7466	1.812e-46	177.0	COG1877@1|root,COG1877@2|Bacteria,2GMKW@201174|Actinobacteria,4D8RZ@85008|Micromonosporales	201174|Actinobacteria	G	Removes the phosphate from trehalose 6-phosphate to produce free trehalose	otsB	-	3.1.3.12	ko:K01087	ko00500,ko01100,map00500,map01100	-	R02778	RC00017	ko00000,ko00001,ko01000	-	-	-	Trehalose_PPase
BYD2_k127_3957652_0	1896.JOAU01000038_gene2252	2.314e-128	424.0	COG0380@1|root,COG0380@2|Bacteria,2GMX7@201174|Actinobacteria	201174|Actinobacteria	G	synthase	otsA	-	2.4.1.15,2.4.1.347	ko:K00697	ko00500,ko01100,map00500,map01100	-	R02737	RC00005,RC00049,RC02748	ko00000,ko00001,ko01000,ko01003	-	GT20	-	Glyco_transf_20
BYD2_k127_3957652_1	1229780.BN381_150091	7.224e-94	324.0	COG1929@1|root,COG1929@2|Bacteria,2GKHX@201174|Actinobacteria,3UWQJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Glycerate kinase family	garK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
BYD2_k127_3957652_3	1229780.BN381_150094	8.696e-29	131.0	COG1977@1|root,COG1977@2|Bacteria,2IQBT@201174|Actinobacteria,3UXHU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
BYD2_k127_3957652_4	525909.Afer_1846	2.051e-27	111.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CNG0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
BYD2_k127_3986332_2	215803.DB30_8770	4.162e-59	218.0	COG0406@1|root,COG0406@2|Bacteria,1RCJE@1224|Proteobacteria,42W6J@68525|delta/epsilon subdivisions,2WSAJ@28221|Deltaproteobacteria,2YZEF@29|Myxococcales	28221|Deltaproteobacteria	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
BYD2_k127_3986332_3	1120950.KB892757_gene6499	8.142e-28	118.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4DS34@85009|Propionibacteriales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
BYD2_k127_3986332_1	1380390.JIAT01000009_gene1027	1.127e-71	262.0	COG2207@1|root,COG2207@2|Bacteria,2H1NG@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_3986332_0	296591.Bpro_1404	6.955e-98	334.0	COG3268@1|root,COG3268@2|Bacteria,1MVI3@1224|Proteobacteria,2VQB7@28216|Betaproteobacteria,4AFVE@80864|Comamonadaceae	28216|Betaproteobacteria	S	Saccharopine dehydrogenase NADP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10,Sacchrp_dh_NADP
BYD2_k127_399582_11	222534.KB893783_gene5263	3.444e-28	127.0	2DRRW@1|root,33CSQ@2|Bacteria,2HU49@201174|Actinobacteria,4EWXU@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_399582_0	1957.JODX01000023_gene4173	8.648e-146	481.0	COG3214@1|root,COG3214@2|Bacteria	2|Bacteria	J	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
BYD2_k127_399582_12	1380394.JADL01000005_gene5669	1.443e-27	115.0	COG0654@1|root,COG0654@2|Bacteria,1MUN4@1224|Proteobacteria,2TQT8@28211|Alphaproteobacteria,2JWSX@204441|Rhodospirillales	204441|Rhodospirillales	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
BYD2_k127_399582_10	1121019.AUMN01000021_gene1282	4.06e-30	132.0	COG3832@1|root,COG3832@2|Bacteria,2GSCI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_399582_15	1206101.AZXC01000013_gene930	1.963e-17	93.0	COG0640@1|root,COG0640@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_399582_16	1112204.GPOL_c00890	9.873e-16	82.0	COG2365@1|root,COG3832@1|root,COG2365@2|Bacteria,COG3832@2|Bacteria,2I9IA@201174|Actinobacteria,4GFE9@85026|Gordoniaceae	201174|Actinobacteria	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2,Y_phosphatase3
BYD2_k127_399582_5	981384.AEYW01000007_gene1239	5.728e-52	192.0	COG3832@1|root,COG3832@2|Bacteria,1RJKI@1224|Proteobacteria,2UAQG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_399582_8	1313172.YM304_31580	3.265e-42	158.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria	201174|Actinobacteria	K	arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_399582_6	1349820.M707_11875	5.4e-45	166.0	COG3070@1|root,COG3070@2|Bacteria,2IRAD@201174|Actinobacteria	201174|Actinobacteria	K	TfoX N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	TfoX_N
BYD2_k127_399582_3	1120999.JONM01000001_gene1458	1.513e-91	315.0	COG2818@1|root,COG2818@2|Bacteria,1R9X5@1224|Proteobacteria,2VQC5@28216|Betaproteobacteria,2KQUT@206351|Neisseriales	206351|Neisseriales	L	DNA-3-methyladenine glycosylase I	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
BYD2_k127_399582_9	1211115.ALIQ01000244_gene3755	8.238e-34	132.0	COG2350@1|root,COG2350@2|Bacteria,1PZSP@1224|Proteobacteria,2VD3E@28211|Alphaproteobacteria,3NCTT@45404|Beijerinckiaceae	28211|Alphaproteobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_399582_4	331869.BAL199_05374	6.491e-77	262.0	COG1309@1|root,COG1309@2|Bacteria,1RBS8@1224|Proteobacteria,2U3P5@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_399582_1	298655.KI912266_gene6037	4.112e-104	343.0	COG1028@1|root,COG1028@2|Bacteria,2IJHX@201174|Actinobacteria	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_399582_7	419947.MRA_2574	1.15e-44	166.0	COG1487@1|root,COG1487@2|Bacteria,2IRPF@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	-	-	-	-	-	-	-	-	-	PIN
BYD2_k127_399582_2	365528.KB891181_gene4700	5.143e-100	334.0	COG1309@1|root,COG1309@2|Bacteria,2GTK8@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_399695_2	1313172.YM304_12950	4.652e-144	466.0	COG0661@1|root,COG0661@2|Bacteria,2GJQ6@201174|Actinobacteria,4CMRN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
BYD2_k127_399695_15	497964.CfE428DRAFT_0761	6.403e-34	150.0	28ID8@1|root,2Z8FH@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_399695_7	446470.Snas_0915	5.245e-66	244.0	COG0351@1|root,COG0351@2|Bacteria,2GKZM@201174|Actinobacteria,4EXYB@85014|Glycomycetales	201174|Actinobacteria	H	Phosphomethylpyrimidine kinase	thiD	GO:0008150,GO:0040007	2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03471,R04509	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
BYD2_k127_399695_14	1136417.AZWE01000012_gene2483	2.316e-34	141.0	COG0352@1|root,COG0352@2|Bacteria,2IIB5@201174|Actinobacteria,4DDI0@85008|Micromonosporales	201174|Actinobacteria	H	Thiamine monophosphate synthase	thiE2	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
BYD2_k127_399695_3	58123.JOFJ01000001_gene3135	1.813e-117	389.0	COG2022@1|root,COG2022@2|Bacteria,2GM62@201174|Actinobacteria,4EGR2@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
BYD2_k127_399695_21	263358.VAB18032_00955	4.425e-10	72.0	COG2104@1|root,COG2104@2|Bacteria,2I1GU@201174|Actinobacteria,4DGH6@85008|Micromonosporales	201174|Actinobacteria	H	ThiS family	thiS	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
BYD2_k127_399695_4	1003195.SCAT_1229	5.967e-112	390.0	COG0665@1|root,COG0665@2|Bacteria,2GJVR@201174|Actinobacteria	201174|Actinobacteria	E	Glycine oxidase	thiO	-	1.4.3.19	ko:K03153	ko00730,ko01100,map00730,map01100	-	R07463	RC01788	ko00000,ko00001,ko01000	-	-	-	DAO
BYD2_k127_399695_8	1146883.BLASA_0101	5.12e-54	203.0	COG0352@1|root,COG0352@2|Bacteria,2GKCN@201174|Actinobacteria,4ESI0@85013|Frankiales	201174|Actinobacteria	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
BYD2_k127_399695_0	1120972.AUMH01000002_gene2744	1.571e-281	874.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,4HC0P@91061|Bacilli	91061|Bacilli	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	iYO844.BSU08790	ThiC-associated,ThiC_Rad_SAM
BYD2_k127_399695_6	1056816.JAFQ01000004_gene317	8.78e-72	253.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
BYD2_k127_399695_20	1120948.KB903240_gene4151	4.019e-12	76.0	COG3568@1|root,COG3568@2|Bacteria,2HEP6@201174|Actinobacteria,4E819@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_399695_1	479435.Kfla_2482	3.995e-153	494.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4DNJE@85009|Propionibacteriales	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	-
BYD2_k127_399695_5	1313172.YM304_06600	5.949e-85	288.0	COG1335@1|root,COG1335@2|Bacteria,2I77A@201174|Actinobacteria,4CNYC@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
BYD2_k127_399695_16	1042377.AFPJ01000032_gene2781	9.142e-19	90.0	COG2350@1|root,COG2350@2|Bacteria,1NCHB@1224|Proteobacteria,1SG2M@1236|Gammaproteobacteria,46BI7@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_399695_10	463191.SSEG_08218	1.877e-53	191.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_399695_12	1032480.MLP_28890	2.923e-39	153.0	COG2318@1|root,COG2318@2|Bacteria	2|Bacteria	S	DinB family	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB
BYD2_k127_399695_11	110319.CF8_1402	3.817e-47	179.0	COG0748@1|root,COG0748@2|Bacteria,2IFYD@201174|Actinobacteria	201174|Actinobacteria	P	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
BYD2_k127_399695_17	221288.JH992901_gene3767	1.775e-16	93.0	COG0823@1|root,COG0823@2|Bacteria,1G8I3@1117|Cyanobacteria	1117|Cyanobacteria	U	WD40-like Beta Propeller Repeat	-	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
BYD2_k127_399695_19	1280666.ATVS01000004_gene2548	5.6e-14	82.0	COG5566@1|root,COG5566@2|Bacteria,1VEZS@1239|Firmicutes,24QVB@186801|Clostridia,4C287@830|Butyrivibrio	186801|Clostridia	S	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mor
BYD2_k127_399695_9	103733.JNYO01000064_gene6452	9.009e-54	196.0	COG0406@1|root,COG0406@2|Bacteria,2IAPP@201174|Actinobacteria,4ECXV@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoglycerate mutase family	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
BYD2_k127_399695_13	1032480.MLP_43430	7.46e-37	141.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4DP3H@85009|Propionibacteriales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_3999791_2	1206729.BAFZ01000001_gene15	1.44e-83	295.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4FUZE@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_3999791_1	1206735.BAGG01000265_gene6935	1.284e-160	532.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4FX1Q@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_3999791_3	298653.Franean1_4304	2.088e-68	244.0	COG1960@1|root,COG1960@2|Bacteria,2HQGI@201174|Actinobacteria,4EW4X@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1
BYD2_k127_3999791_0	1380356.JNIK01000015_gene2456	3.225e-166	539.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4EU84@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_3999791_4	1114959.SZMC14600_08163	4.662e-13	70.0	COG1250@1|root,COG1250@2|Bacteria,2GJBM@201174|Actinobacteria,4DYZJ@85010|Pseudonocardiales	201174|Actinobacteria	I	Dehydrogenase	fadB2	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
BYD2_k127_4026993_6	1229780.BN381_80408	7.121e-81	271.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,3UW6D@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Ribosomal protein S1-like RNA-binding domain	rpsA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
BYD2_k127_4026993_10	1229780.BN381_430004	3.666e-56	211.0	COG0237@1|root,COG0237@2|Bacteria,2GN96@201174|Actinobacteria,3UWS8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE,GrpB
BYD2_k127_4026993_14	42256.RradSPS_1549	0.0002461	53.0	29DTG@1|root,300RC@2|Bacteria,2HCYB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4026993_5	28444.JODQ01000002_gene4220	1.737e-88	298.0	COG0745@1|root,COG0745@2|Bacteria,2GMVN@201174|Actinobacteria,4EICG@85012|Streptosporangiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_4026993_4	103733.JNYO01000031_gene1523	1.333e-88	307.0	COG0642@1|root,COG0745@1|root,COG0642@2|Bacteria,COG0745@2|Bacteria,2GMHQ@201174|Actinobacteria,4DX7U@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_4026993_8	469383.Cwoe_3906	1.832e-73	256.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lpsA1	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2,PGAP1
BYD2_k127_4026993_11	1283299.AUKG01000002_gene3694	5.243e-48	184.0	COG1280@1|root,COG1280@2|Bacteria,2HPNY@201174|Actinobacteria,4CR1H@84995|Rubrobacteria	84995|Rubrobacteria	E	LysE type translocator	-	-	-	-	-	-	-	-	-	-	-	-	LysE
BYD2_k127_4026993_2	1229780.BN381_420007	4.4e-323	1001.0	COG0556@1|root,COG0556@2|Bacteria,2GJ03@201174|Actinobacteria,3UWC3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
BYD2_k127_4026993_12	211114.JOEF01000059_gene2714	4.507e-41	177.0	COG0500@1|root,COG2226@2|Bacteria,2IECW@201174|Actinobacteria,4E7BJ@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_4026993_0	284031.JNXD01000033_gene4209	0.0	1341.0	COG0178@1|root,COG0178@2|Bacteria,2GJUV@201174|Actinobacteria	201174|Actinobacteria	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	GO:0000018,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031324,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0071944,GO:0080090	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
BYD2_k127_4026993_9	1244869.H261_02756	1.987e-57	203.0	COG3542@1|root,COG3542@2|Bacteria,1RHBE@1224|Proteobacteria,2U962@28211|Alphaproteobacteria,2JSSJ@204441|Rhodospirillales	204441|Rhodospirillales	S	Cupin superfamily (DUF985)	-	-	-	ko:K09705	-	-	-	-	ko00000	-	-	-	Cupin_5
BYD2_k127_4026993_1	471852.Tcur_2817	0.0	1175.0	COG1554@1|root,COG1554@2|Bacteria,2GKEV@201174|Actinobacteria,4ENEP@85012|Streptosporangiales	201174|Actinobacteria	G	Glycosyl hydrolase family 65, C-terminal domain	-	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
BYD2_k127_4026993_3	1229780.BN381_410040	9.37e-175	559.0	COG0379@1|root,COG0379@2|Bacteria,2GM59@201174|Actinobacteria,3UWB7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	-	NadA
BYD2_k127_4026993_13	1449049.JONW01000011_gene2248	8.784e-38	147.0	COG2329@1|root,COG2329@2|Bacteria,1RHK9@1224|Proteobacteria,2TZMK@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4026993_15	105422.BBPM01000003_gene5640	0.000455	49.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria,2NIMZ@228398|Streptacidiphilus	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
BYD2_k127_4026993_7	1313172.YM304_21620	8.327e-74	251.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CMVA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
BYD2_k127_405370_28	1229780.BN381_50178	6.094e-79	289.0	COG0159@1|root,COG0159@2|Bacteria,2GN6T@201174|Actinobacteria,3UWK3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
BYD2_k127_405370_4	1229780.BN381_50177	7.877e-187	598.0	COG0133@1|root,COG0133@2|Bacteria,2GM7Z@201174|Actinobacteria,3UWAH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
BYD2_k127_405370_29	1313172.YM304_24300	6.687e-75	258.0	COG0135@1|root,COG0135@2|Bacteria,2IHPP@201174|Actinobacteria,4CN2A@84992|Acidimicrobiia	84992|Acidimicrobiia	E	N-(5'phosphoribosyl)anthranilate (PRA) isomerase	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
BYD2_k127_405370_22	1313172.YM304_24270	1.012e-85	296.0	COG0134@1|root,COG0134@2|Bacteria,2GIVV@201174|Actinobacteria,4CN2P@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Indole-3-glycerol phosphate synthase	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
BYD2_k127_405370_56	1313172.YM304_34510	7.823e-07	60.0	COG1359@1|root,COG1359@2|Bacteria	2|Bacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
BYD2_k127_405370_54	585423.KR49_07405	1.133e-14	83.0	COG0484@1|root,COG0484@2|Bacteria,1G2FB@1117|Cyanobacteria,1GZUP@1129|Synechococcus	1117|Cyanobacteria	O	Molecular chaperone	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ
BYD2_k127_405370_45	1229780.BN381_80382	1.495e-42	170.0	COG0354@1|root,COG0354@2|Bacteria,2GKP0@201174|Actinobacteria,3UX0E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Belongs to the GcvT family	ygfZ	-	-	ko:K06980	-	-	-	-	ko00000,ko03016	-	-	-	GCV_T,GCV_T_C
BYD2_k127_405370_6	1229780.BN381_80377	9.539e-152	496.0	COG1894@1|root,COG1894@2|Bacteria,2GNN9@201174|Actinobacteria,3UXSE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoF_1	-	-	-	-	-	-	-	-	-	-	-	Complex1_51K,NADH_4Fe-4S
BYD2_k127_405370_3	1229780.BN381_80375	4.874e-201	647.0	COG0147@1|root,COG0147@2|Bacteria,2GKJT@201174|Actinobacteria,3UW9N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EH	Anthranilate synthase component 1	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
BYD2_k127_405370_44	1313172.YM304_22700	5.959e-43	166.0	COG0139@1|root,COG0139@2|Bacteria,2IKKU@201174|Actinobacteria,4CN95@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP	hisI	-	3.5.4.19	ko:K01496	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04037	RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-CH
BYD2_k127_405370_48	479435.Kfla_1859	8.299e-38	153.0	COG0234@1|root,COG0234@2|Bacteria,2IHRC@201174|Actinobacteria,4DR8F@85009|Propionibacteriales	201174|Actinobacteria	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groES2	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
BYD2_k127_405370_46	1313172.YM304_22680	1.036e-41	162.0	COG2945@1|root,COG2945@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K07018	-	-	-	-	ko00000	-	-	-	Hydrolase_4
BYD2_k127_405370_17	887898.HMPREF0551_2534	2.472e-108	355.0	COG0107@1|root,COG0107@2|Bacteria,1MUS0@1224|Proteobacteria,2VHY0@28216|Betaproteobacteria,1K0MT@119060|Burkholderiaceae	28216|Betaproteobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
BYD2_k127_405370_32	1231392.OCGS_0110	2.505e-67	245.0	COG0106@1|root,COG0106@2|Bacteria,1MW6S@1224|Proteobacteria,2TRSG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
BYD2_k127_405370_35	1229780.BN381_80369	6.118e-64	225.0	COG0118@1|root,COG0118@2|Bacteria,2GIYS@201174|Actinobacteria,3UWJ0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
BYD2_k127_405370_18	1122182.KB903838_gene4197	8.871e-107	357.0	COG0330@1|root,COG0330@2|Bacteria,2GKFP@201174|Actinobacteria,4DD9W@85008|Micromonosporales	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
BYD2_k127_405370_13	1123319.AUBE01000031_gene5074	4.713e-117	396.0	COG1030@1|root,COG1030@2|Bacteria	2|Bacteria	-	-	nfeD	-	-	ko:K07403	-	-	-	-	ko00000	-	-	-	CLP_protease,NfeD
BYD2_k127_405370_25	1229780.BN381_80368	2.988e-84	301.0	COG0131@1|root,COG0131@2|Bacteria,2GKMD@201174|Actinobacteria,3UWJP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Imidazoleglycerol-phosphate dehydratase	hisB	GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	3.1.3.15,4.2.1.19	ko:K01089,ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013,R03457	RC00017,RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
BYD2_k127_405370_8	1313172.YM304_22610	7.415e-135	460.0	COG0079@1|root,COG0079@2|Bacteria,2GJ9W@201174|Actinobacteria,4CMYU@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	-	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
BYD2_k127_405370_14	1229780.BN381_80362	1.386e-114	390.0	COG0141@1|root,COG0141@2|Bacteria,2GKKA@201174|Actinobacteria,3UWFF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23	ko:K00013	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh
BYD2_k127_405370_33	1120950.KB892762_gene5486	4.728e-67	236.0	COG0177@1|root,COG0177@2|Bacteria,2GJ01@201174|Actinobacteria,4DNJN@85009|Propionibacteriales	201174|Actinobacteria	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0030312,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
BYD2_k127_405370_19	479435.Kfla_5999	1.247e-104	356.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DQRB@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
BYD2_k127_405370_27	1313172.YM304_22590	1.817e-81	281.0	COG0454@1|root,COG0456@2|Bacteria,2GM35@201174|Actinobacteria,4CN0X@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol	mshD	-	2.3.1.189	ko:K15520	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1
BYD2_k127_405370_36	1229780.BN381_450029	6.578e-64	227.0	COG1814@1|root,COG1814@2|Bacteria,2GIZ3@201174|Actinobacteria,3UWS5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	VIT family	-	-	-	-	-	-	-	-	-	-	-	-	VIT1
BYD2_k127_405370_7	1313172.YM304_22570	8.083e-146	475.0	COG0820@1|root,COG0820@2|Bacteria,2GJ48@201174|Actinobacteria,4CMPY@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Radical_SAM
BYD2_k127_405370_40	1306174.JODP01000006_gene3644	3.78e-54	200.0	COG1208@1|root,COG1208@2|Bacteria,2IEN7@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleotidyl transferase	-	-	2.7.7.13,2.7.7.99	ko:K00966,ko:K00992	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885,R11025	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transf_3,NTP_transferase
BYD2_k127_405370_37	1229780.BN381_430043	4.922e-62	222.0	COG2030@1|root,COG2030@2|Bacteria,2IHRG@201174|Actinobacteria,3UXCM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
BYD2_k127_405370_53	756272.Plabr_0405	1.331e-23	118.0	COG1994@1|root,COG1994@2|Bacteria,2J0CK@203682|Planctomycetes	203682|Planctomycetes	S	PFAM peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
BYD2_k127_405370_26	1313172.YM304_24030	1.568e-81	299.0	COG0500@1|root,COG2226@2|Bacteria,2GKFZ@201174|Actinobacteria,4CN6D@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2)	menG	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Ubie_methyltran
BYD2_k127_405370_21	1313172.YM304_24020	7.261e-86	310.0	COG1169@1|root,COG1169@2|Bacteria,2GKE8@201174|Actinobacteria,4CNAM@84992|Acidimicrobiia	84992|Acidimicrobiia	HQ	chorismate binding enzyme	-	-	5.4.4.2	ko:K02552	ko00130,ko01053,ko01100,ko01110,ko01130,map00130,map01053,map01100,map01110,map01130	M00116	R01717	RC00588	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_bind
BYD2_k127_405370_9	1343740.M271_03650	1.435e-125	436.0	COG1165@1|root,COG1165@2|Bacteria,2GMEB@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)	menD	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.2.1.9	ko:K02551	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08165	RC02186	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
BYD2_k127_405370_31	1192034.CAP_1582	4.871e-68	241.0	COG2267@1|root,COG2267@2|Bacteria,1QUFU@1224|Proteobacteria,43BQ1@68525|delta/epsilon subdivisions,2X718@28221|Deltaproteobacteria,2Z3MK@29|Myxococcales	28221|Deltaproteobacteria	I	alpha/beta hydrolase fold	menH	-	4.2.99.20	ko:K08680	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R08166	RC02148,RC02475	ko00000,ko00001,ko00002,ko01000	-	-	-	Abhydrolase_6
BYD2_k127_405370_11	644283.Micau_3633	6.882e-124	412.0	COG0520@1|root,COG0520@2|Bacteria,2GNM2@201174|Actinobacteria,4DM44@85008|Micromonosporales	201174|Actinobacteria	M	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
BYD2_k127_405370_20	1229780.BN381_430060	5.71e-86	298.0	COG1575@1|root,COG1575@2|Bacteria,2GJBS@201174|Actinobacteria,3UWJA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Belongs to the MenA family. Type 1 subfamily	menA	GO:0003674,GO:0003824,GO:0004659,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663	2.5.1.74	ko:K02548	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R05617,R06858,R10757	RC02935,RC02936,RC03264	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	UbiA
BYD2_k127_405370_30	247639.MGP2080_13859	2.23e-71	250.0	COG3217@1|root,COG3217@2|Bacteria,1Q80Q@1224|Proteobacteria,1SFUE@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Fe-S protein	-	-	-	ko:K07140	-	-	-	-	ko00000	-	-	-	MOSC,MOSC_N
BYD2_k127_405370_12	1313172.YM304_23970	2.123e-118	390.0	COG0318@1|root,COG0318@2|Bacteria,2GN9C@201174|Actinobacteria,4CN14@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.26	ko:K01911	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04030	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_405370_24	298655.KI912266_gene419	2.539e-84	288.0	COG1028@1|root,COG1028@2|Bacteria,2GMG3@201174|Actinobacteria,4ERGA@85013|Frankiales	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_405370_5	478801.Ksed_21970	3.01e-159	513.0	COG3211@1|root,COG3211@2|Bacteria,2GJKE@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial protein of unknown function (DUF839)	-	-	-	ko:K07093	-	-	-	-	ko00000	-	-	-	DUF839
BYD2_k127_405370_49	1313172.YM304_05660	7.378e-36	141.0	COG2050@1|root,COG2050@2|Bacteria,2IJB2@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_405370_2	1313172.YM304_19650	1.56e-228	727.0	COG1331@1|root,COG1331@2|Bacteria,2GJ88@201174|Actinobacteria,4CMYD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Protein of unknown function, DUF255	-	-	-	ko:K06888	-	-	-	-	ko00000	-	-	-	Thioredox_DsbH
BYD2_k127_405370_15	1229780.BN381_10316	2.62e-110	377.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,3UWHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_405370_16	1041522.MCOL_V201895	1.411e-109	364.0	COG2130@1|root,COG2130@2|Bacteria,2GKR8@201174|Actinobacteria,232K1@1762|Mycobacteriaceae	201174|Actinobacteria	S	NADP-dependent oxidoreductase	yfmJ	-	-	ko:K07119	-	-	-	-	ko00000	-	-	-	ADH_N_2,ADH_zinc_N
BYD2_k127_405370_38	1313172.YM304_19640	1.953e-59	218.0	COG0778@1|root,COG0778@2|Bacteria,2GW57@201174|Actinobacteria,4CN7W@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_405370_39	1313172.YM304_19630	2.88e-59	213.0	2BWZ3@1|root,33X4C@2|Bacteria,2H5EF@201174|Actinobacteria,4CN6H@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_405370_0	1229780.BN381_430072	0.0	1677.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,3UWBK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA polymerase alpha chain like domain	dnaE	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
BYD2_k127_405370_58	1121413.JMKT01000016_gene73	0.0004233	54.0	COG2199@1|root,COG2202@1|root,COG2202@2|Bacteria,COG3706@2|Bacteria,1R7HC@1224|Proteobacteria,42SWJ@68525|delta/epsilon subdivisions,2X86E@28221|Deltaproteobacteria,2MHCD@213115|Desulfovibrionales	28221|Deltaproteobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_4,PAS_9,SBP_bac_3
BYD2_k127_405370_43	1120934.KB894415_gene3908	6.731e-44	166.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4E2RM@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2587
BYD2_k127_405370_10	1229780.BN381_430074	2.69e-125	420.0	COG1524@1|root,COG1524@2|Bacteria,2GISU@201174|Actinobacteria,3UWWP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Type I phosphodiesterase / nucleotide pyrophosphatase	-	-	-	-	-	-	-	-	-	-	-	-	Phosphodiest
BYD2_k127_405370_34	1313172.YM304_19590	3.716e-65	226.0	COG1959@1|root,COG1959@2|Bacteria,2HG5V@201174|Actinobacteria,4CN2Q@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
BYD2_k127_405370_50	33898.JRHJ01000048_gene7865	8.971e-35	149.0	COG1520@1|root,COG1520@2|Bacteria,2ICNU@201174|Actinobacteria	201174|Actinobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
BYD2_k127_405370_23	1313172.YM304_19580	1.764e-85	295.0	COG0564@1|root,COG0564@2|Bacteria,2GIY1@201174|Actinobacteria,4CN1X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
BYD2_k127_405370_52	1229780.BN381_430079	7.602e-29	129.0	COG0597@1|root,COG0597@2|Bacteria,2GKRX@201174|Actinobacteria,3UWUA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	MU	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	GO:0006464,GO:0006497,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0019538,GO:0034645,GO:0036211,GO:0040007,GO:0042157,GO:0042158,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044419,GO:0051704,GO:0071704,GO:1901564,GO:1901566,GO:1901576	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
BYD2_k127_405370_51	1229780.BN381_430080	8.314e-33	147.0	COG1734@1|root,COG1734@2|Bacteria	2|Bacteria	T	zinc ion binding	dksA	-	-	ko:K06204	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000,ko03009,ko03021	-	-	-	zf-dskA_traR
BYD2_k127_405370_1	1380390.JIAT01000009_gene1982	0.0	1090.0	COG0060@1|root,COG0060@2|Bacteria,2GK9M@201174|Actinobacteria,4CP6P@84995|Rubrobacteria	84995|Rubrobacteria	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
BYD2_k127_405370_57	106370.Francci3_1423	0.0002279	53.0	COG3599@1|root,COG3599@2|Bacteria,2GMSC@201174|Actinobacteria,4ET2B@85013|Frankiales	201174|Actinobacteria	D	PFAM DivIVA family protein	wag31	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030312,GO:0031647,GO:0040007,GO:0042546,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050821,GO:0051128,GO:0060187,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	-	-	-	-	-	-	-	-	-	DivIVA
BYD2_k127_405370_55	316056.RPC_0057	3.761e-07	55.0	COG0762@1|root,COG0762@2|Bacteria,1N73Q@1224|Proteobacteria,2UFZR@28211|Alphaproteobacteria,3JZGE@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	YGGT family	MA20_25225	-	-	ko:K02221	-	-	-	-	ko00000,ko02044	-	-	-	YGGT
BYD2_k127_405370_47	1229780.BN381_140002	1.66e-39	155.0	COG1799@1|root,COG1799@2|Bacteria,2GNVH@201174|Actinobacteria,3UWTH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA	sepF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
BYD2_k127_405370_41	1313172.YM304_19520	3.442e-52	192.0	COG0325@1|root,COG0325@2|Bacteria,2HGAF@201174|Actinobacteria,4CN9H@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Alanine racemase, N-terminal domain	-	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
BYD2_k127_405370_42	1229780.BN381_140005	2.625e-45	168.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,3UW88@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
BYD2_k127_4062936_0	1120950.KB892777_gene737	1.258e-151	496.0	COG0737@1|root,COG0737@2|Bacteria,2HFJ5@201174|Actinobacteria,4DVDK@85009|Propionibacteriales	201174|Actinobacteria	F	5'-nucleotidase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C
BYD2_k127_4064812_21	710421.Mycch_2953	2.416e-32	126.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2341M@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4064812_2	298654.FraEuI1c_6988	2.122e-180	599.0	COG2159@1|root,COG2159@2|Bacteria,2GKAB@201174|Actinobacteria,4ETXR@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_4064812_6	1206731.BAGB01000166_gene799	2.778e-133	449.0	COG1804@1|root,COG1804@2|Bacteria,2GRB0@201174|Actinobacteria,4FW2K@85025|Nocardiaceae	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
BYD2_k127_4064812_9	44454.NF84_09985	1.91e-116	388.0	COG2124@1|root,COG2124@2|Bacteria,2HSPE@201174|Actinobacteria,2353U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome P-450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_4064812_19	419947.MRA_1952	1.199e-50	181.0	COG2337@1|root,COG2337@2|Bacteria,2IMGQ@201174|Actinobacteria,23B5D@1762|Mycobacteriaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	mazF5	GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
BYD2_k127_4064812_22	419947.MRA_1953	3.505e-26	114.0	2FDS3@1|root,345T0@2|Bacteria,2GUMT@201174|Actinobacteria,23BJN@1762|Mycobacteriaceae	201174|Actinobacteria	S	Evidence 4 Homologs of previously reported genes of	-	GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007	-	-	-	-	-	-	-	-	-	-	VapB_antitoxin
BYD2_k127_4064812_8	37919.EP51_30525	1.158e-125	442.0	COG0661@1|root,COG0661@2|Bacteria,2I6RY@201174|Actinobacteria,4FX8T@85025|Nocardiaceae	201174|Actinobacteria	S	ABC1 family	-	-	-	-	-	-	-	-	-	-	-	-	ABC1
BYD2_k127_4064812_10	571166.KI421510_gene180	3.245e-113	378.0	COG1960@1|root,COG1960@2|Bacteria,1MVJC@1224|Proteobacteria,2TTRD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA dehydrogenase	MA20_06720	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_4064812_20	55952.BU52_23600	1.518e-35	142.0	COG1309@1|root,COG1309@2|Bacteria,2GMPD@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K22107	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
BYD2_k127_4064812_7	479433.Caci_5895	5.316e-131	427.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_4064812_23	103733.JNYO01000035_gene2980	6.097e-26	121.0	COG3468@1|root,COG3468@2|Bacteria,2GNAR@201174|Actinobacteria,4E004@85010|Pseudonocardiales	201174|Actinobacteria	MU	TIGRFAM LPXTG-motif cell wall anchor domain	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor,TED
BYD2_k127_4064812_16	285535.JOEY01000043_gene1274	1.826e-68	235.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
BYD2_k127_4064812_18	1229780.BN381_20007	1.003e-50	192.0	COG1545@1|root,COG1545@2|Bacteria,2GJHW@201174|Actinobacteria	201174|Actinobacteria	I	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
BYD2_k127_4064812_3	235985.BBPN01000019_gene5995	5.628e-155	500.0	COG0183@1|root,COG0183@2|Bacteria,2GNCM@201174|Actinobacteria,2NH7P@228398|Streptacidiphilus	201174|Actinobacteria	I	lipid-transfer protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
BYD2_k127_4064812_1	749414.SBI_01085	3.452e-196	627.0	COG0183@1|root,COG0183@2|Bacteria,2GJ0W@201174|Actinobacteria	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	ltp3	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
BYD2_k127_4064812_14	208439.AJAP_26860	2.375e-77	286.0	COG1028@1|root,COG1028@2|Bacteria,2GJGM@201174|Actinobacteria,4DYN3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.53	ko:K00038	ko00140,ko01100,map00140,map01100	-	R04831,R04834,R04844,R04847	RC00139,RC01219,RC01220	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
BYD2_k127_4064812_13	1380390.JIAT01000009_gene960	1.324e-94	342.0	COG0809@1|root,COG0809@2|Bacteria,2GN51@201174|Actinobacteria,4CSIA@84995|Rubrobacteria	84995|Rubrobacteria	J	Queuosine biosynthesis protein	-	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
BYD2_k127_4064812_15	1120934.KB894408_gene4824	1.751e-76	264.0	COG1028@1|root,COG1028@2|Bacteria,2HGA2@201174|Actinobacteria,4E2M4@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_4064812_17	1123023.JIAI01000014_gene3696	1.017e-56	220.0	COG2197@1|root,COG2197@2|Bacteria,2GJKM@201174|Actinobacteria,4E3G7@85010|Pseudonocardiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_4064812_12	1380390.JIAT01000009_gene957	9.286e-103	348.0	COG3850@1|root,COG3850@2|Bacteria,2GIWI@201174|Actinobacteria,4CU6T@84995|Rubrobacteria	201174|Actinobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	GAF_2,HATPase_c,HisKA_3
BYD2_k127_4064812_5	1229780.BN381_310036	2.768e-135	439.0	COG4638@1|root,COG4638@2|Bacteria,2IA3C@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
BYD2_k127_4064812_11	1122182.KB903833_gene5518	1.484e-108	365.0	COG3599@1|root,COG3599@2|Bacteria,2I2UK@201174|Actinobacteria,4D9JS@85008|Micromonosporales	201174|Actinobacteria	D	regulation of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
BYD2_k127_4064812_4	1136417.AZWE01000005_gene4552	1.619e-150	498.0	COG2141@1|root,COG2141@2|Bacteria,2GIY3@201174|Actinobacteria,4DBBX@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_4064812_0	1003195.SCAT_0704	1.223e-303	941.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,2GJ11@201174|Actinobacteria	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	GDC-P
BYD2_k127_4067189_4	706587.Desti_3650	7.941e-113	379.0	COG0161@1|root,COG0161@2|Bacteria,1MU2N@1224|Proteobacteria,42MFC@68525|delta/epsilon subdivisions,2WJ4H@28221|Deltaproteobacteria,2MQ47@213462|Syntrophobacterales	28221|Deltaproteobacteria	H	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor	bioA	-	2.6.1.62	ko:K00833	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R03231	RC00006,RC00887	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	AAA_26,Aminotran_3
BYD2_k127_4067189_6	1123319.AUBE01000004_gene668	3.046e-73	259.0	COG0697@1|root,COG0697@2|Bacteria,2I198@201174|Actinobacteria	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
BYD2_k127_4067189_3	882083.SacmaDRAFT_0454	4.044e-114	388.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria,4E363@85010|Pseudonocardiales	201174|Actinobacteria	Q	Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_4067189_11	330084.JNYZ01000011_gene7176	2.089e-24	121.0	COG4636@1|root,COG4636@2|Bacteria,2IGTR@201174|Actinobacteria,4E2US@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
BYD2_k127_4067189_9	290397.Adeh_1286	7.536e-47	187.0	COG0454@1|root,COG0456@2|Bacteria,1RD40@1224|Proteobacteria,43EF3@68525|delta/epsilon subdivisions,2X0ID@28221|Deltaproteobacteria,2Z1N2@29|Myxococcales	28221|Deltaproteobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_4067189_8	525909.Afer_1760	2.066e-52	205.0	COG2177@1|root,COG2177@2|Bacteria,2GJMA@201174|Actinobacteria,4CN4Q@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Part of the ABC transporter FtsEX involved in cellular division	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	-
BYD2_k127_4067189_5	1229780.BN381_80108	8.22e-106	347.0	COG2884@1|root,COG2884@2|Bacteria,2GJE1@201174|Actinobacteria,3UW73@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	ATPases associated with a variety of cellular activities	ftsE	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
BYD2_k127_4067189_2	1229780.BN381_80107	1.035e-124	409.0	COG1186@1|root,COG1186@2|Bacteria,2GJ0F@201174|Actinobacteria,3UW7K@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
BYD2_k127_4067189_0	1229780.BN381_80106	0.0	1257.0	COG0653@1|root,COG0653@2|Bacteria,2GIRT@201174|Actinobacteria,3UW8Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
BYD2_k127_4067189_12	1123386.AUIW01000010_gene68	5.611e-16	86.0	28TIQ@1|root,2ZFSJ@2|Bacteria,1WK1S@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4067189_10	1313172.YM304_28380	8.988e-25	117.0	COG1040@1|root,COG1040@2|Bacteria	2|Bacteria	K	competence protein	comF	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pribosyltran
BYD2_k127_4067189_7	105420.BBPO01000029_gene6732	9.353e-54	207.0	COG2364@1|root,COG2364@2|Bacteria,2GKA1@201174|Actinobacteria,2NGFI@228398|Streptacidiphilus	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4067189_1	1394178.AWOO02000005_gene3590	2.874e-264	822.0	COG0499@1|root,COG0499@2|Bacteria,2GK2Q@201174|Actinobacteria,4EIAX@85012|Streptosporangiales	201174|Actinobacteria	H	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine	ahcY	GO:0000096,GO:0000098,GO:0000166,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009087,GO:0009116,GO:0009119,GO:0009987,GO:0016020,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0019899,GO:0022610,GO:0030260,GO:0030312,GO:0033353,GO:0034641,GO:0035375,GO:0035635,GO:0036094,GO:0040007,GO:0042278,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044273,GO:0044281,GO:0044282,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044650,GO:0046085,GO:0046128,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0048037,GO:0050662,GO:0051186,GO:0051287,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0055086,GO:0070403,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901657	3.3.1.1	ko:K01251	ko00270,ko01100,map00270,map01100	M00035	R00192,R04936	RC00056,RC00069,RC01161,RC01243	ko00000,ko00001,ko00002,ko01000,ko01009,ko04147	-	-	-	AdoHcyase,AdoHcyase_NAD
BYD2_k127_406980_3	96561.Dole_2360	5.417e-14	76.0	COG3356@1|root,COG3356@2|Bacteria,1QW1Q@1224|Proteobacteria,43BRP@68525|delta/epsilon subdivisions,2X72J@28221|Deltaproteobacteria,2MMRW@213118|Desulfobacterales	28221|Deltaproteobacteria	S	Neutral/alkaline non-lysosomal ceramidase, N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	Ceramidase_alk
BYD2_k127_406980_0	37919.EP51_21010	3.782e-124	406.0	COG0492@1|root,COG0492@2|Bacteria,2GIXN@201174|Actinobacteria,4FYCP@85025|Nocardiaceae	201174|Actinobacteria	O	pyridine nucleotide-disulfide oxidoreductase	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Methyltransf_25,Pyr_redox_2
BYD2_k127_406980_2	1463934.JOCF01000016_gene3794	5.798e-81	274.0	COG1396@1|root,COG1396@2|Bacteria,2GPWH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
BYD2_k127_406980_1	644283.Micau_4494	1.234e-88	299.0	COG0587@1|root,COG0587@2|Bacteria,2GJ1P@201174|Actinobacteria,4D8EW@85008|Micromonosporales	201174|Actinobacteria	L	DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase	dnaE2	GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496	2.7.7.7	ko:K14162	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
BYD2_k127_4074246_1	469383.Cwoe_3631	4.146e-107	360.0	COG0277@1|root,COG0277@2|Bacteria,2GKI9@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked oxidase	-	-	-	-	-	-	-	-	-	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_4074246_3	1229780.BN381_50059	1.309e-82	288.0	COG1316@1|root,COG1316@2|Bacteria,2GJJJ@201174|Actinobacteria,3UWX5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	LytR_C,LytR_cpsA_psr
BYD2_k127_4074246_0	1120936.KB907209_gene1722	2.23e-114	401.0	COG2038@1|root,COG2038@2|Bacteria,2GJ16@201174|Actinobacteria,4EG5Z@85012|Streptosporangiales	201174|Actinobacteria	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,DBI_PRT,Nitroreductase
BYD2_k127_4074246_2	1123251.ATWM01000001_gene894	4.967e-91	318.0	COG0079@1|root,COG0079@2|Bacteria,2I2ND@201174|Actinobacteria,4FG89@85021|Intrasporangiaceae	201174|Actinobacteria	E	Aminotransferase class I and II	cobC	GO:0008150,GO:0040007	2.6.1.9,4.1.1.81	ko:K00817,ko:K04720	ko00340,ko00350,ko00360,ko00400,ko00401,ko00860,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00860,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243,R06530	RC00006,RC00517,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2,CbiG_C
BYD2_k127_4074246_4	477641.MODMU_0642	5.196e-61	220.0	COG1270@1|root,COG1270@2|Bacteria,2GMB8@201174|Actinobacteria,4ES1Q@85013|Frankiales	201174|Actinobacteria	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
BYD2_k127_4086394_5	391037.Sare_4214	1.258e-81	296.0	COG2197@1|root,COG2197@2|Bacteria,2GIVA@201174|Actinobacteria,4D9AV@85008|Micromonosporales	201174|Actinobacteria	T	response regulator	tcsR3	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_4086394_4	471852.Tcur_4227	1.199e-83	303.0	COG1983@1|root,COG4585@1|root,COG1983@2|Bacteria,COG4585@2|Bacteria,2GJ4J@201174|Actinobacteria,4EG3Q@85012|Streptosporangiales	201174|Actinobacteria	KT	PspC domain	tcsS3	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HATPase_c_2,PspC
BYD2_k127_4086394_6	1123320.KB889688_gene463	3.999e-23	113.0	COG1983@1|root,COG1983@2|Bacteria,2GIVS@201174|Actinobacteria	201174|Actinobacteria	KT	PspC domain protein	pspC	-	-	-	-	-	-	-	-	-	-	-	DUF2154,PspC
BYD2_k127_4086394_3	1313172.YM304_15080	6.994e-102	340.0	2C8AG@1|root,33SQR@2|Bacteria,2H3BF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4086394_1	1313172.YM304_15060	2.44e-146	471.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4CMRJ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
BYD2_k127_4086394_8	1089544.KB912942_gene448	0.0001463	55.0	2EXFB@1|root,33QRR@2|Bacteria,2GRZU@201174|Actinobacteria,4E79C@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4086394_7	1121272.KB903258_gene5360	5.446e-20	106.0	COG1595@1|root,COG1595@2|Bacteria,2GWFT@201174|Actinobacteria,4DJEK@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_4086394_0	1313172.YM304_29640	1.73e-190	614.0	COG0320@1|root,COG0321@1|root,COG0320@2|Bacteria,COG0321@2|Bacteria,2GKD4@201174|Actinobacteria,4CMR4@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives	lipA	-	2.8.1.8	ko:K03644	ko00785,ko01100,map00785,map01100	-	R07767,R07768	RC01978	ko00000,ko00001,ko01000	-	-	-	BPL_LplA_LipB,LIAS_N,Radical_SAM
BYD2_k127_4086394_2	1313172.YM304_29650	4.539e-116	385.0	COG0508@1|root,COG0508@2|Bacteria,2GMUV@201174|Actinobacteria,4CMW0@84992|Acidimicrobiia	84992|Acidimicrobiia	C	e3 binding domain	-	-	2.3.1.61	ko:K00658	ko00020,ko00310,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R02570,R02571,R08549	RC00004,RC02727,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
BYD2_k127_4102050_2	525909.Afer_1846	9.736e-187	589.0	COG0459@1|root,COG0459@2|Bacteria,2GKC9@201174|Actinobacteria,4CNG0@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	-	-	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
BYD2_k127_4102050_12	1313172.YM304_23740	6.789e-35	143.0	COG0406@1|root,COG0406@2|Bacteria,2IAPP@201174|Actinobacteria	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
BYD2_k127_4102050_13	1382356.JQMP01000001_gene1284	8.52e-30	124.0	COG5349@1|root,COG5349@2|Bacteria,2G7FQ@200795|Chloroflexi,27ZAC@189775|Thermomicrobia	189775|Thermomicrobia	S	Protein of unknown function (DUF983)	-	-	-	-	-	-	-	-	-	-	-	-	DUF983
BYD2_k127_4102050_1	1313172.YM304_36020	1.02e-190	618.0	COG1073@1|root,COG1073@2|Bacteria,2I52S@201174|Actinobacteria	201174|Actinobacteria	S	alpha beta	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4102050_3	644283.Micau_2845	6.45e-149	484.0	COG2242@1|root,COG2242@2|Bacteria,2IAR0@201174|Actinobacteria,4D9FM@85008|Micromonosporales	201174|Actinobacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4102050_9	1150864.MILUP08_43219	1.794e-91	327.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
BYD2_k127_4102050_8	644283.Micau_2846	4.804e-95	341.0	COG3119@1|root,COG3119@2|Bacteria,2IDUS@201174|Actinobacteria,4DCI6@85008|Micromonosporales	201174|Actinobacteria	P	Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
BYD2_k127_4102050_10	1313172.YM304_04940	4.106e-91	306.0	COG1526@1|root,COG1526@2|Bacteria,2GKWC@201174|Actinobacteria,4CN5S@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH	fdhD	-	-	ko:K02379	-	-	-	-	ko00000	-	-	-	FdhD-NarQ
BYD2_k127_4102050_0	266117.Rxyl_0146	5.849e-263	829.0	COG0243@1|root,COG0243@2|Bacteria,2GJWZ@201174|Actinobacteria,4CQ1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdopterin,Molydop_binding
BYD2_k127_4102050_11	1229780.BN381_150097	6.893e-73	263.0	COG3253@1|root,COG3253@2|Bacteria	2|Bacteria	S	peroxidase activity	ywfI	-	-	ko:K00435	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R11522	RC00884	ko00000,ko00001,ko01000	-	-	-	Chlor_dismutase
BYD2_k127_4102050_6	526225.Gobs_3203	1.796e-112	378.0	COG0559@1|root,COG0559@2|Bacteria,2GMAY@201174|Actinobacteria,4ESA3@85013|Frankiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K11956	ko02010,ko02024,map02010,map02024	M00237,M00322	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.2,3.A.1.4.6	-	-	BPD_transp_2,CarboxypepD_reg
BYD2_k127_4102050_5	1048339.KB913029_gene4523	3.146e-115	379.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4EUKY@85013|Frankiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	livM	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_4102050_4	1122611.KB903962_gene4480	7.716e-123	402.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4EGR5@85012|Streptosporangiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_4102050_7	1146883.BLASA_2291	8.972e-105	362.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4EUWF@85013|Frankiales	201174|Actinobacteria	E	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	livF	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_4102050_14	1146883.BLASA_2290	2.161e-29	120.0	COG0683@1|root,COG0683@2|Bacteria,2GM00@201174|Actinobacteria,4EV7E@85013|Frankiales	201174|Actinobacteria	E	Receptor family ligand binding region	livK	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
BYD2_k127_4105738_2	1206720.BAFQ01000293_gene6383	1.343e-98	326.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4FUZE@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_4105738_1	298655.KI912266_gene5882	4.74e-99	335.0	COG1960@1|root,COG1960@2|Bacteria,2GMTN@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
BYD2_k127_4105738_0	298655.KI912266_gene5907	3.598e-126	437.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_4135996_0	65497.JODV01000031_gene1303	2.999e-233	752.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4E15N@85010|Pseudonocardiales	201174|Actinobacteria	P	E1-E2 ATPase	ctpE	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
BYD2_k127_4135996_1	1313172.YM304_07510	1.809e-215	696.0	COG3250@1|root,COG3250@2|Bacteria,2GM69@201174|Actinobacteria	201174|Actinobacteria	G	beta-mannosidase	csxA	GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005575,GO:0005576,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0016052,GO:0016787,GO:0016798,GO:0043170,GO:0044238,GO:0071704,GO:1901575	3.2.1.165,3.2.1.25	ko:K01192,ko:K15855	ko00511,ko00520,ko01100,ko04142,map00511,map00520,map01100,map04142	-	R01966	RC00049	ko00000,ko00001,ko01000	-	-	-	F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
BYD2_k127_4135996_4	1229780.BN381_60056	1.056e-48	181.0	COG1670@1|root,COG1670@2|Bacteria,2IS6V@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
BYD2_k127_4135996_3	1313172.YM304_07470	3.637e-77	267.0	28HIR@1|root,2Z7U4@2|Bacteria,2GN2S@201174|Actinobacteria	201174|Actinobacteria	S	succinate dehydrogenase	sdhC	-	-	ko:K00241	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002	-	-	-	Sdh_cyt
BYD2_k127_4135996_2	153721.MYP_1448	7.686e-162	528.0	COG1053@1|root,COG1053@2|Bacteria,4NFDU@976|Bacteroidetes,47JE5@768503|Cytophagia	976|Bacteroidetes	C	TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit	sdhA	-	1.3.5.1,1.3.5.4	ko:K00239	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
BYD2_k127_4152394_8	1209984.BN978_04746	1.471e-51	203.0	COG1363@1|root,COG1363@2|Bacteria,2ICG5@201174|Actinobacteria,235ZX@1762|Mycobacteriaceae	201174|Actinobacteria	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
BYD2_k127_4152394_1	164757.Mjls_2037	5.697e-226	739.0	COG0189@1|root,COG0454@1|root,COG0189@2|Bacteria,COG0456@2|Bacteria,2GN0U@201174|Actinobacteria,2356T@1762|Mycobacteriaceae	201174|Actinobacteria	HJK	acetyltransferase	cphA	-	6.3.2.29,6.3.2.30	ko:K03802	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Dala_Dala_lig_C,Mur_ligase_C,Mur_ligase_M,RimK
BYD2_k127_4152394_0	547163.BN979_03272	5.797e-291	902.0	COG0367@1|root,COG0367@2|Bacteria,2GJIM@201174|Actinobacteria,232RF@1762|Mycobacteriaceae	201174|Actinobacteria	E	Asparagine synthase	asnB_1	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
BYD2_k127_4152394_11	1449353.JQMQ01000005_gene2162	1.064e-41	164.0	COG2021@1|root,COG2021@2|Bacteria,2I2Z2@201174|Actinobacteria,2NF16@228398|Streptacidiphilus	201174|Actinobacteria	E	Ndr family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4,Abhydrolase_6,Hydrolase_4
BYD2_k127_4152394_4	1122609.AUGT01000013_gene4105	1.849e-109	385.0	COG2909@1|root,COG2909@2|Bacteria,2I50W@201174|Actinobacteria,4DPMG@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
BYD2_k127_4152394_9	1120797.KB908270_gene2930	2.529e-47	191.0	COG1403@1|root,COG1403@2|Bacteria,2HAHI@201174|Actinobacteria,234RM@1762|Mycobacteriaceae	201174|Actinobacteria	V	PFAM HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DUF222,HNH
BYD2_k127_4152394_12	33876.JNXY01000034_gene868	3.712e-30	130.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4DEI8@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	RibD_C
BYD2_k127_4152394_10	1121924.ATWH01000001_gene4430	1.208e-43	162.0	COG2315@1|root,COG2315@2|Bacteria,2I2W9@201174|Actinobacteria,4FQ8P@85023|Microbacteriaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_4152394_6	1120950.KB892750_gene6853	8.789e-66	228.0	29Z57@1|root,30M2Y@2|Bacteria,2HZ8W@201174|Actinobacteria,4DR8J@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4152394_7	666685.R2APBS1_3187	1e-54	195.0	COG5649@1|root,COG5649@2|Bacteria,1RGY3@1224|Proteobacteria,1SP5H@1236|Gammaproteobacteria,1X79K@135614|Xanthomonadales	135614|Xanthomonadales	S	Domain of unknown function (DU1801)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1801
BYD2_k127_4152394_5	37919.EP51_05580	7.523e-71	243.0	COG1733@1|root,COG1733@2|Bacteria,2IQNN@201174|Actinobacteria,4G185@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
BYD2_k127_4152394_3	37919.EP51_05585	2.777e-161	516.0	COG0604@1|root,COG0604@2|Bacteria,2GRJM@201174|Actinobacteria,4FW2I@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
BYD2_k127_4152394_2	1240349.ANGC01000013_gene468	2.182e-211	669.0	COG0209@1|root,COG0209@2|Bacteria,2GKX9@201174|Actinobacteria,4FWF5@85025|Nocardiaceae	201174|Actinobacteria	F	Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen	nrdJ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
BYD2_k127_4153195_2	1313172.YM304_27460	2.282e-61	218.0	COG0233@1|root,COG0233@2|Bacteria,2GJ9J@201174|Actinobacteria,4CN2Z@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
BYD2_k127_4153195_0	1229780.BN381_330053	7.492e-106	348.0	COG0528@1|root,COG0528@2|Bacteria,2GKWQ@201174|Actinobacteria,3UW78@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006225,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009163,GO:0009165,GO:0009185,GO:0009188,GO:0009193,GO:0009194,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0033862,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042455,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046048,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
BYD2_k127_4153195_1	1313172.YM304_27480	4.674e-78	269.0	COG0264@1|root,COG0264@2|Bacteria,2GK4M@201174|Actinobacteria,4CMXN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
BYD2_k127_4179564_1	1348663.KCH_55830	1.773e-66	235.0	COG5587@1|root,COG5587@2|Bacteria,2IJG5@201174|Actinobacteria,2M2HA@2063|Kitasatospora	201174|Actinobacteria	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
BYD2_k127_4179564_0	1489678.RDMS_02435	1.202e-284	917.0	COG0210@1|root,COG0210@2|Bacteria,1WI0I@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	L	PFAM UvrD REP helicase	uvrD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DUF3553,UvrD-helicase,UvrD_C
BYD2_k127_4179564_2	543632.JOJL01000034_gene5129	2.606e-60	220.0	COG1376@1|root,COG3409@1|root,COG1376@2|Bacteria,COG3409@2|Bacteria,2GXGF@201174|Actinobacteria,4DINJ@85008|Micromonosporales	201174|Actinobacteria	M	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,YkuD
BYD2_k127_4179564_4	408672.NBCG_00715	2.861e-20	105.0	COG0741@1|root,COG0791@1|root,COG0741@2|Bacteria,COG0791@2|Bacteria,2IF18@201174|Actinobacteria,4DN6C@85009|Propionibacteriales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
BYD2_k127_4179564_5	1179773.BN6_59000	8.333e-05	55.0	COG5660@1|root,COG5660@2|Bacteria,2IHDZ@201174|Actinobacteria,4E4SE@85010|Pseudonocardiales	201174|Actinobacteria	S	integral membrane protein	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_4179564_3	335543.Sfum_0272	3.579e-28	122.0	COG1595@1|root,COG1595@2|Bacteria,1MX7T@1224|Proteobacteria,42V72@68525|delta/epsilon subdivisions,2WRHE@28221|Deltaproteobacteria,2MSA6@213462|Syntrophobacterales	28221|Deltaproteobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_4203053_2	561175.KB894093_gene3080	1.368e-07	63.0	2CT9V@1|root,32SSX@2|Bacteria,2GKR6@201174|Actinobacteria,4EK03@85012|Streptosporangiales	201174|Actinobacteria	S	Domain of unknown function (DUF4129)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
BYD2_k127_4203053_1	266940.Krad_3816	3.84e-17	93.0	COG5180@1|root,COG5180@2|Bacteria,2GKJ7@201174|Actinobacteria	201174|Actinobacteria	A	pathogenesis	-	-	-	-	-	-	-	-	-	-	-	-	GPDPase_memb
BYD2_k127_4203053_0	1313172.YM304_12290	8.432e-23	100.0	COG0500@1|root,COG0500@2|Bacteria,2I3YC@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_4227372_5	1229780.BN381_100090	3.018e-56	213.0	COG0723@1|root,COG0723@2|Bacteria,2I02M@201174|Actinobacteria	201174|Actinobacteria	C	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
BYD2_k127_4227372_3	1229780.BN381_100091	5.599e-89	329.0	COG0437@1|root,COG0437@2|Bacteria,2I2DV@201174|Actinobacteria	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_11
BYD2_k127_4227372_0	1229780.BN381_100092	0.0	1207.0	COG0243@1|root,COG0243@2|Bacteria,2GJCK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372,ko:K02567	ko00910,ko01120,map00910,map01120	M00529,M00530,M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
BYD2_k127_4227372_2	1229780.BN381_100093	3.626e-139	456.0	COG2223@1|root,COG2223@2|Bacteria,2ICXH@201174|Actinobacteria	201174|Actinobacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4227372_6	1229780.BN381_70129	2.586e-53	202.0	COG2345@1|root,COG2345@2|Bacteria,2GQ3A@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_4227372_1	1313172.YM304_18000	6.773e-167	536.0	COG0798@1|root,COG0798@2|Bacteria,2GJ4H@201174|Actinobacteria	201174|Actinobacteria	P	arsenical-resistance protein	arsB	-	1.20.4.1	ko:K03325,ko:K03741	-	-	-	-	ko00000,ko01000,ko02000	2.A.59	-	-	SBF
BYD2_k127_4227372_7	1236902.ANAS01000038_gene3087	9.333e-33	132.0	COG0640@1|root,COG0640@2|Bacteria,2IKNB@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
BYD2_k127_4227372_8	1283299.AUKG01000001_gene3106	3.242e-08	60.0	COG1366@1|root,COG1366@2|Bacteria,2HPDG@201174|Actinobacteria,4CQRG@84995|Rubrobacteria	84995|Rubrobacteria	T	STAS domain	-	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS
BYD2_k127_4227372_4	1089546.AQUI01000002_gene2956	2.301e-70	243.0	COG0431@1|root,COG0431@2|Bacteria,2GNFR@201174|Actinobacteria	201174|Actinobacteria	K	NAD(P)H-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
BYD2_k127_4230595_4	1229780.BN381_290120	1.19e-49	198.0	COG0078@1|root,COG0078@2|Bacteria,2GJ6H@201174|Actinobacteria,3UWID@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3,2.1.3.6	ko:K00611,ko:K13252	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
BYD2_k127_4230595_0	1229780.BN381_290121	1.952e-148	496.0	COG4992@1|root,COG4992@2|Bacteria,2GKE9@201174|Actinobacteria,3UW6N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Aminotransferase class-III	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
BYD2_k127_4230595_3	1313172.YM304_20800	1.165e-97	346.0	COG0548@1|root,COG0548@2|Bacteria,2GKDS@201174|Actinobacteria,4CMYC@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
BYD2_k127_4230595_2	1161401.ASJA01000022_gene125	1.523e-110	371.0	COG1364@1|root,COG1364@2|Bacteria,1MU0T@1224|Proteobacteria,2TS98@28211|Alphaproteobacteria,43W6I@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
BYD2_k127_4230595_1	1229780.BN381_290123	2.871e-130	424.0	COG0002@1|root,COG0002@2|Bacteria,2GKQK@201174|Actinobacteria,3UWGI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	GO:0000166,GO:0003674,GO:0005488,GO:0008150,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0070401,GO:0097159,GO:1901265,GO:1901363	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
BYD2_k127_4230595_5	1122933.JNIY01000003_gene1143	1.525e-31	128.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4F0PI@85016|Cellulomonadaceae	201174|Actinobacteria	J	Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily	pheT	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
BYD2_k127_4233606_2	591159.ACEZ01000155_gene4454	5.266e-34	145.0	COG0664@1|root,COG0664@2|Bacteria,2I8QQ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
BYD2_k127_4233606_1	1214101.BN159_4222	7.772e-46	178.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_4233606_0	710696.Intca_2645	7.62e-72	257.0	COG1835@1|root,COG1835@2|Bacteria,2GKI5@201174|Actinobacteria,4FI7P@85021|Intrasporangiaceae	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BYD2_k127_4235752_6	1214101.BN159_0570	5.062e-53	190.0	2BVXR@1|root,32IG2@2|Bacteria,2IMT1@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DoxX
BYD2_k127_4235752_4	1048339.KB913029_gene2693	1.83e-66	243.0	COG2345@1|root,COG2345@2|Bacteria,2HCEF@201174|Actinobacteria,4ESVJ@85013|Frankiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_4235752_1	1323361.JPOC01000073_gene3673	9.624e-148	482.0	COG0477@1|root,COG0477@2|Bacteria,2IIAH@201174|Actinobacteria,4FWIK@85025|Nocardiaceae	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_2,Sugar_tr
BYD2_k127_4235752_3	557599.MKAN_00560	1.385e-85	307.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin,Polyketide_cyc2
BYD2_k127_4235752_5	1157637.KB892114_gene4699	1.212e-62	222.0	COG1309@1|root,COG1309@2|Bacteria,2INX9@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4235752_0	2074.JNYD01000004_gene4948	3.472e-186	594.0	COG1653@1|root,COG1653@2|Bacteria,2IDWS@201174|Actinobacteria,4E16T@85010|Pseudonocardiales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
BYD2_k127_4235752_2	1121272.KB903249_gene2215	2.014e-120	393.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
BYD2_k127_4240289_14	345341.KUTG_09535	7.189e-09	66.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_4240289_16	1304865.JAGF01000001_gene1653	3.268e-06	56.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	int	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_4240289_15	543632.JOJL01000001_gene7856	7.271e-09	63.0	COG0169@1|root,COG0169@2|Bacteria,2IE53@201174|Actinobacteria	201174|Actinobacteria	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4240289_1	1125971.ASJB01000022_gene6914	9.066e-182	577.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4DXSS@85010|Pseudonocardiales	201174|Actinobacteria	S	hydrolase or acyltransferase of alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EHN
BYD2_k127_4240289_11	585529.HMPREF0291_11967	8.906e-22	100.0	COG0346@1|root,COG0346@2|Bacteria,2IQJB@201174|Actinobacteria,22NDD@1653|Corynebacteriaceae	201174|Actinobacteria	E	glyoxalase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_4240289_4	219305.MCAG_05351	7.604e-73	249.0	COG0406@1|root,COG0406@2|Bacteria,2IJ7S@201174|Actinobacteria,4DDQU@85008|Micromonosporales	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
BYD2_k127_4240289_6	1122622.ATWJ01000009_gene3390	1.494e-55	201.0	COG0053@1|root,COG0053@2|Bacteria,2GQJJ@201174|Actinobacteria,4FFVU@85021|Intrasporangiaceae	201174|Actinobacteria	P	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
BYD2_k127_4240289_7	469371.Tbis_0444	2.49e-44	164.0	COG0640@1|root,COG0640@2|Bacteria,2IKUI@201174|Actinobacteria,4E5R4@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Bacterial regulatory protein, arsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
BYD2_k127_4240289_10	153721.MYP_3119	7.213e-27	114.0	COG0262@1|root,COG0262@2|Bacteria,4NPX6@976|Bacteroidetes,47RPC@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C
BYD2_k127_4240289_5	365528.KB891275_gene699	9.842e-62	228.0	COG4759@1|root,COG4759@2|Bacteria	2|Bacteria	O	protein conserved in bacteria containing thioredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
BYD2_k127_4240289_2	35754.JNYJ01000030_gene7556	3.677e-141	496.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DBTA@85008|Micromonosporales	201174|Actinobacteria	L	UvrD-like helicase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD-helicase,UvrD_C_2
BYD2_k127_4240289_8	1056816.JAFQ01000004_gene6347	2.131e-43	175.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria,4FX60@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_4240289_9	426716.JOAJ01000002_gene2156	1.14e-41	168.0	COG1960@1|root,COG1960@2|Bacteria,2GMTN@201174|Actinobacteria,4FUQK@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
BYD2_k127_4240289_12	1380393.JHVP01000014_gene4842	8.207e-16	91.0	COG4585@1|root,COG4585@2|Bacteria,2GJKG@201174|Actinobacteria,4ETZM@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
BYD2_k127_4240289_13	1538295.JY96_09610	3.46e-10	69.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4240289_3	1120936.KB907212_gene5126	4.772e-109	366.0	COG1073@1|root,COG1073@2|Bacteria,2GJE5@201174|Actinobacteria,4EMGF@85012|Streptosporangiales	201174|Actinobacteria	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
BYD2_k127_4240289_0	106370.Francci3_0926	0.0	1482.0	COG1028@1|root,COG2070@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4EU82@85013|Frankiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
BYD2_k127_428744_4	1229780.BN381_170038	1.246e-17	89.0	2C2HI@1|root,345RC@2|Bacteria,2H8AE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_428744_3	351607.Acel_0901	1.416e-41	162.0	COG1579@1|root,COG1579@2|Bacteria,2GP84@201174|Actinobacteria,4ESKG@85013|Frankiales	201174|Actinobacteria	S	C4-type zinc ribbon domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944	-	ko:K07164	-	-	-	-	ko00000	-	-	-	zf-RING_7
BYD2_k127_428744_0	1229780.BN381_170040	1.432e-133	474.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria,3UW69@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	pon1	-	-	-	-	-	-	-	-	-	-	-	PASTA,Transgly,Transpeptidase
BYD2_k127_428744_1	1313172.YM304_41020	4.998e-93	346.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,4CNUE@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_428744_5	1343740.M271_00410	1.699e-12	78.0	COG0673@1|root,COG0673@2|Bacteria,2GKW0@201174|Actinobacteria	201174|Actinobacteria	C	Oxidoreductase	-	-	1.1.1.384	ko:K13327	ko00523,ko01130,map00523,map01130	M00801,M00802	R05526	RC00897	ko00000,ko00001,ko00002,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
BYD2_k127_428744_2	36809.MAB_2542	1.771e-51	208.0	COG3467@1|root,COG3467@2|Bacteria,2IG17@201174|Actinobacteria,238QA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_4308723_15	545697.HMPREF0216_02243	2.593e-05	48.0	COG1910@1|root,COG1910@2|Bacteria,1TRH3@1239|Firmicutes,24ATZ@186801|Clostridia,36GB8@31979|Clostridiaceae	186801|Clostridia	P	DNA binding domain, excisionase family	-	-	-	ko:K07219	-	-	-	-	ko00000	-	-	-	HTH_17,PBP_like
BYD2_k127_4308723_12	1313172.YM304_12170	1.554e-28	120.0	COG5552@1|root,COG5552@2|Bacteria,2IQKN@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized conserved protein (DUF2277)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2277
BYD2_k127_4308723_7	164757.Mjls_0681	1.889e-64	229.0	COG3871@1|root,COG3871@2|Bacteria,2IFC3@201174|Actinobacteria,238T2@1762|Mycobacteriaceae	201174|Actinobacteria	S	stress protein (general stress protein 26)	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_4308723_8	1048339.KB913029_gene541	5.893e-59	219.0	COG5483@1|root,COG5483@2|Bacteria,2IHSH@201174|Actinobacteria,4ESUT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
BYD2_k127_4308723_10	1223523.H340_24550	5.335e-56	211.0	COG0454@1|root,COG0456@2|Bacteria,2II3I@201174|Actinobacteria	201174|Actinobacteria	K	Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
BYD2_k127_4308723_0	298655.KI912266_gene5486	8.016e-144	469.0	COG0014@1|root,COG0014@2|Bacteria,2GISA@201174|Actinobacteria,4ERK4@85013|Frankiales	201174|Actinobacteria	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	GO:0003674,GO:0003824,GO:0004350,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016620,GO:0016903,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2427c	Aldedh
BYD2_k127_4308723_9	1209984.BN978_03770	3.001e-58	222.0	2APBU@1|root,31EE2@2|Bacteria,2IC5S@201174|Actinobacteria,23CPY@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4308723_11	1121946.AUAX01000032_gene481	1.88e-40	157.0	COG1595@1|root,COG1595@2|Bacteria,2GKFQ@201174|Actinobacteria,4DJ8I@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_4308723_1	1313172.YM304_23480	3.094e-122	410.0	COG0464@1|root,COG0464@2|Bacteria,2GJWA@201174|Actinobacteria,4CNTH@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA
BYD2_k127_4308723_13	1380347.JNII01000005_gene2984	1.67e-24	114.0	COG3247@1|root,COG3247@2|Bacteria,2HU0P@201174|Actinobacteria,4EW3F@85013|Frankiales	201174|Actinobacteria	S	Short repeat of unknown function (DUF308)	-	-	-	-	-	-	-	-	-	-	-	-	DUF308
BYD2_k127_4308723_4	314256.OG2516_17835	1.467e-98	335.0	COG3842@1|root,COG3842@2|Bacteria,1MU3I@1224|Proteobacteria,2TQQJ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10111,ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00204,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
BYD2_k127_4308723_5	1229780.BN381_20064	1.463e-82	304.0	COG1175@1|root,COG1175@2|Bacteria,2GKBJ@201174|Actinobacteria,3UX0T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K05814,ko:K10118	ko02010,map02010	M00196,M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.3	-	-	BPD_transp_1
BYD2_k127_4308723_6	1229780.BN381_20065	1.56e-67	247.0	COG0395@1|root,COG0395@2|Bacteria,2GMTH@201174|Actinobacteria,3UWR1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	COG0395 ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K05815	ko02010,map02010	M00198,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.3	-	-	BPD_transp_1
BYD2_k127_4308723_2	1229780.BN381_20066	2.512e-104	357.0	COG1653@1|root,COG1653@2|Bacteria,2HP0P@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
BYD2_k127_4308723_3	1229780.BN381_20066	8.782e-99	340.0	COG1653@1|root,COG1653@2|Bacteria,2HP0P@201174|Actinobacteria	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K05813	ko02010,map02010	M00198	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.3	-	-	SBP_bac_8
BYD2_k127_4308723_14	479434.Sthe_0078	9.321e-20	95.0	COG0477@1|root,COG0477@2|Bacteria,2G89T@200795|Chloroflexi,27Y75@189775|Thermomicrobia	189775|Thermomicrobia	P	Major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_4339334_0	298654.FraEuI1c_2875	7.625e-215	674.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria	201174|Actinobacteria	I	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
BYD2_k127_4339334_9	1229780.BN381_140044	1.264e-34	151.0	COG3688@1|root,COG3688@2|Bacteria	2|Bacteria	D	RNA-binding protein containing a PIN domain	yacP	-	-	ko:K06962	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_IV,GTP_EFTU,NYN_YacP
BYD2_k127_4339334_11	1229780.BN381_140045	6.086e-24	103.0	2ES7R@1|root,33JSG@2|Bacteria,2I1DU@201174|Actinobacteria,3UXPZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4339334_3	1229780.BN381_140046	2.366e-99	348.0	COG0322@1|root,COG2176@1|root,COG0322@2|Bacteria,COG2176@2|Bacteria,2GMC0@201174|Actinobacteria,3UWMB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	GIY-YIG type nucleases (URI domain)	dnaQ	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0016020,GO:0030312,GO:0032991,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071944,GO:1902494,GO:1905347,GO:1905348,GO:1990391	2.7.7.7	ko:K02342	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	GIY-YIG,RNase_T,UVR
BYD2_k127_4339334_12	570268.ANBB01000002_gene275	2.487e-22	113.0	COG1522@1|root,COG1522@2|Bacteria,2IQD4@201174|Actinobacteria,4EJZK@85012|Streptosporangiales	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
BYD2_k127_4339334_15	208439.AJAP_40150	1.343e-10	71.0	COG1309@1|root,COG1309@2|Bacteria,2GP2Z@201174|Actinobacteria,4E3DK@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
BYD2_k127_4339334_4	1131814.JAFO01000001_gene2372	5.742e-94	321.0	COG0547@1|root,COG0547@2|Bacteria,1MUPV@1224|Proteobacteria,2TR8S@28211|Alphaproteobacteria,3EYYC@335928|Xanthobacteraceae	28211|Alphaproteobacteria	F	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
BYD2_k127_4339334_13	1229780.BN381_170006	1.088e-21	99.0	2CC1Y@1|root,32YV9@2|Bacteria,2HGFB@201174|Actinobacteria,3UXMX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Transcription factor WhiB	-	-	-	-	-	-	-	-	-	-	-	-	Whib
BYD2_k127_4339334_6	1229780.BN381_170007	1.917e-64	226.0	COG0247@1|root,COG0247@2|Bacteria,2GVNV@201174|Actinobacteria	201174|Actinobacteria	C	Protein of unknown function (DUF3501)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3501
BYD2_k127_4339334_2	1121877.JQKF01000010_gene732	5.431e-139	456.0	COG0247@1|root,COG0247@2|Bacteria,2HGN8@201174|Actinobacteria,4CNP8@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG
BYD2_k127_4339334_5	1121877.JQKF01000010_gene733	9.478e-72	246.0	COG1592@1|root,COG1592@2|Bacteria,2HH04@201174|Actinobacteria,4CP0H@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Rubrerythrin	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4339334_8	1229780.BN381_170009	2.369e-42	164.0	COG0735@1|root,COG0735@2|Bacteria,2IFBR@201174|Actinobacteria,3UWZ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Ferric uptake regulator family	catR	-	-	ko:K22297	-	-	-	-	ko00000,ko03000	-	-	-	FUR
BYD2_k127_4339334_7	1463900.JOIX01000006_gene784	3.804e-44	186.0	COG0372@1|root,COG0372@2|Bacteria,2GM3G@201174|Actinobacteria	201174|Actinobacteria	C	Citrate synthase	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt,HTH_17
BYD2_k127_4339334_14	110319.CF8_0103	1.003e-12	81.0	COG0561@1|root,COG0561@2|Bacteria,2GP42@201174|Actinobacteria,4DR0A@85009|Propionibacteriales	201174|Actinobacteria	J	hydrolases of the HAD superfamily	cof	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
BYD2_k127_4339334_1	1229780.BN381_170034	5.148e-174	563.0	COG0578@1|root,COG0578@2|Bacteria,2GJKN@201174|Actinobacteria,3UWFB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family	-	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,DAO_C
BYD2_k127_4339334_10	1229780.BN381_170035	3.54e-26	117.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_4358584_4	1313172.YM304_37010	2.554e-44	178.0	2DE9Z@1|root,32U2Z@2|Bacteria,2ID6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4358584_0	1229780.BN381_250070	8.463e-249	796.0	COG1643@1|root,COG1643@2|Bacteria,2GMAW@201174|Actinobacteria,3UX3A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	ATP-dependent helicase C-terminal	hrpB	-	3.6.4.13	ko:K03579	-	-	-	-	ko00000,ko01000	-	-	-	DEAD,HA2,Helicase_C,HrpB_C
BYD2_k127_4358584_5	713587.THITH_11295	2.446e-18	87.0	COG3360@1|root,COG3360@2|Bacteria,1N6YT@1224|Proteobacteria,1SJ4Y@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Dodecin	-	-	-	ko:K09165	-	-	-	-	ko00000	-	-	-	Dodecin
BYD2_k127_4358584_1	164757.Mjls_4258	4.141e-102	356.0	COG1960@1|root,COG1960@2|Bacteria,2IAIE@201174|Actinobacteria,237ZZ@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	fadE35	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M
BYD2_k127_4358584_2	471853.Bcav_2971	7.869e-63	225.0	COG1898@1|root,COG1898@2|Bacteria	2|Bacteria	M	dTDP-4-dehydrorhamnose 3,5-epimerase activity	rmlC	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind,dTDP_sugar_isom
BYD2_k127_4358584_3	1370125.AUWT01000023_gene5796	1.221e-60	222.0	COG2141@1|root,COG2141@2|Bacteria,2GMUE@201174|Actinobacteria,236IS@1762|Mycobacteriaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_4363697_4	665571.STHERM_c03960	7.807e-78	281.0	COG3345@1|root,COG3345@2|Bacteria,2J62F@203691|Spirochaetes	203691|Spirochaetes	G	Melibiase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
BYD2_k127_4363697_1	1382304.JNIL01000001_gene2932	2.582e-111	377.0	COG2272@1|root,COG2272@2|Bacteria,1UXY5@1239|Firmicutes,4HCKV@91061|Bacilli	91061|Bacilli	I	Belongs to the type-B carboxylesterase lipase family	pnbA	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
BYD2_k127_4363697_2	1461580.CCAS010000009_gene1253	3.504e-108	373.0	COG0235@1|root,COG0235@2|Bacteria,1TZDD@1239|Firmicutes,4HDVI@91061|Bacilli,1ZET4@1386|Bacillus	91061|Bacilli	G	Class II Aldolase and Adducin N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
BYD2_k127_4363697_5	471852.Tcur_2668	4.727e-30	137.0	COG5485@1|root,COG5485@2|Bacteria,2GMYI@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
BYD2_k127_4363697_0	326424.FRAAL4409	6.059e-152	494.0	COG2230@1|root,COG2230@2|Bacteria,2GJ94@201174|Actinobacteria,4ERPB@85013|Frankiales	201174|Actinobacteria	M	cyclopropane-fatty-acyl-phospholipid synthase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
BYD2_k127_4363697_3	1313172.YM304_25740	9.048e-100	332.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,4CMQS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Glycine cleavage T-protein C-terminal barrel domain	gcvT	-	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
BYD2_k127_4370160_6	515635.Dtur_0933	0.0005502	47.0	COG0559@1|root,COG0559@2|Bacteria	2|Bacteria	E	leucine import across plasma membrane	livH	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_4370160_3	1229780.BN381_80213	2.225e-98	332.0	COG3394@1|root,COG3394@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	3.5.1.105	ko:K03478	-	-	-	-	ko00000,ko01000	-	-	-	YdjC
BYD2_k127_4370160_5	1123321.KB905821_gene4307	2.473e-10	66.0	COG3255@1|root,COG3255@2|Bacteria,2GS4C@201174|Actinobacteria	201174|Actinobacteria	I	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
BYD2_k127_4370160_2	1229780.BN381_80211	6.1e-107	355.0	COG2120@1|root,COG2120@2|Bacteria,2H2NY@201174|Actinobacteria,3UWN4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	mca	GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657	3.5.1.115	ko:K18455	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
BYD2_k127_4370160_4	1229780.BN381_410019	5.074e-25	111.0	COG1585@1|root,COG1585@2|Bacteria	2|Bacteria	OU	cellular response to DNA damage stimulus	nfeD	-	-	ko:K07340	-	-	-	-	ko00000	-	-	-	NfeD
BYD2_k127_4370160_1	1229780.BN381_410018	2.87e-122	400.0	COG0330@1|root,COG0330@2|Bacteria,2GJ1U@201174|Actinobacteria,3UWHD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
BYD2_k127_4370160_0	1229780.BN381_80206	6.896e-131	423.0	COG3273@1|root,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PhoU,TrkA_C
BYD2_k127_4376304_22	479434.Sthe_1897	2.334e-16	92.0	COG1714@1|root,COG1714@2|Bacteria	2|Bacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
BYD2_k127_4376304_18	1449976.KALB_3233	1.528e-29	136.0	COG2199@1|root,COG2199@2|Bacteria,2I2FR@201174|Actinobacteria,4DYHC@85010|Pseudonocardiales	201174|Actinobacteria	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
BYD2_k127_4376304_10	40571.JOEA01000006_gene4382	5.555e-73	250.0	COG2229@1|root,COG2229@2|Bacteria,2GJIT@201174|Actinobacteria,4DXCN@85010|Pseudonocardiales	201174|Actinobacteria	S	ATP binding protein	-	-	-	ko:K06945	-	-	-	-	ko00000	-	-	-	ATP_bind_1
BYD2_k127_4376304_19	2074.JNYD01000012_gene439	2.516e-23	104.0	COG1846@1|root,COG1846@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	2.7.1.83	ko:K16328	ko00240,map00240	-	R03315	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	DUF3489,DUF742
BYD2_k127_4376304_16	1134445.AJJM01000123_gene2525	2.778e-37	147.0	COG2018@1|root,COG2018@2|Bacteria,2IFB7@201174|Actinobacteria	201174|Actinobacteria	S	Roadblock lc7 family protein	cvnB6	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
BYD2_k127_4376304_2	1123024.AUII01000010_gene787	1.168e-138	469.0	COG0840@1|root,COG4251@1|root,COG0840@2|Bacteria,COG4251@2|Bacteria,2GK6E@201174|Actinobacteria,4DX42@85010|Pseudonocardiales	201174|Actinobacteria	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	cvnA6	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_4376304_9	656024.FsymDg_4333	1.945e-78	276.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4ESC1@85013|Frankiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_4376304_8	369723.Strop_1133	8.762e-82	281.0	COG1396@1|root,COG1396@2|Bacteria,2IMDC@201174|Actinobacteria,4DEAS@85008|Micromonosporales	201174|Actinobacteria	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BYD2_k127_4376304_20	1127134.NOCYR_4008	3.889e-19	88.0	2E6IT@1|root,3315W@2|Bacteria	2|Bacteria	S	Domain of unknown function (DUF397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF397
BYD2_k127_4376304_3	1229780.BN381_80178	6.499e-124	406.0	COG3491@1|root,COG3491@2|Bacteria,2GT52@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the iron ascorbate-dependent oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy,DIOX_N
BYD2_k127_4376304_17	1205910.B005_1660	9.849e-37	158.0	2E376@1|root,32Y6Y@2|Bacteria,2H1QX@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4376304_6	356851.JOAN01000016_gene6181	3.637e-92	312.0	COG2755@1|root,COG2755@2|Bacteria,2I8JW@201174|Actinobacteria,4DDG5@85008|Micromonosporales	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
BYD2_k127_4376304_0	1229780.BN381_60071	3.717e-249	797.0	COG2366@1|root,COG2366@2|Bacteria,2GMDM@201174|Actinobacteria	201174|Actinobacteria	S	Penicillin amidase	aac	GO:0005575,GO:0005576	3.5.1.97	ko:K07116	-	-	-	-	ko00000,ko01000	-	-	-	Penicil_amidase
BYD2_k127_4376304_21	58123.JOFJ01000018_gene4299	9.449e-18	94.0	COG1309@1|root,COG1309@2|Bacteria,2IC64@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4376304_1	1122604.JONR01000009_gene2357	2.471e-158	519.0	COG3239@1|root,COG3239@2|Bacteria,1MW29@1224|Proteobacteria,1RPHS@1236|Gammaproteobacteria,1X48K@135614|Xanthomonadales	135614|Xanthomonadales	I	Fatty acid desaturase	-	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
BYD2_k127_4376304_12	73044.JNXP01000002_gene1967	3.487e-61	214.0	COG4405@1|root,COG4405@2|Bacteria,2IFEU@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
BYD2_k127_4376304_7	1283287.KB822583_gene2850	8.76e-90	302.0	COG3025@1|root,COG3025@2|Bacteria,2IN8R@201174|Actinobacteria	201174|Actinobacteria	S	triphosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
BYD2_k127_4376304_13	1298863.AUEP01000007_gene386	4.426e-44	161.0	2C6EM@1|root,2ZFYQ@2|Bacteria,2GXX8@201174|Actinobacteria	201174|Actinobacteria	S	YCII-related domain	-	-	-	ko:K09780	-	-	-	-	ko00000	-	-	-	YCII
BYD2_k127_4376304_4	525368.HMPREF0591_5722	1.862e-109	375.0	COG0657@1|root,COG0657@2|Bacteria,2GTEV@201174|Actinobacteria,232VN@1762|Mycobacteriaceae	201174|Actinobacteria	I	esterase	lipO	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
BYD2_k127_4376304_14	1123023.JIAI01000002_gene4796	2.027e-43	166.0	COG2764@1|root,COG2764@2|Bacteria,2IFK2@201174|Actinobacteria,4ECD8@85010|Pseudonocardiales	201174|Actinobacteria	S	Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_4376304_11	1123320.KB889562_gene6757	5.923e-67	243.0	COG2207@1|root,COG2207@2|Bacteria,2GK7C@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_4376304_5	1380393.JHVP01000006_gene3915	1.78e-106	353.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria,4ETQ9@85013|Frankiales	201174|Actinobacteria	S	PFAM ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
BYD2_k127_4376304_15	1313172.YM304_23520	9.352e-43	168.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,4CMU1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
BYD2_k127_4377117_1	469371.Tbis_0684	1.049e-163	526.0	COG1816@1|root,COG1816@2|Bacteria,2GJ6I@201174|Actinobacteria,4DZ10@85010|Pseudonocardiales	201174|Actinobacteria	F	PFAM Adenosine AMP deaminase	add	GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iNJ661.Rv3313c	A_deaminase
BYD2_k127_4377117_19	1123024.AUII01000027_gene2652	4.52e-25	109.0	COG2445@1|root,COG2445@2|Bacteria	2|Bacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
BYD2_k127_4377117_14	1146883.BLASA_4180	1.672e-35	139.0	COG1669@1|root,COG1669@2|Bacteria,2H5WE@201174|Actinobacteria	201174|Actinobacteria	S	nucleotidyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4377117_8	2074.JNYD01000007_gene1997	3.875e-72	265.0	COG3214@1|root,COG3214@2|Bacteria,2HMGZ@201174|Actinobacteria,4E46J@85010|Pseudonocardiales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
BYD2_k127_4377117_11	1123322.KB904634_gene2425	1.002e-53	196.0	COG5516@1|root,COG5516@2|Bacteria,2GP70@201174|Actinobacteria	201174|Actinobacteria	S	Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
BYD2_k127_4377117_2	390989.JOEG01000003_gene4602	7.456e-151	482.0	COG0274@1|root,COG0274@2|Bacteria,2GJIR@201174|Actinobacteria,4DADZ@85008|Micromonosporales	201174|Actinobacteria	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
BYD2_k127_4377117_0	471853.Bcav_0209	2.622e-267	844.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_4377117_3	1120950.KB892785_gene251	2.443e-132	438.0	COG1012@1|root,COG1012@2|Bacteria,2GKSN@201174|Actinobacteria,4DNA7@85009|Propionibacteriales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_4377117_13	870187.Thini_1988	2.25e-37	154.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631,DUF2510,PknH_C,TIR_2
BYD2_k127_4377117_10	1463825.JNXC01000024_gene5054	3.919e-58	228.0	28PC1@1|root,2ZC4I@2|Bacteria,2ID9Q@201174|Actinobacteria,4E0ZU@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4231
BYD2_k127_4377117_20	1313421.JHBV01000043_gene2983	2.992e-22	109.0	COG0657@1|root,COG0657@2|Bacteria,4NNWF@976|Bacteroidetes	976|Bacteroidetes	I	COG0657 Esterase lipase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase,Lipase_GDSL_2,Peptidase_S9
BYD2_k127_4377117_23	331869.BAL199_10657	2.322e-05	55.0	COG0664@1|root,COG0664@2|Bacteria,1RI6M@1224|Proteobacteria,2U9WH@28211|Alphaproteobacteria,4BQJM@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	K	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cNMP_binding
BYD2_k127_4377117_21	1172180.KB911798_gene6508	3.716e-13	77.0	COG1246@1|root,COG1246@2|Bacteria,2GJQ8@201174|Actinobacteria	201174|Actinobacteria	E	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_4377117_16	1123023.JIAI01000001_gene6471	8.43e-33	134.0	COG1309@1|root,COG1309@2|Bacteria,2HR0A@201174|Actinobacteria,4E3IU@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K18939	-	M00715	-	-	ko00000,ko00002,ko03000	-	-	-	TetR_C_13,TetR_N
BYD2_k127_4377117_6	28444.JODQ01000006_gene662	6.363e-101	342.0	COG1533@1|root,COG1533@2|Bacteria,2GM31@201174|Actinobacteria,4EFX2@85012|Streptosporangiales	201174|Actinobacteria	L	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
BYD2_k127_4377117_7	469383.Cwoe_0229	3.761e-99	332.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4CRR7@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
BYD2_k127_4377117_17	388051.AUFE01000026_gene5216	1.424e-27	119.0	COG2329@1|root,COG2329@2|Bacteria,1QTY7@1224|Proteobacteria,2WGHG@28216|Betaproteobacteria,1KIEA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_4377117_9	1116369.KB890024_gene3188	1.829e-59	210.0	COG2020@1|root,COG2020@2|Bacteria,1RBJE@1224|Proteobacteria,2U6NI@28211|Alphaproteobacteria,43PG5@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	O	Isoprenylcysteine carboxyl methyltransferase (ICMT) family	-	-	-	-	-	-	-	-	-	-	-	-	PEMT
BYD2_k127_4377117_5	1280949.HAD_00915	1.732e-103	349.0	COG2159@1|root,COG2159@2|Bacteria,1MVTS@1224|Proteobacteria,2VGQX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_4377117_18	1120936.KB907217_gene3589	9.904e-26	116.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria,4EJE7@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4377117_12	1313172.YM304_04540	9.799e-52	199.0	COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4CNV2@84992|Acidimicrobiia	84992|Acidimicrobiia	K	MerR, DNA binding	-	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind
BYD2_k127_4377117_4	450851.PHZ_c1001	4.216e-124	410.0	COG1680@1|root,COG1680@2|Bacteria,1MVPR@1224|Proteobacteria,2TRWZ@28211|Alphaproteobacteria,2KFVB@204458|Caulobacterales	204458|Caulobacterales	V	beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_4377117_15	1394178.AWOO02000070_gene325	4.624e-34	134.0	COG1643@1|root,COG1643@2|Bacteria,2GIWX@201174|Actinobacteria,4EGY7@85012|Streptosporangiales	201174|Actinobacteria	L	Helicase associated domain (HA2)  Add an annotation	hrpA	-	3.6.4.13	ko:K03578	-	-	-	-	ko00000,ko01000	-	-	-	AAA_19,DEAD,DUF3418,HA2,Helicase_C,OB_NTP_bind
BYD2_k127_4428816_0	1229780.BN381_190004	1.153e-48	190.0	COG1247@1|root,COG1247@2|Bacteria,2IHSY@201174|Actinobacteria,3UXM9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	yncA	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_4
BYD2_k127_4428816_1	525909.Afer_0396	2.031e-17	83.0	COG0050@1|root,COG0050@2|Bacteria,2GK4T@201174|Actinobacteria,4CMSE@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
BYD2_k127_4468895_1	1313172.YM304_39270	6.94e-24	102.0	COG0247@1|root,COG2181@1|root,COG0247@2|Bacteria,COG2181@2|Bacteria,2GJ7M@201174|Actinobacteria,4CMWD@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_8
BYD2_k127_4468895_2	1120948.KB903243_gene2305	8.721e-06	57.0	2C2NP@1|root,334Y5@2|Bacteria,2IDXP@201174|Actinobacteria,4E42Q@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4468895_0	1380354.JIAN01000005_gene1911	1.727e-55	213.0	COG1361@1|root,COG1595@1|root,COG1361@2|Bacteria,COG1595@2|Bacteria,2GJFK@201174|Actinobacteria,4F277@85016|Cellulomonadaceae	201174|Actinobacteria	K	TIGRFAM RNA polymerase sigma factor, sigma-70 family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,zf-HC2
BYD2_k127_4483399_1	743718.Isova_0286	9.54e-81	273.0	COG0717@1|root,COG0717@2|Bacteria,2GKQQ@201174|Actinobacteria,4F3FX@85017|Promicromonosporaceae	201174|Actinobacteria	F	2'-deoxycytidine 5'-triphosphate deaminase (DCD)	dcd	GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD
BYD2_k127_4483399_3	1121946.AUAX01000035_gene6183	1.047e-14	83.0	2AZYG@1|root,31S8E@2|Bacteria,2GQD7@201174|Actinobacteria,4DEZ7@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4483399_0	1246995.AFR_27325	6.577e-103	337.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616,Exo_endo_phos
BYD2_k127_4483399_5	284031.JNXD01000060_gene1404	1.756e-06	53.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616,Exo_endo_phos
BYD2_k127_4483399_2	1246995.AFR_27325	3.168e-21	96.0	COG2374@1|root,COG2374@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF3616,Exo_endo_phos
BYD2_k127_4525471_2	1229780.BN381_510008	5.399e-96	330.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_4525471_5	298655.KI912267_gene6905	7.155e-36	147.0	COG1309@1|root,COG1309@2|Bacteria,2ICIZ@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4525471_4	1303692.SFUL_2259	1.033e-65	233.0	COG3087@1|root,COG3087@2|Bacteria,2I7WV@201174|Actinobacteria	201174|Actinobacteria	D	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
BYD2_k127_4525471_0	743718.Isova_2485	2.258e-108	373.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4F3WI@85017|Promicromonosporaceae	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_4525471_3	1463820.JOGW01000026_gene4973	2.034e-89	308.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_4525471_1	1463820.JOGW01000026_gene4972	2.006e-100	342.0	COG4585@1|root,COG4585@2|Bacteria,2I9E9@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
BYD2_k127_4525471_6	1343740.M271_49435	2.834e-26	112.0	COG1574@1|root,COG1574@2|Bacteria,2GKXR@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
BYD2_k127_4535750_5	402881.Plav_0570	6.088e-118	391.0	COG0318@1|root,COG0318@2|Bacteria,1MUIC@1224|Proteobacteria,2U3CV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_4535750_23	1078020.KEK_09202	4.854e-26	116.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria,235WU@1762|Mycobacteriaceae	201174|Actinobacteria	S	Nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
BYD2_k127_4535750_4	1078020.KEK_09197	1.007e-136	467.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,237UH@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C
BYD2_k127_4535750_7	1229780.BN381_100028	8.261e-100	353.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
BYD2_k127_4535750_27	1211815.CBYP010000067_gene175	3.316e-18	100.0	COG1309@1|root,COG1309@2|Bacteria,2HS05@201174|Actinobacteria,4EVYD@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
BYD2_k127_4535750_9	1137269.AZWL01000019_gene4155	1.471e-84	291.0	COG1576@1|root,COG3832@1|root,COG1576@2|Bacteria,COG3832@2|Bacteria,2I3MI@201174|Actinobacteria	201174|Actinobacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,MDMPI_N
BYD2_k127_4535750_22	369723.Strop_2047	3.601e-39	157.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4DF02@85008|Micromonosporales	201174|Actinobacteria	K	transcriptional regulators	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_4535750_6	2074.JNYD01000005_gene3309	2.687e-107	352.0	COG4312@1|root,COG4312@2|Bacteria,2GIVC@201174|Actinobacteria,4E2Q4@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
BYD2_k127_4535750_10	478741.JAFS01000001_gene2211	1.366e-76	272.0	COG1225@1|root,COG1225@2|Bacteria,46SWU@74201|Verrucomicrobia,37GJJ@326457|unclassified Verrucomicrobia	74201|Verrucomicrobia	O	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
BYD2_k127_4535750_3	1172188.KB911820_gene2445	4.523e-154	509.0	COG2403@1|root,COG2403@2|Bacteria,2IF9H@201174|Actinobacteria,4FEFF@85021|Intrasporangiaceae	201174|Actinobacteria	S	cyclic 2,3-diphosphoglycerate synthetase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4535750_2	58123.JOFJ01000003_gene2165	2.081e-170	579.0	COG0616@1|root,COG0616@2|Bacteria,2HQDG@201174|Actinobacteria,4EHD6@85012|Streptosporangiales	201174|Actinobacteria	OU	Peptidase family S49	sppA	-	-	ko:K04773,ko:K04774	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S49
BYD2_k127_4535750_20	1454010.JEOE01000001_gene760	1.413e-49	180.0	COG0346@1|root,COG0346@2|Bacteria,2IFMD@201174|Actinobacteria,4F2NU@85016|Cellulomonadaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4535750_13	1194972.MVAC_12718	1.72e-72	259.0	COG0662@1|root,COG0662@2|Bacteria,2I41N@201174|Actinobacteria,2380V@1762|Mycobacteriaceae	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_4535750_25	1173020.Cha6605_6178	1.506e-19	104.0	COG1846@1|root,COG1846@2|Bacteria,1G8VK@1117|Cyanobacteria	1117|Cyanobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BYD2_k127_4535750_26	633147.Olsu_0691	1.064e-18	99.0	COG0477@1|root,COG2814@2|Bacteria,2HUI3@201174|Actinobacteria,4CUSE@84998|Coriobacteriia	84998|Coriobacteriia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_4535750_18	1292034.OR37_00526	5.449e-54	199.0	COG1409@1|root,COG1409@2|Bacteria,1QI4K@1224|Proteobacteria,2TV5Q@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
BYD2_k127_4535750_15	1206733.BAGC01000112_gene6831	2.158e-65	236.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4G069@85025|Nocardiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
BYD2_k127_4535750_14	1068978.AMETH_2343	3.292e-67	239.0	COG1946@1|root,COG1946@2|Bacteria,2GMZB@201174|Actinobacteria,4E0QA@85010|Pseudonocardiales	201174|Actinobacteria	I	Thioesterase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
BYD2_k127_4535750_1	1206744.BAGL01000032_gene18	1.199e-306	959.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4FXX6@85025|Nocardiaceae	201174|Actinobacteria	C	Molydopterin dinucleotide binding domain	-	-	1.17.1.9	ko:K00122	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
BYD2_k127_4535750_11	67352.JODS01000004_gene5892	3.02e-76	270.0	COG4106@1|root,COG4106@2|Bacteria,2GK0K@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase	metZ	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_4535750_21	356851.JOAN01000015_gene2716	1.889e-41	158.0	COG5516@1|root,COG5516@2|Bacteria,2GJZN@201174|Actinobacteria,4D9ZQ@85008|Micromonosporales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
BYD2_k127_4535750_17	471852.Tcur_2587	7.713e-57	206.0	COG1024@1|root,COG1024@2|Bacteria,2GJDK@201174|Actinobacteria,4EGMR@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_4535750_24	1504822.CCNO01000008_gene2093	1.652e-24	117.0	COG0631@1|root,COG0631@2|Bacteria,2NR1Q@2323|unclassified Bacteria	2|Bacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	BofC_C,PP2C,PP2C_2
BYD2_k127_4535750_0	471852.Tcur_1775	0.0	1021.0	COG1523@1|root,COG1523@2|Bacteria,2GJ00@201174|Actinobacteria,4EFWY@85012|Streptosporangiales	201174|Actinobacteria	G	Carbohydrate-binding module 48 (Isoamylase N-terminal domain)	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
BYD2_k127_4535750_16	1229172.JQFA01000002_gene3850	3.326e-60	224.0	COG0642@1|root,COG2205@2|Bacteria,1G17B@1117|Cyanobacteria,1H8KR@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_4535750_19	1487953.JMKF01000072_gene3616	4.937e-52	203.0	COG0642@1|root,COG2205@2|Bacteria,1G17B@1117|Cyanobacteria,1H8KR@1150|Oscillatoriales	1117|Cyanobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_4535750_8	1240349.ANGC01000009_gene2817	6.505e-89	305.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4FZ7X@85025|Nocardiaceae	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_4535750_12	1211815.CBYP010000050_gene637	9.728e-73	261.0	COG3173@1|root,COG3173@2|Bacteria,2I4D0@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_4542837_9	1229780.BN381_130338	1.896e-37	155.0	COG2852@1|root,COG2852@2|Bacteria	2|Bacteria	L	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
BYD2_k127_4542837_5	1120950.KB892709_gene4149	4.041e-132	447.0	COG1132@1|root,COG1132@2|Bacteria,2GMZI@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_4542837_6	1120950.KB892709_gene4148	1.464e-115	407.0	COG1132@1|root,COG1132@2|Bacteria,2GMZI@201174|Actinobacteria,4DPSI@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
BYD2_k127_4542837_0	1122939.ATUD01000003_gene3348	4.227e-288	906.0	COG0243@1|root,COG0243@2|Bacteria,2GNYQ@201174|Actinobacteria,4CR1R@84995|Rubrobacteria	84995|Rubrobacteria	C	Molybdopterin oxidoreductase Fe4S4 domain	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
BYD2_k127_4542837_1	479435.Kfla_2107	1.186e-224	737.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2IAS1@201174|Actinobacteria,4DWMF@85009|Propionibacteriales	201174|Actinobacteria	K	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,TPR_12,Trans_reg_C
BYD2_k127_4542837_7	1229780.BN381_10202	1.115e-91	316.0	COG2222@1|root,COG2222@2|Bacteria,2HGM1@201174|Actinobacteria,3UXD9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Bacterial phospho-glucose isomerase C-terminal SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS,bact-PGI_C
BYD2_k127_4542837_11	1229780.BN381_10201	8.333e-22	112.0	COG2835@1|root,COG2835@2|Bacteria	2|Bacteria	EG	tetraacyldisaccharide 4'-kinase activity	-	-	-	ko:K09791	-	-	-	-	ko00000	-	-	-	Trm112p
BYD2_k127_4542837_3	1121877.JQKF01000008_gene665	1.469e-167	538.0	COG1109@1|root,COG1109@2|Bacteria,2GJQA@201174|Actinobacteria,4CMU2@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	-	-	5.4.2.8	ko:K01840	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114	R01818	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
BYD2_k127_4542837_8	1229780.BN381_130002	1.815e-87	303.0	COG1215@1|root,COG1215@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_4542837_2	1229780.BN381_10199	1.511e-191	641.0	COG5617@1|root,COG5617@2|Bacteria,2H32H@201174|Actinobacteria	201174|Actinobacteria	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4542837_10	1313172.YM304_28510	1.021e-36	148.0	COG1266@1|root,COG1266@2|Bacteria,2H0BD@201174|Actinobacteria,4CNBE@84992|Acidimicrobiia	84992|Acidimicrobiia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
BYD2_k127_4542837_4	1313172.YM304_28530	2.237e-150	486.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
BYD2_k127_4552669_2	1229780.BN381_160023	6.409e-43	161.0	COG0838@1|root,COG0838@2|Bacteria,2IKWT@201174|Actinobacteria,3UXDH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoA	-	1.6.5.3	ko:K00330	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q4
BYD2_k127_4552669_0	1313172.YM304_35640	1.379e-86	292.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CMXA@84992|Acidimicrobiia	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoB	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
BYD2_k127_4552669_1	1313172.YM304_35630	1.129e-60	225.0	COG0852@1|root,COG0852@2|Bacteria,2GNVP@201174|Actinobacteria	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain	nuoC2	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
BYD2_k127_456596_3	1313172.YM304_20430	5.977e-54	197.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4CN9W@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
BYD2_k127_456596_2	1229780.BN381_50138	5.807e-68	236.0	COG2065@1|root,COG2065@2|Bacteria,2GJNP@201174|Actinobacteria,3UWP5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant	pyrR	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	2.4.2.9	ko:K02825	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000,ko03000	-	-	-	Pribosyltran
BYD2_k127_456596_5	67281.JNZZ01000006_gene5465	3.059e-12	78.0	COG1670@1|root,COG1670@2|Bacteria,2HYD5@201174|Actinobacteria,41C6S@629295|Streptomyces griseus group	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
BYD2_k127_456596_4	1120948.KB903240_gene3941	4.34e-23	113.0	COG0781@1|root,COG0781@2|Bacteria,2IM3D@201174|Actinobacteria,4E3S8@85010|Pseudonocardiales	201174|Actinobacteria	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	GO:0008150,GO:0040007	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
BYD2_k127_456596_1	1121877.JQKF01000024_gene2404	8.714e-81	273.0	COG0231@1|root,COG0231@2|Bacteria,2GJMS@201174|Actinobacteria,4CMZZ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
BYD2_k127_456596_0	247156.NFA_36330	1.04e-88	304.0	COG0006@1|root,COG0006@2|Bacteria,2GM7D@201174|Actinobacteria,4FUMT@85025|Nocardiaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	pepQ	GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564	3.4.11.9,3.4.13.9	ko:K01262,ko:K01271	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Peptidase_M24
BYD2_k127_4588979_2	768671.ThimaDRAFT_4597	6.517e-27	127.0	COG2133@1|root,COG3055@1|root,COG2133@2|Bacteria,COG3055@2|Bacteria,1R0C0@1224|Proteobacteria,1SE9B@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4588979_4	401053.AciPR4_0169	3.159e-07	63.0	COG4409@1|root,COG4409@2|Bacteria,3Y2GG@57723|Acidobacteria,2JI5J@204432|Acidobacteriia	204432|Acidobacteriia	G	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	ASH,DUF1573
BYD2_k127_4588979_0	298655.KI912266_gene3831	3.591e-39	167.0	COG1807@1|root,COG1807@2|Bacteria	2|Bacteria	M	4-amino-4-deoxy-L-arabinose transferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
BYD2_k127_4588979_1	1380390.JIAT01000010_gene4531	1.658e-27	125.0	COG0500@1|root,COG2226@2|Bacteria,2HWAV@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_4593754_0	404589.Anae109_4239	3.802e-90	335.0	COG0654@1|root,COG0654@2|Bacteria,1R03K@1224|Proteobacteria,43CQQ@68525|delta/epsilon subdivisions,2X7Y6@28221|Deltaproteobacteria,2Z1K0@29|Myxococcales	28221|Deltaproteobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
BYD2_k127_4593754_1	1121952.ATXT01000011_gene3025	2.216e-85	316.0	COG2909@1|root,COG3710@1|root,COG3899@1|root,COG2909@2|Bacteria,COG3710@2|Bacteria,COG3899@2|Bacteria,2GJAR@201174|Actinobacteria,4FMKW@85023|Microbacteriaceae	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
BYD2_k127_4593754_2	330214.NIDE0407	2.556e-84	293.0	COG0155@1|root,COG0425@1|root,COG0155@2|Bacteria,COG0425@2|Bacteria,3J11D@40117|Nitrospirae	40117|Nitrospirae	C	Nitrite and sulphite reductase 4Fe-4S domain	-	-	1.7.1.15,1.8.7.1	ko:K00362,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00530	R00787,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	NIR_SIR,NIR_SIR_ferr
BYD2_k127_4598337_7	1313172.YM304_38110	5.107e-139	457.0	COG1009@1|root,COG2111@1|root,COG1009@2|Bacteria,COG2111@2|Bacteria,2GIT4@201174|Actinobacteria,4CMPU@84992|Acidimicrobiia	201174|Actinobacteria	CP	protein synonym multiple resistance and pH homeostasis protein A	-	-	1.6.5.3	ko:K00341,ko:K05565,ko:K14086	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000,ko02000	2.A.63.1,2.A.63.2,3.D.1	-	-	DUF4040,MnhB,NADHdh,Proton_antipo_M,Proton_antipo_N
BYD2_k127_4598337_3	1229780.BN381_80237	2.874e-172	547.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_4598337_1	1229780.BN381_80236	5.634e-227	716.0	COG0318@1|root,COG0318@2|Bacteria,2GJA2@201174|Actinobacteria,3UXSB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	6.2.1.42	ko:K18688	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_4598337_21	1229780.BN381_30044	6.448e-44	173.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,3UWW3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
BYD2_k127_4598337_20	1122611.KB903970_gene2642	2.25e-44	168.0	COG1392@1|root,COG1392@2|Bacteria,2GJME@201174|Actinobacteria,4EGZ9@85012|Streptosporangiales	201174|Actinobacteria	P	Protein of unknown function DUF47	-	-	-	ko:K07220	-	-	-	-	ko00000	-	-	-	PhoU_div
BYD2_k127_4598337_9	1379698.RBG1_1C00001G0364	1.226e-116	384.0	COG0306@1|root,COG0306@2|Bacteria,2NP4R@2323|unclassified Bacteria	2|Bacteria	P	Phosphate transporter family	pit	-	-	ko:K03306	-	-	-	-	ko00000	2.A.20	-	-	PHO4
BYD2_k127_4598337_8	1313172.YM304_15550	3.655e-119	392.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,4CMRY@84992|Acidimicrobiia	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_4598337_30	1120958.AULD01000005_gene1929	1.22e-09	63.0	2E5R2@1|root,330FN@2|Bacteria,2GSXB@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4598337_26	1120958.AULD01000005_gene1928	6.039e-31	125.0	COG4113@1|root,COG4113@2|Bacteria,2GR4U@201174|Actinobacteria,4FQIB@85023|Microbacteriaceae	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
BYD2_k127_4598337_16	1440053.JOEI01000019_gene595	2.97e-72	268.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_4598337_23	644283.Micau_3569	1.969e-36	145.0	COG1309@1|root,COG1309@2|Bacteria,2IEU9@201174|Actinobacteria,4DCCF@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4598337_28	1463820.JOGW01000017_gene4137	1.182e-22	113.0	COG4319@1|root,COG4319@2|Bacteria,2GNV0@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_3
BYD2_k127_4598337_18	1048339.KB913029_gene592	7.216e-54	206.0	COG2267@1|root,COG2267@2|Bacteria,2GQDD@201174|Actinobacteria,4EVNM@85013|Frankiales	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_4598337_11	1229780.BN381_80226	2.035e-97	331.0	COG2887@1|root,COG2887@2|Bacteria,2GJC5@201174|Actinobacteria,3UWVT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	recB	-	-	ko:K07465	-	-	-	-	ko00000	-	-	-	PDDEXK_1
BYD2_k127_4598337_25	1313172.YM304_15490	1.313e-31	141.0	COG0671@1|root,COG0671@2|Bacteria,2HGAE@201174|Actinobacteria,4CN9F@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acid phosphatase homologues	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
BYD2_k127_4598337_15	710111.FraQA3DRAFT_2748	2.074e-76	261.0	COG1651@1|root,COG1651@2|Bacteria,2IT6U@201174|Actinobacteria	201174|Actinobacteria	O	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
BYD2_k127_4598337_19	40571.JOEA01000039_gene4644	7.718e-46	184.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4DX5D@85010|Pseudonocardiales	201174|Actinobacteria	KLT	PFAM Protein kinase domain	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
BYD2_k127_4598337_22	1121017.AUFG01000001_gene3096	1.285e-36	151.0	COG3132@1|root,COG4106@1|root,COG3132@2|Bacteria,COG4106@2|Bacteria,2I5BV@201174|Actinobacteria	201174|Actinobacteria	E	Protein of unknown function, DUF480	-	-	-	ko:K09915	-	-	-	-	ko00000	-	-	-	DUF480,Methyltransf_25
BYD2_k127_4598337_10	1229780.BN381_80222	1.297e-107	359.0	COG0076@1|root,COG2141@1|root,COG0076@2|Bacteria,COG2141@2|Bacteria,2GK3J@201174|Actinobacteria,3UWS0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	tdcA	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
BYD2_k127_4598337_14	929712.KI912613_gene1696	3.757e-84	291.0	COG4221@1|root,COG4221@2|Bacteria,2I2DY@201174|Actinobacteria,4CQ02@84995|Rubrobacteria	84995|Rubrobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_4598337_0	1380387.JADM01000002_gene2155	4.403e-243	777.0	28IUR@1|root,2Z8TE@2|Bacteria,1NW7C@1224|Proteobacteria,1RP4W@1236|Gammaproteobacteria,1XNCE@135619|Oceanospirillales	135619|Oceanospirillales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4598337_12	28444.JODQ01000010_gene3171	8.698e-89	302.0	COG0583@1|root,COG0583@2|Bacteria,2I9HH@201174|Actinobacteria,4EGQQ@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BYD2_k127_4598337_17	298655.KI912266_gene5090	1.829e-68	243.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_4598337_33	1463879.JOHP01000024_gene4079	7.641e-08	66.0	COG0500@1|root,COG2226@2|Bacteria,2GP9N@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_4598337_27	1380347.JNII01000005_gene3347	4.148e-29	135.0	COG3663@1|root,COG3663@2|Bacteria,2GNS5@201174|Actinobacteria,4ESR4@85013|Frankiales	201174|Actinobacteria	L	PFAM Uracil-DNA glycosylase superfamily	mug	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
BYD2_k127_4598337_4	570268.ANBB01000058_gene4272	6.056e-160	514.0	COG2015@1|root,COG2015@2|Bacteria,2H3T3@201174|Actinobacteria,4EJ4K@85012|Streptosporangiales	201174|Actinobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_dimr,Lactamase_B
BYD2_k127_4598337_24	1120936.KB907209_gene1768	6.239e-32	133.0	COG0586@1|root,COG0586@2|Bacteria,2HKKQ@201174|Actinobacteria,4EIYT@85012|Streptosporangiales	201174|Actinobacteria	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
BYD2_k127_4598337_6	1229780.BN381_80218	6.131e-144	462.0	COG2141@1|root,COG2141@2|Bacteria,2GN4N@201174|Actinobacteria	201174|Actinobacteria	C	PFAM Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_4598337_13	1229780.BN381_80217	1.188e-86	319.0	COG1946@1|root,COG1946@2|Bacteria	2|Bacteria	I	acyl-CoA hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT_3
BYD2_k127_4598337_5	1229780.BN381_80216	1.021e-156	537.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
BYD2_k127_4598337_32	1173023.KE650771_gene4421	5.175e-09	60.0	COG2261@1|root,COG2261@2|Bacteria,1G9AW@1117|Cyanobacteria,1JIZI@1189|Stigonemataceae	1117|Cyanobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
BYD2_k127_4598337_2	1313172.YM304_15410	6.378e-195	614.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,4CMTJ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_4598337_29	1122602.ATXP01000001_gene1100	1.378e-17	89.0	COG1525@1|root,COG1525@2|Bacteria,2GRK1@201174|Actinobacteria,1W9K7@1268|Micrococcaceae	201174|Actinobacteria	L	Staphylococcal nuclease homologues	-	-	3.1.31.1	ko:K01174,ko:K07038	-	-	-	-	ko00000,ko01000	-	-	-	Excalibur,SNase
BYD2_k127_4603133_11	1137269.AZWL01000001_gene5573	8.391e-08	59.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_4603133_2	1229780.BN381_80287	1.361e-170	545.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,3UW7X@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II/IV secretion system protein	cpaF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
BYD2_k127_4603133_6	1229780.BN381_80286	1.807e-73	273.0	COG4965@1|root,COG4965@2|Bacteria,2I3KW@201174|Actinobacteria,3UWVZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Type II secretion system (T2SS), protein F	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
BYD2_k127_4603133_7	1229780.BN381_80285	8.634e-72	255.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,3UWZJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
BYD2_k127_4603133_8	222534.KB893717_gene2176	7.34e-58	219.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
BYD2_k127_4603133_4	1313172.YM304_24100	1.17e-119	398.0	COG1159@1|root,COG1159@2|Bacteria,2GJJE@201174|Actinobacteria,4CN3C@84992|Acidimicrobiia	84992|Acidimicrobiia	J	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
BYD2_k127_4603133_3	1463881.KL591012_gene4981	6.484e-124	425.0	COG1199@1|root,COG1199@2|Bacteria,2GKT8@201174|Actinobacteria	201174|Actinobacteria	KL	helicase	dinG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	3.6.4.12	ko:K03722	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,Helicase_C_2
BYD2_k127_4603133_0	1380354.JIAN01000009_gene3733	4.332e-242	824.0	COG1074@1|root,COG1074@2|Bacteria,2GNKH@201174|Actinobacteria	201174|Actinobacteria	L	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
BYD2_k127_4603133_1	1380356.JNIK01000017_gene2900	8.369e-191	635.0	COG3857@1|root,COG3857@2|Bacteria,2I6QC@201174|Actinobacteria	201174|Actinobacteria	L	PD-(D/E)XK nuclease superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_1
BYD2_k127_4603133_10	469383.Cwoe_3429	3.39e-23	113.0	COG1295@1|root,COG1295@2|Bacteria	2|Bacteria	S	lipopolysaccharide transmembrane transporter activity	-	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
BYD2_k127_4603133_5	1121877.JQKF01000022_gene2271	4.71e-110	360.0	COG0020@1|root,COG0020@2|Bacteria,2GIXF@201174|Actinobacteria,4CN13@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	-	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
BYD2_k127_4603133_9	1229780.BN381_330106	1.083e-52	197.0	COG1381@1|root,COG1381@2|Bacteria,2GK81@201174|Actinobacteria,3UWH5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in DNA repair and RecF pathway recombination	recO	GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
BYD2_k127_4605550_1	1313172.YM304_19130	1.435e-89	305.0	COG1600@1|root,COG1600@2|Bacteria,2HGVB@201174|Actinobacteria,4CNW5@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S double cluster binding domain	-	-	1.17.99.6	ko:K18979	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Fer4_16
BYD2_k127_4605550_0	1313172.YM304_19140	7.431e-135	439.0	COG0438@1|root,COG0438@2|Bacteria,2GM6D@201174|Actinobacteria,4CN28@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.346	ko:K13668	-	-	R11703,R11704	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_4616126_2	1211815.CBYP010000063_gene1912	7.666e-99	329.0	COG4770@1|root,COG4770@2|Bacteria,2GIZP@201174|Actinobacteria	201174|Actinobacteria	I	carboxylase	-	-	6.4.1.4	ko:K01968	ko00280,ko01100,map00280,map01100	M00036	R04138	RC00367,RC00942	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2
BYD2_k127_4616126_0	1211815.CBYP010000063_gene1911	1.456e-311	975.0	COG3185@1|root,COG3185@2|Bacteria,2GJNC@201174|Actinobacteria,4EU7X@85013|Frankiales	201174|Actinobacteria	E	Acyclic terpene utilisation family protein AtuA	-	-	-	-	-	-	-	-	-	-	-	-	AtuA
BYD2_k127_4616126_1	1229780.BN381_40022	4.527e-105	377.0	COG1960@1|root,COG1960@2|Bacteria,2GJ7S@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N,Thioesterase
BYD2_k127_4616126_5	298654.FraEuI1c_2878	1.025e-77	269.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	tetR7	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
BYD2_k127_4616126_3	1211815.CBYP010000063_gene1909	1.67e-97	332.0	28HG7@1|root,2Z7S3@2|Bacteria,2GMJK@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Wyosine base formation	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N,Wyosine_form
BYD2_k127_4616126_4	298654.FraEuI1c_2880	1.429e-95	332.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4ESJA@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_4616126_6	1313172.YM304_01440	2.947e-42	170.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria	201174|Actinobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
BYD2_k127_4630665_11	926560.KE387027_gene536	5.62e-60	220.0	COG1231@1|root,COG1231@2|Bacteria,1WJ0T@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	Flavin containing amine oxidoreductase	-	-	1.4.3.4	ko:K00274	ko00260,ko00330,ko00340,ko00350,ko00360,ko00380,ko00950,ko00982,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00330,map00340,map00350,map00360,map00380,map00950,map00982,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00135	R02173,R02382,R02529,R02532,R02613,R02908,R02919,R04025,R04300,R04674,R04890,R04893,R04894,R04907,R04908,R08346,R08347,R08348,R11354	RC00062,RC00160,RC00225,RC00676,RC00807,RC00808,RC01808,RC02226,RC02713	ko00000,ko00001,ko00002,ko01000	-	-	-	Amino_oxidase
BYD2_k127_4630665_2	1123024.AUII01000002_gene897	1.446e-129	429.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria,4DZ97@85010|Pseudonocardiales	201174|Actinobacteria	T	Stage II sporulation protein E (SpoIIE)	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,SpoIIE
BYD2_k127_4630665_9	298655.KI912266_gene3382	7.535e-63	224.0	COG1296@1|root,COG1296@2|Bacteria,2IKHA@201174|Actinobacteria	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
BYD2_k127_4630665_7	1894.JOER01000105_gene6295	1.345e-72	269.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria	201174|Actinobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
BYD2_k127_4630665_25	675635.Psed_4262	2.545e-05	56.0	COG1714@1|root,COG1714@2|Bacteria,2IN6K@201174|Actinobacteria,4EC9B@85010|Pseudonocardiales	201174|Actinobacteria	S	RDD family	-	-	-	-	-	-	-	-	-	-	-	-	RDD
BYD2_k127_4630665_24	794903.OPIT5_21285	7.478e-06	59.0	COG4586@1|root,COG4586@2|Bacteria,46TXF@74201|Verrucomicrobia,3K7IF@414999|Opitutae	2|Bacteria	S	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_4630665_15	1068980.ARVW01000001_gene1602	4.64e-42	169.0	COG1309@1|root,COG1309@2|Bacteria,2IM68@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4630665_17	1463856.JOHY01000001_gene479	4.859e-31	126.0	2B4SD@1|root,31XIT@2|Bacteria,2II69@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_4630665_14	1121017.AUFG01000015_gene2661	7.487e-46	171.0	COG3153@1|root,COG3153@2|Bacteria,2IKX0@201174|Actinobacteria,4FH23@85021|Intrasporangiaceae	201174|Actinobacteria	S	Acetyltransferase	-	-	-	ko:K03824	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
BYD2_k127_4630665_26	644966.Tmar_0494	0.0009972	48.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
BYD2_k127_4630665_12	479432.Sros_5383	2.971e-50	184.0	COG1595@1|root,COG3631@1|root,COG1595@2|Bacteria,COG3631@2|Bacteria,2GMRK@201174|Actinobacteria,4EGWJ@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_4630665_8	1068980.ARVW01000001_gene8134	3.271e-71	247.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4DZWN@85010|Pseudonocardiales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_4630665_6	105420.BBPO01000045_gene1075	1.168e-76	261.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria,2NJUF@228398|Streptacidiphilus	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_4630665_16	1095767.CAHD01000194_gene205	7.444e-42	160.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
BYD2_k127_4630665_19	1292020.H483_0109050	4.718e-18	90.0	2CSTQ@1|root,32SRW@2|Bacteria,2GTXN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4630665_20	1380393.JHVP01000004_gene401	8.116e-14	85.0	COG5416@1|root,COG5416@2|Bacteria,2HD5K@201174|Actinobacteria	201174|Actinobacteria	S	Lipopolysaccharide assembly protein A domain	-	-	-	-	-	-	-	-	-	-	-	-	LapA_dom
BYD2_k127_4630665_1	1961.JOAK01000003_gene1742	3.092e-209	660.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
BYD2_k127_4630665_0	1869.MB27_23030	2.711e-242	764.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
BYD2_k127_4630665_5	1120960.ATXG01000004_gene1704	4.214e-99	357.0	COG2909@1|root,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,4FTD5@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
BYD2_k127_4630665_4	1120960.ATXG01000004_gene1704	4.247e-109	387.0	COG2909@1|root,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria,4FTD5@85023|Microbacteriaceae	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
BYD2_k127_4630665_23	1120949.KB903328_gene8809	2.369e-08	57.0	2EIST@1|root,33CI4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4630665_22	1394178.AWOO02000004_gene2431	3.206e-11	72.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4EKGG@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4630665_3	1120950.KB892812_gene7083	7.217e-116	390.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria,4DRW9@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_4630665_13	1120950.KB892812_gene7084	2.501e-47	175.0	COG0590@1|root,COG0590@2|Bacteria,2INAI@201174|Actinobacteria,4DQQ8@85009|Propionibacteriales	201174|Actinobacteria	FJ	MafB19-like deaminase	-	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1
BYD2_k127_4630665_18	1120792.JAFV01000001_gene3378	5.369e-19	94.0	COG0454@1|root,COG0454@2|Bacteria,1RBP2@1224|Proteobacteria,2UDPX@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_4630665_10	1123320.KB889697_gene8849	1.93e-60	220.0	COG2050@1|root,COG2050@2|Bacteria,2IJ8E@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_4634731_14	1120950.KB892796_gene2243	2.234e-54	193.0	COG1192@1|root,COG1192@2|Bacteria,2ICWE@201174|Actinobacteria,4DSPB@85009|Propionibacteriales	201174|Actinobacteria	D	VirC1 protein	-	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
BYD2_k127_4634731_9	134676.ACPL_2298	6.994e-102	340.0	COG2141@1|root,COG2141@2|Bacteria,2IG7J@201174|Actinobacteria,4DKZK@85008|Micromonosporales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_4634731_6	47839.CCAU010000011_gene5318	1.449e-118	392.0	COG1237@1|root,COG1237@2|Bacteria,2I8H7@201174|Actinobacteria,23ACA@1762|Mycobacteriaceae	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
BYD2_k127_4634731_12	58123.JOFJ01000029_gene1157	2.288e-73	253.0	COG0500@1|root,COG2226@2|Bacteria,2H9G5@201174|Actinobacteria,4EJD1@85012|Streptosporangiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_4634731_5	1318628.MARLIPOL_02925	1.357e-120	433.0	COG1453@1|root,COG1453@2|Bacteria,1NIR6@1224|Proteobacteria,1T3EJ@1236|Gammaproteobacteria,466GD@72275|Alteromonadaceae	1236|Gammaproteobacteria	S	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
BYD2_k127_4634731_17	272134.KB731324_gene5861	6.958e-38	164.0	COG0664@1|root,COG0664@2|Bacteria	2|Bacteria	T	cyclic nucleotide binding	crp	-	-	ko:K10914	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
BYD2_k127_4634731_10	1134912.AJTV01000021_gene3010	1.061e-93	316.0	COG0543@1|root,COG0543@2|Bacteria,1R6QZ@1224|Proteobacteria,2V487@28211|Alphaproteobacteria,36ZQF@31993|Methylocystaceae	28211|Alphaproteobacteria	CH	Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
BYD2_k127_4634731_8	106370.Francci3_4497	8.216e-112	380.0	COG1941@1|root,COG1941@2|Bacteria,2GSPN@201174|Actinobacteria,4EU21@85013|Frankiales	201174|Actinobacteria	C	NADH ubiquinone oxidoreductase, 20 Kd subunit	-	-	1.12.1.2	ko:K18007	-	-	-	-	ko00000,ko01000	-	-	-	Oxidored_q6
BYD2_k127_4634731_2	743836.AYNA01000054_gene84	1.974e-169	542.0	COG3259@1|root,COG3259@2|Bacteria,1QUQ7@1224|Proteobacteria,2TYKR@28211|Alphaproteobacteria,36Z9G@31993|Methylocystaceae	28211|Alphaproteobacteria	C	Nickel-dependent hydrogenase	-	-	1.12.1.2	ko:K00436	-	-	R00700	-	ko00000,ko01000	-	-	-	NiFeSe_Hases
BYD2_k127_4634731_19	469371.Tbis_1857	1.476e-24	120.0	COG0680@1|root,COG0680@2|Bacteria,2IJ3P@201174|Actinobacteria,4E5EF@85010|Pseudonocardiales	201174|Actinobacteria	C	Hydrogenase maturation protease	-	-	-	ko:K03605	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	HycI
BYD2_k127_4634731_20	408672.NBCG_00751	4.086e-20	93.0	COG0778@1|root,COG0778@2|Bacteria,2I5BC@201174|Actinobacteria,4DSK6@85009|Propionibacteriales	201174|Actinobacteria	L	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1918
BYD2_k127_4634731_4	1209984.BN978_06070	9.332e-147	477.0	COG2267@1|root,COG3710@1|root,COG2267@2|Bacteria,COG3710@2|Bacteria,2I419@201174|Actinobacteria,234R8@1762|Mycobacteriaceae	201174|Actinobacteria	IK	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Trans_reg_C
BYD2_k127_4634731_25	525904.Tter_2546	2.94e-05	58.0	COG0589@1|root,COG0589@2|Bacteria,2NRGN@2323|unclassified Bacteria	2|Bacteria	T	PFAM UspA domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Usp
BYD2_k127_4634731_15	469371.Tbis_0837	2.996e-54	213.0	COG1544@1|root,COG1544@2|Bacteria,2IB6N@201174|Actinobacteria,4E3BW@85010|Pseudonocardiales	201174|Actinobacteria	J	Sigma 54 modulation/S30EA ribosomal protein C terminus	-	-	-	-	-	-	-	-	-	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
BYD2_k127_4634731_22	1297581.H919_09292	6.693e-19	102.0	COG1734@1|root,COG1734@2|Bacteria,1V6MF@1239|Firmicutes,4HEPK@91061|Bacilli,21WSK@150247|Anoxybacillus	91061|Bacilli	T	Prokaryotic dksA/traR C4-type zinc finger	yteA	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
BYD2_k127_4634731_23	471853.Bcav_0478	1.056e-13	76.0	2EH65@1|root,3351X@2|Bacteria,2GQUG@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1876)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876,DUF1918
BYD2_k127_4634731_18	525909.Afer_1128	3.262e-34	139.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
BYD2_k127_4634731_1	1298863.AUEP01000008_gene1242	7.488e-177	569.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4DTCF@85009|Propionibacteriales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.48	ko:K02182	-	-	-	-	ko00000,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_4634731_11	1298863.AUEP01000008_gene1241	3.854e-86	296.0	29ZNQ@1|root,30MP9@2|Bacteria,2IJUR@201174|Actinobacteria,4DUE8@85009|Propionibacteriales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_4634731_13	1122611.KB904007_gene7764	1.583e-71	252.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_4634731_16	243230.DR_1148	2.999e-48	177.0	COG0490@1|root,COG0490@2|Bacteria,1WJS3@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	P	regulatory, ligand-binding protein related to C-terminal domains of K channels	-	-	-	ko:K07228	-	-	-	-	ko00000	-	-	-	TrkA_C
BYD2_k127_4634731_7	100226.SCO5782	3.344e-112	381.0	COG0475@1|root,COG0475@2|Bacteria,2GJ69@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sodium hydrogen exchanger	-	-	-	ko:K03455	-	-	-	-	ko00000	2.A.37	-	-	Na_H_Exchanger
BYD2_k127_4634731_21	298655.KI912267_gene7606	1.734e-19	96.0	COG4843@1|root,COG4843@2|Bacteria	2|Bacteria	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179
BYD2_k127_4634731_3	749927.AMED_4776	7.969e-163	557.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4E0IZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
BYD2_k127_4634731_0	1120949.KB903294_gene4151	0.0	1306.0	COG3459@1|root,COG3459@2|Bacteria,2IAZ0@201174|Actinobacteria,4DHXT@85008|Micromonosporales	201174|Actinobacteria	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
BYD2_k127_4634731_24	926550.CLDAP_24490	1.066e-07	53.0	COG0395@1|root,COG0395@2|Bacteria	2|Bacteria	P	glycerophosphodiester transmembrane transport	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
BYD2_k127_4636953_12	1298863.AUEP01000013_gene4053	1.456e-18	93.0	COG0500@1|root,COG2226@2|Bacteria,2GUHW@201174|Actinobacteria,4DS9J@85009|Propionibacteriales	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_4636953_1	2002.JOEQ01000051_gene8312	3.254e-116	375.0	COG0262@1|root,COG0262@2|Bacteria,2GKX0@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_4636953_10	1123320.KB889665_gene1483	8.379e-36	141.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,CBM_2
BYD2_k127_4636953_8	1957.JODX01000001_gene5517	2.597e-39	157.0	COG0510@1|root,COG0510@2|Bacteria,2GMFN@201174|Actinobacteria	201174|Actinobacteria	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_4636953_13	1306174.JODP01000012_gene6206	3.368e-17	89.0	COG1670@1|root,COG1670@2|Bacteria,2INDG@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.82	ko:K00663	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Acetyltransf_3
BYD2_k127_4636953_5	398512.JQKC01000010_gene155	2.637e-48	187.0	COG2866@1|root,COG3942@1|root,COG5563@1|root,COG2866@2|Bacteria,COG3942@2|Bacteria,COG5563@2|Bacteria,1V9CS@1239|Firmicutes	1239|Firmicutes	E	Carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4636953_2	1120950.KB892750_gene6897	1.662e-103	340.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_4636953_7	101510.RHA1_ro07090	1.98e-39	153.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_4636953_4	1313172.YM304_06550	1.472e-48	187.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_4636953_3	1394178.AWOO02000009_gene4246	5.31e-98	331.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_4636953_9	1394178.AWOO02000009_gene4245	5.987e-36	141.0	COG1576@1|root,COG1576@2|Bacteria	2|Bacteria	J	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
BYD2_k127_4636953_11	543632.JOJL01000017_gene9935	9.11e-30	126.0	COG5587@1|root,COG5587@2|Bacteria	2|Bacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
BYD2_k127_4636953_6	543632.JOJL01000017_gene9935	2.25e-40	160.0	COG5587@1|root,COG5587@2|Bacteria	2|Bacteria	S	PFAM conserved	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
BYD2_k127_4636953_0	543632.JOJL01000011_gene6846	6.528e-183	586.0	COG3547@1|root,COG3547@2|Bacteria,2IDDB@201174|Actinobacteria	201174|Actinobacteria	L	Transposase and inactivated derivatives	tnp3512a	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
BYD2_k127_4650671_1	35754.JNYJ01000037_gene4668	3.246e-209	682.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4DBBC@85008|Micromonosporales	201174|Actinobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE,Trans_reg_C
BYD2_k127_4650671_0	105420.BBPO01000027_gene6992	1.662e-315	1002.0	COG1197@1|root,COG1197@2|Bacteria,2GJ42@201174|Actinobacteria,2NGW5@228398|Streptacidiphilus	201174|Actinobacteria	L	TRCF	mfd	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
BYD2_k127_4666014_0	869210.Marky_0743	1.331e-97	341.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	-	-	-	-	-	-	-	-	-	-	CBM_6,Flg_new,LRR_5,PKD
BYD2_k127_4666014_1	225937.HP15_1897	1.766e-24	119.0	COG3291@1|root,COG3828@1|root,COG3291@2|Bacteria,COG3828@2|Bacteria,1QUSE@1224|Proteobacteria	1224|Proteobacteria	G	PFAM FecR protein	-	-	3.2.1.4	ko:K01179,ko:K03933	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	AA10,CBM73,GH5,GH9	-	CBM_2,Calx-beta,Cellulase,PKD
BYD2_k127_4674750_4	1267005.KB911263_gene1322	4.131e-43	165.0	COG0596@1|root,COG0596@2|Bacteria,1RB7R@1224|Proteobacteria,2U5JG@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_4674750_0	469383.Cwoe_1045	1.206e-170	551.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	agpS	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_4674750_3	219305.MCAG_05269	8.992e-46	176.0	COG1846@1|root,COG1846@2|Bacteria,2GJ6W@201174|Actinobacteria,4DEDI@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
BYD2_k127_4674750_2	1463920.JOGB01000026_gene6132	1.919e-71	265.0	COG0697@1|root,COG0697@2|Bacteria,2GMPB@201174|Actinobacteria	201174|Actinobacteria	EG	Permeases of the drug metabolite transporter DMT superfamily	pecM	-	-	ko:K15269	-	-	-	-	ko00000,ko02000	2.A.7.3.3	-	-	EamA
BYD2_k127_4674750_1	1032480.MLP_38980	7.134e-128	421.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the peptidase S8 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
BYD2_k127_4709560_1	1120950.KB892757_gene6566	6.157e-105	346.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,4DNRF@85009|Propionibacteriales	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
BYD2_k127_4709560_6	196162.Noca_2178	4.347e-13	78.0	COG4974@1|root,COG4974@2|Bacteria,2ID5W@201174|Actinobacteria,4DRY6@85009|Propionibacteriales	201174|Actinobacteria	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
BYD2_k127_4709560_0	1214101.BN159_0351	8.911e-110	364.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria	201174|Actinobacteria	H	reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_4709560_3	37919.EP51_10295	1.896e-43	162.0	COG2318@1|root,COG2318@2|Bacteria,2IGJQ@201174|Actinobacteria	201174|Actinobacteria	H	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664
BYD2_k127_4709560_5	1121019.AUMN01000009_gene1868	3.633e-20	98.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
BYD2_k127_4709560_4	1122604.JONR01000034_gene418	5.711e-36	143.0	295V1@1|root,2ZT62@2|Bacteria,1P75A@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4709560_2	1120949.KB903339_gene7989	2.452e-69	244.0	COG0346@1|root,COG0454@1|root,COG0346@2|Bacteria,COG0456@2|Bacteria,2GMTB@201174|Actinobacteria,4DBF4@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_4709560_7	512565.AMIS_3410	0.0009165	42.0	COG4974@1|root,COG4974@2|Bacteria	2|Bacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_4,Phage_integrase
BYD2_k127_4720966_2	713587.THITH_02995	1.772e-05	56.0	COG3227@1|root,COG3291@1|root,COG3227@2|Bacteria,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.18,3.4.11.10	ko:K01186,ko:K05994	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko01002,ko02042	-	GH33	-	PA,PKD,fn3
BYD2_k127_4720966_0	40571.JOEA01000051_gene5882	7.22e-40	160.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DYXD@85010|Pseudonocardiales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
BYD2_k127_4720966_1	1300345.LF41_3131	6.492e-12	76.0	COG3291@1|root,COG4412@1|root,COG3291@2|Bacteria,COG4412@2|Bacteria,1MW5W@1224|Proteobacteria,1S8RX@1236|Gammaproteobacteria,1X53X@135614|Xanthomonadales	135614|Xanthomonadales	E	serine protease	-	-	-	-	-	-	-	-	-	-	-	-	PA
BYD2_k127_480828_10	1122237.AUGQ01000005_gene1376	9.373e-50	185.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4FKGH@85023|Microbacteriaceae	201174|Actinobacteria	E	Belongs to the ABC transporter superfamily	msiK	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
BYD2_k127_480828_3	2074.JNYD01000004_gene4950	1.604e-108	360.0	COG1175@1|root,COG1175@2|Bacteria,2GJGB@201174|Actinobacteria,4DY7F@85010|Pseudonocardiales	201174|Actinobacteria	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
BYD2_k127_480828_4	1121272.KB903249_gene2213	2.395e-105	364.0	COG0395@1|root,COG0395@2|Bacteria,2IDQB@201174|Actinobacteria	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
BYD2_k127_480828_13	222534.KB893717_gene2176	2.818e-20	100.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
BYD2_k127_480828_8	37919.EP51_04915	5.041e-63	220.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4G1T7@85025|Nocardiaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
BYD2_k127_480828_11	1206720.BAFQ01000285_gene6031	2.028e-31	132.0	COG1028@1|root,COG1028@2|Bacteria,2IB3H@201174|Actinobacteria,4FXN3@85025|Nocardiaceae	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_480828_1	246196.MSMEI_0545	6.378e-166	529.0	COG3804@1|root,COG3804@2|Bacteria,2I8CX@201174|Actinobacteria,2330G@1762|Mycobacteriaceae	201174|Actinobacteria	S	dihydrodipicolinate reductase	dapB_1	-	-	-	-	-	-	-	-	-	-	-	DapB_N
BYD2_k127_480828_9	222534.KB893670_gene3858	1.624e-61	219.0	COG1309@1|root,COG1309@2|Bacteria,2I8Z7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_480828_0	365528.KB891137_gene412	5.852e-219	689.0	COG2124@1|root,COG2124@2|Bacteria,2GNZS@201174|Actinobacteria,4EUB3@85013|Frankiales	201174|Actinobacteria	Q	PFAM Cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_480828_2	298654.FraEuI1c_7024	6.872e-112	377.0	COG1028@1|root,COG1028@2|Bacteria,2GIX2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	ko:K07535	ko00362,ko01120,ko01220,map00362,map01120,map01220	M00540	R05582	RC00154	ko00000,ko00001,ko00002,ko01000	-	-	-	adh_short_C2
BYD2_k127_480828_6	1380393.JHVP01000005_gene3634	2.72e-76	276.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4EU4Q@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
BYD2_k127_480828_5	1068978.AMETH_5010	1.604e-96	344.0	COG0784@1|root,COG4928@1|root,COG0784@2|Bacteria,COG4928@2|Bacteria,2IA83@201174|Actinobacteria,4E6QF@85010|Pseudonocardiales	201174|Actinobacteria	T	KAP family P-loop domain	-	-	-	-	-	-	-	-	-	-	-	-	KAP_NTPase,Response_reg
BYD2_k127_480828_7	1229780.BN381_130152	2.304e-66	239.0	2DFS9@1|root,2ZSWU@2|Bacteria	2|Bacteria	S	Virulence factor BrkB	-	-	-	-	-	-	-	-	-	-	-	-	Virul_fac_BrkB
BYD2_k127_480828_12	1386089.N865_04825	3.634e-21	97.0	2EAZS@1|root,32VK9@2|Bacteria,2I73Y@201174|Actinobacteria,4FHIA@85021|Intrasporangiaceae	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
BYD2_k127_480828_14	1896.JOAU01000004_gene104	1.061e-09	64.0	COG0515@1|root,COG0515@2|Bacteria,2IAZC@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
BYD2_k127_480869_1	1229780.BN381_80402	3.678e-43	158.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,3UWA2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphoglycerate kinase	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
BYD2_k127_480869_0	1313172.YM304_21690	5.425e-104	349.0	COG0149@1|root,COG0149@2|Bacteria,2GJXZ@201174|Actinobacteria,4CMZ0@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
BYD2_k127_480869_2	1122602.ATXP01000002_gene678	4.221e-13	74.0	COG4166@1|root,COG4166@2|Bacteria,2GIUH@201174|Actinobacteria,1W7W7@1268|Micrococcaceae	201174|Actinobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	oppA	-	-	ko:K02035,ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
BYD2_k127_4880569_1	187272.Mlg_2099	6.603e-63	219.0	COG0788@1|root,COG0788@2|Bacteria,1MVCF@1224|Proteobacteria,1RN6Q@1236|Gammaproteobacteria,1WXFH@135613|Chromatiales	135613|Chromatiales	F	Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4)	purU	-	3.5.1.10	ko:K01433	ko00630,ko00670,map00630,map00670	-	R00944	RC00026,RC00111	ko00000,ko00001,ko01000	-	-	-	ACT,Formyl_trans_N
BYD2_k127_4880569_4	397278.JOJN01000004_gene1372	1.104e-07	61.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4DR3V@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
BYD2_k127_4880569_2	1313172.YM304_13030	4.821e-26	117.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_4880569_3	591158.SSMG_02436	2.483e-16	91.0	2DWZW@1|root,342QA@2|Bacteria,2GQ7R@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_4880569_0	298654.FraEuI1c_3065	1.679e-118	390.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
BYD2_k127_4897885_12	1313172.YM304_20070	1.176e-46	188.0	COG0683@1|root,COG0683@2|Bacteria,2HFKF@201174|Actinobacteria,4CP0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Receptor family ligand binding region	-	-	-	ko:K01999	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	Peripla_BP_6
BYD2_k127_4897885_8	1229780.BN381_130053	1.584e-85	289.0	COG2872@1|root,COG2872@2|Bacteria,2I8P6@201174|Actinobacteria	201174|Actinobacteria	S	Threonyl alanyl tRNA synthetase SAD	-	-	-	ko:K07050	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA-synt_2c,tRNA_SAD
BYD2_k127_4897885_11	28444.JODQ01000010_gene3087	3.61e-70	246.0	COG1606@1|root,COG1606@2|Bacteria,2GPA1@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ExsB family protein	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	Asn_synthase,NAD_synthase,QueC
BYD2_k127_4897885_5	2002.JOEQ01000008_gene1059	5.207e-134	441.0	COG0446@1|root,COG0446@2|Bacteria,2H7WY@201174|Actinobacteria,4EIFF@85012|Streptosporangiales	201174|Actinobacteria	P	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
BYD2_k127_4897885_3	1313172.YM304_10090	4.581e-156	504.0	COG0004@1|root,COG0004@2|Bacteria,2GIZK@201174|Actinobacteria,4CNTR@84992|Acidimicrobiia	84992|Acidimicrobiia	U	ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
BYD2_k127_4897885_13	1160137.KB907308_gene6842	1.298e-41	172.0	COG0347@1|root,COG0347@2|Bacteria,2IKN1@201174|Actinobacteria,4G17M@85025|Nocardiaceae	201174|Actinobacteria	K	nitrogen regulatory protein P-II	glnB	GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0008144,GO:0008150,GO:0016020,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043531,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K04751	ko02020,map02020	-	-	-	ko00000,ko00001	-	-	-	P-II
BYD2_k127_4897885_2	1313172.YM304_04990	6.329e-182	596.0	COG2844@1|root,COG2844@2|Bacteria,2GMKT@201174|Actinobacteria	201174|Actinobacteria	O	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen	glnD	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008773,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0030312,GO:0044464,GO:0070566,GO:0070569,GO:0071944,GO:0140096	2.7.7.59	ko:K00990	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	-	-	-	ACT,GlnD_UR_UTase,HD,NTP_transf_2
BYD2_k127_4897885_10	1313172.YM304_05030	5.618e-84	285.0	COG1051@1|root,COG1051@2|Bacteria,2HG6C@201174|Actinobacteria,4CN3B@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Hydrolase of X-linked nucleoside diphosphate N terminal	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
BYD2_k127_4897885_15	635013.TherJR_1369	1.843e-27	123.0	COG0463@1|root,COG0463@2|Bacteria,1UJPS@1239|Firmicutes,25F7Y@186801|Clostridia	186801|Clostridia	M	PFAM glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_4897885_4	298655.KI912267_gene7456	8.646e-135	461.0	COG0683@1|root,COG0683@2|Bacteria,2IPWY@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
BYD2_k127_4897885_0	298654.FraEuI1c_1762	2.062e-282	886.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01997,ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_4897885_7	1449069.JMLO01000005_gene1474	7.767e-93	322.0	COG0411@1|root,COG0411@2|Bacteria,2H5WA@201174|Actinobacteria,4FW5R@85025|Nocardiaceae	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	livG	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_4897885_9	298655.KI912267_gene7453	2.855e-84	291.0	COG0410@1|root,COG0410@2|Bacteria,2I8GT@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_4897885_17	298655.KI912267_gene7452	1.253e-19	99.0	2DQKP@1|root,337GR@2|Bacteria,2GU0C@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4897885_1	1240349.ANGC01000013_gene531	3.769e-236	741.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4FTYX@85025|Nocardiaceae	201174|Actinobacteria	IQ	Acyl-CoA synthetase	fadD8	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0051087	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_4897885_14	1229780.BN381_10161	1.444e-27	119.0	COG2026@1|root,COG2026@2|Bacteria,2IRES@201174|Actinobacteria	201174|Actinobacteria	DJ	ParE toxin of type II toxin-antitoxin system, parDE	-	-	-	ko:K06218	-	-	-	-	ko00000,ko02048	-	-	-	ParE_toxin
BYD2_k127_4897885_16	1229780.BN381_10160	5.79e-25	119.0	COG2161@1|root,COG2161@2|Bacteria,2IRS2@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
BYD2_k127_4897885_6	1278078.G419_10537	1.845e-103	347.0	COG1574@1|root,COG1574@2|Bacteria,2GKXR@201174|Actinobacteria,4FVZZ@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
BYD2_k127_492797_0	656024.FsymDg_1995	4.734e-99	326.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4ETUQ@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
BYD2_k127_492797_6	1089544.KB912942_gene6645	2.079e-10	64.0	COG3609@1|root,COG3609@2|Bacteria,2GS33@201174|Actinobacteria,4E7DS@85010|Pseudonocardiales	201174|Actinobacteria	K	addiction module antidote protein, CC2985 family	-	GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0097351	-	-	-	-	-	-	-	-	-	-	RHH_1
BYD2_k127_492797_4	1121924.ATWH01000005_gene2690	6.451e-46	172.0	COG2337@1|root,COG2337@2|Bacteria,2IM6R@201174|Actinobacteria,4FSU9@85023|Microbacteriaceae	201174|Actinobacteria	T	PemK-like, MazF-like toxin of type II toxin-antitoxin system	-	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045926,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
BYD2_k127_492797_3	1229780.BN381_310086	1.336e-48	191.0	COG1807@1|root,COG1807@2|Bacteria,2H9UZ@201174|Actinobacteria	201174|Actinobacteria	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_492797_1	365528.KB891213_gene2459	7.85e-79	295.0	COG1807@1|root,COG1807@2|Bacteria,2IITJ@201174|Actinobacteria	201174|Actinobacteria	M	Evidence 5 No homology to any previously reported sequences	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
BYD2_k127_492797_2	1136417.AZWE01000049_gene4743	1.454e-55	222.0	COG1835@1|root,COG1835@2|Bacteria,2GP6W@201174|Actinobacteria,4DM2A@85008|Micromonosporales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BYD2_k127_492797_5	1229780.BN381_310090	3.859e-41	170.0	COG1807@1|root,COG1835@1|root,COG1807@2|Bacteria,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	aftB	GO:0008150,GO:0040007	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	Acyl_transf_3,PMT_2
BYD2_k127_4953006_0	436229.JOEH01000010_gene5333	8.806e-186	611.0	COG0305@1|root,COG1372@1|root,COG0305@2|Bacteria,COG1372@2|Bacteria,2GKXQ@201174|Actinobacteria,2NEZI@228398|Streptacidiphilus	201174|Actinobacteria	L	DnaB-like helicase N terminal domain	dnaB	GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0030312,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C,Intein_splicing,LAGLIDADG_3
BYD2_k127_4966404_5	408672.NBCG_00680	4.296e-112	370.0	COG4188@1|root,COG4188@2|Bacteria,2H3T8@201174|Actinobacteria	201174|Actinobacteria	S	dienelactone hydrolase	-	-	3.1.1.101	ko:K21104	-	-	R11540	-	ko00000,ko01000	-	-	-	Abhydrolase_5,Chlorophyllase2,DLH,Hydrolase_4,PAF-AH_p_II
BYD2_k127_4966404_1	1123024.AUII01000014_gene4289	7.361e-221	695.0	COG1690@1|root,COG1690@2|Bacteria,2GIUP@201174|Actinobacteria,4E0T7@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the RtcB family	rtcB	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944	6.5.1.3	ko:K14415	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	RtcB
BYD2_k127_4966404_11	1306406.ASHX01000001_gene1880	3.919e-27	116.0	COG1371@1|root,COG1371@2|Bacteria,2IS0V@201174|Actinobacteria	201174|Actinobacteria	S	Archease protein family (MTH1598/TM1083)	-	-	-	-	-	-	-	-	-	-	-	-	Archease
BYD2_k127_4966404_2	298653.Franean1_3766	8.804e-179	570.0	COG1073@1|root,COG1926@1|root,COG1073@2|Bacteria,COG1926@2|Bacteria,2GJUU@201174|Actinobacteria,4ES6H@85013|Frankiales	201174|Actinobacteria	S	Phosphoribosyl transferase domain	-	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K07100	-	-	-	-	ko00000	-	-	-	DLH,Pribosyltran
BYD2_k127_4966404_4	1123322.KB904699_gene4621	3.178e-129	441.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria	201174|Actinobacteria	M	Capsule synthesis protein	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
BYD2_k127_4966404_7	1240349.ANGC01000066_gene88	4.298e-78	263.0	COG1839@1|root,COG1839@2|Bacteria,2IAR3@201174|Actinobacteria,4FYWC@85025|Nocardiaceae	201174|Actinobacteria	S	Adenosine specific kinase	-	-	-	ko:K09129	-	-	-	-	ko00000	-	-	-	Adenosine_kin
BYD2_k127_4966404_0	1229780.BN381_90023	0.0	1446.0	COG0553@1|root,COG0553@2|Bacteria,2GISC@201174|Actinobacteria,3UX1U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3670,Helicase_C,SNF2_N
BYD2_k127_4966404_6	1229780.BN381_130179	1.32e-82	286.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_4966404_8	457429.ABJI02000073_gene5168	5.377e-65	236.0	COG3315@1|root,COG3315@2|Bacteria,2GJIS@201174|Actinobacteria	201174|Actinobacteria	Q	Evidence 4 Homologs of previously reported genes of	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_4966404_3	35754.JNYJ01000012_gene939	3.563e-159	511.0	2DBF7@1|root,2Z8X0@2|Bacteria,2I0F0@201174|Actinobacteria,4DBGG@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
BYD2_k127_4966404_10	1463903.JOIZ01000003_gene1627	2.017e-53	195.0	COG3945@1|root,COG3945@2|Bacteria	2|Bacteria	P	hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
BYD2_k127_4966404_9	215803.DB30_3631	8.367e-59	218.0	COG2364@1|root,COG2364@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4966404_15	1463825.JNXC01000007_gene796	9.766e-13	79.0	COG1742@1|root,COG1742@2|Bacteria,2IKM8@201174|Actinobacteria,4E4I4@85010|Pseudonocardiales	201174|Actinobacteria	S	UPF0060 membrane protein	-	GO:0005575,GO:0005576	-	ko:K09771	-	-	-	-	ko00000,ko02000	2.A.7.26	-	-	UPF0060
BYD2_k127_4966404_12	1075090.GOAMR_54_00250	1.328e-24	111.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
BYD2_k127_4966404_13	446466.Cfla_0420	6.42e-19	91.0	COG0789@1|root,COG0789@2|Bacteria,2INKP@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR-DNA-bind,MerR_1
BYD2_k127_4987881_11	1123023.JIAI01000004_gene8092	1.154e-32	138.0	COG1716@1|root,COG1716@2|Bacteria,2GK5I@201174|Actinobacteria,4E5TU@85010|Pseudonocardiales	201174|Actinobacteria	T	Forkhead associated domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR,FHA,zinc_ribbon_2
BYD2_k127_4987881_5	1463854.JOHT01000016_gene7003	1.998e-130	434.0	COG2304@1|root,COG2304@2|Bacteria,2GMWM@201174|Actinobacteria	201174|Actinobacteria	T	von willebrand factor type a	-	-	-	-	-	-	-	-	-	-	-	-	VWA_2,VWA_3
BYD2_k127_4987881_10	561175.KB894094_gene1822	2.67e-42	175.0	COG0631@1|root,COG0631@2|Bacteria,2GKDM@201174|Actinobacteria,4ENSI@85012|Streptosporangiales	201174|Actinobacteria	T	Serine/threonine phosphatases, family 2C, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	DZR,PP2C_2
BYD2_k127_4987881_2	512565.AMIS_53290	3.185e-149	516.0	COG0515@1|root,COG4783@1|root,COG0515@2|Bacteria,COG4783@2|Bacteria,2GJ24@201174|Actinobacteria,4DBUT@85008|Micromonosporales	201174|Actinobacteria	KLT	Protein kinase G rubredoxin domain	pknG	GO:0001898,GO:0001899,GO:0002682,GO:0002684,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006464,GO:0006468,GO:0006520,GO:0006536,GO:0006538,GO:0006541,GO:0006543,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009405,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0019752,GO:0030100,GO:0031341,GO:0031342,GO:0031347,GO:0031349,GO:0032879,GO:0035821,GO:0036211,GO:0040007,GO:0042268,GO:0042802,GO:0043170,GO:0043207,GO:0043412,GO:0043436,GO:0043648,GO:0043649,GO:0043900,GO:0043901,GO:0043903,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044403,GO:0044413,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0045918,GO:0046395,GO:0046777,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048584,GO:0050764,GO:0050776,GO:0050778,GO:0050789,GO:0050794,GO:0050896,GO:0051049,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0051709,GO:0051710,GO:0051711,GO:0051713,GO:0051802,GO:0051803,GO:0051817,GO:0051832,GO:0052027,GO:0052031,GO:0052164,GO:0052173,GO:0052190,GO:0052200,GO:0052231,GO:0052250,GO:0052255,GO:0052303,GO:0052348,GO:0052369,GO:0052509,GO:0052510,GO:0052550,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052567,GO:0052572,GO:0060627,GO:0065007,GO:0071704,GO:0071944,GO:0075136,GO:0080134,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	2.7.11.1	ko:K14949	ko05152,map05152	-	-	-	ko00000,ko00001,ko01000,ko01001	-	-	-	Pkinase,PknG_TPR,PknG_rubred
BYD2_k127_4987881_14	570268.ANBB01000045_gene1112	1.688e-07	65.0	2EBHT@1|root,335I8@2|Bacteria,2GMT9@201174|Actinobacteria,4EJQN@85012|Streptosporangiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4987881_9	1114959.SZMC14600_01152	4.2e-65	250.0	COG0834@1|root,COG0834@2|Bacteria,2GJH8@201174|Actinobacteria,4DYY6@85010|Pseudonocardiales	201174|Actinobacteria	ET	Periplasmic component of amino acid ABC-type transporter signal transduction system	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
BYD2_k127_4987881_12	593907.Celgi_1523	1.612e-28	132.0	COG5278@1|root,COG5278@2|Bacteria,2GJ1Q@201174|Actinobacteria,4F1BR@85016|Cellulomonadaceae	201174|Actinobacteria	T	phosphoserine phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_4987881_7	479435.Kfla_5999	1.552e-107	367.0	COG2843@1|root,COG2843@2|Bacteria,2GK15@201174|Actinobacteria,4DQRB@85009|Propionibacteriales	201174|Actinobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
BYD2_k127_4987881_15	1137269.AZWL01000001_gene5573	2.086e-07	63.0	COG3568@1|root,COG3568@2|Bacteria,2IGGC@201174|Actinobacteria	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_4987881_4	469383.Cwoe_0463	3.19e-133	433.0	COG2267@1|root,COG2267@2|Bacteria,2I3AI@201174|Actinobacteria,4CQYX@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_4987881_1	1048339.KB913029_gene661	4.211e-167	540.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ETYU@85013|Frankiales	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K00666,ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BYD2_k127_4987881_3	1229780.BN381_10328	1.156e-145	482.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,3UX6E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
BYD2_k127_4987881_0	526225.Gobs_1069	1.268e-180	596.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria,4ES6Q@85013|Frankiales	201174|Actinobacteria	GT	PEP-utilising enzyme, mobile domain	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
BYD2_k127_4987881_8	1380347.JNII01000006_gene1305	6.01e-107	352.0	COG5588@1|root,COG5588@2|Bacteria,2HIPH@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
BYD2_k127_4987881_6	526225.Gobs_0843	5.871e-120	397.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria	201174|Actinobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
BYD2_k127_4999796_4	469383.Cwoe_2222	1.863e-106	354.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria,4CPXP@84995|Rubrobacteria	84995|Rubrobacteria	K	RNA polymerase, sigma-24 subunit, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_4999796_3	526225.Gobs_2584	1.284e-118	391.0	COG0451@1|root,COG0451@2|Bacteria,2I2SW@201174|Actinobacteria,4ETNA@85013|Frankiales	201174|Actinobacteria	GM	PFAM NAD-dependent epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
BYD2_k127_4999796_5	926564.KI911765_gene4614	8.093e-71	252.0	COG3576@1|root,COG3576@2|Bacteria,2I3NE@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_4999796_0	1283300.ATXB01000001_gene1711	7.819e-304	981.0	COG1554@1|root,COG1554@2|Bacteria,1MWJE@1224|Proteobacteria,1RPN6@1236|Gammaproteobacteria	1236|Gammaproteobacteria	G	hydrolase family 65, central catalytic	ycjT	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0016787,GO:0030312,GO:0044464,GO:0071944	2.4.1.64,3.2.1.28,5.4.2.6	ko:K01194,ko:K01838,ko:K04844,ko:K05342	ko00500,ko01100,map00500,map01100	-	R00010,R02727,R02728,R11310	RC00049,RC00408	ko00000,ko00001,ko00537,ko01000	-	GH37,GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
BYD2_k127_4999796_1	234267.Acid_3078	8.698e-233	733.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_4999796_2	234267.Acid_3077	1.382e-218	722.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria	57723|Acidobacteria	Q	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
BYD2_k127_5019993_3	1386089.N865_16650	2.416e-40	164.0	2ANPZ@1|root,31DPH@2|Bacteria,2INCA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5019993_1	525909.Afer_1269	2.605e-100	348.0	COG1253@1|root,COG1253@2|Bacteria,2GIWR@201174|Actinobacteria,4CP58@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Transporter associated domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS,CorC_HlyC,DUF21
BYD2_k127_5019993_4	1313172.YM304_23950	4.76e-34	153.0	COG0319@1|root,COG0319@2|Bacteria,2GMUF@201174|Actinobacteria,4CN8G@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	-	ko:K07042	-	-	-	-	ko00000,ko03009	-	-	-	UPF0054
BYD2_k127_5019993_0	1229780.BN381_330095	6.737e-136	439.0	COG1702@1|root,COG1702@2|Bacteria,2GK0W@201174|Actinobacteria,3UWEM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	PhoH-like protein	phoH	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
BYD2_k127_5019993_2	1068978.AMETH_1661	6.939e-83	288.0	COG2843@1|root,COG2843@2|Bacteria,2GP72@201174|Actinobacteria,4E1BJ@85010|Pseudonocardiales	201174|Actinobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M15_4
BYD2_k127_5055079_1	671143.DAMO_1031	9.26e-78	274.0	COG0155@1|root,COG0155@2|Bacteria,2NPHB@2323|unclassified Bacteria	2|Bacteria	P	Nitrite and sulphite reductase 4Fe-4S domain	cysI	-	1.7.1.15,1.7.7.1,1.8.1.2,1.8.7.1	ko:K00362,ko:K00366,ko:K00381,ko:K00392	ko00910,ko00920,ko01100,ko01120,map00910,map00920,map01100,map01120	M00176,M00530,M00531	R00787,R00790,R00858,R00859,R03600	RC00065,RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	HEPN,NIR_SIR,NIR_SIR_ferr
BYD2_k127_5055079_4	1341646.CBMO010000142_gene2468	6.488e-55	214.0	COG0175@1|root,COG0175@2|Bacteria,2GJ3Z@201174|Actinobacteria,2345B@1762|Mycobacteriaceae	201174|Actinobacteria	EH	Belongs to the PAPS reductase family. CysH subfamily	cysH	GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004604,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016667,GO:0016671,GO:0019344,GO:0019752,GO:0040007,GO:0043436,GO:0043866,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.8.4.10,1.8.4.8	ko:K00390	ko00920,ko01100,ko01120,map00920,map01100,map01120	M00176	R02021	RC00007,RC02862	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2392	PAPS_reduct
BYD2_k127_5055079_2	1394178.AWOO02000026_gene5105	3.527e-73	277.0	COG0477@1|root,COG0477@2|Bacteria,2I607@201174|Actinobacteria	201174|Actinobacteria	EGP	Transmembrane secretion effector	-	-	2.7.4.9	ko:K00943	ko00240,ko01100,map00240,map01100	M00053	R02094,R02098	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	MFS_1,MFS_3
BYD2_k127_5055079_6	1122182.KB903834_gene6024	1.51e-13	82.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,4DD5U@85008|Micromonosporales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
BYD2_k127_5055079_5	1906.SFRA_02045	5.312e-24	117.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria	201174|Actinobacteria	S	DegV family	-	-	-	-	-	-	-	-	-	-	-	-	DegV
BYD2_k127_5055079_7	309801.trd_A0581	2.377e-13	81.0	COG0344@1|root,COG0344@2|Bacteria,2GBUF@200795|Chloroflexi,27ZAT@189775|Thermomicrobia	189775|Thermomicrobia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
BYD2_k127_5055079_3	1896.JOAU01000043_gene2735	1.325e-57	213.0	COG3327@1|root,COG3327@2|Bacteria	2|Bacteria	K	negative regulation of DNA-templated transcription, initiation	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
BYD2_k127_5055079_0	1117379.BABA_14322	3.585e-178	582.0	COG2141@1|root,COG2141@2|Bacteria,1TRBN@1239|Firmicutes,4HBYT@91061|Bacilli,1ZHB1@1386|Bacillus	91061|Bacilli	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_50695_2	1122182.KB903816_gene1736	5.989e-39	162.0	COG1733@1|root,COG1733@2|Bacteria,2IM83@201174|Actinobacteria,4DEX9@85008|Micromonosporales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
BYD2_k127_50695_1	1254432.SCE1572_23970	1.309e-99	331.0	COG1028@1|root,COG1028@2|Bacteria,1MUAY@1224|Proteobacteria,42NIM@68525|delta/epsilon subdivisions	1224|Proteobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_50695_0	68170.KL590520_gene7927	1.492e-107	353.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4E388@85010|Pseudonocardiales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
BYD2_k127_5099267_3	1313172.YM304_00280	1.003e-113	377.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_5099267_1	1089544.KB912942_gene1155	5.053e-166	529.0	COG1793@1|root,COG1793@2|Bacteria,2I2EA@201174|Actinobacteria,4DX83@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA ligase	ligC	-	-	-	-	-	-	-	-	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M
BYD2_k127_5099267_6	365528.KB891230_gene1937	5.464e-68	241.0	COG1376@1|root,COG1376@2|Bacteria,2INDP@201174|Actinobacteria	201174|Actinobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
BYD2_k127_5099267_0	1313172.YM304_37200	3.766e-258	806.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMPB@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	2.1.3.15,6.4.1.3	ko:K01966	ko00280,ko00630,ko00640,ko01100,ko01120,ko01130,ko01200,map00280,map00630,map00640,map01100,map01120,map01130,map01200	M00373,M00741	R01859	RC00097,RC00609	ko00000,ko00001,ko00002,ko01000	-	-	-	Carboxyl_trans
BYD2_k127_5099267_4	1313172.YM304_37240	3.976e-100	336.0	COG1409@1|root,COG1409@2|Bacteria,2IDNH@201174|Actinobacteria	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	3.1.4.53	ko:K03651	ko00230,ko02025,map00230,map02025	-	R00191	RC00296	ko00000,ko00001,ko01000	-	-	-	Metallophos,Pur_ac_phosph_N
BYD2_k127_5099267_5	477641.MODMU_4708	3.591e-85	305.0	COG1807@1|root,COG1807@2|Bacteria,2GNPY@201174|Actinobacteria	201174|Actinobacteria	M	capsule polysaccharide biosynthetic process	-	-	-	ko:K13687	-	-	-	-	ko00000,ko01000,ko01003	-	GT89	-	-
BYD2_k127_5099267_7	35754.JNYJ01000014_gene4862	1.012e-43	176.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria,4D9CD@85008|Micromonosporales	201174|Actinobacteria	I	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BYD2_k127_5099267_2	1313172.YM304_02580	6.152e-134	443.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria	201174|Actinobacteria	C	L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
BYD2_k127_5177285_2	1289387.AUKW01000018_gene2194	2.614e-102	342.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	LZ_Tnp_IS481,rve
BYD2_k127_5177285_5	345341.KUTG_08729	3.596e-46	175.0	2B10M@1|root,31TDX@2|Bacteria,2GS84@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5177285_1	477641.MODMU_1857	9.518e-138	446.0	COG0451@1|root,COG0451@2|Bacteria,2GNT1@201174|Actinobacteria,4ESJ9@85013|Frankiales	201174|Actinobacteria	GM	epimerase dehydratase	galE4	-	-	-	-	-	-	-	-	-	-	-	Epimerase
BYD2_k127_5177285_3	351607.Acel_0516	4.755e-99	335.0	COG2203@1|root,COG4585@1|root,COG2203@2|Bacteria,COG4585@2|Bacteria,2I312@201174|Actinobacteria,4EXC4@85013|Frankiales	201174|Actinobacteria	T	histidine kinase, dimerisation and phosphoacceptor region	devS	GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564	2.7.13.3	ko:K07682	ko02020,map02020	M00482	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	GAF,GAF_2,GAF_3,HATPase_c,HATPase_c_2,HisKA_3
BYD2_k127_5177285_6	1121877.JQKF01000002_gene1717	2.632e-05	53.0	2BM3X@1|root,32FM8@2|Bacteria,2HH03@201174|Actinobacteria,4CP0F@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5177285_4	298654.FraEuI1c_0966	1.693e-71	258.0	COG3281@1|root,COG3281@2|Bacteria,2GKAP@201174|Actinobacteria,4ERHN@85013|Frankiales	201174|Actinobacteria	G	protein, probably involved in trehalose biosynthesis	treX	-	2.7.1.175	ko:K16146	ko00500,ko01100,map00500,map01100	-	R09945	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	APH
BYD2_k127_5177285_0	1463825.JNXC01000003_gene3614	2.176e-195	634.0	COG0296@1|root,COG0296@2|Bacteria,2GJ5C@201174|Actinobacteria,4E0S6@85010|Pseudonocardiales	201174|Actinobacteria	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
BYD2_k127_518813_0	1313172.YM304_19210	2.742e-175	559.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,4CMTY@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
BYD2_k127_518813_1	1298863.AUEP01000002_gene1491	9.323e-142	460.0	COG0205@1|root,COG0205@2|Bacteria,2GK6W@201174|Actinobacteria,4DPJ3@85009|Propionibacteriales	201174|Actinobacteria	G	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
BYD2_k127_5189390_0	1229780.BN381_100146	1.007e-108	382.0	COG0744@1|root,COG0744@2|Bacteria,2GK21@201174|Actinobacteria	201174|Actinobacteria	M	penicillin-binding protein	ponA	GO:0001666,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0008144,GO:0008150,GO:0008658,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0033218,GO:0033293,GO:0033554,GO:0036094,GO:0036293,GO:0036294,GO:0042221,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0050896,GO:0051716,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0097159,GO:1901363,GO:1901681	-	-	-	-	-	-	-	-	-	-	Transgly,Transpeptidase
BYD2_k127_5189390_1	1229780.BN381_100144	2.938e-105	349.0	COG0413@1|root,COG0413@2|Bacteria,2GJP6@201174|Actinobacteria,3UW6F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate	panB	GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0040007,GO:0042364,GO:0042398,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072330,GO:1901564,GO:1901566,GO:1901576	2.1.2.11	ko:K00606	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R01226	RC00022,RC00200	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_transf
BYD2_k127_5189390_6	1313172.YM304_42660	5.984e-26	120.0	COG1430@1|root,COG1430@2|Bacteria,2GX4D@201174|Actinobacteria	201174|Actinobacteria	S	Uncharacterized ACR, COG1430	-	-	-	ko:K09005	-	-	-	-	ko00000	-	-	-	DUF192
BYD2_k127_5189390_5	1229780.BN381_100143	1.004e-28	118.0	COG0360@1|root,COG0360@2|Bacteria,2IQHD@201174|Actinobacteria,3UWQU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds together with S18 to 16S ribosomal RNA	rpsF	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015935,GO:0016020,GO:0019843,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071944,GO:0097159,GO:1901363,GO:1990904	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
BYD2_k127_5189390_2	1229780.BN381_100142	1.045e-53	192.0	COG0629@1|root,COG0629@2|Bacteria,2GMM3@201174|Actinobacteria,3UWQD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Single-strand binding protein family	ssb	GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0042221,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071944,GO:0097159,GO:1901363	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
BYD2_k127_5189390_4	1229780.BN381_100141	3.4e-31	138.0	COG0238@1|root,COG0238@2|Bacteria,2IQ92@201174|Actinobacteria,3UWV6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
BYD2_k127_5189390_3	1313172.YM304_42610	1.205e-42	160.0	COG0359@1|root,COG0359@2|Bacteria,2IKX7@201174|Actinobacteria,4CNBU@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
BYD2_k127_5197586_5	469383.Cwoe_1897	7.847e-09	58.0	COG2010@1|root,COG3794@1|root,COG2010@2|Bacteria,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	pbrT	-	-	ko:K07243	-	-	-	-	ko00000,ko02000	2.A.108.1,2.A.108.2	-	-	Cytochrom_C,Cytochrome_CBB3,FTR1
BYD2_k127_5197586_9	665577.JH993791_gene187	0.0001251	55.0	2FDIJ@1|root,345K0@2|Bacteria,2GPVJ@201174|Actinobacteria	201174|Actinobacteria	S	Neocarzinostatin family	-	-	-	-	-	-	-	-	-	-	-	-	Neocarzinostat
BYD2_k127_5197586_8	566461.SSFG_07665	0.0001251	55.0	2FDIJ@1|root,345K0@2|Bacteria,2GPVJ@201174|Actinobacteria	201174|Actinobacteria	S	Neocarzinostatin family	-	-	-	-	-	-	-	-	-	-	-	-	Neocarzinostat
BYD2_k127_5197586_4	1121957.ATVL01000006_gene2744	3.807e-13	83.0	COG2272@1|root,COG2272@2|Bacteria,4PMEB@976|Bacteroidetes,47Y2U@768503|Cytophagia	976|Bacteroidetes	I	Carboxylesterase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,COesterase
BYD2_k127_5197586_3	1127134.NOCYR_2782	1.956e-17	95.0	2C56P@1|root,2ZJ2W@2|Bacteria,2IKDI@201174|Actinobacteria,4G0AJ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5197586_1	266940.Krad_0501	1.355e-26	113.0	COG0640@1|root,COG0640@2|Bacteria,2IQDH@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
BYD2_k127_5197586_6	1137269.AZWL01000042_gene1241	6.225e-07	61.0	COG1595@1|root,COG1595@2|Bacteria,2GPID@201174|Actinobacteria	201174|Actinobacteria	K	DNA-templated transcription, initiation	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5197586_0	1380354.JIAN01000009_gene3760	1.076e-49	205.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria	201174|Actinobacteria	NU	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,LysM
BYD2_k127_5197586_2	219305.MCAG_05003	5.109e-25	105.0	COG0346@1|root,COG0789@1|root,COG0346@2|Bacteria,COG0789@2|Bacteria	2|Bacteria	K	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,MerR_1
BYD2_k127_5197586_7	488538.SAR116_1275	5.85e-05	47.0	COG0317@1|root,COG0317@2|Bacteria,1N2BZ@1224|Proteobacteria,2VGHX@28211|Alphaproteobacteria,4BS7D@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
BYD2_k127_5210303_0	237609.PSAKL28_30820	1.547e-222	696.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,1RMBQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	C	belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3,1.2.1.8	ko:K00128,ko:K00130	ko00010,ko00053,ko00071,ko00260,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00260,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135,M00555	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02565,R02566,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_5210303_1	479432.Sros_7928	5.384e-130	441.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4EH0T@85012|Streptosporangiales	201174|Actinobacteria	I	Coenzyme A transferase	gctA	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
BYD2_k127_5210303_3	1380393.JHVP01000004_gene680	7.208e-88	291.0	COG3631@1|root,COG3631@2|Bacteria,2II8E@201174|Actinobacteria,4EVCD@85013|Frankiales	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_5210303_2	1464048.JNZS01000007_gene4480	4.185e-94	323.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DB71@85008|Micromonosporales	201174|Actinobacteria	I	Coenzyme A transferase	catJ	-	2.8.3.12	ko:K01040	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
BYD2_k127_5210303_4	1120949.KB903298_gene5692	1.992e-07	60.0	COG1454@1|root,COG1454@2|Bacteria,2I2FD@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.3.1.32	ko:K00217	ko00361,ko00362,ko00364,ko00623,ko01100,ko01120,ko01220,map00361,map00362,map00364,map00623,map01100,map01120,map01220	-	R02988,R02989,R05355,R06848,R07781,R09137,R09138,R09223,R09224	RC00107,RC01335,RC01689,RC02442	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
BYD2_k127_5225081_0	1122611.KB903945_gene1320	7.225e-164	522.0	COG0402@1|root,COG0402@2|Bacteria,2GKKM@201174|Actinobacteria,4EI4H@85012|Streptosporangiales	201174|Actinobacteria	F	Amidohydrolase family	-	-	3.5.4.1	ko:K01485	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922	RC00074,RC00514,RC00809	ko00000,ko00001,ko01000	-	-	-	Amidohydro_3
BYD2_k127_5230463_3	1504981.KO116_2345	1.481e-16	79.0	COG0604@1|root,COG0604@2|Bacteria,1MV3W@1224|Proteobacteria,1RMHG@1236|Gammaproteobacteria,1XHDE@135619|Oceanospirillales	135619|Oceanospirillales	C	alcohol dehydrogenase	-	-	-	ko:K19745	ko00640,ko01100,map00640,map01100	-	R00919	RC00095	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_5230463_0	1206731.BAGB01000047_gene5454	1.537e-131	450.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria,4FXMK@85025|Nocardiaceae	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_5230463_1	1283283.ATXA01000001_gene384	1.426e-101	349.0	COG1960@1|root,COG1960@2|Bacteria,2I8VD@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_5230463_2	298654.FraEuI1c_2832	7.137e-28	117.0	COG0318@1|root,COG0318@2|Bacteria,2GK1Y@201174|Actinobacteria,4EU2C@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_523650_4	326424.FRAAL6309	4.537e-99	331.0	COG0604@1|root,COG0604@2|Bacteria,2GKHW@201174|Actinobacteria,4EUQB@85013|Frankiales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_523650_0	1229780.BN381_10094	2.502e-197	625.0	COG0064@1|root,COG0064@2|Bacteria,2GJJH@201174|Actinobacteria,3UW72@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
BYD2_k127_523650_5	235985.BBPN01000033_gene2	5.229e-72	260.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria,2NF96@228398|Streptacidiphilus	201174|Actinobacteria	S	Sterol carrier protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
BYD2_k127_523650_8	1048339.KB913029_gene2864	2.415e-21	96.0	COG1977@1|root,COG1977@2|Bacteria,2GQM9@201174|Actinobacteria,4EWS6@85013|Frankiales	201174|Actinobacteria	H	ThiS family	-	-	-	ko:K03636	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
BYD2_k127_523650_1	1120950.KB892707_gene4819	2.332e-152	503.0	COG4447@1|root,COG4447@2|Bacteria,2GM8J@201174|Actinobacteria,4DN0W@85009|Propionibacteriales	201174|Actinobacteria	S	cellulose binding	-	-	-	-	-	-	-	-	-	-	-	-	BNR_6
BYD2_k127_523650_6	1304865.JAGF01000001_gene983	1.125e-42	172.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria	201174|Actinobacteria	J	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
BYD2_k127_523650_7	1304865.JAGF01000001_gene984	4.088e-25	115.0	292NE@1|root,2ZQ69@2|Bacteria,2I8AI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_523650_3	1906.SFRA_12710	5.645e-115	391.0	COG0534@1|root,COG0534@2|Bacteria,2GJE3@201174|Actinobacteria	201174|Actinobacteria	V	MATE efflux family protein	dinF	-	-	-	-	-	-	-	-	-	-	-	MatE
BYD2_k127_523650_2	1313172.YM304_33670	2.051e-121	425.0	COG0129@1|root,COG0129@2|Bacteria,2GJIJ@201174|Actinobacteria,4CMQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Dehydratase family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
BYD2_k127_5271486_0	1229780.BN381_90066	4.454e-86	291.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria,3UWE1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
BYD2_k127_5278751_10	1287475.HMPREF1650_03160	2.337e-10	62.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,22KFQ@1653|Corynebacteriaceae	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	ko:K03556,ko:K06886	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
BYD2_k127_5278751_9	469383.Cwoe_1049	9.01e-11	75.0	COG0346@1|root,COG0346@2|Bacteria,2IIM8@201174|Actinobacteria,4CQQJ@84995|Rubrobacteria	84995|Rubrobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
BYD2_k127_5278751_2	298655.KI912266_gene3868	5.937e-139	452.0	COG4638@1|root,COG4638@2|Bacteria	2|Bacteria	P	Rieske (2fe-2S)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske
BYD2_k127_5278751_7	298655.KI912266_gene5044	5.166e-58	211.0	COG1309@1|root,COG1309@2|Bacteria,2IDYQ@201174|Actinobacteria	201174|Actinobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
BYD2_k127_5278751_3	222534.KB893716_gene1878	1.886e-120	412.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_5278751_4	298655.KI912266_gene3865	5.381e-97	328.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_5278751_1	298655.KI912266_gene3866	8.029e-148	481.0	COG2159@1|root,COG2159@2|Bacteria,2HG7W@201174|Actinobacteria,4EX8Y@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_5278751_5	356851.JOAN01000011_gene5426	2.551e-82	292.0	COG1609@1|root,COG1609@2|Bacteria,2GJV7@201174|Actinobacteria,4DBWN@85008|Micromonosporales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
BYD2_k127_5278751_0	1068978.AMETH_2735	1.074e-148	478.0	COG0389@1|root,COG0389@2|Bacteria,2GKHC@201174|Actinobacteria,4DZPZ@85010|Pseudonocardiales	201174|Actinobacteria	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	HHH_5,IMS,IMS_C,IMS_HHH
BYD2_k127_5278751_6	460265.Mnod_0870	3.269e-79	290.0	COG1835@1|root,COG1835@2|Bacteria,1MV2W@1224|Proteobacteria,2TRT8@28211|Alphaproteobacteria,1JTVR@119045|Methylobacteriaceae	28211|Alphaproteobacteria	I	PFAM Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BYD2_k127_5279329_1	749927.AMED_5168	9.287e-118	414.0	COG0443@1|root,COG0443@2|Bacteria,2GNTE@201174|Actinobacteria,4E043@85010|Pseudonocardiales	201174|Actinobacteria	O	Hsp70 protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
BYD2_k127_5279329_15	263358.VAB18032_22430	3.231e-10	74.0	COG5401@1|root,COG5401@2|Bacteria,2IRGJ@201174|Actinobacteria,4DF2T@85008|Micromonosporales	201174|Actinobacteria	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
BYD2_k127_5279329_3	1313172.YM304_19250	3.469e-113	391.0	COG0642@1|root,COG2205@2|Bacteria,2GK1J@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_5279329_2	1313172.YM304_19260	8.998e-114	370.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_5279329_7	390989.JOEG01000002_gene4349	1.065e-68	258.0	COG0483@1|root,COG0483@2|Bacteria,2GJQE@201174|Actinobacteria,4DACR@85008|Micromonosporales	201174|Actinobacteria	G	Inositol monophosphatase	suhB	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
BYD2_k127_5279329_5	1121877.JQKF01000004_gene1090	1.08e-85	297.0	COG2008@1|root,COG2008@2|Bacteria,2GMNV@201174|Actinobacteria,4CNM1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Beta-eliminating lyase	-	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
BYD2_k127_5279329_10	1121877.JQKF01000004_gene1089	3.567e-46	188.0	COG2120@1|root,COG2120@2|Bacteria,2HF8J@201174|Actinobacteria,4CNQ6@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
BYD2_k127_5279329_11	1313172.YM304_14780	1.524e-41	162.0	COG2606@1|root,COG2606@2|Bacteria,2HH14@201174|Actinobacteria,4CP1D@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Aminoacyl-tRNA editing domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
BYD2_k127_5279329_9	1229780.BN381_140026	1.34e-46	179.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	MA20_41050	-	3.6.1.67	ko:K08310	ko00790,map00790	M00126	R04638	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NUDIX
BYD2_k127_5279329_0	1313172.YM304_19290	1.798e-125	415.0	COG0389@1|root,COG0389@2|Bacteria,2GKBI@201174|Actinobacteria,4CNR5@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	-	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
BYD2_k127_5279329_13	525909.Afer_0682	6.374e-23	104.0	2ERJT@1|root,33J59@2|Bacteria,2HGGQ@201174|Actinobacteria,4CNDW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Protein of unknown function (DUF3040)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3040
BYD2_k127_5279329_8	1313172.YM304_19310	1.91e-68	264.0	COG1305@1|root,COG1305@2|Bacteria,2HH1I@201174|Actinobacteria,4CP1R@84992|Acidimicrobiia	2|Bacteria	E	Transglutaminase/protease-like homologues	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
BYD2_k127_5279329_12	591157.SSLG_01307	1.082e-40	169.0	COG1721@1|root,COG1721@2|Bacteria,2GIWE@201174|Actinobacteria	201174|Actinobacteria	J	protein some members contain a von Willebrand factor type A vWA domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
BYD2_k127_5279329_4	103733.JNYO01000085_gene6	4.451e-111	368.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4DYG2@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM ATPase family associated with various cellular activities (AAA)	yeaC	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
BYD2_k127_5279329_6	1313172.YM304_36430	6.303e-85	291.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
BYD2_k127_5331333_8	211165.AJLN01000101_gene4377	5.229e-34	143.0	COG0204@1|root,COG0204@2|Bacteria,1G0ER@1117|Cyanobacteria	1117|Cyanobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DAGAT
BYD2_k127_5331333_1	298653.Franean1_0113	3.736e-153	517.0	COG1033@1|root,COG1033@2|Bacteria,2I731@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_5331333_0	644283.Micau_1247	5.659e-206	683.0	COG0028@1|root,COG0028@2|Bacteria,2GM6Y@201174|Actinobacteria,4DA3Q@85008|Micromonosporales	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvG	GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1820	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
BYD2_k127_5331333_5	1229780.BN381_130180	3.373e-106	363.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria	2|Bacteria	Q	Belongs to the long-chain O-acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,SCP2,WES_acyltransf
BYD2_k127_5331333_4	1229780.BN381_130179	6.299e-112	372.0	COG2267@1|root,COG2267@2|Bacteria,2I6HT@201174|Actinobacteria	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_5331333_7	1120954.ATXE01000001_gene1883	7.959e-44	184.0	COG0590@1|root,COG0590@2|Bacteria,2IM3Z@201174|Actinobacteria,4DQP2@85009|Propionibacteriales	201174|Actinobacteria	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.1,3.5.4.33	ko:K01485,ko:K11991	ko00240,ko00330,ko01100,map00240,map00330,map01100	-	R00974,R01411,R02922,R10223	RC00074,RC00477,RC00514,RC00809	ko00000,ko00001,ko01000,ko03016	-	-	-	MafB19-deam,dCMP_cyt_deam_1
BYD2_k127_5331333_3	1394178.AWOO02000022_gene7145	3.424e-128	440.0	COG1167@1|root,COG1167@2|Bacteria,2GITW@201174|Actinobacteria,4EFJQ@85012|Streptosporangiales	201174|Actinobacteria	EK	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
BYD2_k127_5331333_6	931626.Awo_c20220	3.909e-47	183.0	COG0727@1|root,COG0727@2|Bacteria	2|Bacteria	S	metal cluster binding	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
BYD2_k127_5331333_2	1120959.ATXF01000010_gene185	2.438e-142	466.0	COG0671@1|root,COG0671@2|Bacteria,2I8WW@201174|Actinobacteria	201174|Actinobacteria	I	COG3209 Rhs family protein	-	-	-	-	-	-	-	-	-	-	-	-	PAP2
BYD2_k127_5331333_9	525368.HMPREF0591_4650	7.61e-26	111.0	COG3335@1|root,COG3335@2|Bacteria,2GJQI@201174|Actinobacteria,234RT@1762|Mycobacteriaceae	201174|Actinobacteria	L	DDE superfamily endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	DDE_3,HTH_28,HTH_29,HTH_32
BYD2_k127_5331333_10	1440053.JOEI01000050_gene1430	4.902e-17	80.0	COG0574@1|root,COG3848@1|root,COG0574@2|Bacteria,COG3848@2|Bacteria,2GMN4@201174|Actinobacteria	201174|Actinobacteria	G	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	-	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PPDK_N
BYD2_k127_5358874_20	1240349.ANGC01000076_gene4862	6.412e-07	57.0	COG2267@1|root,COG2267@2|Bacteria,2HHTI@201174|Actinobacteria,4G0DM@85025|Nocardiaceae	201174|Actinobacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_5358874_21	1158760.AQXP01000022_gene386	3.657e-06	55.0	COG0491@1|root,COG0491@2|Bacteria,1MX4H@1224|Proteobacteria,1S56F@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
BYD2_k127_5358874_9	1449346.JQMO01000003_gene2423	2.067e-36	158.0	COG3899@1|root,COG3899@2|Bacteria,2HEUH@201174|Actinobacteria,2M5KT@2063|Kitasatospora	201174|Actinobacteria	T	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16
BYD2_k127_5358874_0	1037409.BJ6T_56240	8.538e-108	374.0	COG2114@1|root,COG2267@1|root,COG2114@2|Bacteria,COG2267@2|Bacteria,1NIJG@1224|Proteobacteria,2U09P@28211|Alphaproteobacteria,3JTK8@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IT	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Guanylate_cyc,Hydrolase_4,Trans_reg_C
BYD2_k127_5358874_4	477641.MODMU_2525	3.412e-67	241.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_5358874_1	1283299.AUKG01000001_gene3390	1.725e-102	342.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4CS9C@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_5358874_14	1173026.Glo7428_4839	5.016e-21	100.0	COG2329@1|root,COG2329@2|Bacteria	2|Bacteria	S	heme oxygenase (decyclizing) activity	-	-	1.13.12.21	ko:K15969	ko01057,ko01130,map01057,map01130	M00783	R06700	RC01658	ko00000,ko00001,ko00002,ko01000	-	-	-	ABM
BYD2_k127_5358874_16	557599.MKAN_23330	4.85e-12	76.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,2396T@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5358874_18	1454004.AW11_03294	8.81e-09	60.0	COG2801@1|root,COG2801@2|Bacteria,1PBHA@1224|Proteobacteria,2VKPT@28216|Betaproteobacteria	28216|Betaproteobacteria	L	PFAM Integrase catalytic region	-	-	-	-	-	-	-	-	-	-	-	-	rve
BYD2_k127_5358874_10	479431.Namu_4632	1.527e-34	139.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4ES3E@85013|Frankiales	201174|Actinobacteria	L	PFAM transposase IS204 IS1001 IS1096 IS1165 family protein	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
BYD2_k127_5358874_17	321955.AAGP01000050_gene3735	1.422e-11	70.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,4F8YS@85019|Brevibacteriaceae	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
BYD2_k127_5358874_8	426716.JOAJ01000001_gene309	4.363e-41	156.0	COG2801@1|root,COG2801@2|Bacteria,2GKW1@201174|Actinobacteria,4FWER@85025|Nocardiaceae	201174|Actinobacteria	L	PFAM Integrase catalytic	-	-	-	-	-	-	-	-	-	-	-	-	rve,rve_2
BYD2_k127_5358874_15	479432.Sros_6291	2.392e-18	84.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4EH3N@85012|Streptosporangiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
BYD2_k127_5358874_3	479434.Sthe_0342	2.955e-67	238.0	COG1018@1|root,COG1018@2|Bacteria,2G7Q7@200795|Chloroflexi	200795|Chloroflexi	C	PFAM oxidoreductase FAD NAD(P)-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
BYD2_k127_5358874_19	1380355.JNIJ01000039_gene5414	2.527e-08	63.0	COG3293@1|root,COG3293@2|Bacteria	2|Bacteria	L	Transposase	-	-	-	ko:K07492	-	-	-	-	ko00000	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
BYD2_k127_5358874_7	253839.SSNG_07163	2.448e-45	174.0	COG3293@1|root,COG3293@2|Bacteria,2GMT0@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_2,DUF4096
BYD2_k127_5358874_2	671143.DAMO_2372	2.76e-99	344.0	COG0778@1|root,COG0778@2|Bacteria,2NPP2@2323|unclassified Bacteria	2|Bacteria	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_5358874_12	298655.KI912267_gene7268	9.394e-33	141.0	COG0683@1|root,COG0683@2|Bacteria,2H1ZK@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
BYD2_k127_5358874_13	1232410.KI421416_gene2675	2.779e-24	107.0	COG0599@1|root,COG0599@2|Bacteria,1N2ZQ@1224|Proteobacteria,42VDR@68525|delta/epsilon subdivisions,2WRKS@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM Carboxymuconolactone decarboxylase	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_5358874_6	266117.Rxyl_2792	2.219e-55	201.0	COG0819@1|root,COG0819@2|Bacteria,2IGXQ@201174|Actinobacteria	201174|Actinobacteria	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway. Thus, catalyzes the conversion of 4-amino-5-aminomethyl-2-methylpyrimidine to 4-amino- 5-hydroxymethyl-2-methylpyrimidine (HMP)	-	-	-	ko:K20896	ko00730,ko01100,map00730,map01100	-	R09993,R11313	RC00197,RC02832	ko00000,ko00001,ko01000	-	-	-	TENA_THI-4
BYD2_k127_5358874_5	644966.Tmar_1325	4.912e-63	226.0	COG0819@1|root,COG0819@2|Bacteria,1TPK0@1239|Firmicutes,249B1@186801|Clostridia	186801|Clostridia	K	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway	tenA	-	3.5.99.2	ko:K03707	ko00730,ko01100,map00730,map01100	-	R02133,R09993	RC00224,RC00652,RC02832	ko00000,ko00001,ko01000,ko03000	-	-	-	TENA_THI-4
BYD2_k127_5358874_11	222534.KB893672_gene3028	3.776e-33	132.0	COG2267@1|root,COG2267@2|Bacteria,2GM56@201174|Actinobacteria,4ERMC@85013|Frankiales	201174|Actinobacteria	I	PFAM Alpha beta hydrolase	cpo	-	1.11.1.10	ko:K00433	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_1
BYD2_k127_5446248_18	1385519.N801_12310	9.094e-46	167.0	COG1274@1|root,COG1274@2|Bacteria,2GJH3@201174|Actinobacteria,4FE6J@85021|Intrasporangiaceae	201174|Actinobacteria	H	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle	pckG	-	4.1.1.32	ko:K01596	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko03320,ko04068,ko04151,ko04152,ko04910,ko04920,ko04922,ko04931,ko04964,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map03320,map04068,map04151,map04152,map04910,map04920,map04922,map04931,map04964	M00003	R00431,R00726	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_C,PEPCK_N
BYD2_k127_5446248_19	1123319.AUBE01000007_gene3637	5.153e-42	159.0	COG0071@1|root,COG0071@2|Bacteria,2IHVJ@201174|Actinobacteria	201174|Actinobacteria	O	Belongs to the small heat shock protein (HSP20) family	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
BYD2_k127_5446248_25	351607.Acel_1585	7.313e-31	123.0	COG1522@1|root,COG1522@2|Bacteria,2IQ4Z@201174|Actinobacteria,4ET4W@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein AsnC Lrp family	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg
BYD2_k127_5446248_23	1229780.BN381_10335	3.881e-35	137.0	291CY@1|root,2ZNZT@2|Bacteria,2HDEE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5446248_20	479431.Namu_3377	5.57e-42	156.0	COG2329@1|root,COG2329@2|Bacteria,2IM1Q@201174|Actinobacteria,4ETDY@85013|Frankiales	201174|Actinobacteria	S	PFAM Antibiotic biosynthesis monooxygenase	-	-	1.14.99.57	ko:K21481	-	-	-	-	ko00000,ko01000	-	-	-	ABM
BYD2_k127_5446248_16	512565.AMIS_16380	4.002e-54	210.0	COG4912@1|root,COG4912@2|Bacteria,2GNQD@201174|Actinobacteria,4DCZ3@85008|Micromonosporales	201174|Actinobacteria	L	DNA alkylation repair enzyme	alkD	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
BYD2_k127_5446248_9	1125971.ASJB01000065_gene6207	2.133e-91	312.0	COG2120@1|root,COG2120@2|Bacteria,2GIUS@201174|Actinobacteria,4DZX7@85010|Pseudonocardiales	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
BYD2_k127_5446248_22	1394178.AWOO02000029_gene4598	5.464e-36	151.0	COG4221@1|root,COG4221@2|Bacteria,2GQNJ@201174|Actinobacteria,4EIKG@85012|Streptosporangiales	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_5446248_1	1229780.BN381_10333	5.61e-186	587.0	COG1804@1|root,COG1804@2|Bacteria,2GKNX@201174|Actinobacteria,3UWNW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	CoA-transferase family III	-	-	5.1.99.4	ko:K01796	ko00120,ko01100,ko04146,map00120,map01100,map04146	M00104	R08734,R08739	RC02345	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
BYD2_k127_5446248_11	1449976.KALB_82	3.588e-79	276.0	COG2021@1|root,COG2021@2|Bacteria,2I3NA@201174|Actinobacteria,4DZ1P@85010|Pseudonocardiales	201174|Actinobacteria	E	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_4
BYD2_k127_5446248_12	309801.trd_0412	5.626e-78	272.0	COG2141@1|root,COG2141@2|Bacteria,2GB6V@200795|Chloroflexi,27XHN@189775|Thermomicrobia	189775|Thermomicrobia	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_5446248_6	1313172.YM304_17870	4.737e-98	328.0	COG1085@1|root,COG1085@2|Bacteria,2IJIM@201174|Actinobacteria	201174|Actinobacteria	C	Galactose-1-phosphate uridyl transferase, N-terminal domain	-	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_transf
BYD2_k127_5446248_10	1229780.BN381_10324	1.439e-82	285.0	COG0153@1|root,COG0153@2|Bacteria,2GJXI@201174|Actinobacteria,3UWRM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Belongs to the GHMP kinase family	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
BYD2_k127_5446248_15	1313172.YM304_23360	2.346e-54	213.0	COG0614@1|root,COG0614@2|Bacteria,2GYJE@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type Fe3 -hydroxamate transport system, periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_2
BYD2_k127_5446248_14	1313172.YM304_23350	7.029e-63	222.0	COG3428@1|root,COG3428@2|Bacteria,2HGDA@201174|Actinobacteria,4CNBH@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT,bPH_2
BYD2_k127_5446248_21	590998.Celf_3174	8.353e-40	150.0	COG3824@1|root,COG3824@2|Bacteria,2IKXW@201174|Actinobacteria,4F2GI@85016|Cellulomonadaceae	201174|Actinobacteria	S	Zincin-like metallopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_1
BYD2_k127_5446248_4	526225.Gobs_4232	9.439e-105	376.0	COG0210@1|root,COG0210@2|Bacteria,2GKRW@201174|Actinobacteria,4ES82@85013|Frankiales	201174|Actinobacteria	L	PFAM UvrD REP helicase	uvrD2	GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0006996,GO:0008094,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0040007,GO:0042623,GO:0043167,GO:0043169,GO:0046872,GO:0051276,GO:0071103,GO:0071840,GO:0140097	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HRDC,UvrD-helicase,UvrD_C
BYD2_k127_5446248_17	1229780.BN381_10319	9.403e-48	180.0	COG2050@1|root,COG2050@2|Bacteria,2I11Y@201174|Actinobacteria,3UXR4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_5446248_7	1313172.YM304_23330	4.788e-93	313.0	COG0708@1|root,COG0708@2|Bacteria,2GKEW@201174|Actinobacteria,4CN0I@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Endonuclease/Exonuclease/phosphatase family	xthA	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
BYD2_k127_5446248_8	1313172.YM304_23320	4.482e-92	324.0	COG0539@1|root,COG0539@2|Bacteria,2I7V9@201174|Actinobacteria	201174|Actinobacteria	J	Zc3h12a-like Ribonuclease NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	HC2,RNase_Zc3h12a
BYD2_k127_5446248_2	1123024.AUII01000021_gene69	1.459e-182	580.0	COG0624@1|root,COG0624@2|Bacteria,2GKKW@201174|Actinobacteria	201174|Actinobacteria	E	COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
BYD2_k127_5446248_13	1282876.BAOK01000002_gene22	4.625e-69	240.0	COG1011@1|root,COG1011@2|Bacteria,1Q69X@1224|Proteobacteria,2TTTP@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	hydrolase	MA20_23095	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2
BYD2_k127_5446248_3	1229780.BN381_80295	5.838e-167	532.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
BYD2_k127_5446248_5	1160718.SU9_01610	1.633e-99	368.0	COG2227@1|root,COG2227@2|Bacteria,2GNRH@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase type 12	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
BYD2_k127_5446248_0	351607.Acel_0586	6.97e-322	1006.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria,4ES2Q@85013|Frankiales	201174|Actinobacteria	C	TIGRFAM 2-oxoglutarate dehydrogenase, E1	kgd	-	1.2.4.2,4.1.1.71	ko:K00164,ko:K01616	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
BYD2_k127_5503730_2	1229780.BN381_80028	3.022e-136	449.0	COG0260@1|root,COG0260@2|Bacteria,2GJRB@201174|Actinobacteria,3UWAR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
BYD2_k127_5503730_3	1127134.NOCYR_3410	3.979e-127	445.0	COG3559@1|root,COG3559@2|Bacteria,2GMSI@201174|Actinobacteria,4FU1D@85025|Nocardiaceae	201174|Actinobacteria	M	ABC transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
BYD2_k127_5503730_1	1380347.JNII01000007_gene31	9.719e-145	464.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4ESBI@85013|Frankiales	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_5503730_6	1313172.YM304_10970	1.719e-77	268.0	COG1968@1|root,COG1968@2|Bacteria,2GJVG@201174|Actinobacteria	201174|Actinobacteria	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
BYD2_k127_5503730_0	405948.SACE_7066	6.414e-208	668.0	COG3525@1|root,COG3525@2|Bacteria,2GM4H@201174|Actinobacteria,4DZWB@85010|Pseudonocardiales	201174|Actinobacteria	G	beta-N-acetylglucosaminidase	-	-	3.2.1.35	ko:K01197	ko00531,ko01100,map00531,map01100	M00076,M00077	R07824,R07825,R10905	-	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	-	-	F5_F8_type_C,Glyco_hydro_20b,NAGidase
BYD2_k127_5503730_7	1313172.YM304_29090	2.037e-42	164.0	2BJWW@1|root,32E9A@2|Bacteria,2HGG7@201174|Actinobacteria,4CNDN@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5503730_5	1229780.BN381_10108	2.372e-87	308.0	COG0846@1|root,COG0846@2|Bacteria,2GJI3@201174|Actinobacteria,3UWT0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sir2 family	cobB2	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
BYD2_k127_5503730_4	1313172.YM304_28580	2.205e-90	313.0	COG2244@1|root,COG2244@2|Bacteria	2|Bacteria	S	polysaccharide biosynthetic process	-	GO:0003674,GO:0005488,GO:0005575,GO:0005576,GO:0008150,GO:0009987,GO:0044764,GO:0046812,GO:0051704	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	Polysacc_synt,Polysacc_synt_3
BYD2_k127_5503730_8	1313172.YM304_29030	3.527e-12	70.0	COG0476@1|root,COG0607@1|root,COG0476@2|Bacteria,COG0607@2|Bacteria,2GJB6@201174|Actinobacteria,4CMRS@84992|Acidimicrobiia	84992|Acidimicrobiia	HP	ThiF family	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese,ThiF
BYD2_k127_5509249_8	298653.Franean1_3778	2.158e-31	126.0	COG2380@1|root,COG2380@2|Bacteria,2I8F9@201174|Actinobacteria,4EUZQ@85013|Frankiales	201174|Actinobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5509249_2	1137271.AZUM01000001_gene884	1.524e-99	336.0	COG0500@1|root,COG2226@2|Bacteria,2GRM0@201174|Actinobacteria,4E376@85010|Pseudonocardiales	201174|Actinobacteria	Q	O-methyltransferase	-	-	-	ko:K21255	ko01059,ko01130,map01059,map01130	M00833,M00834	R11413	RC00003,RC00392	ko00000,ko00001,ko00002,ko01000	-	-	-	Dimerisation2,Methyltransf_2
BYD2_k127_5509249_3	710111.FraQA3DRAFT_2925	7.075e-93	312.0	COG0613@1|root,COG0613@2|Bacteria,2GIZ5@201174|Actinobacteria,4ERIA@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3097)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3097
BYD2_k127_5509249_1	1121877.JQKF01000038_gene1818	2.621e-144	482.0	COG0488@1|root,COG0488@2|Bacteria,2GJ5M@201174|Actinobacteria,4CNGN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	ATPases associated with a variety of cellular activities	-	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran
BYD2_k127_5509249_10	58123.JOFJ01000027_gene2779	2.788e-11	70.0	2EQY7@1|root,33IHV@2|Bacteria,2I34U@201174|Actinobacteria,4ER5N@85012|Streptosporangiales	201174|Actinobacteria	S	Putative transmembrane protein (PGPGW)	-	-	-	-	-	-	-	-	-	-	-	-	PGPGW
BYD2_k127_5509249_7	1229780.BN381_130173	4.846e-58	217.0	COG0694@1|root,COG0694@2|Bacteria	2|Bacteria	O	iron-sulfur cluster assembly	nfuA	-	-	ko:K07400	-	-	-	-	ko00000	-	-	-	Nfu_N,NifU
BYD2_k127_5509249_0	1229780.BN381_90078	1.023e-251	790.0	COG1154@1|root,COG1154@2|Bacteria,2GMFA@201174|Actinobacteria,3UW82@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
BYD2_k127_5509249_4	1217720.ALOX01000087_gene3033	3.786e-82	285.0	COG4427@1|root,COG4427@2|Bacteria,1R4EV@1224|Proteobacteria,2TRVP@28211|Alphaproteobacteria,2JWMB@204441|Rhodospirillales	204441|Rhodospirillales	S	Uncharacterized protein conserved in bacteria (DUF2332)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2332
BYD2_k127_5509249_6	1313172.YM304_10870	1.55e-63	241.0	COG0671@1|root,COG0671@2|Bacteria,2GMYU@201174|Actinobacteria	201174|Actinobacteria	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
BYD2_k127_5509249_5	1229780.BN381_90077	3.946e-69	248.0	COG0392@1|root,COG0392@2|Bacteria	2|Bacteria	M	lysyltransferase activity	-	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
BYD2_k127_5509249_11	1157632.AQWQ01000014_gene3529	0.0002009	53.0	2DPU0@1|root,333DA@2|Bacteria,2IARZ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5509249_9	1122247.C731_3882	3.022e-26	113.0	COG1051@1|root,COG1051@2|Bacteria,2IK26@201174|Actinobacteria,23DC5@1762|Mycobacteriaceae	201174|Actinobacteria	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_5512338_6	1313172.YM304_22230	1.123e-70	247.0	COG0204@1|root,COG0204@2|Bacteria,2IAXZ@201174|Actinobacteria,4CN1J@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
BYD2_k127_5512338_11	2074.JNYD01000024_gene2834	2.905e-14	83.0	2BTY3@1|root,32P6C@2|Bacteria,2I8RQ@201174|Actinobacteria,4ECZJ@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_5512338_9	2074.JNYD01000024_gene2833	8.825e-34	143.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,4EBV9@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_5512338_10	471853.Bcav_0244	3.716e-16	89.0	2FEXV@1|root,346WK@2|Bacteria,2GVWC@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5512338_7	926564.KI911740_gene3527	2.451e-62	223.0	2C30W@1|root,33T8Q@2|Bacteria,2H1UH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K00127	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001	-	-	-	Ni_hydr_CYTB
BYD2_k127_5512338_1	1313172.YM304_25250	3.016e-118	401.0	COG2303@1|root,COG2303@2|Bacteria,2GJKS@201174|Actinobacteria	201174|Actinobacteria	E	Oxidoreductase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N,Gluconate_2-dh3
BYD2_k127_5512338_5	1313172.YM304_25240	3.191e-90	324.0	COG0451@1|root,COG0451@2|Bacteria	2|Bacteria	GM	ADP-glyceromanno-heptose 6-epimerase activity	JD73_00815	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
BYD2_k127_5512338_3	1313172.YM304_25230	8.074e-108	377.0	COG0451@1|root,COG0451@2|Bacteria,2GMHH@201174|Actinobacteria	201174|Actinobacteria	M	3-beta hydroxysteroid dehydrogenase isomerase	-	-	-	ko:K21793	ko00333,ko01130,map00333,map01130	M00838	R11663,R11666	-	ko00000,ko00001,ko00002	-	-	-	Epimerase
BYD2_k127_5512338_4	1313172.YM304_25140	1.651e-101	356.0	28TMQ@1|root,33S62@2|Bacteria,2H3TK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5512338_2	1313172.YM304_25140	8.048e-110	382.0	28TMQ@1|root,33S62@2|Bacteria,2H3TK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5512338_0	309801.trd_1105	0.0	1243.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,2G5VK@200795|Chloroflexi,27Z18@189775|Thermomicrobia	189775|Thermomicrobia	E	GXGXG motif	-	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
BYD2_k127_5512338_8	1122239.AULS01000006_gene198	2.23e-36	156.0	COG0515@1|root,COG0515@2|Bacteria,2GIW5@201174|Actinobacteria,4FM8Q@85023|Microbacteriaceae	201174|Actinobacteria	KLT	Protein tyrosine kinase	pknK	-	-	-	-	-	-	-	-	-	-	-	Pkinase
BYD2_k127_5524561_0	1150864.MILUP08_40910	6.374e-255	813.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4DAF0@85008|Micromonosporales	201174|Actinobacteria	V	ABC transporter	yfiC	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_5524561_1	479432.Sros_8741	7.703e-228	725.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EHPN@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_5524561_8	33876.JNXY01000009_gene8886	3.651e-97	350.0	COG0642@1|root,COG2205@2|Bacteria,2I2WT@201174|Actinobacteria,4DBZG@85008|Micromonosporales	201174|Actinobacteria	T	Nitrate and nitrite sensing	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_5524561_13	58123.JOFJ01000014_gene5022	8.243e-47	179.0	COG0640@1|root,COG0640@2|Bacteria,2IM1K@201174|Actinobacteria,4EJG2@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_5524561_11	172088.AUGA01000015_gene2865	6.25e-61	217.0	COG3832@1|root,COG3832@2|Bacteria,1R68R@1224|Proteobacteria,2TTYQ@28211|Alphaproteobacteria,3JT78@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_5524561_15	365528.KB891126_gene3198	8.421e-08	55.0	COG2050@1|root,COG2050@2|Bacteria,2H2K4@201174|Actinobacteria	201174|Actinobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_5524561_12	298655.KI912266_gene5954	1.709e-48	184.0	COG2141@1|root,COG2141@2|Bacteria,2IB10@201174|Actinobacteria,4ET8S@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_5524561_2	298654.FraEuI1c_3304	6.363e-192	607.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_5524561_4	285535.JOEY01000006_gene8111	1.973e-153	499.0	COG0318@1|root,COG0318@2|Bacteria,2GJYP@201174|Actinobacteria	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_5524561_14	1343740.M271_49470	1.374e-27	115.0	2ECT0@1|root,336QK@2|Bacteria,2IKM4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5524561_3	1172186.KB911469_gene2554	9.542e-154	497.0	COG1024@1|root,COG1024@2|Bacteria,2GKNU@201174|Actinobacteria,233FU@1762|Mycobacteriaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_5524561_6	298655.KI912266_gene5836	3.197e-127	422.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_5524561_7	262316.MAP_3261c	1.821e-101	337.0	COG4221@1|root,COG4221@2|Bacteria,2GK52@201174|Actinobacteria,23684@1762|Mycobacteriaceae	201174|Actinobacteria	S	COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_5524561_5	487521.OCU_13290	1.444e-142	465.0	COG2124@1|root,COG2124@2|Bacteria,2GNJI@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_5524561_9	235985.BBPN01000006_gene3586	9.653e-88	297.0	COG1024@1|root,COG1024@2|Bacteria,2GJY4@201174|Actinobacteria,2NF6J@228398|Streptacidiphilus	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_5524561_10	298654.FraEuI1c_4140	9.749e-77	261.0	COG0410@1|root,COG0410@2|Bacteria,2IH68@201174|Actinobacteria	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_5533115_15	1229780.BN381_10242	2.24e-49	188.0	COG0559@1|root,COG4177@1|root,COG0559@2|Bacteria,COG4177@2|Bacteria,2GJHR@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
BYD2_k127_5533115_0	1229780.BN381_10243	6.784e-298	945.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria	201174|Actinobacteria	E	ABC transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_5533115_11	1229780.BN381_10244	2.041e-84	302.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5533115_13	1229780.BN381_10244	2.099e-78	285.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5533115_9	1229780.BN381_10244	3.848e-88	313.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5533115_18	526225.Gobs_4168	1.585e-10	72.0	2DKVQ@1|root,30HQN@2|Bacteria,2GPA0@201174|Actinobacteria,4EWA0@85013|Frankiales	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
BYD2_k127_5533115_10	585531.HMPREF0063_11995	2.322e-85	295.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria,4DNVV@85009|Propionibacteriales	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_5533115_5	1229780.BN381_10294	9.159e-115	385.0	COG2733@1|root,COG2733@2|Bacteria,2GKGM@201174|Actinobacteria,3UX18@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
BYD2_k127_5533115_7	1120950.KB892745_gene2893	5.184e-106	359.0	COG0665@1|root,COG0665@2|Bacteria,2GN2M@201174|Actinobacteria,4DMY8@85009|Propionibacteriales	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	1.4.3.3	ko:K00273	ko00260,ko00311,ko00330,ko00472,ko01100,ko01130,ko04146,map00260,map00311,map00330,map00472,map01100,map01130,map04146	-	R00366,R02457,R02894,R02923,R04221,R07400	RC00006,RC00018,RC00135	ko00000,ko00001,ko01000	-	-	-	DAO
BYD2_k127_5533115_6	1298880.AUEV01000006_gene4307	9.03e-113	378.0	COG0454@1|root,COG1846@1|root,COG0456@2|Bacteria,COG1846@2|Bacteria,2GNNG@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,MarR_2
BYD2_k127_5533115_17	1032480.MLP_05490	1.557e-12	74.0	COG0494@1|root,COG0494@2|Bacteria,2IKSQ@201174|Actinobacteria,4DS3I@85009|Propionibacteriales	201174|Actinobacteria	L	nUDIX hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,NYN_YacP
BYD2_k127_5533115_1	1380390.JIAT01000014_gene6208	5.203e-288	899.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	CbiA,NB-ARC,Response_reg,TIR_2,TPR_10,TPR_12
BYD2_k127_5533115_4	1380390.JIAT01000014_gene6209	3.217e-121	399.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_5533115_14	1382359.JIAL01000001_gene78	4.11e-61	222.0	COG1917@1|root,COG2169@1|root,COG1917@2|Bacteria,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.2.2.21	ko:K02099,ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,AraC_binding,Cupin_2,Endonuclea_NS_2,HTH_18,HTH_AraC
BYD2_k127_5533115_12	1303518.CCALI_02848	2.631e-81	278.0	COG5285@1|root,COG5285@2|Bacteria	2|Bacteria	Q	dioxygenase activity	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
BYD2_k127_5533115_16	1121861.KB899914_gene2074	1.771e-43	168.0	COG5553@1|root,COG5553@2|Bacteria,1NDMC@1224|Proteobacteria,2UKAN@28211|Alphaproteobacteria,2JZ7P@204441|Rhodospirillales	204441|Rhodospirillales	S	Cysteine dioxygenase type I	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5533115_2	749927.AMED_4776	3.082e-160	543.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4E0IZ@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
BYD2_k127_5533115_3	1206737.BAGF01000151_gene6270	6.118e-132	434.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4FYN0@85025|Nocardiaceae	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
BYD2_k127_5533115_8	1313172.YM304_41880	5.338e-98	326.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CNHT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_5547979_4	525909.Afer_1676	1.116e-35	137.0	COG0292@1|root,COG0292@2|Bacteria,2IHTN@201174|Actinobacteria,4CN4X@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
BYD2_k127_5547979_8	649747.HMPREF0083_04792	1.16e-12	76.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,4HNIQ@91061|Bacilli	91061|Bacilli	J	Belongs to the bacterial ribosomal protein bL35 family	rpmI	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
BYD2_k127_5547979_2	1313172.YM304_20650	2.78e-69	243.0	COG0290@1|root,COG0290@2|Bacteria,2GJGT@201174|Actinobacteria,4CMZR@84992|Acidimicrobiia	84992|Acidimicrobiia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
BYD2_k127_5547979_7	1229780.BN381_290134	4.51e-18	94.0	2FH85@1|root,3492H@2|Bacteria,2H8HQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5547979_6	298655.KI912266_gene2326	1.468e-20	105.0	2CIS7@1|root,2ZTU5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5547979_1	1313172.YM304_20600	1.556e-117	393.0	COG0040@1|root,COG0040@2|Bacteria,2GNAX@201174|Actinobacteria,4CMTS@84992|Acidimicrobiia	84992|Acidimicrobiia	F	ATP phosphoribosyltransferase	hisG	-	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
BYD2_k127_5547979_5	45157.CMI238CT	3.124e-33	134.0	COG0054@1|root,KOG3243@2759|Eukaryota	2759|Eukaryota	H	6,7-dimethyl-8-ribityllumazine synthase activity	RIB4	GO:0000906,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005758,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019842,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031970,GO:0031974,GO:0031975,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902444	2.5.1.78,2.5.1.9,2.6.1.16	ko:K00793,ko:K00794,ko:K00820	ko00250,ko00520,ko00740,ko01100,ko01110,ko01130,ko04931,map00250,map00520,map00740,map01100,map01110,map01130,map04931	M00125	R00066,R00768,R04457	RC00010,RC00163,RC00958,RC00960,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	DMRL_synthase
BYD2_k127_5547979_0	1229780.BN381_50160	1.447e-188	603.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,2GIWJ@201174|Actinobacteria,3UWF0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
BYD2_k127_5547979_3	498761.HM1_2142	1.218e-44	165.0	COG0307@1|root,COG0307@2|Bacteria,1V1EP@1239|Firmicutes,24FVK@186801|Clostridia	186801|Clostridia	H	riboflavin synthase, alpha subunit	ribE	-	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
BYD2_k127_5556028_0	1313172.YM304_23520	6.793e-192	604.0	COG3552@1|root,COG3825@1|root,COG3552@2|Bacteria,COG3825@2|Bacteria,2GNTS@201174|Actinobacteria,4CMU1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
BYD2_k127_5556028_3	390989.JOEG01000009_gene935	1.071e-20	108.0	COG2114@1|root,COG3903@1|root,COG2114@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4DBPZ@85008|Micromonosporales	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Guanylate_cyc
BYD2_k127_5556028_2	1122963.AUHB01000009_gene1775	1.626e-96	328.0	COG1609@1|root,COG1609@2|Bacteria,1MVUR@1224|Proteobacteria,2TUPD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional regulator (LacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
BYD2_k127_5556028_1	471852.Tcur_2324	1.249e-117	402.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EMXE@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
BYD2_k127_5557361_0	345341.KUTG_06743	3.78e-144	465.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DYVW@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
BYD2_k127_5557361_1	526225.Gobs_3749	1.976e-15	85.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
BYD2_k127_5557472_0	555793.WSK_3094	7.54e-143	462.0	28IZD@1|root,2Z8WU@2|Bacteria,1NEGQ@1224|Proteobacteria,2UZGH@28211|Alphaproteobacteria,2K8TY@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5557472_6	1549858.MC45_16640	6.824e-53	196.0	28PSM@1|root,2ZCE4@2|Bacteria,1RBR6@1224|Proteobacteria,2V0GH@28211|Alphaproteobacteria,2K9CV@204457|Sphingomonadales	204457|Sphingomonadales	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5557472_2	1240349.ANGC01000003_gene2048	3.712e-82	280.0	COG1414@1|root,COG1414@2|Bacteria,2GNHA@201174|Actinobacteria,4FW7P@85025|Nocardiaceae	201174|Actinobacteria	K	helix_turn_helix isocitrate lyase regulation	pcaR	-	-	ko:K02624	-	-	-	-	ko00000,ko03000	-	-	-	HTH_IclR,IclR
BYD2_k127_5557472_4	525909.Afer_0784	1.844e-67	255.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CMU1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	VWA domain containing CoxE-like protein	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
BYD2_k127_5557472_7	345341.KUTG_00776	4.301e-49	201.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,4E1G7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BYD2_k127_5557472_8	935839.JAGJ01000008_gene1647	3.965e-40	156.0	COG3409@1|root,COG3409@2|Bacteria,2IRFZ@201174|Actinobacteria	201174|Actinobacteria	M	Putative peptidoglycan binding domain	pdcA	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
BYD2_k127_5557472_5	1459636.NTE_03221	5.93e-58	216.0	COG0500@1|root,arCOG01783@2157|Archaea	2157|Archaea	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_5557472_1	1079986.JH164861_gene7150	1.659e-131	439.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BYD2_k127_5557472_3	1229780.BN381_350067	9.687e-68	235.0	COG0086@1|root,COG0086@2|Bacteria,2GKWF@201174|Actinobacteria,3UWBS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	GO:0000428,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0030880,GO:0032991,GO:0040007,GO:0044424,GO:0044464,GO:0061695,GO:0071944,GO:1902494,GO:1990234	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
BYD2_k127_5580333_1	298655.KI912266_gene2638	1.066e-95	329.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_5580333_3	1121926.AXWO01000039_gene1700	5.812e-93	321.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria,4EYCU@85014|Glycomycetales	201174|Actinobacteria	T	PFAM histidine kinase dimerisation and phosphoacceptor region	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
BYD2_k127_5580333_2	298655.KI912266_gene2640	1.573e-93	313.0	COG1131@1|root,COG1131@2|Bacteria,2GJDP@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_5580333_8	298655.KI912266_gene2641	3.205e-55	204.0	2DKVQ@1|root,30HQN@2|Bacteria,2GPA0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_4
BYD2_k127_5580333_4	1137269.AZWL01000060_gene4879	1.126e-80	289.0	COG0577@1|root,COG0577@2|Bacteria,2GMH5@201174|Actinobacteria	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_5580333_6	525909.Afer_1310	9.874e-63	233.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4CP56@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_5580333_0	1122138.AQUZ01000019_gene8187	6.341e-243	757.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
BYD2_k127_5580333_5	1122138.AQUZ01000019_gene8186	6.188e-76	273.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4DNJC@85009|Propionibacteriales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
BYD2_k127_5580333_7	40571.JOEA01000050_gene7496	1.716e-61	228.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria,4EBUX@85010|Pseudonocardiales	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
BYD2_k127_5584492_3	1229780.BN381_110065	1.985e-27	119.0	COG0589@1|root,COG0589@2|Bacteria	2|Bacteria	T	AMP binding	-	-	-	-	-	-	-	-	-	-	-	-	Usp
BYD2_k127_5584492_0	1380390.JIAT01000010_gene4038	2.699e-151	507.0	COG0520@1|root,COG0520@2|Bacteria,2GN15@201174|Actinobacteria,4CS3P@84995|Rubrobacteria	84995|Rubrobacteria	E	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5584492_4	314271.RB2654_15135	2.165e-12	80.0	2CITB@1|root,2ZN00@2|Bacteria,1P9JA@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5584492_2	1123261.AXDW01000001_gene1223	3.846e-55	210.0	COG0446@1|root,COG0446@2|Bacteria,1QXXG@1224|Proteobacteria,1T3JA@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Sulfotransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Sulfotransfer_3
BYD2_k127_5584492_1	1123279.ATUS01000001_gene2396	3.15e-60	213.0	COG5361@1|root,COG5361@2|Bacteria,1NQYA@1224|Proteobacteria,1SJTP@1236|Gammaproteobacteria,1J97U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
BYD2_k127_5588677_11	1121267.JHZL01000028_gene1872	0.0004867	48.0	2A4CB@1|root,30SXZ@2|Bacteria,1PCGS@1224|Proteobacteria,42W82@68525|delta/epsilon subdivisions,2YQMV@29547|Epsilonproteobacteria	29547|Epsilonproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5588677_0	469383.Cwoe_4837	1.908e-202	644.0	COG2072@1|root,COG2072@2|Bacteria,2GJEA@201174|Actinobacteria,4CP9C@84995|Rubrobacteria	84995|Rubrobacteria	P	L-lysine 6-monooxygenase (NADPH-requiring)	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_3
BYD2_k127_5588677_6	298655.KI912267_gene6855	2.662e-84	287.0	COG1028@1|root,COG1028@2|Bacteria,2GKT2@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
BYD2_k127_5588677_2	1205680.CAKO01000002_gene2489	6.911e-122	407.0	COG2159@1|root,COG2159@2|Bacteria,1P6G6@1224|Proteobacteria,2TU10@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_5588677_4	1283299.AUKG01000004_gene955	6.577e-103	343.0	COG0008@1|root,COG0008@2|Bacteria,2GKMT@201174|Actinobacteria,4CP7F@84995|Rubrobacteria	84995|Rubrobacteria	J	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon	gluQ	-	6.1.1.17	ko:K01885	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
BYD2_k127_5588677_8	1209984.BN978_05870	1.454e-31	138.0	COG2114@1|root,COG2114@2|Bacteria,2GN02@201174|Actinobacteria,234WK@1762|Mycobacteriaceae	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005504,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0031406,GO:0033293,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.6.1.1	ko:K01768	ko00230,ko02025,ko04113,ko04213,map00230,map02025,map04113,map04213	M00695	R00089,R00434	RC00295	ko00000,ko00001,ko00002,ko01000	-	-	-	Ad_Cy_reg,Guanylate_cyc
BYD2_k127_5588677_9	1313172.YM304_05890	8.567e-21	94.0	2DNW5@1|root,32ZGI@2|Bacteria,2IQ5T@201174|Actinobacteria	201174|Actinobacteria	S	Rho termination factor	-	-	-	-	-	-	-	-	-	-	-	-	Rho_N
BYD2_k127_5588677_1	58123.JOFJ01000014_gene5170	2.618e-181	572.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria,4EHGY@85012|Streptosporangiales	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
BYD2_k127_5588677_7	1449044.JMLE01000007_gene1265	1.977e-39	165.0	COG0500@1|root,COG0500@2|Bacteria,2GMRI@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_5588677_5	1476876.JOJO01000002_gene6302	7.757e-94	327.0	COG2227@1|root,COG2227@2|Bacteria,2I2JK@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Methyltransf_11,Methyltransf_25
BYD2_k127_5588677_3	1146883.BLASA_1735	2.274e-120	401.0	COG1409@1|root,COG1409@2|Bacteria	2|Bacteria	S	acid phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
BYD2_k127_5588677_10	33876.JNXY01000005_gene8774	3.261e-19	104.0	2D3F0@1|root,32TEU@2|Bacteria,2IDGD@201174|Actinobacteria,4DGEV@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5599668_1	1123322.KB904691_gene4438	2.201e-21	94.0	COG0241@1|root,COG0241@2|Bacteria,2GK77@201174|Actinobacteria	201174|Actinobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Hydrolase_like
BYD2_k127_5599668_0	146922.JOFU01000084_gene4075	7.939e-81	284.0	COG2208@1|root,COG2208@2|Bacteria,2GNG4@201174|Actinobacteria	201174|Actinobacteria	KT	phosphatase	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
BYD2_k127_5599668_2	365528.KB891230_gene1865	0.0001199	44.0	COG2146@1|root,COG2146@2|Bacteria,2I1BQ@201174|Actinobacteria,4EW13@85013|Frankiales	201174|Actinobacteria	P	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231,Rieske
BYD2_k127_5630293_4	1150398.JIBJ01000003_gene1737	4.906e-176	556.0	COG0364@1|root,COG0364@2|Bacteria,2GISI@201174|Actinobacteria,1W7WN@1268|Micrococcaceae	201174|Actinobacteria	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf1	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
BYD2_k127_5630293_0	1150398.JIBJ01000003_gene1738	0.0	1073.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,1W81Y@1268|Micrococcaceae	201174|Actinobacteria	G	Glycoside hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
BYD2_k127_5630293_10	292564.Cyagr_2784	1.806e-16	87.0	COG2303@1|root,COG2303@2|Bacteria,1G2DQ@1117|Cyanobacteria,22S4T@167375|Cyanobium	1117|Cyanobacteria	E	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GMC_oxred_C,GMC_oxred_N
BYD2_k127_5630293_1	1380390.JIAT01000011_gene2351	4.123e-255	791.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria	201174|Actinobacteria	E	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,GMC_oxred_C,GMC_oxred_N
BYD2_k127_5630293_3	1150398.JIBJ01000003_gene1735	2.374e-217	709.0	COG1271@1|root,COG1271@2|Bacteria,2GJE4@201174|Actinobacteria,1W7RK@1268|Micrococcaceae	201174|Actinobacteria	C	Ubiquinol Oxidase	-	-	1.10.3.14	ko:K00425	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_I
BYD2_k127_5630293_6	1380370.JIBA01000013_gene1272	2.463e-135	441.0	COG1294@1|root,COG1294@2|Bacteria,2GMFV@201174|Actinobacteria,4FEJA@85021|Intrasporangiaceae	201174|Actinobacteria	C	Cytochrome C oxidase assembly protein	cydB	-	1.10.3.14	ko:K00426	ko00190,ko01100,ko02020,map00190,map01100,map02020	M00153	R11325	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.3	-	-	Cyt_bd_oxida_II
BYD2_k127_5630293_12	1380390.JIAT01000011_gene2362	1.21e-08	61.0	COG0599@1|root,COG0599@2|Bacteria,2HUBM@201174|Actinobacteria,4CU1B@84995|Rubrobacteria	84995|Rubrobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5630293_13	1194165.CAJF01000011_gene1032	1.058e-06	59.0	COG0599@1|root,COG0599@2|Bacteria,2GTHM@201174|Actinobacteria	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_5630293_9	1380393.JHVP01000004_gene412	1.164e-33	143.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4ETBE@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5630293_2	1380346.JNIH01000019_gene6023	1.695e-219	696.0	COG0025@1|root,COG0025@2|Bacteria,2I9RZ@201174|Actinobacteria	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger,TrkA_N
BYD2_k127_5630293_5	1283283.ATXA01000008_gene3177	3.488e-167	553.0	COG2909@1|root,COG2909@2|Bacteria,2IBM2@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,AAA_22,GerE
BYD2_k127_5630293_7	469371.Tbis_0122	6.068e-57	211.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,4E2XM@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
BYD2_k127_5630293_8	1440774.Y900_017040	2.116e-42	162.0	COG3576@1|root,COG3576@2|Bacteria,2I2U7@201174|Actinobacteria,239HD@1762|Mycobacteriaceae	201174|Actinobacteria	S	PFAM pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_5711869_7	1313172.YM304_42670	2.955e-33	137.0	2CQNK@1|root,332VM@2|Bacteria,2HGHQ@201174|Actinobacteria,4CNEW@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Family of unknown function (DUF5318)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5318
BYD2_k127_5711869_8	2074.JNYD01000004_gene4834	2.393e-22	107.0	COG1695@1|root,COG1695@2|Bacteria,2GMJM@201174|Actinobacteria,4E1NG@85010|Pseudonocardiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_5711869_0	525909.Afer_0037	4.759e-171	549.0	COG1260@1|root,COG1260@2|Bacteria,2GKHB@201174|Actinobacteria,4CNE8@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Myo-inositol-1-phosphate synthase	ino1	-	5.5.1.4	ko:K01858	ko00521,ko00562,ko01100,ko01130,map00521,map00562,map01100,map01130	-	R07324	RC01804	ko00000,ko00001,ko01000	-	-	-	Inos-1-P_synth
BYD2_k127_5711869_3	1048339.KB913029_gene3593	1.405e-99	358.0	COG2172@1|root,COG2203@1|root,COG2208@1|root,COG2172@2|Bacteria,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,4EVA5@85013|Frankiales	201174|Actinobacteria	T	Serine phosphatase RsbU, regulator of sigma subunit	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,GAF_3,HATPase_c_2,PAS_3,PAS_4,PAS_9,SpoIIE
BYD2_k127_5711869_5	1229780.BN381_100148	3.898e-38	161.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23
BYD2_k127_5711869_1	1306174.JODP01000003_gene2039	1.111e-158	519.0	COG0617@1|root,COG0617@2|Bacteria,2GMT1@201174|Actinobacteria	201174|Actinobacteria	J	tRNA nucleotidyltransferase poly(A) polymerase	pcnA	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd
BYD2_k127_5711869_2	525909.Afer_0024	1.154e-99	336.0	COG0123@1|root,COG0123@2|Bacteria,2GJUH@201174|Actinobacteria,4CMXH@84992|Acidimicrobiia	84992|Acidimicrobiia	BQ	Histone deacetylase domain	-	-	-	-	-	-	-	-	-	-	-	-	Hist_deacetyl
BYD2_k127_5711869_6	525909.Afer_0025	1.849e-34	143.0	COG0454@1|root,COG0456@2|Bacteria,2HGG5@201174|Actinobacteria,4CNDG@84992|Acidimicrobiia	84992|Acidimicrobiia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_5711869_9	526225.Gobs_5081	4.768e-19	103.0	COG3170@1|root,COG3170@2|Bacteria,2GN00@201174|Actinobacteria,4ESX8@85013|Frankiales	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5711869_4	1313172.YM304_42740	3.325e-71	250.0	COG1307@1|root,COG1307@2|Bacteria,2GIUV@201174|Actinobacteria,4CN2K@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein, DegV family COG1307	-	-	-	-	-	-	-	-	-	-	-	-	DegV
BYD2_k127_5731736_10	67281.JNZZ01000013_gene1907	5.835e-110	361.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,41C8J@629295|Streptomyces griseus group	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA11	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
BYD2_k127_5731736_32	675635.Psed_3981	3.158e-11	77.0	COG1042@1|root,COG1247@1|root,COG1042@2|Bacteria,COG1247@2|Bacteria,2GKN1@201174|Actinobacteria,4DYY0@85010|Pseudonocardiales	201174|Actinobacteria	CK	Acyl-CoA synthetase (NDP forming)	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_5,Acetyltransf_1,Acetyltransf_3,CoA_binding_2,Succ_CoA_lig
BYD2_k127_5731736_9	1123320.KB889585_gene1891	1e-134	439.0	COG1960@1|root,COG1960@2|Bacteria,2I8MN@201174|Actinobacteria	201174|Actinobacteria	C	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
BYD2_k127_5731736_24	479433.Caci_5359	6.57e-54	214.0	COG2030@1|root,COG2030@2|Bacteria,2IPFP@201174|Actinobacteria	201174|Actinobacteria	I	MaoC like domain	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydratas
BYD2_k127_5731736_19	479433.Caci_5358	2.947e-67	255.0	COG2030@1|root,COG2030@2|Bacteria,2ICZR@201174|Actinobacteria	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
BYD2_k127_5731736_8	1123320.KB889585_gene1894	4.522e-139	453.0	COG1804@1|root,COG1804@2|Bacteria,2IEU2@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
BYD2_k127_5731736_3	1123320.KB889585_gene1895	3.855e-199	626.0	COG1960@1|root,COG1960@2|Bacteria,2ICK3@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_5731736_1	1120950.KB892709_gene4112	8.71e-212	676.0	COG1233@1|root,COG1233@2|Bacteria,2GMUC@201174|Actinobacteria,4DPDC@85009|Propionibacteriales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,DAO,NAD_binding_8
BYD2_k127_5731736_6	1089545.KB913037_gene9525	1.395e-168	539.0	COG3285@1|root,COG3285@2|Bacteria,2GM0A@201174|Actinobacteria,4DY4T@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA primase, small subunit	ligD	-	-	-	-	-	-	-	-	-	-	-	DNA_primase_S
BYD2_k127_5731736_28	1229780.BN381_780003	1.925e-47	174.0	COG2050@1|root,COG2050@2|Bacteria	2|Bacteria	Q	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_5731736_25	1123322.KB904691_gene4448	3.648e-52	205.0	COG2890@1|root,COG2890@2|Bacteria,2ICD8@201174|Actinobacteria	201174|Actinobacteria	J	CheR methyltransferase, SAM binding domain	-	-	-	ko:K21786	ko00333,ko01130,map00333,map01130	M00837,M00838	R11670	-	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
BYD2_k127_5731736_7	1449353.JQMQ01000005_gene5520	4.275e-152	491.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,2NEQU@228398|Streptacidiphilus	201174|Actinobacteria	C	CoA-transferase family III	-	-	2.8.3.15	ko:K07544	ko00623,ko01100,ko01120,ko01220,map00623,map01100,map01120,map01220	M00418	R05588	RC00014,RC00137	ko00000,ko00001,ko00002,ko01000	-	-	-	CoA_transf_3
BYD2_k127_5731736_12	479434.Sthe_2396	1.448e-84	303.0	COG1807@1|root,COG1807@2|Bacteria,2G85B@200795|Chloroflexi	200795|Chloroflexi	M	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
BYD2_k127_5731736_5	1123320.KB889747_gene7183	3.394e-171	549.0	COG1545@1|root,COG3425@1|root,COG1545@2|Bacteria,COG3425@2|Bacteria,2GP7R@201174|Actinobacteria	201174|Actinobacteria	I	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	ACP_syn_III_C,DUF35_N,OB_aCoA_assoc
BYD2_k127_5731736_2	1123320.KB889747_gene7184	2.561e-205	649.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_5731736_26	1313172.YM304_13660	1.503e-51	193.0	COG1846@1|root,COG1846@2|Bacteria,2GMDI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5731736_4	298655.KI912266_gene5041	1.634e-182	583.0	COG0318@1|root,COG0318@2|Bacteria,2I91U@201174|Actinobacteria	201174|Actinobacteria	IQ	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_5731736_0	298655.KI912266_gene5581	1.861e-213	668.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_5731736_14	1068980.ARVW01000001_gene5648	5.259e-77	268.0	COG0346@1|root,COG0346@2|Bacteria,2GMTB@201174|Actinobacteria,4E3U9@85010|Pseudonocardiales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5731736_27	287986.DV20_09530	1.765e-49	182.0	2C9IE@1|root,31AT3@2|Bacteria,2IM6M@201174|Actinobacteria,4E4GK@85010|Pseudonocardiales	201174|Actinobacteria	S	Domain of unknown function (DUF4383)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4383
BYD2_k127_5731736_11	402881.Plav_0222	1.223e-99	332.0	COG1024@1|root,COG1024@2|Bacteria,1RA5T@1224|Proteobacteria,2UP3E@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_5731736_22	479433.Caci_8742	2.658e-63	225.0	COG1335@1|root,COG1335@2|Bacteria,2I81Y@201174|Actinobacteria	201174|Actinobacteria	Q	isochorismatase	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
BYD2_k127_5731736_17	935866.JAER01000033_gene3639	2.485e-70	257.0	COG2141@1|root,COG2141@2|Bacteria,2GJT1@201174|Actinobacteria,4DU0S@85009|Propionibacteriales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_5731736_16	298655.KI912266_gene5601	3.768e-71	248.0	COG1309@1|root,COG1309@2|Bacteria,2GK0V@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_5731736_23	1206101.AZXC01000007_gene2541	1.042e-58	214.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_5731736_13	1394178.AWOO02000049_gene6167	5.065e-78	289.0	COG1028@1|root,COG1028@2|Bacteria,2IGF6@201174|Actinobacteria,4ENNU@85012|Streptosporangiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_5731736_20	330084.JNYZ01000029_gene137	4.191e-66	231.0	COG2128@1|root,COG2128@2|Bacteria,2IAT6@201174|Actinobacteria,4EEYQ@85010|Pseudonocardiales	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_5731736_33	430998.XP_007676376.1	2.3e-09	65.0	2EQNK@1|root,2STMR@2759|Eukaryota,3A9GP@33154|Opisthokonta,3P6PU@4751|Fungi,3QYZP@4890|Ascomycota,203AU@147541|Dothideomycetes	4751|Fungi	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
BYD2_k127_5731736_18	1121033.AUCF01000015_gene1462	8.877e-68	242.0	COG1011@1|root,COG1011@2|Bacteria,1MX48@1224|Proteobacteria,2TUWQ@28211|Alphaproteobacteria,2JRW8@204441|Rhodospirillales	204441|Rhodospirillales	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
BYD2_k127_5731736_30	1382356.JQMP01000001_gene1112	1.032e-38	160.0	COG4454@1|root,COG4454@2|Bacteria,2GBEQ@200795|Chloroflexi,27Z6N@189775|Thermomicrobia	189775|Thermomicrobia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5731736_15	1122939.ATUD01000001_gene232	2.095e-71	246.0	COG2818@1|root,COG2818@2|Bacteria,2IFH0@201174|Actinobacteria,4CRW2@84995|Rubrobacteria	84995|Rubrobacteria	L	Methyladenine glycosylase	-	-	-	-	-	-	-	-	-	-	-	-	Adenine_glyco
BYD2_k127_5731736_21	1123320.KB889685_gene2189	1.114e-64	235.0	28K5H@1|root,2Z9U4@2|Bacteria,2GKEQ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5731736_29	298654.FraEuI1c_2882	8.905e-47	169.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EU00@85013|Frankiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_5747116_1	1128421.JAGA01000002_gene634	5.387e-128	420.0	COG3185@1|root,COG3185@2|Bacteria	2|Bacteria	E	4-Hydroxyphenylpyruvate dioxygenase	hpd	GO:0003674,GO:0003824,GO:0003868,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0051213,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606	1.13.11.27,1.13.11.46	ko:K00457,ko:K16421	ko00130,ko00261,ko00350,ko00360,ko01055,ko01100,ko01130,map00130,map00261,map00350,map00360,map01055,map01100,map01130	M00044	R01372,R02521,R06632	RC00505,RC00738,RC01471	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Glyoxalase,Glyoxalase_5
BYD2_k127_5747116_3	1449347.JQLN01000002_gene2238	1.361e-47	177.0	COG1522@1|root,COG1522@2|Bacteria,2H7NM@201174|Actinobacteria,2M2U8@2063|Kitasatospora	201174|Actinobacteria	K	Lrp/AsnC ligand binding domain	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
BYD2_k127_5747116_0	251229.Chro_5229	9.61e-268	855.0	COG0506@1|root,COG1012@1|root,COG0506@2|Bacteria,COG1012@2|Bacteria,1G217@1117|Cyanobacteria,3VIB4@52604|Pleurocapsales	1117|Cyanobacteria	CE	Belongs to the aldehyde dehydrogenase family	putA	-	1.2.1.88,1.5.5.2	ko:K13821	ko00250,ko00330,ko01100,ko01110,ko01130,map00250,map00330,map01100,map01110,map01130	-	R00245,R00707,R00708,R01253,R04444,R04445,R05051	RC00080,RC00083,RC00216,RC00242,RC00255	ko00000,ko00001,ko01000,ko03000	-	-	-	Aldedh,Pro_dh
BYD2_k127_5747116_6	1313172.YM304_34610	9.178e-22	104.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
BYD2_k127_5747116_2	1944.JOAZ01000017_gene3649	1.616e-58	213.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4187I@629295|Streptomyces griseus group	201174|Actinobacteria	K	Sigma-70 region 3	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_5747116_5	1313172.YM304_32450	2.98e-32	135.0	COG1285@1|root,COG1285@2|Bacteria,2GJF0@201174|Actinobacteria,4CP2B@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
BYD2_k127_5747116_8	28444.JODQ01000002_gene4644	7.375e-10	65.0	COG1366@1|root,COG2172@1|root,COG1366@2|Bacteria,COG2172@2|Bacteria,2GTGW@201174|Actinobacteria,4EKE6@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
BYD2_k127_5747116_9	356851.JOAN01000017_gene5919	2.99e-08	60.0	COG2172@1|root,COG2172@2|Bacteria,2IFG9@201174|Actinobacteria,4DDYW@85008|Micromonosporales	201174|Actinobacteria	T	anti-sigma regulatory factor	rsbW	GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036094,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
BYD2_k127_5747116_4	287986.DV20_13830	9.481e-42	171.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4DYMB@85010|Pseudonocardiales	201174|Actinobacteria	K	RNA polymerase sigma factor, sigma-70 family	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_5747116_10	391037.Sare_2770	1.624e-06	58.0	COG2823@1|root,COG2823@2|Bacteria,2IS5M@201174|Actinobacteria,4DF8P@85008|Micromonosporales	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
BYD2_k127_5753142_8	103733.JNYO01000043_gene5945	7.65e-111	395.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria,4DY9X@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_5753142_2	1463825.JNXC01000006_gene2140	6.853e-269	842.0	COG5276@1|root,COG5276@2|Bacteria,2IBU7@201174|Actinobacteria,4EBUX@85010|Pseudonocardiales	201174|Actinobacteria	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD,PA
BYD2_k127_5753142_5	526225.Gobs_0181	1.432e-149	516.0	2DBC4@1|root,2Z8BS@2|Bacteria,2GYBF@201174|Actinobacteria,4ERMM@85013|Frankiales	201174|Actinobacteria	S	Responsible for the hydrolysis of barbituric acid (2,4,6-trihydroxy-1,3-pyrimidine), an intermediate in the oxidative catabolism of pyrimidines. Catalyzes the hydrolytic opening of the pyrimidine ring of barbituric acid to yield ureidomalonic acid	bar	-	3.5.2.1,3.5.2.15	ko:K03383,ko:K19794	ko00240,ko00791,ko01100,ko01120,map00240,map00791,map01100,map01120	-	R02139,R05561,R10777	RC00632,RC00680,RC01423,RC03058	ko00000,ko00001,ko01000	-	-	-	Amido_AtzD_TrzD
BYD2_k127_5753142_10	309801.trd_0571	2.843e-89	305.0	COG0549@1|root,COG0549@2|Bacteria,2G6C7@200795|Chloroflexi,27YXS@189775|Thermomicrobia	189775|Thermomicrobia	E	Amino acid kinase family	-	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
BYD2_k127_5753142_14	561175.KB894098_gene5448	1.021e-18	101.0	2EIHP@1|root,33C91@2|Bacteria,2ICMY@201174|Actinobacteria,4EH8I@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF2877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2877
BYD2_k127_5753142_3	28444.JODQ01000007_gene5527	5.351e-262	855.0	COG0074@1|root,COG0074@2|Bacteria,2GMFI@201174|Actinobacteria,4EFIV@85012|Streptosporangiales	201174|Actinobacteria	C	Protein of unknown function (DUF1116)	-	-	-	-	-	-	-	-	-	-	-	-	CoA_binding,DUF1116,Ligase_CoA
BYD2_k127_5753142_12	1123320.KB889640_gene4456	1.789e-68	263.0	COG1319@1|root,COG1319@2|Bacteria,2GP37@201174|Actinobacteria	201174|Actinobacteria	C	Molybdopterin dehydrogenase	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
BYD2_k127_5753142_11	2002.JOEQ01000014_gene5241	4.782e-73	251.0	COG2080@1|root,COG2080@2|Bacteria,2GMYH@201174|Actinobacteria,4EIUI@85012|Streptosporangiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	-	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
BYD2_k127_5753142_0	1394178.AWOO02000032_gene4938	0.0	1140.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4EGSV@85012|Streptosporangiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
BYD2_k127_5753142_9	479433.Caci_1875	2.603e-102	349.0	COG0388@1|root,COG0388@2|Bacteria,2GKRJ@201174|Actinobacteria	201174|Actinobacteria	S	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
BYD2_k127_5753142_4	1394178.AWOO02000032_gene4934	3.732e-257	827.0	COG0145@1|root,COG0145@2|Bacteria,2GIYE@201174|Actinobacteria,4EHQ4@85012|Streptosporangiales	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase N-terminal region	hyuA	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A
BYD2_k127_5753142_1	1123320.KB889640_gene4474	3.326e-303	955.0	COG0146@1|root,COG0146@2|Bacteria,2HWA8@201174|Actinobacteria	201174|Actinobacteria	EQ	PFAM Hydantoinase B oxoprolinase	hyuB	-	3.5.2.14	ko:K01474	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydantoinase_B
BYD2_k127_5753142_6	1380390.JIAT01000012_gene3163	6.896e-144	476.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CRJZ@84995|Rubrobacteria	84995|Rubrobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K12429	-	-	-	-	ko00000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_5753142_13	1280954.HPO_10827	6.328e-36	144.0	COG1309@1|root,COG1309@2|Bacteria,1N981@1224|Proteobacteria,2UIHZ@28211|Alphaproteobacteria,440DI@69657|Hyphomonadaceae	28211|Alphaproteobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_5753142_7	1123024.AUII01000015_gene3750	2.868e-136	448.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DXC9@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
BYD2_k127_5783261_0	1278073.MYSTI_01384	5.756e-20	98.0	COG0317@1|root,COG0317@2|Bacteria,1N2BZ@1224|Proteobacteria,430HK@68525|delta/epsilon subdivisions,2WVNF@28221|Deltaproteobacteria	28221|Deltaproteobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD_4
BYD2_k127_5783261_1	1463879.JOHP01000008_gene368	1.041e-19	96.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GPUP@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
BYD2_k127_5783261_2	309801.trd_0602	1.591e-09	65.0	COG4454@1|root,COG4454@2|Bacteria	2|Bacteria	-	-	copC	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,SoxE
BYD2_k127_5788845_2	1229780.BN381_10313	5.285e-212	669.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,3UWE5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC transporter	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
BYD2_k127_5788845_5	1828.JOKB01000053_gene4929	1.34e-77	273.0	COG0745@1|root,COG1587@1|root,COG0745@2|Bacteria,COG1587@2|Bacteria,2GKMM@201174|Actinobacteria,4FVJ7@85025|Nocardiaceae	201174|Actinobacteria	HKT	Uroporphyrinogen-III synthase HemD	hemD	-	4.2.1.75	ko:K01719	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R03165	RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Trans_reg_C
BYD2_k127_5788845_3	1173025.GEI7407_0754	1.06e-147	484.0	COG2223@1|root,COG2223@2|Bacteria,1G0NY@1117|Cyanobacteria,1H8IA@1150|Oscillatoriales	1117|Cyanobacteria	P	PFAM Major Facilitator Superfamily	nrtP	GO:0003674,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015112,GO:0015113,GO:0015318,GO:0015698,GO:0015706,GO:0015707,GO:0022857,GO:0034220,GO:0051179,GO:0051234,GO:0055085,GO:0071705,GO:0098656,GO:1902025	-	ko:K02575	ko00910,map00910	M00615	-	-	ko00000,ko00001,ko00002,ko02000	2.A.1.8	-	-	MFS_1
BYD2_k127_5788845_0	326424.FRAAL1355	1.352e-310	1004.0	COG1251@1|root,COG1251@2|Bacteria,2GJ3U@201174|Actinobacteria,4ERHE@85013|Frankiales	201174|Actinobacteria	C	BFD domain protein 2Fe-2S -binding domain protein	nirB	-	1.7.1.15	ko:K00362	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_BFD,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2
BYD2_k127_5788845_7	1123024.AUII01000005_gene2275	2.477e-28	132.0	COG2146@1|root,COG2146@2|Bacteria,2IQM4@201174|Actinobacteria,4E5QF@85010|Pseudonocardiales	201174|Actinobacteria	P	nitrite reductase	nirD	-	1.7.1.15	ko:K00363	ko00910,ko01120,map00910,map01120	M00530	R00787	RC00176	ko00000,ko00001,ko00002,ko01000	-	-	-	Rieske_2
BYD2_k127_5788845_4	234267.Acid_0182	8.347e-106	361.0	COG0437@1|root,COG3302@1|root,COG0437@2|Bacteria,COG3302@2|Bacteria,3Y5RE@57723|Acidobacteria	57723|Acidobacteria	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	DmsC,Fer4_11
BYD2_k127_5788845_1	234267.Acid_0183	8.838e-263	831.0	COG0243@1|root,COG0243@2|Bacteria,3Y2HB@57723|Acidobacteria	57723|Acidobacteria	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	ko:K00372	ko00910,ko01120,map00910,map01120	M00531	R00798,R01106	RC02812	ko00000,ko00001,ko00002,ko01000	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
BYD2_k127_5788845_6	711393.AYRX01000083_gene4764	2.416e-71	250.0	2B37N@1|root,31VVP@2|Bacteria,2GWAN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2
BYD2_k127_5788845_8	68194.JNXR01000007_gene3822	1.173e-12	72.0	COG0508@1|root,COG0567@1|root,COG0508@2|Bacteria,COG0567@2|Bacteria,2GIU6@201174|Actinobacteria	201174|Actinobacteria	C	Dehydrogenase E1 component	kgd	-	1.2.4.2	ko:K00164	ko00020,ko00310,ko00380,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00310,map00380,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032	R00621,R01933,R01940,R03316,R08549	RC00004,RC00027,RC00627,RC02743,RC02833,RC02883	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,2-oxogl_dehyd_N,E1_dh,OxoGdeHyase_C,Transket_pyr
BYD2_k127_5791819_4	285535.JOEY01000035_gene3715	0.0003596	49.0	COG0477@1|root,COG0477@2|Bacteria,2H6BY@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_5791819_1	656024.FsymDg_4333	1.579e-68	244.0	COG3315@1|root,COG3315@2|Bacteria,2GMBA@201174|Actinobacteria,4ESC1@85013|Frankiales	201174|Actinobacteria	Q	S-adenosyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_19
BYD2_k127_5791819_0	1229780.BN381_40074	1.852e-246	773.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,3UX1Q@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Carboxyl transferase domain	yngE	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
BYD2_k127_5791819_2	1229780.BN381_40073	1.985e-67	238.0	COG2208@1|root,COG2208@2|Bacteria,2IHH3@201174|Actinobacteria	201174|Actinobacteria	KT	stage II sporulation	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
BYD2_k127_5800057_2	326424.FRAAL0708	4.475e-26	110.0	COG2267@1|root,COG2267@2|Bacteria	2|Bacteria	I	carboxylic ester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
BYD2_k127_5800057_1	525909.Afer_0762	1.78e-69	248.0	COG0740@1|root,COG0740@2|Bacteria,2GKNK@201174|Actinobacteria,4CMUY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
BYD2_k127_5800057_3	1380390.JIAT01000014_gene6142	1.582e-25	115.0	COG0640@1|root,COG0640@2|Bacteria,2GS7J@201174|Actinobacteria,4CT34@84995|Rubrobacteria	84995|Rubrobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_5800057_0	477641.MODMU_1322	2.555e-87	299.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4EU4W@85013|Frankiales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
BYD2_k127_586228_7	561175.KB894096_gene526	1.831e-75	254.0	COG0447@1|root,COG0447@2|Bacteria,2GK5G@201174|Actinobacteria,4EI6I@85012|Streptosporangiales	201174|Actinobacteria	H	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)	menB	GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0008150,GO:0008152,GO:0008935,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016043,GO:0016829,GO:0016830,GO:0016833,GO:0022607,GO:0034214,GO:0042180,GO:0042181,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0051186,GO:0051188,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:1901576,GO:1901661,GO:1901663	4.1.3.36	ko:K01661	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R07263	RC01923	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_586228_10	222534.KB893717_gene2176	3.546e-37	158.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,Cytochrom_C
BYD2_k127_586228_11	512565.AMIS_310	8.669e-31	126.0	COG1846@1|root,COG1846@2|Bacteria,2IPBX@201174|Actinobacteria,4DCPX@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
BYD2_k127_586228_8	390989.JOEG01000003_gene4626	6.094e-71	258.0	COG0035@1|root,COG0035@2|Bacteria,2GPJE@201174|Actinobacteria,4DBBE@85008|Micromonosporales	201174|Actinobacteria	F	uracil phosphoribosyltransferase	upp	GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
BYD2_k127_586228_1	561175.KB894093_gene3201	6.672e-180	583.0	COG1109@1|root,COG1109@2|Bacteria,2GJ3Q@201174|Actinobacteria,4EHG1@85012|Streptosporangiales	201174|Actinobacteria	G	Phosphoglucomutase/phosphomannomutase, C-terminal domain	pmmB	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
BYD2_k127_586228_12	1304865.JAGF01000001_gene10	1.772e-20	99.0	COG1848@1|root,COG1848@2|Bacteria,2GRA5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
BYD2_k127_586228_13	1123023.JIAI01000008_gene1496	2.45e-16	82.0	COG4118@1|root,COG4118@2|Bacteria,2GZW9@201174|Actinobacteria	201174|Actinobacteria	D	Antitoxin component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
BYD2_k127_586228_6	1123023.JIAI01000010_gene8500	6.411e-101	335.0	COG0005@1|root,COG0005@2|Bacteria,2GKEI@201174|Actinobacteria,4DXJF@85010|Pseudonocardiales	201174|Actinobacteria	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	punA	GO:0003674,GO:0003824,GO:0004731,GO:0006139,GO:0006152,GO:0006161,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009116,GO:0009120,GO:0009164,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0019439,GO:0034641,GO:0034655,GO:0034656,GO:0042278,GO:0042453,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046121,GO:0046122,GO:0046124,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901657,GO:1901658	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
BYD2_k127_586228_5	1122933.JNIY01000003_gene854	1.085e-106	357.0	COG1744@1|root,COG1744@2|Bacteria,2GMFS@201174|Actinobacteria,4F0NG@85016|Cellulomonadaceae	201174|Actinobacteria	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
BYD2_k127_586228_0	926569.ANT_27890	6.951e-183	585.0	COG3845@1|root,COG3845@2|Bacteria,2G625@200795|Chloroflexi	200795|Chloroflexi	S	PFAM ABC transporter related	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
BYD2_k127_586228_4	1120950.KB892760_gene5784	2.386e-110	372.0	COG4603@1|root,COG4603@2|Bacteria,2GKAZ@201174|Actinobacteria,4DNPP@85009|Propionibacteriales	201174|Actinobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
BYD2_k127_586228_3	1469613.JT55_05230	4.353e-111	373.0	COG1079@1|root,COG1079@2|Bacteria,1MVDQ@1224|Proteobacteria,2TSTD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
BYD2_k127_586228_9	356851.JOAN01000001_gene3738	3.146e-48	175.0	COG0295@1|root,COG0295@2|Bacteria,2IHP7@201174|Actinobacteria,4DBEW@85008|Micromonosporales	201174|Actinobacteria	F	cytidine deaminase	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
BYD2_k127_586228_2	471852.Tcur_4189	1.899e-172	550.0	COG0213@1|root,COG0213@2|Bacteria,2GJH5@201174|Actinobacteria,4EG7W@85012|Streptosporangiales	201174|Actinobacteria	F	Pyrimidine nucleoside phosphorylase C-terminal domain	deoA	GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464	2.4.2.2,2.4.2.4	ko:K00756,ko:K00758	ko00240,ko00983,ko01100,ko05219,map00240,map00983,map01100,map05219	-	R01570,R01876,R02296,R02484,R08222,R08230	RC00063	ko00000,ko00001,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3,PYNP_C
BYD2_k127_58633_3	479433.Caci_1652	6.043e-17	89.0	COG2001@1|root,COG2001@2|Bacteria,2IHUB@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the MraZ family	mraZ	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0040007,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
BYD2_k127_58633_1	935866.JAER01000024_gene3108	2.478e-43	173.0	COG0095@1|root,COG0095@2|Bacteria,2GTPJ@201174|Actinobacteria	201174|Actinobacteria	H	Lipoate-protein ligase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_58633_0	1313172.YM304_19370	2.417e-55	199.0	COG1403@1|root,COG1403@2|Bacteria,2GN1W@201174|Actinobacteria,4CN5M@84992|Acidimicrobiia	84992|Acidimicrobiia	L	HNH endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	HNH_5
BYD2_k127_58633_4	1229780.BN381_140020	0.0001416	44.0	COG1940@1|root,COG1940@2|Bacteria,2GJCQ@201174|Actinobacteria,3UWRA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
BYD2_k127_5908859_2	1229780.BN381_90069	1.17e-45	181.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
BYD2_k127_5908859_1	1229780.BN381_60038	3.231e-61	229.0	COG0142@1|root,COG0142@2|Bacteria,2GMB4@201174|Actinobacteria,3UWQP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Polyprenyl synthetase	-	-	2.5.1.30,2.5.1.90	ko:K00805,ko:K02523	ko00900,ko01110,map00900,map01110	-	R09247,R09248	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	polyprenyl_synt
BYD2_k127_5908859_4	436229.JOEH01000004_gene413	1.161e-28	133.0	COG1309@1|root,COG1309@2|Bacteria,2GMZ1@201174|Actinobacteria,2NH3U@228398|Streptacidiphilus	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_5908859_3	1348663.KCH_16240	3.75e-34	136.0	2CRBS@1|root,32SNS@2|Bacteria,2IQS0@201174|Actinobacteria	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_5908859_0	1122138.AQUZ01000008_gene3758	5.949e-263	829.0	COG3590@1|root,COG3590@2|Bacteria,2GNJY@201174|Actinobacteria,4DQ4I@85009|Propionibacteriales	201174|Actinobacteria	O	Peptidase family M13	pepO	-	3.4.24.11,3.4.24.71	ko:K01389,ko:K01415,ko:K07386	ko04614,ko04640,ko04974,ko05010,map04614,map04640,map04974,map05010	-	-	-	ko00000,ko00001,ko01000,ko01002,ko04090,ko04147	-	-	-	Peptidase_M13,Peptidase_M13_N
BYD2_k127_5926986_1	1123322.KB904635_gene2634	6.707e-92	308.0	COG0596@1|root,COG0596@2|Bacteria,2HEMJ@201174|Actinobacteria	201174|Actinobacteria	E	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_5926986_0	1123322.KB904635_gene2633	2.638e-124	418.0	COG2378@1|root,COG2378@2|Bacteria,2GKTS@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
BYD2_k127_5931250_17	1229780.BN381_80340	6.479e-48	176.0	COG0513@1|root,COG0513@2|Bacteria,2GIUR@201174|Actinobacteria,3UW8N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,Helicase_C
BYD2_k127_5931250_7	1120950.KB892708_gene4333	1.434e-83	280.0	COG0494@1|root,COG0494@2|Bacteria,2GKUV@201174|Actinobacteria,4DRZ4@85009|Propionibacteriales	201174|Actinobacteria	L	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_5931250_18	408672.NBCG_02339	1.042e-46	178.0	COG0454@1|root,COG0456@2|Bacteria,2IMKI@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
BYD2_k127_5931250_11	935866.JAER01000052_gene2866	1.745e-68	257.0	COG0827@1|root,COG0827@2|Bacteria,2HZT5@201174|Actinobacteria,4DSQJ@85009|Propionibacteriales	201174|Actinobacteria	L	N-6 DNA Methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_Mtase
BYD2_k127_5931250_1	1313172.YM304_23840	3.682e-152	520.0	COG2021@1|root,COG2021@2|Bacteria,2GKNJ@201174|Actinobacteria,4CNHB@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metX	-	2.3.1.31	ko:K00641	ko00270,ko01100,ko01130,map00270,map01100,map01130	-	R01776	RC00004,RC00041	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_1
BYD2_k127_5931250_2	1229780.BN381_80350	1.22e-124	413.0	COG0626@1|root,COG0626@2|Bacteria,2GJ5S@201174|Actinobacteria,3UX88@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	megL	-	2.5.1.48,2.5.1.49,4.4.1.11	ko:K01739,ko:K01740,ko:K01761	ko00270,ko00450,ko00920,ko01100,ko01110,ko01130,ko01230,map00270,map00450,map00920,map01100,map01110,map01130,map01230	M00017	R00654,R00999,R01287,R01288,R02508,R03217,R03260,R04770,R04859,R04944,R04945,R04946	RC00020,RC00056,RC00069,RC00196,RC00348,RC00420,RC01209,RC01210,RC02821,RC02848,RC02866	ko00000,ko00001,ko00002,ko01000	-	-	-	Cys_Met_Meta_PP
BYD2_k127_5931250_15	43989.cce_3312	2.53e-55	207.0	2DBB1@1|root,2Z854@2|Bacteria,1G05N@1117|Cyanobacteria,3KHER@43988|Cyanothece	1117|Cyanobacteria	S	Domain of Unknown Function (DUF1206)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1206
BYD2_k127_5931250_20	1150864.MILUP08_45283	5.331e-27	115.0	COG3324@1|root,COG3324@2|Bacteria,2GVZ9@201174|Actinobacteria,4DGJV@85008|Micromonosporales	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
BYD2_k127_5931250_13	543632.JOJL01000050_gene7358	5.699e-63	226.0	COG2378@1|root,COG2378@2|Bacteria,2H5IT@201174|Actinobacteria,4DDWU@85008|Micromonosporales	201174|Actinobacteria	K	WYL domain	-	-	-	ko:K13572	-	-	-	-	ko00000,ko03051	-	-	-	HTH_11,WYL
BYD2_k127_5931250_14	1229780.BN381_80351	1.151e-61	224.0	COG0266@1|root,COG0266@2|Bacteria,2H39J@201174|Actinobacteria	201174|Actinobacteria	L	formamidopyrimidine-DNA glycosylase	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
BYD2_k127_5931250_21	1121877.JQKF01000027_gene2453	3.835e-19	89.0	2ANAN@1|root,31D8Y@2|Bacteria,2HGVW@201174|Actinobacteria,4CNX0@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_5931250_12	1123023.JIAI01000031_gene4106	1.628e-65	229.0	COG3145@1|root,COG3145@2|Bacteria,2GNBD@201174|Actinobacteria,4E0FZ@85010|Pseudonocardiales	201174|Actinobacteria	L	2OG-Fe(II) oxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2OG-FeII_Oxy_2
BYD2_k127_5931250_10	1122223.KB890696_gene74	1.58e-69	247.0	COG0834@1|root,COG0834@2|Bacteria,1WMI9@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	ET	Bacterial periplasmic substrate-binding proteins	-	-	-	ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
BYD2_k127_5931250_9	266779.Meso_3148	3.615e-77	271.0	COG0765@1|root,COG0765@2|Bacteria,1N786@1224|Proteobacteria,2U10S@28211|Alphaproteobacteria,43ITH@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	E	Polar amino acid ABC transporter	-	-	-	ko:K02029	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1
BYD2_k127_5931250_3	526227.Mesil_2806	3.099e-111	366.0	COG1126@1|root,COG1126@2|Bacteria,1WI0Q@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	E	ABC-type polar amino acid transport system ATPase component	-	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
BYD2_k127_5931250_6	1380391.JIAS01000018_gene887	3.8e-96	325.0	COG4638@1|root,COG4638@2|Bacteria,1MWXW@1224|Proteobacteria,2U071@28211|Alphaproteobacteria,2JZMF@204441|Rhodospirillales	204441|Rhodospirillales	P	Ring hydroxylating alpha subunit (catalytic domain)	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
BYD2_k127_5931250_0	1449049.JONW01000006_gene3185	2.066e-160	517.0	COG1520@1|root,COG1520@2|Bacteria,1Q8U9@1224|Proteobacteria,2UYME@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	PQQ-like domain	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2
BYD2_k127_5931250_8	1122611.KB903969_gene2414	2.777e-82	279.0	COG1309@1|root,COG1309@2|Bacteria,2I1Q4@201174|Actinobacteria,4EQ0G@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_5931250_4	1206737.BAGF01000072_gene4606	9.496e-110	370.0	COG1680@1|root,COG1680@2|Bacteria,2GK3A@201174|Actinobacteria,4FWDI@85025|Nocardiaceae	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_5931250_16	1449069.JMLO01000034_gene128	3.946e-51	205.0	COG5361@1|root,COG5361@2|Bacteria,2GRDZ@201174|Actinobacteria,4FWN7@85025|Nocardiaceae	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
BYD2_k127_5931250_5	1122611.KB903969_gene2412	4.225e-101	362.0	COG5361@1|root,COG5361@2|Bacteria,2HR5D@201174|Actinobacteria,4EPSR@85012|Streptosporangiales	201174|Actinobacteria	S	Protein of unknown function (DUF1254)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214,DUF1254
BYD2_k127_5931250_19	1122194.AUHU01000004_gene1502	2.499e-39	154.0	COG1670@1|root,COG1670@2|Bacteria,1RB1I@1224|Proteobacteria,1S7ZE@1236|Gammaproteobacteria,467KT@72275|Alteromonadaceae	1236|Gammaproteobacteria	J	Domain of unknown function (DUF4202)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4202
BYD2_k127_5992327_2	1449069.JMLO01000036_gene2614	5.17e-107	349.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4FUHJ@85025|Nocardiaceae	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
BYD2_k127_5992327_0	1278073.MYSTI_04482	1.675e-150	481.0	COG0175@1|root,COG0175@2|Bacteria,1MUCZ@1224|Proteobacteria,42NYE@68525|delta/epsilon subdivisions,2WK6Q@28221|Deltaproteobacteria,2YTSR@29|Myxococcales	28221|Deltaproteobacteria	H	Phosphoadenosine phosphosulfate reductase family	cysD	-	2.7.7.4	ko:K00957	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00529,R04929	RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	PAPS_reduct
BYD2_k127_5992327_3	1206720.BAFQ01000293_gene6399	1.423e-92	310.0	COG1218@1|root,COG1218@2|Bacteria,2GMW7@201174|Actinobacteria,4FYAJ@85025|Nocardiaceae	201174|Actinobacteria	P	Inositol monophosphatase family	cysQ	-	3.1.3.7	ko:K01082	ko00920,ko01100,ko01120,ko01130,map00920,map01100,map01120,map01130	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03016	-	-	-	Inositol_P
BYD2_k127_5992327_1	402881.Plav_2677	1.542e-109	361.0	COG5285@1|root,COG5285@2|Bacteria,1QRDD@1224|Proteobacteria,2U0EC@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
BYD2_k127_5992327_4	1229780.BN381_360022	3.257e-87	302.0	COG1680@1|root,COG1680@2|Bacteria,2HEWU@201174|Actinobacteria,3UXIA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_5992327_5	502025.Hoch_5381	1.233e-39	154.0	COG4221@1|root,COG4221@2|Bacteria,1QVTE@1224|Proteobacteria	1224|Proteobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	yueD	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_6011668_1	861299.J421_1359	5.41e-30	136.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
BYD2_k127_6011668_0	861299.J421_1359	1.499e-30	139.0	COG0823@1|root,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	tolB	-	-	ko:K03641	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	PD40
BYD2_k127_6019976_0	1306174.JODP01000007_gene2384	3.377e-92	316.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,2GNP7@201174|Actinobacteria	201174|Actinobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD3	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA,Carboxyl_trans,MdcE
BYD2_k127_6019976_1	590998.Celf_2464	0.0009931	51.0	COG1652@1|root,COG1652@2|Bacteria,2GQMU@201174|Actinobacteria,4F2PE@85016|Cellulomonadaceae	201174|Actinobacteria	S	PFAM Peptidoglycan-binding lysin domain	-	-	-	-	-	-	-	-	-	-	-	-	LysM
BYD2_k127_6022437_0	1032480.MLP_14610	2.71e-134	446.0	COG0488@1|root,COG0488@2|Bacteria,2GKQ4@201174|Actinobacteria,4DPPB@85009|Propionibacteriales	201174|Actinobacteria	S	ABC transporter	ybiT	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn,DLIC
BYD2_k127_6022437_5	1394178.AWOO02000005_gene3533	4.652e-24	110.0	COG1309@1|root,COG1309@2|Bacteria,2GNGT@201174|Actinobacteria,4EJ5E@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_6022437_6	298655.KI912266_gene5512	3.645e-13	81.0	COG2227@1|root,COG2227@2|Bacteria,2GNRH@201174|Actinobacteria,4ETID@85013|Frankiales	201174|Actinobacteria	H	PFAM methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
BYD2_k127_6022437_1	1313172.YM304_02680	8.198e-94	326.0	COG0258@1|root,COG0258@2|Bacteria,2H2A3@201174|Actinobacteria	201174|Actinobacteria	L	5'-3' exonuclease, C-terminal SAM fold	-	-	-	-	-	-	-	-	-	-	-	-	5_3_exonuc,5_3_exonuc_N
BYD2_k127_6022437_7	1386089.N865_21240	6.869e-08	65.0	2DU40@1|root,33NV5@2|Bacteria,2GTWE@201174|Actinobacteria	201174|Actinobacteria	S	Predicted membrane protein (DUF2157)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2157
BYD2_k127_6022437_2	298653.Franean1_5199	1.715e-61	237.0	COG1595@1|root,COG1595@2|Bacteria,2GKBH@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_6022437_3	1254432.SCE1572_45305	2.251e-60	226.0	COG1233@1|root,COG1233@2|Bacteria,1QXT4@1224|Proteobacteria,43C5J@68525|delta/epsilon subdivisions,2X7FU@28221|Deltaproteobacteria,2YUIG@29|Myxococcales	28221|Deltaproteobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
BYD2_k127_6022437_4	1313172.YM304_00280	1.984e-56	200.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_6031370_2	710421.Mycch_3390	1.705e-38	153.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,2354F@1762|Mycobacteriaceae	201174|Actinobacteria	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_6031370_1	369723.Strop_3108	8.085e-77	267.0	COG0596@1|root,COG0596@2|Bacteria,2I32Y@201174|Actinobacteria,4DDH9@85008|Micromonosporales	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_6031370_0	47763.JNZA01000001_gene4191	1.251e-82	281.0	COG0412@1|root,COG0412@2|Bacteria,2GTZG@201174|Actinobacteria	201174|Actinobacteria	Q	dienelactone hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	DLH
BYD2_k127_6031370_3	1114959.SZMC14600_02782	4.998e-11	64.0	COG0737@1|root,COG0737@2|Bacteria,2I0BA@201174|Actinobacteria,4E0SA@85010|Pseudonocardiales	201174|Actinobacteria	F	Belongs to the 5'-nucleotidase family	-	-	-	-	-	-	-	-	-	-	-	-	5_nucleotid_C
BYD2_k127_6034831_5	1146883.BLASA_1707	5.97e-20	93.0	COG0596@1|root,COG0596@2|Bacteria,2I2QI@201174|Actinobacteria	201174|Actinobacteria	S	hydrolases or acyltransferases alpha beta hydrolase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_6034831_0	1283283.ATXA01000008_gene3194	2.36e-213	694.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria	201174|Actinobacteria	T	integral membrane protein	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
BYD2_k127_6034831_6	1283287.KB822584_gene1326	1.083e-15	85.0	2DY9S@1|root,348TG@2|Bacteria,2H8I0@201174|Actinobacteria	201174|Actinobacteria	S	YGGT family	-	-	-	-	-	-	-	-	-	-	-	-	YGGT
BYD2_k127_6034831_1	1380356.JNIK01000015_gene2351	7.679e-190	616.0	COG0531@1|root,COG0531@2|Bacteria,2IDWU@201174|Actinobacteria	201174|Actinobacteria	E	Amino acid permease	potE	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
BYD2_k127_6034831_3	1121946.AUAX01000010_gene3768	2.039e-57	209.0	COG1288@1|root,COG1288@2|Bacteria,2HK5U@201174|Actinobacteria	201174|Actinobacteria	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
BYD2_k127_6034831_2	1097668.BYI23_C008170	6.692e-63	232.0	COG1053@1|root,COG1053@2|Bacteria,1QWW9@1224|Proteobacteria,2VPPG@28216|Betaproteobacteria,1KGZ2@119060|Burkholderiaceae	28216|Betaproteobacteria	C	Thi4 family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
BYD2_k127_6034831_4	1229780.BN381_60079	7.569e-41	162.0	COG4188@1|root,COG4188@2|Bacteria,2I9HM@201174|Actinobacteria	201174|Actinobacteria	O	collagen metabolic process	-	-	-	-	-	-	-	-	-	-	-	-	Chlorophyllase2,PAF-AH_p_II
BYD2_k127_6055859_3	202952.BBLI01000003_gene293	1.428e-09	59.0	2DRA2@1|root,33AVQ@2|Bacteria,1NKZA@1224|Proteobacteria,1SH2Z@1236|Gammaproteobacteria,3NQGN@468|Moraxellaceae	1236|Gammaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6055859_0	1313172.YM304_05100	2.396e-209	687.0	COG1615@1|root,COG1615@2|Bacteria,2GMP3@201174|Actinobacteria,4CMW1@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Uncharacterised protein family (UPF0182)	-	-	-	ko:K09118	-	-	-	-	ko00000	-	-	-	UPF0182
BYD2_k127_6055859_2	1313172.YM304_05090	2.935e-47	196.0	COG3599@1|root,COG3599@2|Bacteria	2|Bacteria	D	regulation of cell shape	-	-	-	ko:K04074	-	-	-	-	ko00000,ko03036	-	-	-	DivIVA
BYD2_k127_6055859_1	1229780.BN381_130112	4.374e-54	210.0	COG3480@1|root,COG3480@2|Bacteria,2GJDD@201174|Actinobacteria,3UWKY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Domain present in PSD-95, Dlg, and ZO-1/2.	ylbL	-	-	ko:K07177	ko02024,map02024	-	-	-	ko00000,ko00001,ko01002	-	-	-	Lon_C,PDZ_2
BYD2_k127_6063801_14	1120960.ATXG01000020_gene3317	7.78e-06	57.0	2EH2S@1|root,33AUR@2|Bacteria,2GTMR@201174|Actinobacteria,4FSCK@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6063801_9	1193128.A200_07754	4.795e-21	109.0	COG0433@1|root,COG0433@2|Bacteria,2IGPW@201174|Actinobacteria	201174|Actinobacteria	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
BYD2_k127_6063801_10	395493.BegalDRAFT_2073	1.363e-17	98.0	COG0587@1|root,COG0587@2|Bacteria,1MUIF@1224|Proteobacteria,1RP0K@1236|Gammaproteobacteria,4602D@72273|Thiotrichales	72273|Thiotrichales	L	DNA polymerase III alpha subunit	dnaE	-	2.7.7.7	ko:K02337	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
BYD2_k127_6063801_15	1246459.KB898354_gene4644	5.125e-05	57.0	COG0489@1|root,COG3206@1|root,COG0489@2|Bacteria,COG3206@2|Bacteria,1MVI9@1224|Proteobacteria,2TT1Y@28211|Alphaproteobacteria,4BCGK@82115|Rhizobiaceae	28211|Alphaproteobacteria	D	G-rich domain on putative tyrosine kinase	-	-	-	ko:K16554	ko05111,map05111	-	-	-	ko00000,ko00001,ko02000	8.A.3.1	-	-	AAA_31,CbiA,GNVR,Wzz
BYD2_k127_6063801_1	1206733.BAGC01000035_gene3681	3.873e-110	368.0	COG5031@1|root,COG5031@2|Bacteria,2HJ7V@201174|Actinobacteria,4G5PP@85025|Nocardiaceae	201174|Actinobacteria	H	ubiquinone biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6063801_11	1280390.CBQR020000010_gene277	1.768e-09	68.0	COG1525@1|root,COG1525@2|Bacteria,1V3MZ@1239|Firmicutes,4HHPS@91061|Bacilli,26XV4@186822|Paenibacillaceae	91061|Bacilli	L	Staphylococcal nuclease homologues	nucH	-	3.1.31.1	ko:K01174	-	-	-	-	ko00000,ko01000	-	-	-	SNase
BYD2_k127_6063801_12	1122138.AQUZ01000006_gene1278	4.507e-09	68.0	COG3428@1|root,COG3428@2|Bacteria,2IA1C@201174|Actinobacteria,4DR83@85009|Propionibacteriales	201174|Actinobacteria	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
BYD2_k127_6063801_0	1206739.BAGJ01000180_gene6621	1.256e-205	647.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria,4FW5B@85025|Nocardiaceae	201174|Actinobacteria	S	Nitronate monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
BYD2_k127_6063801_13	1123320.KB889671_gene3425	4.326e-07	61.0	COG1309@1|root,COG1309@2|Bacteria,2IDJT@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_6063801_4	469383.Cwoe_3783	3.071e-63	226.0	COG2411@1|root,COG2411@2|Bacteria,2HRSA@201174|Actinobacteria,4CTVC@84995|Rubrobacteria	84995|Rubrobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6063801_2	1229780.BN381_100013	2.202e-106	351.0	COG0491@1|root,COG0491@2|Bacteria,2GJU0@201174|Actinobacteria,3UXE8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	3.1.2.6	ko:K01069	ko00620,map00620	-	R01736	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
BYD2_k127_6063801_7	561175.KB894097_gene219	4.368e-28	126.0	COG3467@1|root,COG3467@2|Bacteria,2I5VH@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_6063801_8	649638.Trad_1270	8.928e-28	121.0	COG2148@1|root,COG2148@2|Bacteria,1WJRF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	M	Bacterial sugar transferase	-	-	2.7.8.40	ko:K21303	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	-	-	Bac_transf
BYD2_k127_6063801_6	1034769.KB910518_gene2773	1.708e-37	157.0	COG0031@1|root,COG0031@2|Bacteria,1V396@1239|Firmicutes,4HG3Q@91061|Bacilli,26SH0@186822|Paenibacillaceae	91061|Bacilli	E	Pyridoxal-phosphate dependent enzyme	-	-	2.5.1.140,6.2.1.30	ko:K01912,ko:K21949	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539,R11705	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,PALP
BYD2_k127_6063801_3	1120950.KB892707_gene4890	5.358e-67	243.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,4DN0T@85009|Propionibacteriales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227,6.3.2.8	ko:K01924,ko:K02563	ko00471,ko00550,ko01100,ko01502,ko04112,map00471,map00550,map01100,map01502,map04112	-	R03193,R05032,R05662	RC00005,RC00049,RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
BYD2_k127_6063801_5	926564.KI911765_gene4578	2.715e-50	185.0	COG0645@1|root,COG0645@2|Bacteria	2|Bacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18,AAA_33,CPT
BYD2_k127_6075756_26	1160137.KB907308_gene6583	1.429e-15	81.0	2DI8M@1|root,32UAP@2|Bacteria,2GR9W@201174|Actinobacteria,4G433@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_6075756_23	345341.KUTG_08970	5.22e-43	165.0	COG1846@1|root,COG1846@2|Bacteria,2IFW0@201174|Actinobacteria,4E5M3@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
BYD2_k127_6075756_2	68260.JOAY01000035_gene2528	1.248e-169	546.0	COG0477@1|root,COG0477@2|Bacteria,2ID82@201174|Actinobacteria	201174|Actinobacteria	EGP	Major facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_6075756_21	47763.JNZA01000023_gene2944	9.508e-50	179.0	COG0640@1|root,COG0640@2|Bacteria,2IQH9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_6075756_16	1343740.M271_16335	6.349e-73	255.0	COG3832@1|root,COG3832@2|Bacteria,2H75S@201174|Actinobacteria	201174|Actinobacteria	S	Activator of hsp90 atpase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_6075756_24	1313172.YM304_31100	2.879e-30	135.0	COG0739@1|root,COG0739@2|Bacteria	2|Bacteria	M	heme binding	-	-	-	ko:K21471,ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	LysM,Peptidase_M23
BYD2_k127_6075756_25	1205910.B005_2496	6.646e-29	125.0	COG1309@1|root,COG1309@2|Bacteria,2GP59@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_6075756_11	471852.Tcur_2477	2.373e-85	298.0	COG0346@1|root,COG0346@2|Bacteria,2HKRN@201174|Actinobacteria,4EJAM@85012|Streptosporangiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_6075756_18	471852.Tcur_1124	2.207e-64	228.0	COG0784@1|root,COG0784@2|Bacteria,2IFH8@201174|Actinobacteria,4ER7Q@85012|Streptosporangiales	201174|Actinobacteria	T	cheY-homologous receiver domain	rcp1	-	-	ko:K02485	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg
BYD2_k127_6075756_4	106370.Francci3_0291	7.436e-117	394.0	COG4251@1|root,COG5278@1|root,COG4251@2|Bacteria,COG5278@2|Bacteria,2GK25@201174|Actinobacteria,4EURC@85013|Frankiales	201174|Actinobacteria	T	CHASE3 domain	-	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HAMP,HATPase_c,HisKA
BYD2_k127_6075756_10	208444.JNYY01000004_gene2004	1.229e-94	324.0	COG0784@1|root,COG2208@1|root,COG0784@2|Bacteria,COG2208@2|Bacteria,2GNAF@201174|Actinobacteria,4DZCW@85010|Pseudonocardiales	201174|Actinobacteria	T	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,SpoIIE
BYD2_k127_6075756_22	1110697.NCAST_05_04430	3.144e-44	169.0	COG2197@1|root,COG2197@2|Bacteria,2GKBX@201174|Actinobacteria	201174|Actinobacteria	T	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_6075756_6	391037.Sare_4398	1.305e-111	393.0	COG1409@1|root,COG1409@2|Bacteria,2GP1M@201174|Actinobacteria,4DBV7@85008|Micromonosporales	201174|Actinobacteria	S	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
BYD2_k127_6075756_3	298655.KI912267_gene6654	2.443e-126	416.0	COG0282@1|root,COG0282@2|Bacteria,2GJAW@201174|Actinobacteria,4ERMI@85013|Frankiales	201174|Actinobacteria	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
BYD2_k127_6075756_0	1380390.JIAT01000010_gene3879	0.0	1267.0	COG3957@1|root,COG3957@2|Bacteria,2GN27@201174|Actinobacteria,4CSGY@84995|Rubrobacteria	84995|Rubrobacteria	G	D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase	-	-	4.1.2.22,4.1.2.9	ko:K01621	ko00030,ko00710,ko01100,ko01120,map00030,map00710,map01100,map01120	-	R00761,R01621	RC00032,RC00226	ko00000,ko00001,ko01000	-	-	-	XFP,XFP_C,XFP_N
BYD2_k127_6075756_7	561175.KB894094_gene1626	2.748e-111	398.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria,4EIEI@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
BYD2_k127_6075756_19	285514.JNWO01000005_gene2029	5.796e-58	214.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_6075756_13	426716.JOAJ01000011_gene6479	2.486e-83	297.0	COG3540@1|root,COG3540@2|Bacteria,2GJCI@201174|Actinobacteria,4FWDN@85025|Nocardiaceae	201174|Actinobacteria	P	alkaline phosphatase	phoD	-	3.1.3.1	ko:K01077,ko:K01113	ko00730,ko00790,ko01100,ko02020,map00730,map00790,map01100,map02020	M00126	R02135,R04620	RC00017	ko00000,ko00001,ko00002,ko00537,ko01000,ko04147	-	-	-	PhoD,PhoD_N
BYD2_k127_6075756_5	298654.FraEuI1c_1885	5.047e-115	404.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria	201174|Actinobacteria	P	alcohol dehydrogenase	-	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_6075756_14	222534.KB893716_gene1819	3.052e-81	276.0	COG0778@1|root,COG0778@2|Bacteria,2I94X@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_6075756_20	1299327.I546_6651	6.217e-55	218.0	COG5285@1|root,COG5285@2|Bacteria,2HSYC@201174|Actinobacteria,23EJ4@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Phytanoyl-CoA dioxygenase (PhyH)	-	-	-	-	-	-	-	-	-	-	-	-	PhyH
BYD2_k127_6075756_17	1157634.KB912975_gene552	2.071e-68	255.0	COG0693@1|root,COG0693@2|Bacteria,2H6FV@201174|Actinobacteria	201174|Actinobacteria	S	ThiJ PfpI	thiJ	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
BYD2_k127_6075756_9	1463900.JOIX01000011_gene3301	1.19e-100	342.0	COG4977@1|root,COG4977@2|Bacteria,2GM0M@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI,HTH_18
BYD2_k127_6075756_12	1229780.BN381_150092	7.89e-84	290.0	COG1215@1|root,COG1215@2|Bacteria,2GMKV@201174|Actinobacteria,3UXD7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferase family 2	gpgS	-	2.4.1.266	ko:K13693	-	-	-	-	ko00000,ko01000,ko01003	-	GT81	-	Glycos_transf_2
BYD2_k127_6075756_15	469383.Cwoe_3796	4.199e-78	279.0	COG0294@1|root,COG0294@2|Bacteria,2GJNI@201174|Actinobacteria,4CT4V@84995|Rubrobacteria	84995|Rubrobacteria	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
BYD2_k127_6075756_1	1894.JOER01000043_gene6596	2.19e-250	798.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria	201174|Actinobacteria	Q	ABC transporter (Permease)	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_6075756_8	469383.Cwoe_4858	1.045e-107	359.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4CPWA@84995|Rubrobacteria	84995|Rubrobacteria	V	PFAM ABC transporter related	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_6075756_27	743718.Isova_0631	1.263e-14	77.0	COG3462@1|root,COG3462@2|Bacteria,2I22D@201174|Actinobacteria,4F5W8@85017|Promicromonosporaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	ko:K08982	-	-	-	-	ko00000	-	-	-	-
BYD2_k127_6080647_15	365528.KB891208_gene2834	1.914e-07	53.0	COG2141@1|root,COG2141@2|Bacteria,2GMRE@201174|Actinobacteria,4EU7W@85013|Frankiales	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_6080647_3	1906.SFRA_26890	4.001e-141	475.0	COG2268@1|root,COG2268@2|Bacteria,2GK9I@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Band 7 protein	-	-	-	ko:K07192	ko04910,map04910	-	-	-	ko00000,ko00001,ko03036,ko04131,ko04147	-	-	-	Band_7,Flot
BYD2_k127_6080647_13	1122182.KB903815_gene1417	2.964e-17	89.0	2EBIV@1|root,335JA@2|Bacteria,2IHZS@201174|Actinobacteria,4DE5V@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
BYD2_k127_6080647_12	1220534.B655_0851	3.955e-19	98.0	COG0638@1|root,arCOG00970@2157|Archaea,2Y1U9@28890|Euryarchaeota,23PBD@183925|Methanobacteria	183925|Methanobacteria	O	Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6080647_11	1122613.ATUP01000002_gene2661	3.086e-31	136.0	COG0040@1|root,COG0040@2|Bacteria,1MUCY@1224|Proteobacteria,2TT0H@28211|Alphaproteobacteria,43X93@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	HisG, C-terminal domain	hisG	GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.4.2.17	ko:K00765	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG,HisG_C
BYD2_k127_6080647_14	109760.SPPG_02630T0	2.63e-09	68.0	COG0139@1|root,COG0141@1|root,KOG2697@2759|Eukaryota,KOG4311@2759|Eukaryota,38HWK@33154|Opisthokonta,3NURS@4751|Fungi	4751|Fungi	E	Histidine biosynthesis trifunctional protein	HIS4	GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0004635,GO:0004636,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016491,GO:0016614,GO:0016616,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.23,3.5.4.19,3.6.1.31	ko:K14152	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012,R04035,R04037	RC00002,RC00099,RC00242,RC00463,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	-	Histidinol_dh,PRA-CH,PRA-PH
BYD2_k127_6080647_1	1157943.KB892705_gene2248	7.212e-173	571.0	COG0427@1|root,COG0427@2|Bacteria,2IAMG@201174|Actinobacteria,234WQ@1762|Mycobacteriaceae	201174|Actinobacteria	C	acetyl-CoA hydrolase	-	-	-	ko:K18288	ko00660,map00660	-	R02407,R10600	RC00012,RC00014	ko00000,ko00001,ko01000	-	-	-	AcetylCoA_hyd_C,AcetylCoA_hydro
BYD2_k127_6080647_5	570268.ANBB01000064_gene983	6.637e-97	340.0	COG1409@1|root,COG1409@2|Bacteria,2I59J@201174|Actinobacteria,4EHR8@85012|Streptosporangiales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
BYD2_k127_6080647_6	1045009.AFXQ01000011_gene474	2.262e-82	282.0	COG1108@1|root,COG1108@2|Bacteria,2GJ7H@201174|Actinobacteria,1W8TI@1268|Micrococcaceae	201174|Actinobacteria	P	ABC 3 transport family	mntB	-	-	ko:K02075,ko:K09819	-	M00243,M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ABC-3
BYD2_k127_6080647_9	1122238.AULR01000011_gene1557	1.628e-58	226.0	COG0803@1|root,COG0803@2|Bacteria,2GM1K@201174|Actinobacteria,4FMEF@85023|Microbacteriaceae	201174|Actinobacteria	P	Zinc-uptake complex component A periplasmic	mntC	-	-	ko:K02077	-	M00244	-	-	ko00000,ko00002,ko02000	3.A.1.15	-	-	ZnuA
BYD2_k127_6080647_7	1313172.YM304_31180	2.049e-62	225.0	COG1121@1|root,COG1121@2|Bacteria,2GN95@201174|Actinobacteria	201174|Actinobacteria	P	ABC transporter	-	-	-	ko:K11603	ko02010,ko02020,map02010,map02020	M00316	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.15.1	-	-	ABC_tran
BYD2_k127_6080647_10	1229780.BN381_100221	6.28e-43	162.0	COG0735@1|root,COG0735@2|Bacteria	2|Bacteria	P	belongs to the Fur family	-	-	-	ko:K03711	-	-	-	-	ko00000,ko03000	-	-	-	FUR
BYD2_k127_6080647_2	1313172.YM304_18860	7.454e-152	488.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_6080647_0	1385521.N803_08810	2.062e-180	577.0	COG1216@1|root,COG2227@1|root,COG1216@2|Bacteria,COG2227@2|Bacteria,2I2FA@201174|Actinobacteria,4FG2V@85021|Intrasporangiaceae	201174|Actinobacteria	H	Methionine biosynthesis protein MetW	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Methyltransf_23
BYD2_k127_6080647_8	367299.JOEE01000005_gene3530	2.962e-59	231.0	2EJZM@1|root,33DQ6@2|Bacteria,2IBYK@201174|Actinobacteria,4FEH6@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6080647_4	1131269.AQVV01000013_gene1726	9.775e-98	342.0	COG1032@1|root,COG1032@2|Bacteria	2|Bacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,Radical_SAM
BYD2_k127_6083227_6	1429046.RR21198_0088	6.098e-39	163.0	COG0477@1|root,COG0477@2|Bacteria,2GITS@201174|Actinobacteria,4FXZ9@85025|Nocardiaceae	201174|Actinobacteria	EGP	major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
BYD2_k127_6083227_12	1298863.AUEP01000010_gene4453	2.075e-10	66.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4DU1X@85009|Propionibacteriales	201174|Actinobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_6083227_9	1472716.KBK24_0110985	3.946e-16	92.0	COG1752@1|root,COG1752@2|Bacteria,1MX8Y@1224|Proteobacteria,2VKNF@28216|Betaproteobacteria,1K0PA@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_6083227_14	345341.KUTG_09755	1.718e-08	57.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria,4E1GD@85010|Pseudonocardiales	201174|Actinobacteria	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	-	-	1.8.1.4	ko:K00382	ko00010,ko00020,ko00260,ko00280,ko00620,ko00630,ko00640,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00260,map00280,map00620,map00630,map00640,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00036,M00307,M00532	R00209,R01221,R01698,R03815,R07618,R08549	RC00004,RC00022,RC00583,RC02742,RC02833,RC02834	br01601,ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyr_redox_2,Pyr_redox_dim
BYD2_k127_6083227_7	1215092.PA6_009_01080	6.358e-28	123.0	COG0428@1|root,COG0428@2|Bacteria,1QE6Q@1224|Proteobacteria,1S080@1236|Gammaproteobacteria,1YEK9@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	P	transporter	-	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	cNMP_binding
BYD2_k127_6083227_13	1122939.ATUD01000001_gene406	6.856e-10	66.0	COG4177@1|root,COG4177@2|Bacteria,2GJB3@201174|Actinobacteria,4CPB4@84995|Rubrobacteria	84995|Rubrobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_6083227_10	204669.Acid345_3725	2.408e-14	79.0	COG2041@1|root,COG2041@2|Bacteria,3Y85H@57723|Acidobacteria	57723|Acidobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
BYD2_k127_6083227_16	1157632.AQWQ01000003_gene1697	0.0007289	49.0	COG2353@1|root,COG2353@2|Bacteria,2GJFT@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	CarboxypepD_reg,YceI
BYD2_k127_6083227_8	981369.JQMJ01000004_gene4453	1.028e-21	98.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria,2NHUJ@228398|Streptacidiphilus	201174|Actinobacteria	S	YceI-like domain	yceI	-	-	-	-	-	-	-	-	-	-	-	YceI
BYD2_k127_6083227_3	1283283.ATXA01000001_gene431	4.445e-96	316.0	COG0225@1|root,COG0225@2|Bacteria,2GJ1S@201174|Actinobacteria,4ERSD@85013|Frankiales	201174|Actinobacteria	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0016491,GO:0016667,GO:0016671,GO:0020012,GO:0030682,GO:0033744,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0075136	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,SelR
BYD2_k127_6083227_5	1464048.JNZS01000003_gene1057	1.03e-43	166.0	COG2128@1|root,COG2128@2|Bacteria,2IG23@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_6083227_4	1121362.A605_14482	7.472e-48	175.0	COG1145@1|root,32SB1@2|Bacteria,2IJFQ@201174|Actinobacteria,22N61@1653|Corynebacteriaceae	201174|Actinobacteria	C	Domain of Unknown Function (DUF326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF326
BYD2_k127_6083227_0	298654.FraEuI1c_0553	1.144e-198	653.0	COG2197@1|root,COG2197@2|Bacteria,2IC7E@201174|Actinobacteria,4EXDN@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein LuxR	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_6083227_1	1123024.AUII01000024_gene194	2.183e-162	531.0	COG2508@1|root,COG2508@2|Bacteria,2GM1G@201174|Actinobacteria	201174|Actinobacteria	QT	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
BYD2_k127_6083227_15	1173264.KI913949_gene49	1.639e-05	54.0	COG1633@1|root,COG1633@2|Bacteria,1G5G8@1117|Cyanobacteria,1HAKN@1150|Oscillatoriales	1117|Cyanobacteria	S	Domain of unknown function (DUF4439)	-	-	-	-	-	-	-	-	-	-	-	-	Ferritin_2
BYD2_k127_6083227_2	1380390.JIAT01000010_gene3842	5.189e-99	324.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4CSS2@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_613256_6	216594.MMAR_0235	5.562e-14	72.0	2BHD5@1|root,32BF1@2|Bacteria,2GUXJ@201174|Actinobacteria,2383B@1762|Mycobacteriaceae	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_613256_5	479434.Sthe_2962	5.262e-25	118.0	COG3467@1|root,COG3467@2|Bacteria	2|Bacteria	T	pyridoxamine 5'-phosphate	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Putative_PNPOx,Pyridox_ox_2
BYD2_k127_613256_3	479433.Caci_3578	2.011e-42	164.0	2DN3W@1|root,32VDG@2|Bacteria,2I477@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_613256_2	1206744.BAGL01000032_gene9	9.273e-49	180.0	COG3467@1|root,COG3467@2|Bacteria,2IAMC@201174|Actinobacteria,4FVEJ@85025|Nocardiaceae	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyridox_ox_2
BYD2_k127_613256_1	313589.JNB_12144	1.257e-71	248.0	COG1733@1|root,COG1733@2|Bacteria,2GMQG@201174|Actinobacteria,4FJ1K@85021|Intrasporangiaceae	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
BYD2_k127_613256_4	1380393.JHVP01000007_gene4254	1.503e-31	126.0	COG0262@1|root,COG0262@2|Bacteria,2I8GU@201174|Actinobacteria,4EW9Q@85013|Frankiales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_613256_0	290399.Arth_3711	7.018e-99	325.0	COG0454@1|root,COG0456@2|Bacteria,2GY1D@201174|Actinobacteria,1WAUV@1268|Micrococcaceae	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_6150565_9	345341.KUTG_00776	1.305e-47	181.0	COG0583@1|root,COG0583@2|Bacteria,2IE46@201174|Actinobacteria,4E1G7@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BYD2_k127_6150565_12	979556.MTES_3609	2.488e-20	99.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_6150565_5	1128421.JAGA01000003_gene3343	2.101e-104	357.0	COG0654@1|root,COG0654@2|Bacteria	2|Bacteria	CH	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases	-	GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016020,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0030312,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	1.14.13.2	ko:K00481	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R01298	RC00046	ko00000,ko00001,ko01000	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored,Trp_halogenase
BYD2_k127_6150565_2	479434.Sthe_1229	3.01e-181	586.0	COG2197@1|root,COG2197@2|Bacteria	2|Bacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BYD2_k127_6150565_10	1313172.YM304_17370	3.345e-24	106.0	2FIWN@1|root,34AMS@2|Bacteria,2H89S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6150565_4	1157637.KB892120_gene346	7.644e-135	452.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	mcl2	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI,PEP-utilizers_C
BYD2_k127_6150565_1	1313172.YM304_14270	6.046e-184	580.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4CNND@84992|Acidimicrobiia	84992|Acidimicrobiia	G	HpcH/HpaI aldolase/citrate lyase family	-	-	4.1.3.24,4.1.3.25,4.1.3.34	ko:K01644,ko:K08691	ko00630,ko00660,ko00680,ko00720,ko01120,ko01200,ko02020,map00630,map00660,map00680,map00720,map01120,map01200,map02020	M00346,M00373,M00376	R00237,R00362,R00473,R00934	RC00067,RC00307,RC00308,RC00311,RC00407,RC00502,RC01118,RC01205	ko00000,ko00001,ko00002,ko01000	-	-	-	HpcH_HpaI
BYD2_k127_6150565_0	1464048.JNZS01000027_gene1949	2.442e-282	878.0	COG3387@1|root,COG3387@2|Bacteria,2GJAD@201174|Actinobacteria,4D8XJ@85008|Micromonosporales	201174|Actinobacteria	G	Glycoside hydrolase 15-related	wcoR	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_15
BYD2_k127_6150565_8	196162.Noca_4873	1.26e-74	254.0	2AZF8@1|root,31RP4@2|Bacteria,2IH9G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6150565_3	1048339.KB913029_gene2691	1.587e-139	454.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria,4ES0A@85013|Frankiales	201174|Actinobacteria	S	PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase	fprD	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
BYD2_k127_6150565_6	68170.KL590477_gene2384	5.688e-98	338.0	COG4805@1|root,COG4805@2|Bacteria,2GJQT@201174|Actinobacteria,4DYBW@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6150565_7	1121877.JQKF01000003_gene1502	2.557e-76	261.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4CN01@84992|Acidimicrobiia	84992|Acidimicrobiia	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
BYD2_k127_6150565_13	1449049.JONW01000005_gene1479	2.694e-08	64.0	COG1051@1|root,COG1051@2|Bacteria,1N1XV@1224|Proteobacteria,2UDI0@28211|Alphaproteobacteria,2KGZJ@204458|Caulobacterales	204458|Caulobacterales	F	Belongs to the Nudix hydrolase family	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
BYD2_k127_6150565_11	1089546.AQUI01000002_gene687	1.37e-21	105.0	COG3170@1|root,COG3170@2|Bacteria,2ICMF@201174|Actinobacteria	201174|Actinobacteria	NU	Tfp pilus assembly protein FimV	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6157342_6	1313172.YM304_04070	4.974e-41	153.0	COG0377@1|root,COG0377@2|Bacteria,2GJXR@201174|Actinobacteria,4CMXA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00331	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q6
BYD2_k127_6157342_5	1313172.YM304_04080	1.848e-52	192.0	COG0852@1|root,COG0852@2|Bacteria,2GIRH@201174|Actinobacteria,4CN4G@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Respiratory-chain NADH dehydrogenase, 30 Kd subunit	-	-	1.6.5.3	ko:K00332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_30kDa
BYD2_k127_6157342_1	1313172.YM304_04090	5.969e-219	687.0	COG0649@1|root,COG0649@2|Bacteria,2GKEZ@201174|Actinobacteria,4CMP9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00333	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_49kDa
BYD2_k127_6157342_4	1313172.YM304_04100	1.54e-66	250.0	COG1905@1|root,COG1905@2|Bacteria,2GKG0@201174|Actinobacteria,4CN1U@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Thioredoxin-like [2Fe-2S] ferredoxin	nuoE	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
BYD2_k127_6157342_2	1229780.BN381_160006	3.694e-187	606.0	COG1894@1|root,COG1894@2|Bacteria,2GMMC@201174|Actinobacteria,3UWD5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region	nuoF	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Complex1_51K,NADH_4Fe-4S,SLBB
BYD2_k127_6157342_0	1229780.BN381_160007	3.058e-285	916.0	COG1034@1|root,COG1034@2|Bacteria,2GJGX@201174|Actinobacteria,3UWBF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region	nuoG	GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer2_4,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
BYD2_k127_6157342_3	1229780.BN381_160008	1.901e-153	503.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,3UW85@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	nuoH	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3152	NADHdh
BYD2_k127_6157342_7	1229780.BN381_160009	1.98e-29	128.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,3UWSS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoI	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944	1.6.5.3	ko:K00338,ko:K12143	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	iNJ661.Rv3153	Fer4
BYD2_k127_6160733_3	666684.AfiDRAFT_0065	5.383e-111	368.0	COG0403@1|root,COG1003@1|root,COG0403@2|Bacteria,COG1003@2|Bacteria,1MUDP@1224|Proteobacteria,2TSFF@28211|Alphaproteobacteria,3JUAJ@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor	gcvP	-	1.4.4.2	ko:K00281,ko:K00283	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221,R03425	RC00022,RC00929,RC02834,RC02880	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_5,GDC-P
BYD2_k127_6160733_4	1089545.KB913037_gene7342	4.886e-107	376.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4E1PX@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
BYD2_k127_6160733_0	1120949.KB903307_gene1400	1.577e-163	554.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4D8PE@85008|Micromonosporales	201174|Actinobacteria	S	epoxide hydrolase	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
BYD2_k127_6160733_2	1120950.KB892708_gene4319	8.122e-121	404.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4DREI@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
BYD2_k127_6160733_11	1313172.YM304_41480	1.628e-09	68.0	COG1277@1|root,COG1277@2|Bacteria,2GK3E@201174|Actinobacteria	201174|Actinobacteria	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2,ABC2_membrane_4
BYD2_k127_6160733_5	479434.Sthe_1081	4.9e-78	287.0	COG1131@1|root,COG1131@2|Bacteria,2G6B8@200795|Chloroflexi	200795|Chloroflexi	V	PFAM ABC transporter related	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_6160733_9	436229.JOEH01000009_gene4370	5.008e-30	139.0	COG1277@1|root,COG1277@2|Bacteria,2GKKP@201174|Actinobacteria,2NG0R@228398|Streptacidiphilus	201174|Actinobacteria	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
BYD2_k127_6160733_6	58123.JOFJ01000024_gene3460	8.624e-75	264.0	COG1131@1|root,COG1131@2|Bacteria,2GKWB@201174|Actinobacteria,4EIF9@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_6160733_10	526225.Gobs_2710	1.218e-14	79.0	2E5E7@1|root,33065@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6160733_8	37919.EP51_04125	1.042e-41	174.0	COG3795@1|root,COG3795@2|Bacteria,2IQMR@201174|Actinobacteria,4G2IT@85025|Nocardiaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_6160733_1	1394178.AWOO02000001_gene1397	1.068e-152	499.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_6160733_7	219305.MCAG_00219	1.576e-73	256.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria,4DE41@85008|Micromonosporales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_6171535_2	1184607.AUCHE_08_00990	8.197e-18	85.0	COG3547@1|root,COG3547@2|Bacteria,2GNQB@201174|Actinobacteria,4F7BF@85018|Dermatophilaceae	201174|Actinobacteria	L	Transposase	-	-	-	ko:K07486	-	-	-	-	ko00000	-	-	-	DEDD_Tnp_IS110,Transposase_20
BYD2_k127_6171535_3	1122138.AQUZ01000006_gene1370	0.0004679	46.0	295TY@1|root,2ZT51@2|Bacteria,2HC2W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6171535_1	1211815.CBYP010000066_gene1591	3.749e-28	126.0	2C6J1@1|root,33H0F@2|Bacteria,2IMXS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6171535_0	452637.Oter_3673	3.777e-244	790.0	COG2982@1|root,COG2982@2|Bacteria,46XH6@74201|Verrucomicrobia,3KA1C@414999|Opitutae	414999|Opitutae	M	Protein involved in outer membrane biogenesis	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_2	1313172.YM304_31600	3.611e-188	612.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CNHT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_6230800_43	1449976.KALB_4456	1.452e-27	119.0	COG1309@1|root,COG1309@2|Bacteria,2HG87@201174|Actinobacteria,4E69G@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_6230800_18	298655.KI912266_gene2338	1.411e-79	268.0	COG3467@1|root,COG3467@2|Bacteria,2IFJS@201174|Actinobacteria	201174|Actinobacteria	S	pyridoxamine 5-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_6230800_7	1394178.AWOO02000056_gene772	2.23e-147	484.0	COG1304@1|root,COG1304@2|Bacteria,2GJA5@201174|Actinobacteria,4EIB7@85012|Streptosporangiales	201174|Actinobacteria	C	FMN-dependent dehydrogenase	lldA	-	1.13.12.4	ko:K00467	ko00620,map00620	-	R00319	RC01312	ko00000,ko00001,ko01000	-	-	-	FMN_dh
BYD2_k127_6230800_39	861299.J421_0224	3.492e-34	148.0	COG5001@1|root,COG5001@2|Bacteria,1ZT12@142182|Gemmatimonadetes	2|Bacteria	T	Putative diguanylate phosphodiesterase	-	-	2.7.7.65	ko:K21021	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000	-	-	-	GGDEF
BYD2_k127_6230800_36	1500893.JQNB01000001_gene1375	8.802e-42	160.0	COG0563@1|root,COG0563@2|Bacteria,1MXCZ@1224|Proteobacteria,1RMT6@1236|Gammaproteobacteria,1X668@135614|Xanthomonadales	135614|Xanthomonadales	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK
BYD2_k127_6230800_4	479433.Caci_2646	4.671e-159	518.0	28KUD@1|root,2ZAB6@2|Bacteria,2IACK@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_9	768671.ThimaDRAFT_2858	7.794e-130	424.0	COG1087@1|root,COG1087@2|Bacteria,1MUHI@1224|Proteobacteria,1RMTU@1236|Gammaproteobacteria,1WWNR@135613|Chromatiales	135613|Chromatiales	M	Belongs to the NAD(P)-dependent epimerase dehydratase family	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
BYD2_k127_6230800_14	1048339.KB913029_gene3698	3.448e-119	395.0	COG1024@1|root,COG1024@2|Bacteria,2GJ1A@201174|Actinobacteria,4EURW@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA15	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_6230800_23	67257.JODR01000027_gene2839	1.404e-66	245.0	2DBXI@1|root,2ZBQ3@2|Bacteria,2GJN1@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50B
BYD2_k127_6230800_31	479432.Sros_7540	1.58e-49	190.0	COG1309@1|root,COG1309@2|Bacteria,2HP60@201174|Actinobacteria,4EQA5@85012|Streptosporangiales	201174|Actinobacteria	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
BYD2_k127_6230800_26	656024.FsymDg_0030	1.137e-60	215.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
BYD2_k127_6230800_1	1313172.YM304_13260	5.18e-192	605.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,4CNIG@84992|Acidimicrobiia	2|Bacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_6230800_55	526226.Gbro_0433	6.305e-07	55.0	2FJQ4@1|root,34BD5@2|Bacteria,2GU4Y@201174|Actinobacteria,4GF3N@85026|Gordoniaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1330
BYD2_k127_6230800_47	1121926.AXWO01000019_gene1866	1.995e-23	109.0	COG0711@1|root,COG0711@2|Bacteria	2|Bacteria	C	ATP synthesis coupled proton transport	-	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	-
BYD2_k127_6230800_41	1121926.AXWO01000019_gene1867	3.135e-30	134.0	2DMSR@1|root,32TF3@2|Bacteria,2IR08@201174|Actinobacteria,4F02K@85014|Glycomycetales	201174|Actinobacteria	S	Putative Actinobacterial Holin-X, holin superfamily III	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_3_6
BYD2_k127_6230800_40	1306406.ASHX01000002_gene5199	4.411e-34	143.0	2B9CE@1|root,2ZB7A@2|Bacteria,2I2DB@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3618)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3618
BYD2_k127_6230800_32	196162.Noca_3162	3.963e-49	188.0	COG1296@1|root,COG1296@2|Bacteria,2GN6R@201174|Actinobacteria,4DQH9@85009|Propionibacteriales	201174|Actinobacteria	E	AzlC protein	-	-	-	-	-	-	-	-	-	-	-	-	AzlC
BYD2_k127_6230800_53	479431.Namu_2769	8.929e-10	70.0	2E45J@1|root,32Z1K@2|Bacteria,2GR89@201174|Actinobacteria,4ETFI@85013|Frankiales	201174|Actinobacteria	S	Branched-chain amino acid transport	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
BYD2_k127_6230800_49	1944.JOAZ01000002_gene5407	2.624e-15	81.0	COG2172@1|root,COG2172@2|Bacteria,2IR0B@201174|Actinobacteria,41CNX@629295|Streptomyces griseus group	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2
BYD2_k127_6230800_21	1313172.YM304_25150	8.482e-72	263.0	28TMQ@1|root,3459Q@2|Bacteria,2H8NA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_8	414684.RC1_3167	1.474e-133	452.0	COG1171@1|root,COG1171@2|Bacteria,1MVWJ@1224|Proteobacteria,2TQN9@28211|Alphaproteobacteria,2JPM3@204441|Rhodospirillales	204441|Rhodospirillales	E	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4,PALP
BYD2_k127_6230800_16	2002.JOEQ01000023_gene1191	3.401e-109	371.0	COG4948@1|root,COG4948@2|Bacteria,2GJJR@201174|Actinobacteria,4EG9K@85012|Streptosporangiales	201174|Actinobacteria	M	Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB)	menC	-	4.2.1.113	ko:K02549	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116	R04031	RC01053	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
BYD2_k127_6230800_10	1297742.A176_06381	2.2e-125	408.0	COG0024@1|root,COG0024@2|Bacteria,1MU99@1224|Proteobacteria,42MM5@68525|delta/epsilon subdivisions,2WJMN@28221|Deltaproteobacteria	28221|Deltaproteobacteria	J	TIGRFAM methionine aminopeptidase, type I	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
BYD2_k127_6230800_3	1313172.YM304_22580	4.702e-172	560.0	COG1164@1|root,COG1164@2|Bacteria,2IGPX@201174|Actinobacteria	201174|Actinobacteria	E	Oligopeptidase F	pepF	-	-	ko:K08602	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M3,Peptidase_M3_N
BYD2_k127_6230800_52	1298863.AUEP01000018_gene3913	1.675e-10	64.0	2EI4A@1|root,33BVN@2|Bacteria,2GX45@201174|Actinobacteria,4DSKQ@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_12	469383.Cwoe_1487	8.768e-123	406.0	COG3214@1|root,COG3214@2|Bacteria,2GJM7@201174|Actinobacteria,4CPIN@84995|Rubrobacteria	84995|Rubrobacteria	S	Winged helix DNA-binding domain	-	-	-	ko:K09927	-	-	-	-	ko00000	-	-	-	HTH_42
BYD2_k127_6230800_45	1123024.AUII01000015_gene3758	3.961e-24	103.0	COG1141@1|root,COG1141@2|Bacteria,2GT1Y@201174|Actinobacteria	201174|Actinobacteria	C	Divergent 4Fe-4S mono-cluster	fdxD_2	-	-	ko:K05337	-	-	-	-	ko00000	-	-	-	Fer4_13,Fer4_15
BYD2_k127_6230800_13	326424.FRAAL4010	9.98e-120	400.0	COG0446@1|root,COG0446@2|Bacteria,2GJKT@201174|Actinobacteria	201174|Actinobacteria	Q	pyridine nucleotide-disulphide oxidoreductase	-	-	1.18.1.3	ko:K00529	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	Pyr_redox_2,Reductase_C
BYD2_k127_6230800_38	1229780.BN381_250093	3.178e-36	158.0	COG3714@1|root,COG3714@2|Bacteria	2|Bacteria	S	YhhN family	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
BYD2_k127_6230800_24	1341646.CBMO010000001_gene1597	5.545e-63	218.0	COG3740@1|root,COG3740@2|Bacteria,2II2M@201174|Actinobacteria,239DQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Phage prohead protease, HK97 family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_46	1122182.KB903834_gene6024	1.692e-23	111.0	COG1073@1|root,COG1073@2|Bacteria,2GNUS@201174|Actinobacteria,4DD5U@85008|Micromonosporales	201174|Actinobacteria	S	X-Pro dipeptidyl-peptidase (S15 family)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6,Hydrolase_4
BYD2_k127_6230800_30	479432.Sros_1912	8.573e-51	188.0	COG2917@1|root,COG2917@2|Bacteria,2IGTQ@201174|Actinobacteria,4EIRE@85012|Streptosporangiales	201174|Actinobacteria	D	probably involved in intracellular septation	-	-	-	-	-	-	-	-	-	-	-	-	DUF3159,IspA
BYD2_k127_6230800_0	1229780.BN381_250091	2.519e-221	718.0	COG0308@1|root,COG0308@2|Bacteria,2GJJ4@201174|Actinobacteria,3UWD9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	ERAP1-like C-terminal domain	pepN	-	3.4.11.2	ko:K01256,ko:K08776	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	ERAP1_C,Peptidase_M1
BYD2_k127_6230800_15	1205680.CAKO01000040_gene852	6.288e-116	384.0	COG0524@1|root,COG0524@2|Bacteria,1MUUC@1224|Proteobacteria,2TS9D@28211|Alphaproteobacteria,2JPGW@204441|Rhodospirillales	204441|Rhodospirillales	G	COG0524 Sugar kinases, ribokinase family	pfkB	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
BYD2_k127_6230800_19	477641.MODMU_0261	2.176e-77	297.0	COG3629@1|root,COG3899@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,COG3903@2|Bacteria,2I2U4@201174|Actinobacteria,4EUMV@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
BYD2_k127_6230800_35	267608.RSc1841	4.051e-42	177.0	COG0596@1|root,COG0596@2|Bacteria,1R8PJ@1224|Proteobacteria,2VNAT@28216|Betaproteobacteria	28216|Betaproteobacteria	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_6230800_51	1229780.BN381_130349	1.886e-13	84.0	COG2755@1|root,COG2755@2|Bacteria,2HFQG@201174|Actinobacteria,3UXQ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
BYD2_k127_6230800_29	1283299.AUKG01000002_gene4715	1.013e-54	216.0	COG2837@1|root,COG2837@2|Bacteria,2GND2@201174|Actinobacteria	201174|Actinobacteria	P	Dyp-type peroxidase family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_54	1306174.JODP01000006_gene3326	9.496e-10	71.0	2DBRK@1|root,2ZAME@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_44	211114.JOEF01000005_gene2105	2.081e-27	129.0	COG0753@1|root,COG0753@2|Bacteria,2GN9F@201174|Actinobacteria,4E32Z@85010|Pseudonocardiales	201174|Actinobacteria	P	Has an organic peroxide-dependent peroxidase activity	-	GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019222,GO:0020037,GO:0031323,GO:0042221,GO:0042743,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050789,GO:0050794,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0065007,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1990748,GO:2000377	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
BYD2_k127_6230800_20	1489678.RDMS_11215	1.625e-76	271.0	COG3507@1|root,COG3507@2|Bacteria	2|Bacteria	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
BYD2_k127_6230800_37	525909.Afer_0695	9.552e-41	156.0	COG3576@1|root,COG3576@2|Bacteria,2II3S@201174|Actinobacteria,4CNCN@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_6230800_22	1150864.MILUP08_42160	6.902e-67	247.0	COG2318@1|root,COG2318@2|Bacteria,2II1I@201174|Actinobacteria,4DE55@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function (DUF664)	-	-	-	-	-	-	-	-	-	-	-	-	DUF664,DinB_2
BYD2_k127_6230800_27	266117.Rxyl_0189	5.27e-60	222.0	COG0697@1|root,COG0697@2|Bacteria,2GMPJ@201174|Actinobacteria,4CQ3D@84995|Rubrobacteria	84995|Rubrobacteria	EG	EamA-like transporter family	-	-	-	ko:K03298	-	-	-	-	ko00000,ko02000	2.A.7.3	-	-	EamA
BYD2_k127_6230800_34	644966.Tmar_1538	2.765e-42	169.0	2BY2H@1|root,32R2G@2|Bacteria,1VUIG@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_33	1449048.JQKU01000001_gene2328	5.951e-46	190.0	COG3324@1|root,COG3324@2|Bacteria,2I6WX@201174|Actinobacteria,233G3@1762|Mycobacteriaceae	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6230800_28	649638.Trad_0374	1.812e-56	225.0	KOG2524@1|root,2ZJ84@2|Bacteria	2|Bacteria	S	Potential Queuosine, Q, salvage protein family	-	-	-	-	-	-	-	-	-	-	-	-	Q_salvage
BYD2_k127_6230800_6	886293.Sinac_5044	2.776e-148	510.0	COG1505@1|root,COG1505@2|Bacteria,2IXRJ@203682|Planctomycetes	203682|Planctomycetes	E	Prolyl oligopeptidase	-	-	3.4.21.26	ko:K01322	ko04614,map04614	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S9,Peptidase_S9_N
BYD2_k127_6230800_42	101510.RHA1_ro00631	2.448e-29	132.0	2EUVM@1|root,33NB3@2|Bacteria,2GTGH@201174|Actinobacteria,4G0N0@85025|Nocardiaceae	201174|Actinobacteria	S	RES domain	-	-	-	-	-	-	-	-	-	-	-	-	RES
BYD2_k127_6230800_48	1454010.JEOE01000004_gene57	1.719e-15	85.0	2DNKR@1|root,32Y0D@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2384
BYD2_k127_6230800_11	1298880.AUEV01000014_gene3831	3.836e-124	406.0	COG1387@1|root,COG1387@2|Bacteria,2GMFH@201174|Actinobacteria	201174|Actinobacteria	E	PHP domain	polX	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	HHH_8,PHP
BYD2_k127_6230800_50	1317118.ATO8_11169	1.598e-14	82.0	COG2968@1|root,COG2968@2|Bacteria,1RH7T@1224|Proteobacteria,2U981@28211|Alphaproteobacteria,4KMRP@93682|Roseivivax	28211|Alphaproteobacteria	S	Protein of unknown function (DUF541)	omp28	GO:0005575,GO:0005623,GO:0042597,GO:0044464	-	ko:K09807	-	-	-	-	ko00000	-	-	-	SIMPL
BYD2_k127_6230800_5	1229780.BN381_20071	3.713e-152	497.0	COG0012@1|root,COG0012@2|Bacteria,2GIXI@201174|Actinobacteria,3UWA3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
BYD2_k127_6230800_25	44454.NF84_10005	1.532e-61	222.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,23F6N@1762|Mycobacteriaceae	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_6243066_25	1206732.BAGD01000023_gene417	2.658e-43	163.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4FV1F@85025|Nocardiaceae	201174|Actinobacteria	EGP	the major facilitator superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
BYD2_k127_6243066_17	298653.Franean1_0479	2.289e-60	214.0	COG1309@1|root,COG1309@2|Bacteria,2GJBV@201174|Actinobacteria,4EWF0@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_13,TetR_N
BYD2_k127_6243066_24	1229780.BN381_10211	2.848e-44	171.0	2CIFA@1|root,348QY@2|Bacteria,2H88E@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6243066_8	861299.J421_3230	3.756e-113	403.0	COG0728@1|root,COG0728@2|Bacteria,1ZTCM@142182|Gemmatimonadetes	142182|Gemmatimonadetes	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	murJ	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
BYD2_k127_6243066_15	1229780.BN381_10209	6.026e-83	284.0	COG1842@1|root,COG1842@2|Bacteria,2GJGD@201174|Actinobacteria	201174|Actinobacteria	KT	Phage shock protein A	pspA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044464,GO:0071944	-	ko:K03969	-	-	-	-	ko00000	-	-	-	PspA_IM30
BYD2_k127_6243066_12	390989.JOEG01000019_gene5973	2.955e-95	329.0	COG0566@1|root,COG0566@2|Bacteria,2GM1A@201174|Actinobacteria,4DB7B@85008|Micromonosporales	201174|Actinobacteria	J	tRNA rRNA methyltransferase	trmH	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
BYD2_k127_6243066_13	1384054.N790_04610	7.45e-93	321.0	2C3PP@1|root,2Z954@2|Bacteria,1MXGR@1224|Proteobacteria,1S3GQ@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Branched-chain amino acid aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6243066_3	1121013.P873_04260	2.527e-148	477.0	COG0115@1|root,COG0115@2|Bacteria,1MVB0@1224|Proteobacteria,1RQZ9@1236|Gammaproteobacteria,1X85P@135614|Xanthomonadales	135614|Xanthomonadales	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
BYD2_k127_6243066_20	1043205.AFYF01000087_gene1150	1.602e-50	193.0	COG0454@1|root,COG0456@2|Bacteria,2I8DS@201174|Actinobacteria	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_6243066_18	1211815.CBYP010000063_gene1853	5.84e-55	196.0	COG3631@1|root,COG3631@2|Bacteria,2IHRM@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_2
BYD2_k127_6243066_9	585531.HMPREF0063_12556	1.699e-108	361.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria,4DPXS@85009|Propionibacteriales	201174|Actinobacteria	IQ	KR domain	hdhA	GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136	1.1.1.159	ko:K00076	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
BYD2_k127_6243066_19	1123024.AUII01000031_gene526	1.565e-52	192.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4E6FQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
BYD2_k127_6243066_5	1246448.ANAZ01000048_gene3281	1.715e-129	438.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria	201174|Actinobacteria	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
BYD2_k127_6243066_16	101510.RHA1_ro03727	2.798e-68	239.0	COG0412@1|root,COG0412@2|Bacteria,2GNWB@201174|Actinobacteria,4FW2S@85025|Nocardiaceae	201174|Actinobacteria	Q	Dienelactone hydrolase family	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
BYD2_k127_6243066_7	1229780.BN381_10208	1.225e-115	404.0	COG0263@1|root,COG0263@2|Bacteria,2GM8U@201174|Actinobacteria,3UWHH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
BYD2_k127_6243066_2	1229780.BN381_10207	1.223e-160	528.0	COG0536@1|root,COG0536@2|Bacteria,2GISB@201174|Actinobacteria,3UWET@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	GO:0000287,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019538,GO:0032991,GO:0036211,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046777,GO:0046872,GO:0071704,GO:0071944,GO:1901564,GO:1990904	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
BYD2_k127_6243066_23	1229780.BN381_310007	5.378e-47	191.0	COG1024@1|root,COG1024@2|Bacteria,2I9VC@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_6243066_29	1205910.B005_0483	7.912e-31	131.0	COG0211@1|root,COG0211@2|Bacteria,2IQDI@201174|Actinobacteria,4EJZP@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
BYD2_k127_6243066_28	1229780.BN381_80103	2.156e-31	126.0	COG0261@1|root,COG0261@2|Bacteria,2IQ9A@201174|Actinobacteria,3UWVG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
BYD2_k127_6243066_4	269800.Tfu_2183	8.393e-133	446.0	COG1530@1|root,COG1530@2|Bacteria,2GMM5@201174|Actinobacteria,4EGIT@85012|Streptosporangiales	201174|Actinobacteria	J	Ribonuclease E/G family	rne	-	3.1.26.12	ko:K08300,ko:K08301	ko03018,map03018	M00394	-	-	ko00000,ko00001,ko00002,ko01000,ko03009,ko03019	-	-	-	IF2_N,RNase_E_G,S1
BYD2_k127_6243066_21	1229780.BN381_80101	1.815e-50	196.0	COG5011@1|root,COG5011@2|Bacteria,2GIS7@201174|Actinobacteria,3UXQA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterized protein conserved in bacteria (DUF2344)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
BYD2_k127_6243066_0	1313172.YM304_18420	7.891e-306	948.0	COG1032@1|root,COG1032@2|Bacteria,2GJY1@201174|Actinobacteria	201174|Actinobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
BYD2_k127_6243066_14	1229780.BN381_80099	1.5e-86	301.0	COG0772@1|root,COG0772@2|Bacteria,2GK2G@201174|Actinobacteria,3UX8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Cell cycle protein	mrdB	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
BYD2_k127_6243066_6	525909.Afer_0769	2.661e-124	429.0	COG0768@1|root,COG0768@2|Bacteria,2GJ61@201174|Actinobacteria,4CMYJ@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Penicillin-binding Protein dimerisation domain	-	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
BYD2_k127_6243066_30	1229780.BN381_80097	6.495e-11	70.0	COG2891@1|root,COG2891@2|Bacteria	2|Bacteria	M	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins	mreD	GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
BYD2_k127_6243066_26	1229780.BN381_80096	2.385e-38	163.0	COG1792@1|root,COG1792@2|Bacteria	2|Bacteria	M	regulation of cell shape	mreC	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0009273,GO:0009987,GO:0016020,GO:0022603,GO:0022604,GO:0030428,GO:0042546,GO:0043621,GO:0044085,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071554,GO:0071840,GO:0071944	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
BYD2_k127_6243066_1	1121877.JQKF01000001_gene1382	9.285e-165	526.0	COG1077@1|root,COG1077@2|Bacteria,2GMD1@201174|Actinobacteria,4CMUQ@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Cell division protein FtsA	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
BYD2_k127_6243066_27	1211815.CBYP010000006_gene276	2.864e-32	136.0	2EN76@1|root,33FV1@2|Bacteria,2GYKJ@201174|Actinobacteria,4ETHS@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6243066_22	555079.Toce_1649	8.624e-49	181.0	COG0105@1|root,COG0105@2|Bacteria,1V44G@1239|Firmicutes,24JM5@186801|Clostridia,42G92@68295|Thermoanaerobacterales	186801|Clostridia	F	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate	ndk	-	2.7.4.6	ko:K00940	ko00230,ko00240,ko00983,ko01100,ko01110,ko01130,ko04016,map00230,map00240,map00983,map01100,map01110,map01130,map04016	M00049,M00050,M00052,M00053	R00124,R00139,R00156,R00330,R00570,R00722,R01137,R01857,R02093,R02326,R02331,R03530,R11894,R11895	RC00002	ko00000,ko00001,ko00002,ko01000,ko04131	-	-	-	NDK
BYD2_k127_6243066_10	1313172.YM304_18330	6.241e-106	368.0	COG0285@1|root,COG0285@2|Bacteria,2GJP2@201174|Actinobacteria,4CNAR@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mur ligase middle domain	-	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_M
BYD2_k127_6243066_11	2002.JOEQ01000021_gene6733	1.942e-100	331.0	COG1219@1|root,COG1219@2|Bacteria,2GJXQ@201174|Actinobacteria,4EI0M@85012|Streptosporangiales	201174|Actinobacteria	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
BYD2_k127_6249802_9	1306174.JODP01000001_gene5367	0.0002764	51.0	COG1716@1|root,COG1716@2|Bacteria,2GU09@201174|Actinobacteria	201174|Actinobacteria	T	ATPase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6249802_8	1120934.KB894427_gene1043	7.18e-17	95.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,4E9UT@85010|Pseudonocardiales	201174|Actinobacteria	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Pkinase
BYD2_k127_6249802_5	1122182.KB903834_gene6181	1.433e-65	244.0	COG0771@1|root,COG0771@2|Bacteria,2GJZA@201174|Actinobacteria,4D91Y@85008|Micromonosporales	201174|Actinobacteria	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
BYD2_k127_6249802_2	656024.FsymDg_3109	4.243e-172	556.0	COG1365@1|root,COG1365@2|Bacteria,2GR2T@201174|Actinobacteria,4EVC9@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6249802_3	656024.FsymDg_3108	3.403e-78	288.0	COG1496@1|root,COG1496@2|Bacteria,2GN1M@201174|Actinobacteria,4ESKN@85013|Frankiales	201174|Actinobacteria	S	Belongs to the multicopper oxidase YfiH RL5 family	yfiH	GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0071944	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
BYD2_k127_6249802_6	765912.Thimo_1861	3.415e-46	186.0	COG0693@1|root,COG0693@2|Bacteria,1MY0C@1224|Proteobacteria,1S3SC@1236|Gammaproteobacteria,1X2HA@135613|Chromatiales	135613|Chromatiales	S	DJ-1/PfpI family	-	-	3.5.1.124	ko:K05520	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
BYD2_k127_6249802_7	1144305.PMI02_03553	1.318e-22	113.0	COG1807@1|root,COG1807@2|Bacteria,1RM6R@1224|Proteobacteria,2USPP@28211|Alphaproteobacteria,2K8AC@204457|Sphingomonadales	204457|Sphingomonadales	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
BYD2_k127_6249802_0	298655.KI912266_gene3128	6.484e-216	701.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria,4EUWU@85013|Frankiales	201174|Actinobacteria	S	PFAM Amidohydrolase 2	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_6249802_1	298654.FraEuI1c_4207	7.764e-213	669.0	COG0683@1|root,COG0683@2|Bacteria,2IAAV@201174|Actinobacteria	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
BYD2_k127_6249802_4	298655.KI912266_gene6120	5.781e-73	271.0	2F48B@1|root,33WZ6@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	NIPSNAP
BYD2_k127_6269990_2	1032480.MLP_00690	1.378e-14	80.0	COG0420@1|root,COG0420@2|Bacteria,2GK9R@201174|Actinobacteria,4DTJP@85009|Propionibacteriales	201174|Actinobacteria	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
BYD2_k127_6269990_0	390989.JOEG01000012_gene3414	1.815e-131	454.0	COG0419@1|root,COG0419@2|Bacteria,2GKYR@201174|Actinobacteria,4DA3T@85008|Micromonosporales	201174|Actinobacteria	L	Putative exonuclease SbcCD, C subunit	sbcC	-	-	ko:K03546	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SbcCD_C
BYD2_k127_6269990_1	749927.AMED_1717	4.915e-41	165.0	COG2380@1|root,COG2380@2|Bacteria,2I8F9@201174|Actinobacteria,4E8J3@85010|Pseudonocardiales	201174|Actinobacteria	S	COGs COG2380 conserved	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6281265_21	1229780.BN381_50029	4.719e-09	66.0	COG2976@1|root,COG2976@2|Bacteria,2GNIS@201174|Actinobacteria,3UXN4@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF4012)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4012
BYD2_k127_6281265_7	1464048.JNZS01000011_gene4891	9.788e-119	400.0	COG1086@1|root,COG2148@1|root,COG1086@2|Bacteria,COG2148@2|Bacteria,2GK0M@201174|Actinobacteria,4D9NF@85008|Micromonosporales	201174|Actinobacteria	M	Sugar transferases involved in lipopolysaccharide synthesis	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
BYD2_k127_6281265_6	1229780.BN381_210100	2.705e-120	391.0	COG1028@1|root,COG1028@2|Bacteria,2GNUM@201174|Actinobacteria,3UX17@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_6281265_14	953739.SVEN_0880	3.037e-55	201.0	COG1476@1|root,COG1917@1|root,COG1476@2|Bacteria,COG1917@2|Bacteria,2I37J@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3,HTH_31
BYD2_k127_6281265_15	469371.Tbis_1787	2.261e-54	212.0	COG0697@1|root,COG0697@2|Bacteria,2GM50@201174|Actinobacteria,4EF86@85010|Pseudonocardiales	201174|Actinobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
BYD2_k127_6281265_8	101510.RHA1_ro01884	2.265e-91	308.0	COG0300@1|root,COG0300@2|Bacteria,2I9IM@201174|Actinobacteria,4FY3P@85025|Nocardiaceae	201174|Actinobacteria	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	Abhydrolase_6,adh_short
BYD2_k127_6281265_10	1380390.JIAT01000011_gene2478	3.065e-83	282.0	COG1018@1|root,COG1018@2|Bacteria,2I28S@201174|Actinobacteria,4CPW9@84995|Rubrobacteria	84995|Rubrobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
BYD2_k127_6281265_18	103733.JNYO01000020_gene1929	3.435e-21	101.0	2E4G6@1|root,32ZBB@2|Bacteria,2GR6E@201174|Actinobacteria,4E7S2@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6281265_1	1229780.BN381_210099	2.432e-191	610.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria,3UX6P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
BYD2_k127_6281265_3	1229780.BN381_210099	3.18e-170	555.0	COG0145@1|root,COG0146@1|root,COG0145@2|Bacteria,COG0146@2|Bacteria,2GIYE@201174|Actinobacteria,3UX6P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EQ	Hydantoinase/oxoprolinase	-	-	3.5.2.14	ko:K01473	ko00330,ko01100,map00330,map01100	-	R03187	RC00632	ko00000,ko00001,ko01000	-	-	-	Hydant_A_N,Hydantoinase_A,Hydantoinase_B
BYD2_k127_6281265_12	397278.JOJN01000002_gene644	7.016e-66	228.0	COG0328@1|root,COG0328@2|Bacteria,2GK53@201174|Actinobacteria,4DR5Z@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhA	GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DUF4440,RNase_H
BYD2_k127_6281265_0	1122182.KB903817_gene1852	0.0	1107.0	COG2609@1|root,COG2609@2|Bacteria,2GJRE@201174|Actinobacteria,4DABZ@85008|Micromonosporales	201174|Actinobacteria	C	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)	aceE	GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0004739,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016624,GO:0016903,GO:0030312,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0045254,GO:0046872,GO:0055114,GO:0071944,GO:1902494,GO:1990204	1.2.4.1	ko:K00163	ko00010,ko00020,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map01100,map01110,map01120,map01130,map01200	M00307	R00014,R00209,R01699,R03270	RC00004,RC00027,RC00627,RC02742,RC02744,RC02882	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
BYD2_k127_6281265_9	1048339.KB913029_gene2615	4.396e-84	295.0	COG0671@1|root,COG1597@1|root,COG0671@2|Bacteria,COG1597@2|Bacteria,2GM2U@201174|Actinobacteria,4ES4W@85013|Frankiales	201174|Actinobacteria	I	Acid phosphatase homologues	bmrU	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DAGK_cat,PAP2
BYD2_k127_6281265_13	227882.SAV_4172	4.659e-59	228.0	COG0177@1|root,COG0177@2|Bacteria,2GNE5@201174|Actinobacteria	201174|Actinobacteria	L	PFAM HhH-GPD family protein	-	-	-	-	-	-	-	-	-	-	-	-	HhH-GPD
BYD2_k127_6281265_17	1150599.MPHLEI_17105	1.056e-28	131.0	COG2852@1|root,COG2852@2|Bacteria,2GKCY@201174|Actinobacteria,236GB@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF559)	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4,DUF559
BYD2_k127_6281265_11	1229780.BN381_210096	4.459e-75	266.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	ycjY	GO:0008150,GO:0009987,GO:0051301	-	ko:K01990,ko:K06889	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	DLH,Hydrolase_4,Peptidase_S15
BYD2_k127_6281265_4	1122611.KB903962_gene4512	7.11e-145	481.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4EG83@85012|Streptosporangiales	201174|Actinobacteria	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
BYD2_k127_6281265_2	1229780.BN381_130069	5.645e-177	591.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,3UX2M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K02021,ko:K06147,ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.110,3.A.1.112,3.A.1.113,3.A.1.117,3.A.1.21,3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_membrane,ABC_tran
BYD2_k127_6281265_20	1313172.YM304_30510	1.376e-13	81.0	296C4@1|root,2ZTMX@2|Bacteria,2HB9V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6281265_5	469383.Cwoe_0403	5.43e-136	488.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,GerE
BYD2_k127_6281265_23	1463858.JOHR01000001_gene6345	1.283e-06	58.0	COG0644@1|root,COG0644@2|Bacteria,2I301@201174|Actinobacteria	201174|Actinobacteria	C	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3,FAD_oxidored
BYD2_k127_6281265_16	1283283.ATXA01000003_gene1646	4.167e-39	161.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria,4EVJY@85013|Frankiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_6281265_22	935839.JAGJ01000009_gene560	5.663e-09	66.0	COG5343@1|root,COG5343@2|Bacteria,2IM7X@201174|Actinobacteria	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
BYD2_k127_6284765_1	1380390.JIAT01000009_gene2156	7.954e-32	130.0	COG3795@1|root,COG3795@2|Bacteria,2IMHE@201174|Actinobacteria,4CTAU@84995|Rubrobacteria	84995|Rubrobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_6284765_0	469383.Cwoe_2628	5.256e-128	423.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_6296917_3	644283.Micau_4226	2.118e-78	280.0	COG0566@1|root,COG0566@2|Bacteria,2GJ12@201174|Actinobacteria,4DAKP@85008|Micromonosporales	201174|Actinobacteria	J	tRNA rRNA methyltransferase	spoU2	-	-	-	-	-	-	-	-	-	-	-	SpoU_methylase
BYD2_k127_6296917_5	1050202.KB913024_gene3617	7.346e-19	94.0	COG3409@1|root,COG3409@2|Bacteria,2GYAB@201174|Actinobacteria,40ACE@622450|Actinopolysporales	201174|Actinobacteria	M	Putative peptidoglycan binding domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1
BYD2_k127_6296917_0	29306.JOBE01000020_gene769	7.303e-250	784.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3,Urease_alpha
BYD2_k127_6296917_1	1907.SGLAU_02090	2.315e-139	462.0	COG1473@1|root,COG1473@2|Bacteria,2GK05@201174|Actinobacteria	201174|Actinobacteria	M	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
BYD2_k127_6296917_4	44060.JODL01000023_gene4965	1.623e-39	153.0	COG2072@1|root,COG3832@1|root,COG2072@2|Bacteria,COG3832@2|Bacteria,2GMDH@201174|Actinobacteria	201174|Actinobacteria	P	flavoprotein involved in K transport	-	-	-	-	-	-	-	-	-	-	-	-	FMO-like,K_oxygenase
BYD2_k127_6296917_2	1313172.YM304_30640	5.469e-112	369.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.3	ko:K00128	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_6313580_7	1408428.JNJP01000005_gene15	2.463e-33	137.0	COG1683@1|root,COG1683@2|Bacteria,1RHER@1224|Proteobacteria,42TQ2@68525|delta/epsilon subdivisions,2WQ1D@28221|Deltaproteobacteria,2MC97@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	Protein of unknown function (DUF523)	-	-	-	-	-	-	-	-	-	-	-	-	DUF523
BYD2_k127_6313580_3	1229780.BN381_100019	2.005e-87	304.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_6313580_9	1229780.BN381_330122	1.142e-23	117.0	COG1051@1|root,COG1051@2|Bacteria,2ISCR@201174|Actinobacteria	201174|Actinobacteria	F	Belongs to the Nudix hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
BYD2_k127_6313580_5	1229780.BN381_330121	1.152e-59	215.0	COG0483@1|root,COG0483@2|Bacteria	2|Bacteria	G	inositol monophosphate 1-phosphatase activity	-	-	3.1.3.25,3.1.3.7	ko:K01082,ko:K01092	ko00521,ko00562,ko00920,ko01100,ko01120,ko01130,ko04070,map00521,map00562,map00920,map01100,map01120,map01130,map04070	M00131	R00188,R00508,R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	Inositol_P
BYD2_k127_6313580_6	1298867.AUES01000032_gene2003	8.488e-59	218.0	COG2030@1|root,COG2030@2|Bacteria,1NYEM@1224|Proteobacteria,2U0F4@28211|Alphaproteobacteria,3JVIY@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	I	dehydratase	MA20_27475	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6313580_2	1214101.BN159_0866	8.858e-119	390.0	COG2220@1|root,COG2220@2|Bacteria,2GMTR@201174|Actinobacteria	201174|Actinobacteria	E	Zn-dependent hydrolases of the beta-lactamase fold	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B_2,Lactamase_B_3
BYD2_k127_6313580_0	469383.Cwoe_2475	7.876e-136	436.0	COG2267@1|root,COG2267@2|Bacteria,2GISG@201174|Actinobacteria,4CS4R@84995|Rubrobacteria	84995|Rubrobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_6313580_8	66897.DJ64_01640	8.577e-27	120.0	COG3415@1|root,COG3415@2|Bacteria,2HK0D@201174|Actinobacteria	201174|Actinobacteria	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,Terminase_5
BYD2_k127_6313580_1	1229780.BN381_330111	1.988e-128	426.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_6313580_10	1229780.BN381_330110	2.673e-14	83.0	COG0358@1|root,COG0358@2|Bacteria,2GJFX@201174|Actinobacteria,3UWAA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB_bind,DnaG_DnaB_bind,Toprim_4,Toprim_N,zf-CHC2
BYD2_k127_6411118_5	1229780.BN381_80303	7.228e-66	239.0	COG0621@1|root,COG0621@2|Bacteria,2GKRI@201174|Actinobacteria,3UX86@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,UPF0004
BYD2_k127_6411118_7	67356.KL575603_gene6777	2.495e-06	62.0	2E61P@1|root,330QX@2|Bacteria,2II66@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6411118_6	1306174.JODP01000010_gene6979	9.851e-49	179.0	COG1595@1|root,COG1595@2|Bacteria,2GJUI@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4
BYD2_k127_6411118_0	1048339.KB913029_gene2528	2.412e-178	599.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_6411118_2	1380393.JHVP01000004_gene617	1.414e-107	354.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4ES91@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_6411118_3	996637.SGM_0953	1.873e-75	278.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_6411118_4	996637.SGM_4294	1.016e-72	264.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
BYD2_k127_6411118_1	1313172.YM304_16440	1.501e-150	485.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,4CMSW@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
BYD2_k127_6474476_0	1043493.BBLU01000004_gene2701	4.367e-98	329.0	COG4221@1|root,COG4221@2|Bacteria,2GMGQ@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the short-chain dehydrogenases reductases (SDR) family	sdh	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	1.1.1.381	ko:K16066	ko00240,ko00260,ko01100,map00240,map00260,map01100	-	R09289,R10851,R10852	RC00087,RC00525,RC03288	ko00000,ko00001,ko01000	-	-	-	adh_short
BYD2_k127_6474476_3	543632.JOJL01000017_gene9894	4.367e-19	98.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4DA14@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
BYD2_k127_6474476_2	1122138.AQUZ01000019_gene8158	1.149e-25	124.0	COG0530@1|root,COG0530@2|Bacteria,2GJR3@201174|Actinobacteria,4DUB5@85009|Propionibacteriales	201174|Actinobacteria	P	Sodium/calcium exchanger protein	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
BYD2_k127_6474476_1	1229780.BN381_80302	3.269e-71	267.0	COG1674@1|root,COG1674@2|Bacteria,2GK3T@201174|Actinobacteria,3UW6P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	D	Ftsk_gamma	-	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
BYD2_k127_6475746_0	1957.JODX01000006_gene3939	2.259e-166	530.0	COG4251@1|root,COG4251@2|Bacteria,2I2KA@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K18351	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_6475746_1	1172181.KB911737_gene1916	1.357e-129	415.0	COG0745@1|root,COG0745@2|Bacteria,2GKYV@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K18352	ko01502,ko02020,map01502,map02020	M00651,M00658	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_6475746_3	1452535.JARD01000009_gene1404	4.456e-12	70.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4FRIV@85023|Microbacteriaceae	201174|Actinobacteria	M	Alanine racemase, C-terminal domain	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
BYD2_k127_6475746_2	469383.Cwoe_1418	5.524e-64	227.0	COG1876@1|root,COG1876@2|Bacteria,2IHUG@201174|Actinobacteria,4CQJR@84995|Rubrobacteria	84995|Rubrobacteria	M	D-alanyl-D-alanine carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	VanY
BYD2_k127_6481574_0	935839.JAGJ01000005_gene2691	1.09e-188	600.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4F52F@85017|Promicromonosporaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	ko:K04753	-	-	-	-	ko00000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
BYD2_k127_6496175_12	1121877.JQKF01000040_gene1861	4.412e-75	259.0	COG2890@1|root,COG2890@2|Bacteria,2GNC1@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the protein N5-glutamine methyltransferase family	-	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS
BYD2_k127_6496175_1	324602.Caur_0149	2.129e-181	587.0	COG0531@1|root,COG0531@2|Bacteria,2G5ZF@200795|Chloroflexi,37597@32061|Chloroflexia	32061|Chloroflexia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
BYD2_k127_6496175_14	653045.Strvi_2189	2.544e-66	236.0	COG0569@1|root,COG0569@2|Bacteria,2GK4N@201174|Actinobacteria	201174|Actinobacteria	P	PFAM TrkA-N domain protein	ceoB	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
BYD2_k127_6496175_13	525909.Afer_1924	4.444e-73	254.0	COG0569@1|root,COG0569@2|Bacteria,2HH1S@201174|Actinobacteria,4CP21@84992|Acidimicrobiia	84992|Acidimicrobiia	C	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
BYD2_k127_6496175_21	1223523.H340_21481	1.322e-14	83.0	COG1200@1|root,COG1200@2|Bacteria,2IHRX@201174|Actinobacteria	201174|Actinobacteria	KL	Nucleic acid binding, OB-fold, tRNA	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6496175_16	1386089.N865_13620	1.815e-59	236.0	29RUH@1|root,30CYE@2|Bacteria,2HHM4@201174|Actinobacteria,4FG38@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6496175_9	710111.FraQA3DRAFT_0001	3.279e-92	331.0	COG3325@1|root,COG3325@2|Bacteria,2IGIW@201174|Actinobacteria,4EVF4@85013|Frankiales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 18 family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6496175_5	1246995.AFR_31390	2.766e-130	428.0	COG0025@1|root,COG0025@2|Bacteria,2GKCK@201174|Actinobacteria,4DAWY@85008|Micromonosporales	201174|Actinobacteria	P	Sodium/hydrogen exchanger family	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
BYD2_k127_6496175_7	1313172.YM304_27120	2.358e-101	338.0	COG0667@1|root,COG0667@2|Bacteria,2ICY2@201174|Actinobacteria,4CNT7@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
BYD2_k127_6496175_22	1348663.KCH_02640	1.484e-05	53.0	COG1366@1|root,COG1366@2|Bacteria,2GUQ0@201174|Actinobacteria,2M3X8@2063|Kitasatospora	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
BYD2_k127_6496175_18	469383.Cwoe_3147	4.194e-48	181.0	COG2203@1|root,COG2203@2|Bacteria,2IQAM@201174|Actinobacteria	201174|Actinobacteria	T	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
BYD2_k127_6496175_11	1121877.JQKF01000048_gene761	1.587e-82	282.0	COG2203@1|root,COG2203@2|Bacteria,2GQ2V@201174|Actinobacteria,4CNWF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	ANTAR	-	-	-	-	-	-	-	-	-	-	-	-	ANTAR,GAF_2
BYD2_k127_6496175_15	306281.AJLK01000102_gene3414	5.702e-63	230.0	COG0604@1|root,COG0604@2|Bacteria,1G3UU@1117|Cyanobacteria,1JK4N@1189|Stigonemataceae	1117|Cyanobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_6496175_8	882083.SacmaDRAFT_5654	3.378e-101	338.0	COG1024@1|root,COG1024@2|Bacteria,2GN3P@201174|Actinobacteria,4E5P5@85010|Pseudonocardiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_6496175_0	405948.SACE_3319	2.893e-197	644.0	COG2141@1|root,COG2141@2|Bacteria,2GKCU@201174|Actinobacteria,4DYKX@85010|Pseudonocardiales	201174|Actinobacteria	C	luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_6496175_3	164757.Mjls_0414	1.454e-165	538.0	COG2197@1|root,COG2197@2|Bacteria,2GKXJ@201174|Actinobacteria,233VG@1762|Mycobacteriaceae	201174|Actinobacteria	K	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BYD2_k127_6496175_6	298655.KI912266_gene4387	3.771e-107	353.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	ko:K03088,ko:K07110	-	-	-	-	ko00000,ko03000,ko03021	-	-	-	HTH_19,HTH_3,HTH_31,Peptidase_M78
BYD2_k127_6496175_17	298655.KI912266_gene4388	4.68e-54	197.0	COG2128@1|root,COG2128@2|Bacteria	2|Bacteria	S	hydroperoxide reductase activity	mip	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_6496175_19	1297569.MESS2_1000038	4.81e-44	171.0	COG0500@1|root,COG2226@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
BYD2_k127_6496175_10	266779.Meso_2458	5.999e-86	307.0	COG0500@1|root,COG2267@1|root,COG2226@2|Bacteria,COG2267@2|Bacteria,1NWX3@1224|Proteobacteria,2TURQ@28211|Alphaproteobacteria,43PQD@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Ubie_methyltran
BYD2_k127_6496175_2	1229780.BN381_10316	3.61e-168	545.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,3UWHF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_6496175_20	1312959.KI914676_gene3327	2.442e-39	159.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
BYD2_k127_6496175_4	1123024.AUII01000019_gene3982	2.093e-139	451.0	COG3266@1|root,COG3266@2|Bacteria,2I44K@201174|Actinobacteria,4DZUJ@85010|Pseudonocardiales	201174|Actinobacteria	S	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6496725_13	1313172.YM304_26900	2.409e-12	68.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
BYD2_k127_6496725_1	1121927.GOHSU_17_00310	8.596e-136	438.0	COG2141@1|root,COG2141@2|Bacteria,2GJ6T@201174|Actinobacteria,4GAMM@85026|Gordoniaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	1.14.14.5	ko:K04091	ko00920,map00920	-	R07210,R10206	RC01779,RC02556	ko00000,ko00001,ko01000	-	-	-	Bac_luciferase
BYD2_k127_6496725_5	208439.AJAP_26440	9.017e-77	281.0	COG0500@1|root,COG2226@2|Bacteria,2I3BB@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_6496725_7	656024.FsymDg_0766	5.57e-55	196.0	COG3576@1|root,COG3576@2|Bacteria,2I3PF@201174|Actinobacteria,4EXBZ@85013|Frankiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
BYD2_k127_6496725_3	1048339.KB913029_gene2112	1.523e-89	329.0	COG4198@1|root,COG4198@2|Bacteria,2GJFV@201174|Actinobacteria,4ESHT@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
BYD2_k127_6496725_8	1313172.YM304_24850	4.548e-54	216.0	COG0647@1|root,COG0647@2|Bacteria,2GK7V@201174|Actinobacteria,4CN5Z@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like
BYD2_k127_6496725_10	1380390.JIAT01000009_gene1569	1.96e-45	185.0	COG0705@1|root,COG0705@2|Bacteria,2GNPK@201174|Actinobacteria,4CR15@84995|Rubrobacteria	84995|Rubrobacteria	S	Rhomboid family	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
BYD2_k127_6496725_6	1313172.YM304_24870	9.425e-65	242.0	COG1189@1|root,COG1189@2|Bacteria,2GJVT@201174|Actinobacteria,4CN67@84992|Acidimicrobiia	84992|Acidimicrobiia	J	FtsJ-like methyltransferase	-	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
BYD2_k127_6496725_4	1313172.YM304_24880	5.85e-77	267.0	COG0061@1|root,COG0061@2|Bacteria,2GKM2@201174|Actinobacteria,4CN3D@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	NAD_kinase
BYD2_k127_6496725_0	1313172.YM304_24890	6.682e-153	501.0	COG0497@1|root,COG0497@2|Bacteria,2GIVG@201174|Actinobacteria,4CMY1@84992|Acidimicrobiia	84992|Acidimicrobiia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	SMC_N
BYD2_k127_6496725_2	1229780.BN381_290087	6.433e-133	438.0	COG4825@1|root,COG4825@2|Bacteria,2GPAA@201174|Actinobacteria,3UXCS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Thiamine pyrophosphokinase C terminal	-	-	-	-	-	-	-	-	-	-	-	-	TPPK_C
BYD2_k127_6496725_11	479432.Sros_5795	3.926e-33	148.0	COG0728@1|root,COG0728@2|Bacteria,2GKN0@201174|Actinobacteria,4EH3I@85012|Streptosporangiales	201174|Actinobacteria	S	Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane	mviN	-	-	ko:K03980	-	-	-	-	ko00000,ko01011,ko02000	2.A.66.4	-	-	MVIN
BYD2_k127_6496725_9	526225.Gobs_3002	1.244e-45	192.0	COG3119@1|root,COG3119@2|Bacteria,2H59R@201174|Actinobacteria,4EURD@85013|Frankiales	201174|Actinobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6496725_14	471852.Tcur_0118	7.94e-10	73.0	COG3119@1|root,COG3119@2|Bacteria,2H59R@201174|Actinobacteria,4EI9V@85012|Streptosporangiales	201174|Actinobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6506498_8	1313172.YM304_36940	1.085e-18	87.0	COG0542@1|root,COG0542@2|Bacteria,2GJ77@201174|Actinobacteria,4CMPF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	C-terminal, D2-small domain, of ClpB protein	-	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
BYD2_k127_6506498_7	1229780.BN381_150077	4.865e-21	105.0	28Z32@1|root,2ZKVK@2|Bacteria,2HCTJ@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6506498_0	211114.JOEF01000003_gene3241	5.262e-129	427.0	COG1066@1|root,COG1066@2|Bacteria,2GMQ0@201174|Actinobacteria,4DZGZ@85010|Pseudonocardiales	201174|Actinobacteria	O	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
BYD2_k127_6506498_1	1229780.BN381_150082	1.929e-124	407.0	COG1623@1|root,COG1623@2|Bacteria,2GJ41@201174|Actinobacteria,3UX2J@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DisA bacterial checkpoint controller nucleotide-binding	disA	-	2.7.7.85	ko:K07067	-	-	-	-	ko00000,ko01000	-	-	-	DisA-linker,DisA_N,HHH,HHH_2
BYD2_k127_6506498_4	1229780.BN381_150083	2.942e-65	229.0	COG0412@1|root,COG0412@2|Bacteria	2|Bacteria	Q	carboxymethylenebutenolidase activity	-	-	3.1.1.45	ko:K01061	ko00361,ko00364,ko00623,ko01100,ko01110,ko01120,ko01130,map00361,map00364,map00623,map01100,map01110,map01120,map01130	-	R03893,R05510,R05511,R06835,R06838,R08120,R08121,R09136,R09220,R09222	RC01018,RC01906,RC01907,RC02441,RC02467,RC02468,RC02674,RC02675,RC02686	ko00000,ko00001,ko01000	-	-	-	DLH
BYD2_k127_6506498_2	1229780.BN381_150086	9.117e-75	270.0	COG0664@1|root,COG0664@2|Bacteria,2GMPN@201174|Actinobacteria,3UWRE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420,ko:K10914,ko:K21561,ko:K21564	ko02020,ko02024,ko02025,ko02026,ko05111,map02020,map02024,map02025,map02026,map05111	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
BYD2_k127_6506498_5	1229780.BN381_150088	1.671e-60	215.0	COG0245@1|root,COG1211@1|root,COG0245@2|Bacteria,COG1211@2|Bacteria,2II8H@201174|Actinobacteria,3UWMP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
BYD2_k127_6506498_6	1313172.YM304_04660	2.713e-57	204.0	COG0245@1|root,COG0245@2|Bacteria,2II8H@201174|Actinobacteria,4CN4V@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
BYD2_k127_6506498_3	1229780.BN381_150089	3.076e-73	264.0	COG0566@1|root,COG0566@2|Bacteria,2GJMR@201174|Actinobacteria,3UWDZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	-	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
BYD2_k127_6506498_9	397278.JOJN01000006_gene1053	2.941e-15	89.0	2CUM0@1|root,32SVJ@2|Bacteria,2IQG7@201174|Actinobacteria,4DRWZ@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF3263)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3263
BYD2_k127_6506847_2	1313172.YM304_26900	1.953e-95	342.0	COG1013@1|root,COG1013@2|Bacteria,2GMI5@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korB	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
BYD2_k127_6506847_0	68199.JNZO01000012_gene3388	1.818e-274	857.0	COG0674@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1014@2|Bacteria,2GKXV@201174|Actinobacteria	201174|Actinobacteria	C	Ferredoxin oxidoreductase	korA	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR,POR_N
BYD2_k127_6506847_1	1172180.KB911792_gene3677	1.964e-179	567.0	COG1830@1|root,COG1830@2|Bacteria,2I9V1@201174|Actinobacteria	201174|Actinobacteria	G	PFAM deoxyribose-phosphate aldolase phospho-2- dehydro-3-deoxyheptonate aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
BYD2_k127_6506847_3	1229780.BN381_290093	4.463e-63	224.0	COG0457@1|root,COG0457@2|Bacteria	1229780.BN381_290093|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6517480_9	66373.JOFQ01000001_gene1902	4.626e-05	46.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	lipP	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_6517480_5	1137271.AZUM01000002_gene2845	2.221e-49	181.0	COG0288@1|root,COG0288@2|Bacteria,2GM1M@201174|Actinobacteria,4E2VK@85010|Pseudonocardiales	201174|Actinobacteria	P	Reversible hydration of carbon dioxide	can	-	4.2.1.1	ko:K01673	ko00910,map00910	-	R00132,R10092	RC02807	ko00000,ko00001,ko01000	-	-	-	Pro_CA
BYD2_k127_6517480_1	1122611.KB903963_gene4892	1.07e-98	330.0	COG3186@1|root,COG3186@2|Bacteria,2GKCB@201174|Actinobacteria,4EIH7@85012|Streptosporangiales	201174|Actinobacteria	E	Biopterin-dependent aromatic amino acid hydroxylase	phhA	-	1.14.16.1	ko:K00500	ko00360,ko00400,ko00790,ko01100,ko01230,map00360,map00400,map00790,map01100,map01230	-	R01795,R07211	RC00490	ko00000,ko00001,ko01000	-	-	-	Biopterin_H
BYD2_k127_6517480_7	1236902.ANAS01000009_gene2483	1.642e-37	147.0	COG1522@1|root,COG1522@2|Bacteria,2HVG9@201174|Actinobacteria,4EK3U@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
BYD2_k127_6517480_6	1463825.JNXC01000003_gene3747	6.949e-48	180.0	COG2340@1|root,COG2340@2|Bacteria,2GM57@201174|Actinobacteria,4E4HQ@85010|Pseudonocardiales	201174|Actinobacteria	S	protein with SCP PR1 domains	-	-	-	-	-	-	-	-	-	-	-	-	CAP
BYD2_k127_6517480_0	1267534.KB906755_gene4189	5.013e-209	684.0	COG0022@1|root,COG1071@1|root,COG0022@2|Bacteria,COG1071@2|Bacteria,3Y34Y@57723|Acidobacteria,2JHQ9@204432|Acidobacteriia	204432|Acidobacteriia	C	Dehydrogenase E1 component	-	-	1.2.4.4	ko:K11381	ko00280,ko00640,ko01100,ko01110,ko01130,map00280,map00640,map01100,map01110,map01130	M00036	R07599,R07600,R07601,R07602,R07603,R07604,R10996,R10997	RC00027,RC00627,RC02743,RC02883,RC02949,RC02953	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	E1_dh,Transket_pyr,Transketolase_C
BYD2_k127_6517480_4	1120936.KB907210_gene5652	6.64e-51	202.0	COG2207@1|root,COG2207@2|Bacteria,2GWDZ@201174|Actinobacteria,4EJI4@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_6517480_2	1121926.AXWO01000008_gene2887	6.114e-88	316.0	COG3612@1|root,COG3612@2|Bacteria,2GN7K@201174|Actinobacteria,4EYC1@85014|Glycomycetales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6517480_3	656024.FsymDg_4173	3.667e-51	208.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_6517480_8	266265.Bxe_A4277	1.855e-24	104.0	COG1703@1|root,COG1884@1|root,COG2185@1|root,COG1703@2|Bacteria,COG1884@2|Bacteria,COG2185@2|Bacteria,1MUXX@1224|Proteobacteria,2VH05@28216|Betaproteobacteria,1K4Q5@119060|Burkholderiaceae	28216|Betaproteobacteria	EI	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly	icmF	GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564	5.4.99.13	ko:K11942	-	-	-	-	ko00000,ko01000	-	-	-	ArgK,B12-binding,MM_CoA_mutase
BYD2_k127_652760_3	882082.SaccyDRAFT_3476	8.213e-22	106.0	COG0673@1|root,COG0673@2|Bacteria,2IGWQ@201174|Actinobacteria,4EBPJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
BYD2_k127_652760_0	1229780.BN381_150046	5.213e-246	766.0	COG0604@1|root,COG0604@2|Bacteria,2GKFF@201174|Actinobacteria,3UX3B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Alcohol dehydrogenase GroES-like domain	ccrA	-	1.3.1.86	ko:K17829	ko00650,ko01120,ko01130,ko01200,map00650,map01120,map01130,map01200	-	R09738	RC00076	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_652760_1	1229780.BN381_150119	2.07e-163	545.0	COG0421@1|root,COG0421@2|Bacteria	2|Bacteria	E	spermidine synthase activity	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
BYD2_k127_652760_2	1229780.BN381_150043	5.744e-79	268.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWCM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA4	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_6534503_0	469383.Cwoe_5435	3.121e-236	748.0	COG0465@1|root,COG0465@2|Bacteria,2H5KC@201174|Actinobacteria	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
BYD2_k127_6534503_7	33898.JRHJ01000038_gene4398	5.524e-16	92.0	2FHIX@1|root,349CW@2|Bacteria,2GN7H@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6534503_2	1146883.BLASA_1739	1.744e-182	594.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria	2|Bacteria	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	-	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilizers,PPDK_N
BYD2_k127_6534503_5	795797.C497_02127	1.873e-81	285.0	COG4292@1|root,arCOG10808@2157|Archaea,2Y30E@28890|Euryarchaeota,23YZX@183963|Halobacteria	183963|Halobacteria	S	Low temperature requirement protein A	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
BYD2_k127_6534503_1	1313172.YM304_12820	2.817e-185	590.0	COG0624@1|root,COG0624@2|Bacteria,2GM84@201174|Actinobacteria,4CMU6@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
BYD2_k127_6534503_3	1123319.AUBE01000002_gene1156	1.171e-106	361.0	COG0053@1|root,COG0053@2|Bacteria,2GKSG@201174|Actinobacteria	201174|Actinobacteria	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
BYD2_k127_6534503_6	1120948.KB903219_gene657	8.333e-28	119.0	COG1396@1|root,COG1396@2|Bacteria,2GPQW@201174|Actinobacteria,4EC3K@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BYD2_k127_6534503_4	438753.AZC_0383	1.205e-102	338.0	COG0450@1|root,COG0450@2|Bacteria,1MX2B@1224|Proteobacteria,2TT09@28211|Alphaproteobacteria,3EYMY@335928|Xanthobacteraceae	28211|Alphaproteobacteria	O	PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen	-	-	-	-	-	-	-	-	-	-	-	-	1-cysPrx_C,AhpC-TSA
BYD2_k127_6539157_4	1504319.GM45_0705	7.675e-61	220.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,3UWMS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
BYD2_k127_6539157_0	1435356.Y013_04375	3.734e-225	728.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4FV1E@85025|Nocardiaceae	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	ctaD	GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0098655,GO:0098660,GO:0098662,GO:1902600	1.9.3.1	ko:K02274	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1
BYD2_k127_6539157_6	378753.KRH_12840	5.907e-05	53.0	2D9MJ@1|root,32TTI@2|Bacteria,2IFFM@201174|Actinobacteria,1WCPH@1268|Micrococcaceae	201174|Actinobacteria	C	Belongs to the cytochrome c oxidase bacterial subunit CtaF family	ctaF	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Cyt_c_ox_IV
BYD2_k127_6539157_2	35754.JNYJ01000037_gene4695	2.239e-148	489.0	COG1741@1|root,COG1741@2|Bacteria,2GIY9@201174|Actinobacteria,4D9FR@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
BYD2_k127_6539157_1	402881.Plav_2680	1.113e-216	687.0	COG3653@1|root,COG3653@2|Bacteria,1MWWY@1224|Proteobacteria,2TSZZ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	COG3653 N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
BYD2_k127_6539157_3	47763.JNZA01000033_gene3075	3.496e-137	472.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,Trans_reg_C
BYD2_k127_6572645_4	1133849.O3I_013150	4.286e-37	147.0	COG2018@1|root,COG2018@2|Bacteria,2IFP1@201174|Actinobacteria,4G0P4@85025|Nocardiaceae	201174|Actinobacteria	S	Roadblock/LC7 domain	-	-	-	ko:K07131	-	-	-	-	ko00000	-	-	-	Robl_LC7
BYD2_k127_6572645_1	1306990.BARG01000099_gene9426	1.392e-82	303.0	COG0642@1|root,COG2205@2|Bacteria,2I2WT@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,NIT
BYD2_k127_6572645_0	526225.Gobs_4444	1.165e-109	379.0	COG5305@1|root,COG5305@2|Bacteria,2HTG8@201174|Actinobacteria,4ESH8@85013|Frankiales	201174|Actinobacteria	S	Dolichyl-phosphate-mannose-protein mannosyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
BYD2_k127_6572645_3	1229780.BN381_50112	5.571e-65	226.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
BYD2_k127_6572645_2	656024.FsymDg_1995	1.815e-66	230.0	COG1232@1|root,COG1232@2|Bacteria,2IDI5@201174|Actinobacteria,4ETUQ@85013|Frankiales	201174|Actinobacteria	H	PFAM amine oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
BYD2_k127_6599802_1	216594.MMAR_1373	7.64e-114	377.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,233GJ@1762|Mycobacteriaceae	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,rve,rve_3
BYD2_k127_6599802_0	246200.SPO3036	2.207e-318	986.0	COG2015@1|root,COG2015@2|Bacteria,1MU82@1224|Proteobacteria,2TSM1@28211|Alphaproteobacteria,4ND2Q@97050|Ruegeria	28211|Alphaproteobacteria	Q	Alkyl sulfatase dimerisation	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
BYD2_k127_6599802_9	585531.HMPREF0063_12509	6.348e-07	61.0	COG1309@1|root,COG1309@2|Bacteria,2IGXP@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K22295	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
BYD2_k127_6599802_5	710686.Mycsm_01705	5.951e-19	100.0	COG1309@1|root,COG1309@2|Bacteria,2IGXP@201174|Actinobacteria,238UJ@1762|Mycobacteriaceae	201174|Actinobacteria	K	transcriptional	-	GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141	-	ko:K22295	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
BYD2_k127_6599802_8	522306.CAP2UW1_1998	2.817e-09	64.0	29VND@1|root,30H5P@2|Bacteria,1RBVN@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6599802_10	1035308.AQYY01000001_gene3456	1.554e-05	55.0	COG3965@1|root,COG3965@2|Bacteria,1UZ78@1239|Firmicutes,24BM7@186801|Clostridia	186801|Clostridia	P	cation diffusion facilitator family transporter	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux
BYD2_k127_6599802_6	1380356.JNIK01000002_gene4795	8.774e-17	87.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
BYD2_k127_6599802_4	449673.BACSTE_00445	2.752e-23	111.0	COG2961@1|root,COG2961@2|Bacteria,4PJCP@976|Bacteroidetes,2FREI@200643|Bacteroidia,4AKUI@815|Bacteroidaceae	976|Bacteroidetes	S	COG COG2961 Protein involved in catabolism of external DNA	-	-	2.1.1.266	ko:K07115	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	RsmJ
BYD2_k127_6599802_2	644548.SCNU_12467	4.92e-75	263.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria,4GBT5@85026|Gordoniaceae	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	mprA	GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009268,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010446,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0023052,GO:0030312,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0035556,GO:0043254,GO:0044087,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_6599802_3	469383.Cwoe_1565	1.857e-51	200.0	COG0642@1|root,COG2205@2|Bacteria,2GM17@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07653	ko02020,map02020	M00460	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_6601867_2	1313172.YM304_26380	1.509e-25	107.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CMS1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_6601867_1	1313172.YM304_26370	1.306e-69	252.0	COG0277@1|root,COG0277@2|Bacteria,2H3K3@201174|Actinobacteria,4CNDA@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD binding domain	-	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD_binding_4
BYD2_k127_6601867_0	1313172.YM304_26330	2.468e-125	415.0	COG0247@1|root,COG0247@2|Bacteria,2GIVX@201174|Actinobacteria,4CN2B@84992|Acidimicrobiia	84992|Acidimicrobiia	C	4Fe-4S dicluster domain	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4_7
BYD2_k127_6601867_3	67267.JNXT01000011_gene1047	1.111e-20	97.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_6619189_4	366649.XFF4834R_chr09040	2.713e-51	200.0	COG0642@1|root,COG0784@1|root,COG5278@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,COG5278@2|Bacteria,1NRP8@1224|Proteobacteria,1RRSJ@1236|Gammaproteobacteria,1X3DD@135614|Xanthomonadales	135614|Xanthomonadales	T	CHASE3 domain	torS	-	-	-	-	-	-	-	-	-	-	-	CHASE3,HATPase_c,HisKA,Response_reg
BYD2_k127_6619189_2	1150399.AQYK01000001_gene1524	2.923e-70	251.0	COG2120@1|root,COG2204@1|root,COG2120@2|Bacteria,COG2204@2|Bacteria,2IC4R@201174|Actinobacteria,4FPP2@85023|Microbacteriaceae	201174|Actinobacteria	T	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L,Response_reg
BYD2_k127_6619189_0	1229780.BN381_250102	1.07e-217	679.0	COG1960@1|root,COG1960@2|Bacteria,2GIX8@201174|Actinobacteria,3UX7N@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_6619189_1	929712.KI912613_gene4125	7.318e-91	309.0	COG2141@1|root,COG2141@2|Bacteria,2ID60@201174|Actinobacteria,4CTIG@84995|Rubrobacteria	84995|Rubrobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_6619189_3	1112204.GPOL_c33980	3.065e-67	253.0	COG2375@1|root,COG2375@2|Bacteria,2GK5X@201174|Actinobacteria,4GGZB@85026|Gordoniaceae	201174|Actinobacteria	P	Siderophore-interacting protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_9,SIP
BYD2_k127_6619189_5	1137269.AZWL01000055_gene1294	6.412e-32	136.0	2EHMT@1|root,33BDH@2|Bacteria,2H2DJ@201174|Actinobacteria	201174|Actinobacteria	S	Alternative oxidase	-	-	-	-	-	-	-	-	-	-	-	-	AOX
BYD2_k127_6619189_6	1382356.JQMP01000003_gene2449	8.964e-09	59.0	COG4454@1|root,COG4454@2|Bacteria,2GA6H@200795|Chloroflexi,27YMB@189775|Thermomicrobia	189775|Thermomicrobia	P	Copper binding proteins, plastocyanin/azurin family	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
BYD2_k127_6621448_2	1229780.BN381_310008	1.536e-131	436.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_6621448_0	298654.FraEuI1c_1929	4.77e-198	639.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	aldA_1	-	1.2.1.3,1.2.1.39	ko:K00128,ko:K00146	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00360,ko00380,ko00410,ko00561,ko00620,ko00625,ko00643,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00360,map00380,map00410,map00561,map00620,map00625,map00643,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02536,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
BYD2_k127_6621448_3	1172188.KB911824_gene3194	8.102e-99	338.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4FHS3@85021|Intrasporangiaceae	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
BYD2_k127_6621448_4	1122611.KB903940_gene2047	1.337e-58	222.0	COG0477@1|root,COG2814@2|Bacteria,2I8TX@201174|Actinobacteria,4EMS8@85012|Streptosporangiales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_6621448_1	1123320.KB889662_gene1623	1.535e-188	592.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_6629708_3	1121385.AQXW01000004_gene3283	2.215e-19	104.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,1ZWBP@145357|Dermacoccaceae	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_6629708_2	83332.Rv1189	2.976e-59	234.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria,236KX@1762|Mycobacteriaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	sigI	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_6629708_0	1120936.KB907208_gene981	8.572e-268	858.0	COG1838@1|root,COG1951@1|root,COG1838@2|Bacteria,COG1951@2|Bacteria,2GK6D@201174|Actinobacteria,4EG9D@85012|Streptosporangiales	201174|Actinobacteria	C	Catalyzes the reversible hydration of fumarate to (S)- malate	fum	-	4.2.1.2,4.2.1.32	ko:K01676,ko:K01678,ko:K03780	ko00020,ko00620,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00630,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R00339,R01082	RC00443,RC01382	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase,Fumerase_C
BYD2_k127_6629708_1	1449355.JQNR01000005_gene4003	8.846e-186	620.0	COG0114@1|root,COG0114@2|Bacteria,2GKWY@201174|Actinobacteria	201174|Actinobacteria	C	Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate	fumC	GO:0003674,GO:0003824,GO:0004333,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0071944,GO:0072350	4.2.1.2	ko:K01679	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko04934,ko05200,ko05211,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200,map04934,map05200,map05211	M00009,M00011,M00173,M00376	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	FumaraseC_C,Lyase_1
BYD2_k127_663007_1	330084.JNYZ01000027_gene8101	1.951e-78	268.0	COG3653@1|root,COG3653@2|Bacteria,2I8X9@201174|Actinobacteria,4E2EA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
BYD2_k127_663007_3	882082.SaccyDRAFT_2698	1.984e-26	111.0	COG1846@1|root,COG1846@2|Bacteria,2IMGG@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,HTH_24,MarR_2
BYD2_k127_663007_0	211114.JOEF01000044_gene6120	3.678e-102	345.0	COG4292@1|root,COG4292@2|Bacteria,2GJPB@201174|Actinobacteria,4DXN8@85010|Pseudonocardiales	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
BYD2_k127_663007_2	526225.Gobs_5078	5.307e-65	233.0	COG5549@1|root,COG5549@2|Bacteria,2IPD4@201174|Actinobacteria	201174|Actinobacteria	O	protein import	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M10
BYD2_k127_6634995_4	1125863.JAFN01000001_gene29	2.581e-158	533.0	COG0108@1|root,COG0807@1|root,COG0108@2|Bacteria,COG0807@2|Bacteria,1MU8P@1224|Proteobacteria,42N1C@68525|delta/epsilon subdivisions,2WIP5@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate	ribBA	-	3.5.4.25,4.1.99.12	ko:K14652	ko00740,ko00790,ko01100,ko01110,map00740,map00790,map01100,map01110	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	DHBP_synthase,GTP_cyclohydro2
BYD2_k127_6634995_17	1229780.BN381_50159	1.007e-67	235.0	COG0307@1|root,COG0307@2|Bacteria,2GKC5@201174|Actinobacteria,3UWNT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Lumazine binding domain	ribE	GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.9	ko:K00793	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00066	RC00958,RC00960	ko00000,ko00001,ko00002,ko01000	-	-	-	Lum_binding
BYD2_k127_6634995_7	1229780.BN381_50158	1.625e-123	404.0	COG0117@1|root,COG1985@1|root,COG0117@2|Bacteria,COG1985@2|Bacteria,2GKAX@201174|Actinobacteria,3UWIW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate	ribD	-	1.1.1.193,3.5.4.26	ko:K11752	ko00740,ko01100,ko01110,ko02024,map00740,map01100,map01110,map02024	M00125	R03458,R03459	RC00204,RC00933	ko00000,ko00001,ko00002,ko01000	-	-	-	RibD_C,dCMP_cyt_deam_1
BYD2_k127_6634995_21	1313172.YM304_20590	1.215e-53	196.0	COG0521@1|root,COG0521@2|Bacteria,2II28@201174|Actinobacteria,4CN1Q@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Probable molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
BYD2_k127_6634995_9	1313172.YM304_20580	2.777e-101	356.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,2GM21@201174|Actinobacteria	201174|Actinobacteria	JK	Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family	fmu	GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,NusB
BYD2_k127_6634995_12	1313172.YM304_20570	1.467e-85	299.0	COG0223@1|root,COG0223@2|Bacteria,2GKH5@201174|Actinobacteria,4CN6M@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formyl transferase, C-terminal domain	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
BYD2_k127_6634995_18	1229780.BN381_50154	1.288e-62	233.0	COG0242@1|root,COG0242@2|Bacteria,2GJ87@201174|Actinobacteria,3UWS7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
BYD2_k127_6634995_15	58123.JOFJ01000006_gene322	3.623e-71	247.0	COG2813@1|root,COG2813@2|Bacteria,2IFG7@201174|Actinobacteria,4EFU8@85012|Streptosporangiales	201174|Actinobacteria	J	Putative methyltransferase	rsmC	-	2.1.1.172	ko:K00564	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	MTS
BYD2_k127_6634995_20	1120936.KB907217_gene3498	7.54e-54	205.0	COG0566@1|root,COG0566@2|Bacteria,2IEGA@201174|Actinobacteria,4EGKK@85012|Streptosporangiales	201174|Actinobacteria	J	SpoU rRNA Methylase family	-	-	2.1.1.34	ko:K00556	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
BYD2_k127_6634995_14	68223.JNZY01000031_gene211	1.714e-78	288.0	COG4552@1|root,COG4552@2|Bacteria,2GNXZ@201174|Actinobacteria	201174|Actinobacteria	S	N-acetyltransferase	eis	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
BYD2_k127_6634995_1	103733.JNYO01000007_gene5167	1.087e-204	659.0	COG1028@1|root,COG3347@1|root,COG1028@2|Bacteria,COG3347@2|Bacteria,2GNEI@201174|Actinobacteria,4DX5Z@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Class II Aldolase and Adducin N-terminal domain	srlD	-	1.1.1.140	ko:K00068	ko00051,map00051	-	R05607	RC00085	ko00000,ko00001,ko01000	-	-	-	Aldolase_II,adh_short,adh_short_C2
BYD2_k127_6634995_8	1120934.KB894436_gene4372	1.184e-113	377.0	COG0182@1|root,COG0182@2|Bacteria,2GJJA@201174|Actinobacteria,4DZKT@85010|Pseudonocardiales	201174|Actinobacteria	J	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)	mtnA	-	5.3.1.23	ko:K08963	ko00270,ko01100,map00270,map01100	M00034	R04420	RC01151	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II,IF-2B
BYD2_k127_6634995_25	1385520.N802_02090	1.365e-26	111.0	COG2002@1|root,COG2002@2|Bacteria,2GWND@201174|Actinobacteria	201174|Actinobacteria	K	SpoVT / AbrB like domain	-	-	-	-	-	-	-	-	-	-	-	-	MazE_antitoxin
BYD2_k127_6634995_19	1385520.N802_02095	1.301e-56	199.0	COG1487@1|root,COG1487@2|Bacteria,2INNM@201174|Actinobacteria,4FJ5N@85021|Intrasporangiaceae	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN
BYD2_k127_6634995_11	1229780.BN381_50152	5.882e-94	318.0	COG1198@1|root,COG1198@2|Bacteria,2GKES@201174|Actinobacteria,3UWAF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
BYD2_k127_6634995_22	1313172.YM304_20530	3.212e-47	180.0	COG1198@1|root,COG1198@2|Bacteria,2HG9D@201174|Actinobacteria,4CN7P@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	-	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	-
BYD2_k127_6634995_3	1121946.AUAX01000008_gene7184	8.556e-161	534.0	COG0192@1|root,COG0192@2|Bacteria,2GJ4U@201174|Actinobacteria,4D8EK@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
BYD2_k127_6634995_5	1313172.YM304_20510	2.207e-148	481.0	COG0452@1|root,COG0452@2|Bacteria,2GJGJ@201174|Actinobacteria,4CMYE@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine	coaBC	-	4.1.1.36,6.3.2.5	ko:K13038	ko00770,ko01100,map00770,map01100	M00120	R03269,R04231	RC00064,RC00090,RC00822	ko00000,ko00001,ko00002,ko01000	-	-	-	DFP,Flavoprotein
BYD2_k127_6634995_26	1313172.YM304_20500	1.985e-23	103.0	COG1758@1|root,COG1758@2|Bacteria,2HG9P@201174|Actinobacteria,4CN82@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
BYD2_k127_6634995_24	673860.AciM339_1124	1.609e-34	139.0	COG1102@1|root,arCOG01037@2157|Archaea,2XWPB@28890|Euryarchaeota,3F3AN@33867|unclassified Euryarchaeota	28890|Euryarchaeota	F	Belongs to the cytidylate kinase family. Type 2 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
BYD2_k127_6634995_23	1121877.JQKF01000023_gene2253	5.328e-36	139.0	COG0099@1|root,COG0099@2|Bacteria,2IKPU@201174|Actinobacteria,4CN68@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Helix-hairpin-helix DNA-binding motif class 1	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6634995_16	1229780.BN381_50146	2.262e-70	247.0	COG0284@1|root,COG0284@2|Bacteria,2HPEA@201174|Actinobacteria,3UXRN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Orotidine 5'-phosphate decarboxylase / HUMPS family	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	-	OMPdecase
BYD2_k127_6634995_10	1313172.YM304_20470	1.357e-97	361.0	COG0167@1|root,COG0167@2|Bacteria,2GKC6@201174|Actinobacteria,4CN0R@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
BYD2_k127_6634995_0	1313172.YM304_20460	0.0	1537.0	COG0458@1|root,COG0458@2|Bacteria,2GK5N@201174|Actinobacteria,4CMUA@84992|Acidimicrobiia	84992|Acidimicrobiia	EF	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
BYD2_k127_6634995_6	1313172.YM304_20450	1.713e-147	477.0	COG0505@1|root,COG0505@2|Bacteria,2GKFA@201174|Actinobacteria,4CMXV@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Carbamoyl-phosphate synthase small chain, CPSase domain	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
BYD2_k127_6634995_2	1229780.BN381_50140	6.605e-166	542.0	COG0044@1|root,COG0044@2|Bacteria,2GJ0T@201174|Actinobacteria,3UWBY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
BYD2_k127_6634995_13	351607.Acel_1301	2.552e-79	269.0	COG0540@1|root,COG0540@2|Bacteria,2GKNA@201174|Actinobacteria,4ES0C@85013|Frankiales	201174|Actinobacteria	F	Belongs to the ATCase OTCase family	pyrB	GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
BYD2_k127_664602_4	1313172.YM304_26990	3.348e-62	218.0	COG0436@1|root,COG0436@2|Bacteria,2H440@201174|Actinobacteria,4CMXW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
BYD2_k127_664602_5	1133849.O3I_040545	2.563e-30	134.0	2EQSP@1|root,33ICH@2|Bacteria,2GWX9@201174|Actinobacteria,4G2K3@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_664602_0	500153.JOEK01000014_gene5619	4.165e-134	437.0	COG2171@1|root,COG2171@2|Bacteria,2GIZ9@201174|Actinobacteria	201174|Actinobacteria	E	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA	dapD	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008666,GO:0016020,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0030312,GO:0031402,GO:0031420,GO:0040007,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0048037,GO:0050662,GO:0071944	2.3.1.117	ko:K00674	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R04365	RC00004,RC01136	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1201c	Hexapep_2,THDPS_M
BYD2_k127_664602_1	1229780.BN381_80328	1.164e-128	439.0	COG0624@1|root,COG0624@2|Bacteria,2GK09@201174|Actinobacteria,3UWHI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Peptidase family M28	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
BYD2_k127_664602_2	1313172.YM304_26970	5.014e-88	296.0	COG1974@1|root,COG1974@2|Bacteria,2GMBN@201174|Actinobacteria,4CN5D@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
BYD2_k127_664602_6	1048339.KB913029_gene4758	1.425e-06	57.0	COG1388@1|root,COG1388@2|Bacteria,2GWI9@201174|Actinobacteria,4ETIZ@85013|Frankiales	201174|Actinobacteria	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
BYD2_k127_664602_7	391037.Sare_2967	1.728e-06	59.0	COG3599@1|root,COG3599@2|Bacteria,2H71K@201174|Actinobacteria,4DJIV@85008|Micromonosporales	201174|Actinobacteria	D	regulation of cell shape	-	-	-	-	-	-	-	-	-	-	-	-	DivIVA
BYD2_k127_664602_3	1136417.AZWE01000029_gene226	3.653e-69	242.0	COG0543@1|root,COG1017@1|root,COG0543@2|Bacteria,COG1017@2|Bacteria,2GKXT@201174|Actinobacteria,4D9VT@85008|Micromonosporales	201174|Actinobacteria	C	Belongs to the globin family	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Globin,NAD_binding_1
BYD2_k127_6659718_10	1229780.BN381_330015	7.97e-29	122.0	COG1399@1|root,COG1399@2|Bacteria,2GJTS@201174|Actinobacteria,3UWUU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterized ACR, COG1399	-	GO:0008150,GO:0040007	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
BYD2_k127_6659718_11	1313172.YM304_18640	6.648e-19	93.0	COG0333@1|root,COG0333@2|Bacteria	2|Bacteria	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
BYD2_k127_6659718_3	1313172.YM304_18650	1.009e-113	380.0	COG0416@1|root,COG0416@2|Bacteria,2I8WT@201174|Actinobacteria,4CMRM@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
BYD2_k127_6659718_9	1313172.YM304_18660	6.983e-37	142.0	COG0236@1|root,COG0236@2|Bacteria,2HG9V@201174|Actinobacteria,4CN8D@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
BYD2_k127_6659718_6	1313172.YM304_18670	6.774e-58	213.0	COG0571@1|root,COG0571@2|Bacteria,2GKER@201174|Actinobacteria,4CN7Y@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
BYD2_k127_6659718_8	1313172.YM304_18680	2.508e-52	196.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,4CN5C@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	mutM	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
BYD2_k127_6659718_0	1313172.YM304_18690	0.0	1077.0	COG1196@1|root,COG1196@2|Bacteria,2GK93@201174|Actinobacteria,4CMQE@84992|Acidimicrobiia	84992|Acidimicrobiia	D	RecF/RecN/SMC N terminal domain	-	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N
BYD2_k127_6659718_4	1137269.AZWL01000002_gene6385	7.471e-78	279.0	COG2304@1|root,COG2304@2|Bacteria,2GNKP@201174|Actinobacteria	201174|Actinobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	BatA,VWA_2
BYD2_k127_6659718_5	526225.Gobs_2087	5.513e-74	277.0	COG1721@1|root,COG1721@2|Bacteria,2GKSJ@201174|Actinobacteria,4ES3V@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function DUF58	-	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF58
BYD2_k127_6659718_1	391037.Sare_3254	5.086e-128	427.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4D8TR@85008|Micromonosporales	201174|Actinobacteria	S	ATPase associated with various cellular activities	moxR1	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
BYD2_k127_6659718_2	1229780.BN381_330032	5.89e-119	393.0	COG0552@1|root,COG0552@2|Bacteria,2GJQH@201174|Actinobacteria,3UWGZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
BYD2_k127_6659718_7	345341.KUTG_04341	7.545e-54	196.0	COG1272@1|root,COG1272@2|Bacteria,2GJGQ@201174|Actinobacteria,4DYPN@85010|Pseudonocardiales	201174|Actinobacteria	S	TIGRFAM channel protein, hemolysin III family	hlyI	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
BYD2_k127_6678072_3	1313172.YM304_08910	1.193e-47	180.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CMZ5@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
BYD2_k127_6678072_0	1313172.YM304_08920	3.202e-96	338.0	COG0787@1|root,COG0787@2|Bacteria,2GM2Y@201174|Actinobacteria,4CN11@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
BYD2_k127_6678072_1	446470.Snas_1456	7.266e-77	271.0	COG3191@1|root,COG3191@2|Bacteria,2GJKQ@201174|Actinobacteria,4EYHM@85014|Glycomycetales	201174|Actinobacteria	EQ	Peptidase family S58	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S58
BYD2_k127_6678072_5	1313172.YM304_08930	3.867e-33	145.0	COG0802@1|root,COG0802@2|Bacteria,2IKV2@201174|Actinobacteria,4CNEU@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Threonylcarbamoyl adenosine biosynthesis protein TsaE	-	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
BYD2_k127_6678072_2	1229780.BN381_130031	1.081e-75	268.0	COG1214@1|root,COG1214@2|Bacteria,2GMTM@201174|Actinobacteria,3UWTU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Glycoprotease family	yeaZ	GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Peptidase_M22
BYD2_k127_6678072_4	1313172.YM304_08950	3.296e-42	166.0	COG0454@1|root,COG0456@2|Bacteria,2HGCA@201174|Actinobacteria,4CNAC@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1
BYD2_k127_6692187_1	1283283.ATXA01000010_gene4583	4.585e-06	57.0	COG0457@1|root,COG0457@2|Bacteria	1283283.ATXA01000010_gene4583|-	S	peptidyl-tyrosine sulfation	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6692187_0	1229780.BN381_110049	2.27e-117	384.0	COG1190@1|root,COG1190@2|Bacteria,2GKE0@201174|Actinobacteria,3UW8P@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the class-II aminoacyl-tRNA synthetase family	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
BYD2_k127_6728580_0	298655.KI912267_gene6926	3.943e-197	621.0	COG2159@1|root,COG2159@2|Bacteria,2I9QG@201174|Actinobacteria	201174|Actinobacteria	S	metal-dependent hydrolase of the TIM-barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_6728580_3	1120950.KB892782_gene280	5.426e-88	323.0	COG3416@1|root,COG3416@2|Bacteria,2HVVA@201174|Actinobacteria,4DQRT@85009|Propionibacteriales	201174|Actinobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
BYD2_k127_6728580_2	68194.JNXR01000013_gene5626	4.741e-97	356.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
BYD2_k127_6728580_8	471852.Tcur_1800	0.0002282	50.0	2F62M@1|root,33YKZ@2|Bacteria,2GX5M@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6728580_6	543632.JOJL01000027_gene2801	3.529e-58	207.0	2DMC7@1|root,32J0V@2|Bacteria,2I81N@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF4395)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4395
BYD2_k127_6728580_4	1157634.KB912949_gene2662	1.287e-84	300.0	COG5438@1|root,COG5438@2|Bacteria,2GKJ4@201174|Actinobacteria	201174|Actinobacteria	S	YibE F family protein	-	-	-	-	-	-	-	-	-	-	-	-	YibE_F
BYD2_k127_6728580_7	1137268.AZXF01000005_gene3277	1.461e-42	161.0	COG1188@1|root,COG1188@2|Bacteria,2IQ6F@201174|Actinobacteria,4EK7V@85012|Streptosporangiales	201174|Actinobacteria	J	S4 RNA-binding domain	hslR	-	-	ko:K04762	-	-	-	-	ko00000,ko03110	-	-	-	S4
BYD2_k127_6728580_1	1254432.SCE1572_23945	2.245e-100	345.0	COG2159@1|root,COG2159@2|Bacteria,1PZGI@1224|Proteobacteria,435YS@68525|delta/epsilon subdivisions,2X9TW@28221|Deltaproteobacteria,2Z1SH@29|Myxococcales	28221|Deltaproteobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
BYD2_k127_6728580_5	1313172.YM304_29180	4.124e-78	290.0	COG1624@1|root,COG1624@2|Bacteria	2|Bacteria	S	cAMP biosynthetic process	CP_0674	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N,PTS_EIIA_2
BYD2_k127_6770906_8	47763.JNZA01000022_gene2753	1.593e-09	59.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_6770906_4	471853.Bcav_1789	5.321e-48	179.0	COG1670@1|root,COG1670@2|Bacteria	2|Bacteria	J	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
BYD2_k127_6770906_7	1313172.YM304_34610	1.794e-28	115.0	COG1278@1|root,COG1278@2|Bacteria,2GQRU@201174|Actinobacteria	201174|Actinobacteria	K	Cold shock protein	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
BYD2_k127_6770906_1	477641.MODMU_3261	7.08e-73	263.0	COG3832@1|root,COG3832@2|Bacteria,2IHTJ@201174|Actinobacteria,4ESXN@85013|Frankiales	201174|Actinobacteria	S	Activator of Hsp90 ATPase 1 family protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_6770906_3	477641.MODMU_3260	1.744e-55	196.0	COG0640@1|root,COG0640@2|Bacteria,2IKQY@201174|Actinobacteria,4EVH9@85013|Frankiales	201174|Actinobacteria	K	transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_6770906_0	1123258.AQXZ01000008_gene1318	4.325e-76	272.0	COG1024@1|root,COG1024@2|Bacteria,2GJ63@201174|Actinobacteria,4FXY5@85025|Nocardiaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_6770906_5	1313172.YM304_18580	3.008e-40	166.0	COG0742@1|root,COG0742@2|Bacteria,2GQ3G@201174|Actinobacteria,4CN8I@84992|Acidimicrobiia	84992|Acidimicrobiia	L	Conserved hypothetical protein 95	-	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
BYD2_k127_6770906_2	1229780.BN381_330013	8.424e-67	231.0	COG0669@1|root,COG0669@2|Bacteria,2GN1S@201174|Actinobacteria,3UWQ3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016043,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0022607,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034214,GO:0034641,GO:0034654,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0055086,GO:0065003,GO:0070566,GO:0071704,GO:0071840,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
BYD2_k127_6770906_6	1313172.YM304_18600	3.925e-33	142.0	COG0711@1|root,COG0711@2|Bacteria,2HG9T@201174|Actinobacteria,4CN89@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6782708_1	909613.UO65_3393	1.097e-154	533.0	COG2909@1|root,COG3629@1|root,COG2909@2|Bacteria,COG3629@2|Bacteria,2IBMM@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
BYD2_k127_6782708_0	215803.DB30_8791	7.308e-266	903.0	COG2267@1|root,COG2303@1|root,COG2908@1|root,COG2267@2|Bacteria,COG2303@2|Bacteria,COG2908@2|Bacteria,1QQ8F@1224|Proteobacteria,42PWF@68525|delta/epsilon subdivisions,2WKVA@28221|Deltaproteobacteria,2YYIQ@29|Myxococcales	28221|Deltaproteobacteria	E	GMC oxidoreductase	choD	-	1.1.3.6	ko:K03333	ko00984,ko01120,map00984,map01120	-	R01459	RC00146	ko00000,ko00001,ko01000	-	-	-	GMC_oxred_C,GMC_oxred_N
BYD2_k127_6825979_4	1229780.BN381_80129	3.238e-29	120.0	COG0111@1|root,COG0111@2|Bacteria,2GJGA@201174|Actinobacteria,3UWCG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	serA	GO:0003674,GO:0003824,GO:0004617,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030312,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C,ACT
BYD2_k127_6825979_0	1229780.BN381_450030	3.972e-253	796.0	COG0119@1|root,COG0119@2|Bacteria,2GISX@201174|Actinobacteria,3UW8G@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
BYD2_k127_6825979_1	649831.L083_1021	7.385e-111	385.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4D90U@85008|Micromonosporales	201174|Actinobacteria	E	Peptidase M1 membrane alanine aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
BYD2_k127_6825979_5	1345697.M493_17985	2.58e-11	72.0	COG1366@1|root,COG1366@2|Bacteria,1VJ5S@1239|Firmicutes,4HQMG@91061|Bacilli,1WGKS@129337|Geobacillus	91061|Bacilli	T	STAS domain	rsbV	-	-	ko:K04749	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
BYD2_k127_6825979_3	298655.KI912266_gene2056	1.971e-56	213.0	COG1191@1|root,COG1191@2|Bacteria,2GKSY@201174|Actinobacteria,4ES7X@85013|Frankiales	201174|Actinobacteria	K	RNA polymerase	sigF	GO:0000988,GO:0000990,GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0006629,GO:0006950,GO:0006979,GO:0006995,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009409,GO:0009605,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016987,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034059,GO:0036293,GO:0042221,GO:0042594,GO:0043175,GO:0043254,GO:0043562,GO:0044087,GO:0044238,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0070417,GO:0070482,GO:0071496,GO:0071704,GO:0080090,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2000142,GO:2001141	-	ko:K03090	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_6825979_6	1536772.R70723_28505	1.88e-07	58.0	COG2172@1|root,COG2172@2|Bacteria,1V1IA@1239|Firmicutes,4HFPF@91061|Bacilli,26XWB@186822|Paenibacillaceae	91061|Bacilli	T	Binds to sigma-B preventing the formation of an RNA polymerase holoenzyme	rsbW	GO:0000988,GO:0000989,GO:0003674,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141	2.7.11.1	ko:K04757	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c_2
BYD2_k127_6825979_2	1229780.BN381_80132	2.362e-81	275.0	COG0066@1|root,COG0066@2|Bacteria,2GJ8Z@201174|Actinobacteria,3UWGQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35	ko:K01704	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R03896,R03898,R03968,R04001,R10170	RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
BYD2_k127_6851686_2	1229780.BN381_80402	5.477e-149	479.0	COG0126@1|root,COG0126@2|Bacteria,2GJC6@201174|Actinobacteria,3UWA2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Phosphoglycerate kinase	pgk	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044464,GO:0071944	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
BYD2_k127_6851686_1	1229780.BN381_80401	4.752e-154	496.0	COG0057@1|root,COG0057@2|Bacteria,2GJK4@201174|Actinobacteria,3UW79@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the glyceraldehyde-3-phosphate dehydrogenase family	gapA	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
BYD2_k127_6851686_5	1229780.BN381_80400	8.451e-58	222.0	COG0391@1|root,COG0391@2|Bacteria,2GJBW@201174|Actinobacteria,3UXFA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Uncharacterised protein family UPF0052	-	-	-	-	-	-	-	-	-	-	-	-	UPF0052
BYD2_k127_6851686_3	1313172.YM304_21660	3.968e-93	314.0	COG1660@1|root,COG1660@2|Bacteria,2GMWB@201174|Actinobacteria,4CMXB@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Displays ATPase and GTPase activities	-	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
BYD2_k127_6851686_4	1313172.YM304_21650	1.118e-79	292.0	COG0500@1|root,COG2226@2|Bacteria,2HG5Z@201174|Actinobacteria,4CN2W@84992|Acidimicrobiia	84992|Acidimicrobiia	H	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_6851686_0	1313172.YM304_21620	2.208e-210	662.0	COG0322@1|root,COG0322@2|Bacteria,2GIS4@201174|Actinobacteria,4CMVA@84992|Acidimicrobiia	84992|Acidimicrobiia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,UVR,UvrC_HhH_N
BYD2_k127_6863987_3	1203605.HMPREF1531_01984	8.731e-146	477.0	COG1158@1|root,COG1158@2|Bacteria,2GIWY@201174|Actinobacteria,4DN0N@85009|Propionibacteriales	201174|Actinobacteria	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
BYD2_k127_6863987_21	330084.JNYZ01000004_gene518	8.577e-32	125.0	COG0254@1|root,COG0254@2|Bacteria,2IQ4I@201174|Actinobacteria,4E5FG@85010|Pseudonocardiales	201174|Actinobacteria	J	Binds the 23S rRNA	rpmE	GO:0008150,GO:0040007	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
BYD2_k127_6863987_18	1313172.YM304_10460	3.025e-42	171.0	28TNP@1|root,2ZFW6@2|Bacteria,2HAX0@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_6863987_1	1089544.KB912942_gene1878	7.917e-219	720.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4DXAD@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
BYD2_k127_6863987_9	1463825.JNXC01000017_gene6951	3.732e-100	344.0	COG0438@1|root,COG0438@2|Bacteria,2I005@201174|Actinobacteria,4DXXN@85010|Pseudonocardiales	201174|Actinobacteria	M	PFAM Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_6863987_7	1121877.JQKF01000003_gene1533	3.775e-128	420.0	COG0216@1|root,COG0216@2|Bacteria,2GJWG@201174|Actinobacteria,4CMPQ@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
BYD2_k127_6863987_13	1229780.BN381_10021	7.601e-70	261.0	COG2890@1|root,COG2890@2|Bacteria,2GMH1@201174|Actinobacteria,3UWRW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
BYD2_k127_6863987_22	1100721.ALKO01000017_gene1656	4.752e-29	131.0	COG0009@1|root,COG0009@2|Bacteria,1MVPM@1224|Proteobacteria,2VIFT@28216|Betaproteobacteria,4A9TY@80864|Comamonadaceae	28216|Betaproteobacteria	J	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	rimN	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
BYD2_k127_6863987_4	134676.ACPL_1995	2.104e-144	470.0	COG1253@1|root,COG1253@2|Bacteria,2GKN5@201174|Actinobacteria,4D92Y@85008|Micromonosporales	201174|Actinobacteria	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
BYD2_k127_6863987_16	452652.KSE_31020	1.557e-54	212.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,2M24B@2063|Kitasatospora	201174|Actinobacteria	KLT	Protein tyrosine kinase	pkaH	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
BYD2_k127_6863987_27	1229780.BN381_140034	3.421e-14	83.0	COG1309@1|root,COG1309@2|Bacteria,2GXGA@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_6863987_10	479432.Sros_4227	2.357e-92	312.0	COG3173@1|root,COG3173@2|Bacteria,2GKUU@201174|Actinobacteria,4EJ92@85012|Streptosporangiales	201174|Actinobacteria	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,Acetyltransf_3
BYD2_k127_6863987_20	590998.Celf_0512	2.438e-35	141.0	COG0346@1|root,COG0346@2|Bacteria,2IPGW@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase
BYD2_k127_6863987_28	1449346.JQMO01000003_gene6781	3.744e-05	48.0	COG1028@1|root,COG1028@2|Bacteria,2GW8A@201174|Actinobacteria,2M65G@2063|Kitasatospora	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_6863987_6	1283287.KB822580_gene1597	3.408e-142	465.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4DN00@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_6863987_23	1397527.Q670_09440	5.708e-26	115.0	COG3255@1|root,COG3255@2|Bacteria,1N01E@1224|Proteobacteria,1SBCB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	I	sterol carrier protein	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
BYD2_k127_6863987_5	1440774.Y900_025310	6.228e-144	471.0	COG0183@1|root,COG0183@2|Bacteria,2I3PP@201174|Actinobacteria,232HJ@1762|Mycobacteriaceae	201174|Actinobacteria	I	Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	-
BYD2_k127_6863987_25	1121372.AULK01000003_gene310	7.907e-23	109.0	COG0394@1|root,COG0394@2|Bacteria,2ISIM@201174|Actinobacteria,4FPY8@85023|Microbacteriaceae	201174|Actinobacteria	T	Low molecular weight phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	LMWPc
BYD2_k127_6863987_15	1229780.BN381_80386	5.684e-57	204.0	COG0698@1|root,COG0698@2|Bacteria,2GKJG@201174|Actinobacteria,3UWPM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
BYD2_k127_6863987_2	1229780.BN381_10027	2.312e-181	578.0	COG0112@1|root,COG0112@2|Bacteria,2GK7U@201174|Actinobacteria,3UWBD@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
BYD2_k127_6863987_8	1229780.BN381_10028	5.499e-114	383.0	COG0472@1|root,COG0472@2|Bacteria,2GIT7@201174|Actinobacteria,3UWGE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyl transferase family 4	rfe	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576	2.7.8.33,2.7.8.35	ko:K02851	-	-	R08856	RC00002	ko00000,ko01000,ko01003,ko01005	-	-	-	Glycos_transf_4
BYD2_k127_6863987_14	1121877.JQKF01000003_gene1526	3.864e-62	229.0	COG0356@1|root,COG0356@2|Bacteria,2H3PR@201174|Actinobacteria,4CN12@84992|Acidimicrobiia	84992|Acidimicrobiia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
BYD2_k127_6863987_24	1313172.YM304_10600	2.27e-24	104.0	COG0636@1|root,COG0636@2|Bacteria,2GQI6@201174|Actinobacteria,4CNBJ@84992|Acidimicrobiia	84992|Acidimicrobiia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_C
BYD2_k127_6863987_26	1454010.JEOE01000019_gene2347	1.054e-18	95.0	COG0711@1|root,COG0711@2|Bacteria,2GJS4@201174|Actinobacteria,4F167@85016|Cellulomonadaceae	201174|Actinobacteria	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
BYD2_k127_6863987_17	1313172.YM304_10630	3.944e-54	195.0	COG0712@1|root,COG0712@2|Bacteria,2HGFG@201174|Actinobacteria,4CND3@84992|Acidimicrobiia	84992|Acidimicrobiia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
BYD2_k127_6863987_0	1313172.YM304_10640	4.472e-235	764.0	COG0056@1|root,COG0056@2|Bacteria,2GJRJ@201174|Actinobacteria,4CMTI@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N
BYD2_k127_6863987_11	1313172.YM304_10650	2.142e-88	301.0	COG0224@1|root,COG3743@1|root,COG0224@2|Bacteria,COG3743@2|Bacteria,2GJ7Q@201174|Actinobacteria,4CN1H@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	-	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
BYD2_k127_6863987_12	1229780.BN381_10049	1.666e-70	244.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,3UW86@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
BYD2_k127_6865481_0	1463881.KL591018_gene271	2.528e-93	331.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,2ICGU@201174|Actinobacteria	201174|Actinobacteria	MV	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
BYD2_k127_69163_14	1313172.YM304_00110	4.706e-47	183.0	COG1748@1|root,COG1748@2|Bacteria,2H8X8@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_69163_17	266117.Rxyl_0591	3.771e-37	147.0	COG3415@1|root,COG3415@2|Bacteria,2I3JK@201174|Actinobacteria	201174|Actinobacteria	L	Protein of unknown function (DUF3105)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3105
BYD2_k127_69163_8	1429046.RR21198_5711	1.057e-81	282.0	COG3550@1|root,COG3550@2|Bacteria,2I2QD@201174|Actinobacteria,4G199@85025|Nocardiaceae	201174|Actinobacteria	S	MDMPI C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
BYD2_k127_69163_6	1123320.KB889662_gene1593	3.74e-95	340.0	COG0598@1|root,COG0598@2|Bacteria,2GKNZ@201174|Actinobacteria	201174|Actinobacteria	P	Magnesium transport protein CorA	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
BYD2_k127_69163_7	1229780.BN381_100201	1.627e-89	303.0	COG0483@1|root,COG0483@2|Bacteria,2GKZZ@201174|Actinobacteria,3UWIT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Inositol monophosphatase family	-	-	3.1.3.25	ko:K01092	ko00521,ko00562,ko01100,ko04070,map00521,map00562,map01100,map04070	M00131	R01185,R01186,R01187	RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
BYD2_k127_69163_15	285535.JOEY01000086_gene7198	9.121e-44	185.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_69163_16	525909.Afer_1728	8.244e-43	161.0	COG0764@1|root,COG0764@2|Bacteria,2GQWT@201174|Actinobacteria,4CN5K@84992|Acidimicrobiia	84992|Acidimicrobiia	I	FabA-like domain	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
BYD2_k127_69163_5	35754.JNYJ01000035_gene3877	1.068e-100	336.0	COG0623@1|root,COG0623@2|Bacteria,2GJ65@201174|Actinobacteria,4D93E@85008|Micromonosporales	201174|Actinobacteria	I	Enoyl- acyl-carrier-protein reductase NADH	inhA	GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0005504,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030312,GO:0030497,GO:0031406,GO:0032787,GO:0033293,GO:0034645,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.10,1.3.1.9	ko:K00208,ko:K11611	ko00061,ko00333,ko00780,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01100,map01130,map01212	M00083,M00572	R01404,R04429,R04430,R04724,R04725,R04955,R04956,R04958,R04959,R04961,R04962,R04966,R04967,R04969,R04970,R07765,R10118,R10122,R11671	RC00052,RC00076,RC00120	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
BYD2_k127_69163_3	1313172.YM304_21250	8.299e-111	391.0	COG4799@1|root,COG4799@2|Bacteria,2GIRU@201174|Actinobacteria,4CMQK@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Carboxyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
BYD2_k127_69163_2	457429.ABJI02000833_gene2518	9.441e-113	382.0	COG0304@1|root,COG0304@2|Bacteria,2GIY4@201174|Actinobacteria	201174|Actinobacteria	IQ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
BYD2_k127_69163_19	1121877.JQKF01000021_gene2200	5.204e-12	77.0	COG0236@1|root,COG0236@2|Bacteria,2HGA0@201174|Actinobacteria,4CN8U@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
BYD2_k127_69163_11	1120960.ATXG01000002_gene3106	6.509e-58	221.0	COG1028@1|root,COG1028@2|Bacteria,2GK6C@201174|Actinobacteria,4FKJF@85023|Microbacteriaceae	201174|Actinobacteria	IQ	KR domain	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
BYD2_k127_69163_9	1128421.JAGA01000002_gene1728	8.76e-81	287.0	COG0332@1|root,COG0332@2|Bacteria,2NNX5@2323|unclassified Bacteria	2|Bacteria	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
BYD2_k127_69163_20	1121877.JQKF01000021_gene2197	1.309e-08	63.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
BYD2_k127_69163_10	1313172.YM304_21340	2.999e-67	241.0	COG0331@1|root,COG0331@2|Bacteria,2GME0@201174|Actinobacteria,4CMPZ@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl transferase domain	-	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
BYD2_k127_69163_18	1449353.JQMQ01000005_gene3881	8.243e-15	85.0	COG0789@1|root,COG0789@2|Bacteria,2GKSZ@201174|Actinobacteria,2NF3J@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
BYD2_k127_69163_1	1206744.BAGL01000126_gene6146	2.579e-115	387.0	COG1680@1|root,COG1680@2|Bacteria,2GJJB@201174|Actinobacteria,4FXBC@85025|Nocardiaceae	201174|Actinobacteria	V	COG1680 Beta-lactamase class C and other penicillin binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_69163_0	1229780.BN381_70063	1.711e-229	721.0	COG4108@1|root,COG4108@2|Bacteria,2GKQA@201174|Actinobacteria,3UX1H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Class II release factor RF3, C-terminal domain	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,RF3_C
BYD2_k127_69163_4	479432.Sros_9211	4.326e-106	363.0	COG2021@1|root,COG2021@2|Bacteria,2I3HF@201174|Actinobacteria,4ER1D@85012|Streptosporangiales	201174|Actinobacteria	E	TAP-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_69163_13	649638.Trad_0869	5.958e-52	195.0	COG1876@1|root,COG1876@2|Bacteria	2|Bacteria	M	D-alanyl-D-alanine carboxypeptidase	vanY	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
BYD2_k127_69163_22	1229780.BN381_70060	0.0004185	47.0	COG1961@1|root,COG1961@2|Bacteria,2I8HV@201174|Actinobacteria	201174|Actinobacteria	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
BYD2_k127_69163_12	1048339.KB913029_gene1684	3.357e-53	201.0	COG0582@1|root,COG0582@2|Bacteria,2GMMI@201174|Actinobacteria,4ESP4@85013|Frankiales	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
BYD2_k127_700717_7	1313172.YM304_41680	3.175e-07	63.0	COG2175@1|root,COG2175@2|Bacteria,2I9TE@201174|Actinobacteria	201174|Actinobacteria	Q	Taurine catabolism dioxygenase TauD, TfdA family	-	-	-	-	-	-	-	-	-	-	-	-	TauD
BYD2_k127_700717_0	1313172.YM304_41670	8.937e-226	730.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
BYD2_k127_700717_1	1123023.JIAI01000002_gene4957	1.753e-91	313.0	COG2141@1|root,COG2141@2|Bacteria,2GJRF@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	1.5.98.2	ko:K00320	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R04464	RC01607	ko00000,ko00001,ko00002,ko01000	-	-	-	Bac_luciferase
BYD2_k127_700717_6	1206739.BAGJ01000273_gene4001	1.256e-23	109.0	2DK7W@1|root,308TR@2|Bacteria,2HJGY@201174|Actinobacteria,4G6RX@85025|Nocardiaceae	201174|Actinobacteria	S	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_700717_2	29581.BW37_04043	8.511e-70	268.0	COG3710@1|root,COG3903@1|root,COG3710@2|Bacteria,COG3903@2|Bacteria,1MWPD@1224|Proteobacteria,2WGNI@28216|Betaproteobacteria,47851@75682|Oxalobacteraceae	28216|Betaproteobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
BYD2_k127_700717_4	1449346.JQMO01000003_gene2801	4.217e-33	132.0	2AVP0@1|root,31MG1@2|Bacteria,2IN5B@201174|Actinobacteria	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_700717_3	479434.Sthe_1546	1.912e-53	195.0	COG1309@1|root,COG1309@2|Bacteria,2G9PQ@200795|Chloroflexi	200795|Chloroflexi	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
BYD2_k127_700717_5	436229.JOEH01000007_gene3944	4.49e-29	117.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,2NETG@228398|Streptacidiphilus	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7028639_9	1380356.JNIK01000004_gene91	1.84e-14	76.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
BYD2_k127_7028639_6	477641.MODMU_5094	2.767e-18	95.0	2EMIT@1|root,33F7D@2|Bacteria,2GRD4@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7028639_3	1133849.O3I_023575	4.62e-37	146.0	COG0346@1|root,COG0346@2|Bacteria,2IM1B@201174|Actinobacteria,4G29E@85025|Nocardiaceae	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_7028639_2	590998.Celf_0382	1.2e-53	198.0	COG1357@1|root,COG1357@2|Bacteria,2GN74@201174|Actinobacteria,4F2F0@85016|Cellulomonadaceae	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Pentapeptide
BYD2_k127_7028639_10	471853.Bcav_3732	5.141e-11	74.0	COG1357@1|root,COG1357@2|Bacteria,2GN74@201174|Actinobacteria	201174|Actinobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2,Pentapeptide
BYD2_k127_7028639_1	298653.Franean1_5551	2.384e-67	240.0	COG4762@1|root,COG4762@2|Bacteria,2INPU@201174|Actinobacteria,4EWSB@85013|Frankiales	201174|Actinobacteria	S	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7028639_7	1123320.KB889574_gene5580	1.481e-16	90.0	2EGCD@1|root,33A46@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF4190
BYD2_k127_7028639_8	1449355.JQNR01000005_gene4969	4.576e-16	87.0	COG3325@1|root,COG3325@2|Bacteria,2I852@201174|Actinobacteria	201174|Actinobacteria	G	Domain of unknown function (DUF3472)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3472,RicinB_lectin_2,Ricin_B_lectin
BYD2_k127_7028639_5	557599.MKAN_13960	1.303e-24	110.0	COG5485@1|root,COG5485@2|Bacteria,2INMM@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL,SnoaL_2
BYD2_k127_7028639_11	471852.Tcur_0039	1.053e-10	66.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria,4ENDN@85012|Streptosporangiales	201174|Actinobacteria	L	Phage integrase, N-terminal SAM-like domain	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_7028639_12	314278.NB231_12069	5.351e-09	64.0	291G3@1|root,33XP4@2|Bacteria,1NW6I@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7028639_4	479432.Sros_6088	3.363e-34	138.0	COG1695@1|root,COG1695@2|Bacteria,2IQ70@201174|Actinobacteria,4EKK9@85012|Streptosporangiales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
BYD2_k127_7028639_14	1464048.JNZS01000007_gene4320	1.13e-06	61.0	2EKBX@1|root,31ZVQ@2|Bacteria,2GY07@201174|Actinobacteria,4DGG3@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7028639_0	1038859.AXAU01000020_gene5488	8.278e-159	507.0	COG1028@1|root,COG1028@2|Bacteria,1MXNQ@1224|Proteobacteria,2TS6G@28211|Alphaproteobacteria,3JR9M@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_7028639_13	526225.Gobs_2978	4.548e-07	59.0	COG4974@1|root,COG4974@2|Bacteria,2I6VQ@201174|Actinobacteria,4EXH7@85013|Frankiales	201174|Actinobacteria	L	Phage integrase family	-	-	-	ko:K14059	-	-	-	-	ko00000	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_7045289_2	1229780.BN381_130089	1.914e-215	691.0	COG0855@1|root,COG0855@2|Bacteria,2GJ0B@201174|Actinobacteria,3UWBN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	P	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	GO:0000287,GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0008976,GO:0009267,GO:0009405,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0015968,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019538,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0040007,GO:0042594,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0046872,GO:0050896,GO:0051704,GO:0051716,GO:0070482,GO:0071496,GO:0071704,GO:0071944,GO:1901564	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
BYD2_k127_7045289_11	1313172.YM304_07670	3.343e-34	135.0	2FBA6@1|root,343GA@2|Bacteria,2H78Y@201174|Actinobacteria,4CN8Z@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7045289_4	1229780.BN381_130087	3.233e-90	316.0	COG0265@1|root,COG0265@2|Bacteria,2GJ96@201174|Actinobacteria,3UWP8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Trypsin	-	-	3.4.21.107	ko:K04771,ko:K08372	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
BYD2_k127_7045289_14	1313172.YM304_07660	6.505e-23	115.0	2CC1Y@1|root,32TCV@2|Bacteria,2HGD4@201174|Actinobacteria,4CNAQ@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
BYD2_k127_7045289_15	278957.ABEA03000195_gene543	5.364e-08	63.0	COG1826@1|root,COG1826@2|Bacteria,46WPX@74201|Verrucomicrobia,3K8HZ@414999|Opitutae	414999|Opitutae	U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system	-	-	-	ko:K03116	ko03060,ko03070,map03060,map03070	M00336	-	-	ko00000,ko00001,ko00002,ko02044	2.A.64	-	-	MttA_Hcf106
BYD2_k127_7045289_5	525909.Afer_0329	4.194e-75	267.0	COG3643@1|root,COG3643@2|Bacteria,2H8ZI@201174|Actinobacteria,4CNR1@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Formiminotransferase domain, N-terminal subdomain	-	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD_N
BYD2_k127_7045289_12	1313172.YM304_07630	4.051e-33	138.0	2CC1Y@1|root,32RUK@2|Bacteria,2IQ4Q@201174|Actinobacteria,4CP4B@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA	-	-	-	ko:K18955	-	-	-	-	ko00000,ko03000	-	-	-	Whib
BYD2_k127_7045289_7	1313172.YM304_05900	1.122e-61	217.0	COG2110@1|root,COG2110@2|Bacteria,2IFEC@201174|Actinobacteria	201174|Actinobacteria	S	domain protein	lppD	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Macro
BYD2_k127_7045289_0	1313172.YM304_07620	7.095e-275	868.0	COG4867@1|root,COG4867@2|Bacteria,2H14W@201174|Actinobacteria,4CMU5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7045289_13	2074.JNYD01000001_gene6207	3.576e-24	106.0	COG4298@1|root,COG4298@2|Bacteria,2IQ7S@201174|Actinobacteria,4E5WN@85010|Pseudonocardiales	201174|Actinobacteria	S	yiaA/B two helix domain	-	-	-	-	-	-	-	-	-	-	-	-	YiaAB
BYD2_k127_7045289_8	1120936.KB907223_gene2433	2.359e-60	221.0	COG2723@1|root,COG2723@2|Bacteria	2|Bacteria	G	beta-glucosidase activity	bglB	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1
BYD2_k127_7045289_9	1380356.JNIK01000011_gene1782	1.701e-46	178.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_7045289_3	1449353.JQMQ01000005_gene2038	9.961e-159	526.0	COG0726@1|root,COG1215@1|root,COG0726@2|Bacteria,COG1215@2|Bacteria,2GJCE@201174|Actinobacteria,2NF3C@228398|Streptacidiphilus	201174|Actinobacteria	GM	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Polysacc_deac_1
BYD2_k127_7045289_1	1313172.YM304_07520	5.895e-226	707.0	COG1239@1|root,COG1239@2|Bacteria,2GMRS@201174|Actinobacteria,4CMSG@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Mg-chelatase subunit ChlI	-	-	6.6.1.1	ko:K03405	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R03877	RC01012	ko00000,ko00001,ko01000	-	-	-	-
BYD2_k127_7045289_6	103733.JNYO01000001_gene37	2.049e-62	225.0	COG1075@1|root,COG1075@2|Bacteria,2GJGC@201174|Actinobacteria,4E1WR@85010|Pseudonocardiales	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_7045289_10	2002.JOEQ01000041_gene6030	2.034e-37	147.0	COG1595@1|root,COG1595@2|Bacteria,2HGII@201174|Actinobacteria,4EIX7@85012|Streptosporangiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7080480_2	1157637.KB892095_gene2779	1.763e-34	133.0	COG2243@1|root,COG2243@2|Bacteria,2GJFA@201174|Actinobacteria	201174|Actinobacteria	H	synthase	cobF	-	2.1.1.152	ko:K02228	ko00860,ko01100,map00860,map01100	-	R05219	RC00003,RC00923,RC02890	ko00000,ko00001,ko01000	-	-	-	TP_methylase
BYD2_k127_7080480_1	68219.JNXI01000004_gene2788	1.055e-71	250.0	COG2099@1|root,COG2099@2|Bacteria,2GMYZ@201174|Actinobacteria	201174|Actinobacteria	H	reductase	cobK	-	1.3.1.106,1.3.1.54	ko:K05895	ko00860,ko01100,map00860,map01100	-	R05150,R05812	RC01280	ko00000,ko00001,ko01000	-	-	-	CbiJ
BYD2_k127_7080480_0	1313172.YM304_20410	2.087e-263	822.0	COG3653@1|root,COG3653@2|Bacteria,2GKMK@201174|Actinobacteria	201174|Actinobacteria	Q	N-acyl-D-aspartate D-glutamate deacylase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
BYD2_k127_7102126_15	33898.JRHJ01000069_gene7008	7.798e-68	245.0	COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria	201174|Actinobacteria	S	metallophosphoesterase	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos
BYD2_k127_7102126_28	1160137.KB907307_gene102	0.0001	52.0	2DM23@1|root,31DUR@2|Bacteria,2GIYZ@201174|Actinobacteria,4G0NI@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF2204,NTP_transf_5
BYD2_k127_7102126_8	1122611.KB904029_gene5400	1.475e-107	357.0	COG1216@1|root,COG1216@2|Bacteria,2GKS6@201174|Actinobacteria,4EIPY@85012|Streptosporangiales	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_2
BYD2_k127_7102126_24	35754.JNYJ01000022_gene8077	1.729e-29	123.0	COG1595@1|root,COG1595@2|Bacteria,2GWFT@201174|Actinobacteria,4DJEK@85008|Micromonosporales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7102126_20	66373.JOFQ01000008_gene103	1.28e-46	171.0	2DM0Y@1|root,318KY@2|Bacteria,2IMIX@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1992
BYD2_k127_7102126_9	326424.FRAAL4766	3.442e-106	350.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_7102126_26	66875.JODY01000032_gene4265	2.532e-23	103.0	COG1917@1|root,COG1917@2|Bacteria,2IKKG@201174|Actinobacteria	201174|Actinobacteria	S	ChrR Cupin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_7
BYD2_k127_7102126_1	1150599.MPHLEI_03738	2.722e-225	703.0	COG0183@1|root,COG0183@2|Bacteria,2GIY0@201174|Actinobacteria,234II@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the thiolase family	ltp1_1	-	-	-	-	-	-	-	-	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_7102126_19	1440774.Y900_026270	1.633e-54	196.0	COG1545@1|root,COG1545@2|Bacteria,2IH6P@201174|Actinobacteria,23998@1762|Mycobacteriaceae	201174|Actinobacteria	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	DUF35_N,OB_aCoA_assoc
BYD2_k127_7102126_10	414684.RC1_3591	2.939e-100	347.0	COG3386@1|root,COG3386@2|Bacteria,1MXVD@1224|Proteobacteria,2TVCW@28211|Alphaproteobacteria,2JQUA@204441|Rhodospirillales	204441|Rhodospirillales	G	SMP-30/Gluconolaconase/LRE-like region	-	-	3.1.1.17	ko:K01053	ko00030,ko00053,ko00930,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,map00030,map00053,map00930,map01100,map01110,map01120,map01130,map01200,map01220	M00129	R01519,R02933,R03751	RC00537,RC00983	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	SGL
BYD2_k127_7102126_13	644283.Micau_2889	2.612e-82	301.0	COG1801@1|root,COG1801@2|Bacteria,2HU1R@201174|Actinobacteria,4DADR@85008|Micromonosporales	201174|Actinobacteria	S	Protein of unknown function DUF72	-	-	-	-	-	-	-	-	-	-	-	-	DUF72
BYD2_k127_7102126_7	1380390.JIAT01000010_gene4057	1.715e-110	375.0	COG0615@1|root,COG2870@1|root,COG0615@2|Bacteria,COG2870@2|Bacteria,2GKU1@201174|Actinobacteria,4CRDH@84995|Rubrobacteria	84995|Rubrobacteria	H	Cytidylyltransferase-like	-	-	2.7.1.167,2.7.7.70	ko:K03272	ko00540,ko01100,map00540,map01100	M00064	R05644,R05646	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_like,PfkB
BYD2_k127_7102126_21	110319.CF8_0780	1.704e-38	151.0	COG2323@1|root,COG2323@2|Bacteria,2IIPT@201174|Actinobacteria,4DVWR@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF421)	-	-	-	-	-	-	-	-	-	-	-	-	DUF421
BYD2_k127_7102126_23	1463909.KL585970_gene1172	2.225e-35	139.0	COG0517@1|root,COG0517@2|Bacteria,2IHPB@201174|Actinobacteria	201174|Actinobacteria	S	Cbs domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
BYD2_k127_7102126_2	43354.JOIJ01000008_gene3082	1.177e-166	560.0	COG1063@1|root,COG1063@2|Bacteria,2GISW@201174|Actinobacteria,4DXR5@85010|Pseudonocardiales	201174|Actinobacteria	E	PFAM Alcohol dehydrogenase GroES-like	fdh	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N
BYD2_k127_7102126_5	326424.FRAAL1797	7.924e-120	394.0	COG2141@1|root,COG2141@2|Bacteria,2GM94@201174|Actinobacteria,4EU4E@85013|Frankiales	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_7102126_17	590998.Celf_2592	1.693e-62	219.0	COG0241@1|root,COG1216@1|root,COG0241@2|Bacteria,COG1216@2|Bacteria,2GK77@201174|Actinobacteria	201174|Actinobacteria	E	D,D-heptose 1,7-bisphosphate phosphatase	gmhB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Hydrolase_like
BYD2_k127_7102126_11	1134445.AJJM01000062_gene1648	1.472e-90	312.0	COG0859@1|root,COG0859@2|Bacteria,2GSTW@201174|Actinobacteria	201174|Actinobacteria	M	PFAM glycosyl transferase family 9	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_9,Hydrolase_like
BYD2_k127_7102126_4	1380347.JNII01000006_gene1120	4.119e-128	437.0	COG0297@1|root,COG0297@2|Bacteria,2I2EE@201174|Actinobacteria,4EUJN@85013|Frankiales	201174|Actinobacteria	G	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_7102126_18	266117.Rxyl_0712	7.576e-60	222.0	COG0279@1|root,COG0279@2|Bacteria,2HPYA@201174|Actinobacteria,4CTV4@84995|Rubrobacteria	84995|Rubrobacteria	G	SIS domain	-	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	SIS_2
BYD2_k127_7102126_0	909613.UO65_1465	4.235e-228	718.0	COG2192@1|root,COG2192@2|Bacteria,2GJHV@201174|Actinobacteria,4E0TN@85010|Pseudonocardiales	201174|Actinobacteria	O	carbamoyl transferase, NodU family	-	-	-	ko:K00612	-	-	-	-	ko00000,ko01000	-	-	-	Carbam_trans_C,Carbam_trans_N
BYD2_k127_7102126_12	1120936.KB907210_gene5548	9.98e-90	317.0	COG0241@1|root,COG1216@1|root,COG0241@2|Bacteria,COG1216@2|Bacteria,2GK77@201174|Actinobacteria,4EI4M@85012|Streptosporangiales	201174|Actinobacteria	E	HAD-hyrolase-like	gmhB	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Hydrolase_like
BYD2_k127_7102126_16	1540221.JQNI01000004_gene331	2.437e-65	251.0	COG0859@1|root,COG0859@2|Bacteria	2|Bacteria	M	ADP-heptose-lipopolysaccharide heptosyltransferase activity	rfaF	-	-	ko:K02843	ko00540,ko01100,map00540,map01100	M00080	-	-	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT9	-	Glyco_transf_9
BYD2_k127_7102126_6	1476583.DEIPH_ctg011orf0137	3.305e-118	413.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	rfaG	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glycos_transf_1
BYD2_k127_7102126_14	263358.VAB18032_14355	9.681e-78	267.0	COG0300@1|root,COG0300@2|Bacteria,2I5HR@201174|Actinobacteria,4DMNM@85008|Micromonosporales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_7102126_3	222534.KB893730_gene5755	2.253e-160	514.0	COG1633@1|root,COG1633@2|Bacteria,2H9MT@201174|Actinobacteria,4EUIY@85013|Frankiales	201174|Actinobacteria	S	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7102126_22	1380386.JIAW01000017_gene3026	8.725e-38	151.0	2ADQJ@1|root,313FX@2|Bacteria,2H0DG@201174|Actinobacteria,23549@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7108568_3	1313172.YM304_24920	9.632e-12	78.0	COG4974@1|root,COG4974@2|Bacteria,2GNDP@201174|Actinobacteria,4CMZU@84992|Acidimicrobiia	84992|Acidimicrobiia	D	Phage integrase, N-terminal SAM-like domain	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
BYD2_k127_7108568_2	47716.JOFH01000049_gene3280	1.182e-19	91.0	COG2331@1|root,COG2331@2|Bacteria,2GR6C@201174|Actinobacteria	201174|Actinobacteria	S	Regulatory protein, FmdB family	-	-	-	-	-	-	-	-	-	-	-	-	Zn-ribbon_8
BYD2_k127_7108568_1	1229780.BN381_290082	2.596e-39	166.0	COG0494@1|root,COG0494@2|Bacteria,2GNW6@201174|Actinobacteria,3UWWT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	NTP pyrophosphohydrolases including oxidative damage repair enzymes	nudF	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
BYD2_k127_7108568_0	1313172.YM304_24900	1.558e-252	787.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CMQD@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
BYD2_k127_7123836_0	1122609.AUGT01000002_gene3817	2.505e-99	340.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4DNDC@85009|Propionibacteriales	201174|Actinobacteria	P	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_7123836_1	1120950.KB892776_gene799	6.737e-54	199.0	COG4585@1|root,COG4585@2|Bacteria,2GKV2@201174|Actinobacteria,4DTME@85009|Propionibacteriales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
BYD2_k127_7129519_4	1463861.JNXE01000003_gene3938	2.977e-27	112.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_7129519_0	298655.KI912266_gene5843	1.34e-237	743.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_7129519_1	298654.FraEuI1c_3325	7.638e-152	499.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ES6E@85013|Frankiales	2|Bacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K18661	ko00280,map00280	-	R03383	RC00004,RC00137	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_7129519_3	931627.MycrhDRAFT_6484	9.735e-64	244.0	COG4221@1|root,COG4221@2|Bacteria,2I5VE@201174|Actinobacteria,23FGZ@1762|Mycobacteriaceae	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_7129519_2	1122247.C731_4817	1.635e-114	385.0	COG0318@1|root,COG0318@2|Bacteria,2GK1Y@201174|Actinobacteria,236Q2@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_713614_2	1229780.BN381_430009	4.128e-209	682.0	COG1012@1|root,COG1012@2|Bacteria,2HEX0@201174|Actinobacteria,3UWBJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
BYD2_k127_713614_3	882083.SacmaDRAFT_1824	1.386e-176	564.0	COG0160@1|root,COG0160@2|Bacteria,2GKVH@201174|Actinobacteria,4DZMQ@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family	-	-	1.2.1.18,1.2.1.27,2.6.1.19	ko:K00140,ko:K00823	ko00250,ko00280,ko00410,ko00562,ko00640,ko00650,ko01100,ko01120,ko01200,map00250,map00280,map00410,map00562,map00640,map00650,map01100,map01120,map01200	M00013,M00027	R00705,R00706,R00908,R00922,R00935,R01648	RC00004,RC00006,RC00062,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
BYD2_k127_713614_9	1229780.BN381_430010	8.244e-153	494.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
BYD2_k127_713614_8	1048339.KB913029_gene1694	4.725e-154	506.0	COG0467@1|root,COG0467@2|Bacteria,2I58C@201174|Actinobacteria	201174|Actinobacteria	T	KaiC	-	-	-	ko:K08482	-	-	-	-	ko00000	-	-	-	ATPase
BYD2_k127_713614_15	1089546.AQUI01000002_gene894	6.877e-20	100.0	COG0745@1|root,COG0745@2|Bacteria	1089546.AQUI01000002_gene894|-	T	phosphorelay signal transduction system	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_713614_17	665959.HMPREF1013_02117	1.954e-10	71.0	COG0789@1|root,COG5012@1|root,COG0789@2|Bacteria,COG5012@2|Bacteria,1TQ3N@1239|Firmicutes,4HC1T@91061|Bacilli,1ZR6Y@1386|Bacillus	91061|Bacilli	K	B12 binding domain	-	-	-	ko:K22491	-	-	-	-	ko00000,ko03000	-	-	-	B12-binding,B12-binding_2,MerR_1
BYD2_k127_713614_18	2055.JNXA01000001_gene2117	5.864e-09	62.0	COG1366@1|root,COG1366@2|Bacteria,2HX78@201174|Actinobacteria,4GEJS@85026|Gordoniaceae	201174|Actinobacteria	T	STAS domain	-	-	-	-	-	-	-	-	-	-	-	-	STAS_2
BYD2_k127_713614_16	1229203.KI301992_gene583	8.313e-16	82.0	COG2172@1|root,COG2172@2|Bacteria,2IBHV@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,PAS
BYD2_k127_713614_0	1229780.BN381_430022	4.074e-242	779.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,3UWEA@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	1.2.1.19	ko:K00137	ko00330,ko00410,ko01100,map00330,map00410,map01100	-	R02549	RC00080	ko00000,ko00001,ko01000	-	-	-	Aldedh
BYD2_k127_713614_4	350054.Mflv_3138	2.401e-171	546.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,2329P@1762|Mycobacteriaceae	201174|Actinobacteria	E	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K02052,ko:K11072	ko02010,ko02024,map02010,map02024	M00193,M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11,3.A.1.11.1	-	-	ABC_tran,TOBE_2
BYD2_k127_713614_7	350054.Mflv_3137	2.066e-157	508.0	COG0687@1|root,COG0687@2|Bacteria,2GKVG@201174|Actinobacteria,232YQ@1762|Mycobacteriaceae	201174|Actinobacteria	E	Extracellular solute-binding protein	-	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	SBP_bac_6,SBP_bac_8
BYD2_k127_713614_11	710686.Mycsm_03531	1.653e-136	456.0	COG1176@1|root,COG1176@2|Bacteria,2GJ5G@201174|Actinobacteria,233PW@1762|Mycobacteriaceae	201174|Actinobacteria	P	ABC-type spermidine putrescine transport system, permease component I	potH	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
BYD2_k127_713614_12	1298864.AUEQ01000007_gene2139	1.147e-120	395.0	COG1177@1|root,COG1177@2|Bacteria,2GJ6Q@201174|Actinobacteria,232G4@1762|Mycobacteriaceae	201174|Actinobacteria	E	inner membrane component	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
BYD2_k127_713614_1	1229780.BN381_430027	1.755e-217	682.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,3UWEC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class-III	tpa	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
BYD2_k127_713614_5	1229780.BN381_430028	1.293e-162	538.0	COG0686@1|root,COG0686@2|Bacteria,2GJ6G@201174|Actinobacteria,3UWER@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Belongs to the AlaDH PNT family	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
BYD2_k127_713614_14	1229780.BN381_430029	1.604e-51	202.0	COG1522@1|root,COG1522@2|Bacteria,2GP1P@201174|Actinobacteria,3UWRS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix ASNC type	-	-	-	ko:K03718	-	-	-	-	ko00000,ko03000	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
BYD2_k127_713614_6	1229780.BN381_430030	4.284e-160	546.0	COG0665@1|root,COG0665@2|Bacteria,2GJQ9@201174|Actinobacteria,3UX6S@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO
BYD2_k127_713614_10	1229780.BN381_430031	3.966e-147	477.0	COG0161@1|root,COG0161@2|Bacteria,2GKF6@201174|Actinobacteria,3UWEC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Aminotransferase class-III	bioA2	-	-	-	-	-	-	-	-	-	-	-	Aminotran_3
BYD2_k127_713614_13	700508.D174_15535	8.235e-61	218.0	28KNT@1|root,2ZA6Z@2|Bacteria,2GNXC@201174|Actinobacteria,233P9@1762|Mycobacteriaceae	201174|Actinobacteria	S	EthD domain	-	-	-	-	-	-	-	-	-	-	-	-	EthD
BYD2_k127_7141364_15	1048339.KB913029_gene3767	3.95e-30	133.0	COG2267@1|root,COG2267@2|Bacteria,2HM71@201174|Actinobacteria,4EWBI@85013|Frankiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_7141364_0	1283283.ATXA01000024_gene208	9.844e-146	486.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7141364_14	390989.JOEG01000005_gene2000	4.189e-46	193.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4D92W@85008|Micromonosporales	201174|Actinobacteria	KT	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
BYD2_k127_7141364_8	1313172.YM304_02490	4.19e-94	318.0	COG0077@1|root,COG0077@2|Bacteria,2GJQ5@201174|Actinobacteria,4CN0G@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Prephenate dehydratase	pheA	-	4.2.1.51	ko:K04518	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024	R00691,R01373	RC00360	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDT
BYD2_k127_7141364_16	222534.KB893746_gene2680	0.0001415	55.0	2ECHS@1|root,336G1@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7141364_9	1449346.JQMO01000003_gene2710	6.659e-94	317.0	COG0363@1|root,COG0363@2|Bacteria,2GK7F@201174|Actinobacteria,2M468@2063|Kitasatospora	201174|Actinobacteria	G	Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase	nagB	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
BYD2_k127_7141364_10	298654.FraEuI1c_3027	9.953e-86	307.0	COG1820@1|root,COG1820@2|Bacteria,2GK1E@201174|Actinobacteria,4ESGN@85013|Frankiales	201174|Actinobacteria	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
BYD2_k127_7141364_11	1306174.JODP01000009_gene6415	1.516e-67	247.0	COG1940@1|root,COG1940@2|Bacteria,2GZ27@201174|Actinobacteria	201174|Actinobacteria	GK	ROK family	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
BYD2_k127_7141364_1	1236902.ANAS01000037_gene5391	3.357e-126	427.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EMXE@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
BYD2_k127_7141364_4	543632.JOJL01000026_gene2566	4.584e-106	368.0	COG1472@1|root,COG1472@2|Bacteria,2GM43@201174|Actinobacteria,4DBH4@85008|Micromonosporales	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
BYD2_k127_7141364_7	2045.KR76_21065	2.227e-95	323.0	COG0395@1|root,COG0395@2|Bacteria,2GKEE@201174|Actinobacteria,4DQP3@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	dasC	-	-	ko:K02026,ko:K17331	ko02010,map02010	M00207,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.33	-	-	BPD_transp_1
BYD2_k127_7141364_6	1122609.AUGT01000009_gene2987	2.47e-98	336.0	COG1175@1|root,COG1175@2|Bacteria,2GX5P@201174|Actinobacteria,4DQP0@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17330	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	BPD_transp_1
BYD2_k127_7141364_2	1122609.AUGT01000009_gene2986	1.494e-108	371.0	COG1653@1|root,COG1653@2|Bacteria,2GKM8@201174|Actinobacteria,4DQWX@85009|Propionibacteriales	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K17329	ko02010,map02010	M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.33	-	-	SBP_bac_1,SBP_bac_8
BYD2_k127_7141364_3	590998.Celf_1346	5.642e-107	359.0	COG1940@1|root,COG1940@2|Bacteria,2GKMZ@201174|Actinobacteria,4F0SY@85016|Cellulomonadaceae	201174|Actinobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	Crp,ROK
BYD2_k127_7141364_12	1125863.JAFN01000001_gene1413	9.695e-56	207.0	COG1691@1|root,COG1691@2|Bacteria,1REQ7@1224|Proteobacteria,42MJG@68525|delta/epsilon subdivisions,2WN0G@28221|Deltaproteobacteria	28221|Deltaproteobacteria	S	PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
BYD2_k127_7141364_5	1463934.JOCF01000023_gene6232	9.59e-99	346.0	COG1641@1|root,COG1641@2|Bacteria,2I8J1@201174|Actinobacteria	201174|Actinobacteria	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
BYD2_k127_7141364_13	477641.MODMU_0214	2.151e-47	194.0	arCOG06227@1|root,2ZCRG@2|Bacteria,2I96P@201174|Actinobacteria,4ETHW@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF4397)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4397
BYD2_k127_7143900_1	446470.Snas_6221	7.367e-50	179.0	COG1017@1|root,COG1018@1|root,COG1017@2|Bacteria,COG1018@2|Bacteria,2GKXT@201174|Actinobacteria,4EZFF@85014|Glycomycetales	201174|Actinobacteria	C	Globin	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,Globin,NAD_binding_1
BYD2_k127_7143900_4	1463821.JOGR01000001_gene1439	1.606e-30	125.0	COG2346@1|root,COG2346@2|Bacteria,2GQFN@201174|Actinobacteria	201174|Actinobacteria	S	Group 1 truncated hemoglobin	glbN	GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057	-	ko:K06886	-	-	-	-	ko00000	-	-	-	Bac_globin
BYD2_k127_7143900_3	693746.OBV_19180	6.493e-39	151.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,2N776@216572|Oscillospiraceae	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
BYD2_k127_7143900_2	710111.FraQA3DRAFT_2939	8.141e-47	181.0	COG1985@1|root,COG1985@2|Bacteria,2GN2P@201174|Actinobacteria,4ET37@85013|Frankiales	201174|Actinobacteria	H	PFAM bifunctional deaminase-reductase domain protein	ribD	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_7143900_0	525909.Afer_1025	0.0	1173.0	COG0209@1|root,COG1372@1|root,COG0209@2|Bacteria,COG1372@2|Bacteria,2GKX9@201174|Actinobacteria,4CN7I@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_2_N,Ribonuc_red_lgC
BYD2_k127_7154196_4	1306406.ASHX01000002_gene4710	0.0007303	48.0	2E6NT@1|root,33198@2|Bacteria,2IFTP@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7154196_0	1283299.AUKG01000001_gene3104	2.738e-104	351.0	COG3569@1|root,COG3569@2|Bacteria,2GJTH@201174|Actinobacteria,4CR90@84995|Rubrobacteria	84995|Rubrobacteria	L	Eukaryotic DNA topoisomerase I, catalytic core	-	-	-	-	-	-	-	-	-	-	-	-	Topoisom_I
BYD2_k127_7154196_1	1386089.N865_00415	9.994e-37	144.0	2C72U@1|root,32W8F@2|Bacteria,2GTSA@201174|Actinobacteria,4FHME@85021|Intrasporangiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7154196_3	1192034.CAP_2968	1.629e-09	67.0	COG4914@1|root,COG4914@2|Bacteria,1QX3W@1224|Proteobacteria,42ZWQ@68525|delta/epsilon subdivisions,2WVG3@28221|Deltaproteobacteria,2Z3HN@29|Myxococcales	28221|Deltaproteobacteria	S	Nucleotidyl transferase of unknown function (DUF2204)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2204
BYD2_k127_7154196_2	1110697.NCAST_08_02660	1.395e-27	112.0	COG2129@1|root,COG2129@2|Bacteria,2GJ72@201174|Actinobacteria,4FVD2@85025|Nocardiaceae	201174|Actinobacteria	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	-	-	-	-	-	-	-	-	-	Metallophos,Metallophos_2
BYD2_k127_7175865_1	1313172.YM304_19420	1.881e-110	374.0	COG0769@1|root,COG0769@2|Bacteria,2GIS2@201174|Actinobacteria,4CNID@84992|Acidimicrobiia	84992|Acidimicrobiia	M	acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	-	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
BYD2_k127_7175865_0	1229780.BN381_140011	2.612e-134	437.0	COG0472@1|root,COG0472@2|Bacteria,2GNEH@201174|Actinobacteria,3UWA7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	GO:0008150,GO:0040007	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
BYD2_k127_7175865_4	370438.PTH_1862	2.318e-86	301.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,2619Y@186807|Peptococcaceae	186801|Clostridia	D	Belongs to the SEDS family	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
BYD2_k127_7175865_5	1229780.BN381_140009	7.378e-84	314.0	COG0707@1|root,COG0707@2|Bacteria,2GJEM@201174|Actinobacteria,3UWKB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
BYD2_k127_7175865_3	742818.HMPREF9451_01103	2.143e-89	317.0	COG0773@1|root,COG0773@2|Bacteria,2I2E7@201174|Actinobacteria,4CUCI@84998|Coriobacteriia	84998|Coriobacteriia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
BYD2_k127_7175865_2	1313172.YM304_19480	1.928e-89	306.0	COG0812@1|root,COG0812@2|Bacteria,2HG0Y@201174|Actinobacteria,4CMXR@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Cell wall formation	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
BYD2_k127_7175865_7	1445613.JALM01000061_gene3371	2.461e-15	86.0	COG1589@1|root,COG1589@2|Bacteria,2H4A4@201174|Actinobacteria,4E3DB@85010|Pseudonocardiales	201174|Actinobacteria	D	Cell division protein FtsQ	ftsQ	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0071944	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
BYD2_k127_7175865_6	326424.FRAAL2200	4.855e-67	231.0	COG0206@1|root,COG0206@2|Bacteria,2GJWC@201174|Actinobacteria,4ERQ5@85013|Frankiales	201174|Actinobacteria	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	GO:0000166,GO:0000287,GO:0000910,GO:0000921,GO:0000935,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032155,GO:0032185,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0045787,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051258,GO:0051301,GO:0051726,GO:0065003,GO:0065007,GO:0070925,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
BYD2_k127_7178121_16	1303692.SFUL_3342	3.374e-09	64.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
BYD2_k127_7178121_10	710696.Intca_0369	9.791e-34	136.0	COG0596@1|root,COG1506@1|root,COG3710@1|root,COG0596@2|Bacteria,COG1506@2|Bacteria,COG3710@2|Bacteria,2HASC@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
BYD2_k127_7178121_17	1121447.JONL01000001_gene735	8.033e-08	55.0	2EG8N@1|root,33A0G@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7178121_7	446470.Snas_1414	6.653e-50	194.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4EXY2@85014|Glycomycetales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_7178121_11	298655.KI912266_gene3160	7.29e-32	131.0	COG1695@1|root,COG1695@2|Bacteria,2IH28@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_7178121_5	1229780.BN381_190005	7.219e-59	209.0	COG1666@1|root,COG1666@2|Bacteria,2IFIU@201174|Actinobacteria,3UWND@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function (DUF520)	trpF	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	ko:K09767	-	-	-	-	ko00000	-	-	-	DUF520
BYD2_k127_7178121_3	246194.CHY_0108	5.112e-84	291.0	COG0501@1|root,COG0501@2|Bacteria,1TP23@1239|Firmicutes,24ACH@186801|Clostridia,42GEA@68295|Thermoanaerobacterales	186801|Clostridia	O	Belongs to the peptidase M48B family	htpX	-	-	ko:K03799	-	M00743	-	-	ko00000,ko00002,ko01000,ko01002	-	-	-	Peptidase_M48
BYD2_k127_7178121_15	1247963.JPHU01000001_gene1923	1.05e-17	89.0	COG0546@1|root,COG0546@2|Bacteria,1RED3@1224|Proteobacteria,2U7YV@28211|Alphaproteobacteria	28211|Alphaproteobacteria	S	phosphoglycolate phosphatase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acid_phosphat_B
BYD2_k127_7178121_14	1445613.JALM01000036_gene2694	9.938e-18	90.0	COG1247@1|root,COG1247@2|Bacteria,2GR9D@201174|Actinobacteria,4EF6Z@85010|Pseudonocardiales	201174|Actinobacteria	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_7178121_0	1313172.YM304_35460	2.083e-319	993.0	COG0365@1|root,COG0365@2|Bacteria,2GJCG@201174|Actinobacteria,4CMRX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	AMP-binding enzyme C-terminal domain	-	-	6.2.1.1	ko:K01895	ko00010,ko00620,ko00640,ko00680,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00620,map00640,map00680,map00720,map01100,map01110,map01120,map01130,map01200	M00357	R00235,R00236,R00316,R00926,R01354	RC00004,RC00012,RC00043,RC00070,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACAS_N,AMP-binding,AMP-binding_C
BYD2_k127_7178121_12	645465.ACUR01000602_gene808	6.287e-31	132.0	COG1309@1|root,COG1309@2|Bacteria,2GV75@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
BYD2_k127_7178121_9	1206725.BAFU01000052_gene1566	3.076e-34	146.0	2BVHN@1|root,32QW3@2|Bacteria,2IKWS@201174|Actinobacteria,4G0IU@85025|Nocardiaceae	201174|Actinobacteria	S	Pfam:DUF385	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
BYD2_k127_7178121_13	1333998.M2A_2779	3.843e-30	129.0	COG2050@1|root,COG2050@2|Bacteria,1REK6@1224|Proteobacteria,2U8H6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_7178121_6	1463879.JOHP01000038_gene6870	1.78e-53	203.0	COG0500@1|root,COG2226@2|Bacteria,2GP9N@201174|Actinobacteria	201174|Actinobacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_7178121_4	1313172.YM304_35500	2.284e-72	280.0	COG1565@1|root,COG1565@2|Bacteria	2|Bacteria	P	acr, cog1565	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_28
BYD2_k127_7178121_2	1229780.BN381_160034	3.133e-172	554.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,3UWFY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN2	-	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
BYD2_k127_7178121_1	1229780.BN381_160033	1.643e-220	694.0	COG1008@1|root,COG1008@2|Bacteria,2GKBN@201174|Actinobacteria,3UWBE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	nuoM2	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
BYD2_k127_7178121_8	1229780.BN381_160032	1.843e-39	152.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,3UWAP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	CP	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
BYD2_k127_7181113_5	1229780.BN381_130117	5.383e-180	589.0	COG2936@1|root,COG2936@2|Bacteria,2IAA6@201174|Actinobacteria,3UXM3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K06978	-	-	-	-	ko00000	-	-	-	PepX_C,Peptidase_S15
BYD2_k127_7181113_4	1229780.BN381_70026	2.457e-190	601.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWHR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.16,2.3.1.9	ko:K00626,ko:K00632	ko00071,ko00072,ko00280,ko00281,ko00310,ko00362,ko00380,ko00592,ko00620,ko00630,ko00640,ko00642,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00281,map00310,map00362,map00380,map00592,map00620,map00630,map00640,map00642,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00087,M00088,M00095,M00113,M00373,M00374,M00375	R00238,R00829,R00927,R01177,R03778,R03858,R03991,R04546,R04742,R04747,R05506,R05586,R07891,R07895,R07899,R08091,R08095	RC00004,RC00326,RC00405,RC01702,RC02728,RC02898,RC02955	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_7181113_1	1229780.BN381_70027	3.162e-215	686.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,3UX6T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	AMP-binding enzyme	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding
BYD2_k127_7181113_8	1121272.KB903251_gene746	1.13e-16	91.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	PQQ_2,Sigma70_r2,Sigma70_r4_2
BYD2_k127_7181113_7	1343740.M271_15970	2.794e-24	109.0	COG0776@1|root,COG0776@2|Bacteria,2GV0M@201174|Actinobacteria	201174|Actinobacteria	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006355,GO:0006725,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010106,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019725,GO:0030003,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0040007,GO:0042262,GO:0042592,GO:0042594,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046916,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0060255,GO:0065007,GO:0065008,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090143,GO:0090304,GO:0097100,GO:0097159,GO:0098771,GO:0140110,GO:1901360,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
BYD2_k127_7181113_3	1229780.BN381_180020	1.044e-197	637.0	COG1061@1|root,COG1061@2|Bacteria,2GIU5@201174|Actinobacteria,3UW9B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Type III restriction enzyme, res subunit	sdrA	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ResIII
BYD2_k127_7181113_6	1123261.AXDW01000007_gene2391	4.857e-37	161.0	COG0073@1|root,COG0073@2|Bacteria,1RGU7@1224|Proteobacteria,1S6NH@1236|Gammaproteobacteria,1X7AS@135614|Xanthomonadales	135614|Xanthomonadales	J	Putative tRNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	tRNA_bind
BYD2_k127_7181113_0	103733.JNYO01000003_gene8218	5.388e-272	849.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4E01V@85010|Pseudonocardiales	201174|Actinobacteria	V	ABC-type multidrug transport system, ATPase and permease	-	-	-	ko:K06147,ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1,3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_7181113_2	1380356.JNIK01000004_gene91	6.633e-203	640.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
BYD2_k127_7192896_14	1120950.KB892810_gene7230	6.106e-36	138.0	COG2267@1|root,COG2267@2|Bacteria,2I1RU@201174|Actinobacteria,4DR9Z@85009|Propionibacteriales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_7192896_17	979556.MTES_3300	9.921e-14	79.0	2E4AX@1|root,32Z6K@2|Bacteria,2I15G@201174|Actinobacteria,4FQ9B@85023|Microbacteriaceae	201174|Actinobacteria	S	Domain of unknown function (DUF2017)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2017
BYD2_k127_7192896_15	351607.Acel_1691	1.363e-35	138.0	COG2127@1|root,COG2127@2|Bacteria,2IQ3Z@201174|Actinobacteria,4ESZD@85013|Frankiales	201174|Actinobacteria	S	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation	clpS	-	-	ko:K06891	-	-	-	-	ko00000	-	-	-	ClpS
BYD2_k127_7192896_11	222534.KB893783_gene5258	5.197e-54	201.0	COG1612@1|root,COG1612@2|Bacteria,2GJQX@201174|Actinobacteria,4ESN0@85013|Frankiales	201174|Actinobacteria	O	cytochrome oxidase assembly	ctaA	-	-	ko:K02259	ko00190,ko00860,ko01100,ko01110,ko02020,ko04714,map00190,map00860,map01100,map01110,map02020,map04714	M00154	R07412	RC00769	ko00000,ko00001,ko00002,ko03029	3.D.4.4	-	-	COX15-CtaA
BYD2_k127_7192896_3	1229780.BN381_450058	7.475e-109	364.0	COG0109@1|root,COG0109@2|Bacteria,2GJMY@201174|Actinobacteria,3UWHG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	O	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group	ctaB	GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0030312,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	2.5.1.141	ko:K02257	ko00190,ko00860,ko01100,ko01110,ko04714,map00190,map00860,map01100,map01110,map04714	M00154	R07411	RC01786	ko00000,ko00001,ko00002,ko01000,ko01006,ko03029	-	-	-	UbiA
BYD2_k127_7192896_9	1313172.YM304_38710	2.042e-63	238.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,4CMUD@84992|Acidimicrobiia	2|Bacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.10.3.10	ko:K02298	ko00190,ko01100,map00190,map01100	M00417	R11335	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.4.5	-	-	COX1
BYD2_k127_7192896_16	1229780.BN381_450056	2.599e-21	110.0	COG1845@1|root,COG1845@2|Bacteria,2HDD0@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.6	-	-	COX3
BYD2_k127_7192896_13	1229780.BN381_450055	4.681e-37	151.0	2FBCP@1|root,343IH@2|Bacteria,2H8EE@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7192896_5	1229780.BN381_450054	2.091e-89	314.0	COG1622@1|root,COG1622@2|Bacteria,2GNXA@201174|Actinobacteria,3UWMS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B)	ctaC	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494	1.9.3.1	ko:K02275	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.4,3.D.4.6	-	-	COX2,COX2_TM
BYD2_k127_7192896_0	1229780.BN381_450053	9.524e-292	913.0	COG0843@1|root,COG0843@2|Bacteria,2GJHX@201174|Actinobacteria,3UWD2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B	-	-	1.9.3.1	ko:K02274,ko:K15408	ko00190,ko01100,map00190,map01100	M00155	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.2,3.D.4.3,3.D.4.4,3.D.4.6	-	-	COX1,Cyt_c_ox_IV
BYD2_k127_7192896_8	1313172.YM304_38660	6.905e-80	274.0	COG1845@1|root,COG1845@2|Bacteria,2GKK8@201174|Actinobacteria,4CNAV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cytochrome c oxidase subunit III	-	-	1.9.3.1	ko:K02276,ko:K02299	ko00190,ko01100,map00190,map01100	M00155,M00417	R00081	RC00016	ko00000,ko00001,ko00002,ko01000	3.D.4.4,3.D.4.5,3.D.4.6	-	-	COX3
BYD2_k127_7192896_18	1382356.JQMP01000004_gene57	1.099e-11	70.0	2EKS3@1|root,33EFV@2|Bacteria,2GBBM@200795|Chloroflexi,27YP9@189775|Thermomicrobia	189775|Thermomicrobia	S	Prokaryotic Cytochrome C oxidase subunit IV	-	-	1.9.3.1	ko:K02277	ko00190,ko01100,map00190,map01100	M00155	-	-	ko00000,ko00001,ko00002,ko01000	3.D.4.4	-	-	COX4_pro
BYD2_k127_7192896_6	1313172.YM304_38640	1.1e-84	290.0	COG3336@1|root,COG3336@2|Bacteria,2HG9Q@201174|Actinobacteria,4CN83@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG)	-	-	-	ko:K02862	-	-	-	-	ko00000	-	-	-	Caa3_CtaG
BYD2_k127_7192896_10	106370.Francci3_1654	2.899e-56	220.0	COG0842@1|root,COG0842@2|Bacteria,2GN6S@201174|Actinobacteria,4ESTT@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_3
BYD2_k127_7192896_7	1229780.BN381_450049	4.304e-82	294.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,3UX8B@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	drrA_2	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_7192896_2	1229780.BN381_450047	8.348e-154	499.0	COG0172@1|root,COG0172@2|Bacteria,2GIWP@201174|Actinobacteria,3UWDU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)	serS	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
BYD2_k127_7192896_12	928724.SacglDRAFT_02345	1.532e-38	149.0	COG0735@1|root,COG0735@2|Bacteria,2IFHB@201174|Actinobacteria,4E3EB@85010|Pseudonocardiales	201174|Actinobacteria	P	Belongs to the Fur family	-	-	-	ko:K03711,ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
BYD2_k127_7192896_1	298653.Franean1_0113	1.801e-278	887.0	COG1033@1|root,COG1033@2|Bacteria,2I731@201174|Actinobacteria	201174|Actinobacteria	S	MMPL family	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_7192896_4	1229780.BN381_300041	3.13e-94	316.0	COG1125@1|root,COG1125@2|Bacteria,2GJHI@201174|Actinobacteria,3UX10@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K05847	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	ABC_tran
BYD2_k127_7202695_56	1380356.JNIK01000015_gene2514	1.625e-24	119.0	COG3103@1|root,COG5479@1|root,COG4991@2|Bacteria,COG5479@2|Bacteria,2GN2D@201174|Actinobacteria,4EX5K@85013|Frankiales	201174|Actinobacteria	M	LGFP repeat	-	-	-	-	-	-	-	-	-	-	-	-	LGFP
BYD2_k127_7202695_37	857293.CAAU_0612	1.824e-64	243.0	COG4870@1|root,COG4870@2|Bacteria,1TS2S@1239|Firmicutes,248FU@186801|Clostridia,36EP3@31979|Clostridiaceae	186801|Clostridia	O	Repeat of unknown function (DUF346)	-	-	-	-	-	-	-	-	-	-	-	-	DUF346
BYD2_k127_7202695_19	1313172.YM304_26410	3.775e-136	479.0	COG2256@1|root,COG2256@2|Bacteria,2GKDP@201174|Actinobacteria,4CMYY@84992|Acidimicrobiia	84992|Acidimicrobiia	O	MgsA AAA+ ATPase C terminal	-	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA_assoc_2,MgsA_C,RuvB_N
BYD2_k127_7202695_6	477641.MODMU_2959	4.128e-240	766.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria	201174|Actinobacteria	P	Pfam Sulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
BYD2_k127_7202695_66	1501391.LG35_04200	1.398e-06	59.0	2DQYN@1|root,32UQ2@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7202695_32	1118054.CAGW01000005_gene3791	1.905e-84	295.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,4HANQ@91061|Bacilli,26QYR@186822|Paenibacillaceae	91061|Bacilli	H	Glutamate-1-semialdehyde aminotransferase	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
BYD2_k127_7202695_61	1116232.AHBF01000137_gene1909	5.583e-19	98.0	COG0642@1|root,COG2508@1|root,COG2205@2|Bacteria,COG2508@2|Bacteria,2I8QG@201174|Actinobacteria	201174|Actinobacteria	T	Domain of unknown function (DUF4118)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4118
BYD2_k127_7202695_27	1229780.BN381_130212	6.492e-95	341.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,3UWH9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_7202695_2	1229780.BN381_130211	0.0	1018.0	COG0642@1|root,COG2205@2|Bacteria,2HFQ8@201174|Actinobacteria,3UXJT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BYD2_k127_7202695_42	1229780.BN381_130210	6.302e-55	220.0	COG2156@1|root,COG2156@2|Bacteria,2GK75@201174|Actinobacteria	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
BYD2_k127_7202695_1	1229780.BN381_130209	0.0	1022.0	COG2216@1|root,COG2216@2|Bacteria	2|Bacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
BYD2_k127_7202695_5	1229780.BN381_130208	6.227e-271	843.0	COG2060@1|root,COG2060@2|Bacteria,2GK51@201174|Actinobacteria	201174|Actinobacteria	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
BYD2_k127_7202695_41	1229780.BN381_110015	1.322e-55	208.0	COG5592@1|root,COG5592@2|Bacteria,2IGW0@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
BYD2_k127_7202695_43	644966.Tmar_0770	1.409e-51	192.0	COG2259@1|root,COG2259@2|Bacteria,1V4ER@1239|Firmicutes,24EBI@186801|Clostridia	186801|Clostridia	S	PFAM DoxX	-	-	1.8.5.2	ko:K16937	ko00920,ko01120,map00920,map01120	-	R07177	-	ko00000,ko00001,ko01000	3.D.4.9	-	-	DoxX
BYD2_k127_7202695_46	743718.Isova_0033	3.6e-40	157.0	COG4244@1|root,COG4244@2|Bacteria,2I2FH@201174|Actinobacteria,4F5NA@85017|Promicromonosporaceae	201174|Actinobacteria	S	Predicted membrane protein (DUF2231)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2231
BYD2_k127_7202695_3	1122138.AQUZ01000002_gene2100	7.086e-316	981.0	COG2217@1|root,COG2217@2|Bacteria,2GIRF@201174|Actinobacteria,4DQ5C@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
BYD2_k127_7202695_9	1449353.JQMQ01000005_gene25	2.763e-177	568.0	COG0702@1|root,COG0702@2|Bacteria,2GIZA@201174|Actinobacteria,2NGHW@228398|Streptacidiphilus	201174|Actinobacteria	GM	Protein of unknown function (DUF2867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867,NAD_binding_10
BYD2_k127_7202695_22	1229780.BN381_310034	6.629e-122	411.0	COG0415@1|root,COG0415@2|Bacteria,2GJXU@201174|Actinobacteria,3UWGU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA photolyase	phr	-	4.1.99.3	ko:K01669	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_photolyase,FAD_binding_7
BYD2_k127_7202695_47	1313172.YM304_40290	1.462e-37	151.0	COG1595@1|root,COG1595@2|Bacteria,2IKQ7@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	litS	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_7202695_55	1123251.ATWM01000001_gene602	6.623e-26	115.0	COG5343@1|root,COG5343@2|Bacteria,2IM7X@201174|Actinobacteria,4FHJ6@85021|Intrasporangiaceae	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
BYD2_k127_7202695_58	298653.Franean1_1601	4.021e-22	107.0	COG1595@1|root,COG1595@2|Bacteria,2GP2X@201174|Actinobacteria,4EWE2@85013|Frankiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7202695_11	1452536.JARE01000047_gene2755	3.177e-172	552.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4FMPB@85023|Microbacteriaceae	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28	ko:K01593	ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko04726,ko04728,ko05030,ko05031,ko05034,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
BYD2_k127_7202695_62	1306174.JODP01000028_gene180	3.885e-10	64.0	COG4683@1|root,COG4683@2|Bacteria,2IFY3@201174|Actinobacteria	201174|Actinobacteria	S	Phage derived protein Gp49-like (DUF891)	-	-	-	-	-	-	-	-	-	-	-	-	Gp49
BYD2_k127_7202695_63	479432.Sros_8282	4.754e-09	62.0	COG3620@1|root,COG3620@2|Bacteria,2IKRP@201174|Actinobacteria,4EQNQ@85012|Streptosporangiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BYD2_k127_7202695_57	929712.KI912613_gene2799	5.741e-23	109.0	2DP3D@1|root,330CN@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7202695_7	1449069.JMLO01000016_gene3381	1.537e-214	692.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4FUJ9@85025|Nocardiaceae	201174|Actinobacteria	E	DegT/DnrJ/EryC1/StrS aminotransferase family	aspC	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	2.6.1.1,2.6.1.2,2.6.1.66	ko:K00812,ko:K14260	ko00220,ko00250,ko00270,ko00290,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00290,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00258,R00355,R00694,R00734,R00896,R01215,R02433,R02619,R05052	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	iNJ661.Rv0337c	Aminotran_1_2,HTH_3
BYD2_k127_7202695_18	446468.Ndas_1240	1.593e-136	441.0	COG0491@1|root,COG0491@2|Bacteria,2HFVZ@201174|Actinobacteria,4EFG8@85012|Streptosporangiales	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K05555	ko01057,ko01130,map01057,map01130	M00778	R09305	-	ko00000,ko00001,ko00002,ko01000,ko01008	-	-	-	Lactamase_B
BYD2_k127_7202695_21	1123320.KB889562_gene6740	1.617e-125	408.0	COG1024@1|root,COG1024@2|Bacteria,2IAFJ@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_7202695_15	1123320.KB889562_gene6741	8.003e-144	476.0	COG1028@1|root,COG1028@2|Bacteria,2GK20@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_7202695_35	58123.JOFJ01000007_gene530	2.645e-71	247.0	COG0174@1|root,COG0174@2|Bacteria,2IFHQ@201174|Actinobacteria,4EIZ4@85012|Streptosporangiales	201174|Actinobacteria	E	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	DinB_2
BYD2_k127_7202695_44	1089545.KB913037_gene915	3.112e-43	169.0	COG3795@1|root,COG3795@2|Bacteria,2IQXT@201174|Actinobacteria,4E6YP@85010|Pseudonocardiales	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_7202695_10	469383.Cwoe_3324	6.006e-177	575.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4CRBD@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7202695_31	1095767.CAHD01000040_gene1477	1.308e-84	288.0	COG0640@1|root,COG0640@2|Bacteria,2GJT9@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_7202695_34	1304865.JAGF01000001_gene2621	8.43e-75	269.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1,Polyketide_cyc2
BYD2_k127_7202695_17	222534.KB893672_gene2985	1.377e-142	462.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EUYX@85013|Frankiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	drrA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_7202695_24	1169161.KB897738_gene2625	4.625e-106	359.0	COG0842@1|root,COG0842@2|Bacteria,2I5GM@201174|Actinobacteria	201174|Actinobacteria	V	Transport permease protein	drrB	-	-	ko:K01992,ko:K18233	ko02010,map02010	M00254,M00634	-	-	ko00000,ko00001,ko00002,ko01504,ko02000	3.A.1,3.A.1.105.2	-	-	ABC2_membrane
BYD2_k127_7202695_49	164757.Mjls_2079	3.014e-35	139.0	COG0517@1|root,COG0517@2|Bacteria,2I5AR@201174|Actinobacteria,23F9F@1762|Mycobacteriaceae	201174|Actinobacteria	S	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
BYD2_k127_7202695_23	103733.JNYO01000059_gene8780	4.358e-113	397.0	COG1948@1|root,COG4880@2|Bacteria,2I8JU@201174|Actinobacteria,4E1KA@85010|Pseudonocardiales	201174|Actinobacteria	L	Beta propeller domain	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
BYD2_k127_7202695_26	1380390.JIAT01000010_gene4575	9.297e-98	350.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,4CSGP@84995|Rubrobacteria	84995|Rubrobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
BYD2_k127_7202695_30	1206732.BAGD01000106_gene4696	1.203e-84	302.0	COG1020@1|root,COG1020@2|Bacteria,2GKU0@201174|Actinobacteria,4FXE2@85025|Nocardiaceae	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	2.3.1.20	ko:K00635	ko00561,ko01100,map00561,map01100	M00089	R02251	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	DUF1298,WES_acyltransf
BYD2_k127_7202695_38	234621.RER_34100	5.415e-64	231.0	COG0332@1|root,COG0332@2|Bacteria,2IK61@201174|Actinobacteria,4FXDQ@85025|Nocardiaceae	201174|Actinobacteria	I	synthase III	-	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
BYD2_k127_7202695_13	557599.MKAN_04120	5.77e-151	486.0	COG0332@1|root,COG0332@2|Bacteria,2I9C8@201174|Actinobacteria,23EW9@1762|Mycobacteriaceae	201174|Actinobacteria	I	3-Oxoacyl- acyl-carrier-protein (ACP) synthase III	-	-	2.3.1.180	ko:K00648,ko:K22317	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
BYD2_k127_7202695_12	1449069.JMLO01000001_gene1678	3.241e-166	549.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FX1G@85025|Nocardiaceae	201174|Actinobacteria	P	Sulfate transporter	-	-	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
BYD2_k127_7202695_65	903818.KI912268_gene1333	1.368e-06	60.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2,LigT_PEase
BYD2_k127_7202695_4	448385.sce4570	7.242e-306	959.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1MU0R@1224|Proteobacteria,42MW3@68525|delta/epsilon subdivisions,2WJRZ@28221|Deltaproteobacteria,2YW7G@29|Myxococcales	28221|Deltaproteobacteria	H	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate	ppsA	-	2.7.9.2	ko:K01007	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,map00620,map00680,map00720,map01100,map01120,map01200	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	iAF987.Gmet_2101	PEP-utilizers,PEP-utilizers_C,PPDK_N
BYD2_k127_7202695_54	298655.KI912266_gene6084	8.565e-27	120.0	COG5401@1|root,COG5401@2|Bacteria,2H4HT@201174|Actinobacteria	201174|Actinobacteria	S	Immunoglobulin-like domain of bacterial spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane,Gmad2
BYD2_k127_7202695_59	479434.Sthe_2667	4.805e-21	104.0	COG0589@1|root,COG0589@2|Bacteria,2G768@200795|Chloroflexi	200795|Chloroflexi	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
BYD2_k127_7202695_40	1121924.ATWH01000007_gene1993	2.02e-57	209.0	COG1718@1|root,COG1718@2|Bacteria,2GM3J@201174|Actinobacteria,4FN3V@85023|Microbacteriaceae	201174|Actinobacteria	DT	RIO1 family	-	-	2.7.11.1	ko:K07178	ko03008,map03008	-	-	-	ko00000,ko00001,ko01000,ko01001,ko03009	-	-	-	RIO1
BYD2_k127_7202695_50	1048339.KB913029_gene993	8.918e-31	135.0	COG0517@1|root,COG0517@2|Bacteria,2GKSH@201174|Actinobacteria,4ETKN@85013|Frankiales	201174|Actinobacteria	C	PFAM CBS domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	BON,CBS
BYD2_k127_7202695_16	1313172.YM304_28400	1.171e-142	467.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GMJ4@201174|Actinobacteria	201174|Actinobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
BYD2_k127_7202695_53	1229780.BN381_100065	6.824e-29	121.0	COG3467@1|root,COG3467@2|Bacteria,2HX22@201174|Actinobacteria,3UXG8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
BYD2_k127_7202695_20	1283283.ATXA01000008_gene2989	2.58e-132	433.0	COG2141@1|root,COG2141@2|Bacteria,2H0K9@201174|Actinobacteria	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_7202695_60	471852.Tcur_2353	3.78e-20	94.0	COG0346@1|root,COG0346@2|Bacteria	2|Bacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_7202695_29	58123.JOFJ01000026_gene2762	3.604e-87	295.0	COG2197@1|root,COG2197@2|Bacteria,2GK4B@201174|Actinobacteria,4EIAM@85012|Streptosporangiales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_7202695_14	1089544.KB912942_gene1606	1.867e-145	482.0	COG0645@1|root,COG2187@1|root,COG0645@2|Bacteria,COG2187@2|Bacteria,2GM3U@201174|Actinobacteria,4E8B0@85010|Pseudonocardiales	201174|Actinobacteria	S	AAA domain	-	-	-	ko:K07028	-	-	-	-	ko00000	-	-	-	AAA_33,APH
BYD2_k127_7202695_48	2074.JNYD01000002_gene5605	6.104e-36	145.0	COG3467@1|root,COG3467@2|Bacteria,2GQIA@201174|Actinobacteria	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
BYD2_k127_7202695_52	28444.JODQ01000009_gene3703	5.721e-29	126.0	COG3467@1|root,COG3467@2|Bacteria,2IQ9Y@201174|Actinobacteria,4EJNW@85012|Streptosporangiales	201174|Actinobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
BYD2_k127_7202695_45	570268.ANBB01000088_gene171	3.039e-42	168.0	COG0589@1|root,COG0589@2|Bacteria,2GMFE@201174|Actinobacteria,4EJD9@85012|Streptosporangiales	201174|Actinobacteria	T	Universal stress protein family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
BYD2_k127_7202695_67	1354722.JQLS01000008_gene2052	4.417e-06	56.0	COG2905@1|root,COG2905@2|Bacteria,1MW8U@1224|Proteobacteria,2TRZC@28211|Alphaproteobacteria,46NNU@74030|Roseovarius	28211|Alphaproteobacteria	T	containing cAMP-binding and CBS	-	-	-	ko:K07182	-	-	-	-	ko00000	-	-	-	CBS,DUF294,DUF294_C,cNMP_binding
BYD2_k127_7202695_8	477641.MODMU_2528	4.788e-183	588.0	COG2909@1|root,COG2909@2|Bacteria,2I3S2@201174|Actinobacteria,4EUC0@85013|Frankiales	201174|Actinobacteria	K	Transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BYD2_k127_7202695_33	448385.sce2876	2.795e-82	297.0	COG1960@1|root,COG1960@2|Bacteria,1MXMQ@1224|Proteobacteria,438I3@68525|delta/epsilon subdivisions,2X3T0@28221|Deltaproteobacteria,2YX1B@29|Myxococcales	28221|Deltaproteobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	1.14.13.235	ko:K22027	-	-	-	-	ko00000,ko01000	-	-	-	Acyl-CoA_dh_2,Acyl-CoA_dh_N
BYD2_k127_7202695_0	404589.Anae109_0406	0.0	1261.0	COG1201@1|root,COG1201@2|Bacteria,1MUSW@1224|Proteobacteria,42Q75@68525|delta/epsilon subdivisions,2WMDY@28221|Deltaproteobacteria,2YUG7@29|Myxococcales	28221|Deltaproteobacteria	L	DEAD/H associated	lhr1	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
BYD2_k127_7202695_28	1123023.JIAI01000001_gene6175	1.671e-87	330.0	COG2513@1|root,COG2513@2|Bacteria,2GMQ4@201174|Actinobacteria,4E188@85010|Pseudonocardiales	201174|Actinobacteria	G	Phosphoenolpyruvate phosphomutase	-	-	-	-	-	-	-	-	-	-	-	-	PEP_mutase
BYD2_k127_7202695_64	83332.Rv2829c	5.924e-09	63.0	COG3744@1|root,COG3744@2|Bacteria	2|Bacteria	S	ribonuclease activity	-	GO:0005575,GO:0005576,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113	-	-	-	-	-	-	-	-	-	-	PIN
BYD2_k127_7202695_39	1137269.AZWL01000001_gene5563	5.717e-62	244.0	COG2128@1|root,COG2128@2|Bacteria,2IB85@201174|Actinobacteria	201174|Actinobacteria	S	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_7202695_51	298655.KI912266_gene1059	9.562e-30	124.0	COG1846@1|root,COG1846@2|Bacteria,2IFQ9@201174|Actinobacteria,4ET3M@85013|Frankiales	201174|Actinobacteria	K	PFAM regulatory protein, MarR	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
BYD2_k127_7202695_25	1229780.BN381_130130	1.31e-100	348.0	COG0477@1|root,COG0477@2|Bacteria,2GK06@201174|Actinobacteria,3UWB0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	U	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_3
BYD2_k127_7202695_36	1048339.KB913029_gene4145	2.967e-66	235.0	28HG7@1|root,32T0H@2|Bacteria,2IFQ1@201174|Actinobacteria,4EVYV@85013|Frankiales	201174|Actinobacteria	S	DinB superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_7223481_0	1313172.YM304_37250	6.943e-73	249.0	2B3JS@1|root,31W90@2|Bacteria,2GP1G@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7223481_3	1313172.YM304_37260	1.111e-17	88.0	COG3794@1|root,COG3794@2|Bacteria,2HH58@201174|Actinobacteria,4CP4V@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Cupredoxin-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupredoxin_1
BYD2_k127_7223481_1	1961.JOAK01000027_gene2508	3.67e-42	176.0	COG4315@1|root,COG4315@2|Bacteria,2GNDV@201174|Actinobacteria	201174|Actinobacteria	S	Secreted repeat of unknown function	-	-	-	-	-	-	-	-	-	-	-	-	Lipoprotein_15
BYD2_k127_7223481_2	298655.KI912266_gene2716	1.929e-18	84.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EU2D@85013|Frankiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7224296_0	266117.Rxyl_2529	1.584e-204	648.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
BYD2_k127_7236554_2	1229780.BN381_250081	4.919e-91	302.0	COG0535@1|root,COG0535@2|Bacteria,2GNSY@201174|Actinobacteria	201174|Actinobacteria	C	Radical SAM	pqqE	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM,SPASM
BYD2_k127_7236554_1	298655.KI912266_gene2260	1.323e-206	667.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GMB6@201174|Actinobacteria	201174|Actinobacteria	C	NADH flavin oxidoreductase NADH oxidase	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	NAD_binding_8,Oxidored_FMN,Pyr_redox,Pyr_redox_2
BYD2_k127_7236554_0	882083.SacmaDRAFT_1200	4.07e-211	673.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,2GK8E@201174|Actinobacteria,4E0V1@85010|Pseudonocardiales	201174|Actinobacteria	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	1.3.1.34	ko:K00219	-	-	-	-	ko00000,ko01000	-	-	-	FAD_oxidored,Oxidored_FMN,Pyr_redox_2
BYD2_k127_72473_23	656024.FsymDg_0206	1.248e-63	222.0	COG3832@1|root,COG3832@2|Bacteria,2I8ND@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_72473_30	1246995.AFR_17070	2.062e-31	126.0	COG0640@1|root,COG0640@2|Bacteria,2IQ55@201174|Actinobacteria,4DET1@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_72473_3	1476876.JOJO01000032_gene3859	3.719e-159	511.0	COG4312@1|root,COG4312@2|Bacteria,2GN8A@201174|Actinobacteria	201174|Actinobacteria	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
BYD2_k127_72473_27	1463856.JOHY01000028_gene3661	2.86e-41	159.0	COG0346@1|root,COG0346@2|Bacteria,2IQB4@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_72473_21	219305.MCAG_04394	8.383e-67	236.0	COG2186@1|root,COG2186@2|Bacteria,2GJ82@201174|Actinobacteria,4DCCB@85008|Micromonosporales	201174|Actinobacteria	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
BYD2_k127_72473_6	35754.JNYJ01000079_gene4336	1.05e-131	431.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4DDXV@85008|Micromonosporales	201174|Actinobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
BYD2_k127_72473_10	35754.JNYJ01000079_gene4337	1.134e-106	368.0	COG1129@1|root,COG1129@2|Bacteria,2IHB0@201174|Actinobacteria,4DI25@85008|Micromonosporales	201174|Actinobacteria	G	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
BYD2_k127_72473_11	543632.JOJL01000052_gene6488	2.565e-102	355.0	COG1879@1|root,COG1879@2|Bacteria,2HEHI@201174|Actinobacteria,4DH2G@85008|Micromonosporales	201174|Actinobacteria	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
BYD2_k127_72473_1	211114.JOEF01000032_gene1960	3.387e-191	612.0	COG4948@1|root,COG4948@2|Bacteria,2GKSK@201174|Actinobacteria,4DZ8G@85010|Pseudonocardiales	201174|Actinobacteria	M	mandelate racemase muconate lactonizing	-	-	4.2.1.68	ko:K18334	ko00051,ko01120,map00051,map01120	-	R03688	RC00543	ko00000,ko00001,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
BYD2_k127_72473_15	1169161.KB897740_gene2237	7.452e-96	332.0	COG3618@1|root,COG3618@2|Bacteria,2GM2D@201174|Actinobacteria	201174|Actinobacteria	C	amidohydrolase	-	-	-	ko:K07046	ko00051,ko01120,map00051,map01120	-	R10689	RC00537	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
BYD2_k127_72473_2	1463934.JOCF01000023_gene6230	2.36e-182	589.0	COG3875@1|root,COG3875@2|Bacteria,2I9JU@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
BYD2_k127_72473_8	1445613.JALM01000086_gene3319	2.994e-118	391.0	COG0179@1|root,COG0179@2|Bacteria,2GKED@201174|Actinobacteria,4DX97@85010|Pseudonocardiales	201174|Actinobacteria	Q	2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
BYD2_k127_72473_14	467200.ACFA01000841_gene4053	3.547e-98	335.0	COG1028@1|root,COG1028@2|Bacteria,2GK78@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM Short-chain dehydrogenase reductase SDR	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_72473_38	105422.BBPM01000047_gene1710	8.977e-05	49.0	COG1609@1|root,COG1609@2|Bacteria,2GJBJ@201174|Actinobacteria	201174|Actinobacteria	K	lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
BYD2_k127_72473_35	196162.Noca_0205	5.367e-14	84.0	COG1234@1|root,COG1234@2|Bacteria,2HV83@201174|Actinobacteria,4DUS7@85009|Propionibacteriales	201174|Actinobacteria	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
BYD2_k127_72473_39	1120950.KB892708_gene4507	0.0002646	46.0	COG1515@1|root,COG1515@2|Bacteria,2GJEZ@201174|Actinobacteria,4DUVR@85009|Propionibacteriales	201174|Actinobacteria	L	Endonuclease V	nfi	-	3.1.21.7	ko:K05982	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Endonuclease_5
BYD2_k127_72473_9	653045.Strvi_3715	1.272e-117	384.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_72473_17	1123023.JIAI01000003_gene2622	5.094e-85	289.0	COG0702@1|root,COG0702@2|Bacteria,2IG9B@201174|Actinobacteria,4E93Q@85010|Pseudonocardiales	201174|Actinobacteria	GM	epimerase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
BYD2_k127_72473_33	1172179.AUKV01000002_gene568	1.121e-19	94.0	2C114@1|root,32Z2K@2|Bacteria,2GYNF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_72473_26	1121926.AXWO01000008_gene2990	9.356e-51	190.0	COG1309@1|root,COG1309@2|Bacteria,2IE9K@201174|Actinobacteria,4F01I@85014|Glycomycetales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_72473_37	521393.JH806632_gene19	1.003e-05	51.0	COG1131@1|root,COG1131@2|Bacteria,2GKEH@201174|Actinobacteria,4D40D@85005|Actinomycetales	201174|Actinobacteria	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_72473_12	1394178.AWOO02000032_gene4931	1.837e-101	340.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4ENIC@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_72473_18	1394178.AWOO02000032_gene4932	1.25e-83	284.0	COG0842@1|root,COG0842@2|Bacteria,2IHJH@201174|Actinobacteria,4ENXS@85012|Streptosporangiales	201174|Actinobacteria	U	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_72473_36	580332.Slit_2328	4.683e-10	62.0	COG0262@1|root,COG0262@2|Bacteria	2|Bacteria	H	dihydrofolate reductase activity	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_72473_24	1463901.JOIY01000012_gene19	5.912e-61	232.0	COG0510@1|root,COG0510@2|Bacteria,2GMFN@201174|Actinobacteria	201174|Actinobacteria	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_72473_20	298655.KI912266_gene4018	2.687e-69	241.0	COG1309@1|root,COG1309@2|Bacteria,2GYK7@201174|Actinobacteria,4EVP3@85013|Frankiales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_72473_22	298655.KI912266_gene4019	1.173e-65	233.0	COG0346@1|root,COG0346@2|Bacteria,2H5D3@201174|Actinobacteria,4EVI6@85013|Frankiales	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_72473_29	247156.NFA_28900	3.526e-37	148.0	COG1670@1|root,COG1670@2|Bacteria,2IT84@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
BYD2_k127_72473_34	390989.JOEG01000004_gene3892	3.288e-17	85.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DJQG@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_72473_0	1079986.JH164867_gene2680	9.076e-199	657.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,2I2U4@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Trans_reg_C
BYD2_k127_72473_5	1380356.JNIK01000017_gene2797	2.524e-141	472.0	COG0654@1|root,COG0654@2|Bacteria,2I2TH@201174|Actinobacteria,4EXES@85013|Frankiales	201174|Actinobacteria	CH	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
BYD2_k127_72473_13	1380390.JIAT01000010_gene3916	2.064e-99	331.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2HEP3@201174|Actinobacteria,4CTHA@84995|Rubrobacteria	84995|Rubrobacteria	T	low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
BYD2_k127_72473_25	1150398.JIBJ01000012_gene2155	1.003e-53	201.0	COG0346@1|root,COG0346@2|Bacteria,2IKNQ@201174|Actinobacteria	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_72473_7	390989.JOEG01000001_gene5177	1.486e-125	417.0	COG0531@1|root,COG0531@2|Bacteria,2GJ75@201174|Actinobacteria,4D9TG@85008|Micromonosporales	201174|Actinobacteria	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease,AA_permease_2
BYD2_k127_72473_19	644283.Micau_0719	5.256e-75	254.0	COG3832@1|root,COG3832@2|Bacteria,2IG6F@201174|Actinobacteria,4DDM6@85008|Micromonosporales	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_72473_28	644283.Micau_0720	2.431e-39	148.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,4DFMJ@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043254,GO:0044087,GO:0044212,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090034,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_72473_31	593907.Celgi_0520	4.955e-31	130.0	COG1569@1|root,COG1569@2|Bacteria,2IMP1@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	-	-	-	-	-	-	-	-	-	PIN_3
BYD2_k127_72473_32	163908.KB235896_gene3857	4.894e-23	103.0	COG3311@1|root,COG3311@2|Bacteria,1G6I6@1117|Cyanobacteria,1HP3P@1161|Nostocales	1117|Cyanobacteria	K	TIGRFAM DNA binding domain, excisionase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
BYD2_k127_72473_40	143224.JQMD01000002_gene3615	0.0006697	45.0	COG5434@1|root,COG5434@2|Bacteria,4NDWX@976|Bacteroidetes,1HZRR@117743|Flavobacteriia	976|Bacteroidetes	M	Parallel beta-helix repeats	glaB	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
BYD2_k127_72473_4	526225.Gobs_2317	5.398e-156	498.0	COG3938@1|root,COG3938@2|Bacteria,2GM47@201174|Actinobacteria,4EUM0@85013|Frankiales	201174|Actinobacteria	E	Proline racemase	-	-	5.1.1.4	ko:K01777	ko00330,ko01100,map00330,map01100	-	R01255	RC00479	ko00000,ko00001,ko01000	-	-	-	Pro_racemase
BYD2_k127_72473_16	35754.JNYJ01000100_gene8984	1.843e-92	318.0	COG2423@1|root,COG2423@2|Bacteria,2GJ0U@201174|Actinobacteria,4DD2C@85008|Micromonosporales	201174|Actinobacteria	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
BYD2_k127_7256515_2	1283283.ATXA01000024_gene208	2.375e-163	524.0	COG1960@1|root,COG1960@2|Bacteria	2|Bacteria	I	acyl-CoA dehydrogenase activity	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7256515_4	543728.Vapar_3549	5.117e-115	412.0	COG0457@1|root,COG2197@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2197@2|Bacteria,COG3899@2|Bacteria,1MUDT@1224|Proteobacteria,2VPH8@28216|Betaproteobacteria,4AF3Y@80864|Comamonadaceae	28216|Betaproteobacteria	K	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD
BYD2_k127_7256515_7	543728.Vapar_3546	2.29e-32	127.0	2AGAH@1|root,316G1@2|Bacteria,1N2FZ@1224|Proteobacteria,2WDAY@28216|Betaproteobacteria,4AIKB@80864|Comamonadaceae	28216|Betaproteobacteria	S	Protein of unknown function (DUF4242)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4242
BYD2_k127_7256515_1	106370.Francci3_2165	3.265e-246	769.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4ERZH@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_7256515_5	1123024.AUII01000006_gene4591	1.134e-82	291.0	COG0583@1|root,COG0583@2|Bacteria,2I8WJ@201174|Actinobacteria,4E184@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BYD2_k127_7256515_3	1123024.AUII01000006_gene4590	1.146e-123	407.0	COG1319@1|root,COG1319@2|Bacteria,2GT14@201174|Actinobacteria,4DXFH@85010|Pseudonocardiales	201174|Actinobacteria	C	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM	-	-	1.2.5.3	ko:K03519	-	-	R11168	RC02800	ko00000,ko01000	-	-	iNJ661.Rv0375c	CO_deh_flav_C,FAD_binding_5
BYD2_k127_7256515_6	1246448.ANAZ01000040_gene509	1.504e-78	269.0	COG2080@1|root,COG2080@2|Bacteria,2GK8J@201174|Actinobacteria,4EITW@85012|Streptosporangiales	201174|Actinobacteria	C	[2Fe-2S] binding domain	coxS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	iNJ661.Rv0374c	Fer2,Fer2_2
BYD2_k127_7256515_0	1157637.KB892124_gene790	1.379e-284	889.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
BYD2_k127_7261461_1	1123023.JIAI01000017_gene3546	3.036e-116	383.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria,4E8XM@85010|Pseudonocardiales	201174|Actinobacteria	K	SnoaL-like domain	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_7261461_3	948106.AWZT01000018_gene4708	4.814e-80	271.0	COG4312@1|root,COG4312@2|Bacteria,1NAXN@1224|Proteobacteria,2VPP0@28216|Betaproteobacteria,1K047@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Bacterial protein of unknown function (DUF899)	-	-	-	-	-	-	-	-	-	-	-	-	DUF899
BYD2_k127_7261461_8	1464048.JNZS01000029_gene1746	4.147e-47	173.0	COG3744@1|root,COG3744@2|Bacteria,2GSS6@201174|Actinobacteria,4DEE8@85008|Micromonosporales	201174|Actinobacteria	S	PFAM PilT protein domain protein	-	-	-	-	-	-	-	-	-	-	-	-	PIN
BYD2_k127_7261461_13	1120949.KB903323_gene3239	3.563e-30	121.0	COG4118@1|root,COG4118@2|Bacteria,2IQGB@201174|Actinobacteria,4DFZS@85008|Micromonosporales	201174|Actinobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
BYD2_k127_7261461_14	1122138.AQUZ01000036_gene5415	8.647e-07	57.0	291ZT@1|root,2ZPJ4@2|Bacteria,2GR7R@201174|Actinobacteria,4DQTI@85009|Propionibacteriales	201174|Actinobacteria	S	Protein of unknown function (DUF2587)	bpa	GO:0000502,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010604,GO:0016020,GO:0016043,GO:0019222,GO:0022607,GO:0022624,GO:0030162,GO:0030312,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0032268,GO:0032270,GO:0032991,GO:0042176,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0044877,GO:0045732,GO:0045862,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0060255,GO:0061136,GO:0065003,GO:0065007,GO:0070628,GO:0071840,GO:0071944,GO:0080090,GO:1901800,GO:1902494,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1905368,GO:1905369	-	-	-	-	-	-	-	-	-	-	DUF2587
BYD2_k127_7261461_2	1229780.BN381_40079	2.818e-81	281.0	COG2135@1|root,COG2135@2|Bacteria,2GKY8@201174|Actinobacteria,3UWQB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
BYD2_k127_7261461_6	1305732.JAGG01000001_gene2114	5.774e-52	187.0	COG0537@1|root,COG0537@2|Bacteria,2IKWU@201174|Actinobacteria,4FSI4@85023|Microbacteriaceae	201174|Actinobacteria	FG	Scavenger mRNA decapping enzyme C-term binding	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
BYD2_k127_7261461_4	1313172.YM304_25680	1.083e-54	198.0	COG0558@1|root,COG0558@2|Bacteria,2GM3F@201174|Actinobacteria,4CN98@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
BYD2_k127_7261461_0	1463887.KL589951_gene4851	2.105e-250	799.0	COG1109@1|root,COG1208@1|root,COG1109@2|Bacteria,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria	201174|Actinobacteria	JM	Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits	-	-	2.7.7.13,5.4.2.8	ko:K16881	ko00051,ko00520,ko01100,ko01110,ko01130,map00051,map00520,map01100,map01110,map01130	M00114,M00362	R00885,R01818	RC00002,RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase,PGM_PMM_I,PGM_PMM_II,PGM_PMM_III
BYD2_k127_7261461_9	1122182.KB903836_gene5128	2.192e-46	170.0	COG0509@1|root,COG0509@2|Bacteria,2IKN2@201174|Actinobacteria,4DE4E@85008|Micromonosporales	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein	gcvH	-	-	ko:K02437	ko00260,ko00630,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map01100,map01110,map01130,map01200	M00532	R01221	RC00022,RC02834	ko00000,ko00001,ko00002	-	-	iNJ661.Rv1826	GCV_H
BYD2_k127_7261461_10	469371.Tbis_1693	6.662e-46	170.0	COG1716@1|root,COG1716@2|Bacteria,2GK99@201174|Actinobacteria,4E2ZJ@85010|Pseudonocardiales	201174|Actinobacteria	T	(FHA) domain	garA	-	-	-	-	-	-	-	-	-	-	-	FHA,Yop-YscD_cpl,zinc_ribbon_2
BYD2_k127_7261461_7	1313172.YM304_25710	1.133e-49	196.0	COG0789@1|root,COG0789@2|Bacteria,2HBV6@201174|Actinobacteria,4CN7E@84992|Acidimicrobiia	84992|Acidimicrobiia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
BYD2_k127_7261461_12	1313172.YM304_25720	6.588e-39	153.0	COG1259@1|root,COG1259@2|Bacteria,2GN26@201174|Actinobacteria,4CN3Y@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Bifunctional nuclease	-	-	-	ko:K08999	-	-	-	-	ko00000	-	-	-	DNase-RNase
BYD2_k127_7261461_5	1229780.BN381_40086	3.744e-52	189.0	COG0789@1|root,COG0789@2|Bacteria,2GM67@201174|Actinobacteria,3UWPC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	merR2	-	-	-	-	-	-	-	-	-	-	-	MerR_1
BYD2_k127_7261461_11	1229780.BN381_40087	5.336e-42	165.0	COG0404@1|root,COG0404@2|Bacteria,2GJ47@201174|Actinobacteria,3UWIC@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	The glycine cleavage system catalyzes the degradation of glycine	gcvT	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944	2.1.2.10	ko:K00605	ko00260,ko00630,ko00670,ko01100,ko01110,ko01130,ko01200,map00260,map00630,map00670,map01100,map01110,map01130,map01200	M00532	R01221,R02300,R04125	RC00022,RC00069,RC00183,RC02834	ko00000,ko00001,ko00002,ko01000	-	-	-	GCV_T,GCV_T_C
BYD2_k127_7280038_7	1123250.KB908379_gene1163	1.058e-07	56.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,4H4AN@909932|Negativicutes	909932|Negativicutes	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
BYD2_k127_7280038_1	1229780.BN381_90066	2.143e-126	410.0	COG1210@1|root,COG1210@2|Bacteria,2I2EW@201174|Actinobacteria,3UWE1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Nucleotidyl transferase	galU	-	2.7.7.9	ko:K00963	ko00040,ko00052,ko00500,ko00520,ko01100,ko01130,map00040,map00052,map00500,map00520,map01100,map01130	M00129,M00361,M00362,M00549	R00289	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
BYD2_k127_7280038_2	1313172.YM304_11030	6.057e-108	364.0	COG0303@1|root,COG0303@2|Bacteria,2GJC3@201174|Actinobacteria,4CMP8@84992|Acidimicrobiia	84992|Acidimicrobiia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
BYD2_k127_7280038_0	1229780.BN381_90064	4.251e-134	436.0	COG2896@1|root,COG2896@2|Bacteria,2GN0V@201174|Actinobacteria,3UX2T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Molybdenum Cofactor Synthesis C	moaA	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
BYD2_k127_7280038_4	1121877.JQKF01000003_gene1581	3.205e-73	249.0	COG0315@1|root,COG0315@2|Bacteria,2IHR6@201174|Actinobacteria,4CMYS@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
BYD2_k127_7280038_5	1121468.AUBR01000016_gene2323	6.379e-27	125.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24GDU@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
BYD2_k127_7280038_6	1123024.AUII01000010_gene714	1.617e-09	61.0	COG3311@1|root,COG3311@2|Bacteria,2GXIU@201174|Actinobacteria,4E6P6@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
BYD2_k127_7280038_3	1463861.JNXE01000002_gene6513	2.736e-90	301.0	COG1075@1|root,COG1075@2|Bacteria,2I2U3@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_7284140_0	1123023.JIAI01000002_gene5486	1.684e-222	694.0	COG1350@1|root,COG1350@2|Bacteria,2GP7D@201174|Actinobacteria,4DZNN@85010|Pseudonocardiales	201174|Actinobacteria	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB2	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
BYD2_k127_7284140_3	1137268.AZXF01000026_gene2441	1.766e-74	263.0	COG2207@1|root,COG2207@2|Bacteria,2GST6@201174|Actinobacteria,4EJTU@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_7284140_7	446468.Ndas_4530	8.053e-55	212.0	COG1576@1|root,COG1576@2|Bacteria,2I47S@201174|Actinobacteria,4EPWB@85012|Streptosporangiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_7284140_12	29581.BW37_04340	8.326e-45	174.0	COG3832@1|root,COG3832@2|Bacteria,1RDMX@1224|Proteobacteria,2VRWE@28216|Betaproteobacteria,4749B@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_7284140_11	378806.STAUR_7670	1.316e-47	175.0	COG3476@1|root,COG3476@2|Bacteria,1MZC1@1224|Proteobacteria,42VB2@68525|delta/epsilon subdivisions,2WS8S@28221|Deltaproteobacteria,2Z036@29|Myxococcales	28221|Deltaproteobacteria	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
BYD2_k127_7284140_9	1380393.JHVP01000001_gene2633	1.796e-49	195.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria,4ET4R@85013|Frankiales	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
BYD2_k127_7284140_4	1116232.AHBF01000077_gene8091	2.151e-74	253.0	COG1670@1|root,COG1670@2|Bacteria,2IFMK@201174|Actinobacteria	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.57,2.3.1.82	ko:K00657,ko:K00663	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_3,Acetyltransf_8
BYD2_k127_7284140_5	1282876.BAOK01000001_gene1422	5.439e-64	238.0	COG0477@1|root,COG2814@2|Bacteria,1QTY0@1224|Proteobacteria,2TXVS@28211|Alphaproteobacteria	28211|Alphaproteobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,Sugar_tr
BYD2_k127_7284140_10	1380354.JIAN01000005_gene1521	2.602e-49	189.0	COG1470@1|root,COG1470@2|Bacteria,2GP8D@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
BYD2_k127_7284140_1	1380347.JNII01000007_gene187	1.194e-104	362.0	COG0642@1|root,COG0642@2|Bacteria,2I2YP@201174|Actinobacteria	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_7284140_2	1380347.JNII01000007_gene186	6.865e-92	308.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4ETZ6@85013|Frankiales	201174|Actinobacteria	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_7284140_6	1121324.CLIT_2c03230	8.538e-64	233.0	COG2998@1|root,COG2998@2|Bacteria,1V9V8@1239|Firmicutes,25H3U@186801|Clostridia	186801|Clostridia	H	Copper amine oxidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Cu_amine_oxidN1
BYD2_k127_7284140_13	1146883.BLASA_3330	3.572e-23	104.0	2BKPP@1|root,32F5B@2|Bacteria,2GZGW@201174|Actinobacteria	201174|Actinobacteria	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY_2
BYD2_k127_7284140_14	298653.Franean1_6798	0.000792	50.0	COG1073@1|root,COG1073@2|Bacteria	2|Bacteria	S	thiolester hydrolase activity	-	-	-	-	-	-	-	-	-	-	-	-	DLH,DUF1929,Glyoxal_oxid_N
BYD2_k127_7284140_8	1123279.ATUS01000001_gene2396	1.944e-54	199.0	COG5361@1|root,COG5361@2|Bacteria,1NQYA@1224|Proteobacteria,1SJTP@1236|Gammaproteobacteria,1J97U@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	S	Protein of unknown function (DUF1214)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1214
BYD2_k127_7360206_4	369723.Strop_3846	1.243e-47	181.0	COG4213@1|root,COG4213@2|Bacteria,2GKRE@201174|Actinobacteria,4D9NH@85008|Micromonosporales	201174|Actinobacteria	G	ABC-type xylose transport system, periplasmic component	xylF	-	-	ko:K10543	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.4	-	-	Peripla_BP_4
BYD2_k127_7360206_1	1122939.ATUD01000001_gene318	3.638e-106	349.0	COG1129@1|root,COG1129@2|Bacteria,2GJDV@201174|Actinobacteria,4CR9Y@84995|Rubrobacteria	84995|Rubrobacteria	G	ATPases associated with a variety of cellular activities	-	-	3.6.3.17	ko:K10545	ko02010,map02010	M00215	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.4	-	-	ABC_tran
BYD2_k127_7360206_2	1380390.JIAT01000011_gene2450	6.1e-104	363.0	COG4214@1|root,COG4214@2|Bacteria,2GJAH@201174|Actinobacteria,4CS8K@84995|Rubrobacteria	84995|Rubrobacteria	G	Branched-chain amino acid transport system / permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_2
BYD2_k127_7360206_0	926550.CLDAP_27920	3.048e-160	523.0	COG1858@1|root,COG2133@1|root,COG1858@2|Bacteria,COG2133@2|Bacteria,2G989@200795|Chloroflexi	200795|Chloroflexi	C	Di-haem cytochrome c peroxidase	-	-	1.11.1.5	ko:K00428	-	-	-	-	ko00000,ko01000	-	-	-	CCP_MauG
BYD2_k127_7360206_3	243233.MCA2161	2.009e-95	333.0	COG3206@1|root,COG3206@2|Bacteria,1QX0J@1224|Proteobacteria,1RZ5A@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	protein involved in exopolysaccharide biosynthesis	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7403046_2	1463934.JOCF01000061_gene3287	2.452e-123	413.0	COG0583@1|root,COG0657@1|root,COG0583@2|Bacteria,COG0657@2|Bacteria,2I8XP@201174|Actinobacteria	201174|Actinobacteria	I	Alpha beta hydrolase	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3,HTH_1
BYD2_k127_7403046_4	1449347.JQLN01000004_gene6110	3.126e-29	129.0	COG0657@1|root,COG0657@2|Bacteria,2GKX2@201174|Actinobacteria,2M17J@2063|Kitasatospora	201174|Actinobacteria	I	Carboxylesterase family	-	-	-	ko:K01066	-	-	-	-	ko00000,ko01000	-	-	-	Abhydrolase_3
BYD2_k127_7403046_3	862751.SACTE_4153	2.337e-62	234.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	sigG	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	NTF2,Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_7403046_0	1229780.BN381_170037	8.447e-164	532.0	COG0554@1|root,COG0554@2|Bacteria,2GM13@201174|Actinobacteria,3UWF2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
BYD2_k127_7403046_1	1229780.BN381_170035	1.08e-144	469.0	COG0277@1|root,COG0277@2|Bacteria,2GIS6@201174|Actinobacteria	201174|Actinobacteria	C	FAD linked	-	-	2.5.1.26	ko:K00803	ko00565,ko01100,ko04146,map00565,map01100,map04146	-	R04311	RC00020,RC02886	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_742128_4	1957.JODX01000019_gene1528	5.412e-26	108.0	COG1960@1|root,COG1960@2|Bacteria,2GK9U@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_742128_1	287986.DV20_21075	2.777e-45	177.0	COG2318@1|root,COG2318@2|Bacteria,2HRVG@201174|Actinobacteria,4EB71@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_742128_3	1229780.BN381_400047	1.189e-26	124.0	COG1403@1|root,COG1403@2|Bacteria	2|Bacteria	V	endonuclease activity	-	-	-	ko:K07451	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DUF222,HNH,HNH_4
BYD2_k127_742128_2	1303692.SFUL_314	3.533e-40	160.0	COG2334@1|root,COG2334@2|Bacteria,2HCIQ@201174|Actinobacteria	201174|Actinobacteria	M	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_742128_0	2074.JNYD01000023_gene1285	1.041e-93	314.0	COG0212@1|root,COG0212@2|Bacteria,2GM4X@201174|Actinobacteria,4E2I3@85010|Pseudonocardiales	201174|Actinobacteria	H	PFAM 5-formyltetrahydrofolate cyclo-ligase	-	-	6.3.3.2	ko:K01934	ko00670,ko01100,map00670,map01100	-	R02301	RC00183	ko00000,ko00001,ko01000	-	-	-	5-FTHF_cyc-lig
BYD2_k127_742226_15	1101189.AQUO01000002_gene706	1.139e-20	103.0	COG0368@1|root,COG0368@2|Bacteria,1RHCC@1224|Proteobacteria,2U97D@28211|Alphaproteobacteria,2PVT0@265|Paracoccus	28211|Alphaproteobacteria	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
BYD2_k127_742226_13	1120936.KB907210_gene5884	1.314e-31	130.0	COG2087@1|root,COG2087@2|Bacteria,2GM8Q@201174|Actinobacteria,4EIM3@85012|Streptosporangiales	201174|Actinobacteria	H	Cobinamide kinase / cobinamide phosphate guanyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU,Lactamase_B_2
BYD2_k127_742226_12	713587.THITH_07840	5.306e-41	156.0	COG0394@1|root,COG0394@2|Bacteria,1RH90@1224|Proteobacteria,1S5X6@1236|Gammaproteobacteria,1WY50@135613|Chromatiales	135613|Chromatiales	T	low molecular weight	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
BYD2_k127_742226_9	469383.Cwoe_1308	5.139e-69	250.0	COG3001@1|root,COG3001@2|Bacteria,2GW7W@201174|Actinobacteria	201174|Actinobacteria	G	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Fructosamin_kin
BYD2_k127_742226_14	298654.FraEuI1c_4613	1.058e-22	110.0	2CIS7@1|root,2ZTU5@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_742226_10	697282.Mettu_1842	4.124e-67	251.0	COG5607@1|root,COG5607@2|Bacteria,1R5I1@1224|Proteobacteria,1S0QK@1236|Gammaproteobacteria,1XEJ3@135618|Methylococcales	135618|Methylococcales	S	CHAD	-	-	-	-	-	-	-	-	-	-	-	-	CHAD
BYD2_k127_742226_5	1049564.TevJSym_ac01690	9.85e-81	287.0	COG1192@1|root,COG1192@2|Bacteria,1R62T@1224|Proteobacteria,1S58J@1236|Gammaproteobacteria,1JA86@118884|unclassified Gammaproteobacteria	1236|Gammaproteobacteria	D	Cellulose biosynthesis protein BcsQ	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
BYD2_k127_742226_11	232348.ADXL01000034_gene1375	4.899e-58	204.0	COG0229@1|root,COG0229@2|Bacteria,1G5S6@1117|Cyanobacteria,1H0VR@1129|Synechococcus	1117|Cyanobacteria	C	Belongs to the MsrB Met sulfoxide reductase family	msrB	-	1.8.4.12	ko:K07305	-	-	-	-	ko00000,ko01000	-	-	-	SelR
BYD2_k127_742226_1	1120950.KB892707_gene5004	7.567e-156	503.0	COG1362@1|root,COG1362@2|Bacteria,2GKW4@201174|Actinobacteria,4DPTA@85009|Propionibacteriales	201174|Actinobacteria	E	Aminopeptidase I zinc metalloprotease (M18)	apeB	GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
BYD2_k127_742226_3	365528.KB891181_gene4741	1.169e-102	348.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glycos_transf_1,Glycos_transf_2
BYD2_k127_742226_6	1313172.YM304_34920	6.384e-79	269.0	COG4502@1|root,COG4502@2|Bacteria,2IAHF@201174|Actinobacteria	201174|Actinobacteria	S	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)	-	-	-	-	-	-	-	-	-	-	-	-	NT5C
BYD2_k127_742226_0	106370.Francci3_1050	0.0	1111.0	COG1572@1|root,COG1572@2|Bacteria,2I56C@201174|Actinobacteria,4EXBH@85013|Frankiales	201174|Actinobacteria	S	Domain of unknown function (DUF3367)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3367
BYD2_k127_742226_2	1229780.BN381_50074	1.839e-142	466.0	COG0438@1|root,COG0438@2|Bacteria,2GK8D@201174|Actinobacteria,3UXFI@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_742226_7	1229780.BN381_10225	1.268e-77	273.0	COG4122@1|root,COG4122@2|Bacteria,2GQ0Z@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_24
BYD2_k127_742226_8	1313172.YM304_25130	1.823e-72	258.0	COG0463@1|root,COG0463@2|Bacteria,2IPT1@201174|Actinobacteria	201174|Actinobacteria	M	PFAM Glycosyl transferase family 2	-	-	2.4.1.83	ko:K00721	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
BYD2_k127_742226_4	1229780.BN381_310085	1.139e-86	301.0	2EW2W@1|root,33PG5@2|Bacteria,2H27S@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7432887_0	471852.Tcur_1701	0.0	1082.0	COG0525@1|root,COG0525@2|Bacteria,2GK8H@201174|Actinobacteria,4EIDQ@85012|Streptosporangiales	201174|Actinobacteria	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
BYD2_k127_7432887_1	1313172.YM304_22030	4.18e-89	306.0	COG0668@1|root,COG0668@2|Bacteria,2GMFK@201174|Actinobacteria	201174|Actinobacteria	M	mechanosensitive ion channel	mscS	-	-	ko:K22044	-	-	-	-	ko00000,ko02000	1.A.23.3	-	-	MS_channel
BYD2_k127_7432887_2	675635.Psed_0592	5.873e-55	202.0	COG0466@1|root,COG0466@2|Bacteria,2GK9D@201174|Actinobacteria,4DYVW@85010|Pseudonocardiales	201174|Actinobacteria	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
BYD2_k127_7442057_1	1007104.SUS17_1519	5.422e-73	257.0	COG0396@1|root,COG0396@2|Bacteria,1MUGK@1224|Proteobacteria,2TS8T@28211|Alphaproteobacteria,2K0E3@204457|Sphingomonadales	204457|Sphingomonadales	O	ABC-type transport system involved in Fe-S cluster assembly, ATPase component	sufC	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
BYD2_k127_7442057_4	529884.Rhola_00007930	1.095e-19	104.0	COG2146@1|root,COG2146@2|Bacteria,2IQK7@201174|Actinobacteria,4FP2S@85023|Microbacteriaceae	201174|Actinobacteria	P	Rieske-like [2Fe-2S] domain	hcaC	-	-	ko:K05710	ko00360,ko01120,ko01220,map00360,map01120,map01220	M00545	R06782,R06783	RC00098	br01602,ko00000,ko00001,ko00002	-	-	-	Rieske
BYD2_k127_7442057_2	525904.Tter_1697	3.233e-64	236.0	COG0719@1|root,COG0719@2|Bacteria,2NPGC@2323|unclassified Bacteria	2|Bacteria	O	FeS assembly protein SufD	sufD	GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0040007,GO:0043207,GO:0044085,GO:0044237,GO:0044403,GO:0044419,GO:0050896,GO:0051186,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071840,GO:0075136	-	ko:K07033,ko:K09015	-	-	-	-	ko00000	-	-	iB21_1397.B21_01640,iECBD_1354.ECBD_1964,iECB_1328.ECB_01650,iECD_1391.ECD_01650,iUMNK88_1353.UMNK88_2144	UPF0051
BYD2_k127_7442057_3	1229780.BN381_210073	5.149e-39	151.0	2FF8Q@1|root,3476J@2|Bacteria,2H7PN@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7442057_0	525909.Afer_0543	1.729e-117	380.0	COG0719@1|root,COG0719@2|Bacteria,2GKCZ@201174|Actinobacteria,4CMQU@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Uncharacterized protein family (UPF0051)	-	-	-	ko:K09014	-	-	-	-	ko00000	-	-	-	UPF0051
BYD2_k127_7452029_0	1313172.YM304_35830	4.542e-172	559.0	COG0699@1|root,COG0699@2|Bacteria,2GNGP@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Dynamin family	-	-	-	-	-	-	-	-	-	-	-	-	Dynamin_N
BYD2_k127_7452029_2	1123023.JIAI01000005_gene655	1.516e-168	546.0	COG0699@1|root,COG0699@2|Bacteria,2GK6T@201174|Actinobacteria,4DYHH@85010|Pseudonocardiales	201174|Actinobacteria	T	GTPases (dynamin-related)	iniC	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Dynamin_N
BYD2_k127_7452029_3	106370.Francci3_1054	1.825e-90	324.0	COG1835@1|root,COG2755@1|root,COG1835@2|Bacteria,COG2755@2|Bacteria,2GKI5@201174|Actinobacteria	201174|Actinobacteria	I	Acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
BYD2_k127_7452029_1	1229780.BN381_150043	7.253e-172	547.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWCM@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Thiolase, C-terminal domain	fadA4	GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043207,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044403,GO:0044419,GO:0044464,GO:0046395,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:0075136,GO:1901575	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_7452773_2	455632.SGR_6686	4.682e-34	139.0	COG0662@1|root,COG0662@2|Bacteria,2IHQ8@201174|Actinobacteria,41CK0@629295|Streptomyces griseus group	201174|Actinobacteria	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_7452773_0	2002.JOEQ01000028_gene8139	6.049e-223	751.0	COG2197@1|root,COG3903@1|root,COG2197@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EGNR@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,GerE
BYD2_k127_7452773_1	1245475.ANAE01000161_gene850	2.608e-45	179.0	COG1376@1|root,COG1376@2|Bacteria,2INDP@201174|Actinobacteria,4EQW6@85012|Streptosporangiales	201174|Actinobacteria	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
BYD2_k127_7452773_3	585531.HMPREF0063_12015	5.716e-27	128.0	COG1595@1|root,COG1595@2|Bacteria,2GRZW@201174|Actinobacteria,4DSMI@85009|Propionibacteriales	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2
BYD2_k127_7456319_11	345341.KUTG_05877	9.365e-30	118.0	COG0099@1|root,COG0099@2|Bacteria,2IHPN@201174|Actinobacteria,4E3FF@85010|Pseudonocardiales	201174|Actinobacteria	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
BYD2_k127_7456319_8	1229780.BN381_450073	3.595e-60	213.0	COG0100@1|root,COG0100@2|Bacteria,2IFFC@201174|Actinobacteria,3UWJ3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
BYD2_k127_7456319_4	1229780.BN381_450072	1.16e-86	301.0	COG0522@1|root,COG0522@2|Bacteria,2GIRX@201174|Actinobacteria,3UWKS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0016020,GO:0019222,GO:0019843,GO:0030312,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
BYD2_k127_7456319_1	1313172.YM304_08750	6.073e-143	462.0	COG0202@1|root,COG0202@2|Bacteria,2GJJ5@201174|Actinobacteria,4CMSV@84992|Acidimicrobiia	84992|Acidimicrobiia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
BYD2_k127_7456319_10	1313172.YM304_08760	4.097e-46	169.0	COG0203@1|root,COG0203@2|Bacteria,2IHV2@201174|Actinobacteria,4CN4I@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
BYD2_k127_7456319_5	1313172.YM304_08770	1.304e-70	250.0	COG0101@1|root,COG0101@2|Bacteria,2GJ6C@201174|Actinobacteria,4CNBD@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
BYD2_k127_7456319_12	58123.JOFJ01000005_gene1300	1.312e-29	127.0	COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4EHD3@85012|Streptosporangiales	201174|Actinobacteria	I	Lysylphosphatidylglycerol synthase TM region	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
BYD2_k127_7456319_13	710685.MycrhN_2818	8.924e-29	135.0	COG0671@1|root,COG0671@2|Bacteria	2|Bacteria	I	phosphatidate phosphatase activity	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF3703,PAP2
BYD2_k127_7456319_0	1380347.JNII01000005_gene3057	4.024e-174	571.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	-	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	Kdo,PAP2
BYD2_k127_7456319_7	1211815.CBYP010000050_gene561	1.904e-61	223.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4EVAF@85013|Frankiales	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
BYD2_k127_7456319_3	1146883.BLASA_4593	2.039e-95	335.0	COG0392@1|root,COG0392@2|Bacteria,2ICMJ@201174|Actinobacteria,4ETKK@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
BYD2_k127_7456319_2	561175.KB894098_gene5216	4.88e-111	365.0	COG2326@1|root,COG2326@2|Bacteria,2GKRN@201174|Actinobacteria,4EHKK@85012|Streptosporangiales	201174|Actinobacteria	S	Polyphosphate kinase 2 (PPK2)	-	-	2.7.4.1	ko:K22468	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PPK2
BYD2_k127_7456319_6	1313172.YM304_08800	1.174e-62	229.0	COG0102@1|root,COG0102@2|Bacteria,2IFG1@201174|Actinobacteria,4CN26@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
BYD2_k127_7456319_9	1229780.BN381_130024	1.985e-47	182.0	COG0103@1|root,COG0103@2|Bacteria,2GNDY@201174|Actinobacteria,3UWN9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Belongs to the universal ribosomal protein uS9 family	rpsI	GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
BYD2_k127_7456319_14	1121472.AQWN01000001_gene280	3.391e-23	103.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,260XD@186807|Peptococcaceae	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
BYD2_k127_7465414_9	1343740.M271_20320	5.005e-74	257.0	COG0569@1|root,COG0569@2|Bacteria,2IA09@201174|Actinobacteria	201174|Actinobacteria	P	domain protein	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
BYD2_k127_7465414_4	110319.CF8_3203	3.605e-131	460.0	COG0168@1|root,COG0168@2|Bacteria,2GKKS@201174|Actinobacteria,4DNQE@85009|Propionibacteriales	201174|Actinobacteria	P	Cation transport protein	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
BYD2_k127_7465414_12	314278.NB231_03015	2.056e-40	172.0	2C40F@1|root,33WUG@2|Bacteria,1NWBW@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7465414_6	1048339.KB913029_gene3133	1.986e-103	341.0	COG0426@1|root,COG0426@2|Bacteria,2GKJ9@201174|Actinobacteria,4ESHY@85013|Frankiales	201174|Actinobacteria	C	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
BYD2_k127_7465414_1	479435.Kfla_5651	1.423e-185	603.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	AAA_16,BTAD,Pkinase,TPR_12
BYD2_k127_7465414_5	1240349.ANGC01000024_gene3611	3.672e-123	403.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,4FY04@85025|Nocardiaceae	201174|Actinobacteria	S	Patatin-like phospholipase	-	GO:0003674,GO:0003824,GO:0016787	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_7465414_7	298654.FraEuI1c_0982	3.134e-99	349.0	COG1741@1|root,COG1741@2|Bacteria,2GM9P@201174|Actinobacteria,4ETSB@85013|Frankiales	201174|Actinobacteria	S	Belongs to the pirin family	-	-	-	ko:K06911	-	-	-	-	ko00000	-	-	-	Pirin,Pirin_C
BYD2_k127_7465414_2	977880.RALTA_B1144	1.89e-161	527.0	COG0318@1|root,COG0318@2|Bacteria,1MU6G@1224|Proteobacteria,2VPPU@28216|Betaproteobacteria	28216|Betaproteobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BYD2_k127_7465414_10	1123024.AUII01000003_gene3265	1.449e-52	193.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_7465414_11	477641.MODMU_2525	9.613e-42	164.0	COG0596@1|root,COG0596@2|Bacteria,2IKJJ@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_7465414_14	1448389.BAVQ01000003_gene3553	2.832e-29	120.0	COG2149@1|root,COG2149@2|Bacteria,2GQU9@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	ko:K00389	-	-	-	-	ko00000	-	-	-	DUF202
BYD2_k127_7465414_13	1313172.YM304_27870	7.813e-32	142.0	COG0628@1|root,COG0628@2|Bacteria	2|Bacteria	D	permease	perM	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944	-	ko:K03548	-	-	-	-	ko00000,ko02000	2.A.86.1	-	-	AI-2E_transport
BYD2_k127_7465414_8	1313172.YM304_27860	2.118e-78	276.0	COG0628@1|root,COG0628@2|Bacteria,2GN4Y@201174|Actinobacteria,4CNDI@84992|Acidimicrobiia	84992|Acidimicrobiia	S	AI-2E family transporter	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
BYD2_k127_7465414_0	1313172.YM304_13290	9.001e-224	697.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7465414_3	471852.Tcur_2652	6.022e-149	478.0	COG3173@1|root,COG3173@2|Bacteria,2GJT0@201174|Actinobacteria,4EHYK@85012|Streptosporangiales	201174|Actinobacteria	S	Ecdysteroid kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_746758_3	504472.Slin_3264	1.396e-07	56.0	COG0262@1|root,COG0262@2|Bacteria,4NSY9@976|Bacteroidetes,47XF5@768503|Cytophagia	976|Bacteroidetes	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_746758_2	1304865.JAGF01000001_gene2884	1.097e-15	90.0	COG5602@1|root,COG5602@2|Bacteria	2|Bacteria	B	histone deacetylation	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_746758_1	870187.Thini_1988	4.711e-38	160.0	COG3170@1|root,COG3170@2|Bacteria	2|Bacteria	NU	translation initiation factor activity	-	-	-	-	-	-	-	-	-	-	-	-	DUF1631,DUF2510,PknH_C,TIR_2
BYD2_k127_746758_0	591158.SSMG_00819	2.794e-68	239.0	COG3832@1|root,COG3832@2|Bacteria,2IMFE@201174|Actinobacteria	201174|Actinobacteria	S	Activator of Hsp90 ATPase homolog 1-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_7467781_2	298653.Franean1_2913	4.485e-28	113.0	COG2124@1|root,COG2124@2|Bacteria,2GJ3T@201174|Actinobacteria	298653.Franean1_2913|-	Q	cytochrome P450	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7467781_0	1172181.KB911714_gene4691	1.127e-82	295.0	COG1804@1|root,COG1804@2|Bacteria,2I8FK@201174|Actinobacteria	201174|Actinobacteria	C	CoA-transferase family III	-	-	-	-	-	-	-	-	-	-	-	-	CoA_transf_3
BYD2_k127_7467781_1	1123321.KB905816_gene2687	9.484e-66	252.0	COG1024@1|root,COG1024@2|Bacteria,2HSJH@201174|Actinobacteria	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_7467781_3	456442.Mboo_1020	0.0009318	47.0	COG0842@1|root,arCOG01467@2157|Archaea,2XU41@28890|Euryarchaeota,2N9R3@224756|Methanomicrobia	224756|Methanomicrobia	V	TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_7478109_5	1089544.KB912942_gene1809	4.285e-70	245.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria,4E07D@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_7478109_6	1089544.KB912942_gene1812	2.121e-66	241.0	COG1477@1|root,COG1477@2|Bacteria,2H74Y@201174|Actinobacteria,4DYZM@85010|Pseudonocardiales	201174|Actinobacteria	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	-	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
BYD2_k127_7478109_7	1089544.KB912942_gene1813	1.876e-53	197.0	COG1018@1|root,COG4097@1|root,COG1018@2|Bacteria,COG4097@2|Bacteria,2GKGS@201174|Actinobacteria	2|Bacteria	C	Oxidoreductase FAD-binding domain	paaE	GO:0000166,GO:0003674,GO:0005488,GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0036094,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051536,GO:0051537,GO:0051540,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0097159,GO:0098754,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575	1.18.1.3	ko:K00529,ko:K02613	ko00071,ko00360,ko01120,ko01220,map00071,map00360,map01120,map01220	M00545	R02000,R06782,R06783,R09838	RC00098,RC02690	br01602,ko00000,ko00001,ko00002,ko01000	-	-	iEcHS_1320.EcHS_A1479	FAD_binding_6,Fer2,NAD_binding_1
BYD2_k127_7478109_1	1313172.YM304_25790	5.796e-203	644.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4CP51@84992|Acidimicrobiia	201174|Actinobacteria	IQ	Protein synonym acyl-CoA synthetase	-	-	6.2.1.7	ko:K15868	ko00121,map00121	-	-	-	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_7478109_2	1211815.CBYP010000067_gene115	3.563e-182	581.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,4ETRJ@85013|Frankiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE1_1	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7478109_4	1394178.AWOO02000006_gene3301	1.82e-122	409.0	COG0076@1|root,COG0076@2|Bacteria,2GK3J@201174|Actinobacteria,4EIET@85012|Streptosporangiales	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.105,4.1.1.28,4.1.1.86	ko:K01593,ko:K13745	ko00260,ko00350,ko00360,ko00380,ko00901,ko00950,ko00965,ko01100,ko01110,ko01120,ko04726,ko04728,ko05030,ko05031,ko05034,map00260,map00350,map00360,map00380,map00901,map00950,map00965,map01100,map01110,map01120,map04726,map04728,map05030,map05031,map05034	M00037,M00042	R00685,R00699,R00736,R02080,R02701,R04909,R07650	RC00299	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Pyridoxal_deC
BYD2_k127_7478109_0	1123322.KB904691_gene4384	0.0	1089.0	COG4581@1|root,COG4581@2|Bacteria,2GJSV@201174|Actinobacteria	201174|Actinobacteria	L	dead DEAH box helicase	-	-	-	-	-	-	-	-	-	-	-	-	DEAD,DUF3516,Helicase_C
BYD2_k127_7478109_3	2002.JOEQ01000040_gene6070	1.332e-122	411.0	COG2272@1|root,COG2272@2|Bacteria,2GJCN@201174|Actinobacteria,4EFPV@85012|Streptosporangiales	201174|Actinobacteria	I	Belongs to the type-B carboxylesterase lipase family	-	-	-	ko:K03929	-	-	-	-	ko00000,ko01000	-	CE10	-	COesterase
BYD2_k127_7481836_0	1313172.YM304_41880	3.312e-224	723.0	COG2409@1|root,COG2409@2|Bacteria,2GJ5A@201174|Actinobacteria,4CNHT@84992|Acidimicrobiia	84992|Acidimicrobiia	S	MMPL family	-	-	-	ko:K06994	-	-	-	-	ko00000	-	-	-	MMPL
BYD2_k127_7481836_3	479432.Sros_0610	3.363e-120	400.0	COG4585@1|root,COG4585@2|Bacteria,2GS7K@201174|Actinobacteria,4EHT8@85012|Streptosporangiales	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
BYD2_k127_7481836_4	1380354.JIAN01000007_gene342	4.197e-107	355.0	COG2197@1|root,COG2197@2|Bacteria,2GMUG@201174|Actinobacteria	201174|Actinobacteria	T	Two component transcriptional regulator, LuxR family	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_7481836_1	1068980.ARVW01000001_gene1060	1.962e-170	542.0	COG0667@1|root,COG0667@2|Bacteria,2GMT5@201174|Actinobacteria,4DZWM@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
BYD2_k127_7481836_5	101510.RHA1_ro00627	2.135e-30	124.0	COG3631@1|root,COG3631@2|Bacteria	2|Bacteria	S	light absorption	-	-	-	-	-	-	-	-	-	-	-	-	DUF4440,SnoaL_2
BYD2_k127_7481836_2	37919.EP51_00055	2.835e-134	434.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4FWZP@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BYD2_k127_7481836_7	710687.KI912270_gene1273	2.292e-13	83.0	COG3801@1|root,COG3801@2|Bacteria,2IHXB@201174|Actinobacteria,23A1C@1762|Mycobacteriaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_7494647_1	40571.JOEA01000004_gene6331	1.183e-159	512.0	COG1960@1|root,COG1960@2|Bacteria,2HJFH@201174|Actinobacteria,4E0MB@85010|Pseudonocardiales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_2,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7494647_0	471852.Tcur_3582	8.685e-291	915.0	COG0058@1|root,COG0058@2|Bacteria,2GIVZ@201174|Actinobacteria,4EFHB@85012|Streptosporangiales	201174|Actinobacteria	G	Protein of unknown function (DUF3417)	glgP	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	DUF3417,Phosphorylase
BYD2_k127_7494647_5	1313172.YM304_10790	1.792e-102	339.0	COG1024@1|root,COG1024@2|Bacteria,2GJW5@201174|Actinobacteria,4CMYM@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_7494647_4	1313172.YM304_10780	3.919e-104	351.0	COG1703@1|root,COG1703@2|Bacteria,2GME8@201174|Actinobacteria,4CMYQ@84992|Acidimicrobiia	84992|Acidimicrobiia	E	ArgK protein	-	-	-	ko:K07588	-	-	-	-	ko00000,ko01000	-	-	-	ArgK
BYD2_k127_7494647_15	1313172.YM304_10770	4.721e-23	101.0	COG0694@1|root,COG0694@2|Bacteria,2HGE4@201174|Actinobacteria,4CNCF@84992|Acidimicrobiia	84992|Acidimicrobiia	O	NifU-like domain	-	-	-	-	-	-	-	-	-	-	-	-	NifU
BYD2_k127_7494647_6	1229780.BN381_10060	5.984e-85	306.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	-	-	-	ko:K08369	-	-	-	-	ko00000,ko02000	2.A.1	-	-	MFS_1,Sugar_tr
BYD2_k127_7494647_11	1304865.JAGF01000001_gene970	9.937e-29	125.0	COG1376@1|root,COG1376@2|Bacteria,2INDP@201174|Actinobacteria	201174|Actinobacteria	S	ErfK YbiS YcfS YnhG family protein	-	-	-	-	-	-	-	-	-	-	-	-	YkuD
BYD2_k127_7494647_7	446471.Xcel_0359	7.351e-65	235.0	COG3571@1|root,COG3571@2|Bacteria,2GKKE@201174|Actinobacteria,4F4CP@85017|Promicromonosporaceae	201174|Actinobacteria	S	Hydrolase of the alpha beta-hydrolase	-	-	-	ko:K07020	-	-	-	-	ko00000	-	-	-	DLH
BYD2_k127_7494647_10	1313172.YM304_10740	1.223e-56	205.0	COG2214@1|root,COG2214@2|Bacteria,2H5PV@201174|Actinobacteria	201174|Actinobacteria	O	DnaJ molecular chaperone homology domain	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7494647_12	1313172.YM304_10730	8.651e-28	123.0	294NP@1|root,2ZS20@2|Bacteria,2H9SR@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7494647_2	1229780.BN381_10054	2.909e-144	465.0	COG1494@1|root,COG1494@2|Bacteria,2GMQU@201174|Actinobacteria,3UW6A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	G	Bacterial fructose-1,6-bisphosphatase, glpX-encoded	glpX	GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576	3.1.3.11	ko:K02446	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_glpX
BYD2_k127_7494647_9	28042.GU90_08790	3.799e-61	220.0	COG0300@1|root,COG0300@2|Bacteria,2GKJE@201174|Actinobacteria,4E0RD@85010|Pseudonocardiales	201174|Actinobacteria	S	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
BYD2_k127_7494647_13	471856.Jden_0816	1.043e-25	113.0	COG1514@1|root,COG1514@2|Bacteria,2GRF0@201174|Actinobacteria	201174|Actinobacteria	J	2'-5' RNA ligase	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
BYD2_k127_7494647_8	1246474.ANBE01000026_gene1876	9.539e-62	228.0	COG1073@1|root,COG1073@2|Bacteria,2GJE5@201174|Actinobacteria,4EMGF@85012|Streptosporangiales	201174|Actinobacteria	S	Secretory lipase	-	-	-	-	-	-	-	-	-	-	-	-	LIP
BYD2_k127_7494647_16	1313172.YM304_10670	1.543e-22	110.0	COG0355@1|root,COG0355@2|Bacteria	2|Bacteria	C	proton-transporting ATP synthase activity, rotational mechanism	atpC	GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iLJ478.TM1609	ATP-synt_DE,ATP-synt_DE_N
BYD2_k127_7494647_3	1229780.BN381_10049	2.557e-121	392.0	COG0055@1|root,COG0055@2|Bacteria,2GIY6@201174|Actinobacteria,3UW86@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
BYD2_k127_7494705_1	525368.HMPREF0591_5826	6.727e-06	48.0	COG3832@1|root,COG3832@2|Bacteria,2IHQ1@201174|Actinobacteria,238XQ@1762|Mycobacteriaceae	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_7494705_2	1229172.JQFA01000002_gene3984	0.0007585	46.0	2F24Z@1|root,33V3F@2|Bacteria,1GDKB@1117|Cyanobacteria,1HFD7@1150|Oscillatoriales	1117|Cyanobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7494705_0	1380390.JIAT01000011_gene2492	8.746e-83	280.0	COG0262@1|root,COG0262@2|Bacteria,2GJU5@201174|Actinobacteria	201174|Actinobacteria	H	Bifunctional deaminase-reductase	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_74973_0	889378.Spiaf_2572	1.115e-89	320.0	COG1653@1|root,COG1653@2|Bacteria,2J6W1@203691|Spirochaetes	203691|Spirochaetes	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1
BYD2_k127_74973_1	471852.Tcur_2324	9.087e-75	256.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4EMXE@85012|Streptosporangiales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE_2
BYD2_k127_7500058_1	298653.Franean1_5615	5.807e-120	413.0	COG1028@1|root,COG2070@1|root,COG3321@1|root,COG1028@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,2H477@201174|Actinobacteria,4EU82@85013|Frankiales	201174|Actinobacteria	Q	Beta-ketoacyl synthase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,NMO,PP-binding,PS-DH,ketoacyl-synt
BYD2_k127_7500058_0	1449347.JQLN01000007_gene967	0.0	1240.0	COG3321@1|root,COG3321@2|Bacteria,2I38T@201174|Actinobacteria	201174|Actinobacteria	IQ	Acyl transferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_1,KAsynt_C_assoc,KR,Ketoacyl-synt_C,PP-binding,PS-DH,ketoacyl-synt
BYD2_k127_7500058_4	1229780.BN381_250018	2.352e-22	100.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
BYD2_k127_7500058_3	1229780.BN381_250020	4.821e-77	269.0	COG2267@1|root,COG2267@2|Bacteria,2I7V7@201174|Actinobacteria,3UWYE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1
BYD2_k127_7500058_2	287986.DV20_36525	3.136e-99	338.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4DYX8@85010|Pseudonocardiales	201174|Actinobacteria	CG	Glycosyltransferase family 28 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_28,UDPGT
BYD2_k127_7513900_9	1458357.BG58_31105	7.241e-15	79.0	COG1669@1|root,COG1669@2|Bacteria,1N17I@1224|Proteobacteria,2VVYD@28216|Betaproteobacteria,1KADC@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Nucleotidyltransferase domain	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
BYD2_k127_7513900_10	56110.Oscil6304_1850	3.379e-11	71.0	COG2361@1|root,COG2361@2|Bacteria,1G7TP@1117|Cyanobacteria,1HCDT@1150|Oscillatoriales	1117|Cyanobacteria	S	Protein of unknown function DUF86	-	-	-	-	-	-	-	-	-	-	-	-	DUF86
BYD2_k127_7513900_4	1313172.YM304_21030	4.844e-79	286.0	COG1466@1|root,COG1466@2|Bacteria,2HGGN@201174|Actinobacteria,4CNDU@84992|Acidimicrobiia	84992|Acidimicrobiia	L	dna polymerase III delta subunit	-	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	-
BYD2_k127_7513900_8	1229780.BN381_80262	5.415e-18	87.0	COG0268@1|root,COG0268@2|Bacteria,2IQ73@201174|Actinobacteria,3UWXJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Binds directly to 16S ribosomal RNA	rpsT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0040007,GO:0044424,GO:0044444,GO:0044464	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
BYD2_k127_7513900_0	525909.Afer_1296	4.41e-292	907.0	COG0481@1|root,COG0481@2|Bacteria,2GJAB@201174|Actinobacteria,4CMUT@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
BYD2_k127_7513900_3	1313172.YM304_21110	4.628e-92	314.0	COG1420@1|root,COG1420@2|Bacteria,2GKF5@201174|Actinobacteria,4CN2R@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA
BYD2_k127_7513900_2	1313172.YM304_21120	9.45e-125	411.0	COG0484@1|root,COG0484@2|Bacteria,2GK69@201174|Actinobacteria,4CMQ3@84992|Acidimicrobiia	84992|Acidimicrobiia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
BYD2_k127_7513900_6	1229780.BN381_80273	2.275e-33	148.0	COG1385@1|root,COG1385@2|Bacteria,2GTKX@201174|Actinobacteria,3UWZU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	-	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
BYD2_k127_7513900_5	1229780.BN381_80274	1.473e-46	174.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BYD2_k127_7513900_1	1313172.YM304_21150	1.041e-136	452.0	COG0635@1|root,COG0635@2|Bacteria,2GJXX@201174|Actinobacteria,4CNTM@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
BYD2_k127_7513900_7	1283283.ATXA01000003_gene1715	2.825e-23	104.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,2GNP7@201174|Actinobacteria,4EUZW@85013|Frankiales	201174|Actinobacteria	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD3	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	ACCA,Carboxyl_trans,MdcE
BYD2_k127_7531591_0	525909.Afer_0529	2.597e-174	559.0	COG0143@1|root,COG0143@2|Bacteria,2GK4S@201174|Actinobacteria,4CMP6@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1g
BYD2_k127_7531591_1	1463856.JOHY01000001_gene478	2.715e-74	283.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
BYD2_k127_7531591_2	1206737.BAGF01000027_gene1614	3.135e-38	148.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria,4G2PZ@85025|Nocardiaceae	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
BYD2_k127_7544063_0	1313172.YM304_20720	2.593e-181	587.0	COG0072@1|root,COG0073@1|root,COG0072@2|Bacteria,COG0073@2|Bacteria,2GMFD@201174|Actinobacteria,4CMUN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	B3/4 domain	pheT	-	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA_bind
BYD2_k127_7544063_1	935567.JAES01000001_gene2242	1.314e-93	327.0	COG0016@1|root,COG0016@2|Bacteria,1MVD7@1224|Proteobacteria,1RN22@1236|Gammaproteobacteria,1X40X@135614|Xanthomonadales	135614|Xanthomonadales	J	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily	pheS	GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
BYD2_k127_7544063_2	479432.Sros_6084	4.278e-41	162.0	COG0566@1|root,COG0566@2|Bacteria,2GJI6@201174|Actinobacteria,4EH5S@85012|Streptosporangiales	201174|Actinobacteria	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	tsnR	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
BYD2_k127_7548039_0	326424.FRAAL0380	4.942e-209	660.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,4ERKB@85013|Frankiales	201174|Actinobacteria	E	Belongs to the group II decarboxylase family	gadB	-	4.1.1.15	ko:K01580	ko00250,ko00410,ko00430,ko00650,ko01100,ko01110,ko01120,ko02024,ko04727,ko04940,map00250,map00410,map00430,map00650,map01100,map01110,map01120,map02024,map04727,map04940	M00027	R00261,R00489,R01682,R02466	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
BYD2_k127_7548039_2	882083.SacmaDRAFT_0793	9.891e-116	381.0	COG2378@1|root,COG2378@2|Bacteria,2GIZC@201174|Actinobacteria,4E1PX@85010|Pseudonocardiales	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
BYD2_k127_7548039_1	426716.JOAJ01000005_gene2476	1.279e-186	605.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4FUCF@85025|Nocardiaceae	201174|Actinobacteria	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	ko:K21159	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	EHN
BYD2_k127_7548039_4	1214101.BN159_1433	2.032e-42	162.0	COG3245@1|root,COG3245@2|Bacteria,2IGG3@201174|Actinobacteria	201174|Actinobacteria	C	cytochrome	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7548039_5	1906.SFRA_06155	1.936e-33	139.0	COG1846@1|root,COG1846@2|Bacteria,2IPXE@201174|Actinobacteria	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
BYD2_k127_7548039_3	103733.JNYO01000033_gene7293	1.198e-79	284.0	COG2909@1|root,COG2909@2|Bacteria,2GJXF@201174|Actinobacteria,4DYUD@85010|Pseudonocardiales	201174|Actinobacteria	K	luxR family	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_7557555_1	1056816.JAFQ01000004_gene961	1.522e-10	72.0	2EQSP@1|root,33ICH@2|Bacteria,2GWX9@201174|Actinobacteria,4G2K3@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7557555_0	500153.JOEK01000009_gene5050	5.659e-52	196.0	COG0500@1|root,COG2226@2|Bacteria,2GM0Y@201174|Actinobacteria	201174|Actinobacteria	Q	Methyltransferase type 11	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
BYD2_k127_7582256_3	675635.Psed_2926	4.359e-71	245.0	COG2030@1|root,COG2030@2|Bacteria,2GJJI@201174|Actinobacteria,4DZ02@85010|Pseudonocardiales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	htdY	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N,MaoC_dehydratas
BYD2_k127_7582256_1	1229780.BN381_250119	3.007e-125	430.0	COG1028@1|root,COG1028@2|Bacteria,2GJ1F@201174|Actinobacteria,3UX8U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	IQ	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_7582256_2	1229780.BN381_10280	6.434e-78	288.0	COG2720@1|root,COG2720@2|Bacteria,2GISH@201174|Actinobacteria,3UXFH@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	V	VanW like protein	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,VanW
BYD2_k127_7582256_0	1229780.BN381_10278	5.468e-136	444.0	COG0644@1|root,COG0644@2|Bacteria,2HG44@201174|Actinobacteria,3UXPV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_3
BYD2_k127_7604352_5	1313172.YM304_08910	8.899e-57	210.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,2GJHB@201174|Actinobacteria,4CMZ5@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	Carb_kinase,YjeF_N
BYD2_k127_7604352_6	953739.SVEN_7032	3.211e-31	126.0	COG0736@1|root,COG0736@2|Bacteria,2IPP4@201174|Actinobacteria	201174|Actinobacteria	I	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein	-	-	2.7.8.7	ko:K00997	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
BYD2_k127_7604352_0	1229780.BN381_130026	0.0	1242.0	COG0449@1|root,COG0449@2|Bacteria,2GKH0@201174|Actinobacteria,3UWEV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016020,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:0071944,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	iNJ661.Rv3436c	GATase_6,SIS
BYD2_k127_7604352_4	448385.sce6697	7.127e-63	239.0	COG1309@1|root,COG1309@2|Bacteria,1QE6M@1224|Proteobacteria,434KH@68525|delta/epsilon subdivisions,2X8XJ@28221|Deltaproteobacteria,2Z0VW@29|Myxococcales	28221|Deltaproteobacteria	K	Tetracyclin repressor, C-terminal all-alpha domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
BYD2_k127_7604352_1	58123.JOFJ01000014_gene5121	2.574e-113	376.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria,4EG8T@85012|Streptosporangiales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
BYD2_k127_7604352_3	469383.Cwoe_5654	1.142e-97	342.0	COG0842@1|root,COG0842@2|Bacteria,2GKJF@201174|Actinobacteria,4CRF3@84995|Rubrobacteria	84995|Rubrobacteria	V	ABC-2 type transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane
BYD2_k127_7604352_2	1313172.YM304_08820	1.337e-112	377.0	COG1109@1|root,COG1109@2|Bacteria,2GN87@201174|Actinobacteria,4CMWY@84992|Acidimicrobiia	84992|Acidimicrobiia	G	Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
BYD2_k127_764221_5	408672.NBCG_02905	4.52e-25	109.0	COG3682@1|root,COG3682@2|Bacteria,2IIIT@201174|Actinobacteria,4DSCQ@85009|Propionibacteriales	201174|Actinobacteria	K	Penicillinase repressor	blaI	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
BYD2_k127_764221_3	1206737.BAGF01000144_gene5735	1.279e-50	189.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
BYD2_k127_764221_6	1122182.KB903821_gene1273	1.147e-05	57.0	2B3DA@1|root,31W23@2|Bacteria,2INNH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_764221_2	1123504.JQKD01000003_gene667	4.922e-128	415.0	COG3588@1|root,COG3588@2|Bacteria,1MVFK@1224|Proteobacteria	1224|Proteobacteria	G	fructose-bisphosphate aldolase	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
BYD2_k127_764221_4	526225.Gobs_1056	4.259e-45	169.0	COG1018@1|root,COG1018@2|Bacteria,2HTUU@201174|Actinobacteria,4EUPB@85013|Frankiales	201174|Actinobacteria	C	PFAM Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
BYD2_k127_764221_0	1120950.KB892774_gene1247	1.312e-165	524.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DPI3@85009|Propionibacteriales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_764221_1	1380355.JNIJ01000037_gene5325	1.674e-152	489.0	COG0604@1|root,COG0604@2|Bacteria,1MXRA@1224|Proteobacteria,2U144@28211|Alphaproteobacteria,3JV4Z@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_7657164_6	314345.SPV1_13302	1.679e-47	174.0	COG0078@1|root,COG0078@2|Bacteria,1MUFM@1224|Proteobacteria	1224|Proteobacteria	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
BYD2_k127_7657164_5	1229780.BN381_290119	1.665e-52	198.0	COG1438@1|root,COG1438@2|Bacteria,2GKA5@201174|Actinobacteria,3UWW0@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Arginine repressor, DNA binding domain	argR	GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
BYD2_k127_7657164_1	1161401.ASJA01000022_gene121	4.271e-165	530.0	COG0137@1|root,COG0137@2|Bacteria,1MV0Y@1224|Proteobacteria,2TTGS@28211|Alphaproteobacteria,43WGQ@69657|Hyphomonadaceae	28211|Alphaproteobacteria	E	Belongs to the argininosuccinate synthase family. Type 1 subfamily	argG	GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
BYD2_k127_7657164_0	1313172.YM304_20840	4.748e-184	597.0	COG0165@1|root,COG0165@2|Bacteria,2GJ2A@201174|Actinobacteria,4CMW7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Argininosuccinate lyase C-terminal	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
BYD2_k127_7657164_3	666685.R2APBS1_2741	1.185e-75	263.0	COG2094@1|root,COG2094@2|Bacteria,1RE0A@1224|Proteobacteria,1S9CM@1236|Gammaproteobacteria,1X6BU@135614|Xanthomonadales	135614|Xanthomonadales	L	Belongs to the DNA glycosylase MPG family	-	GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.2.2.21	ko:K03652	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Pur_DNA_glyco
BYD2_k127_7657164_4	1123320.KB889684_gene2300	6.568e-73	255.0	COG1024@1|root,COG1024@2|Bacteria,2GJ7Z@201174|Actinobacteria	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	echA12	GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_7657164_2	383372.Rcas_1792	1.094e-124	414.0	COG0162@1|root,COG0162@2|Bacteria,2G64J@200795|Chloroflexi,375RR@32061|Chloroflexia	32061|Chloroflexia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
BYD2_k127_770319_0	1229780.BN381_250066	1.168e-124	408.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_770319_1	1313172.YM304_05060	1.67e-48	183.0	COG1413@1|root,COG1413@2|Bacteria,2HA0J@201174|Actinobacteria,4CNCY@84992|Acidimicrobiia	84992|Acidimicrobiia	C	PBS lyase HEAT-like repeat	-	-	-	-	-	-	-	-	-	-	-	-	HEAT_2
BYD2_k127_770319_2	471852.Tcur_0954	6.718e-14	83.0	COG1309@1|root,COG1309@2|Bacteria,2GJHJ@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_7734805_4	1234595.C725_2886	7.777e-38	150.0	COG1946@1|root,COG1946@2|Bacteria,1MV9R@1224|Proteobacteria,2TRFD@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	acyl-CoA thioesterase	tesB	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042802,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0047617,GO:0051186,GO:0055086,GO:0071704,GO:0072329,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901575	-	ko:K10805	ko01040,map01040	-	-	-	ko00000,ko00001,ko01000,ko01004	-	-	-	4HBT_3
BYD2_k127_7734805_1	66874.JOFS01000005_gene3953	5.16e-84	283.0	COG1309@1|root,COG1309@2|Bacteria,2IFKE@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_7734805_6	66874.JOFS01000005_gene3954	3.314e-27	121.0	2DMAG@1|root,32C8H@2|Bacteria,2IKM5@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2867
BYD2_k127_7734805_8	106370.Francci3_1195	0.0003638	46.0	COG1396@1|root,COG1396@2|Bacteria,2I3J1@201174|Actinobacteria	201174|Actinobacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7734805_3	40571.JOEA01000030_gene5596	5.483e-38	147.0	COG0454@1|root,COG0456@2|Bacteria,2IJC7@201174|Actinobacteria,4E5XB@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_7734805_5	1306174.JODP01000027_gene130	1.306e-32	129.0	2CFVG@1|root,3346Y@2|Bacteria,2GRCI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF1059
BYD2_k127_7734805_2	390989.JOEG01000021_gene2597	9.668e-53	192.0	COG0537@1|root,COG0537@2|Bacteria,2ISE6@201174|Actinobacteria	201174|Actinobacteria	FG	HIT domain	-	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
BYD2_k127_7734805_7	405948.SACE_0961	4.004e-23	104.0	COG1734@1|root,COG1734@2|Bacteria,2I16A@201174|Actinobacteria,4E6FX@85010|Pseudonocardiales	201174|Actinobacteria	T	Prokaryotic dksA/traR C4-type zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-dskA_traR
BYD2_k127_7734805_0	1313172.YM304_26020	7.18e-199	623.0	COG0638@1|root,COG0638@2|Bacteria,2GMC6@201174|Actinobacteria,4CMS0@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine	pafA	-	6.3.1.19	ko:K13571	-	M00342	R11207	RC00090,RC00096	ko00000,ko00002,ko01000,ko03051	-	-	-	Pup_ligase
BYD2_k127_7752239_9	1380390.JIAT01000016_gene5528	7.463e-05	45.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4CRUY@84995|Rubrobacteria	84995|Rubrobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7752239_7	710111.FraQA3DRAFT_6362	3.025e-31	132.0	COG1309@1|root,COG1309@2|Bacteria,2I9NV@201174|Actinobacteria,4EW00@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional repressor C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
BYD2_k127_7752239_0	1313172.YM304_32120	7.126e-149	500.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4CNFR@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_7752239_3	1229780.BN381_10079	1.926e-116	407.0	COG0482@1|root,COG0482@2|Bacteria,2GIUQ@201174|Actinobacteria,3UW6U@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
BYD2_k127_7752239_4	1313172.YM304_12550	1.454e-113	378.0	COG1104@1|root,COG1104@2|Bacteria,2GKUT@201174|Actinobacteria,4CN5Q@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class-V	-	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
BYD2_k127_7752239_6	1313172.YM304_12540	8.481e-40	159.0	COG1714@1|root,COG1714@2|Bacteria,2H4MP@201174|Actinobacteria	201174|Actinobacteria	A	PFAM RDD domain containing protein	-	-	-	-	-	-	-	-	-	-	-	-	RDD
BYD2_k127_7752239_5	1313172.YM304_12530	5.683e-91	310.0	COG1300@1|root,COG1300@2|Bacteria,2GJTG@201174|Actinobacteria	201174|Actinobacteria	S	membrane	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
BYD2_k127_7752239_1	1229780.BN381_10075	2.299e-130	432.0	COG1721@1|root,COG1721@2|Bacteria,2GK9A@201174|Actinobacteria,3UXC5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF58
BYD2_k127_7752239_2	1043205.AFYF01000056_gene2650	4.446e-129	422.0	COG0714@1|root,COG0714@2|Bacteria,2GK07@201174|Actinobacteria,4FEQS@85021|Intrasporangiaceae	201174|Actinobacteria	S	ATPase family associated with various cellular activities (AAA)	moxR2	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
BYD2_k127_7752239_8	465541.ATCJ01000005_gene3544	8.112e-29	129.0	29B69@1|root,2ZY4N@2|Bacteria,2GKQW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF4350
BYD2_k127_7771241_6	1089544.KB912942_gene1809	3.523e-65	232.0	COG0642@1|root,COG0642@2|Bacteria,2I2VJ@201174|Actinobacteria,4E07D@85010|Pseudonocardiales	201174|Actinobacteria	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_7771241_5	1089544.KB912942_gene1808	3.588e-86	294.0	COG0745@1|root,COG0745@2|Bacteria,2GKJK@201174|Actinobacteria,4DYT4@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	tcsR4	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_7771241_8	110319.CF8_4068	3.768e-51	198.0	COG1409@1|root,COG1409@2|Bacteria,2GP0C@201174|Actinobacteria,4DS7R@85009|Propionibacteriales	201174|Actinobacteria	S	Calcineurin-like phosphoesterase	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
BYD2_k127_7771241_9	58123.JOFJ01000005_gene1300	5.331e-22	111.0	COG0392@1|root,COG0671@1|root,COG3642@1|root,COG0392@2|Bacteria,COG0671@2|Bacteria,COG3642@2|Bacteria,2GMAV@201174|Actinobacteria,4EHD3@85012|Streptosporangiales	201174|Actinobacteria	I	Lysylphosphatidylglycerol synthase TM region	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	LPG_synthase_TM,PAP2
BYD2_k127_7771241_1	477641.MODMU_2304	4.4e-154	507.0	COG0671@1|root,COG1718@1|root,COG0671@2|Bacteria,COG1718@2|Bacteria	2|Bacteria	DT	cellular response to dsDNA	kdkA	-	2.7.1.166,3.6.1.27	ko:K11211,ko:K19302	ko00540,ko00550,map00540,map00550	-	R05627,R09767	RC00002,RC00078	ko00000,ko00001,ko01000,ko01011	-	-	-	Kdo,PAP2
BYD2_k127_7771241_7	477641.MODMU_2303	2.227e-58	220.0	COG1732@1|root,COG1732@2|Bacteria,2GJWY@201174|Actinobacteria,4EVAF@85013|Frankiales	201174|Actinobacteria	M	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	ko:K05845	ko02010,map02010	M00209	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.12	-	-	OpuAC
BYD2_k127_7771241_3	1449346.JQMO01000002_gene254	1.118e-106	364.0	COG1653@1|root,COG1653@2|Bacteria,2GJXB@201174|Actinobacteria,2M0QC@2063|Kitasatospora	201174|Actinobacteria	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10232	ko02010,map02010	M00201	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.32,3.A.1.1.8	-	-	SBP_bac_1,SBP_bac_8
BYD2_k127_7771241_4	1048339.KB913029_gene2529	2.941e-103	347.0	COG1136@1|root,COG1136@2|Bacteria,2GJN6@201174|Actinobacteria,4ES91@85013|Frankiales	201174|Actinobacteria	V	PFAM ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_7771241_0	1048339.KB913029_gene2528	1.448e-238	764.0	COG3127@1|root,COG3127@2|Bacteria,2H37M@201174|Actinobacteria,4ERZ6@85013|Frankiales	201174|Actinobacteria	Q	MacB-like periplasmic core domain	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
BYD2_k127_7771241_10	146922.JOFU01000009_gene946	4.468e-19	92.0	COG2905@1|root,COG2905@2|Bacteria,2IJJ6@201174|Actinobacteria	201174|Actinobacteria	T	Domain in cystathionine beta-synthase and other proteins.	-	-	-	-	-	-	-	-	-	-	-	-	CBS
BYD2_k127_7771241_15	326427.Cagg_3794	1.741e-07	62.0	COG0589@1|root,COG0589@2|Bacteria,2G8FB@200795|Chloroflexi,377FW@32061|Chloroflexia	32061|Chloroflexia	T	Belongs to the universal stress protein A family	-	-	-	-	-	-	-	-	-	-	-	-	Usp
BYD2_k127_7771241_11	926690.KE386573_gene1979	4.616e-19	101.0	COG0589@1|root,arCOG00449@2157|Archaea,2XU1P@28890|Euryarchaeota,23SZU@183963|Halobacteria	183963|Halobacteria	T	COG0589 Universal stress protein UspA and related nucleotide-binding proteins	-	-	-	-	-	-	-	-	-	-	-	-	Fer2,Usp
BYD2_k127_7771241_13	68170.KL590477_gene2565	2.512e-11	76.0	2BNZV@1|root,32HQ2@2|Bacteria,2H5IX@201174|Actinobacteria,4EB3P@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_7771241_14	1101188.KI912155_gene2607	5.589e-11	75.0	COG0236@1|root,COG0236@2|Bacteria,2GRZ8@201174|Actinobacteria	201174|Actinobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
BYD2_k127_7771241_2	290399.Arth_0508	8.355e-125	412.0	COG0508@1|root,COG0508@2|Bacteria,2GN5J@201174|Actinobacteria	201174|Actinobacteria	C	acetyltransferase component of pyruvate dehydrogenase complex	-	-	2.3.1.12,2.3.1.61	ko:K00627,ko:K00658	ko00010,ko00020,ko00310,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00310,map00620,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00032,M00307	R00209,R02569,R02570,R02571,R08549	RC00004,RC02727,RC02742,RC02833,RC02857	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	2-oxoacid_dh,Biotin_lipoyl,E3_binding
BYD2_k127_7774057_3	285535.JOEY01000006_gene8113	1.266e-210	660.0	COG1228@1|root,COG1228@2|Bacteria,2GMUS@201174|Actinobacteria	201174|Actinobacteria	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
BYD2_k127_7774057_15	1120960.ATXG01000001_gene1176	4.661e-55	196.0	COG0454@1|root,COG0456@2|Bacteria,2I3PH@201174|Actinobacteria	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_7774057_10	285535.JOEY01000006_gene8112	2.836e-118	398.0	COG1028@1|root,COG1028@2|Bacteria,2GJU1@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
BYD2_k127_7774057_11	298655.KI912266_gene2267	2.588e-97	338.0	COG2141@1|root,COG2141@2|Bacteria,2GU1D@201174|Actinobacteria	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_7774057_13	285535.JOEY01000006_gene8123	2.683e-68	257.0	COG1309@1|root,COG1309@2|Bacteria,2IAMN@201174|Actinobacteria	201174|Actinobacteria	K	PFAM regulatory protein TetR	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_7774057_0	246196.MSMEI_4702	2.021e-234	741.0	COG1960@1|root,COG1960@2|Bacteria,2GKQI@201174|Actinobacteria,232CR@1762|Mycobacteriaceae	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7774057_7	285535.JOEY01000006_gene8125	4.68e-179	579.0	COG3173@1|root,COG3173@2|Bacteria,2GJ58@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_7774057_18	1206726.BAFV01000122_gene6173	1.511e-34	150.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4FY8V@85025|Nocardiaceae	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_7774057_19	285535.JOEY01000056_gene6723	1.808e-32	136.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_7774057_16	298653.Franean1_0095	2.643e-53	192.0	COG0604@1|root,COG0604@2|Bacteria,2GMHR@201174|Actinobacteria,4ESNW@85013|Frankiales	201174|Actinobacteria	C	PFAM Alcohol dehydrogenase zinc-binding domain protein	-	-	1.6.5.5	ko:K00344	-	-	-	-	ko00000,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_7774057_20	285535.JOEY01000009_gene6665	1.563e-14	77.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_7774057_4	285535.JOEY01000009_gene6665	1.805e-200	631.0	COG2159@1|root,COG2159@2|Bacteria,2GKG2@201174|Actinobacteria	201174|Actinobacteria	S	Pfam Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_7774057_2	875328.JDM601_2345	4.899e-225	725.0	COG2141@1|root,COG2141@2|Bacteria,2GJAN@201174|Actinobacteria,232GT@1762|Mycobacteriaceae	201174|Actinobacteria	C	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_7774057_6	931627.MycrhDRAFT_1061	8.932e-185	591.0	COG1804@1|root,COG1804@2|Bacteria,2GIU7@201174|Actinobacteria,23534@1762|Mycobacteriaceae	201174|Actinobacteria	C	PFAM L-carnitine dehydratase bile acid-inducible protein F	-	-	2.8.3.16	ko:K07749	-	-	-	-	ko00000,ko01000	-	-	-	CoA_transf_3
BYD2_k127_7774057_8	298653.Franean1_6909	3.616e-149	497.0	COG2301@1|root,COG2301@2|Bacteria,2GK5J@201174|Actinobacteria,4ESAE@85013|Frankiales	201174|Actinobacteria	G	Belongs to the HpcH HpaI aldolase family	-	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
BYD2_k127_7774057_9	365528.KB891231_gene193	9.29e-134	430.0	COG1024@1|root,COG1024@2|Bacteria,2GNZE@201174|Actinobacteria,4EUFA@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_7774057_21	1160137.KB907307_gene2803	2.2e-10	73.0	COG3804@1|root,COG3804@2|Bacteria,2GKE3@201174|Actinobacteria,4FU6W@85025|Nocardiaceae	201174|Actinobacteria	S	dihydrodipicolinate reductase	-	-	1.4.1.12,1.4.1.26	ko:K21672	ko00310,ko00330,ko00472,map00310,map00330,map00472	-	R02825,R04200,R04201,R04687,R04688	RC00249,RC00790	ko00000,ko00001,ko01000	-	-	-	DapB_N
BYD2_k127_7774057_5	222534.KB893724_gene440	1.93e-185	592.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria,4EUFP@85013|Frankiales	201174|Actinobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
BYD2_k127_7774057_17	285535.JOEY01000006_gene8114	1.662e-42	159.0	2EUA2@1|root,33MSG@2|Bacteria,2IMWS@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7774057_1	285535.JOEY01000006_gene8115	1.495e-229	719.0	COG4638@1|root,COG4638@2|Bacteria,2GKJY@201174|Actinobacteria	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	-	-	-	-	-	-	-	-	-	Rieske,Ring_hydroxyl_A
BYD2_k127_7774057_14	710685.MycrhN_5823	8.386e-68	235.0	COG2128@1|root,COG2128@2|Bacteria,2IKC6@201174|Actinobacteria,239UT@1762|Mycobacteriaceae	201174|Actinobacteria	S	Carboxymuconolactone decarboxylase family	-	-	-	-	-	-	-	-	-	-	-	-	CMD
BYD2_k127_7774057_12	1123322.KB904634_gene2232	1.359e-79	270.0	COG0262@1|root,COG0262@2|Bacteria,2GJJD@201174|Actinobacteria	201174|Actinobacteria	H	bifunctional deaminase-reductase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_7774685_10	573370.DMR_30730	1.057e-35	149.0	COG0500@1|root,COG2226@2|Bacteria,1N3VV@1224|Proteobacteria,42TZE@68525|delta/epsilon subdivisions,2WQ3D@28221|Deltaproteobacteria	28221|Deltaproteobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_31
BYD2_k127_7774685_3	222534.KB893728_gene5567	1.039e-57	210.0	COG0346@1|root,COG0346@2|Bacteria,2IPA6@201174|Actinobacteria,4EW05@85013|Frankiales	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_7774685_1	196162.Noca_1617	2.591e-77	270.0	COG0053@1|root,COG0053@2|Bacteria	2|Bacteria	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	2.5.1.105	ko:K04088,ko:K06897	ko00790,map00790	M00742	R10339	RC00121	ko00000,ko00001,ko00002,ko01000	-	-	-	Cation_efflux,ZT_dimer
BYD2_k127_7774685_4	710421.Mycch_2074	1.189e-56	206.0	arCOG11509@1|root,31KIR@2|Bacteria,2IGM0@201174|Actinobacteria,23A9A@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7774685_13	196162.Noca_1618	1.389e-24	106.0	COG3224@1|root,COG3224@2|Bacteria	2|Bacteria	-	-	-	-	-	ko:K09932	-	-	-	-	ko00000	-	-	-	ABM
BYD2_k127_7774685_5	1120949.KB903294_gene4508	2.229e-52	194.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,4DMQI@85008|Micromonosporales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	ko:K21209	ko01059,map01059	-	-	-	ko00000,ko00001	-	-	-	Abhydrolase_6
BYD2_k127_7774685_8	1214101.BN159_3836	5.067e-39	154.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
BYD2_k127_7774685_11	1292020.H483_0117340	3.263e-30	129.0	COG3547@1|root,COG3547@2|Bacteria,2GS79@201174|Actinobacteria	201174|Actinobacteria	L	Transposase IS116 IS110 IS902	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
BYD2_k127_7774685_14	1340493.JNIF01000004_gene311	1.87e-20	97.0	COG1680@1|root,COG1680@2|Bacteria,3Y7U9@57723|Acidobacteria	57723|Acidobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
BYD2_k127_7774685_16	1235457.C404_02835	3.334e-06	59.0	COG1680@1|root,COG1680@2|Bacteria,1RIYG@1224|Proteobacteria	1224|Proteobacteria	V	Beta-lactamase	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF4440
BYD2_k127_7774685_7	479432.Sros_5212	1.896e-40	158.0	COG2227@1|root,COG2227@2|Bacteria,2H5TR@201174|Actinobacteria,4EK1M@85012|Streptosporangiales	201174|Actinobacteria	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25
BYD2_k127_7774685_6	1246995.AFR_10835	2.578e-42	167.0	COG2940@1|root,COG2940@2|Bacteria,2GQAV@201174|Actinobacteria	201174|Actinobacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
BYD2_k127_7774685_9	68570.DC74_8157	1.691e-36	144.0	COG1708@1|root,COG1708@2|Bacteria,2IT8Y@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
BYD2_k127_7774685_2	219305.MCAG_05351	2.686e-72	253.0	COG0406@1|root,COG0406@2|Bacteria,2IJ7S@201174|Actinobacteria,4DDQU@85008|Micromonosporales	201174|Actinobacteria	G	Histidine phosphatase superfamily (branch 1)	-	-	5.4.2.12	ko:K15634	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
BYD2_k127_7774685_12	644283.Micau_0123	3.546e-28	116.0	COG0262@1|root,COG0262@2|Bacteria,2GYU7@201174|Actinobacteria,4DM4I@85008|Micromonosporales	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_7774685_0	1120936.KB907208_gene1207	1.936e-80	282.0	COG3794@1|root,COG3794@2|Bacteria,2IR44@201174|Actinobacteria	201174|Actinobacteria	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7774685_15	644966.Tmar_1545	1.005e-14	82.0	COG1309@1|root,COG1309@2|Bacteria,1UW2U@1239|Firmicutes,25MK5@186801|Clostridia,3WDJS@538999|Clostridiales incertae sedis	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_7774685_17	1136417.AZWE01000024_gene697	0.0001368	47.0	COG2801@1|root,COG2801@2|Bacteria,2GJ3V@201174|Actinobacteria,4DEFF@85008|Micromonosporales	201174|Actinobacteria	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_32,LZ_Tnp_IS481,rve,rve_3
BYD2_k127_7778064_3	471852.Tcur_0104	3.016e-98	325.0	COG0388@1|root,COG0388@2|Bacteria,2IFF1@201174|Actinobacteria,4EQ4G@85012|Streptosporangiales	201174|Actinobacteria	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
BYD2_k127_7778064_1	1122611.KB903940_gene1759	4.797e-183	593.0	COG1640@1|root,COG1640@2|Bacteria,2GM5Z@201174|Actinobacteria,4EGEU@85012|Streptosporangiales	201174|Actinobacteria	G	4-alpha-glucanotransferase	-	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
BYD2_k127_7778064_7	1313172.YM304_21360	3.218e-17	84.0	29B43@1|root,2ZY2Q@2|Bacteria,2HD3P@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7778064_6	1313172.YM304_21370	2.894e-66	257.0	COG3707@1|root,COG3707@2|Bacteria,2GK7T@201174|Actinobacteria,4CN3I@84992|Acidimicrobiia	84992|Acidimicrobiia	T	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR,Response_reg
BYD2_k127_7778064_0	1229780.BN381_80407	0.0	1108.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,2GJY2@201174|Actinobacteria,3UWEE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0030312,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
BYD2_k127_7778064_5	543632.JOJL01000008_gene5619	2.682e-66	234.0	COG0702@1|root,COG0702@2|Bacteria,2GKNN@201174|Actinobacteria,4DETW@85008|Micromonosporales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
BYD2_k127_7778064_4	1229780.BN381_100036	5.463e-82	286.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	-	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Methyltransf_25,Methyltransf_31
BYD2_k127_7778064_2	1313172.YM304_21410	8.427e-142	483.0	COG0539@1|root,COG0539@2|Bacteria,2GJAK@201174|Actinobacteria,4CMW4@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein S1-like RNA-binding domain	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
BYD2_k127_7781392_8	1313172.YM304_08350	1.329e-64	222.0	COG0093@1|root,COG0093@2|Bacteria,2IHNX@201174|Actinobacteria,4CMZN@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
BYD2_k127_7781392_12	742818.HMPREF9451_00230	5.248e-32	133.0	COG0198@1|root,COG0198@2|Bacteria,2IKP2@201174|Actinobacteria,4CWBG@84998|Coriobacteriia	84998|Coriobacteriia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
BYD2_k127_7781392_3	525909.Afer_0410	1.387e-83	280.0	COG0094@1|root,COG0094@2|Bacteria,2GJW7@201174|Actinobacteria,4CMX7@84992|Acidimicrobiia	84992|Acidimicrobiia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
BYD2_k127_7781392_13	1078020.KEK_12083	4.263e-28	113.0	COG0199@1|root,COG0199@2|Bacteria,2IQ8R@201174|Actinobacteria,23AM9@1762|Mycobacteriaceae	201174|Actinobacteria	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
BYD2_k127_7781392_10	1229780.BN381_450083	9.096e-53	196.0	COG0096@1|root,COG0096@2|Bacteria,2IHQZ@201174|Actinobacteria,3UWN2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
BYD2_k127_7781392_7	1203605.HMPREF1531_00167	2.681e-68	239.0	COG0097@1|root,COG0097@2|Bacteria,2GK35@201174|Actinobacteria,4DNFZ@85009|Propionibacteriales	201174|Actinobacteria	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
BYD2_k127_7781392_11	1519439.JPJG01000018_gene260	4.443e-33	131.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,2N7DA@216572|Oscillospiraceae	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
BYD2_k127_7781392_5	1229780.BN381_450080	1.667e-77	273.0	COG0098@1|root,COG0098@2|Bacteria,2GJW8@201174|Actinobacteria,3UWH1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
BYD2_k127_7781392_14	1313172.YM304_08430	3.365e-20	100.0	COG1841@1|root,COG1841@2|Bacteria,2HGDQ@201174|Actinobacteria,4CNC3@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
BYD2_k127_7781392_9	1229780.BN381_450078	6.469e-63	227.0	COG0200@1|root,COG0200@2|Bacteria,2II6M@201174|Actinobacteria,3UWM5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	binds to the 23S rRNA	rplO	GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
BYD2_k127_7781392_1	1313172.YM304_08450	7.736e-154	497.0	COG0201@1|root,COG0201@2|Bacteria,2GJ26@201174|Actinobacteria,4CMWZ@84992|Acidimicrobiia	84992|Acidimicrobiia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
BYD2_k127_7781392_6	1313172.YM304_08460	2.778e-70	260.0	COG0563@1|root,COG0563@2|Bacteria,2GJ7T@201174|Actinobacteria,4CMZ1@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ADK,ADK_lid
BYD2_k127_7781392_4	479434.Sthe_1058	1.199e-81	278.0	COG0024@1|root,COG0024@2|Bacteria,2G6AV@200795|Chloroflexi,27XSR@189775|Thermomicrobia	200795|Chloroflexi	J	Methionine aminopeptidase	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
BYD2_k127_7781392_2	44060.JODL01000005_gene548	3.34e-93	310.0	COG0262@1|root,COG0262@2|Bacteria,2IF6H@201174|Actinobacteria	201174|Actinobacteria	H	RibD C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	RibD_C
BYD2_k127_7781392_0	1394178.AWOO02000017_gene6680	3.811e-181	588.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EHSW@85012|Streptosporangiales	201174|Actinobacteria	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,TPR_12,Trans_reg_C
BYD2_k127_7784190_14	266117.Rxyl_2529	3.864e-37	148.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
BYD2_k127_7784190_4	1299327.I546_5694	3.234e-139	453.0	COG1752@1|root,COG1752@2|Bacteria,2GNBM@201174|Actinobacteria,234XD@1762|Mycobacteriaceae	201174|Actinobacteria	S	Contains patatin domain. This family consists of various patatin glycoproteins from plants. The patatin protein accounts for up to 40 of the total soluble protein in potato tubers. Patatin is a storage protein but it also has the enzymatic activity of lipid acyl hydrolase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
BYD2_k127_7784190_6	196162.Noca_1866	1.345e-133	436.0	28HGI@1|root,2Z7SC@2|Bacteria,2GKHQ@201174|Actinobacteria,4DPGV@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7784190_13	1121106.JQKB01000010_gene561	1.099e-47	195.0	COG2084@1|root,COG2084@2|Bacteria,1R889@1224|Proteobacteria,2TUEY@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_11,NAD_binding_2
BYD2_k127_7784190_3	1121933.AUHH01000009_gene894	1.379e-148	486.0	COG2197@1|root,COG2206@1|root,COG2197@2|Bacteria,COG2206@2|Bacteria,2GJS8@201174|Actinobacteria,4DT1D@85009|Propionibacteriales	201174|Actinobacteria	KT	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,HD,HD_5
BYD2_k127_7784190_16	405948.SACE_4115	6.55e-29	128.0	COG0596@1|root,COG0596@2|Bacteria,2IACG@201174|Actinobacteria,4EB6W@85010|Pseudonocardiales	201174|Actinobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_7784190_8	443218.AS9A_3072	1.106e-98	344.0	COG2267@1|root,COG2267@2|Bacteria,2GJUE@201174|Actinobacteria,23BIX@1762|Mycobacteriaceae	201174|Actinobacteria	I	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_7784190_1	1120950.KB892708_gene4380	0.0	1077.0	COG0474@1|root,COG0474@2|Bacteria,2GJJC@201174|Actinobacteria,4DPKG@85009|Propionibacteriales	201174|Actinobacteria	P	E1-E2 ATPase	-	-	-	ko:K12955	-	-	-	-	ko00000,ko01000	3.A.3.24	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
BYD2_k127_7784190_7	471852.Tcur_4795	2.053e-103	342.0	COG0637@1|root,COG0637@2|Bacteria	2|Bacteria	S	phosphonoacetaldehyde hydrolase activity	-	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2,Hydrolase
BYD2_k127_7784190_2	1385519.N801_12180	7.87e-158	516.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4FJVY@85021|Intrasporangiaceae	201174|Actinobacteria	G	Belongs to the FGGY kinase family	-	-	2.7.1.12	ko:K00851	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	-	R01737	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
BYD2_k127_7784190_0	1123392.AQWL01000002_gene1698	0.0	1104.0	COG0474@1|root,COG0474@2|Bacteria,1MUU5@1224|Proteobacteria,2VH2F@28216|Betaproteobacteria,1KS0K@119069|Hydrogenophilales	119069|Hydrogenophilales	P	Cation transporter/ATPase, N-terminus	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
BYD2_k127_7784190_15	857293.CAAU_1825	2.584e-35	156.0	COG2086@1|root,COG2086@2|Bacteria,1TQA0@1239|Firmicutes,247K9@186801|Clostridia,36EI7@31979|Clostridiaceae	186801|Clostridia	C	Electron transfer flavoprotein	etfB1	-	-	ko:K03521	-	-	-	-	ko00000	-	-	-	ETF
BYD2_k127_7784190_11	697303.Thewi_0618	1.582e-67	257.0	COG2025@1|root,COG2025@2|Bacteria,1TPC8@1239|Firmicutes,247NF@186801|Clostridia,42FKR@68295|Thermoanaerobacterales	186801|Clostridia	C	electron transfer flavoprotein, alpha subunit	etfA	-	1.3.1.108	ko:K03522,ko:K22432	-	-	-	-	ko00000,ko01000,ko04147	-	-	-	ETF,ETF_alpha
BYD2_k127_7784190_10	1449976.KALB_5609	2.444e-76	270.0	COG0394@1|root,COG0394@2|Bacteria,2IHR3@201174|Actinobacteria,4E43G@85010|Pseudonocardiales	201174|Actinobacteria	T	Low molecular weight phosphotyrosine protein phosphatase	-	-	1.20.4.1	ko:K03741	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
BYD2_k127_7784190_12	446470.Snas_2810	2.206e-56	206.0	COG0394@1|root,COG0640@1|root,COG0394@2|Bacteria,COG0640@2|Bacteria,2IB1N@201174|Actinobacteria	201174|Actinobacteria	K	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,LMWPc
BYD2_k127_7784190_5	1160718.SU9_25919	3.48e-138	456.0	COG1064@1|root,COG1064@2|Bacteria,2GNVQ@201174|Actinobacteria	201174|Actinobacteria	S	alcohol dehydrogenase	adhA	-	1.1.1.1	ko:K13953	ko00010,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_7784190_9	196162.Noca_2053	1.532e-78	265.0	COG2514@1|root,COG2514@2|Bacteria,2I4TW@201174|Actinobacteria	201174|Actinobacteria	S	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_7814825_0	1123024.AUII01000021_gene79	7.965e-299	924.0	COG1060@1|root,COG1060@2|Bacteria,2GK83@201174|Actinobacteria,4DX6M@85010|Pseudonocardiales	201174|Actinobacteria	H	Elongator protein 3, MiaB family, Radical SAM	-	-	2.5.1.77	ko:K11779	ko00680,ko01120,map00680,map01120	M00378	R09396	RC01381,RC03002,RC03007	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
BYD2_k127_7814825_4	273677.BW34_01905	1.581e-108	385.0	COG1611@1|root,COG1611@2|Bacteria,2GKJH@201174|Actinobacteria,4FMB4@85023|Microbacteriaceae	201174|Actinobacteria	S	Possible lysine decarboxylase	-	-	3.2.2.10	ko:K06966	ko00230,ko00240,map00230,map00240	-	R00182,R00510	RC00063,RC00318	ko00000,ko00001,ko01000	-	-	-	Lysine_decarbox
BYD2_k127_7814825_6	1313172.YM304_20280	4.297e-86	293.0	28IRH@1|root,2Z8QX@2|Bacteria,2GJW6@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7814825_1	1146883.BLASA_4994	6.383e-209	666.0	COG0366@1|root,COG0366@2|Bacteria,2GKS4@201174|Actinobacteria,4ERW2@85013|Frankiales	201174|Actinobacteria	G	SMART alpha amylase, catalytic sub domain	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	Alpha-amylase,DUF3459
BYD2_k127_7814825_10	1123320.KB889628_gene7906	2.367e-37	147.0	COG0454@1|root,COG0456@2|Bacteria	2|Bacteria	K	acetyltransferase	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_9
BYD2_k127_7814825_9	1229780.BN381_300018	1.658e-38	155.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,3UWY3@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
BYD2_k127_7814825_8	926560.KE387023_gene2224	7.292e-50	196.0	COG0500@1|root,COG2226@2|Bacteria	2|Bacteria	Q	methyltransferase	eryCVI	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983	2.1.1.234	ko:K13311,ko:K13326,ko:K21335	ko00523,ko01130,map00523,map01130	M00797,M00800	R06427,R11045,R11476	RC00003,RC01515,RC02262	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
BYD2_k127_7814825_5	1313172.YM304_20250	1.815e-107	362.0	COG0349@1|root,COG0349@2|Bacteria,2GKNM@201174|Actinobacteria,4CN02@84992|Acidimicrobiia	84992|Acidimicrobiia	J	3'-5' exonuclease	rnd	-	3.1.13.5	ko:K03684	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DNA_pol_A_exo1,HRDC
BYD2_k127_7814825_11	685727.REQ_34660	1.817e-25	108.0	COG0607@1|root,COG0607@2|Bacteria,2IQIP@201174|Actinobacteria,4G383@85025|Nocardiaceae	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
BYD2_k127_7814825_14	1313172.YM304_20230	2.687e-18	93.0	COG0746@1|root,COG0746@2|Bacteria	2|Bacteria	H	molybdenum cofactor guanylyltransferase activity	mobA	-	2.7.7.77,4.6.1.17	ko:K03637,ko:K03752,ko:K13818	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372,R11581	RC03425	ko00000,ko00001,ko01000	-	-	-	MobB,NTP_transf_3
BYD2_k127_7814825_2	1297742.A176_02025	1.629e-124	411.0	COG0076@1|root,COG0076@2|Bacteria,1MX25@1224|Proteobacteria,42NCK@68525|delta/epsilon subdivisions,2WMCF@28221|Deltaproteobacteria,2YTU4@29|Myxococcales	28221|Deltaproteobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
BYD2_k127_7814825_12	1382304.JNIL01000001_gene1710	1.183e-24	111.0	COG1853@1|root,COG1853@2|Bacteria,1V1X6@1239|Firmicutes,4HGJ2@91061|Bacilli,279EA@186823|Alicyclobacillaceae	91061|Bacilli	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
BYD2_k127_7814825_3	1229780.BN381_20030	1.012e-108	363.0	COG1075@1|root,COG1075@2|Bacteria,2IBAW@201174|Actinobacteria,3UXE9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Putative serine esterase (DUF676)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,DUF676,PGAP1
BYD2_k127_7814825_7	105422.BBPM01000003_gene5696	1.854e-59	211.0	COG0346@1|root,COG0346@2|Bacteria,2IHU2@201174|Actinobacteria,2NJWJ@228398|Streptacidiphilus	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7820919_5	471852.Tcur_4619	1.793e-94	316.0	COG1788@1|root,COG1788@2|Bacteria,2I9F6@201174|Actinobacteria,4EH0T@85012|Streptosporangiales	201174|Actinobacteria	I	Coenzyme A transferase	-	-	2.8.3.12	ko:K01039	ko00643,ko00650,ko01120,map00643,map00650,map01120	-	R04000,R05509	RC00012,RC00131,RC00137	ko00000,ko00001,ko01000	-	-	-	CoA_trans
BYD2_k127_7820919_2	471852.Tcur_4618	4.637e-114	388.0	COG1024@1|root,COG1024@2|Bacteria,2GN54@201174|Actinobacteria,4EIAR@85012|Streptosporangiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	echA20	-	4.2.1.17	ko:K01692	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00087	R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_7820919_4	1245471.PCA10_13800	2.163e-96	322.0	COG1028@1|root,COG1028@2|Bacteria,1P1U4@1224|Proteobacteria,1RR3M@1236|Gammaproteobacteria,1YJ2B@136841|Pseudomonas aeruginosa group	1236|Gammaproteobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_7820919_8	1313172.YM304_16250	4.436e-25	111.0	COG3794@1|root,COG3794@2|Bacteria	2|Bacteria	C	PFAM blue (type 1) copper domain protein	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cupredoxin_1
BYD2_k127_7820919_0	1229780.BN381_80366	1.427e-182	582.0	COG4677@1|root,COG4677@2|Bacteria,2I7VB@201174|Actinobacteria	201174|Actinobacteria	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix
BYD2_k127_7820919_6	1229780.BN381_80365	2.343e-92	317.0	28I5U@1|root,2Z890@2|Bacteria,2GKEB@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1996)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1996
BYD2_k127_7820919_7	1173023.KE650771_gene1475	2.939e-66	233.0	COG3467@1|root,COG3467@2|Bacteria,1G4RC@1117|Cyanobacteria,1JJWX@1189|Stigonemataceae	1117|Cyanobacteria	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	ko:K07005	-	-	-	-	ko00000	-	-	-	Pyridox_ox_2
BYD2_k127_7820919_1	1229780.BN381_10133	8.508e-125	417.0	COG1524@1|root,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	PE,Phosphodiest
BYD2_k127_7820919_3	749414.SBI_04793	7.953e-103	340.0	COG0667@1|root,COG0667@2|Bacteria,2GJ4R@201174|Actinobacteria	201174|Actinobacteria	C	aldo keto reductase	-	-	1.1.1.65	ko:K05275	ko00750,ko01100,ko01120,map00750,map01100,map01120	-	R01708	RC00116	ko00000,ko00001,ko01000	-	-	-	Aldo_ket_red
BYD2_k127_7848145_0	196162.Noca_4911	1.51e-267	831.0	COG0277@1|root,COG0277@2|Bacteria,2GK5U@201174|Actinobacteria,4DPV2@85009|Propionibacteriales	201174|Actinobacteria	C	PFAM FAD linked oxidase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BBE,FAD_binding_4
BYD2_k127_7848145_4	196162.Noca_4912	1.331e-137	439.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria,4DQI2@85009|Propionibacteriales	201174|Actinobacteria	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR,SCP2
BYD2_k127_7848145_45	457429.ABJI02000026_gene5757	5.496e-17	89.0	COG1708@1|root,COG1708@2|Bacteria,2IT8Y@201174|Actinobacteria	201174|Actinobacteria	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
BYD2_k127_7848145_12	591158.SSMG_01017	3.448e-95	318.0	COG1028@1|root,COG1028@2|Bacteria,2IB1P@201174|Actinobacteria	201174|Actinobacteria	IQ	Short-chain dehydrogenase reductase sdr	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_7848145_3	219305.MCAG_03383	2.849e-155	500.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria,4DB8J@85008|Micromonosporales	201174|Actinobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_7848145_55	1123023.JIAI01000008_gene1265	1.28e-06	54.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria,4ED6D@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_7848145_7	1122138.AQUZ01000066_gene4339	2.394e-128	424.0	COG2223@1|root,COG2223@2|Bacteria	2|Bacteria	P	nitrite transmembrane transporter activity	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
BYD2_k127_7848145_44	1123023.JIAI01000008_gene1265	1.292e-17	94.0	COG5660@1|root,COG5660@2|Bacteria,2GQSP@201174|Actinobacteria,4ED6D@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_7848145_14	1123023.JIAI01000008_gene1266	4.762e-84	289.0	COG1595@1|root,COG1595@2|Bacteria,2I9C1@201174|Actinobacteria,4E8J0@85010|Pseudonocardiales	201174|Actinobacteria	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7848145_22	1254432.SCE1572_37460	1.534e-58	214.0	COG0400@1|root,COG0400@2|Bacteria,1P51S@1224|Proteobacteria	1224|Proteobacteria	S	PFAM phospholipase Carboxylesterase	-	-	-	ko:K06999	-	-	-	-	ko00000	-	-	-	Abhydrolase_2
BYD2_k127_7848145_38	338966.Ppro_0730	1.08e-26	126.0	COG1051@1|root,COG1051@2|Bacteria,1QU0T@1224|Proteobacteria	1224|Proteobacteria	F	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage	nudH	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575	-	ko:K08311	ko03018,map03018	-	R10816	RC00002	ko00000,ko00001,ko01000,ko03019	-	-	-	NUDIX
BYD2_k127_7848145_20	1206101.AZXC01000019_gene1432	4.678e-63	234.0	COG2120@1|root,COG2120@2|Bacteria,2IDT2@201174|Actinobacteria	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	ko:K22135	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
BYD2_k127_7848145_8	28072.Nos7524_3474	2.1e-125	411.0	COG2519@1|root,COG2519@2|Bacteria,1GQ0A@1117|Cyanobacteria,1HSUX@1161|Nostocales	1117|Cyanobacteria	J	O-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
BYD2_k127_7848145_2	1146883.BLASA_3322	5.437e-187	620.0	COG3629@1|root,COG3903@1|root,COG3629@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria,4EUDE@85013|Frankiales	201174|Actinobacteria	K	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_22,BTAD,NB-ARC,Trans_reg_C
BYD2_k127_7848145_17	926560.KE387023_gene2757	1.671e-80	277.0	COG1028@1|root,COG1028@2|Bacteria,1WNJF@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	Fungal family of unknown function (DUF1776)	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_7848145_58	35754.JNYJ01000003_gene6534	0.0001227	51.0	28UI1@1|root,31V7R@2|Bacteria,2H6IC@201174|Actinobacteria,4DJH7@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7848145_25	1313172.YM304_07790	5.477e-56	220.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4CN19@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_7848145_28	1463825.JNXC01000022_gene532	3.544e-47	179.0	COG5485@1|root,COG5485@2|Bacteria	2|Bacteria	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
BYD2_k127_7848145_1	263358.VAB18032_27406	6.737e-249	785.0	COG5276@1|root,COG5276@2|Bacteria,2GMSY@201174|Actinobacteria,4D971@85008|Micromonosporales	201174|Actinobacteria	S	LVIVD repeat	-	-	-	-	-	-	-	-	-	-	-	-	LVIVD
BYD2_k127_7848145_35	1449976.KALB_3794	1.056e-28	134.0	COG2304@1|root,COG3537@1|root,COG2304@2|Bacteria,COG3537@2|Bacteria,2GKPD@201174|Actinobacteria,4DXJP@85010|Pseudonocardiales	201174|Actinobacteria	G	IgA Peptidase M64	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M64
BYD2_k127_7848145_29	263358.VAB18032_27411	6.096e-47	194.0	COG3544@1|root,COG3544@2|Bacteria,2IKUE@201174|Actinobacteria,4DE4C@85008|Micromonosporales	201174|Actinobacteria	S	Domain of unknown function (DUF4142)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
BYD2_k127_7848145_15	330214.NIDE0045	1.146e-82	293.0	COG0546@1|root,COG0546@2|Bacteria	2|Bacteria	S	glycolate biosynthetic process	-	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
BYD2_k127_7848145_21	298654.FraEuI1c_4287	6.272e-61	226.0	COG4585@1|root,COG4585@2|Bacteria,2GJEG@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HisKA_3
BYD2_k127_7848145_18	298654.FraEuI1c_4286	1.828e-77	278.0	COG2197@1|root,COG2197@2|Bacteria,2GJ46@201174|Actinobacteria	201174|Actinobacteria	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_7848145_16	105420.BBPO01000011_gene1963	9.353e-82	300.0	COG1131@1|root,COG1131@2|Bacteria,2GJBF@201174|Actinobacteria,2NHNG@228398|Streptacidiphilus	201174|Actinobacteria	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_7848145_30	1075090.GOAMR_64_00060	1.873e-43	171.0	COG0842@1|root,COG0842@2|Bacteria,2H2PR@201174|Actinobacteria	201174|Actinobacteria	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_7848145_26	2002.JOEQ01000006_gene1493	1.57e-55	202.0	COG1595@1|root,COG1595@2|Bacteria,2GMRK@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2,SnoaL_2
BYD2_k127_7848145_27	1122604.JONR01000020_gene457	2.339e-55	198.0	COG1247@1|root,COG1247@2|Bacteria,1RGU8@1224|Proteobacteria,1S791@1236|Gammaproteobacteria,1X65R@135614|Xanthomonadales	135614|Xanthomonadales	M	COG1247 Sortase and related acyltransferases	-	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
BYD2_k127_7848145_40	479433.Caci_7364	1.219e-25	117.0	COG0239@1|root,COG0239@2|Bacteria,2IKWG@201174|Actinobacteria	201174|Actinobacteria	D	Important for reducing fluoride concentration in the cell, thus reducing its toxicity	crcB	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
BYD2_k127_7848145_32	1246448.ANAZ01000008_gene2407	4.977e-39	160.0	COG1993@1|root,COG1993@2|Bacteria,2IM7J@201174|Actinobacteria,4EK9R@85012|Streptosporangiales	201174|Actinobacteria	S	Uncharacterized ACR, COG1993	-	-	-	ko:K09137	-	-	-	-	ko00000	-	-	-	DUF190
BYD2_k127_7848145_37	1449353.JQMQ01000005_gene628	1.056e-27	119.0	COG0239@1|root,COG0239@2|Bacteria,2IKM1@201174|Actinobacteria,2NIHG@228398|Streptacidiphilus	201174|Actinobacteria	D	CrcB-like protein, Camphor Resistance (CrcB)	crcB1	GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425	-	ko:K06199	-	-	-	-	ko00000,ko02000	1.A.43.1,1.A.43.2,1.A.43.3	-	-	CRCB
BYD2_k127_7848145_13	1137269.AZWL01000033_gene3330	3.932e-95	332.0	COG3612@1|root,COG3612@2|Bacteria,2GN7K@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7848145_46	234621.RER_22000	2.301e-13	79.0	COG1309@1|root,COG1309@2|Bacteria,2GVM5@201174|Actinobacteria,4FV7I@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_7848145_9	526225.Gobs_2962	9.753e-109	392.0	COG3004@1|root,COG3004@2|Bacteria,2GKIK@201174|Actinobacteria	201174|Actinobacteria	P	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons	nhaA	-	-	ko:K03313	-	-	-	-	ko00000,ko02000	2.A.33.1	-	-	Na_H_antiport_1
BYD2_k127_7848145_59	1056816.JAFQ01000004_gene6414	0.0005947	51.0	2DCZ6@1|root,2ZFW3@2|Bacteria,2I4NJ@201174|Actinobacteria	201174|Actinobacteria	S	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Trans_reg_C
BYD2_k127_7848145_41	645465.ACUR01000507_gene410	1.839e-21	106.0	COG0745@1|root,COG0745@2|Bacteria,2IQB8@201174|Actinobacteria	201174|Actinobacteria	KT	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Trans_reg_C
BYD2_k127_7848145_6	1094508.Tsac_2213	3.811e-132	439.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,42FEB@68295|Thermoanaerobacterales	186801|Clostridia	P	TIGRFAM Ammonium transporter	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp
BYD2_k127_7848145_39	525909.Afer_1930	1.133e-25	111.0	2EG9A@1|root,33A12@2|Bacteria,2GQ7U@201174|Actinobacteria,4CNB5@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7848145_34	1121382.JQKG01000023_gene1521	1.936e-32	130.0	COG2832@1|root,COG2832@2|Bacteria,1WK7X@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	S	Protein of unknown function (DUF454)	-	-	-	ko:K09790	-	-	-	-	ko00000	-	-	-	DUF454
BYD2_k127_7848145_11	1247963.JPHU01000008_gene2904	3.294e-99	339.0	COG2267@1|root,COG2267@2|Bacteria,1QDFI@1224|Proteobacteria,2U244@28211|Alphaproteobacteria	28211|Alphaproteobacteria	I	Protein of unknown function (DUF3089)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3089
BYD2_k127_7848145_10	390989.JOEG01000004_gene3785	1.014e-99	355.0	COG1893@1|root,COG1893@2|Bacteria,2GP6K@201174|Actinobacteria,4D9HN@85008|Micromonosporales	201174|Actinobacteria	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
BYD2_k127_7848145_5	37919.EP51_19505	3.215e-134	458.0	COG4941@1|root,COG4941@2|Bacteria,2GJ36@201174|Actinobacteria,4FVD0@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_7848145_24	1206744.BAGL01000055_gene1454	2.154e-56	207.0	COG3795@1|root,COG3795@2|Bacteria,2IQMR@201174|Actinobacteria,4G288@85025|Nocardiaceae	201174|Actinobacteria	S	YCII-related domain	-	-	-	-	-	-	-	-	-	-	-	-	YCII
BYD2_k127_7848145_43	644548.SCNU_12587	1.401e-18	102.0	COG2951@1|root,COG2951@2|Bacteria,2GX49@201174|Actinobacteria,4GGYH@85026|Gordoniaceae	201174|Actinobacteria	M	Transglycosylase SLT domain	-	-	-	-	-	-	-	-	-	-	-	-	SLT_2
BYD2_k127_7848145_33	1229780.BN381_220032	6.298e-33	150.0	COG1876@1|root,COG1876@2|Bacteria,2IQI8@201174|Actinobacteria	201174|Actinobacteria	M	peptidase M15B and M15C DD-carboxypeptidase VanY endolysin	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	B_lectin,VanY
BYD2_k127_7848145_48	106370.Francci3_3334	2.767e-10	73.0	COG2132@1|root,COG2132@2|Bacteria	2|Bacteria	Q	Multicopper oxidase	-	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Copper-bind,Cu-oxidase_2,Cu-oxidase_3
BYD2_k127_7848145_51	1449353.JQMQ01000005_gene5166	4.907e-08	63.0	COG1261@1|root,COG1261@2|Bacteria,2HIQE@201174|Actinobacteria,2NIRU@228398|Streptacidiphilus	201174|Actinobacteria	NO	Chaperone for flagella basal body P-ring formation	-	-	-	-	-	-	-	-	-	-	-	-	ChapFlgA,SAF
BYD2_k127_7848145_49	1463856.JOHY01000035_gene1829	3.481e-10	71.0	COG0455@1|root,COG0455@2|Bacteria,2HT5K@201174|Actinobacteria	201174|Actinobacteria	D	bacterial-type flagellum organization	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7848145_19	479435.Kfla_3292	9.646e-69	251.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4DWY1@85009|Propionibacteriales	201174|Actinobacteria	U	PFAM type II secretion system protein E	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
BYD2_k127_7848145_36	1095767.CAHD01000203_gene2330	3.58e-28	129.0	COG4965@1|root,COG4965@2|Bacteria,2GN6E@201174|Actinobacteria	201174|Actinobacteria	U	type II secretion system	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
BYD2_k127_7848145_31	1463856.JOHY01000035_gene1832	1.049e-39	168.0	COG2064@1|root,COG2064@2|Bacteria,2HZTC@201174|Actinobacteria	201174|Actinobacteria	NU	type II secretion system protein	-	-	-	-	-	-	-	-	-	-	-	-	T2SSF
BYD2_k127_7848145_56	1380354.JIAN01000009_gene3757	2.452e-06	55.0	COG4961@1|root,COG4961@2|Bacteria	2|Bacteria	U	PFAM TadE family protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
BYD2_k127_7848145_52	110319.CF8_1717	6.5e-08	63.0	COG4961@1|root,COG4961@2|Bacteria,2GRCJ@201174|Actinobacteria,4DSH3@85009|Propionibacteriales	201174|Actinobacteria	U	overlaps another CDS with the same product name	-	-	-	-	-	-	-	-	-	-	-	-	TadE
BYD2_k127_7848145_54	526225.Gobs_0677	4.425e-07	61.0	2E4ST@1|root,32ZM5@2|Bacteria,2GSCH@201174|Actinobacteria,4ETEF@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Tad
BYD2_k127_7848145_23	1380354.JIAN01000009_gene3760	1.287e-56	228.0	COG1652@1|root,COG1652@2|Bacteria,2I8YV@201174|Actinobacteria	201174|Actinobacteria	NU	PFAM Peptidoglycan-binding LysM	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,LysM
BYD2_k127_7864376_0	1313172.YM304_32130	1.288e-151	501.0	COG1236@1|root,COG1236@2|Bacteria,2HEXB@201174|Actinobacteria	201174|Actinobacteria	J	Beta-lactamase	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_2,RMMBL
BYD2_k127_7864376_1	1121878.AUGL01000015_gene3062	1.305e-50	185.0	COG3911@1|root,COG3911@2|Bacteria,1RBSG@1224|Proteobacteria,1S31D@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_28
BYD2_k127_7864432_5	580340.Tlie_1652	1.642e-13	84.0	COG1331@1|root,COG1331@2|Bacteria	2|Bacteria	O	Highly conserved protein containing a thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4861,Glyco_hydro_76
BYD2_k127_7864432_7	502025.Hoch_0322	5.584e-07	60.0	2E6S9@1|root,331CB@2|Bacteria,1QQT9@1224|Proteobacteria,43E0N@68525|delta/epsilon subdivisions,2X94D@28221|Deltaproteobacteria,2Z1UU@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7864432_4	1254432.SCE1572_11700	9.87e-62	232.0	2B8GZ@1|root,321S2@2|Bacteria,1PMCZ@1224|Proteobacteria,439VN@68525|delta/epsilon subdivisions,2X59R@28221|Deltaproteobacteria,2Z0AZ@29|Myxococcales	28221|Deltaproteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	VKG_Carbox
BYD2_k127_7864432_8	1122611.KB903940_gene1681	1.487e-06	57.0	COG5637@1|root,COG5637@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	BON,DUF2892,Polyketide_cyc,Polyketide_cyc2
BYD2_k127_7864432_6	543632.JOJL01000022_gene851	1.809e-07	64.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	ko:K17713	-	-	-	-	ko00000,ko02000	1.B.33.1	-	-	PQQ_2,PQQ_3
BYD2_k127_7864432_2	471852.Tcur_4621	1.515e-143	463.0	COG2070@1|root,COG2070@2|Bacteria,2GKA6@201174|Actinobacteria,4EG2Y@85012|Streptosporangiales	201174|Actinobacteria	S	Nitronate monooxygenase	fabK	GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003938,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0007623,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0012505,GO:0016192,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034404,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0042278,GO:0042451,GO:0042455,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046903,GO:0048511,GO:0050896,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097708,GO:0099503,GO:0101002,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1904813	1.13.12.16	ko:K00459	ko00910,map00910	-	R00025	RC02541,RC02759	ko00000,ko00001,ko01000	-	-	-	NMO
BYD2_k127_7864432_0	469383.Cwoe_2351	1.223e-176	562.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4CPSQ@84995|Rubrobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_7864432_3	365528.KB891251_gene5779	3.514e-98	337.0	COG1960@1|root,COG1960@2|Bacteria,2GKUW@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_N
BYD2_k127_7864432_1	1229780.BN381_350093	9.33e-172	544.0	COG0183@1|root,COG0183@2|Bacteria,2GJAC@201174|Actinobacteria,3UWHR@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
BYD2_k127_787570_15	35754.JNYJ01000003_gene6571	8.255e-30	130.0	COG1028@1|root,COG1028@2|Bacteria,2GW8A@201174|Actinobacteria,4DFCU@85008|Micromonosporales	201174|Actinobacteria	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_787570_14	196162.Noca_4010	2.004e-35	149.0	COG5517@1|root,COG5517@2|Bacteria	2|Bacteria	Q	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
BYD2_k127_787570_10	882086.SacxiDRAFT_2974	5.889e-66	239.0	COG3568@1|root,COG3568@2|Bacteria,2H3ST@201174|Actinobacteria,4DZR3@85010|Pseudonocardiales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_787570_13	1380347.JNII01000008_gene4091	9.682e-40	162.0	COG4405@1|root,COG4405@2|Bacteria	2|Bacteria	I	Protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	ASCH
BYD2_k127_787570_2	1146883.BLASA_0285	4.541e-180	572.0	COG1257@1|root,COG1257@2|Bacteria,2GP3P@201174|Actinobacteria	201174|Actinobacteria	I	reductase	mvaA	-	1.1.1.34	ko:K00021	ko00900,ko01100,ko01110,ko01130,ko04152,ko04976,map00900,map01100,map01110,map01130,map04152,map04976	M00095	R02082	RC00004,RC00644	ko00000,ko00001,ko00002,ko01000	-	-	-	HMG-CoA_red
BYD2_k127_787570_9	298654.FraEuI1c_5017	1.599e-76	263.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_787570_11	298654.FraEuI1c_5016	2.756e-61	224.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_787570_16	1502850.FG91_01889	5.939e-24	112.0	COG2017@1|root,COG2017@2|Bacteria,1RGXX@1224|Proteobacteria,2U93Z@28211|Alphaproteobacteria,2K56V@204457|Sphingomonadales	204457|Sphingomonadales	G	Aldose 1-epimerase	-	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
BYD2_k127_787570_5	644283.Micau_5047	1.019e-126	439.0	COG1070@1|root,COG1070@2|Bacteria,2GJDZ@201174|Actinobacteria,4D9ZD@85008|Micromonosporales	201174|Actinobacteria	G	Xylulose kinase	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
BYD2_k127_787570_3	1242864.D187_001888	2.641e-178	572.0	COG2115@1|root,COG2115@2|Bacteria,1MXS2@1224|Proteobacteria,438FH@68525|delta/epsilon subdivisions,2X3QH@28221|Deltaproteobacteria,2YWUI@29|Myxococcales	28221|Deltaproteobacteria	G	Belongs to the xylose isomerase family	xylA	-	5.3.1.5	ko:K01805	ko00040,ko00051,ko01100,map00040,map00051,map01100	-	R00878,R01432	RC00376,RC00516	ko00000,ko00001,ko01000	-	-	-	-
BYD2_k127_787570_0	1121946.AUAX01000035_gene6151	1.133e-292	936.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria,4DAVT@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 3 family	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
BYD2_k127_787570_6	1125971.ASJB01000064_gene6487	1.176e-123	425.0	COG1609@1|root,COG1609@2|Bacteria,2GJRG@201174|Actinobacteria,4DZ3G@85010|Pseudonocardiales	201174|Actinobacteria	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
BYD2_k127_787570_4	926569.ANT_28600	1.211e-137	451.0	COG1653@1|root,COG1653@2|Bacteria,2G72Y@200795|Chloroflexi	200795|Chloroflexi	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1
BYD2_k127_787570_7	397278.JOJN01000003_gene1680	9.206e-105	353.0	COG1175@1|root,COG1175@2|Bacteria,2GKJI@201174|Actinobacteria,4DP36@85009|Propionibacteriales	201174|Actinobacteria	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
BYD2_k127_787570_8	1121272.KB903283_gene5033	1.957e-99	332.0	COG0395@1|root,COG0395@2|Bacteria,2GNQW@201174|Actinobacteria,4D8QX@85008|Micromonosporales	201174|Actinobacteria	P	ABC-type sugar transport system, permease component	-	-	-	ko:K02026,ko:K10119,ko:K17243	ko02010,map02010	M00196,M00207,M00600	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28,3.A.1.1.39	-	-	BPD_transp_1
BYD2_k127_787570_1	1123024.AUII01000006_gene4713	2.258e-244	780.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4E1QR@85010|Pseudonocardiales	201174|Actinobacteria	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
BYD2_k127_787570_12	1449065.JMLL01000010_gene430	1.627e-60	214.0	COG3832@1|root,COG3832@2|Bacteria,1RD0P@1224|Proteobacteria,2U79U@28211|Alphaproteobacteria,43P8U@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	S	Activator of Hsp90 ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_787570_18	1040983.AXAE01000001_gene2665	8.57e-08	53.0	COG0640@1|root,COG0640@2|Bacteria,1N10H@1224|Proteobacteria,2UBRH@28211|Alphaproteobacteria	28211|Alphaproteobacteria	K	Transcriptional	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_7926290_1	1146883.BLASA_0339	3.191e-97	339.0	28IEF@1|root,2Z8GG@2|Bacteria,2I8UG@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_7926290_4	1121931.AUHG01000011_gene2344	1.922e-29	135.0	COG0463@1|root,COG0463@2|Bacteria,4NQ67@976|Bacteroidetes,1IJYC@117743|Flavobacteriia	976|Bacteroidetes	M	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_7926290_3	1193181.BN10_720044	7.014e-63	228.0	COG1216@1|root,COG1216@2|Bacteria,2I04I@201174|Actinobacteria,4FGGH@85021|Intrasporangiaceae	201174|Actinobacteria	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
BYD2_k127_7926290_0	326424.FRAAL2058	3.489e-157	507.0	COG0677@1|root,COG0677@2|Bacteria,2GK5K@201174|Actinobacteria,4ERD8@85013|Frankiales	201174|Actinobacteria	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.136,1.1.1.336	ko:K02472,ko:K13015	ko00520,ko05111,map00520,map05111	-	R00421,R03317	RC00291	ko00000,ko00001,ko01000,ko01005	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
BYD2_k127_7926290_2	1122917.KB899662_gene2150	6.672e-69	242.0	COG0451@1|root,COG0451@2|Bacteria,1V34Y@1239|Firmicutes,4HCJE@91061|Bacilli,26RRS@186822|Paenibacillaceae	91061|Bacilli	GM	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2,5.1.3.25	ko:K01784,ko:K17947	ko00052,ko00520,ko00523,ko01100,ko01130,map00052,map00520,map00523,map01100,map01130	M00361,M00362,M00632	R00291,R02984,R10279	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
BYD2_k127_7980081_0	1313172.YM304_36700	1.635e-111	378.0	COG0208@1|root,COG0208@2|Bacteria,2GKGZ@201174|Actinobacteria	201174|Actinobacteria	F	PFAM Fatty acid desaturase, type 2	desA	-	1.14.19.11,1.14.19.2,1.14.19.26	ko:K03921	ko00061,ko01040,ko01212,map00061,map01040,map01212	-	R03370,R08161,R11108,R11109	RC00917	ko00000,ko00001,ko01000,ko01004	-	-	-	FA_desaturase_2
BYD2_k127_7980081_1	1463895.JODA01000020_gene7664	1.503e-31	137.0	COG4758@1|root,COG4758@2|Bacteria,2I8FE@201174|Actinobacteria	201174|Actinobacteria	S	Domain of unknown function (DUF1707)	-	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	DUF1707,DUF2154
BYD2_k127_7984589_0	234267.Acid_5749	6.26e-138	465.0	COG0515@1|root,COG0823@1|root,COG0515@2|Bacteria,COG0823@2|Bacteria	2|Bacteria	U	Involved in the tonB-independent uptake of proteins	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PD40,Pkinase,WD40
BYD2_k127_8044329_9	644282.Deba_0890	0.0001081	53.0	COG2740@1|root,COG2740@2|Bacteria	2|Bacteria	K	Nucleic-acid-binding protein implicated in transcription termination	ylxR	-	-	ko:K02600,ko:K07742	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	DUF448
BYD2_k127_8044329_7	1229780.BN381_330070	9.68e-20	99.0	COG0532@1|root,COG0532@2|Bacteria,2GKPH@201174|Actinobacteria,3UW6W@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
BYD2_k127_8044329_8	290399.Arth_1415	7.428e-10	69.0	COG2740@1|root,COG2740@2|Bacteria,2GQH0@201174|Actinobacteria,1WA8F@1268|Micrococcaceae	201174|Actinobacteria	K	Protein of unknown function (DUF448)	-	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
BYD2_k127_8044329_2	1229780.BN381_330069	5.333e-156	517.0	COG0195@1|root,COG0195@2|Bacteria,2GJDJ@201174|Actinobacteria,3UW9A@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Participates in both transcription termination and antitermination	nusA	GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0040007,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
BYD2_k127_8044329_6	1229780.BN381_330068	4.434e-40	155.0	COG0779@1|root,COG0779@2|Bacteria,2I9BT@201174|Actinobacteria,3UWYK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Required for maturation of 30S ribosomal subunits	rimP	GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
BYD2_k127_8044329_0	298655.KI912266_gene1541	1.662e-212	682.0	COG0442@1|root,COG0442@2|Bacteria,2GJ9G@201174|Actinobacteria,4EUFB@85013|Frankiales	201174|Actinobacteria	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
BYD2_k127_8044329_10	67257.JODR01000015_gene5873	0.0001136	53.0	2ES34@1|root,33JN0@2|Bacteria,2GKCH@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8044329_1	1229780.BN381_330058	3.633e-196	642.0	COG0821@1|root,COG0821@2|Bacteria,2GK2S@201174|Actinobacteria,3UW9H@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030312,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901576	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	-	GcpE
BYD2_k127_8044329_4	1313172.YM304_27430	4.027e-69	253.0	COG0750@1|root,COG0750@2|Bacteria,2GJJT@201174|Actinobacteria,4CMZX@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Peptidase family M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
BYD2_k127_8044329_3	1121926.AXWO01000025_gene3878	2.305e-107	361.0	COG0743@1|root,COG0743@2|Bacteria,2GIRV@201174|Actinobacteria,4EY28@85014|Glycomycetales	201174|Actinobacteria	I	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal	dxr	GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0050897,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv2870c	DXPR_C,DXP_redisom_C,DXP_reductoisom
BYD2_k127_8044329_5	1229780.BN381_330055	9.685e-57	211.0	COG0575@1|root,COG0575@2|Bacteria,2I7ZA@201174|Actinobacteria,3UWMF@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Belongs to the CDS family	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
BYD2_k127_8067916_0	1313172.YM304_16240	4.705e-239	751.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4CNF1@84992|Acidimicrobiia	84992|Acidimicrobiia	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_8067916_6	1229780.BN381_80292	4.118e-41	162.0	COG3346@1|root,COG3346@2|Bacteria,2GR90@201174|Actinobacteria,3UWY7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	SURF1 family	-	GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704,GO:0071944	-	-	-	-	-	-	-	-	-	-	SURF1
BYD2_k127_8067916_8	561175.KB894093_gene2907	5.357e-14	79.0	COG1309@1|root,COG1309@2|Bacteria,2IPMI@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_8067916_7	58123.JOFJ01000021_gene3930	2.195e-23	108.0	COG1309@1|root,COG1309@2|Bacteria,2IPSV@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_8067916_2	1229780.BN381_80295	9.206e-167	546.0	COG0208@1|root,COG0208@2|Bacteria,2GJKZ@201174|Actinobacteria	201174|Actinobacteria	F	P-aminobenzoate N-oxygenase AurF	-	-	-	-	-	-	-	-	-	-	-	-	AurF
BYD2_k127_8067916_5	1869.MB27_06630	2.334e-43	167.0	2B34Q@1|root,31VSF@2|Bacteria,2I9DC@201174|Actinobacteria,4DEV7@85008|Micromonosporales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8067916_3	1313172.YM304_16390	1.451e-81	301.0	COG0329@1|root,COG0329@2|Bacteria,2GJ34@201174|Actinobacteria,4CN0H@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
BYD2_k127_8067916_1	1313172.YM304_16400	3.24e-226	715.0	COG0595@1|root,COG0595@2|Bacteria,2GIW7@201174|Actinobacteria,4CMS5@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Zn-dependent metallo-hydrolase RNA specificity domain	-	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,RMMBL
BYD2_k127_8067916_4	1229780.BN381_90081	1.137e-61	224.0	COG0266@1|root,COG0266@2|Bacteria,2GJNT@201174|Actinobacteria,3UWHS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	fpg	GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
BYD2_k127_8096040_2	656024.FsymDg_3075	3.63e-185	636.0	COG2114@1|root,COG2909@1|root,COG3899@1|root,COG2114@2|Bacteria,COG2909@2|Bacteria,COG3899@2|Bacteria,2GJAR@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,Guanylate_cyc,Trans_reg_C
BYD2_k127_8096040_0	1121385.AQXW01000004_gene3170	8.125e-212	676.0	COG0028@1|root,COG0028@2|Bacteria,2GN3X@201174|Actinobacteria	201174|Actinobacteria	EH	Belongs to the TPP enzyme family	ilvX	GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016020,GO:0016053,GO:0019752,GO:0030312,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
BYD2_k127_8096040_1	1229780.BN381_250059	7.459e-189	607.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,3UXBP@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	FAD linked oxidases, C-terminal domain	-	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_8096040_14	436308.Nmar_1468	8.699e-24	106.0	COG2154@1|root,arCOG02939@2157|Archaea,41SSQ@651137|Thaumarchaeota	651137|Thaumarchaeota	H	pterin-4-alpha-carbinolamine dehydratase	-	-	4.2.1.96	ko:K01724	ko00790,map00790	-	R04734	RC01208	ko00000,ko00001,ko01000,ko04147	-	-	-	Pterin_4a
BYD2_k127_8096040_10	1229780.BN381_210086	7.991e-65	226.0	COG0822@1|root,COG0822@2|Bacteria,2IHY9@201174|Actinobacteria,3UWVS@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NifU-like N terminal domain	sufU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
BYD2_k127_8096040_4	1313172.YM304_14820	2.598e-164	529.0	COG0520@1|root,COG0520@2|Bacteria,2GIVK@201174|Actinobacteria,4CMVJ@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine	-	-	2.8.1.7,4.4.1.16	ko:K11717	ko00450,ko01100,map00450,map01100	-	R03599,R11528	RC00961,RC01789,RC02313	ko00000,ko00001,ko01000	-	-	-	Aminotran_5
BYD2_k127_8096040_8	1121877.JQKF01000001_gene1317	4.906e-92	316.0	COG0396@1|root,COG0396@2|Bacteria,2GKB7@201174|Actinobacteria,4CMZ6@84992|Acidimicrobiia	84992|Acidimicrobiia	O	FeS assembly ATPase SufC	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
BYD2_k127_8096040_3	469371.Tbis_2856	8.13e-177	578.0	COG3408@1|root,COG3408@2|Bacteria,2GIUI@201174|Actinobacteria,4DXAD@85010|Pseudonocardiales	201174|Actinobacteria	G	Glycogen debranching enzyme	-	-	-	-	-	-	-	-	-	-	-	-	GDE_C,GDE_N_bis
BYD2_k127_8096040_6	1429046.RR21198_4520	7.354e-110	365.0	COG1656@1|root,COG1656@2|Bacteria,2GMQR@201174|Actinobacteria,4FZ3N@85025|Nocardiaceae	201174|Actinobacteria	T	Mut7-C ubiquitin	-	-	-	ko:K09122	-	-	-	-	ko00000	-	-	-	Mut7-C,Ub-Mut7C
BYD2_k127_8096040_11	101510.RHA1_ro05950	1.805e-60	219.0	2AP53@1|root,31E6R@2|Bacteria,2IPBQ@201174|Actinobacteria,4G5IK@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8096040_9	644283.Micau_4399	1.57e-83	298.0	COG0730@1|root,COG0730@2|Bacteria,2GNPE@201174|Actinobacteria,4D9HZ@85008|Micromonosporales	201174|Actinobacteria	S	membrane transporter protein	cysZ	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
BYD2_k127_8096040_7	1229780.BN381_210088	9.372e-96	319.0	COG0491@1|root,COG0491@2|Bacteria,2GKJA@201174|Actinobacteria,3UXGK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
BYD2_k127_8096040_13	1229780.BN381_210091	2.927e-38	151.0	COG1848@1|root,COG1848@2|Bacteria,2H8GW@201174|Actinobacteria	201174|Actinobacteria	S	PIN domain	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
BYD2_k127_8096040_15	1229780.BN381_210092	1.044e-12	73.0	COG4118@1|root,COG4118@2|Bacteria	2|Bacteria	D	positive regulation of growth	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
BYD2_k127_8096040_5	1229780.BN381_210093	9.882e-160	511.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,3UXCB@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_8097369_0	1123023.JIAI01000001_gene6343	1.197e-87	299.0	COG1028@1|root,COG1028@2|Bacteria,2GKVM@201174|Actinobacteria,4E3Q3@85010|Pseudonocardiales	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_8097369_1	1206729.BAFZ01000061_gene3733	2.148e-73	263.0	COG1396@1|root,COG1396@2|Bacteria,2GKRR@201174|Actinobacteria,4FZEW@85025|Nocardiaceae	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
BYD2_k127_8110833_1	37919.EP51_11225	1.055e-105	363.0	COG0480@1|root,COG0480@2|Bacteria,2GKRU@201174|Actinobacteria,4FXJM@85025|Nocardiaceae	201174|Actinobacteria	J	Elongation factor G, domain IV	fusA2	GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
BYD2_k127_8110833_3	1313172.YM304_19750	1.453e-67	240.0	COG0558@1|root,COG0558@2|Bacteria,2GYKW@201174|Actinobacteria,4CN1P@84992|Acidimicrobiia	84992|Acidimicrobiia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.5	ko:K00995	ko00564,ko01100,map00564,map01100	-	R01801	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
BYD2_k127_8110833_2	1229780.BN381_50175	9.158e-75	273.0	COG1560@1|root,COG1560@2|Bacteria,2GM7B@201174|Actinobacteria,3UXIQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Bacterial lipid A biosynthesis acyltransferase	htrB	GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509	2.3.1.265	ko:K22311	-	-	-	-	ko00000,ko01000	-	-	-	Lip_A_acyltrans
BYD2_k127_8110833_0	1313172.YM304_19780	6.546e-122	401.0	COG0438@1|root,COG0438@2|Bacteria,2GKQ8@201174|Actinobacteria,4CN3N@84992|Acidimicrobiia	84992|Acidimicrobiia	M	Glycosyl transferases group 1	-	-	2.4.1.345	ko:K08256	-	-	R11702	-	ko00000,ko01000,ko01003	-	GT4	-	Glyco_trans_1_4,Glyco_transf_4
BYD2_k127_8110833_4	78345.BMERY_1517	8.507e-07	51.0	COG1704@1|root,COG1704@2|Bacteria,2GPS4@201174|Actinobacteria,4CZE2@85004|Bifidobacteriales	201174|Actinobacteria	S	LemA family	lemA	-	-	ko:K03744	-	-	-	-	ko00000	-	-	-	LemA
BYD2_k127_8111769_6	761193.Runsl_2419	3.618e-50	201.0	COG0518@1|root,COG0518@2|Bacteria,4NTGJ@976|Bacteroidetes,47XUV@768503|Cytophagia	976|Bacteroidetes	F	Glutamine amidotransferase class-I	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase
BYD2_k127_8111769_2	1380394.JADL01000011_gene3947	1.484e-186	594.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2TRJV@28211|Alphaproteobacteria,2JP8V@204441|Rhodospirillales	204441|Rhodospirillales	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
BYD2_k127_8111769_5	670487.Ocepr_1975	1.358e-99	340.0	COG1028@1|root,COG1028@2|Bacteria,1WM8P@1297|Deinococcus-Thermus	1297|Deinococcus-Thermus	IQ	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
BYD2_k127_8111769_1	761193.Runsl_1927	6.03e-218	686.0	COG0174@1|root,COG0174@2|Bacteria,4NHET@976|Bacteroidetes,47M1X@768503|Cytophagia	976|Bacteroidetes	E	PFAM glutamine synthetase catalytic region	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
BYD2_k127_8111769_4	471852.Tcur_2561	1.935e-179	597.0	COG1070@1|root,COG1070@2|Bacteria,2GNCR@201174|Actinobacteria,4EPGJ@85012|Streptosporangiales	201174|Actinobacteria	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	2.7.1.17,2.7.1.215,2.7.1.53	ko:K00854,ko:K00862,ko:K00880	ko00040,ko00053,ko01100,map00040,map00053,map01100	M00014	R01639,R01901,R07127,R11536	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
BYD2_k127_8111769_0	1370120.AUWR01000008_gene527	5.242e-237	739.0	COG0076@1|root,COG0076@2|Bacteria,2GKIH@201174|Actinobacteria,23CIC@1762|Mycobacteriaceae	201174|Actinobacteria	E	Pyridoxal-dependent decarboxylase conserved domain	-	-	4.1.1.11,4.1.1.25,4.1.2.27	ko:K01634,ko:K18933	ko00350,ko00410,ko00600,ko00680,ko00770,ko01100,ko01110,ko04071,map00350,map00410,map00600,map00680,map00770,map01100,map01110,map04071	M00100	R00489,R00736,R02464,R06516	RC00264,RC00299,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
BYD2_k127_8111769_9	1206733.BAGC01000043_gene519	1.822e-44	171.0	COG3226@1|root,COG3226@2|Bacteria,2IMSE@201174|Actinobacteria,4G9TF@85025|Nocardiaceae	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_6,TetR_N
BYD2_k127_8111769_11	1231392.OCGS_1419	4.773e-24	113.0	COG1957@1|root,COG1957@2|Bacteria,1MUIW@1224|Proteobacteria,2TSXQ@28211|Alphaproteobacteria	28211|Alphaproteobacteria	F	COG1957 Inosine-uridine nucleoside N-ribohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
BYD2_k127_8111769_3	28444.JODQ01000007_gene5269	1.45e-184	586.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4EGQ4@85012|Streptosporangiales	201174|Actinobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
BYD2_k127_8111769_10	35754.JNYJ01000005_gene5489	6.783e-28	125.0	2CNK3@1|root,32SH9@2|Bacteria,2IRH1@201174|Actinobacteria,4DEV8@85008|Micromonosporales	201174|Actinobacteria	S	Protein of Unknown function (DUF2784)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2784
BYD2_k127_8111769_8	487521.OCU_09180	1.068e-44	170.0	COG2105@1|root,COG4195@1|root,COG2105@2|Bacteria,COG4195@2|Bacteria,2GU51@201174|Actinobacteria,235BA@1762|Mycobacteriaceae	201174|Actinobacteria	C	Replication protein	-	-	-	-	-	-	-	-	-	-	-	-	AIG2_2,GGACT,Gamma_PGA_hydro
BYD2_k127_8111769_7	436229.JOEH01000011_gene5405	4.742e-45	168.0	COG0346@1|root,COG0346@2|Bacteria,2HTBE@201174|Actinobacteria,2NMQ3@228398|Streptacidiphilus	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8140177_1	1229780.BN381_80206	7.994e-65	247.0	COG3273@1|root,COG3273@2|Bacteria	2|Bacteria	P	potassium ion transport	-	-	-	-	-	-	-	-	-	-	-	-	GntR,PhoU,TrkA_C
BYD2_k127_8140177_0	1229780.BN381_510003	5.04e-102	350.0	COG1824@1|root,COG1824@2|Bacteria,2H441@201174|Actinobacteria	201174|Actinobacteria	P	Integral membrane	-	-	-	-	-	-	-	-	-	-	-	-	MgtE
BYD2_k127_8140177_2	1463920.JOGB01000020_gene2262	5.454e-25	113.0	COG1881@1|root,COG1881@2|Bacteria,2IIR9@201174|Actinobacteria	201174|Actinobacteria	S	Phosphatidylethanolamine-binding protein	-	-	-	ko:K06910	-	-	-	-	ko00000	-	-	-	PBP
BYD2_k127_8140177_3	243233.MCA0713	8.889e-23	100.0	COG1254@1|root,COG1254@2|Bacteria,1N6NU@1224|Proteobacteria,1SCPF@1236|Gammaproteobacteria,1XFSQ@135618|Methylococcales	135618|Methylococcales	C	Acylphosphatase	-	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
BYD2_k127_8141036_2	795955.AFRW01000118_gene1308	2.77e-106	362.0	2CE4Q@1|root,2Z7WX@2|Bacteria,2H0P6@201174|Actinobacteria,1W81M@1268|Micrococcaceae	201174|Actinobacteria	S	Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2
BYD2_k127_8141036_0	593907.Celgi_0901	3.367e-290	906.0	COG0280@1|root,COG0857@1|root,COG0280@2|Bacteria,COG0857@2|Bacteria,2GJ5U@201174|Actinobacteria,4F0GJ@85016|Cellulomonadaceae	201174|Actinobacteria	C	belongs to the CobB CobQ family	pta	GO:0005575,GO:0005576	2.3.1.8	ko:K13788	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	AAA_26,DRTGG,PTA_PTB
BYD2_k127_8141036_1	1116232.AHBF01000047_gene2121	3.93e-145	466.0	COG1028@1|root,COG1028@2|Bacteria,2GKI2@201174|Actinobacteria	201174|Actinobacteria	IQ	short-chain dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short,adh_short_C2
BYD2_k127_8167614_10	521011.Mpal_1285	1.041e-07	60.0	COG3794@1|root,arCOG02929@2157|Archaea	2157|Archaea	C	PFAM blue (type 1) copper domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Copper-bind,Cupredoxin_1,GSDH
BYD2_k127_8167614_4	1313172.YM304_09420	5.889e-88	300.0	COG1321@1|root,COG1321@2|Bacteria,2GKMC@201174|Actinobacteria	201174|Actinobacteria	K	iron dependent repressor	ideR	GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005506,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006355,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009058,GO:0009237,GO:0009712,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0016151,GO:0018958,GO:0019184,GO:0019219,GO:0019222,GO:0019290,GO:0019540,GO:0019748,GO:0030145,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0044550,GO:0045892,GO:0045934,GO:0046870,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0050897,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141	-	ko:K03709	-	-	-	-	ko00000,ko03000	-	-	-	Fe_dep_repr_C,Fe_dep_repress,FeoA
BYD2_k127_8167614_1	1313172.YM304_15180	4.029e-116	392.0	COG1178@1|root,COG1178@2|Bacteria,2HFVM@201174|Actinobacteria,4CP3M@84992|Acidimicrobiia	84992|Acidimicrobiia	U	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02011	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1
BYD2_k127_8167614_2	1313172.YM304_15190	1.526e-94	321.0	COG1840@1|root,COG1840@2|Bacteria	2|Bacteria	P	iron ion homeostasis	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	SBP_bac_1,SBP_bac_11,SBP_bac_6,SBP_bac_8
BYD2_k127_8167614_8	471853.Bcav_4100	1.813e-44	166.0	2EK7B@1|root,33DXQ@2|Bacteria,2IJRP@201174|Actinobacteria	201174|Actinobacteria	S	DoxX-like family	-	-	-	-	-	-	-	-	-	-	-	-	DoxX_2
BYD2_k127_8167614_3	1121272.KB903254_gene6728	4.029e-88	304.0	COG3842@1|root,COG3842@2|Bacteria,2GJCM@201174|Actinobacteria,4DCIX@85008|Micromonosporales	201174|Actinobacteria	P	TOBE domain	fbpC	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
BYD2_k127_8167614_7	404589.Anae109_0093	8.692e-48	182.0	COG2227@1|root,COG2227@2|Bacteria,1QTWG@1224|Proteobacteria,42XHD@68525|delta/epsilon subdivisions,2WT8V@28221|Deltaproteobacteria	28221|Deltaproteobacteria	H	PFAM Methyltransferase type	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
BYD2_k127_8167614_6	404589.Anae109_0092	4.693e-60	224.0	COG1215@1|root,COG1215@2|Bacteria,1RJNP@1224|Proteobacteria,42ST7@68525|delta/epsilon subdivisions,2X7I3@28221|Deltaproteobacteria,2Z24R@29|Myxococcales	28221|Deltaproteobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_8167614_5	1313172.YM304_25150	1.123e-67	263.0	28TMQ@1|root,3459Q@2|Bacteria,2H8NA@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8167614_0	1068980.ARVW01000001_gene6755	7.391e-138	468.0	COG3973@1|root,COG3973@2|Bacteria,2GK30@201174|Actinobacteria,4DYSY@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA helicase	-	-	-	-	-	-	-	-	-	-	-	-	AAA_19,UvrD_C_2,Viral_helicase1
BYD2_k127_8167614_9	390989.JOEG01000002_gene4292	3.612e-15	87.0	COG0407@1|root,COG0407@2|Bacteria,2GMY6@201174|Actinobacteria,4D8XC@85008|Micromonosporales	201174|Actinobacteria	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	hemE	GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
BYD2_k127_8180029_45	28444.JODQ01000018_gene7285	3.201e-38	157.0	COG2242@1|root,COG2242@2|Bacteria	2|Bacteria	H	protein methyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_21
BYD2_k127_8180029_64	1303692.SFUL_1266	3.242e-08	60.0	2C50P@1|root,339UF@2|Bacteria,2GSCF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8180029_20	1214101.BN159_6192	2.084e-97	353.0	COG0790@1|root,COG0790@2|Bacteria,2GKCE@201174|Actinobacteria	201174|Actinobacteria	KLT	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1,TPR_10,TPR_16,TPR_4
BYD2_k127_8180029_54	479431.Namu_2023	2.777e-25	124.0	2DW3A@1|root,33YCP@2|Bacteria,2GZ8M@201174|Actinobacteria,4EVKN@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	-	-	-	-	-	-	-	-	-	-	-	-	RskA
BYD2_k127_8180029_21	1313172.YM304_29040	5.062e-96	327.0	COG0697@1|root,COG0697@2|Bacteria,2GK49@201174|Actinobacteria,4CNC2@84992|Acidimicrobiia	84992|Acidimicrobiia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
BYD2_k127_8180029_16	1386969.AWTB01000010_gene3965	5.269e-126	411.0	COG0596@1|root,COG0596@2|Bacteria,2I3HY@201174|Actinobacteria,4GH7M@85026|Gordoniaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
BYD2_k127_8180029_29	710685.MycrhN_5027	8.455e-64	225.0	COG0500@1|root,COG2226@2|Bacteria,2IGKC@201174|Actinobacteria,238UQ@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
BYD2_k127_8180029_58	326424.FRAAL5629	2.628e-18	90.0	COG0789@1|root,COG0789@2|Bacteria,2GKTU@201174|Actinobacteria,4EVE6@85013|Frankiales	201174|Actinobacteria	K	redox-sensitive transcriptional activator SoxR	soxR	-	-	ko:K13639	-	-	-	-	ko00000,ko03000	-	-	-	MerR,MerR-DNA-bind,MerR_1
BYD2_k127_8180029_19	1448389.BAVQ01000025_gene1257	3.693e-101	343.0	COG1028@1|root,COG1028@2|Bacteria,2HWDM@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_8180029_10	1229780.BN381_130390	9.384e-164	526.0	COG0399@1|root,COG0399@2|Bacteria,2GKD7@201174|Actinobacteria	201174|Actinobacteria	E	Belongs to the DegT DnrJ EryC1 family	-	-	1.17.1.1,4.2.1.164	ko:K12452,ko:K13328	ko00520,ko00523,ko01130,map00520,map00523,map01130	M00802	R03391,R03392,R08930	RC00230,RC00704	ko00000,ko00001,ko00002,ko01000	-	-	-	DegT_DnrJ_EryC1
BYD2_k127_8180029_3	1229780.BN381_10328	4.458e-191	607.0	COG1020@1|root,COG1020@2|Bacteria,2HEFF@201174|Actinobacteria,3UX6E@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	Q	Protein of unknown function (DUF1298)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1298,WES_acyltransf
BYD2_k127_8180029_38	222534.KB893742_gene2804	3.227e-54	193.0	COG1764@1|root,COG1764@2|Bacteria,2IID0@201174|Actinobacteria	201174|Actinobacteria	O	organic hydroperoxide resistance protein	ohr	-	-	-	-	-	-	-	-	-	-	-	OsmC
BYD2_k127_8180029_43	1077144.AGFF01000003_gene2327	2.192e-41	157.0	COG1846@1|root,COG1846@2|Bacteria,2IMA9@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MarR
BYD2_k127_8180029_14	1282876.BAOK01000001_gene3625	2.609e-143	465.0	COG2141@1|root,COG2141@2|Bacteria,1MX64@1224|Proteobacteria,2U6SB@28211|Alphaproteobacteria,4BTBH@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_8180029_48	1282876.BAOK01000001_gene3627	4.456e-35	143.0	COG2050@1|root,COG2050@2|Bacteria,1REK6@1224|Proteobacteria,2U8H6@28211|Alphaproteobacteria	28211|Alphaproteobacteria	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
BYD2_k127_8180029_13	419947.MRA_1542	5.544e-145	475.0	COG1063@1|root,COG1063@2|Bacteria,2GKBE@201174|Actinobacteria,236FJ@1762|Mycobacteriaceae	201174|Actinobacteria	C	alcohol dehydrogenase	adh	-	1.1.1.1,1.1.1.14	ko:K00001,ko:K00008	ko00010,ko00040,ko00051,ko00071,ko00350,ko00625,ko00626,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00051,map00071,map00350,map00625,map00626,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01220	M00014	R00623,R00754,R00875,R01896,R02124,R04805,R04880,R05233,R05234,R06917,R06927,R07105,R08281,R08306,R08310	RC00050,RC00085,RC00087,RC00088,RC00099,RC00102,RC00116,RC00649,RC01734,RC02273	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_8180029_26	1313172.YM304_16660	1.465e-73	254.0	COG0778@1|root,COG0778@2|Bacteria,2HI8Q@201174|Actinobacteria	201174|Actinobacteria	C	Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
BYD2_k127_8180029_4	67373.JOBF01000002_gene1336	1.501e-187	598.0	COG1249@1|root,COG1249@2|Bacteria,2GJJK@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_dim
BYD2_k127_8180029_18	1122609.AUGT01000013_gene4105	7.219e-102	363.0	COG2909@1|root,COG2909@2|Bacteria,2I50W@201174|Actinobacteria,4DPMG@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	ko:K03556	-	-	-	-	ko00000,ko03000	-	-	-	AAA_16,GerE
BYD2_k127_8180029_46	436229.JOEH01000016_gene7349	8.119e-37	143.0	2AY0M@1|root,32Z2S@2|Bacteria,2I859@201174|Actinobacteria,2NIUJ@228398|Streptacidiphilus	201174|Actinobacteria	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N,SHOCT
BYD2_k127_8180029_66	1033730.CAHG01000016_gene543	1.155e-05	52.0	2EIST@1|root,33CI4@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8180029_60	345341.KUTG_00465	7.401e-15	79.0	2EC60@1|root,3364M@2|Bacteria,2GR61@201174|Actinobacteria	201174|Actinobacteria	S	2TM domain	-	-	-	-	-	-	-	-	-	-	-	-	2TM
BYD2_k127_8180029_49	1380347.JNII01000005_gene3099	6.47e-34	136.0	2D19V@1|root,32TA6@2|Bacteria,2IRPX@201174|Actinobacteria,4ETBE@85013|Frankiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8180029_23	1229780.BN381_50164	1.106e-91	318.0	28MY8@1|root,2ZB54@2|Bacteria,2GMYY@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8180029_27	1429046.RR21198_1978	4.665e-66	232.0	2CXR2@1|root,32T2F@2|Bacteria,2I2M0@201174|Actinobacteria,4G1R1@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8180029_50	1429046.RR21198_1977	1.412e-33	131.0	2E35Q@1|root,32Y5M@2|Bacteria,2GS2Q@201174|Actinobacteria,4G39Q@85025|Nocardiaceae	201174|Actinobacteria	S	Short C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SHOCT
BYD2_k127_8180029_31	1123322.KB904658_gene1355	1.033e-58	213.0	COG1309@1|root,COG1309@2|Bacteria,2IKQ8@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_8180029_41	1237500.ANBA01000004_gene2160	2.775e-43	163.0	COG3467@1|root,COG3467@2|Bacteria,2IR80@201174|Actinobacteria,4EQ3W@85012|Streptosporangiales	201174|Actinobacteria	S	Pfam:Pyridox_oxidase	-	-	-	ko:K05558	-	-	-	-	ko00000	-	-	-	Putative_PNPOx
BYD2_k127_8180029_63	717605.Theco_2847	1.279e-09	71.0	COG2010@1|root,COG2010@2|Bacteria,1VEEP@1239|Firmicutes,4HP6N@91061|Bacilli,26ZR6@186822|Paenibacillaceae	91061|Bacilli	C	Cytochrome C oxidase, cbb3-type, subunit III	cccB	-	-	ko:K12263	-	-	-	-	ko00000	-	-	-	Cytochrome_CBB3
BYD2_k127_8180029_30	1157637.KB892091_gene5518	1.93e-61	235.0	COG1520@1|root,COG3420@1|root,COG1520@2|Bacteria,COG3420@2|Bacteria,2IAZ2@201174|Actinobacteria	201174|Actinobacteria	KLT	PQQ enzyme repeat	-	-	1.1.2.6,2.7.11.1	ko:K05889,ko:K12132	-	-	R03136	-	ko00000,ko01000,ko01001	-	-	-	PQQ,PQQ_2,PQQ_3,Pkinase
BYD2_k127_8180029_44	1108045.GORHZ_206_00370	1.139e-38	150.0	COG4635@1|root,COG4635@2|Bacteria,2IQCQ@201174|Actinobacteria	201174|Actinobacteria	CH	Flavodoxin domain	-	-	1.3.5.3	ko:K00230	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R09489	RC00885	ko00000,ko00001,ko00002,ko01000	-	-	-	Flavodoxin_5
BYD2_k127_8180029_9	1123024.AUII01000015_gene3750	3.327e-169	543.0	COG0654@1|root,COG0654@2|Bacteria,2GK7I@201174|Actinobacteria,4DXC9@85010|Pseudonocardiales	201174|Actinobacteria	CH	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FAD_binding_3,FAD_oxidored
BYD2_k127_8180029_0	1123024.AUII01000015_gene3749	2.51e-269	847.0	COG2909@1|root,COG2909@2|Bacteria	2|Bacteria	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Abhydrolase_1,GerE,Trans_reg_C
BYD2_k127_8180029_62	414996.IL38_23285	1.216e-12	76.0	COG3324@1|root,COG3324@2|Bacteria,2GPAS@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
BYD2_k127_8180029_55	469383.Cwoe_3000	1.474e-21	103.0	COG3324@1|root,COG3324@2|Bacteria,2GPAS@201174|Actinobacteria	201174|Actinobacteria	E	translation initiation factor activity	-	-	-	ko:K06996	-	-	-	-	ko00000	-	-	-	Glyoxalase
BYD2_k127_8180029_52	1313172.YM304_01240	7.67e-30	137.0	COG1848@1|root,COG1848@2|Bacteria,2IQB5@201174|Actinobacteria	201174|Actinobacteria	S	Toxic component of a toxin-antitoxin (TA) module. An RNase	-	-	-	ko:K07064	-	-	-	-	ko00000	-	-	-	PIN
BYD2_k127_8180029_65	298655.KI912266_gene5583	1.072e-05	49.0	COG4118@1|root,COG4118@2|Bacteria,2GQNI@201174|Actinobacteria,4EW86@85013|Frankiales	201174|Actinobacteria	D	Antitoxin Phd_YefM, type II toxin-antitoxin system	-	-	-	-	-	-	-	-	-	-	-	-	PhdYeFM_antitox
BYD2_k127_8180029_17	33876.JNXY01000021_gene4782	1.079e-105	353.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_8180029_39	886293.Sinac_1505	2.02e-53	202.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	waaD	-	2.4.1.56	ko:K00713,ko:K03280	ko00540,ko01100,map00540,map01100	M00080	R01996	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003,ko01005	-	GT4,GT9	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_8180029_57	33876.JNXY01000021_gene4781	7.942e-19	100.0	COG0720@1|root,COG0720@2|Bacteria	2|Bacteria	H	synthase	-	-	4.1.2.50,4.2.3.12	ko:K01737	ko00790,ko01100,map00790,map01100	M00842,M00843	R04286,R09959	RC01117,RC02846,RC02847	ko00000,ko00001,ko00002,ko01000,ko03016	-	-	-	PTPS
BYD2_k127_8180029_22	33876.JNXY01000021_gene4780	4.756e-92	313.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4DBD5@85008|Micromonosporales	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	3HCDH_N
BYD2_k127_8180029_8	710686.Mycsm_01466	5.638e-170	565.0	COG0807@1|root,COG1985@1|root,COG0807@2|Bacteria,COG1985@2|Bacteria,2I3VK@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate	ribA	-	3.5.4.25,4.1.99.12	ko:K01497,ko:K14652	ko00740,ko00790,ko01100,ko01110,ko02024,map00740,map00790,map01100,map01110,map02024	M00125,M00840	R00425,R07281	RC00293,RC01792,RC01815,RC02504	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydro2,RibD_C
BYD2_k127_8180029_6	1210045.ALNP01000018_gene2203	1.329e-174	579.0	COG1233@1|root,COG1233@2|Bacteria,2GJ80@201174|Actinobacteria	201174|Actinobacteria	Q	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase,NAD_binding_8
BYD2_k127_8180029_56	1283299.AUKG01000001_gene3477	3.311e-21	102.0	COG3832@1|root,COG3832@2|Bacteria,2IKZ7@201174|Actinobacteria	201174|Actinobacteria	S	polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_8180029_40	1157637.KB892117_gene8	3.188e-47	191.0	COG1028@1|root,COG1028@2|Bacteria,2I32I@201174|Actinobacteria	201174|Actinobacteria	IQ	Belongs to the short-chain dehydrogenases reductases (SDR) family	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_8180029_53	68170.KL590474_gene6009	2.136e-27	126.0	2DPE5@1|root,331QG@2|Bacteria,2IQE8@201174|Actinobacteria,4E5S3@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8180029_33	1121933.AUHH01000006_gene699	1.455e-58	207.0	COG2259@1|root,COG2259@2|Bacteria,2IJ0I@201174|Actinobacteria,4DRJ9@85009|Propionibacteriales	201174|Actinobacteria	S	DoxX	-	-	-	ko:K15977	-	-	-	-	ko00000	-	-	-	DoxX
BYD2_k127_8180029_2	994479.GL877878_gene1378	2.681e-247	774.0	COG1793@1|root,COG3285@1|root,COG1793@2|Bacteria,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,4E23I@85010|Pseudonocardiales	201174|Actinobacteria	L	DNA polymerase Ligase (LigD)	-	-	6.5.1.1	ko:K01971	ko03450,map03450	-	R00381	RC00005	ko00000,ko00001,ko01000,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
BYD2_k127_8180029_34	1380356.JNIK01000017_gene3059	4.513e-56	204.0	COG2267@1|root,COG2267@2|Bacteria,2IS9U@201174|Actinobacteria,4EWCQ@85013|Frankiales	201174|Actinobacteria	I	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_8180029_47	1054860.KB913030_gene5159	2.301e-35	149.0	COG0500@1|root,COG2226@2|Bacteria,2GRM0@201174|Actinobacteria	201174|Actinobacteria	Q	o-methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Dimerisation2,Methyltransf_2
BYD2_k127_8180029_25	861299.J421_2270	2.431e-74	285.0	COG0366@1|root,COG1524@1|root,COG0366@2|Bacteria,COG1524@2|Bacteria	2|Bacteria	S	mannose-ethanolamine phosphotransferase activity	-	-	3.2.1.1	ko:K01176,ko:K21571	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,CBM26,CBM53,CBM_20,Hemopexin,PglZ,SusE,SusF_SusE
BYD2_k127_8180029_1	35754.JNYJ01000032_gene1785	2.628e-264	859.0	COG0366@1|root,COG1523@1|root,COG0366@2|Bacteria,COG1523@2|Bacteria,2GKK1@201174|Actinobacteria,4DB3P@85008|Micromonosporales	201174|Actinobacteria	G	Belongs to the glycosyl hydrolase 13 family	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,CBM_48,DUF3372,PUD
BYD2_k127_8180029_59	290397.Adeh_2634	2.293e-17	96.0	COG5002@1|root,COG5002@2|Bacteria,1R5EN@1224|Proteobacteria,43CCF@68525|delta/epsilon subdivisions,2X60X@28221|Deltaproteobacteria,2Z384@29|Myxococcales	28221|Deltaproteobacteria	T	Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain)	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
BYD2_k127_8180029_51	1298863.AUEP01000001_gene1009	3.867e-33	143.0	COG2197@1|root,COG2197@2|Bacteria,2INB6@201174|Actinobacteria,4DUM5@85009|Propionibacteriales	201174|Actinobacteria	T	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
BYD2_k127_8180029_67	1380370.JIBA01000003_gene2727	5.166e-05	55.0	COG3847@1|root,COG3847@2|Bacteria,2GX2Y@201174|Actinobacteria	201174|Actinobacteria	U	PFAM Flp Fap pilin component	-	-	-	ko:K02651	ko04112,map04112	-	-	-	ko00000,ko00001,ko02035,ko02044	-	-	-	Flp_Fap
BYD2_k127_8180029_61	1292020.H483_0115390	3.029e-14	82.0	COG4961@1|root,COG4961@2|Bacteria,2IS3K@201174|Actinobacteria	201174|Actinobacteria	U	TadE-like protein	-	-	-	-	-	-	-	-	-	-	-	-	TadE
BYD2_k127_8180029_36	68170.KL590477_gene2205	6.104e-55	208.0	COG4655@1|root,COG4655@2|Bacteria,2IGK1@201174|Actinobacteria	201174|Actinobacteria	S	Putative Flp pilus-assembly TadE/G-like	-	-	-	-	-	-	-	-	-	-	-	-	Tad
BYD2_k127_8180029_42	1380356.JNIK01000021_gene4563	2.679e-42	165.0	COG3745@1|root,COG3745@2|Bacteria,2INHS@201174|Actinobacteria	201174|Actinobacteria	U	Pilus assembly protein	-	-	-	ko:K02279	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	RcpC,SAF
BYD2_k127_8180029_28	1380393.JHVP01000003_gene1143	5.451e-66	252.0	COG4963@1|root,COG4963@2|Bacteria,2GNHI@201174|Actinobacteria,4EVMD@85013|Frankiales	201174|Actinobacteria	D	Evidence 2b Function of strongly homologous gene	flpE	-	-	ko:K02282	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	AAA_31,CbiA,ParA
BYD2_k127_8180029_5	685727.REQ_18410	2.444e-180	575.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4FUYS@85025|Nocardiaceae	201174|Actinobacteria	U	Type II/IV secretion system protein	flpF	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
BYD2_k127_8180029_24	685727.REQ_18420	2.191e-81	301.0	COG2304@1|root,COG4965@1|root,COG2304@2|Bacteria,COG4965@2|Bacteria,2H577@201174|Actinobacteria	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF,VWA_2
BYD2_k127_8180029_37	1122609.AUGT01000012_gene4249	9.849e-55	203.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4DR34@85009|Propionibacteriales	201174|Actinobacteria	NU	Type II secretion system	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
BYD2_k127_8180029_32	1172188.KB911821_gene1362	1.102e-58	216.0	COG0305@1|root,COG0305@2|Bacteria,2I9NH@201174|Actinobacteria,4FER9@85021|Intrasporangiaceae	201174|Actinobacteria	L	KaiC	-	-	-	-	-	-	-	-	-	-	-	-	DnaB_C
BYD2_k127_8180029_11	710686.Mycsm_03836	3.256e-158	523.0	COG1082@1|root,COG1082@2|Bacteria,2GK1S@201174|Actinobacteria,23636@1762|Mycobacteriaceae	201174|Actinobacteria	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
BYD2_k127_8180029_15	1380390.JIAT01000013_gene203	8.562e-142	460.0	COG0673@1|root,COG0673@2|Bacteria,2HEV8@201174|Actinobacteria,4CSXU@84995|Rubrobacteria	84995|Rubrobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
BYD2_k127_8180029_12	266117.Rxyl_0399	6.737e-150	484.0	COG1940@1|root,COG1940@2|Bacteria,2GJ2S@201174|Actinobacteria,4CSEI@84995|Rubrobacteria	84995|Rubrobacteria	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2,ROK
BYD2_k127_8180029_7	1380390.JIAT01000013_gene201	7.089e-174	577.0	COG1129@1|root,COG1129@2|Bacteria,2GJ3F@201174|Actinobacteria,4CP7R@84995|Rubrobacteria	201174|Actinobacteria	P	PFAM ABC transporter related	rbsA1	-	3.6.3.17	ko:K10441	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	ABC_tran
BYD2_k127_8180029_35	1380390.JIAT01000013_gene200	3.409e-55	207.0	COG1172@1|root,COG1172@2|Bacteria,2GJDW@201174|Actinobacteria,4CQ95@84995|Rubrobacteria	84995|Rubrobacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
BYD2_k127_8256658_3	710686.Mycsm_06053	1.648e-95	317.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23CU1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Creatinase/Prolidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
BYD2_k127_8256658_5	1299327.I546_3512	1.012e-86	309.0	COG0006@1|root,COG0006@2|Bacteria,2H45Q@201174|Actinobacteria,23D5F@1762|Mycobacteriaceae	201174|Actinobacteria	E	Metallopeptidase family M24	-	-	-	-	-	-	-	-	-	-	-	-	Creatinase_N,Peptidase_M24
BYD2_k127_8256658_1	487521.OCU_21610	1.404e-135	462.0	COG2124@1|root,COG2124@2|Bacteria,2I2QQ@201174|Actinobacteria,236CF@1762|Mycobacteriaceae	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_8256658_8	1278073.MYSTI_04829	6.125e-43	168.0	COG2159@1|root,COG2159@2|Bacteria,1MUUR@1224|Proteobacteria	1224|Proteobacteria	K	amidohydrolase	bamU	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
BYD2_k127_8256658_2	1160137.KB907307_gene1934	3.265e-120	398.0	COG2159@1|root,COG2159@2|Bacteria,2GMRC@201174|Actinobacteria,4FZGH@85025|Nocardiaceae	201174|Actinobacteria	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_8256658_0	471852.Tcur_2177	4.423e-212	682.0	COG1960@1|root,COG1960@2|Bacteria,2GKVN@201174|Actinobacteria,4EFXA@85012|Streptosporangiales	201174|Actinobacteria	I	PFAM acyl-CoA dehydrogenase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_8256658_4	1223544.GSI01S_45_00170	1.479e-87	308.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,4GDAF@85026|Gordoniaceae	201174|Actinobacteria	IQ	AMP-binding enzyme C-terminal domain	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_8256658_9	298654.FraEuI1c_3297	2.883e-40	166.0	COG0346@1|root,COG0346@2|Bacteria,2IFSX@201174|Actinobacteria	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase,Glyoxalase_4
BYD2_k127_8256658_6	298654.FraEuI1c_4590	4.836e-56	212.0	COG1309@1|root,COG1309@2|Bacteria,2IFV0@201174|Actinobacteria	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_8256658_7	710421.Mycch_2954	1.745e-46	171.0	COG1545@1|root,COG1545@2|Bacteria,2II25@201174|Actinobacteria,23A1J@1762|Mycobacteriaceae	201174|Actinobacteria	S	nucleic-acid-binding protein containing a Zn-ribbon	-	-	-	ko:K07068	-	-	-	-	ko00000	-	-	-	DUF35_N,OB_aCoA_assoc
BYD2_k127_8256658_10	710421.Mycch_2953	3.115e-39	151.0	COG0183@1|root,COG0183@2|Bacteria,2GKH4@201174|Actinobacteria,2341M@1762|Mycobacteriaceae	201174|Actinobacteria	I	Acetyl-CoA acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8278203_3	1463821.JOGR01000008_gene2065	3.422e-66	227.0	COG1117@1|root,COG1117@2|Bacteria,2GJQ3@201174|Actinobacteria,4EXWB@85014|Glycomycetales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
BYD2_k127_8278203_5	754252.PFREUD_18800	1.229e-16	92.0	COG0704@1|root,COG0704@2|Bacteria,2GKAD@201174|Actinobacteria,4DQEB@85009|Propionibacteriales	201174|Actinobacteria	P	Plays a role in the regulation of phosphate uptake	phoU	-	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
BYD2_k127_8278203_4	644283.Micau_2023	5.38e-59	218.0	COG0496@1|root,COG0496@2|Bacteria,2IFAX@201174|Actinobacteria,4DGXT@85008|Micromonosporales	201174|Actinobacteria	S	Survival protein SurE	surE	-	3.1.3.5	ko:K03787	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01569,R01664,R01968,R02088,R02102,R02323,R02719,R03346	RC00017	ko00000,ko00001,ko01000	-	-	-	SurE
BYD2_k127_8278203_1	1313172.YM304_07740	1.457e-79	288.0	COG5002@1|root,COG5002@2|Bacteria,2GJY7@201174|Actinobacteria,4CMZJ@84992|Acidimicrobiia	84992|Acidimicrobiia	F	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K07768	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
BYD2_k127_8278203_0	1313172.YM304_07750	5.544e-99	333.0	COG0745@1|root,COG0745@2|Bacteria,2GKFS@201174|Actinobacteria,4CMYH@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K07776	ko02020,map02020	M00443	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_8278203_2	1313172.YM304_07790	7.361e-79	282.0	COG0477@1|root,COG2814@2|Bacteria,2GKRT@201174|Actinobacteria,4CN19@84992|Acidimicrobiia	84992|Acidimicrobiia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_8280699_0	1385520.N802_06510	0.0	1241.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2GN49@201174|Actinobacteria	201174|Actinobacteria	E	carboxypeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
BYD2_k127_8280699_5	1313172.YM304_31800	7.923e-35	145.0	COG2010@1|root,COG2010@2|Bacteria,2H614@201174|Actinobacteria	201174|Actinobacteria	C	Cytochrome c	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrome_CBB3
BYD2_k127_8280699_2	1209984.BN978_07455	1.355e-113	372.0	COG1024@1|root,COG1024@2|Bacteria,2GNZE@201174|Actinobacteria,235XP@1762|Mycobacteriaceae	201174|Actinobacteria	I	Belongs to the enoyl-CoA hydratase isomerase family	-	-	-	-	-	-	-	-	-	-	-	-	ECH_1
BYD2_k127_8280699_1	298654.FraEuI1c_5276	1.64e-205	647.0	COG2030@1|root,COG2030@2|Bacteria,2H7MB@201174|Actinobacteria,4ES36@85013|Frankiales	201174|Actinobacteria	I	N-terminal half of MaoC dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	MaoC_dehydrat_N
BYD2_k127_8280699_3	298654.FraEuI1c_5277	5.414e-99	349.0	COG1024@1|root,COG1024@2|Bacteria,2I2PC@201174|Actinobacteria,4EVCX@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase/isomerase	-	-	5.3.3.18	ko:K15866	ko00360,ko01120,map00360,map01120	-	R09837,R09839	RC00004,RC00326,RC02689,RC03003	ko00000,ko00001,ko01000	-	-	-	ECH_1
BYD2_k127_8280699_4	298655.KI912266_gene5762	4.338e-65	243.0	COG1960@1|root,COG1960@2|Bacteria,2IBE0@201174|Actinobacteria	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_8292891_1	1313172.YM304_28560	4.787e-36	158.0	COG1216@1|root,COG1216@2|Bacteria,2GIUN@201174|Actinobacteria,4CN7G@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3
BYD2_k127_8292891_2	1313172.YM304_28540	2.087e-35	150.0	COG0526@1|root,COG0526@2|Bacteria,2H7FG@201174|Actinobacteria	201174|Actinobacteria	CO	COG0526, thiol-disulfide isomerase and thioredoxins	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8292891_0	1121877.JQKF01000001_gene1297	1.036e-197	625.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4CMRD@84992|Acidimicrobiia	84992|Acidimicrobiia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
BYD2_k127_8310804_2	981369.JQMJ01000001_gene6675	2.507e-24	120.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,2I2M2@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA,Hpt,Response_reg,dCache_1
BYD2_k127_8310804_0	292415.Tbd_1072	0.0	1030.0	COG2132@1|root,COG2132@2|Bacteria,1MU0J@1224|Proteobacteria,2VS7B@28216|Betaproteobacteria	28216|Betaproteobacteria	Q	Multicopper oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Cu-oxidase_2
BYD2_k127_8310804_1	1123023.JIAI01000001_gene7246	5.251e-54	192.0	COG2057@1|root,COG2057@2|Bacteria,2GMA1@201174|Actinobacteria,4DZRW@85010|Pseudonocardiales	201174|Actinobacteria	I	Coenzyme A transferase	catJ	-	-	-	-	-	-	-	-	-	-	-	CoA_trans
BYD2_k127_8326582_3	1229780.BN381_210114	1.692e-86	297.0	COG1273@1|root,COG1273@2|Bacteria,2GJMU@201174|Actinobacteria,3UXEG@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	Ku70/Ku80 beta-barrel domain	ku	GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050790,GO:0050896,GO:0051340,GO:0051351,GO:0051716,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363	-	ko:K10979	ko03450,map03450	-	-	-	ko00000,ko00001,ko03400	-	-	-	Ku
BYD2_k127_8326582_1	1229780.BN381_210115	1.112e-113	373.0	COG3285@1|root,COG3285@2|Bacteria,2GJPX@201174|Actinobacteria,3UXC8@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	L	DNA polymerase LigD polymerase domain	ligD	GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576	6.5.1.1,6.5.1.6,6.5.1.7	ko:K01971,ko:K10747	ko03030,ko03410,ko03420,ko03430,ko03450,map03030,map03410,map03420,map03430,map03450	-	R00381,R00382,R10822,R10823	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	DNA_ligase_A_C,DNA_ligase_A_M,LigD_N
BYD2_k127_8326582_5	591158.SSMG_00040	1.234e-75	263.0	COG2227@1|root,COG2227@2|Bacteria,2GM7A@201174|Actinobacteria	201174|Actinobacteria	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
BYD2_k127_8326582_9	287986.DV20_06110	1.312e-29	121.0	COG2329@1|root,COG2329@2|Bacteria,2IQTI@201174|Actinobacteria	201174|Actinobacteria	S	Antibiotic biosynthesis monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	ABM
BYD2_k127_8326582_11	1123023.JIAI01000001_gene7347	5.281e-08	63.0	COG5516@1|root,COG5516@2|Bacteria,2GP70@201174|Actinobacteria,4E614@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative stress-induced transcription regulator	-	-	-	-	-	-	-	-	-	-	-	-	ABATE,zf-CGNR
BYD2_k127_8326582_8	1194165.CAJF01000005_gene2273	2.828e-31	136.0	COG0010@1|root,COG0010@2|Bacteria	2|Bacteria	E	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	-	-	3.5.3.1,3.5.3.11	ko:K01476,ko:K01480	ko00220,ko00330,ko01100,ko01110,ko01130,ko01230,ko05146,map00220,map00330,map01100,map01110,map01130,map01230,map05146	M00029,M00133,M00134	R00551,R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
BYD2_k127_8326582_10	1463825.JNXC01000043_gene7448	6.566e-24	112.0	COG0644@1|root,COG0644@2|Bacteria,2GUA3@201174|Actinobacteria,4E5PR@85010|Pseudonocardiales	201174|Actinobacteria	C	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_8326582_2	298654.FraEuI1c_1863	1.069e-87	290.0	COG2764@1|root,COG2764@2|Bacteria	2|Bacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8326582_7	298654.FraEuI1c_1864	1.813e-43	178.0	COG0640@1|root,COG0640@2|Bacteria,2GS8K@201174|Actinobacteria	201174|Actinobacteria	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_8326582_4	298654.FraEuI1c_1865	1.445e-78	270.0	COG3832@1|root,COG3832@2|Bacteria	2|Bacteria	J	glyoxalase III activity	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_8326582_0	1120950.KB892742_gene3055	5.786e-124	419.0	COG1819@1|root,COG1819@2|Bacteria,2GJN7@201174|Actinobacteria,4DR7K@85009|Propionibacteriales	201174|Actinobacteria	CG	UDP-glucoronosyl and UDP-glucosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	UDPGT
BYD2_k127_8326582_6	1229780.BN381_30015	9.776e-46	182.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GKEF@201174|Actinobacteria,3UXHV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,PAS_4,SpoIIE
BYD2_k127_8326582_12	1123320.KB889664_gene1212	2.088e-07	55.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_8336488_20	1229780.BN381_110032	1.094e-29	127.0	COG0157@1|root,COG0157@2|Bacteria,2GV9P@201174|Actinobacteria,3UWIJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Quinolinate phosphoribosyl transferase, N-terminal domain	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	-	QRPTase_C,QRPTase_N
BYD2_k127_8336488_5	67373.JOBF01000012_gene3886	4.309e-102	340.0	COG4894@1|root,COG4894@2|Bacteria,2GMU8@201174|Actinobacteria	201174|Actinobacteria	S	Scramblase	-	-	-	-	-	-	-	-	-	-	-	-	DUF2510,Scramblase
BYD2_k127_8336488_1	1229780.BN381_110031	1.744e-175	566.0	COG0029@1|root,COG0029@2|Bacteria,2I2IJ@201174|Actinobacteria,3UW8F@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Fumarate reductase flavoprotein C-term	nadB	GO:0008150,GO:0040007	1.4.3.16,2.4.2.19	ko:K00278,ko:K00767	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481,R03348	RC00006,RC02566,RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1595	FAD_binding_2,Succ_DH_flav_C
BYD2_k127_8336488_18	1380390.JIAT01000016_gene5542	1.83e-39	168.0	COG0853@1|root,COG0853@2|Bacteria,2IHTC@201174|Actinobacteria,4CSPV@84995|Rubrobacteria	84995|Rubrobacteria	H	Aspartate decarboxylase	-	-	4.1.1.11	ko:K01579	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R00489	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Asp_decarbox
BYD2_k127_8336488_6	1382304.JNIL01000001_gene811	7.252e-88	310.0	COG0414@1|root,COG0414@2|Bacteria,1TP7A@1239|Firmicutes,4HAIQ@91061|Bacilli,2784W@186823|Alicyclobacillaceae	91061|Bacilli	H	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate	panC	GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605	6.3.2.1	ko:K01918	ko00410,ko00770,ko01100,ko01110,map00410,map00770,map01100,map01110	M00119	R02473	RC00096,RC00141	ko00000,ko00001,ko00002,ko01000	-	-	-	Pantoate_ligase
BYD2_k127_8336488_15	1229780.BN381_110029	6.177e-57	216.0	COG5495@1|root,COG5495@2|Bacteria,2HGVN@201174|Actinobacteria,3UXIN@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Domain of unknown function (DUF2520)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2520
BYD2_k127_8336488_17	1229780.BN381_110028	7.058e-44	170.0	COG0801@1|root,COG0801@2|Bacteria,2H3G6@201174|Actinobacteria,3UWU2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK)	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
BYD2_k127_8336488_21	1229780.BN381_110027	3.173e-29	121.0	COG1539@1|root,COG1539@2|Bacteria,2IHSW@201174|Actinobacteria,3UWX7@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folB	GO:0008150,GO:0040007	1.13.11.81,2.7.6.3,4.1.2.25,5.1.99.8	ko:K01633,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00840	R03503,R03504,R11037,R11073	RC00002,RC00017,RC00721,RC00943,RC01479,RC03333,RC03334	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB
BYD2_k127_8336488_12	1229780.BN381_110026	3.854e-64	224.0	2F3QB@1|root,33WH4@2|Bacteria,2H50W@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8336488_10	525909.Afer_1911	5.29e-76	265.0	COG0294@1|root,COG0294@2|Bacteria,2GJDQ@201174|Actinobacteria,4CNEH@84992|Acidimicrobiia	84992|Acidimicrobiia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	-	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
BYD2_k127_8336488_7	1229780.BN381_110024	7.711e-83	279.0	COG0302@1|root,COG0302@2|Bacteria,2GP2P@201174|Actinobacteria,3UWJV@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	H	GTP cyclohydrolase I	folE	GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv3609c	GTP_cyclohydroI
BYD2_k127_8336488_0	469371.Tbis_3447	4.35e-234	742.0	COG0465@1|root,COG0465@2|Bacteria,2GJ4Q@201174|Actinobacteria,4DZME@85010|Pseudonocardiales	201174|Actinobacteria	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019222,GO:0019538,GO:0030163,GO:0040007,GO:0042623,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
BYD2_k127_8336488_11	525909.Afer_1913	6.614e-67	233.0	COG0634@1|root,COG0634@2|Bacteria,2GMDZ@201174|Actinobacteria,4CNRA@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Phosphoribosyl transferase domain	-	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
BYD2_k127_8336488_8	1313172.YM304_37680	1.392e-81	283.0	COG0037@1|root,COG0037@2|Bacteria,2GJR4@201174|Actinobacteria,4CN76@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3
BYD2_k127_8336488_3	1229780.BN381_110020	1.276e-113	380.0	COG5282@1|root,COG5282@2|Bacteria,2GJ8E@201174|Actinobacteria,3UXC9@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	Pfam:Zinicin_2	-	-	-	-	-	-	-	-	-	-	-	-	Zincin_2
BYD2_k127_8336488_16	353496.LBU_1595	1.827e-56	207.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,4HCBG@91061|Bacilli,3F51J@33958|Lactobacillaceae	91061|Bacilli	M	Bacterial sugar transferase	rfbP	-	-	ko:K13012,ko:K19428	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf
BYD2_k127_8336488_22	525909.Afer_1917	1.051e-16	82.0	29XP9@1|root,30JEV@2|Bacteria,2HGER@201174|Actinobacteria,4CNCS@84992|Acidimicrobiia	84992|Acidimicrobiia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_8336488_9	525909.Afer_1918	1.034e-78	282.0	COG1595@1|root,COG1595@2|Bacteria,2GJ02@201174|Actinobacteria,4CMZF@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Sigma-70, region 4	sigR	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_8336488_4	1114959.SZMC14600_19579	1.7e-105	364.0	COG1306@1|root,COG1306@2|Bacteria,2GNVR@201174|Actinobacteria,4E1HI@85010|Pseudonocardiales	201174|Actinobacteria	S	Putative glycosyl hydrolase domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4015
BYD2_k127_8336488_2	351607.Acel_0084	1.931e-141	462.0	COG3642@1|root,COG3642@2|Bacteria,2GIX0@201174|Actinobacteria,4ERCM@85013|Frankiales	201174|Actinobacteria	T	Domain of unknown function (DUF4032)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4032,Kdo
BYD2_k127_8336488_13	1323361.JPOC01000015_gene3730	1.844e-61	214.0	COG0346@1|root,COG0346@2|Bacteria,2IG0S@201174|Actinobacteria,4G0ZN@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8336488_14	298655.KI912267_gene7635	2.044e-59	213.0	COG2207@1|root,COG2207@2|Bacteria,2IFDE@201174|Actinobacteria,4EVBN@85013|Frankiales	201174|Actinobacteria	K	PFAM helix-turn-helix- domain containing protein AraC type	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
BYD2_k127_8336488_19	479435.Kfla_6666	9.833e-30	120.0	COG1246@1|root,COG1246@2|Bacteria,2IGUU@201174|Actinobacteria	201174|Actinobacteria	E	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
BYD2_k127_8336488_23	1246474.ANBE01000033_gene2625	0.0004768	49.0	COG3832@1|root,COG3832@2|Bacteria,2IFJT@201174|Actinobacteria,4EQ7Y@85012|Streptosporangiales	201174|Actinobacteria	S	Polyketide cyclase / dehydrase and lipid transport	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
BYD2_k127_8426178_0	1121296.JONJ01000013_gene280	4.379e-72	273.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,21Y0N@1506553|Lachnoclostridium	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
BYD2_k127_8434731_0	1172188.KB911820_gene2633	0.0	1020.0	COG2132@1|root,COG2132@2|Bacteria,2GMJ4@201174|Actinobacteria,4FG4H@85021|Intrasporangiaceae	201174|Actinobacteria	Q	Multicopper oxidase	-	-	1.3.3.5	ko:K08100	ko00860,ko01110,map00860,map01110	-	R02394	RC01983	ko00000,ko00001,ko01000	-	-	-	Cu-oxidase,Cu-oxidase_2,Cu-oxidase_3
BYD2_k127_8438305_37	369723.Strop_2573	0.0004248	49.0	COG2823@1|root,COG2823@2|Bacteria,2IS5M@201174|Actinobacteria,4DF8P@85008|Micromonosporales	201174|Actinobacteria	S	BON domain	-	-	-	-	-	-	-	-	-	-	-	-	BON
BYD2_k127_8438305_18	1449976.KALB_4798	1.29e-66	238.0	COG2172@1|root,COG2172@2|Bacteria,2GKU6@201174|Actinobacteria,4E0A3@85010|Pseudonocardiales	201174|Actinobacteria	T	MEDS: MEthanogen/methylotroph, DcmR Sensory domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_2,MEDS
BYD2_k127_8438305_36	443255.SCLAV_4911	1.826e-10	66.0	COG2203@1|root,COG2208@1|root,COG3290@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,COG3290@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,PAS_4,PAS_8,SpoIIE,sCache_3_2
BYD2_k127_8438305_28	1343740.M271_38985	1.012e-30	136.0	COG2203@1|root,COG2208@1|root,COG2203@2|Bacteria,COG2208@2|Bacteria,2GK8P@201174|Actinobacteria	201174|Actinobacteria	T	protein phosphatase 2C domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GAF,GAF_2,HATPase_c_2,PAS,PAS_4,PAS_9,SpoIIE,sCache_3_2
BYD2_k127_8438305_27	1206743.BAGM01000080_gene4113	4.385e-36	151.0	COG2208@1|root,COG2208@2|Bacteria,2I4EN@201174|Actinobacteria,4FU6H@85025|Nocardiaceae	201174|Actinobacteria	KT	Stage II sporulation protein E (SpoIIE)	rsbX	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
BYD2_k127_8438305_26	1380356.JNIK01000021_gene4648	1.692e-37	161.0	COG1595@1|root,COG2172@1|root,COG1595@2|Bacteria,COG2172@2|Bacteria,2IKM9@201174|Actinobacteria,4EWC7@85013|Frankiales	201174|Actinobacteria	T	Histidine kinase-like ATPase domain	rsbT	-	2.7.11.1	ko:K17752	-	-	-	-	ko00000,ko01000,ko01001,ko03021	-	-	-	HATPase_c,HATPase_c_2
BYD2_k127_8438305_23	1123023.JIAI01000010_gene8692	1.803e-47	172.0	COG1366@1|root,COG1366@2|Bacteria,2IKVE@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbS	-	-	ko:K17762	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
BYD2_k127_8438305_6	469383.Cwoe_3437	7.901e-142	456.0	COG1366@1|root,COG1366@2|Bacteria,2HPYR@201174|Actinobacteria	201174|Actinobacteria	T	Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor)	rsbR	-	-	ko:K17763	-	-	-	-	ko00000,ko03021	-	-	-	RsbRD_N,STAS
BYD2_k127_8438305_7	196162.Noca_3636	7.725e-137	449.0	COG3173@1|root,COG3173@2|Bacteria,2GSTN@201174|Actinobacteria	201174|Actinobacteria	S	Aminoglycoside phosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_8438305_4	1415166.NONO_c55160	7.58e-174	551.0	2BYTM@1|root,2Z7KC@2|Bacteria,2GJ6K@201174|Actinobacteria,4FU8Z@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8438305_0	357808.RoseRS_3480	7.663e-230	741.0	COG1472@1|root,COG1472@2|Bacteria,2G639@200795|Chloroflexi,374XN@32061|Chloroflexia	32061|Chloroflexia	G	Belongs to the glycosyl hydrolase 3 family	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C,PA14
BYD2_k127_8438305_31	1172179.AUKV01000009_gene4532	6.255e-22	102.0	COG2846@1|root,COG2846@2|Bacteria,2HC8E@201174|Actinobacteria	201174|Actinobacteria	D	Hemerythrin HHE cation binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Hemerythrin
BYD2_k127_8438305_24	700508.D174_26480	6.615e-45	181.0	COG4923@1|root,COG4923@2|Bacteria,2IJP8@201174|Actinobacteria,238UV@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF429)	-	-	-	-	-	-	-	-	-	-	-	-	DUF429
BYD2_k127_8438305_21	1896.JOAU01000026_gene3366	1.558e-51	193.0	COG0483@1|root,COG0483@2|Bacteria,2HDIP@201174|Actinobacteria	201174|Actinobacteria	G	Inositol monophosphatase family	strO	-	3.1.3.15	ko:K05602	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Inositol_P
BYD2_k127_8438305_17	928724.SacglDRAFT_00071	5.365e-77	275.0	COG2850@1|root,COG2850@2|Bacteria,2GMR2@201174|Actinobacteria,4DYRP@85010|Pseudonocardiales	201174|Actinobacteria	S	Cupin superfamily protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_4
BYD2_k127_8438305_19	1146883.BLASA_2202	4.081e-56	209.0	COG4759@1|root,COG4759@2|Bacteria,2GRSQ@201174|Actinobacteria,4ESKP@85013|Frankiales	201174|Actinobacteria	O	Sucrase/ferredoxin-like	-	-	-	-	-	-	-	-	-	-	-	-	Suc_Fer-like
BYD2_k127_8438305_34	1380390.JIAT01000003_gene5425	6.837e-15	76.0	2CIG4@1|root,33C84@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8438305_11	1380390.JIAT01000003_gene5424	2.759e-97	327.0	28P5T@1|root,2ZC0N@2|Bacteria,2GP34@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8438305_30	1120936.KB907216_gene3717	1.568e-27	115.0	COG2388@1|root,COG2388@2|Bacteria,2GQNP@201174|Actinobacteria,4EKDK@85012|Streptosporangiales	201174|Actinobacteria	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
BYD2_k127_8438305_22	1048339.KB913029_gene778	3.774e-48	179.0	COG0622@1|root,COG0622@2|Bacteria,2IFVB@201174|Actinobacteria,4ESMG@85013|Frankiales	201174|Actinobacteria	S	Phosphoesterase	ysnB	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
BYD2_k127_8438305_3	263358.VAB18032_11180	1.268e-182	583.0	COG4222@1|root,COG4222@2|Bacteria,2GJN8@201174|Actinobacteria,4DHG7@85008|Micromonosporales	201174|Actinobacteria	S	Endonuclease/Exonuclease/phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
BYD2_k127_8438305_8	585531.HMPREF0063_12013	5.05e-111	368.0	arCOG06481@1|root,2ZB4E@2|Bacteria,2I95D@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8438305_25	1313172.YM304_29340	1.567e-42	163.0	COG1051@1|root,COG1051@2|Bacteria	2|Bacteria	F	GDP-mannose mannosyl hydrolase activity	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF4743,NUDIX
BYD2_k127_8438305_12	1313172.YM304_41190	5.703e-95	330.0	COG2124@1|root,COG2124@2|Bacteria,2GJ8V@201174|Actinobacteria	201174|Actinobacteria	Q	cytochrome p450	-	-	-	-	-	-	-	-	-	-	-	-	p450
BYD2_k127_8438305_1	1229780.BN381_130370	1.591e-197	623.0	COG2159@1|root,COG2159@2|Bacteria,2HG7W@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_8438305_9	105425.BBPL01000009_gene1377	2.315e-110	365.0	COG4221@1|root,COG4221@2|Bacteria,2HA4H@201174|Actinobacteria,2NEYF@228398|Streptacidiphilus	201174|Actinobacteria	S	KR domain	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_8438305_10	298655.KI912267_gene7626	1.95e-103	346.0	COG4689@1|root,COG4689@2|Bacteria,2I8M2@201174|Actinobacteria	201174|Actinobacteria	Q	acetoacetate decarboxylase	-	-	4.1.1.4	ko:K01574	ko00072,ko00640,ko01100,map00072,map00640,map01100	M00088	R01366	RC00040	ko00000,ko00001,ko00002,ko01000	-	-	-	ADC
BYD2_k127_8438305_2	1229780.BN381_130373	3.492e-196	631.0	COG2159@1|root,COG2159@2|Bacteria,2GP2D@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
BYD2_k127_8438305_33	164757.Mjls_3234	2.662e-16	86.0	COG1309@1|root,COG1309@2|Bacteria,2GKR9@201174|Actinobacteria,236XG@1762|Mycobacteriaceae	201174|Actinobacteria	K	tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_8438305_13	1380393.JHVP01000005_gene3634	1.356e-92	337.0	COG0392@1|root,COG0392@2|Bacteria,2GMAV@201174|Actinobacteria,4EU4Q@85013|Frankiales	201174|Actinobacteria	S	Lysylphosphatidylglycerol synthase TM region	-	-	-	-	-	-	-	-	-	-	-	-	LPG_synthase_TM
BYD2_k127_8438305_29	365528.KB891102_gene4283	3.389e-30	123.0	COG2261@1|root,COG2261@2|Bacteria,2GS37@201174|Actinobacteria,4ETMQ@85013|Frankiales	201174|Actinobacteria	S	Transglycosylase associated protein	-	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
BYD2_k127_8438305_16	234267.Acid_6665	4.85e-78	284.0	COG1171@1|root,COG1171@2|Bacteria,3Y2RI@57723|Acidobacteria	57723|Acidobacteria	E	beta' subunit	-	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
BYD2_k127_8438305_20	390989.JOEG01000019_gene5888	2.925e-53	190.0	COG1720@1|root,COG1720@2|Bacteria,2IKKT@201174|Actinobacteria,4DE3M@85008|Micromonosporales	201174|Actinobacteria	S	Uncharacterised protein family UPF0066	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
BYD2_k127_8438305_14	208444.JNYY01000025_gene5964	3.399e-88	323.0	COG1672@1|root,COG2197@1|root,COG1672@2|Bacteria,COG2197@2|Bacteria,2I3QJ@201174|Actinobacteria,4EF66@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_8438305_15	711393.AYRX01000009_gene2394	7.979e-83	286.0	COG2962@1|root,COG2962@2|Bacteria,2GKCP@201174|Actinobacteria	201174|Actinobacteria	S	RarD protein	rarD	-	-	ko:K05786	-	-	-	-	ko00000,ko02000	2.A.7.7	-	-	EamA
BYD2_k127_8438305_5	1380390.JIAT01000015_gene5780	3.827e-157	526.0	COG1122@1|root,COG2138@1|root,COG1122@2|Bacteria,COG2138@2|Bacteria,2GJ0M@201174|Actinobacteria,4CPV4@84995|Rubrobacteria	84995|Rubrobacteria	P	CbiX	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,CbiX
BYD2_k127_8438305_35	365528.KB891219_gene1122	1.491e-11	72.0	COG0619@1|root,COG0619@2|Bacteria,2GKQ7@201174|Actinobacteria,4ESRU@85013|Frankiales	201174|Actinobacteria	P	TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
BYD2_k127_8439188_4	1121877.JQKF01000009_gene576	2.708e-45	168.0	COG1005@1|root,COG1005@2|Bacteria,2GIVY@201174|Actinobacteria,4CMTV@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone	-	-	1.6.5.3	ko:K00337	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	NADHdh
BYD2_k127_8439188_3	525909.Afer_0371	2.463e-86	299.0	COG1143@1|root,COG1143@2|Bacteria,2GJNU@201174|Actinobacteria,4CMPP@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	1.6.5.3	ko:K00338	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fer4
BYD2_k127_8439188_5	1313172.YM304_04150	2.048e-36	156.0	COG0839@1|root,COG0839@2|Bacteria,2GKRS@201174|Actinobacteria,4CN8Y@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NADH-ubiquinone/plastoquinone oxidoreductase chain 6	-	-	1.6.5.3	ko:K00339	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q3
BYD2_k127_8439188_6	525909.Afer_0373	1.365e-30	124.0	COG0713@1|root,COG0713@2|Bacteria,2IKV7@201174|Actinobacteria,4CN4N@84992|Acidimicrobiia	84992|Acidimicrobiia	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoK	-	1.6.5.3	ko:K00340	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q2
BYD2_k127_8439188_0	1313172.YM304_04170	1.062e-241	763.0	COG1009@1|root,COG1009@2|Bacteria,2GIT4@201174|Actinobacteria,4CMPU@84992|Acidimicrobiia	84992|Acidimicrobiia	CP	protein synonym multiple resistance and pH homeostasis protein A	-	-	1.6.5.3	ko:K00341	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M,Proton_antipo_N
BYD2_k127_8439188_2	671143.DAMO_2691	4.804e-135	472.0	COG1008@1|root,COG1008@2|Bacteria,2NNQ9@2323|unclassified Bacteria	2|Bacteria	C	NADH-quinone oxidoreductase, chain M	nuoM-1	-	1.6.5.3	ko:K00342	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Oxidored_q5_N,Proton_antipo_M
BYD2_k127_8439188_1	1229780.BN381_160014	3.306e-150	494.0	COG1007@1|root,COG1007@2|Bacteria,2GMGX@201174|Actinobacteria,3UWFY@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	nuoN	GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944	1.6.5.3	ko:K00343	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Proton_antipo_M
BYD2_k127_8439188_7	1415166.NONO_c17240	5.451e-10	71.0	COG1595@1|root,COG1595@2|Bacteria,2GJMX@201174|Actinobacteria,4FVYM@85025|Nocardiaceae	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_8485428_5	552811.Dehly_0857	6.416e-32	134.0	COG0697@1|root,COG0697@2|Bacteria,2G6XF@200795|Chloroflexi	200795|Chloroflexi	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
BYD2_k127_8485428_4	1380356.JNIK01000011_gene1782	7.484e-36	157.0	COG1595@1|root,COG1595@2|Bacteria,2GN5Y@201174|Actinobacteria,4ESZT@85013|Frankiales	201174|Actinobacteria	K	sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_8485428_0	1229780.BN381_100019	3.598e-171	542.0	COG0568@1|root,COG0568@2|Bacteria,2GK3Z@201174|Actinobacteria,3UWCE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	hrdD	-	-	ko:K03086,ko:K03087	ko02026,ko05111,map02026,map05111	-	-	-	ko00000,ko00001,ko03021	-	-	-	Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
BYD2_k127_8485428_2	1229780.BN381_30008	2.914e-94	331.0	COG0038@1|root,COG0038@2|Bacteria	2|Bacteria	P	chloride channel	-	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
BYD2_k127_8485428_3	525909.Afer_1925	1.603e-74	261.0	COG0560@1|root,COG0560@2|Bacteria,2GJVX@201174|Actinobacteria,4CN1K@84992|Acidimicrobiia	84992|Acidimicrobiia	E	haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD
BYD2_k127_8485428_7	1229780.BN381_150120	9.449e-18	94.0	2FKUI@1|root,34CEY@2|Bacteria,2HCF2@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8485428_1	1283299.AUKG01000002_gene4606	2.355e-98	337.0	COG4962@1|root,COG4962@2|Bacteria,2GKKJ@201174|Actinobacteria,4CR9H@84995|Rubrobacteria	84995|Rubrobacteria	U	Type II/IV secretion system protein	-	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
BYD2_k127_8485428_9	1122609.AUGT01000010_gene3810	1.356e-05	58.0	COG4965@1|root,COG4965@2|Bacteria,2I8NR@201174|Actinobacteria,4DRXI@85009|Propionibacteriales	201174|Actinobacteria	U	Type ii secretion system	-	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
BYD2_k127_8485428_8	33876.JNXY01000037_gene8039	1.229e-10	75.0	COG2064@1|root,COG2064@2|Bacteria,2GK7B@201174|Actinobacteria,4DGT4@85008|Micromonosporales	201174|Actinobacteria	NU	Type II secretion system (T2SS), protein F	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
BYD2_k127_8491090_2	204669.Acid345_0465	5.977e-313	987.0	COG0304@1|root,COG3321@1|root,COG4221@1|root,COG0304@2|Bacteria,COG3321@2|Bacteria,COG4221@2|Bacteria,3Y347@57723|Acidobacteria,2JHJH@204432|Acidobacteriia	204432|Acidobacteriia	Q	Ketoacyl-synthetase C-terminal extension	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,AMP-binding,AMP-binding_C,Acyl_transf_1,Condensation,KAsynt_C_assoc,KR,Ketoacyl-synt_C,Methyltransf_12,PP-binding,PS-DH,ketoacyl-synt
BYD2_k127_8491090_1	502025.Hoch_2100	0.0	1790.0	COG4770@1|root,COG4799@1|root,COG4770@2|Bacteria,COG4799@2|Bacteria,1P6RE@1224|Proteobacteria,43A2M@68525|delta/epsilon subdivisions,2X1XW@28221|Deltaproteobacteria,2YX2T@29|Myxococcales	28221|Deltaproteobacteria	I	Acetyl-CoA carboxylase, central region	-	-	-	-	-	-	-	-	-	-	-	-	ACC_central,Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,Carboxyl_trans
BYD2_k127_8491090_12	383372.Rcas_2880	6.808e-24	114.0	COG2091@1|root,COG2091@2|Bacteria,2G74T@200795|Chloroflexi,377PA@32061|Chloroflexia	32061|Chloroflexia	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
BYD2_k127_8491090_5	1151122.AQYD01000007_gene923	8.353e-144	469.0	COG5297@1|root,COG5297@2|Bacteria,2GK39@201174|Actinobacteria,4FNQX@85023|Microbacteriaceae	201174|Actinobacteria	G	Glycosyl hydrolases family 6	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	CBM_2,Glyco_hydro_6
BYD2_k127_8491090_8	926550.CLDAP_27080	2.022e-98	336.0	COG4992@1|root,COG4992@2|Bacteria,2G5TW@200795|Chloroflexi	2|Bacteria	E	TIGRFAM acetylornithine and succinylornithine aminotransferase	patA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0033094,GO:0034641,GO:0036094,GO:0042402,GO:0042802,GO:0043167,GO:0043168,GO:0044106,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:0097164,GO:1901363,GO:1901564,GO:1901565,GO:1901575	2.6.1.11,2.6.1.17,2.6.1.82	ko:K00821,ko:K05830,ko:K09251	ko00220,ko00300,ko00330,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map00330,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00031,M00763,M00845	R01155,R02283,R04475,R09778,R10932	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	iECIAI1_1343.ECIAI1_3220,iECSF_1327.ECSF_2916,iECs_1301.ECs3955,iZ_1308.Z4426	Aminotran_3
BYD2_k127_8491090_9	67267.JNXT01000038_gene3373	1.953e-51	199.0	2BWNB@1|root,32WFI@2|Bacteria,2IAXT@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8491090_16	710111.FraQA3DRAFT_2104	2.038e-05	57.0	2DGCV@1|root,2ZVG4@2|Bacteria,2IARW@201174|Actinobacteria	201174|Actinobacteria	S	Protein of unknown function (DUF3068)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3068
BYD2_k127_8491090_13	649743.HMPREF0972_00505	1.638e-11	71.0	COG1695@1|root,COG1695@2|Bacteria,2GNA1@201174|Actinobacteria,4D4PQ@85005|Actinomycetales	201174|Actinobacteria	K	transcriptional regulator PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_8491090_6	1120949.KB903301_gene6435	3.348e-131	424.0	COG1136@1|root,COG1136@2|Bacteria,2GK3I@201174|Actinobacteria,4DBJ7@85008|Micromonosporales	201174|Actinobacteria	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_8491090_4	1122611.KB903940_gene2049	2.052e-157	518.0	COG0577@1|root,COG0577@2|Bacteria,2I90E@201174|Actinobacteria,4EN3E@85012|Streptosporangiales	201174|Actinobacteria	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
BYD2_k127_8491090_10	1380390.JIAT01000010_gene4381	2.372e-42	160.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4CS3C@84995|Rubrobacteria	84995|Rubrobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
BYD2_k127_8491090_7	1380390.JIAT01000010_gene4380	6.453e-110	360.0	COG0596@1|root,COG0596@2|Bacteria,2GK79@201174|Actinobacteria,4CS3C@84995|Rubrobacteria	84995|Rubrobacteria	S	Epoxide hydrolase N terminus	-	-	-	-	-	-	-	-	-	-	-	-	EHN
BYD2_k127_8491090_11	936455.KI421499_gene3128	1.119e-39	160.0	COG0142@1|root,COG0142@2|Bacteria,1PACF@1224|Proteobacteria	1224|Proteobacteria	H	geranyltranstransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8491090_3	1454010.JEOE01000018_gene1173	1.586e-275	892.0	28MJW@1|root,2ZAW9@2|Bacteria,2H1U8@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8491090_0	930171.Asphe3_17310	0.0	1814.0	COG2885@1|root,COG2885@2|Bacteria,2IBAR@201174|Actinobacteria	201174|Actinobacteria	M	chlorophyll binding	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8491090_17	351607.Acel_1833	0.000458	48.0	COG1366@1|root,COG1366@2|Bacteria	2|Bacteria	T	antisigma factor binding	-	-	-	ko:K04749,ko:K06378	-	-	-	-	ko00000,ko03021	-	-	-	STAS,STAS_2
BYD2_k127_8491090_15	1246448.ANAZ01000003_gene5197	7.071e-09	57.0	2EQWD@1|root,33IG7@2|Bacteria,2GQNK@201174|Actinobacteria	201174|Actinobacteria	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_17
BYD2_k127_8491090_14	66869.JNXG01000004_gene2542	1.225e-09	62.0	COG0582@1|root,COG0582@2|Bacteria,2GISN@201174|Actinobacteria	201174|Actinobacteria	L	Belongs to the 'phage' integrase family	intA	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
BYD2_k127_8502125_5	1313172.YM304_16500	6.221e-106	349.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CMWG@84992|Acidimicrobiia	2|Bacteria	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	rimO	GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
BYD2_k127_8502125_12	1229780.BN381_80304	6.791e-45	177.0	COG0558@1|root,COG0558@2|Bacteria,2GK5D@201174|Actinobacteria,3UWWX@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	CDP-alcohol phosphatidyltransferase	pgsA	GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
BYD2_k127_8502125_4	1469245.JFBG01000054_gene2100	4.844e-150	484.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1RH2Y@1224|Proteobacteria,1T236@1236|Gammaproteobacteria	1236|Gammaproteobacteria	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
BYD2_k127_8502125_10	1298863.AUEP01000010_gene4480	1.991e-57	207.0	2CAJE@1|root,33XCP@2|Bacteria,2IMDF@201174|Actinobacteria,4DQZ9@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8502125_13	1246995.AFR_10835	7.082e-45	183.0	COG2940@1|root,COG2940@2|Bacteria,2GQAV@201174|Actinobacteria	201174|Actinobacteria	K	SET domain	-	-	-	ko:K07117	-	-	-	-	ko00000	-	-	-	SET
BYD2_k127_8502125_14	1464048.JNZS01000022_gene2484	3.85e-31	140.0	COG2315@1|root,COG2315@2|Bacteria,2ISFT@201174|Actinobacteria,4DEX8@85008|Micromonosporales	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_8502125_15	1313172.YM304_36780	4.653e-24	111.0	COG1514@1|root,COG1514@2|Bacteria	2|Bacteria	J	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester	ligT	-	3.1.4.58	ko:K01975	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	LigT_PEase
BYD2_k127_8502125_0	263358.VAB18032_12245	8.571e-304	951.0	COG0468@1|root,COG1372@1|root,COG0468@2|Bacteria,COG1372@2|Bacteria,2GJ4P@201174|Actinobacteria,4DAV3@85008|Micromonosporales	201174|Actinobacteria	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
BYD2_k127_8502125_1	1048339.KB913029_gene1969	3.181e-247	811.0	COG0410@1|root,COG0411@1|root,COG0410@2|Bacteria,COG0411@2|Bacteria,2H3P9@201174|Actinobacteria,4EXEI@85013|Frankiales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BCA_ABC_TP_C,BPD_transp_2
BYD2_k127_8502125_8	1229780.BN381_10244	4.467e-86	313.0	2FACV@1|root,342M7@2|Bacteria,2H6AW@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8502125_2	1313172.YM304_27040	9.673e-208	659.0	COG0621@1|root,COG0621@2|Bacteria,2GJEV@201174|Actinobacteria,4CMWG@84992|Acidimicrobiia	84992|Acidimicrobiia	J	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
BYD2_k127_8502125_16	1068978.AMETH_1545	3.199e-19	90.0	COG0454@1|root,COG0456@2|Bacteria,2IFF2@201174|Actinobacteria,4E3HI@85010|Pseudonocardiales	201174|Actinobacteria	K	PFAM Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_8502125_9	1229780.BN381_330033	1.823e-71	250.0	COG2120@1|root,COG2120@2|Bacteria,2IJJ0@201174|Actinobacteria	201174|Actinobacteria	S	GlcNAc-PI de-N-acetylase	-	-	-	-	-	-	-	-	-	-	-	-	PIG-L
BYD2_k127_8502125_17	269800.Tfu_1962	2.4e-16	89.0	COG0778@1|root,COG0778@2|Bacteria,2I5R3@201174|Actinobacteria,4EKY9@85012|Streptosporangiales	201174|Actinobacteria	C	Domain of unknown function (DUF1918)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1876,DUF1918
BYD2_k127_8502125_7	1313172.YM304_27020	2.602e-99	335.0	COG0324@1|root,COG0324@2|Bacteria,2GKFT@201174|Actinobacteria,4CN5X@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
BYD2_k127_8502125_11	1229780.BN381_80322	3.798e-50	193.0	COG0253@1|root,COG0253@2|Bacteria,2GKUD@201174|Actinobacteria,3UWMJ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
BYD2_k127_8502125_3	1313172.YM304_27000	1.424e-157	522.0	COG2262@1|root,COG2262@2|Bacteria,2GK55@201174|Actinobacteria,4CMWR@84992|Acidimicrobiia	84992|Acidimicrobiia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
BYD2_k127_8502125_6	1313172.YM304_26990	1.139e-102	340.0	COG0436@1|root,COG0436@2|Bacteria,2H440@201174|Actinobacteria,4CMXW@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2
BYD2_k127_8519461_9	1068980.ARVW01000001_gene1811	9.527e-33	134.0	COG3764@1|root,COG3764@2|Bacteria,2I91T@201174|Actinobacteria	201174|Actinobacteria	M	peptidase C60 sortase A and B	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
BYD2_k127_8519461_11	396014.BF93_15115	7.999e-30	121.0	arCOG05416@1|root,33310@2|Bacteria,2IQR4@201174|Actinobacteria,4FDZ3@85020|Dermabacteraceae	201174|Actinobacteria	S	lycopene cyclase	crtYc	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8519461_12	479435.Kfla_3860	2.462e-25	120.0	2E9MI@1|root,333U6@2|Bacteria,2IMX9@201174|Actinobacteria,4DS9I@85009|Propionibacteriales	201174|Actinobacteria	S	lycopene cyclase	crtYd	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8519461_10	1121877.JQKF01000013_gene278	3.445e-31	135.0	COG3000@1|root,COG3000@2|Bacteria,2HG86@201174|Actinobacteria,4CN57@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Fatty acid hydroxylase superfamily	-	-	1.14.15.24	ko:K15746	ko00906,ko01100,ko01110,map00906,map01100,map01110	M00372	R07530,R07558,R07559,R07561,R07562,R07568,R07569,R07570,R07572,R07851,R09747	RC00478,RC00704,RC02629	ko00000,ko00001,ko00002,ko01000	-	-	-	FA_hydroxylase
BYD2_k127_8519461_7	1385518.N798_05420	7.495e-49	182.0	2E9V0@1|root,3340V@2|Bacteria,2GVC5@201174|Actinobacteria	201174|Actinobacteria	S	carotenoid biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8519461_4	1385518.N798_05425	1.045e-87	302.0	COG1215@1|root,COG1215@2|Bacteria,2GJZI@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_tranf_2_3,Glyco_transf_21,Glycos_transf_2
BYD2_k127_8519461_2	1313172.YM304_37420	6.115e-100	355.0	COG1562@1|root,COG1562@2|Bacteria,2GJN2@201174|Actinobacteria,4CMYX@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Squalene/phytoene synthase	crtB	-	2.5.1.32,2.5.1.99	ko:K02291	ko00906,ko01062,ko01100,ko01110,map00906,map01062,map01100,map01110	M00097	R02065,R04218,R07270,R10177	RC00362,RC01101,RC02869	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	-	SQS_PSY
BYD2_k127_8519461_0	397278.JOJN01000012_gene2189	4.979e-191	610.0	COG1233@1|root,COG1233@2|Bacteria,2GJAV@201174|Actinobacteria,4DQ0T@85009|Propionibacteriales	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	crtI	-	1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31	ko:K10027	ko00906,ko01100,ko01110,map00906,map01100,map01110	-	R04787,R04798,R04800,R09691,R09692	RC01214,RC02088,RC02605	ko00000,ko00001,ko01000	-	-	-	Amino_oxidase
BYD2_k127_8519461_3	1043205.AFYF01000042_gene11	3.044e-99	349.0	COG0142@1|root,COG1443@1|root,COG0142@2|Bacteria,COG1443@2|Bacteria,2GM26@201174|Actinobacteria,4FJUV@85021|Intrasporangiaceae	201174|Actinobacteria	HI	Polyprenyl synthetase	idi	GO:0003674,GO:0003824,GO:0004452,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046490,GO:0071704,GO:0090407,GO:1901576	5.3.3.2	ko:K01823	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00095,M00096,M00364,M00365,M00366,M00367	R01123	RC00455	ko00000,ko00001,ko00002,ko01000	-	-	iNJ661.Rv1745c	NUDIX
BYD2_k127_8519461_1	479435.Kfla_0685	7.641e-161	523.0	COG0477@1|root,COG0477@2|Bacteria,2GIUM@201174|Actinobacteria,4DPWA@85009|Propionibacteriales	201174|Actinobacteria	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_8519461_6	882083.SacmaDRAFT_1980	4.434e-65	231.0	2DMQ5@1|root,32SZ1@2|Bacteria,2I3N2@201174|Actinobacteria	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_C,MDMPI_N
BYD2_k127_8519461_5	931627.MycrhDRAFT_2174	1.092e-79	280.0	COG2761@1|root,COG2761@2|Bacteria,2H7YD@201174|Actinobacteria,2359N@1762|Mycobacteriaceae	201174|Actinobacteria	Q	DSBA-like thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	DSBA
BYD2_k127_8519461_8	1449976.KALB_2026	3.705e-35	144.0	COG1011@1|root,COG1011@2|Bacteria	2|Bacteria	S	phosphatase activity	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like
BYD2_k127_8519935_4	543632.JOJL01000009_gene6011	1.019e-57	208.0	COG3459@1|root,COG3459@2|Bacteria,2IAZ0@201174|Actinobacteria,4DHXT@85008|Micromonosporales	201174|Actinobacteria	G	Putative carbohydrate binding domain	-	-	2.4.1.20	ko:K00702	ko00500,ko01100,map00500,map01100	-	R00952	RC00049	ko00000,ko00001,ko01000	-	GT36	-	Glyco_hydro_36,Glyco_transf_36
BYD2_k127_8519935_1	1048339.KB913029_gene1479	2.767e-182	584.0	COG2986@1|root,COG2986@2|Bacteria,2GJZW@201174|Actinobacteria,4ES63@85013|Frankiales	201174|Actinobacteria	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
BYD2_k127_8519935_0	1120936.KB907216_gene3780	1.183e-269	845.0	COG2987@1|root,COG2987@2|Bacteria,2GP10@201174|Actinobacteria,4EFM1@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
BYD2_k127_8519935_3	1463845.JOIG01000009_gene2866	1.208e-115	408.0	COG0402@1|root,COG0402@2|Bacteria,2GZ2Q@201174|Actinobacteria	201174|Actinobacteria	F	deiminase	hutF	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
BYD2_k127_8519935_2	414684.RC1_3234	8.337e-130	444.0	COG1228@1|root,COG1228@2|Bacteria,1MUYR@1224|Proteobacteria,2TSA1@28211|Alphaproteobacteria,2JR3Q@204441|Rhodospirillales	204441|Rhodospirillales	Q	imidazolonepropionase activity	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
BYD2_k127_8519935_5	710421.Mycch_0816	7.826e-18	89.0	COG0596@1|root,COG0596@2|Bacteria,2GY3A@201174|Actinobacteria,236DE@1762|Mycobacteriaceae	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_8530752_6	1298863.AUEP01000008_gene1150	5.857e-121	393.0	COG1960@1|root,COG1960@2|Bacteria,2GM1Q@201174|Actinobacteria,4DN00@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, middle domain	fadE30	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_8530752_2	1120950.KB892782_gene276	3.723e-155	515.0	COG0436@1|root,COG0436@2|Bacteria,2GJ7R@201174|Actinobacteria,4DN5T@85009|Propionibacteriales	201174|Actinobacteria	E	Cys/Met metabolism PLP-dependent enzyme	dapC	-	2.6.1.1,2.6.1.17	ko:K00812,ko:K10907,ko:K14267	ko00220,ko00250,ko00270,ko00300,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00300,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01120,map01130,map01210,map01230	M00016	R00355,R00694,R00734,R00896,R02433,R02619,R04475,R05052	RC00006	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
BYD2_k127_8530752_7	1313172.YM304_02550	5.441e-104	347.0	COG0388@1|root,COG0388@2|Bacteria,2GMQA@201174|Actinobacteria	201174|Actinobacteria	E	Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
BYD2_k127_8530752_0	1313172.YM304_02620	2.882e-211	682.0	COG1132@1|root,COG1132@2|Bacteria,2GITR@201174|Actinobacteria,4CMW8@84992|Acidimicrobiia	84992|Acidimicrobiia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
BYD2_k127_8530752_5	350054.Mflv_5093	3.846e-133	427.0	COG0648@1|root,COG0648@2|Bacteria,2GJJQ@201174|Actinobacteria,234Y8@1762|Mycobacteriaceae	201174|Actinobacteria	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
BYD2_k127_8530752_10	330084.JNYZ01000004_gene567	1.15e-35	137.0	COG1937@1|root,COG1937@2|Bacteria,2IQAC@201174|Actinobacteria,4E5MK@85010|Pseudonocardiales	201174|Actinobacteria	S	PFAM Uncharacterised BCR, COG1937	csoR	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
BYD2_k127_8530752_1	1120949.KB903294_gene3987	4.374e-165	527.0	COG0176@1|root,COG0176@2|Bacteria,2GMF9@201174|Actinobacteria,4D9UT@85008|Micromonosporales	201174|Actinobacteria	G	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
BYD2_k127_8530752_8	1229780.BN381_70131	5.26e-49	181.0	COG2346@1|root,COG2346@2|Bacteria,2IJM0@201174|Actinobacteria	201174|Actinobacteria	S	COG2346, Truncated hemoglobins	-	-	-	ko:K06886	-	-	-	-	ko00000	-	-	-	-
BYD2_k127_8530752_11	1440053.JOEI01000033_gene4801	1.217e-13	83.0	COG3189@1|root,COG3189@2|Bacteria,2IQC0@201174|Actinobacteria	201174|Actinobacteria	K	Protein of unknown function, DUF488	-	-	-	-	-	-	-	-	-	-	-	-	DUF488
BYD2_k127_8530752_12	7029.ACYPI006641-PA	6.767e-09	65.0	COG2227@1|root,KOG1270@2759|Eukaryota,39T8B@33154|Opisthokonta,3BE5R@33208|Metazoa,3CZ4I@33213|Bilateria,41YJT@6656|Arthropoda,3SKVV@50557|Insecta,3EAHB@33342|Paraneoptera	33208|Metazoa	H	O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway	COQ3	GO:0002119,GO:0002164,GO:0003674,GO:0003824,GO:0004395,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005975,GO:0006066,GO:0006071,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0007275,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008757,GO:0009058,GO:0009108,GO:0009791,GO:0009889,GO:0009987,GO:0010420,GO:0010565,GO:0010566,GO:0010795,GO:0016020,GO:0016740,GO:0016741,GO:0019222,GO:0019400,GO:0019751,GO:0019866,GO:0019898,GO:0031090,GO:0031312,GO:0031314,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032259,GO:0032501,GO:0032502,GO:0042180,GO:0042181,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0044595,GO:0044596,GO:0048856,GO:0050789,GO:0050794,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0061542,GO:0062012,GO:0065007,GO:0070013,GO:0071704,GO:1901576,GO:1901615,GO:1901661,GO:1901663	2.1.1.114,2.1.1.64	ko:K00591	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00128	R02175,R04711,R07235,R08771,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23
BYD2_k127_8530752_3	66874.JOFS01000005_gene3978	4.467e-155	507.0	COG0154@1|root,COG0154@2|Bacteria,2GKPZ@201174|Actinobacteria	201174|Actinobacteria	J	Belongs to the amidase family	-	-	3.5.1.4	ko:K01426	ko00330,ko00360,ko00380,ko00627,ko00643,ko01120,map00330,map00360,map00380,map00627,map00643,map01120	-	R02540,R03096,R03180,R03909,R05551,R05590	RC00010,RC00100,RC00950,RC01025	ko00000,ko00001,ko01000	-	-	-	Amidase
BYD2_k127_8530752_4	1177594.MIC448_530063	4.013e-138	452.0	2CA5R@1|root,2Z81H@2|Bacteria,2GM6V@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8530752_9	1121946.AUAX01000016_gene4651	9.925e-43	161.0	COG1695@1|root,COG1695@2|Bacteria,2IQSE@201174|Actinobacteria,4DEBZ@85008|Micromonosporales	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	ywzG	-	-	-	-	-	-	-	-	-	-	-	PadR
BYD2_k127_8533196_1	526225.Gobs_3749	3.929e-24	108.0	COG1669@1|root,COG1669@2|Bacteria	2|Bacteria	S	nucleotidyltransferase activity	-	-	-	ko:K07075	-	-	-	-	ko00000	-	-	-	NTP_transf_2
BYD2_k127_8533196_0	1313172.YM304_26380	4.181e-171	554.0	COG0277@1|root,COG0277@2|Bacteria,2GJ2T@201174|Actinobacteria,4CMS1@84992|Acidimicrobiia	84992|Acidimicrobiia	C	FAD linked oxidases, C-terminal domain	-	-	1.1.3.15	ko:K00104	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001,ko01000	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_8533196_2	688245.CtCNB1_0201	0.0009645	43.0	COG0277@1|root,COG0277@2|Bacteria,1MVYV@1224|Proteobacteria,2VHUQ@28216|Betaproteobacteria,4AAAA@80864|Comamonadaceae	28216|Betaproteobacteria	C	PFAM FAD linked oxidase domain protein	glcE	-	-	ko:K11472	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	FAD-oxidase_C,FAD_binding_4
BYD2_k127_8563446_0	1313172.YM304_24900	5.043e-241	773.0	COG0504@1|root,COG0504@2|Bacteria,2GJ13@201174|Actinobacteria,4CMQD@84992|Acidimicrobiia	84992|Acidimicrobiia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_synth_N,GATase
BYD2_k127_8563446_1	1229780.BN381_30019	8.803e-91	324.0	COG1062@1|root,COG1062@2|Bacteria,2GM8C@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	1.1.1.1,1.1.1.284	ko:K00121	ko00010,ko00071,ko00350,ko00625,ko00626,ko00680,ko00830,ko00980,ko00982,ko01100,ko01110,ko01120,ko01130,ko01200,ko01220,ko05204,map00010,map00071,map00350,map00625,map00626,map00680,map00830,map00980,map00982,map01100,map01110,map01120,map01130,map01200,map01220,map05204	-	R00623,R00754,R02124,R04880,R05233,R05234,R06917,R06927,R06983,R07105,R08281,R08306,R08310	RC00050,RC00087,RC00088,RC00099,RC00116,RC00649,RC01715,RC01734,RC02273	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_8563446_3	1464048.JNZS01000008_gene6095	2.069e-39	156.0	COG0542@1|root,COG0542@2|Bacteria,2GKKF@201174|Actinobacteria,4DA85@85008|Micromonosporales	201174|Actinobacteria	O	Clp amino terminal domain, pathogenicity island component	clpC2	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464	-	-	-	-	-	-	-	-	-	-	Clp_N
BYD2_k127_8563446_4	269800.Tfu_2028	2.426e-37	153.0	COG0472@1|root,COG0472@2|Bacteria,2HS8K@201174|Actinobacteria,4EG6C@85012|Streptosporangiales	201174|Actinobacteria	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8563446_2	446471.Xcel_0216	5.722e-44	172.0	2C76P@1|root,32RIH@2|Bacteria,2IFWF@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8563446_5	1211815.CBYP010000060_gene3026	1.498e-28	130.0	COG3119@1|root,COG3119@2|Bacteria,2H59R@201174|Actinobacteria,4EURD@85013|Frankiales	201174|Actinobacteria	P	arylsulfatase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8579297_1	1240349.ANGC01000016_gene774	2.967e-79	281.0	COG2124@1|root,COG2124@2|Bacteria,2GKCG@201174|Actinobacteria,4FZ1Q@85025|Nocardiaceae	201174|Actinobacteria	C	Belongs to the cytochrome P450 family	-	-	1.14.13.141	ko:K15981	ko00984,ko01120,map00984,map01120	-	R09859,R11357	RC01216,RC03368	ko00000,ko00001,ko00199,ko01000	-	-	-	p450
BYD2_k127_8579297_0	298655.KI912266_gene4193	2.37e-114	383.0	COG1012@1|root,COG1012@2|Bacteria,2GIWZ@201174|Actinobacteria	201174|Actinobacteria	C	Belongs to the aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
BYD2_k127_8585030_2	1229780.BN381_450068	5.827e-39	151.0	COG1595@1|root,COG1595@2|Bacteria,2GP9D@201174|Actinobacteria,3UWW2@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	ECF sigma factor	sigK	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_8585030_4	222534.KB893750_gene4397	2.271e-15	89.0	COG5343@1|root,COG5343@2|Bacteria,2I8NI@201174|Actinobacteria,4ETKR@85013|Frankiales	201174|Actinobacteria	S	Anti-sigma-K factor rskA	rskA	-	-	-	-	-	-	-	-	-	-	-	RskA,zf-HC2
BYD2_k127_8585030_0	644283.Micau_5428	2.274e-145	480.0	COG2041@1|root,COG2041@2|Bacteria,2GMG2@201174|Actinobacteria,4D8HC@85008|Micromonosporales	201174|Actinobacteria	S	Oxidoreductase molybdopterin binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mo-co_dimer,Oxidored_molyb
BYD2_k127_8585030_3	367299.JOEE01000001_gene1779	8.971e-34	141.0	COG2335@1|root,COG2335@2|Bacteria,2GJC2@201174|Actinobacteria,4FGIX@85021|Intrasporangiaceae	201174|Actinobacteria	M	Fasciclin	mpt	GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136	-	-	-	-	-	-	-	-	-	-	Fasciclin
BYD2_k127_8585030_1	164757.Mjls_1696	3.897e-92	311.0	COG0638@1|root,COG0638@2|Bacteria,2HIHG@201174|Actinobacteria,234TK@1762|Mycobacteriaceae	201174|Actinobacteria	O	20S proteasome	-	-	-	-	-	-	-	-	-	-	-	-	Proteasome
BYD2_k127_8585030_5	1229780.BN381_150047	8.923e-13	68.0	COG0346@1|root,COG0346@2|Bacteria,2IIPR@201174|Actinobacteria,3UWVQ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	Glyoxalase-like domain	mce	-	5.1.99.1	ko:K05606	ko00280,ko00630,ko00640,ko00720,ko01100,ko01120,ko01200,map00280,map00630,map00640,map00720,map01100,map01120,map01200	M00373,M00375,M00376,M00741	R02765,R09979	RC00780,RC02739	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyoxalase_4
BYD2_k127_8585470_8	1150864.MILUP08_44858	2.613e-08	56.0	COG0491@1|root,COG0491@2|Bacteria	2|Bacteria	GM	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid	-	-	3.1.1.81	ko:K13075	ko02024,map02024	-	R08970	RC00713	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
BYD2_k127_8585470_4	1120949.KB903294_gene4301	5.934e-89	299.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C,TetR_N
BYD2_k127_8585470_1	1229780.BN381_250066	6.512e-197	629.0	COG1960@1|root,COG1960@2|Bacteria,2GJDT@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_8585470_0	710685.MycrhN_1047	6.188e-230	735.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria,232ME@1762|Mycobacteriaceae	201174|Actinobacteria	IQ	COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II	fadD13	GO:0003674,GO:0003824,GO:0004321,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009268,GO:0009628,GO:0010447,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0030312,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051704,GO:0071944	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BYD2_k127_8585470_5	471852.Tcur_1307	3.014e-47	180.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_8585470_2	58123.JOFJ01000009_gene1054	3.679e-160	518.0	COG1233@1|root,COG3349@1|root,COG1233@2|Bacteria,COG3349@2|Bacteria,2IAFV@201174|Actinobacteria	201174|Actinobacteria	Q	Flavin containing amine oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Amino_oxidase
BYD2_k127_8585470_3	710421.Mycch_3320	2.014e-127	417.0	COG3320@1|root,COG3320@2|Bacteria,2GKZY@201174|Actinobacteria,236ZW@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Male sterility protein	acrA1_1	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_4
BYD2_k127_8585470_6	700508.D174_25040	8.283e-35	134.0	COG1063@1|root,COG1063@2|Bacteria,2GKC7@201174|Actinobacteria,233C1@1762|Mycobacteriaceae	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_8592021_3	1828.JOKB01000041_gene3974	3.447e-49	178.0	COG1018@1|root,COG1018@2|Bacteria,2HHWF@201174|Actinobacteria,4G1BC@85025|Nocardiaceae	201174|Actinobacteria	C	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_6,NAD_binding_1
BYD2_k127_8592021_1	479434.Sthe_0341	2.583e-96	320.0	COG2041@1|root,COG2041@2|Bacteria,2G6ES@200795|Chloroflexi	200795|Chloroflexi	S	PFAM oxidoreductase, molybdopterin binding	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_molyb
BYD2_k127_8592021_4	882083.SacmaDRAFT_2363	1.102e-33	136.0	COG4828@1|root,COG4828@2|Bacteria,2IQJ3@201174|Actinobacteria,4E5QJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
BYD2_k127_8592021_6	298654.FraEuI1c_0868	3.29e-24	113.0	COG1576@1|root,COG1576@2|Bacteria,2IGAN@201174|Actinobacteria,4ET6E@85013|Frankiales	201174|Actinobacteria	J	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MDMPI_N
BYD2_k127_8592021_5	1032480.MLP_45300	1.374e-29	128.0	COG0640@1|root,COG0640@2|Bacteria,2IR66@201174|Actinobacteria,4DV8G@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5
BYD2_k127_8592021_2	1121019.AUMN01000021_gene1282	1.985e-50	188.0	COG3832@1|root,COG3832@2|Bacteria,2GSCI@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	AHSA1
BYD2_k127_8592021_0	1123024.AUII01000010_gene684	1.594e-189	600.0	COG0477@1|root,COG2814@2|Bacteria,2GNBV@201174|Actinobacteria,4E2F7@85010|Pseudonocardiales	201174|Actinobacteria	EGP	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
BYD2_k127_8615957_3	994479.GL877881_gene6542	2.442e-157	509.0	COG0491@1|root,COG2897@1|root,COG0491@2|Bacteria,COG2897@2|Bacteria,2GN50@201174|Actinobacteria,4E0KC@85010|Pseudonocardiales	201174|Actinobacteria	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Rhodanese
BYD2_k127_8615957_12	258533.BN977_04341	3.032e-66	234.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,23999@1762|Mycobacteriaceae	201174|Actinobacteria	K	Rhodanese-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
BYD2_k127_8615957_20	1449353.JQMQ01000005_gene1822	5.81e-28	123.0	COG0789@1|root,COG0789@2|Bacteria,2I8PU@201174|Actinobacteria,2NH31@228398|Streptacidiphilus	201174|Actinobacteria	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
BYD2_k127_8615957_14	675635.Psed_4350	2.164e-60	225.0	COG3173@1|root,COG3173@2|Bacteria	2|Bacteria	S	very-long-chain-acyl-CoA dehydrogenase activity	amgP	-	-	-	-	-	-	-	-	-	-	-	APH
BYD2_k127_8615957_21	390989.JOEG01000004_gene3892	1.778e-26	115.0	COG0346@1|root,COG0346@2|Bacteria,2ISPK@201174|Actinobacteria,4DJQG@85008|Micromonosporales	201174|Actinobacteria	E	lactoylglutathione lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8615957_8	408672.NBCG_02422	3.451e-74	256.0	COG0607@1|root,COG0640@1|root,COG0607@2|Bacteria,COG0640@2|Bacteria,2I98A@201174|Actinobacteria,4DQM0@85009|Propionibacteriales	201174|Actinobacteria	K	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20,HTH_5,Rhodanese
BYD2_k127_8615957_15	1122138.AQUZ01000019_gene8182	1.358e-53	196.0	COG1595@1|root,COG1595@2|Bacteria,2H45C@201174|Actinobacteria	201174|Actinobacteria	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_8615957_25	743718.Isova_0560	9.39e-16	86.0	2DGEZ@1|root,2ZVQ5@2|Bacteria,2GYKS@201174|Actinobacteria	201174|Actinobacteria	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
BYD2_k127_8615957_7	1122138.AQUZ01000019_gene8184	7.316e-78	272.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4DNPK@85009|Propionibacteriales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.137	ko:K07755	-	-	-	-	ko00000,ko01000	-	-	-	Methyltransf_31
BYD2_k127_8615957_11	1123024.AUII01000010_gene681	5.601e-69	249.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
BYD2_k127_8615957_9	748247.AZKH_0540	8.736e-72	253.0	COG5588@1|root,COG5588@2|Bacteria,1MWK3@1224|Proteobacteria,2VMAI@28216|Betaproteobacteria	28216|Betaproteobacteria	S	Protein of unknown function (DUF1326)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1326
BYD2_k127_8615957_10	266117.Rxyl_0427	3.374e-70	251.0	COG5486@1|root,COG5486@2|Bacteria,2IAYZ@201174|Actinobacteria,4CTJ6@84995|Rubrobacteria	84995|Rubrobacteria	S	Predicted metal-binding integral membrane protein (DUF2182)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2182
BYD2_k127_8615957_26	2045.KR76_23825	4.961e-12	69.0	COG1846@1|root,COG1846@2|Bacteria,2I08I@201174|Actinobacteria,4DW8B@85009|Propionibacteriales	201174|Actinobacteria	K	Transcriptional regulator, MarR family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8615957_16	680646.RMDY18_18820	4.566e-45	177.0	COG1404@1|root,COG1404@2|Bacteria,2GK3D@201174|Actinobacteria,1W8TR@1268|Micrococcaceae	201174|Actinobacteria	O	Subtilase family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_5,PA,Peptidase_S8,SLH,fn3_5
BYD2_k127_8615957_4	66874.JOFS01000035_gene607	9.393e-112	376.0	COG4292@1|root,COG4292@2|Bacteria,2IC48@201174|Actinobacteria	201174|Actinobacteria	S	Bacterial low temperature requirement A protein (LtrA)	-	-	-	-	-	-	-	-	-	-	-	-	LtrA
BYD2_k127_8615957_27	408672.NBCG_03039	1.535e-10	72.0	COG1309@1|root,COG1309@2|Bacteria,2GN0W@201174|Actinobacteria,4DWR9@85009|Propionibacteriales	201174|Actinobacteria	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
BYD2_k127_8615957_18	1229780.BN381_80274	1.66e-36	150.0	COG1396@1|root,COG1396@2|Bacteria,2I569@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
BYD2_k127_8615957_0	1429046.RR21198_1985	0.0	1365.0	COG3119@1|root,COG3119@2|Bacteria,2GJ8H@201174|Actinobacteria,4FURR@85025|Nocardiaceae	201174|Actinobacteria	P	Arylsulfatase	-	-	3.1.6.1	ko:K01130	ko00140,ko00600,map00140,map00600	-	R03980,R04856	RC00128,RC00231	ko00000,ko00001,ko01000	-	-	-	Sulfatase
BYD2_k127_8615957_19	1158050.KB895452_gene636	5.159e-34	139.0	COG1309@1|root,COG1309@2|Bacteria,2IJP2@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_11,TetR_N
BYD2_k127_8615957_5	710687.KI912270_gene5999	9.09e-98	328.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria,23B3U@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Methyltransferase domain	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
BYD2_k127_8615957_28	298653.Franean1_6284	1.141e-09	67.0	COG1357@1|root,COG1357@2|Bacteria,2IB55@201174|Actinobacteria	201174|Actinobacteria	S	PFAM pentapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
BYD2_k127_8615957_24	1894.JOER01000002_gene3530	1.546e-22	103.0	COG0745@1|root,COG0745@2|Bacteria,2GIZB@201174|Actinobacteria	201174|Actinobacteria	T	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	ko:K07669,ko:K07672	ko02020,map02020	M00460,M00463	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_8615957_13	929712.KI912613_gene1358	5.751e-61	228.0	COG5002@1|root,COG5002@2|Bacteria,2I2WW@201174|Actinobacteria	201174|Actinobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
BYD2_k127_8615957_6	1120948.KB903243_gene2684	1.224e-95	321.0	COG0745@1|root,COG0745@2|Bacteria,2GMG9@201174|Actinobacteria,4E1D6@85010|Pseudonocardiales	201174|Actinobacteria	T	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
BYD2_k127_8615957_1	485913.Krac_5846	6.739e-213	672.0	COG0076@1|root,COG0076@2|Bacteria,2G76V@200795|Chloroflexi	200795|Chloroflexi	H	COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein	-	-	4.1.2.27	ko:K01634	ko00600,ko01100,ko04071,map00600,map01100,map04071	M00100	R02464,R06516	RC00264,RC00721,RC01266	ko00000,ko00001,ko00002,ko01000	-	-	-	Pyridoxal_deC
BYD2_k127_8615957_17	1380390.JIAT01000011_gene2363	5.792e-39	157.0	2CA7I@1|root,30E5G@2|Bacteria,2IJ78@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8615957_2	1449347.JQLN01000005_gene4843	6.786e-161	532.0	COG0038@1|root,COG0038@2|Bacteria,2GJHP@201174|Actinobacteria,2M3DH@2063|Kitasatospora	201174|Actinobacteria	P	Voltage gated chloride channel	-	-	-	-	-	-	-	-	-	-	-	-	Voltage_CLC
BYD2_k127_8646529_0	1121272.KB903259_gene6550	2.172e-175	555.0	COG1064@1|root,COG1064@2|Bacteria,2GKNW@201174|Actinobacteria,4D97N@85008|Micromonosporales	201174|Actinobacteria	S	Zinc-binding dehydrogenase	-	-	-	ko:K18382	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_8646529_14	1077144.AGFF01000007_gene1799	5.087e-86	308.0	COG0451@1|root,COG0451@2|Bacteria,2I2UT@201174|Actinobacteria	201174|Actinobacteria	M	epimerase dehydratase	galE1	GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944	4.2.1.46,5.1.3.2	ko:K01710,ko:K01784	ko00052,ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00052,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00362,M00632,M00793	R00291,R02984,R06513	RC00289,RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
BYD2_k127_8646529_9	1229780.BN381_10183	4.463e-113	376.0	COG1208@1|root,COG1208@2|Bacteria,2GKTE@201174|Actinobacteria,3UXFW@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	JM	Nucleotidyl transferase	manC	-	2.7.7.13	ko:K00966	ko00051,ko00520,ko01100,ko01110,map00051,map00520,map01100,map01110	M00114,M00361,M00362	R00885	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
BYD2_k127_8646529_4	1229780.BN381_10181	1.134e-141	461.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	wcaI	-	-	ko:K03208	-	-	-	-	ko00000	-	GT4	-	Glyco_trans_1_4,Glyco_trans_4_4,Glycos_transf_1
BYD2_k127_8646529_10	365528.KB891219_gene1134	1.604e-102	351.0	COG0438@1|root,COG0438@2|Bacteria,2IJX1@201174|Actinobacteria,4EV7B@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
BYD2_k127_8646529_11	351607.Acel_0448	6.388e-99	340.0	COG0438@1|root,COG0438@2|Bacteria,2GMEW@201174|Actinobacteria,4EU38@85013|Frankiales	201174|Actinobacteria	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_8646529_8	1229780.BN381_10178	3.199e-129	434.0	COG0451@1|root,COG0451@2|Bacteria,2GP0W@201174|Actinobacteria,3UX7T@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	GM	RmlD substrate binding domain	fcl	-	1.1.1.271	ko:K02377	ko00051,ko00520,ko01100,map00051,map00520,map01100	-	R05692	RC01014	ko00000,ko00001,ko01000	-	-	-	Epimerase
BYD2_k127_8646529_16	1120950.KB892761_gene5824	2.759e-80	285.0	2BVX8@1|root,30QZQ@2|Bacteria,2GZ2G@201174|Actinobacteria,4DUP1@85009|Propionibacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8646529_6	926550.CLDAP_15490	5.321e-134	440.0	COG0451@1|root,COG0451@2|Bacteria,2G64F@200795|Chloroflexi	200795|Chloroflexi	M	PFAM NAD-dependent epimerase dehydratase	-	-	4.1.1.35,4.2.1.46	ko:K01710,ko:K08678	ko00520,ko00521,ko00523,ko00525,ko01055,ko01100,ko01130,map00520,map00521,map00523,map00525,map01055,map01100,map01130	M00361,M00793	R01384,R06513	RC00402,RC00508	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
BYD2_k127_8646529_2	1229780.BN381_10176	3.14e-155	502.0	COG1004@1|root,COG1004@2|Bacteria,2GJQB@201174|Actinobacteria,3UW6R@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
BYD2_k127_8646529_17	479433.Caci_5663	3.426e-72	259.0	COG0300@1|root,COG0300@2|Bacteria,2GNPI@201174|Actinobacteria	201174|Actinobacteria	S	Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases)	phbB	-	1.1.1.333	ko:K16652	-	-	-	-	ko00000,ko01000	-	-	-	adh_short
BYD2_k127_8646529_13	1120950.KB892742_gene3046	5.106e-88	303.0	COG0382@1|root,COG0382@2|Bacteria,2GJ6P@201174|Actinobacteria,4DQNM@85009|Propionibacteriales	201174|Actinobacteria	H	UbiA prenyltransferase family	-	-	2.4.2.45	ko:K14136	-	-	R10095	RC00005	ko00000,ko01000,ko01006	-	-	-	UbiA
BYD2_k127_8646529_3	436229.JOEH01000041_gene6328	9.491e-148	492.0	COG0277@1|root,COG0277@2|Bacteria,2HH8C@201174|Actinobacteria,2NGT9@228398|Streptacidiphilus	201174|Actinobacteria	C	D-arabinono-1,4-lactone oxidase	-	-	-	-	-	-	-	-	-	-	-	-	ALO,FAD_binding_4
BYD2_k127_8646529_12	1229780.BN381_10136	7.506e-95	320.0	COG1091@1|root,COG1091@2|Bacteria,2GNY8@201174|Actinobacteria,3UWQ1@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rmlD	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008831,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019305,GO:0019438,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576	1.1.1.133	ko:K00067	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777	RC00182	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
BYD2_k127_8646529_5	1229780.BN381_10113	1.148e-138	449.0	COG1088@1|root,COG1088@2|Bacteria,2GNDU@201174|Actinobacteria,3UWG6@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	M	Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily	strE	GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
BYD2_k127_8646529_21	543632.JOJL01000011_gene6705	7.029e-13	81.0	COG1520@1|root,COG1520@2|Bacteria	2|Bacteria	S	amino acid activation for nonribosomal peptide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	PQQ_2,PQQ_3
BYD2_k127_8646529_1	479435.Kfla_1418	3.436e-162	521.0	COG1960@1|root,COG1960@2|Bacteria,2GMEM@201174|Actinobacteria,4DNK5@85009|Propionibacteriales	201174|Actinobacteria	I	Acyl-CoA dehydrogenase, C-terminal domain	fadE19	GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681	1.3.8.1,1.3.99.12	ko:K00248,ko:K11410	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_8646529_7	1449355.JQNR01000005_gene5215	3.45e-131	428.0	COG0147@1|root,COG0147@2|Bacteria,2GN7D@201174|Actinobacteria	201174|Actinobacteria	EH	PFAM chorismate	pabB	-	2.6.1.85,4.1.3.38	ko:K01665,ko:K03342	ko00790,map00790	-	R01716,R05553	RC00010,RC01418,RC01843,RC02148	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_4,Chorismate_bind
BYD2_k127_8646529_15	1120936.KB907221_gene2122	8.535e-85	295.0	COG0115@1|root,COG0115@2|Bacteria,2GN5Z@201174|Actinobacteria,4EH1U@85012|Streptosporangiales	201174|Actinobacteria	EH	Amino-transferase class IV	-	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
BYD2_k127_8646529_19	1451261.AS96_06070	5.082e-31	133.0	2EGCD@1|root,33A46@2|Bacteria,2HST0@201174|Actinobacteria,4FQBR@85023|Microbacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Septum_form
BYD2_k127_8646529_18	1449353.JQMQ01000005_gene3827	2.97e-44	171.0	COG0340@1|root,COG0340@2|Bacteria,2GN8Q@201174|Actinobacteria,2NGJ6@228398|Streptacidiphilus	201174|Actinobacteria	H	Biotin protein ligase C terminal domain	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB
BYD2_k127_8735298_8	882083.SacmaDRAFT_2716	3.431e-59	229.0	COG0715@1|root,COG0715@2|Bacteria,2HH8J@201174|Actinobacteria,4E9TU@85010|Pseudonocardiales	201174|Actinobacteria	P	NMT1-like family	ssuA_3	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1
BYD2_k127_8735298_4	882083.SacmaDRAFT_2713	1.365e-93	329.0	COG1116@1|root,COG1116@2|Bacteria,2GM73@201174|Actinobacteria,4E9GC@85010|Pseudonocardiales	201174|Actinobacteria	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
BYD2_k127_8735298_5	500153.JOEK01000021_gene23	3.677e-71	262.0	COG0600@1|root,COG0600@2|Bacteria,2GKKZ@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
BYD2_k127_8735298_7	500153.JOEK01000021_gene22	9.924e-61	240.0	COG0600@1|root,COG0600@2|Bacteria,2GP2J@201174|Actinobacteria	201174|Actinobacteria	P	ABC-type nitrate sulfonate bicarbonate transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
BYD2_k127_8735298_0	479433.Caci_4902	1.439e-187	598.0	COG0318@1|root,COG0318@2|Bacteria,2GIUC@201174|Actinobacteria	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	-	ko:K00666	-	-	-	-	ko00000,ko01000,ko01004	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_8735298_1	47716.JOFH01000004_gene995	5.991e-127	435.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria	201174|Actinobacteria	S	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
BYD2_k127_8735298_2	1122611.KB903985_gene3626	1.914e-113	409.0	COG2828@1|root,COG2828@2|Bacteria,2GJF3@201174|Actinobacteria,4EMKF@85012|Streptosporangiales	201174|Actinobacteria	S	PrpF protein	-	-	5.3.2.8	ko:K16514	ko00362,ko01120,map00362,map01120	-	R07839	RC02426	ko00000,ko00001,ko01000	-	-	-	PrpF
BYD2_k127_8735298_3	1218084.BBJK01000073_gene5137	2.42e-103	359.0	COG3618@1|root,COG3618@2|Bacteria,1N2QM@1224|Proteobacteria,2VIDM@28216|Betaproteobacteria,1K42J@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Amidohydrolase	-	-	3.1.1.57	ko:K10221	ko00362,ko00627,ko01120,map00362,map00627,map01120	-	R04277	RC03110	ko00000,ko00001,ko01000	-	-	-	Amidohydro_2
BYD2_k127_8735298_6	452652.KSE_07800	4.686e-66	242.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria,2M24B@2063|Kitasatospora	452652.KSE_07800|-	KLT	Protein tyrosine kinase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8752545_4	1313172.YM304_24400	1.062e-86	292.0	COG2188@1|root,COG2188@2|Bacteria,2HF8W@201174|Actinobacteria,4CN6C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	UTRA	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
BYD2_k127_8752545_0	1229780.BN381_430007	0.0	1092.0	COG1048@1|root,COG1048@2|Bacteria,2GJD5@201174|Actinobacteria,3UW9M@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate	acnA	GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
BYD2_k127_8752545_11	73044.JNXP01000005_gene360	5.255e-34	151.0	COG0346@1|root,COG0346@2|Bacteria,2II17@201174|Actinobacteria	201174|Actinobacteria	E	glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8752545_12	1283299.AUKG01000002_gene3725	1.01e-29	137.0	COG5001@1|root,COG5001@2|Bacteria,2GIZF@201174|Actinobacteria,4CRI8@84995|Rubrobacteria	84995|Rubrobacteria	T	GAF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF_3,GGDEF
BYD2_k127_8752545_2	1229780.BN381_430032	6.94e-181	598.0	COG0204@1|root,COG0560@1|root,COG0204@2|Bacteria,COG0560@2|Bacteria,2GKVA@201174|Actinobacteria,3UWPE@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	I	Phosphate acyltransferases	plsC2	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
BYD2_k127_8752545_6	1313172.YM304_21260	1.343e-69	251.0	COG0583@1|root,COG0583@2|Bacteria,2HF8Y@201174|Actinobacteria,4CN2C@84992|Acidimicrobiia	84992|Acidimicrobiia	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	ko:K04761	ko02026,map02026	-	-	-	ko00000,ko00001,ko03000	-	-	-	HTH_1,LysR_substrate
BYD2_k127_8752545_1	525909.Afer_1835	8.203e-213	668.0	COG0372@1|root,COG0372@2|Bacteria,2GJ7E@201174|Actinobacteria,4CMS9@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Citrate synthase, C-terminal domain	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
BYD2_k127_8752545_3	469383.Cwoe_0785	7.396e-113	375.0	COG0604@1|root,COG0604@2|Bacteria,2GN47@201174|Actinobacteria,4CRRX@84995|Rubrobacteria	84995|Rubrobacteria	C	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N,ADH_zinc_N_2
BYD2_k127_8752545_9	1112204.GPOL_c02910	4.456e-46	171.0	COG3304@1|root,COG3304@2|Bacteria,2IKS5@201174|Actinobacteria,4GE90@85026|Gordoniaceae	201174|Actinobacteria	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
BYD2_k127_8752545_8	1313172.YM304_21930	7.869e-50	186.0	COG3884@1|root,COG3884@2|Bacteria,2H0CD@201174|Actinobacteria,4CNBC@84992|Acidimicrobiia	84992|Acidimicrobiia	I	Acyl-ACP thioesterase	-	-	-	-	-	-	-	-	-	-	-	-	Acyl-ACP_TE
BYD2_k127_8752545_10	1156844.KB891850_gene3043	7.723e-37	146.0	COG0454@1|root,COG0456@2|Bacteria,2IQC7@201174|Actinobacteria	201174|Actinobacteria	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
BYD2_k127_8752545_7	43759.JNWK01000008_gene5084	1.653e-67	237.0	COG1075@1|root,COG1075@2|Bacteria,2GMZA@201174|Actinobacteria	201174|Actinobacteria	S	acetyltransferases and hydrolases with the alpha beta hydrolase fold	lpsA1	-	3.1.1.3	ko:K01046	ko00561,ko01100,map00561,map01100	M00098	R02250,R02687	RC00020,RC00037,RC00041,RC00094	ko00000,ko00001,ko00002,ko01000	-	-	-	Lipase_2,PGAP1
BYD2_k127_8752545_5	1313172.YM304_21200	3.869e-84	286.0	COG1960@1|root,COG1960@2|Bacteria,2GJ7S@201174|Actinobacteria	201174|Actinobacteria	I	acyl-CoA dehydrogenase	-	-	1.3.8.7	ko:K00249	ko00071,ko00280,ko00410,ko00640,ko01100,ko01110,ko01130,ko01200,ko01212,ko03320,map00071,map00280,map00410,map00640,map01100,map01110,map01130,map01200,map01212,map03320	M00013,M00036,M00087	R00924,R01175,R01279,R02661,R03172,R03777,R03857,R03990,R04095,R04432,R04751,R04754	RC00052,RC00068,RC00076,RC00095,RC00148,RC00246	ko00000,ko00001,ko00002,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
BYD2_k127_8754065_2	1123322.KB904735_gene1486	1.312e-69	238.0	COG1595@1|root,COG1595@2|Bacteria,2GJIZ@201174|Actinobacteria	201174|Actinobacteria	K	belongs to the sigma-70 factor family, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_8754065_1	67315.JOBD01000002_gene2906	1.916e-77	264.0	COG2353@1|root,COG2353@2|Bacteria,2GJUB@201174|Actinobacteria	201174|Actinobacteria	S	Belongs to the UPF0312 family	-	-	-	-	-	-	-	-	-	-	-	-	YceI
BYD2_k127_8754065_0	644283.Micau_3157	1.219e-83	279.0	COG0702@1|root,COG0702@2|Bacteria,2GM39@201174|Actinobacteria,4DC5F@85008|Micromonosporales	201174|Actinobacteria	GM	NAD(P)H-binding	-	-	-	-	-	-	-	-	-	-	-	-	NAD_binding_10
BYD2_k127_8763690_1	1229780.BN381_10313	3.422e-89	295.0	COG0488@1|root,COG0488@2|Bacteria,2GKBQ@201174|Actinobacteria,3UWE5@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	S	ABC transporter	yjjK	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
BYD2_k127_8763690_2	1206730.BAGA01000074_gene1825	3.631e-85	298.0	COG0529@1|root,COG2895@1|root,COG0529@2|Bacteria,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4FUHJ@85025|Nocardiaceae	201174|Actinobacteria	P	Catalyzes the synthesis of activated sulfate	cysN	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
BYD2_k127_8763690_0	1394178.AWOO02000030_gene4666	2.258e-120	391.0	COG2895@1|root,COG2895@2|Bacteria,2GJDX@201174|Actinobacteria,4EFW9@85012|Streptosporangiales	201174|Actinobacteria	P	Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily	cysC	GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006790,GO:0006793,GO:0006796,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009336,GO:0009605,GO:0009987,GO:0009991,GO:0010134,GO:0010438,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019419,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034599,GO:0040007,GO:0042221,GO:0042594,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0061695,GO:0070887,GO:0071496,GO:0071944,GO:1902494,GO:1902503,GO:1990234	2.7.1.25,2.7.7.4	ko:K00955,ko:K00956	ko00230,ko00261,ko00450,ko00920,ko01100,ko01120,ko01130,map00230,map00261,map00450,map00920,map01100,map01120,map01130	M00176,M00596	R00509,R00529,R04928,R04929	RC00002,RC00078,RC02809,RC02889	ko00000,ko00001,ko00002,ko01000	-	-	-	APS_kinase,GTP_EFTU
BYD2_k127_8765311_5	1120936.KB907223_gene2509	7.119e-19	88.0	COG1131@1|root,COG1131@2|Bacteria,2GIY8@201174|Actinobacteria	201174|Actinobacteria	V	ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_8765311_4	298655.KI912266_gene4457	3.457e-62	221.0	COG1733@1|root,COG1733@2|Bacteria,2GMK5@201174|Actinobacteria	201174|Actinobacteria	K	PFAM helix-turn-helix HxlR type	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
BYD2_k127_8765311_2	1112204.GPOL_c23660	1.629e-131	430.0	COG2141@1|root,COG2141@2|Bacteria,2GM7W@201174|Actinobacteria,4GBMN@85026|Gordoniaceae	201174|Actinobacteria	C	Luciferase-like monooxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_luciferase
BYD2_k127_8765311_3	1032480.MLP_19180	9.834e-112	375.0	COG2197@1|root,COG2197@2|Bacteria,2IATK@201174|Actinobacteria,4DQAB@85009|Propionibacteriales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	GerE
BYD2_k127_8765311_1	1229780.BN381_60023	2.246e-185	629.0	COG0457@1|root,COG2114@1|root,COG3899@1|root,COG0457@2|Bacteria,COG2114@2|Bacteria,COG3899@2|Bacteria,2GJRI@201174|Actinobacteria,3UXGT@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	T	Adenylyl- / guanylyl cyclase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,Guanylate_cyc,TPR_12
BYD2_k127_8765311_0	266117.Rxyl_2529	8.002e-313	983.0	COG2902@1|root,COG2902@2|Bacteria,2GK0C@201174|Actinobacteria,4CPJ1@84995|Rubrobacteria	84995|Rubrobacteria	E	Bacterial NAD-glutamate dehydrogenase	-	-	1.4.1.2	ko:K15371	ko00220,ko00250,ko00430,ko00910,ko01100,map00220,map00250,map00430,map00910,map01100	-	R00243	RC00006,RC02799	ko00000,ko00001,ko01000	-	-	-	Bac_GDH
BYD2_k127_8782387_17	1206743.BAGM01000092_gene4746	8.04e-44	168.0	COG0454@1|root,COG0456@2|Bacteria,2IQQX@201174|Actinobacteria,4G2PZ@85025|Nocardiaceae	201174|Actinobacteria	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
BYD2_k127_8782387_8	1313172.YM304_33030	3.717e-81	286.0	COG0084@1|root,COG0084@2|Bacteria,2GMJJ@201174|Actinobacteria,4CN2X@84992|Acidimicrobiia	84992|Acidimicrobiia	L	TatD related DNase	-	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
BYD2_k127_8782387_13	1048339.KB913029_gene525	6.033e-70	246.0	COG0030@1|root,COG0030@2|Bacteria,2GKBT@201174|Actinobacteria,4ES96@85013|Frankiales	201174|Actinobacteria	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
BYD2_k127_8782387_10	1229780.BN381_20098	6.297e-78	282.0	COG1947@1|root,COG1947@2|Bacteria,2GKXD@201174|Actinobacteria,3UWNZ@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	F	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
BYD2_k127_8782387_22	543632.JOJL01000003_gene8559	1.117e-14	81.0	COG1595@1|root,COG1595@2|Bacteria,2GKDD@201174|Actinobacteria,4DCE2@85008|Micromonosporales	201174|Actinobacteria	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
BYD2_k127_8782387_2	1299327.I546_0475	2.002e-151	501.0	COG1063@1|root,COG1063@2|Bacteria,2IBQC@201174|Actinobacteria,23300@1762|Mycobacteriaceae	201174|Actinobacteria	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
BYD2_k127_8782387_9	557599.MKAN_19785	5.955e-79	280.0	COG0300@1|root,COG0300@2|Bacteria,2GMI7@201174|Actinobacteria,2389H@1762|Mycobacteriaceae	201174|Actinobacteria	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
BYD2_k127_8782387_24	251221.35213777	6.001e-09	68.0	COG3055@1|root,COG3401@1|root,COG3055@2|Bacteria,COG3401@2|Bacteria,1GCFC@1117|Cyanobacteria	1117|Cyanobacteria	S	Kelch motif	-	-	-	-	-	-	-	-	-	-	-	-	Kelch_1,Kelch_6,Malectin
BYD2_k127_8782387_23	1404245.CGLY_05625	1.331e-10	73.0	COG4335@1|root,COG4335@2|Bacteria,2HDE9@201174|Actinobacteria,22MW4@1653|Corynebacteriaceae	201174|Actinobacteria	L	DNA alkylation repair	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
BYD2_k127_8782387_21	379066.GAU_1019	2.4e-16	89.0	COG4335@1|root,COG4335@2|Bacteria,1ZUM8@142182|Gemmatimonadetes	142182|Gemmatimonadetes	L	DNA alkylation repair enzyme	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
BYD2_k127_8782387_11	546414.Deide_23150	8.046e-73	256.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	sigE1	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4,Sigma70_r4_2
BYD2_k127_8782387_16	1415166.NONO_c74520	1.227e-49	179.0	COG0346@1|root,COG0346@2|Bacteria,2IS2C@201174|Actinobacteria,4G4EB@85025|Nocardiaceae	201174|Actinobacteria	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8782387_1	1385520.N802_02040	3.242e-239	776.0	COG0308@1|root,COG0308@2|Bacteria,2GJWF@201174|Actinobacteria,4FEJG@85021|Intrasporangiaceae	201174|Actinobacteria	E	Peptidase family M1 domain	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M1
BYD2_k127_8782387_14	570268.ANBB01000063_gene898	1.88e-68	262.0	COG0515@1|root,COG0515@2|Bacteria,2GIV0@201174|Actinobacteria	201174|Actinobacteria	KLT	serine threonine protein kinase	-	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
BYD2_k127_8782387_4	1463841.JOIR01000022_gene3281	2.994e-130	422.0	COG0604@1|root,COG0604@2|Bacteria,2GIS3@201174|Actinobacteria	201174|Actinobacteria	C	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N_2
BYD2_k127_8782387_0	1380393.JHVP01000004_gene681	2.811e-243	762.0	COG1053@1|root,COG1053@2|Bacteria,2GIXG@201174|Actinobacteria,4EUXT@85013|Frankiales	201174|Actinobacteria	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2
BYD2_k127_8782387_6	1146883.BLASA_1402	3.201e-108	378.0	COG3284@1|root,COG3284@2|Bacteria	2|Bacteria	KQ	transcription factor binding	-	-	-	-	-	-	-	-	-	-	-	-	GAF,HTH_8,Sigma54_activ_2
BYD2_k127_8782387_3	882086.SacxiDRAFT_3798	1.264e-132	427.0	COG2159@1|root,COG2159@2|Bacteria,2GMQY@201174|Actinobacteria,4DZEJ@85010|Pseudonocardiales	201174|Actinobacteria	S	Amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
BYD2_k127_8782387_19	570268.ANBB01000038_gene3394	1.867e-21	109.0	COG1846@1|root,COG1846@2|Bacteria,2IJFJ@201174|Actinobacteria,4EPIG@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
BYD2_k127_8782387_18	1380390.JIAT01000010_gene4348	6.356e-39	149.0	COG4572@1|root,COG4572@2|Bacteria,2IMHQ@201174|Actinobacteria	201174|Actinobacteria	S	PFAM ChaB family protein	-	-	-	-	-	-	-	-	-	-	-	-	ChaB,Rho_N
BYD2_k127_8782387_7	1394178.AWOO02000009_gene4241	1.125e-105	351.0	COG0583@1|root,COG0583@2|Bacteria,2I9HH@201174|Actinobacteria,4EGQQ@85012|Streptosporangiales	201174|Actinobacteria	K	Bacterial regulatory helix-turn-helix protein, lysR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
BYD2_k127_8782387_12	1214101.BN159_7882	1.443e-72	259.0	COG1748@1|root,COG1748@2|Bacteria,2IHCF@201174|Actinobacteria	201174|Actinobacteria	E	Saccharopine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase,Sacchrp_dh_NADP
BYD2_k127_8782387_15	1121946.AUAX01000001_gene2403	5.226e-59	220.0	2F399@1|root,33W3K@2|Bacteria,2IMEX@201174|Actinobacteria	201174|Actinobacteria	S	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_23
BYD2_k127_8782387_5	358823.DF19_29080	1.551e-119	390.0	COG1073@1|root,COG1073@2|Bacteria,2I345@201174|Actinobacteria	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_8791930_2	1122622.ATWJ01000010_gene1419	1.472e-218	691.0	COG0659@1|root,COG0659@2|Bacteria,2GJCB@201174|Actinobacteria,4FF9M@85021|Intrasporangiaceae	201174|Actinobacteria	P	Sulfate permease family	-	GO:0000103,GO:0000166,GO:0003333,GO:0003674,GO:0005215,GO:0005310,GO:0005326,GO:0005342,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006790,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0008152,GO:0008272,GO:0008509,GO:0008514,GO:0009987,GO:0015075,GO:0015103,GO:0015116,GO:0015138,GO:0015141,GO:0015171,GO:0015172,GO:0015179,GO:0015183,GO:0015238,GO:0015318,GO:0015556,GO:0015698,GO:0015711,GO:0015740,GO:0015741,GO:0015744,GO:0015800,GO:0015807,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0017076,GO:0019001,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070778,GO:0071422,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0097159,GO:0098656,GO:0098660,GO:0098661,GO:1901265,GO:1901363,GO:1901682,GO:1902358,GO:1902475,GO:1903825,GO:1905039	-	ko:K03321	-	-	-	-	ko00000,ko02000	2.A.53.3	-	-	STAS,Sulfate_transp
BYD2_k127_8791930_16	1123024.AUII01000031_gene526	3.561e-54	197.0	COG0454@1|root,COG0456@2|Bacteria,2I9Y3@201174|Actinobacteria,4E6FQ@85010|Pseudonocardiales	201174|Actinobacteria	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
BYD2_k127_8791930_6	1403819.BATR01000162_gene5394	1.594e-107	359.0	COG2227@1|root,COG2227@2|Bacteria	2|Bacteria	H	3-demethylubiquinone-9 3-O-methyltransferase activity	-	-	2.1.1.222,2.1.1.64	ko:K00568	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00117	R04988,R05614,R08769,R08781	RC00003,RC00392,RC01895	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,Methyltransf_31
BYD2_k127_8791930_11	1463936.JOJI01000058_gene6134	7.131e-80	297.0	COG3899@1|root,COG3903@1|root,COG3899@2|Bacteria,COG3903@2|Bacteria,2GIZ1@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,Trans_reg_C
BYD2_k127_8791930_18	1380394.JADL01000001_gene2170	4.594e-34	136.0	COG0346@1|root,COG0346@2|Bacteria,1NFR3@1224|Proteobacteria,2UMIM@28211|Alphaproteobacteria	28211|Alphaproteobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8791930_13	443255.SCLAV_1880	7.9e-66	236.0	COG2084@1|root,COG2084@2|Bacteria,2GNB0@201174|Actinobacteria	201174|Actinobacteria	I	3-hydroxyisobutyrate dehydrogenase	-	-	1.1.1.31	ko:K00020	ko00280,ko01100,map00280,map01100	-	R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	Lumazine_bd_2,NAD_binding_11,NAD_binding_2,Ribonuc_L-PSP
BYD2_k127_8791930_17	397278.JOJN01000001_gene2849	6.097e-49	181.0	COG3945@1|root,COG3945@2|Bacteria,2I92G@201174|Actinobacteria,4DS57@85009|Propionibacteriales	201174|Actinobacteria	S	F420H(2)-dependent quinone reductase	-	-	-	-	-	-	-	-	-	-	-	-	F420H2_quin_red
BYD2_k127_8791930_19	1394178.AWOO02000024_gene5581	1.14e-31	131.0	COG1309@1|root,COG1309@2|Bacteria,2IMUC@201174|Actinobacteria	201174|Actinobacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8791930_8	585531.HMPREF0063_10393	1.963e-100	336.0	COG0410@1|root,COG0410@2|Bacteria,2GKSQ@201174|Actinobacteria,4DPMH@85009|Propionibacteriales	201174|Actinobacteria	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K01996	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran
BYD2_k127_8791930_7	935866.JAER01000010_gene4130	1.642e-104	353.0	COG0411@1|root,COG0411@2|Bacteria,2GMEE@201174|Actinobacteria,4DPBA@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid ATP-binding cassette transporter	-	-	-	ko:K01995	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	ABC_tran,BCA_ABC_TP_C
BYD2_k127_8791930_1	408672.NBCG_01838	2.917e-243	779.0	COG1022@1|root,COG1022@2|Bacteria,2GIXQ@201174|Actinobacteria,4DPKK@85009|Propionibacteriales	201174|Actinobacteria	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
BYD2_k127_8791930_9	408672.NBCG_01837	3.989e-97	351.0	COG0559@1|root,COG0559@2|Bacteria,2HDZ9@201174|Actinobacteria,4DPF0@85009|Propionibacteriales	201174|Actinobacteria	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_8791930_5	1068978.AMETH_0141	1.292e-115	398.0	COG4177@1|root,COG4177@2|Bacteria,2GMGD@201174|Actinobacteria,4DYYG@85010|Pseudonocardiales	201174|Actinobacteria	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998	ko02010,ko02024,map02010,map02024	M00237	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4	-	-	BPD_transp_2
BYD2_k127_8791930_4	408672.NBCG_01835	1.295e-128	423.0	COG0683@1|root,COG0683@2|Bacteria,2GMCF@201174|Actinobacteria,4DRHN@85009|Propionibacteriales	201174|Actinobacteria	E	Periplasmic binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_6
BYD2_k127_8791930_3	502025.Hoch_1494	3.184e-165	546.0	2CC7E@1|root,2Z7WG@2|Bacteria,1R77M@1224|Proteobacteria	1224|Proteobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8791930_14	2074.JNYD01000003_gene3471	1.556e-58	213.0	2C7TJ@1|root,31RF6@2|Bacteria,2GP9X@201174|Actinobacteria,4E4V6@85010|Pseudonocardiales	201174|Actinobacteria	S	Mycothiol maleylpyruvate isomerase N-terminal domain	-	-	5.2.1.4	ko:K16163	ko00350,ko01100,ko01120,map00350,map01100,map01120	-	R03868	RC00867	ko00000,ko00001,ko01000	-	-	-	MDMPI_N
BYD2_k127_8791930_0	373994.Riv7116_5818	4.951e-258	820.0	COG1554@1|root,COG1554@2|Bacteria,1G0DN@1117|Cyanobacteria,1HIEI@1161|Nostocales	1117|Cyanobacteria	G	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
BYD2_k127_8791930_12	1089545.KB913037_gene7597	3.429e-68	248.0	COG1476@1|root,COG1476@2|Bacteria,2HQZ1@201174|Actinobacteria,4EDFX@85010|Pseudonocardiales	201174|Actinobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
BYD2_k127_8791930_20	1089545.KB913037_gene7598	5.947e-31	131.0	2E0WM@1|root,32WDM@2|Bacteria,2HRJ5@201174|Actinobacteria,4E7DU@85010|Pseudonocardiales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8791930_15	208444.JNYY01000003_gene1806	4.029e-55	201.0	COG0717@1|root,COG0717@2|Bacteria	2|Bacteria	F	dUTP biosynthetic process	-	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
BYD2_k127_8791930_10	749927.AMED_6750	1.333e-95	324.0	COG0611@1|root,COG0611@2|Bacteria,2I8EE@201174|Actinobacteria	201174|Actinobacteria	H	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1	-	-	2.7.4.16	ko:K00946	ko00730,ko01100,map00730,map01100	M00127	R00617	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
BYD2_k127_8833406_0	1394178.AWOO02000137_gene452	1.445e-138	450.0	COG3328@1|root,COG3328@2|Bacteria,2GM8F@201174|Actinobacteria,4EKU3@85012|Streptosporangiales	201174|Actinobacteria	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
BYD2_k127_8833406_1	1029824.AFID01000014_gene36	1.288e-74	267.0	COG3464@1|root,COG3464@2|Bacteria,2GJK7@201174|Actinobacteria,1WB21@1268|Micrococcaceae	201174|Actinobacteria	L	Helix-turn-helix domain of transposase family ISL3	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,HTH_Tnp_ISL3,zf-ISL3
BYD2_k127_8839654_1	1110697.NCAST_23_00160	9.875e-68	249.0	2C56P@1|root,2ZJ2W@2|Bacteria,2IKDI@201174|Actinobacteria,4G0AJ@85025|Nocardiaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8839654_0	1211815.CBYP010000067_gene114	8.741e-148	476.0	COG0318@1|root,COG0318@2|Bacteria,2GJAA@201174|Actinobacteria,4EU2I@85013|Frankiales	201174|Actinobacteria	IQ	PFAM AMP-dependent synthetase and ligase	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
BYD2_k127_8848064_1	1229780.BN381_130078	2.203e-134	432.0	COG1053@1|root,COG1053@2|Bacteria,2GJ45@201174|Actinobacteria,3UX16@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	C	Fumarate reductase flavoprotein C-term	sdhA	-	1.3.5.1,1.3.5.4,1.4.3.16	ko:K00239,ko:K00278	ko00020,ko00190,ko00250,ko00650,ko00720,ko00760,ko01100,ko01110,ko01120,ko01130,ko01200,ko05134,map00020,map00190,map00250,map00650,map00720,map00760,map01100,map01110,map01120,map01130,map01200,map05134	M00009,M00011,M00115,M00149,M00173,M00374,M00376	R00357,R00481,R02164	RC00006,RC00045,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
BYD2_k127_8848064_3	1229780.BN381_130077	2.438e-107	368.0	COG0479@1|root,COG0479@2|Bacteria,2GJPS@201174|Actinobacteria	201174|Actinobacteria	C	succinate dehydrogenase	sdhB	-	1.3.5.1,1.3.5.4	ko:K00240	ko00020,ko00190,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00190,map00650,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00149,M00173,M00374,M00376	R02164	RC00045	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer2_3,Fer4_7,Fer4_8
BYD2_k127_8848064_12	643648.Slip_0172	5.855e-62	233.0	COG2148@1|root,COG2148@2|Bacteria,1UVWG@1239|Firmicutes,25KNI@186801|Clostridia,42KS8@68298|Syntrophomonadaceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
BYD2_k127_8848064_7	1030157.AFMP01000036_gene2642	3.69e-74	272.0	COG1181@1|root,COG1181@2|Bacteria,1QURQ@1224|Proteobacteria,2U2UD@28211|Alphaproteobacteria,2K3KS@204457|Sphingomonadales	204457|Sphingomonadales	M	ATP-grasp domain	-	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-grasp_3
BYD2_k127_8848064_17	1219045.BV98_001667	3.295e-48	183.0	COG0546@1|root,COG0546@2|Bacteria,1QURP@1224|Proteobacteria,2U7IH@28211|Alphaproteobacteria,2K4W7@204457|Sphingomonadales	204457|Sphingomonadales	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
BYD2_k127_8848064_5	1229780.BN381_50026	4.483e-104	363.0	COG0438@1|root,COG0438@2|Bacteria,2GNIU@201174|Actinobacteria	201174|Actinobacteria	M	Glycosyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_8848064_13	1229780.BN381_50025	2.074e-60	219.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Polysacc_deac_1
BYD2_k127_8848064_6	710696.Intca_2625	5.839e-86	297.0	COG3153@1|root,COG3153@2|Bacteria,2I8ZE@201174|Actinobacteria,4FFDY@85021|Intrasporangiaceae	201174|Actinobacteria	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
BYD2_k127_8848064_4	67352.JODS01000002_gene1704	3.788e-105	379.0	COG3291@1|root,COG3291@2|Bacteria	2|Bacteria	S	metallopeptidase activity	-	-	3.2.1.4	ko:K01179	ko00500,ko01100,map00500,map01100	-	R06200,R11307,R11308	-	ko00000,ko00001,ko01000	-	GH5,GH9	-	PA14,PKD,PPC,Peptidase_M9,Peptidase_M9_N,Ricin_B_lectin
BYD2_k127_8848064_16	330214.NIDE2698	6.332e-50	205.0	COG0726@1|root,COG0726@2|Bacteria	2|Bacteria	G	polysaccharide deacetylase	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
BYD2_k127_8848064_20	795666.MW7_0745	3.092e-20	104.0	COG0438@1|root,COG0438@2|Bacteria,1MU9C@1224|Proteobacteria,2VIBU@28216|Betaproteobacteria,1K5VW@119060|Burkholderiaceae	28216|Betaproteobacteria	M	Glycosyl transferase 4-like	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_trans_4_4,Glyco_transf_4,Glycos_transf_1
BYD2_k127_8848064_23	187272.Mlg_0132	1.632e-08	65.0	COG1073@1|root,COG1216@1|root,COG1073@2|Bacteria,COG1216@2|Bacteria,1MZSD@1224|Proteobacteria,1S9D2@1236|Gammaproteobacteria,1X2DR@135613|Chromatiales	135613|Chromatiales	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
BYD2_k127_8848064_22	1218074.BAXZ01000014_gene2977	2.488e-09	69.0	COG1073@1|root,COG1073@2|Bacteria,1RA55@1224|Proteobacteria,2VXHH@28216|Betaproteobacteria,1K0DN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
BYD2_k127_8848064_0	1133850.SHJG_0589	2.15e-158	516.0	COG1020@1|root,COG1020@2|Bacteria,2GP0R@201174|Actinobacteria	201174|Actinobacteria	Q	Belongs to the ATP-dependent AMP-binding enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
BYD2_k127_8848064_25	1158760.AQXP01000053_gene1474	0.0003438	51.0	COG0236@1|root,COG0236@2|Bacteria,1N83X@1224|Proteobacteria,1SD6R@1236|Gammaproteobacteria,1WZDW@135613|Chromatiales	135613|Chromatiales	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
BYD2_k127_8848064_2	877420.ATVW01000022_gene220	1.536e-120	394.0	COG2089@1|root,COG2089@2|Bacteria,1TS09@1239|Firmicutes,249DN@186801|Clostridia,27J6J@186928|unclassified Lachnospiraceae	186801|Clostridia	M	NeuB family	-	-	-	-	-	-	-	-	-	-	-	-	NeuB
BYD2_k127_8848064_9	926569.ANT_06450	5.613e-72	261.0	COG1028@1|root,COG1028@2|Bacteria,2G6RP@200795|Chloroflexi	200795|Chloroflexi	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.127	ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
BYD2_k127_8848064_15	228410.NE1568	1.097e-52	207.0	COG0673@1|root,COG0673@2|Bacteria,1MUP0@1224|Proteobacteria,2VWUY@28216|Betaproteobacteria,3722P@32003|Nitrosomonadales	28216|Betaproteobacteria	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
BYD2_k127_8848064_11	926569.ANT_06460	7.281e-71	250.0	COG1083@1|root,COG1778@1|root,COG1083@2|Bacteria,COG1778@2|Bacteria	2|Bacteria	S	3-deoxy-manno-octulosonate-8-phosphatase activity	neuA	-	2.7.7.43,3.1.3.45	ko:K00983,ko:K03270	ko00520,ko00540,ko01100,map00520,map00540,map01100	M00063	R01117,R03350,R04215	RC00017,RC00152	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	CTP_transf_3,Hydrolase_3
BYD2_k127_8848064_14	1121440.AUMA01000005_gene2686	1.031e-56	204.0	COG1778@1|root,COG1778@2|Bacteria,1RH85@1224|Proteobacteria,435RJ@68525|delta/epsilon subdivisions,2X066@28221|Deltaproteobacteria,2MAT1@213115|Desulfovibrionales	28221|Deltaproteobacteria	S	haloacid dehalogenase-like hydrolase	-	-	3.1.3.45	ko:K03270	ko00540,ko01100,map00540,map01100	M00063	R03350	RC00017	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3
BYD2_k127_8848064_21	1123508.JH636444_gene5452	1.938e-19	105.0	COG1063@1|root,COG1063@2|Bacteria,2J0NZ@203682|Planctomycetes	203682|Planctomycetes	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N,GFO_IDH_MocA
BYD2_k127_8848064_8	298654.FraEuI1c_0127	1.083e-72	278.0	COG2303@1|root,COG2303@2|Bacteria,2I5YA@201174|Actinobacteria,4EVKJ@85013|Frankiales	201174|Actinobacteria	C	GMC oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	DAO,FAD_binding_2,FAD_binding_3,GMC_oxred_C,GMC_oxred_N
BYD2_k127_8848064_18	1121439.dsat_1887	1.63e-44	184.0	COG0438@1|root,COG0438@2|Bacteria,1RBQV@1224|Proteobacteria,42Z9P@68525|delta/epsilon subdivisions,2WU4Z@28221|Deltaproteobacteria,2MAYS@213115|Desulfovibrionales	28221|Deltaproteobacteria	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8848064_10	1246995.AFR_15970	1.032e-71	267.0	COG1131@1|root,COG1131@2|Bacteria	2|Bacteria	V	ATPase activity	MA20_23390	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
BYD2_k127_8848064_19	1246995.AFR_15965	3.895e-33	147.0	COG0842@1|root,COG0842@2|Bacteria,2H4BZ@201174|Actinobacteria	201174|Actinobacteria	U	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
BYD2_k127_8848064_24	1218074.BAXZ01000014_gene2977	2.474e-07	61.0	COG1073@1|root,COG1073@2|Bacteria,1RA55@1224|Proteobacteria,2VXHH@28216|Betaproteobacteria,1K0DN@119060|Burkholderiaceae	28216|Betaproteobacteria	S	Serine aminopeptidase, S33	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6,Hydrolase_4
BYD2_k127_892093_1	1502852.FG94_04343	3.146e-12	74.0	COG3595@1|root,COG3595@2|Bacteria,1PWK1@1224|Proteobacteria,2WC4H@28216|Betaproteobacteria,476ZB@75682|Oxalobacteraceae	28216|Betaproteobacteria	S	Putative auto-transporter adhesin, head GIN domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF2807
BYD2_k127_892093_0	1463820.JOGW01000003_gene7237	3.753e-274	864.0	COG1472@1|root,COG1472@2|Bacteria,2GJ5H@201174|Actinobacteria	201174|Actinobacteria	G	hydrolase, family 3	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Glyco_hydro_3,Glyco_hydro_3_C
BYD2_k127_8934562_0	1210884.HG799462_gene8936	7.655e-281	874.0	COG2931@1|root,COG2931@2|Bacteria,2IZ0P@203682|Planctomycetes	203682|Planctomycetes	Q	Haemolysin-type calcium-binding repeat (2 copies)	-	-	-	-	-	-	-	-	-	-	-	-	HemolysinCabind
BYD2_k127_8934562_1	1298867.AUES01000051_gene4507	4.896e-137	458.0	COG0845@1|root,COG0845@2|Bacteria,1N97Q@1224|Proteobacteria,2U22Z@28211|Alphaproteobacteria,3K3DU@41294|Bradyrhizobiaceae	28211|Alphaproteobacteria	M	Barrel-sandwich domain of CusB or HlyD membrane-fusion	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,GAF,HlyD_3,HlyD_D23
BYD2_k127_8934562_2	330214.NIDE2723	7.343e-104	353.0	COG0845@1|root,COG1994@1|root,COG0845@2|Bacteria,COG1994@2|Bacteria	2|Bacteria	S	metallopeptidase activity	yydH	-	-	ko:K01993,ko:K13408,ko:K16922	ko04626,map04626	M00339	-	-	ko00000,ko00001,ko00002,ko01002,ko02000,ko02044	8.A.1	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23,PqqD
BYD2_k127_8939908_1	479431.Namu_5287	3.639e-200	626.0	COG1529@1|root,COG1529@2|Bacteria,2GIVI@201174|Actinobacteria,4ETP4@85013|Frankiales	201174|Actinobacteria	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	coxL	-	1.2.5.3	ko:K03520	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
BYD2_k127_8939908_6	35754.JNYJ01000054_gene9714	6.761e-84	290.0	COG1975@1|root,COG3350@1|root,COG1975@2|Bacteria,COG3350@2|Bacteria,2IA9U@201174|Actinobacteria,4DDBA@85008|Micromonosporales	201174|Actinobacteria	O	XdhC and CoxI family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI,YHS
BYD2_k127_8939908_3	1157637.KB892124_gene788	2.867e-126	419.0	COG0714@1|root,COG0714@2|Bacteria,2GMM2@201174|Actinobacteria	201174|Actinobacteria	O	ATPase associated with various cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
BYD2_k127_8939908_5	469383.Cwoe_3031	6.978e-100	362.0	COG3552@1|root,COG3552@2|Bacteria,2GNTS@201174|Actinobacteria,4CRRF@84995|Rubrobacteria	84995|Rubrobacteria	S	von Willebrand factor, type A	-	-	-	ko:K07161	-	-	-	-	ko00000	-	-	-	VWA_CoxE
BYD2_k127_8939908_10	1240349.ANGC01000015_gene669	1.686e-59	214.0	COG0346@1|root,COG0346@2|Bacteria,2IHQQ@201174|Actinobacteria,4G2SZ@85025|Nocardiaceae	201174|Actinobacteria	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase
BYD2_k127_8939908_13	561175.KB894093_gene4027	1.954e-43	159.0	COG0640@1|root,COG0640@2|Bacteria,2GNW2@201174|Actinobacteria,4EJZH@85012|Streptosporangiales	201174|Actinobacteria	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
BYD2_k127_8939908_12	37919.EP51_16930	7.472e-48	175.0	COG2315@1|root,COG2315@2|Bacteria,2II89@201174|Actinobacteria,4G2AC@85025|Nocardiaceae	201174|Actinobacteria	S	YjbR	-	-	-	-	-	-	-	-	-	-	-	-	YjbR
BYD2_k127_8939908_9	1120950.KB892776_gene812	6.342e-65	231.0	COG1670@1|root,COG1670@2|Bacteria,2GP87@201174|Actinobacteria,4DQYP@85009|Propionibacteriales	201174|Actinobacteria	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
BYD2_k127_8939908_15	1227500.C494_03885	1.302e-05	58.0	arCOG03919@1|root,arCOG03919@2157|Archaea,2XUW0@28890|Euryarchaeota,23T0E@183963|Halobacteria	183963|Halobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_8939908_8	710687.KI912270_gene1738	8.191e-67	237.0	COG0500@1|root,COG2226@2|Bacteria,2IHXS@201174|Actinobacteria,23FDY@1762|Mycobacteriaceae	201174|Actinobacteria	Q	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_8939908_7	1449976.KALB_2438	2.485e-78	269.0	COG2207@1|root,COG2207@2|Bacteria,2IGXZ@201174|Actinobacteria,4EF54@85010|Pseudonocardiales	201174|Actinobacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
BYD2_k127_8939908_11	1229780.BN381_80140	6.938e-53	190.0	COG0782@1|root,COG0782@2|Bacteria,2GNZV@201174|Actinobacteria,3UWPU@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0071944	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
BYD2_k127_8939908_4	525909.Afer_1536	4.456e-125	411.0	COG0473@1|root,COG0473@2|Bacteria,2GK44@201174|Actinobacteria,4CMRK@84992|Acidimicrobiia	84992|Acidimicrobiia	C	Isocitrate/isopropylmalate dehydrogenase	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
BYD2_k127_8939908_2	1313172.YM304_13000	3.968e-151	482.0	COG0115@1|root,COG0115@2|Bacteria,2GKJ1@201174|Actinobacteria,4CMVG@84992|Acidimicrobiia	84992|Acidimicrobiia	E	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family	ilvE	-	2.6.1.42	ko:K00826	ko00270,ko00280,ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R10991	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
BYD2_k127_8939908_0	1229780.BN381_80143	1.704e-233	734.0	COG0119@1|root,COG0119@2|Bacteria,2GKYT@201174|Actinobacteria,3UWEK@52018|unclassified Actinobacteria (class)	201174|Actinobacteria	E	LeuA allosteric (dimerisation) domain	leuA2	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,LeuA_dimer
BYD2_k127_8939908_14	1313172.YM304_13050	1.708e-41	158.0	2F7CY@1|root,33ZTZ@2|Bacteria,2H76P@201174|Actinobacteria,4CNCM@84992|Acidimicrobiia	84992|Acidimicrobiia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_95220_1	298654.FraEuI1c_2880	2.554e-71	244.0	COG1024@1|root,COG1024@2|Bacteria,2GJ0N@201174|Actinobacteria,4ESJA@85013|Frankiales	201174|Actinobacteria	I	Enoyl-CoA hydratase	-	-	4.2.1.17,4.2.1.18	ko:K01692,ko:K13766	ko00071,ko00280,ko00281,ko00310,ko00360,ko00362,ko00380,ko00410,ko00627,ko00640,ko00650,ko00903,ko00930,ko01100,ko01110,ko01120,ko01130,ko01212,map00071,map00280,map00281,map00310,map00360,map00362,map00380,map00410,map00627,map00640,map00650,map00903,map00930,map01100,map01110,map01120,map01130,map01212	M00032,M00036,M00087	R02085,R03026,R03045,R04137,R04170,R04204,R04224,R04738,R04740,R04744,R04746,R04749,R05595,R06411,R06412,R06942,R08093	RC00831,RC00834,RC01086,RC01095,RC01098,RC01103,RC01217,RC02115,RC02416	ko00000,ko00001,ko00002,ko01000	-	-	-	ECH_1
BYD2_k127_95220_0	1313172.YM304_01440	2.52e-159	520.0	COG2070@1|root,COG2070@2|Bacteria,2GKGT@201174|Actinobacteria	201174|Actinobacteria	S	2-nitropropane dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	NMO
BYD2_k127_95220_2	1440774.Y900_023345	0.0005322	47.0	2EGHN@1|root,33A9R@2|Bacteria,2GSZ1@201174|Actinobacteria,23BB4@1762|Mycobacteriaceae	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_971320_4	1173028.ANKO01000060_gene2912	2.528e-16	78.0	COG0518@1|root,COG0519@1|root,COG0518@2|Bacteria,COG0519@2|Bacteria,1G06N@1117|Cyanobacteria,1H7R0@1150|Oscillatoriales	1117|Cyanobacteria	F	Catalyzes the synthesis of GMP from XMP	guaA	GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
BYD2_k127_971320_0	2002.JOEQ01000005_gene3672	6.31e-186	608.0	COG0421@1|root,COG0421@2|Bacteria,2I3HX@201174|Actinobacteria,4EHKS@85012|Streptosporangiales	201174|Actinobacteria	E	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
BYD2_k127_971320_2	1206101.AZXC01000024_gene811	4.099e-67	233.0	COG0662@1|root,COG0662@2|Bacteria,2IHU8@201174|Actinobacteria	201174|Actinobacteria	G	PFAM Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
BYD2_k127_971320_1	1056816.JAFQ01000004_gene4078	2.07e-105	351.0	COG0596@1|root,COG0596@2|Bacteria,2HHT8@201174|Actinobacteria,4G09S@85025|Nocardiaceae	201174|Actinobacteria	S	Alpha/beta hydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_6
BYD2_k127_981239_7	1146883.BLASA_4061	7.52e-128	418.0	COG1409@1|root,COG1409@2|Bacteria,2GP0C@201174|Actinobacteria,4EX0J@85013|Frankiales	201174|Actinobacteria	S	Purple acid Phosphatase, N-terminal domain	ppe2	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	-	-	-	-	-	-	-	-	-	Metallophos,Pur_ac_phosph_N,TAT_signal
BYD2_k127_981239_0	309801.trd_A0628	0.0	1217.0	COG0243@1|root,COG0243@2|Bacteria,2GABT@200795|Chloroflexi,27Z9X@189775|Thermomicrobia	189775|Thermomicrobia	C	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Molybdop_Fe4S4,Molybdopterin,Molydop_binding
BYD2_k127_981239_4	1123024.AUII01000032_gene3777	1.155e-153	500.0	COG0437@1|root,COG3301@1|root,COG0437@2|Bacteria,COG3301@2|Bacteria,2H0W0@201174|Actinobacteria	201174|Actinobacteria	C	PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_11,Fer4_3,Fer4_4,Fer4_7,NrfD
BYD2_k127_981239_12	469383.Cwoe_0229	3.349e-77	266.0	COG1396@1|root,COG1396@2|Bacteria,2GK1R@201174|Actinobacteria,4CRR7@84995|Rubrobacteria	84995|Rubrobacteria	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
BYD2_k127_981239_17	1341646.CBMO010000106_gene4047	4.161e-45	173.0	2DMP1@1|root,32SS8@2|Bacteria,2IJVX@201174|Actinobacteria,239AG@1762|Mycobacteriaceae	201174|Actinobacteria	S	Protein of unknown function (DUF3237)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3237
BYD2_k127_981239_20	324602.Caur_3769	1.3e-14	86.0	COG2152@1|root,COG3055@1|root,COG3266@1|root,COG5624@1|root,COG2152@2|Bacteria,COG3055@2|Bacteria,COG3266@2|Bacteria,COG5624@2|Bacteria,2G86G@200795|Chloroflexi,376E1@32061|Chloroflexia	32061|Chloroflexia	G	LamG domain protein jellyroll fold domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Laminin_G_3
BYD2_k127_981239_8	1123024.AUII01000024_gene244	4.328e-127	425.0	COG2132@1|root,COG4454@1|root,COG2132@2|Bacteria,COG4454@2|Bacteria,2GPUP@201174|Actinobacteria,4E20Z@85010|Pseudonocardiales	201174|Actinobacteria	PQ	Multicopper oxidase	aniA	-	1.7.2.1	ko:K00368	ko00910,ko01120,map00910,map01120	M00529	R00783,R00785	RC00086	ko00000,ko00001,ko00002,ko01000	-	-	-	Cu-oxidase_2,Cu-oxidase_3,Cupredoxin_1
BYD2_k127_981239_6	35754.JNYJ01000015_gene8424	5.254e-132	434.0	COG3570@1|root,COG3570@2|Bacteria,2GZSC@201174|Actinobacteria,4DC6T@85008|Micromonosporales	201174|Actinobacteria	V	Aminoglycoside/hydroxyurea antibiotic resistance kinase	-	-	2.7.1.72	ko:K04343	-	M00766	R02225	RC00002,RC00078	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	APH_6_hur
BYD2_k127_981239_11	561175.KB894093_gene2781	2.278e-84	299.0	COG0596@1|root,COG0596@2|Bacteria,2GKX3@201174|Actinobacteria	201174|Actinobacteria	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_981239_14	67281.JNZZ01000016_gene6115	2.119e-64	238.0	COG2133@1|root,COG2133@2|Bacteria,2I9ZW@201174|Actinobacteria,41AW1@629295|Streptomyces griseus group	201174|Actinobacteria	G	Glucose / Sorbosone dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CBM_2,GSDH
BYD2_k127_981239_2	369723.Strop_1330	2.146e-245	769.0	COG2146@1|root,COG2220@1|root,COG2146@2|Bacteria,COG2220@2|Bacteria,2GP4N@201174|Actinobacteria,4DBJI@85008|Micromonosporales	201174|Actinobacteria	P	Rieske 2Fe-2S	-	-	-	ko:K14952	ko05152,map05152	-	-	-	ko00000,ko00001	-	-	-	Lactamase_B_3,Rieske
BYD2_k127_981239_9	35754.JNYJ01000011_gene736	3.924e-126	439.0	COG2909@1|root,COG2909@2|Bacteria,2GJAR@201174|Actinobacteria,4DH9I@85008|Micromonosporales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_981239_18	710696.Intca_0369	3.448e-31	143.0	COG0596@1|root,COG1506@1|root,COG3710@1|root,COG0596@2|Bacteria,COG1506@2|Bacteria,COG3710@2|Bacteria,2HASC@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
BYD2_k127_981239_13	1123024.AUII01000052_gene3914	8.764e-71	250.0	COG0500@1|root,COG2226@2|Bacteria,2HEKM@201174|Actinobacteria,4EEKA@85010|Pseudonocardiales	201174|Actinobacteria	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_31
BYD2_k127_981239_16	1298863.AUEP01000002_gene1430	7.535e-52	198.0	COG2044@1|root,COG2044@2|Bacteria,2HYH6@201174|Actinobacteria,4DUYV@85009|Propionibacteriales	201174|Actinobacteria	S	PFAM DsrE DsrF-like family	-	-	-	-	-	-	-	-	-	-	-	-	-
BYD2_k127_981239_19	1122238.AULR01000002_gene598	1.441e-30	130.0	COG1652@1|root,COG1652@2|Bacteria,2GK68@201174|Actinobacteria	201174|Actinobacteria	M	domain protein	-	-	-	ko:K21687,ko:K21691	-	-	-	-	ko00000	-	GH23	-	LysM,Transglycosylas
BYD2_k127_981239_3	656024.FsymDg_2687	2.068e-213	694.0	COG2909@1|root,COG2909@2|Bacteria,2GM03@201174|Actinobacteria,4ETTY@85013|Frankiales	201174|Actinobacteria	K	helix_turn_helix, Lux Regulon	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GerE
BYD2_k127_981239_10	1123024.AUII01000013_gene446	9.34e-103	347.0	COG0500@1|root,COG2226@2|Bacteria,2GNXF@201174|Actinobacteria,4E18W@85010|Pseudonocardiales	201174|Actinobacteria	Q	ubiE/COQ5 methyltransferase family	-	-	2.1.1.288	ko:K15942	ko01057,ko01130,map01057,map01130	M00781	R06675,R06680	RC00003,RC00460	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_11,Methyltransf_25
BYD2_k127_981239_15	981369.JQMJ01000004_gene4642	2.172e-59	231.0	COG1695@1|root,COG1695@2|Bacteria,2IHK3@201174|Actinobacteria	201174|Actinobacteria	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR,Vir_act_alpha_C
BYD2_k127_981239_5	469383.Cwoe_0405	7.595e-146	483.0	COG3214@1|root,COG3214@2|Bacteria,2GK0T@201174|Actinobacteria,4CSD5@84995|Rubrobacteria	84995|Rubrobacteria	S	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_42
BYD2_k127_981239_1	710696.Intca_0881	7.721e-309	982.0	COG2866@1|root,COG4412@1|root,COG2866@2|Bacteria,COG4412@2|Bacteria,2GN49@201174|Actinobacteria,4FIMN@85021|Intrasporangiaceae	201174|Actinobacteria	M	Zn_pept	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M14,Peptidase_M6
BYD2_k127_986708_2	1394178.AWOO02000041_gene8838	1.357e-68	241.0	COG3327@1|root,COG3327@2|Bacteria,2HHB2@201174|Actinobacteria,4EIW4@85012|Streptosporangiales	201174|Actinobacteria	K	PaaX-like protein	-	-	-	ko:K02616	-	-	-	-	ko00000,ko03000	-	-	-	PaaX,PaaX_C
BYD2_k127_986708_0	1229780.BN381_30040	2.027e-114	383.0	COG3239@1|root,COG3239@2|Bacteria	2|Bacteria	I	unsaturated fatty acid biosynthetic process	MA20_28095	-	-	-	-	-	-	-	-	-	-	-	FA_desaturase
BYD2_k127_986708_1	357808.RoseRS_0965	6.757e-80	273.0	COG0462@1|root,COG0462@2|Bacteria,2G5T8@200795|Chloroflexi,376D2@32061|Chloroflexia	32061|Chloroflexia	F	Phosphoribosyl synthetase-associated domain	-	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran_N
## 5009 queries scanned
## Total time (seconds): 9.830089330673218
## Rate: 509.56 q/s